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Leonard Kohn

Research Profile

Anatomy

Chemicals & Drugs

Physiology

Genes & Molecular Sequences

Genes, MHC Class I

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Publications

TOP 3
Mariko Sue; Kazunari Tanigawa; Huhehasi Wu; Aya Yoshihara; Gen Yoshino; Takeshi Akama; Takeshi Hara; Naoki Hiroi; Yuko Ishido; Norihisa Ishii; Akira Kawashima; Leonard D Kohn; Hannah Nakamura; Koichi Suzuki
Propylthiouracil increases sodium/iodide symporter gene expression and iodide uptake in rat thyroid cells in the absence of TSH.
Cesidio Giuliani; Norikazu Harii; Leonard D Kohn; Fabrizio Monaco; Ines Bucci; Dominique Cerrone; Tyler Chamblin; Nilesh M Dagia; Emilio Fiore; Mark Thornton; Paolo Vitti; Giorgio Napolitano
A TSHr-LH/CGr chimera that measures functional TSAb in Graves' disease.
Cesidio Giuliani; Norikazu Harii; Leonard D Kohn; Fabrizio Monaco; Ines Bucci; Maria Carpentieri; Dominique Cerrone; Nilesh M Dagia; Andrea Di Blasio; Barbara Di Nenno; Mark Thornton; Paolo Vitti; Giorgio Napolitano
A TSHR-LH/CGR chimera that measures functional thyroid-stimulating autoantibodies (TSAb) can predict remission or recurrence in Graves' patients undergoing antithyroid drug (ATD) treatment.

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All Publications

2012: Mariko Sue; Kazunari Tanigawa; Huhehasi Wu; Aya Yoshihara; Gen Yoshino; Takeshi Akama; Takeshi Hara; Naoki Hiroi; Yuko Ishido; Norihisa Ishii; Akira Kawashima; Leonard D Kohn; Hannah Nakamura; Koichi Suzuki
Propylthiouracil increases sodium/iodide symporter gene expression and iodide uptake in rat thyroid cells in the absence of TSH.
Thyroid : official journal of the American Thyroid Association 2012;22(8):844-52.
2012: Cesidio Giuliani; Norikazu Harii; Leonard D Kohn; Fabrizio Monaco; Ines Bucci; Dominique Cerrone; Tyler Chamblin; Nilesh M Dagia; Emilio Fiore; Mark Thornton; Paolo Vitti; Giorgio Napolitano
A TSHr-LH/CGr chimera that measures functional TSAb in Graves' disease.
The Journal of clinical endocrinology and metabolism 2012;97(7):E1106-15.
2012: Cesidio Giuliani; Norikazu Harii; Leonard D Kohn; Fabrizio Monaco; Ines Bucci; Maria Carpentieri; Dominique Cerrone; Nilesh M Dagia; Andrea Di Blasio; Barbara Di Nenno; Mark Thornton; Paolo Vitti; Giorgio Napolitano
A TSHR-LH/CGR chimera that measures functional thyroid-stimulating autoantibodies (TSAb) can predict remission or recurrence in Graves' patients undergoing antithyroid drug (ATD) treatment.
The Journal of clinical endocrinology and metabolism 2012;97(7):E1080-7.
2012: Uruguaysito Benavides; Nilesh M Dagia; Cesidio Giuliani; Mariana Gonzalez-Murguiondo; Norikazu Harii; Christopher J Lewis; Ramiro Malgor; Kelly D McCall; Giorgio Napolitano; Anthony L Schwartz; Leonard D Kohn
Phenylmethimazole inhibits production of proinflammatory mediators and is protective in an experimental model of endotoxic shock*.
Critical care medicine 2012;40(3):886-94.
2010: S D Lytton; Y Li; Paul David Olivo; Leonard D Kohn; George J Kahaly
Novel chimeric thyroid-stimulating hormone-receptor bioassay for thyroid-stimulating immunoglobulins.
Clinical and experimental immunology 2010;162(3):438-46.
