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Takashi Kohda

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Takashi Kohda; Fumitoshi Ishino
Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development.
Takashi Kohda; Teruhiko Wakayama; Tomoko Kaneko-Ishino; Satoshi Kishigami; Fumitoshi Ishino
Gene expression profile normalization in cloned mice by trichostatin A treatment.
Takashi Kohda; Narumi Ogonuki; Atsuo Ogura; Tomohiro Suzuki; Shigeharu Wakana; Teruhiko Wakayama; Tamio Furuse; Kimiko Inoue; Hideki Kaneda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Intracytoplasmic sperm injection induces transcriptome perturbation without any transgenerational effect.

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All Publications

2013: Takashi Kohda; Fumitoshi Ishino
Embryo manipulation via assisted reproductive technology and epigenetic asymmetry in mammalian early development.
Philosophical transactions of the Royal Society of London. Series B, Biological sciences 2013;368(1609):20120353.
2012: Takashi Kohda; Teruhiko Wakayama; Tomoko Kaneko-Ishino; Satoshi Kishigami; Fumitoshi Ishino
Gene expression profile normalization in cloned mice by trichostatin A treatment.
Cellular reprogramming 2012;14(1):45-55.
2011: Takashi Kohda; Narumi Ogonuki; Atsuo Ogura; Tomohiro Suzuki; Shigeharu Wakana; Teruhiko Wakayama; Tamio Furuse; Kimiko Inoue; Hideki Kaneda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Intracytoplasmic sperm injection induces transcriptome perturbation without any transgenerational effect.
Biochemical and biophysical research communications 2011;410(2):282-8.
2010: Yoshikazu Yuki; Tomonori Nochi; Norihiro Harada; Yuko Katakai; Hiroaki Shibata; Mio Mejima; Takashi Kohda; Daisuke Tokuhara; Shiho Kurokawa; Yuko Takahashi; Fumiko Ono; Shunji Kozaki; Keiji Terao; Hideo Tsukada; Hiroshi Kiyono
In vivo molecular imaging analysis of a nasal vaccine that induces protective immunity against botulism in nonhuman primates.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(9):5436-43.
2009: Hirosuke Shiura; Kenji Nakamura; Takafusa Hikichi; Toshiaki Hino; Kanako Oda; Rika Suzuki-Migishima; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Paternal deletion of Meg1/Grb10 DMR causes maternalization of the Meg1/Grb10 cluster in mouse proximal Chromosome 11 leading to severe pre- and postnatal growth retardation.
Human molecular genetics 2009;18(8):1424-38.
2008: Yoichi Sekita; H Wagatsuma; Kenji Nakamura; Ryoichi Ono; Masayo Kagami; Noriko Wakisaka; Toshiaki Hino; Rika Suzuki-Migishima; Takashi Kohda; Atsuo Ogura; Tsutomu Ogata; Minesuke Yokoyama; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Role of retrotransposon-derived imprinted gene, Rtl1, in the feto-maternal interface of mouse placenta.
Nature genetics 2008;40(2):243-8.
2007: Shunsuke Suzuki; Ryoichi Ono; Takanori Narita; Andrew J Pask; geoffrey shaw; Changshan Wang; Takashi Kohda; Amber E Alsop; Jennifer A Marshall Graves; Yuji Kohara; Fumitoshi Ishino; Marilyn Renfree; Tomoko Kaneko-Ishino
Retrotransposon silencing by DNA methylation can drive mammalian genomic imprinting.
PLoS genetics 2007;3(4):e55.
2007: Takashi Kohda; Kayoko Tanaka; Mami Konomi; Mamiko Sato; Masako Osumi; Masayuki Yamamoto
Fission yeast autophagy induced by nitrogen starvation generates a nitrogen source that drives adaptation processes.
Genes to cells : devoted to molecular & cellular mechanisms 2007;12(2):155-70.
2007: Yasutomi Kamei; Takayoshi Suganami; Takashi Kohda; Fumitoshi Ishino; Kazuki Yasuda; Shinji Miura; Osamu Ezaki; Yoshihiro Ogawa
Peg1/Mest in obese adipose tissue is expressed from the paternal allele in an isoform-specific manner.
FEBS letters 2007;581(1):91-6.
2006: Noriko Wakisaka-Saito; Takashi Kohda; Kimiko Inoue; Narumi Ogonuki; Hiromi Miki; Takafusa Hikichi; Eiji Mizutani; Teruhiko Wakayama; Tomoko Kaneko-Ishino; Atsuo Ogura; Fumitoshi Ishino
Chorioallantoic placenta defects in cloned mice.
Biochemical and biophysical research communications 2006;349(1):106-14.
2006: Takashi Kohda; Fumitoshi Ishino; Atsuo Ogura
Expression of imprinted genes in cloned mice.
Methods in molecular biology (Clifton, N.J.) 2006;348():237-46.
2006: Y Sekita; H Wagatsuma; M Irie; Shin Kobayashi; Takashi Kohda; J Matsuda; Minesuke Yokoyama; Atsuo Ogura; Karin Schuster-Gossler; Achim Gossler; Fumitoshi Ishino; Tomoko Kaneko-Ishino
Aberrant regulation of imprinted gene expression in Gtl2lacZ mice.
Cytogenetic and genome research 2006;113(1-4):223-9.
2006: Tomoko Kaneko-Ishino; Takashi Kohda; Ryoichi Ono; Fumitoshi Ishino
Complementation hypothesis: the necessity of a monoallelic gene expression mechanism in mammalian development.
Cytogenetic and genome research 2006;113(1-4):24-30.
2006: Ryoichi Ono; Kenji Nakamura; Kimiko Inoue; Mie Naruse; Takako Usami; Noriko Wakisaka-Saito; Toshiaki Hino; Rika Suzuki-Migishima; Narumi Ogonuki; Hiromi Miki; Takashi Kohda; Atsuo Ogura; Minesuke Yokoyama; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Deletion of Peg10, an imprinted gene acquired from a retrotransposon, causes early embryonic lethality.
Nature genetics 2006;38(1):101-6.
2005: Takashi Kohda; Kimiko Inoue; Narumi Ogonuki; Hiromi Miki; Mie Naruse; Tomoko Kaneko-Ishino; Atsuo Ogura; Fumitoshi Ishino
Variation in gene expression and aberrantly regulated chromosome regions in cloned mice.
Biology of reproduction 2005;73(6):1302-11.
2005: Kayoko Tanaka; Takashi Kohda; Akira Yamashita; Nobuhiro Nonaka; Masayuki Yamamoto
Hrs1p/Mcp6p on the meiotic SPB organizes astral microtubule arrays for oscillatory nuclear movement.
Current biology : CB 2005;15(16):1479-86.
2005: Hirosuke Shiura; Naoki Miyoshi; Atsuo Konishi; Noriko Wakisaka-Saito; Rika Suzuki; Kaori Muguruma; Takashi Kohda; Shigeharu Wakana; Minesuke Yokoyama; Fumitoshi Ishino; Tomoko Kaneko-Ishino
Meg1/Grb10 overexpression causes postnatal growth retardation and insulin resistance via negative modulation of the IGF1R and IR cascades.
Biochemical and biophysical research communications 2005;329(3):909-16.
2005: Hiromi Miki; Kimiko Inoue; Takashi Kohda; Arata Honda; Narumi Ogonuki; Misako Yuzuriha; Nathan Mise; Yasuhisa Matsui; Tadashi Baba; Kuniya Abe; Fumitoshi Ishino; Atsuo Ogura
Birth of mice produced by germ cell nuclear transfer.
Genesis (New York, N.Y. : 2000) 2005;41(2):81-6.
2005: Shunsuke Suzuki; Marilyn Renfree; Andrew J Pask; geoffrey shaw; Shin Kobayashi; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Genomic imprinting of IGF2, p57(KIP2) and PEG1/MEST in a marsupial, the tammar wallaby.
Mechanisms of development 2005;122(2):213-22.