2010: Uruguaysito Benavides; Mariana Gonzalez-Murguiondo; Norikazu Harii; Christopher J Lewis; Harshad S Sakhalkar; Sudhir P Deosarkar; David T Kurjiaka; Nilesh M Dagia; Douglas J Goetz; Leonard D Kohn
Phenyl methimazole suppresses dextran sulfate sodium-induced murine colitis.
European journal of pharmacology 2010;643(1):129-38.
2010: Koichi Suzuki; Hiroaki Kimura; Huhehasi Wu; Naoko Kudo; Won Bae Kim; Sayuri Suzuki; Akio Yoshida; Patrizio Caturegli; Leonard D Kohn
Excess iodide decreases transcription of NIS and VEGF genes in rat FRTL-5 thyroid cells.
Biochemical and biophysical research communications 2010;393(2):286-90.
2010: China Malakondaiah Kummitha; Kristine M Mayle; Mark A Christman; Sudhir P Deosarkar; Anthony L Schwartz; Kelly D McCall; Leonard D Kohn; Ramiro Malgor; Douglas J Goetz
A sandwich ELISA for the detection of Wnt5a.
Journal of immunological methods 2010;352(1-2):38-44.
2010: Cesidio Giuliani; Ines Bucci; Valeria Montani; dinah singer; Fabrizio Monaco; Leonard D Kohn; Giorgio Napolitano
Regulation of major histocompatibility complex gene expression in thyroid epithelial cells by methimazole and phenylmethimazole.
The Journal of endocrinology 2010;204(1):57-66.
2009: Anthony L Schwartz; Ramiro Malgor; Eric Dickerson; Ashani T Weeraratna; Andrzej Slominski; Jacobo Wortsman; Norikazu Harii; Aimee D Kohn; Randall T Moon; Frank L Schwartz; Douglas J Goetz; Leonard D Kohn; Kelly D McCall
Phenylmethimazole decreases Toll-like receptor 3 and noncanonical Wnt5a expression in pancreatic cancer and melanoma together with tumor cell growth and migration.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(12):4114-22.
2008: Sudhir P Deosarkar; Ramiro Malgor; Jie Fu; Leonard D Kohn; Justin Hanes; Douglas J Goetz
Polymeric particles conjugated with a ligand to VCAM-1 exhibit selective, avid, and focal adhesion to sites of atherosclerosis.
Biotechnology and bioengineering 2008;101(2):400-7.
2008: Mark A Christman; Douglas J Goetz; Eric Dickerson; Kelly D McCall; Christopher J Lewis; Fabian Benencia; Mitchell J Silver; Leonard D Kohn; Ramiro Malgor
Wnt5a is expressed in murine and human atherosclerotic lesions.
American journal of physiology. Heart and circulatory physiology 2008;294(6):H2864-70.
2008: Cesidio Giuliani; Yoshihiko Noguchi; Norikazu Harii; Giorgio Napolitano; Dante Tatone; Ines Bucci; Mauro Piantelli; Fabrizio Monaco; Leonard D Kohn
The flavonoid quercetin regulates growth and gene expression in rat FRTL-5 thyroid cells.
Endocrinology 2008;149(1):84-92.
2007: Kelly D McCall; Norikazu Harii; Christopher J Lewis; Ramiro Malgor; Won Bae Kim; Motoyasu Saji; Aimee D Kohn; Randall T Moon; Leonard D Kohn
High basal levels of functional toll-like receptor 3 (TLR3) and noncanonical Wnt5a are expressed in papillary thyroid cancer and are coordinately decreased by phenylmethimazole together with cell proliferation and migration.
Endocrinology 2007;148(9):4226-37.
2007: Antonino Grassadonia; Nicola Tinari; Bruno Fiorentino; Minoru Nakazato; Hyun-Kyung Chung; Cesidio Giuliani; Giorgio Napolitano; Stefano Iacobelli; T Kevin Howcroft; dinah singer; Leonard D Kohn
Upstream stimulatory factor regulates constitutive expression and hormonal suppression of the 90K (Mac-2BP) protein.
Endocrinology 2007;148(7):3507-17.
2007: Won Bae Kim; Christopher J Lewis; Kelly D McCall; Ramiro Malgor; Aimee D Kohn; Randall T Moon; Leonard D Kohn
Overexpression of Wnt-1 in thyrocytes enhances cellular growth but suppresses transcription of the thyroperoxidase gene via different signaling mechanisms.
The Journal of endocrinology 2007;193(1):93-106.
2006: Cesidio Giuliani; Motoyasu Saji; Ines Bucci; G Fiore; M Liberatore; dinah singer; Fabrizio Monaco; Leonard D Kohn; Giorgio Napolitano
Transcriptional regulation of major histocompatibility complex class I gene by insulin and IGF-I in FRTL-5 thyroid cells.
The Journal of endocrinology 2006;189(3):605-15.
2006: Koichi Suzuki; Leonard D Kohn
Differential regulation of apical and basal iodide transporters in the thyroid by thyroglobulin.
The Journal of endocrinology 2006;189(2):247-55.
2005: Harshad S Sakhalkar; Justin Hanes; Jie Fu; Uruguaysito Benavides; Ramiro Malgor; Cheri L Borruso; Leonard D Kohn; David T Kurjiaka; Douglas J Goetz
Enhanced adhesion of ligand-conjugated biodegradable particles to colitic venules.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(7):792-4.
2005: Norikazu Harii; Christopher J Lewis; Vasilly Vasko; Kelly D McCall; Uruguaysito Benavides-Peralta; Xiaolu Sun; Matthew D Ringel; Motoyasu Saji; Cesidio Giuliani; Giorgio Napolitano; Douglas J Goetz; Leonard D Kohn
Thyrocytes express a functional toll-like receptor 3: overexpression can be induced by viral infection and reversed by phenylmethimazole and is associated with Hashimoto's autoimmune thyroiditis.
Molecular endocrinology (Baltimore, Md.) 2005;19(5):1231-50.
2004: Antonino Grassadonia; Nicola Tinari; Bruno Fiorentino; Koichi Suzuki; Minoru Nakazato; Michele De Tursi; Cesidio Giuliani; Giorgio Napolitano; dinah singer; Stefano Iacobelli; Leonard D Kohn
The 90K protein increases major histocompatibility complex class I expression and is regulated by hormones, gamma-interferon, and double-strand polynucleotides.
Endocrinology 2004;145(10):4728-36.
2004: Akio Yoshida; Ichiro Hisatome; Shinichi Taniguchi; Norihiro Sasaki; Yasutaka Yamamoto; Junichiro Miake; Hiroko Fukui; Hideki Shimizu; Tomohisa Okamura; Tsuyoshi Okura; Osamu Igawa; Chiaki Shigemasa; Eric Green; Leonard D Kohn; Koichi Suzuki
Mechanism of iodide/chloride exchange by pendrin.
Endocrinology 2004;145(9):4301-8.
2004: Nilesh M Dagia; Norikazu Harii; Antonella E Meli; Xiaolu Sun; Christopher J Lewis; Leonard D Kohn; Douglas J Goetz
Phenyl methimazole inhibits TNF-alpha-induced VCAM-1 expression in an IFN regulatory factor-1-dependent manner and reduces monocytic cell adhesion to endothelial cells.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(3):2041-9.
2003: Francesco Pacifico; Nunzia Montuori; Stefano Mellone; Domenico Liguoro; Luca Ulianich; Alessia Caleo; Giancarlo Troncone; Leonard D Kohn; Bruno Di Jeso; Eduardo Consiglio
The RHL-1 subunit of the asialoglycoprotein receptor of thyroid cells: cellular localization and its role in thyroglobulin endocytosis.
Molecular and cellular endocrinology 2003;208(1-2):51-9.
2003: Leonard D Kohn; Norikazu Harii
Thyrotropin receptor autoantibodies (TSHRAbs): epitopes, origins and clinical significance.
Autoimmunity 2003;36(6-7):331-7.
2003: Bertrand Saunier; Miriam Triyatni; Luca Ulianich; Padma Maruvada; Paul M Yen; Leonard D Kohn
Role of the asialoglycoprotein receptor in binding and entry of hepatitis C virus structural proteins in cultured human hepatocytes.
Journal of virology 2003;77(1):546-59.