2004: Masayuki Kai; Masahito Irie; Tomohisa Okutsu; Kimiko Inoue; Narumi Ogonuki; Hiromi Miki; Minesuke Yokoyama; Rika Migishima; Kaori Muguruma; Hisako Fujimura; Takashi Kohda; Atsuo Ogura; Tomoko Kaneko-Ishino; Fumitoshi Ishino
The novel dominant mutation Dspd leads to a severe spermiogenesis defect in mice.
Biology of reproduction 2004;70(4):1213-21.
2004: Hiromi Miki; Jiyoung Lee; Kimiko Inoue; Narumi Ogonuki; Yoko Noguchi; Keiji Mochida; Takashi Kohda; Hiroshi Nagashima; Fumitoshi Ishino; Atsuo Ogura
Microinsemination with first-wave round spermatids from immature male mice.
The Journal of reproduction and development 2004;50(1):131-7.
2003: Kimiko Inoue; Narumi Ogonuki; Keiji Mochida; Yoshie Yamamoto; Kaoru Takano; Takashi Kohda; Fumitoshi Ishino; Atsuo Ogura
Effects of donor cell type and genotype on the efficiency of mouse somatic cell cloning.
Biology of reproduction 2003;69(4):1394-400.
2003: Ryoichi Ono; Hirosuke Shiura; Hiroyuki Aburatani; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Identification of a large novel imprinted gene cluster on mouse proximal chromosome 6.
Genome research 2003;13(7):1696-705.
2003: Tomoko Kaneko-Ishino; Takashi Kohda; Fumitoshi Ishino
The regulation and biological significance of genomic imprinting in mammals.
Journal of biochemistry 2003;133(6):699-711.
2003: Takafusa Hikichi; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Imprinting regulation of the murine Meg1/Grb10 and human GRB10 genes; roles of brain-specific promoters and mouse-specific CTCF-binding sites.
Nucleic acids research 2003;31(5):1398-406.
2002: Tomoko Kaneko-Ishino; Takashi Kohda; Fumitoshi Ishino
[Epigenetics in cloned mice].
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 2002;47(13):1816-21.
2002: Jiyoung Lee; Kimiko Inoue; Ryoichi Ono; Narumi Ogonuki; Takashi Kohda; Tomoko Kaneko-Ishino; Atsuo Ogura; Fumitoshi Ishino
Erasing genomic imprinting memory in mouse clone embryos produced from day 11.5 primordial germ cells.
Development (Cambridge, England) 2002;129(8):1807-17.
2002: Kimiko Inoue; Takashi Kohda; Jiyoung Lee; Narumi Ogonuki; Keiji Mochida; Yoko Noguchi; Kentaro Tanemura; Tomoko Kaneko-Ishino; Fumitoshi Ishino; Atsuo Ogura
Faithful expression of imprinted genes in cloned mice.
Science (New York, N.Y.) 2002;295(5553):297.
2002: Shin Kobayashi; Takashi Kohda; Hitoshi Ichikawa; Atsuo Ogura; Misao Ohki; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Paternal expression of a novel imprinted gene, Peg12/Frat3, in the mouse 7C region homologous to the Prader-Willi syndrome region.
Biochemical and biophysical research communications 2002;290(1):403-8.
2002: Atsuo Ogura; K Inoue; Narumi Ogonuki; J Lee; Takashi Kohda; Fumitoshi Ishino
Phenotypic effects of somatic cell cloning in the mouse.
Cloning and stem cells 2002;4(4):397-405.
2001: S Kobayashi; H Uemura; Takashi Kohda; T Nagai; Yasutsugu Chinen; Kenji Naritomi; E I Kinoshita; H Ohashi; K Imaizumi; M Tsukahara; Y Sugio; H Tonoki; Tatsuya Kishino; T Tanaka; M Yamada; O Tsutsumi; Norio Niikawa; Tomoko Kaneko-Ishino; Fumitoshi Ishino
No evidence of PEG1/MEST gene mutations in Silver-Russell syndrome patients.
American journal of medical genetics 2001;104(3):225-31.