2002: Pnina Rotman-Pikielny; Koret Hirschberg; Padma Maruvada; Koichi Suzuki; Ines E Royaux; Eric Green; Leonard D Kohn; Jennifer Lippincott-Schwartz; Paul M Yen
Retention of pendrin in the endoplasmic reticulum is a major mechanism for Pendred syndrome.
Human molecular genetics 2002;11(21):2625-33.
2002: Miriam Triyatni; Bertrand Saunier; Padma Maruvada; Anthony R Davis; Luca Ulianich; Theo Heller; Arvind Patel; Leonard D Kohn; TSANYANG LIANG
Interaction of hepatitis C virus-like particles and cells: a model system for studying viral binding and entry.
Journal of virology 2002;76(18):9335-44.
2002: Akio Yoshida; Shinichi Taniguchi; Ichiro Hisatome; Ines E Royaux; Eric Green; Leonard D Kohn; Koichi Suzuki
Pendrin is an iodide-specific apical porter responsible for iodide efflux from thyroid cells.
The Journal of clinical endocrinology and metabolism 2002;87(7):3356-61.
2002: Giorgio Napolitano; Ines Bucci; Cesidio Giuliani; Cinzia Massafra; Cinzia Di Petta; Eleonora Devangelio; dinah singer; Fabrizio Monaco; Leonard D Kohn
High glucose levels increase major histocompatibility complex class I gene expression in thyroid cells and amplify interferon-gamma action.
Endocrinology 2002;143(3):1008-17.
2002: Koichi Suzuki; M Yanagi; Atsumi Mori-Aoki; E Moriyama; K J Ishii; Leonard D Kohn
Transfection of single-stranded hepatitis A virus RNA activates MHC class I pathway.
Clinical and experimental immunology 2002;127(2):234-42.
2002: Koichi Suzuki; Ines E Royaux; Lorraine A Everett; Atsumi Mori-Aoki; Sayuri Suzuki; Kazuaki Nakamura; Takafumi Sakai; Ryohei Katoh; Shuji Toda; Eric Green; Leonard D Kohn
Expression of PDS/Pds, the Pendred syndrome gene, in endometrium.
The Journal of clinical endocrinology and metabolism 2002;87(2):938.
2001: Ken J Ishii; Koichi Suzuki; Cevayir Coban; Fumihiko Takeshita; Y Itoh; H Matoba; Leonard D Kohn; Dennis M Klinman
Genomic DNA released by dying cells induces the maturation of APCs.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(5):2602-7.
2001: J Saito; Aimee D Kohn; Robert A Roth; Y Noguchi; I Tatsumo; A Hirai; K Suzuki; Leonard D Kohn; Motoyasu Saji; Matthew D Ringel
Regulation of FRTL-5 thyroid cell growth by phosphatidylinositol (OH) 3 kinase-dependent Akt-mediated signaling.
Thyroid : official journal of the American Thyroid Association 2001;11(4):339-51.
2001: Leonard D Kohn; Koichi Suzuki; Minoru Nakazato; Ines E Royaux; Eric Green
Effects of thyroglobulin and pendrin on iodide flux through the thyrocyte.
Trends in endocrinology and metabolism: TEM 2001;12(1):10-6.
2000: Atsumi Mori-Aoki; M Pietrarelli; Minoru Nakazato; Patrizio Caturegli; Leonard D Kohn; Koichi Suzuki
Class II transactivator suppresses transcription of thyroid-specific genes.
Biochemical and biophysical research communications 2000;278(1):58-62.
2000: Minoru Nakazato; Hyun-Kyung Chung; Luca Ulianich; Antonino Grassadonia; Koichi Suzuki; Leonard D Kohn
Thyroglobulin repression of thyroid transcription factor 1 (TTF-1) gene expression is mediated by decreased DNA binding of nuclear factor I proteins which control constitutive TTF-1 expression.
Molecular and cellular biology 2000;20(22):8499-512.
2000: Koichi Suzuki; Minoru Nakazato; Luca Ulianich; Atsumi Mori-Aoki; E Moriyama; Hyun-Kyung Chung; M Pietrarelli; Antonino Grassadonia; H Matoba; Leonard D Kohn
Thyroglobulin autoregulation of thyroid-specific gene expression and follicular function.
Reviews in endocrine & metabolic disorders 2000;1(3):217-24.
2000: Diego L Medina; Koichi Suzuki; M Pietrarelli; F Okajima; Leonard D Kohn; Pilar Santisteban
Role of insulin and serum on thyrotropin regulation of thyroid transcription factor-1 and pax-8 genes expression in FRTL-5 thyroid cells.
Thyroid : official journal of the American Thyroid Association 2000;10(4):295-303.
2000: Giorgio Napolitano; V Montani; Cesidio Giuliani; S Di Vincenzo; Ines Bucci; V Todisco; G Laglia; anna coppa; dinah singer; Minoru Nakazato; Leonard D Kohn; Giulia Colletta; Fabrizio Monaco
Transforming growth factor-beta1 down-regulation of major histocompatibility complex class I in thyrocytes: coordinate regulation of two separate elements by thyroid-specific as well as ubiquitous transcription factors.
Molecular endocrinology (Baltimore, Md.) 2000;14(4):486-505.
2000: Cesidio Giuliani; Giorgio Napolitano; Antonio Mastino; S Di Vincenzo; Cartesio D'Agostini; Sandro Grelli; Ines Bucci; dinah singer; Leonard D Kohn; Fabrizio Monaco; Enrico Garaci; Cartesio Favalli
Thymosin-alpha1 regulates MHC class I expression in FRTL-5 cells at transcriptional level.
European journal of immunology 2000;30(3):778-86.
2000: Frank Schuppert; D Ehrenthal; Andrea Frilling; K Suzuki; Giorgio Napolitano; Leonard D Kohn
Increased major histocompatibility complex (MHC) expression in nontoxic goiters is associated with iodide depletion, enhanced ability of the follicular thyroglobulin to increase MHC gene expression, and thyroid autoantibodies.
The Journal of clinical endocrinology and metabolism 2000;85(2):858-67.
2000: Ines E Royaux; Koichi Suzuki; A Mori; R Katoh; Lorraine A Everett; Leonard D Kohn; Eric Green
Pendrin, the protein encoded by the Pendred syndrome gene (PDS), is an apical porter of iodide in the thyroid and is regulated by thyroglobulin in FRTL-5 cells.
Endocrinology 2000;141(2):839-45.
2000: Leonard D Kohn; N Shimojo; Y Kohno; Koichi Suzuki
An animal model of Graves' disease: understanding the cause of autoimmune hyperthyroidism.
Reviews in endocrine & metabolic disorders 2000;1(1-2):59-67.
2000: Leonard D Kohn; Giorgio Napolitano; dinah singer; M Molteni; R Scorza; N Shimojo; Y Kohno; Edna Mozes; Minoru Nakazato; Luca Ulianich; Hyun-Kyung Chung; H Matoba; Bertrand Saunier; Koichi Suzuki; Frank Schuppert; Motoyasu Saji
Graves' disease: a host defense mechanism gone awry.
International reviews of immunology 2000;19(6):633-64.
2000: SL Kirshner; L Palmer; Josef Bodor; Motoyasu Saji; Leonard D Kohn; dinah singer
Major histocompatibility class I gene transcription in thyrocytes: a series of interacting regulatory DNA sequence elements mediate thyrotropin/cyclic adenosine 3',5'-monophosphate repression.
Molecular endocrinology (Baltimore, Md.) 2000;14(1):82-98.
1999: Koichi Suzuki; A Mori; J Saito; E Moriyama; L Ullianich; Leonard D Kohn
Follicular thyroglobulin suppresses iodide uptake by suppressing expression of the sodium/iodide symporter gene.
Endocrinology 1999;140(11):5422-30.
1999: Luca Ulianich; Koichi Suzuki; A Mori; Minoru Nakazato; M Pietrarelli; Paul K Goldsmith; Francesco Pacifico; Eduardo Consiglio; Silvestro Formisano; Leonard D Kohn
Follicular thyroglobulin (TG) suppression of thyroid-restricted genes involves the apical membrane asialoglycoprotein receptor and TG phosphorylation.