2001: Ryoichi Ono; Shin Kobayashi; H Wagatsuma; K Aisaka; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
A retrotransposon-derived gene, PEG10, is a novel imprinted gene located on human chromosome 7q21.
Genomics 2001;73(2):232-7.
2001: Takashi Kohda; A Asai; Y Kuroiwa; Shin Kobayashi; K Aisaka; G Nagashima; Masasuke Yoshida; Y Kondo; N Kagiyama; T Kirino; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Tumour suppressor activity of human imprinted gene PEG3 in a glioma cell line.
Genes to cells : devoted to molecular & cellular mechanisms 2001;6(3):237-47.
2001: Fumitoshi Ishino; Y Kuroiwa; N Miyoshi; S Kobayashi; Takashi Kohda; Tomoko Kaneko-Ishino
Subtraction-hybridization method for the identification of imprinted genes.
Methods in molecular biology (Clifton, N.J.) 2001;181():101-12.
2000: Shin Kobayashi; H Wagatsuma; Ryoichi Ono; H Ichikawa; M Yamazaki; H Tashiro; K Aisaka; Naoki Miyoshi; Takashi Kohda; Atsuo Ogura; M Ohki; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Mouse Peg9/Dlk1 and human PEG9/DLK1 are paternally expressed imprinted genes closely located to the maternally expressed imprinted genes: mouse Meg3/Gtl2 and human MEG3.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(12):1029-37.
2000: Naoki Miyoshi; H Wagatsuma; Shigeharu Wakana; Toshihiko Shiroishi; M Nomura; K Aisaka; Takashi Kohda; M Azim Surani; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Identification of an imprinted gene, Meg3/Gtl2 and its human homologue MEG3, first mapped on mouse distal chromosome 12 and human chromosome 14q.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(3):211-20.
2000: Tomohisa Okutsu; Y Kuroiwa; F Kagitani; M Kai; K Aisaka; O Tsutsumi; Y Kaneko; K Yokomori; M Azim Surani; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Expression and imprinting status of human PEG8/IGF2AS, a paternally expressed antisense transcript from the IGF2 locus, in Wilms' tumors.
Journal of biochemistry 2000;127(3):475-83.
1998: Naoki Miyoshi; Y Kuroiwa; Takashi Kohda; H Shitara; H Yonekawa; T Kawabe; H Hasegawa; Sheila C Barton; M Azim Surani; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Identification of the Meg1/Grb10 imprinted gene on mouse proximal chromosome 11, a candidate for the Silver-Russell syndrome gene.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(3):1102-7.
1997: F Kagitani; Y Kuroiwa; Shigeharu Wakana; Toshihiko Shiroishi; Naoki Miyoshi; Shin Kobayashi; M Nishida; Takashi Kohda; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Peg5/Neuronatin is an imprinted gene located on sub-distal chromosome 2 in the mouse.
Nucleic acids research 1997;25(17):3428-32.
1997: Shin Kobayashi; Takashi Kohda; Naoki Miyoshi; Y Kuroiwa; K Aisaka; O Tsutsumi; Tomoko Kaneko-Ishino; Fumitoshi Ishino
Human PEG1/MEST, an imprinted gene on chromosome 7.
Human molecular genetics 1997;6(5):781-6.
1996: Y Kuroiwa; Tomoko Kaneko-Ishino; F Kagitani; Takashi Kohda; L L Li; M Tada; R Suzuki; M Yokoyama; Toshihiko Shiroishi; Shigeharu Wakana; Sheila C Barton; Fumitoshi Ishino; M Azim Surani
Peg3 imprinted gene on proximal chromosome 7 encodes for a zinc finger protein.
Nature genetics 1996;12(2):186-90.
1995: Tomoko Kaneko-Ishino; Y Kuroiwa; Naoki Miyoshi; Takashi Kohda; R Suzuki; M Yokoyama; S Viville; Sheila C Barton; Fumitoshi Ishino; M Azim Surani
Peg1/Mest imprinted gene on chromosome 6 identified by cDNA subtraction hybridization.
Nature genetics 1995;11(1):52-9.