The Journal of biological chemistry 1999;274(35):25099-107.
1999: dinah singer; Heidy Zinger; Leonard D Kohn; Edna Mozes
Differing MHC class I requirements for induction and propagation of experimental systemic lupus erythematosus.
European journal of immunology 1999;29(7):2259-68.
1999: Koichi Suzuki; A Mori; S Lavaroni; Luca Ulianich; Eri Miyagi; J Saito; Minoru Nakazato; M Pietrarelli; N Shafran; Antonino Grassadonia; W B Kim; Eduardo Consiglio; Silvestro Formisano; Leonard D Kohn
Thyroglobulin regulates follicular function and heterogeneity by suppressing thyroid-specific gene expression.
Biochimie 1999;81(4):329-40.
1999: Koichi Suzuki; A Mori; S Lavaroni; Eri Miyagi; Luca Ulianich; Ryohei Katoh; Akira Kawaoi; Leonard D Kohn
In vivo expression of thyroid transcription factor-1 RNA and its relation to thyroid function and follicular heterogeneity: identification of follicular thyroglobulin as a feedback suppressor of thyroid transcription factor-1 RNA levels and thyroglobulin synthesis.
Thyroid : official journal of the American Thyroid Association 1999;9(4):319-31.
1999: Koichi Suzuki; A Mori; K J Ishii; J Saito; dinah singer; D M Klinman; P R Krause; Leonard D Kohn
Activation of target-tissue immune-recognition molecules by double-stranded polynucleotides.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(5):2285-90.
1998: Koichi Suzuki; S Lavaroni; A Mori; F Okajima; S Kimura; Ryohei Katoh; Akira Kawaoi; Leonard D Kohn
Thyroid transcription factor 1 is calcium modulated and coordinately regulates genes involved in calcium homeostasis in C cells.
Molecular and cellular biology 1998;18(12):7410-22.
1998: Koichi Suzuki; S Lavaroni; A Mori; M Ohta; J Saito; M Pietrarelli; dinah singer; S Kimura; Ryohei Katoh; Akira Kawaoi; Leonard D Kohn
Autoregulation of thyroid-specific gene transcription by thyroglobulin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(14):8251-6.
1998: Koichi Suzuki; Y Kobayashi; Ryohei Katoh; Leonard D Kohn; Akira Kawaoi
Identification of thyroid transcription factor-1 in C cells and parathyroid cells.
Endocrinology 1998;139(6):3014-7.
1998: P L Balducci-Silano; Koichi Suzuki; M Ohta; J Saito; M Ohmori; V Montani; Giorgio Napolitano; Minho Shong; SI Taniguchi; M Pietrarelli; S Lavaroni; A Mori; dinah singer; Leonard D Kohn
Regulation of major histocompatibility (MHC) class II human leukocyte antigen-DR alpha gene expression in thyrocytes by single strand binding protein-1, a transcription factor that also regulates thyrotropin receptor and MHC class I gene expression.
Endocrinology 1998;139(5):2300-13.
1998: Edna Mozes; Heidy Zinger; Leonard D Kohn; dinah singer
Spontaneous autoimmune disease in (NZB x NZW)F1 mice is ameliorated by treatment with methimazole.
Journal of clinical immunology 1998;18(2):106-13.
1998: SI Taniguchi; Minho Shong; Cesidio Giuliani; Giorgio Napolitano; Motoyasu Saji; V Montani; Koichi Suzuki; dinah singer; Leonard D Kohn
Iodide suppression of major histocompatibility class I gene expression in thyroid cells involves enhancer A and the transcription factor NF-kappa B.
Molecular endocrinology (Baltimore, Md.) 1998;12(1):19-33.
1998: V Montani; Minho Shong; SI Taniguchi; Koichi Suzuki; Cesidio Giuliani; Giorgio Napolitano; J Saito; Motoyasu Saji; Bruno Fiorentino; A M Reimold; dinah singer; Leonard D Kohn
Regulation of major histocompatibility class II gene expression in FRTL-5 thyrocytes: opposite effects of interferon and methimazole.
Endocrinology 1998;139(1):290-302.
1998: V Montani; SI Taniguchi; Minho Shong; Koichi Suzuki; M Ohmori; Cesidio Giuliani; Giorgio Napolitano; Motoyasu Saji; Bruno Fiorentino; A M Reimold; Jenny P-Y Ting; Leonard D Kohn; dinah singer
Major histocompatibility class II HLA-DR alpha gene expression in thyrocytes: counter regulation by the class II transactivator and the thyroid Y box protein.
Endocrinology 1998;139(1):280-9.
1997: Frank Schuppert; EG Rambusch; H Kirchner; J Atzpodien; Leonard D Kohn; Alexander von zur Mühlen
Patients treated with interferon-alpha, interferon-beta, and interleukin-2 have a different thyroid autoantibody pattern than patients suffering from endogenous autoimmune thyroid disease.
Thyroid : official journal of the American Thyroid Association 1997;7(6):837-42.
1997: Nicholas Sarlis; Françoise Brucker-Davis; J P Swift; K Tahara; Leonard D Kohn
Graves' disease following thyrotoxic painless thyroiditis. Analysis of antibody activities against the thyrotropin receptor in two cases.
Thyroid : official journal of the American Thyroid Association 1997;7(6):829-36.
1997: Leonard D Kohn; Koichi Suzuki; W H Hoffman; D Tombaccini; C Marcocci; N Shimojo; Y Watanabe; N Amino; B Y Cho; Y Kohno; A Hirai; K Tahara
Characterization of monoclonal thyroid-stimulating and thyrotropin binding-inhibiting autoantibodies from a Hashimoto's patient whose children had intrauterine and neonatal thyroid disease.
The Journal of clinical endocrinology and metabolism 1997;82(12):3998-4009.
1997: Motoyasu Saji; Minho Shong; Giorgio Napolitano; L A Palmer; SI Taniguchi; M Ohmori; M Ohta; Koichi Suzuki; SL Kirshner; Cesidio Giuliani; dinah singer; Leonard D Kohn
Regulation of major histocompatibility complex class I gene expression in thyroid cells. Role of the cAMP response element-like sequence.
The Journal of biological chemistry 1997;272(32):20096-107.
1997: dinah singer; Edna Mozes; SL Kirshner; Leonard D Kohn
Role of MHC class I molecules in autoimmune disease.
Critical reviews in immunology 1997;17(5-6):463-8.
1996: Martha A Zeiger; M Saji; Patrizio Caturegli; William H Westra; Leonard D Kohn; Michael Levine
Transformation of rat thyroid follicular cells stably transfected with cholera toxin A1 fragment.
Endocrinology 1996;137(12):5392-9.
1996: M Ohmori; M Ohta; H Shimura; Y Shimurat; K Suzuki; Leonard D Kohn
Cloning of the single strand DNA-binding protein important for maximal expression and thyrotropin (TSH)-induced negative regulation of the TSH receptor.
Molecular endocrinology (Baltimore, Md.) 1996;10(11):1407-24.
1996: John S Dallas; S J Cunningham; SA Patibandla; GS Seetharamaiah; J C Morris; K Tahara; Leonard D Kohn; Bellur S Prabhakar
Thyrotropin (TSH) receptor antibodies (TSHrAb) can inhibit TSH-mediated cyclic adenosine 3',5'- monophosphate production in thyroid cells by either blocking TSH binding or affecting a step subsequent to TSH binding.
Endocrinology 1996;137(8):3329-39.
1996: G Laglia; Martha A Zeiger; A Leipricht; Patrizio Caturegli; Michael Levine; Leonard D Kohn; M Saji
Increased cyclic adenosine 3',5'-monophosphate inhibits G protein-coupled activation of phospholipase C in rat FRTL-5 thyroid cells.
Endocrinology 1996;137(8):3170-6.
1996: M Ohmori; H Shimura; Y Shimura; Leonard D Kohn
A Y-box protein is a suppressor factor that decreases thyrotropin receptor gene expression.
Molecular endocrinology (Baltimore, Md.) 1996;10(1):76-89.
1995: Cesidio Giuliani; M Saji; Giorgio Napolitano; L A Palmer; SI Taniguchi; Minho Shong; dinah singer; Leonard D Kohn
Hormonal modulation of major histocompatibility complex class I gene expression involves an enhancer A-binding complex consisting of Fra-2 and the p50 subunit of NF-kappa B.
The Journal of biological chemistry 1995;270(19):11453-62.
1995: H Shimura; Y Shimura; M Ohmori; S Ikuyama; Leonard D Kohn
Single strand DNA-binding proteins and thyroid transcription factor-1 conjointly regulate thyrotropin receptor gene expression.
Molecular endocrinology (Baltimore, Md.) 1995;9(5):527-39.
1995: M Ohmori; H Shimura; Y Shimura; S Ikuyama; Leonard D Kohn
Characterization of an up-stream thyroid transcription factor-1-binding site in the thyrotropin receptor promoter.
Endocrinology 1995;136(1):269-82.
1995: Leonard D Kohn; H Shimura; Y Shimura; A Hidaka; Cesidio Giuliani; Giorgio Napolitano; M Ohmori; G Laglia; M Saji
The thyrotropin receptor.
Vitamins and hormones 1995;50():287-384.
1994: Y Shimura; H Shimura; M Ohmori; S Ikuyama; Leonard D Kohn
Identification of a novel insulin-responsive element in the rat thyrotropin receptor promoter.
The Journal of biological chemistry 1994;269(50):31908-14.
1994: H Shimura; F Okajima; S Ikuyama; Y Shimura; S Kimura; M Saji; Leonard D Kohn
Thyroid-specific expression and cyclic adenosine 3',5'-monophosphate autoregulation of the thyrotropin receptor gene involves thyroid transcription factor-1.
Molecular endocrinology (Baltimore, Md.) 1994;8(8):1049-69.
1994: dinah singer; Leonard D Kohn; Heidy Zinger; Edna Mozes
Methimazole prevents induction of experimental systemic lupus erythematosus in mice.
Journal of immunology (Baltimore, Md. : 1950) 1994;153(2):873-80.
1994: A Hidaka; T Ban; N S Panesar; T Minegishi; Leonard D Kohn; K Tahara
Thyrotropin stimulation of the lutropin/choriogonadotropin receptor: different sites mediate agonist activity and high affinity binding.
Thyroid : official journal of the American Thyroid Association 1994;4(4):447-57.
1993: H Shimura; S Ikuyama; Y Shimura; Leonard D Kohn
The cAMP response element in the rat thyrotropin receptor promoter. Regulation by each decanucleotide of a flanking tandem repeat uses different, additive, and novel mechanisms.
The Journal of biological chemistry 1993;268(32):24125-37.
1993: A Hidaka; F Okajima; T Ban; Shinji Kosugi; Y Kondo; Leonard D Kohn
Receptor cross-talk can optimize assays for autoantibodies to the thyrotropin receptor: effect of phenylisopropyladenosine on adenosine 3',5'-monophosphate and inositol phosphate levels in rat FRTL-5 thyroid cells.
The Journal of clinical endocrinology and metabolism 1993;77(5):1164-9.
1993: A Hidaka; T Minegishi; Leonard D Kohn
Thyrotropin, like luteinizing hormone (LH) and chorionic gonadotropin (CG), increases cAMP and inositol phosphate levels in cells with recombinant human LH/CG receptor.
Biochemical and biophysical research communications 1993;196(1):187-95.
1993: R K Desai; John S Dallas; M K Gupta; GS Seetharamaiah; Jilao Fan; K Tahara; Leonard D Kohn; Bellur S Prabhakar
Dual mechanism of perturbation of thyrotropin-mediated activation of thyroid cells by antibodies to the thyrotropin receptor (TSHR) and TSHR-derived peptides.
The Journal of clinical endocrinology and metabolism 1993;77(3):658-63.
1993: Shinji Kosugi; F Okajima; T Ban; A Hidaka; A Shenker; Leonard D Kohn
Substitutions of different regions of the third cytoplasmic loop of the thyrotropin (TSH) receptor have selective effects on constitutive, TSH-, and TSH receptor autoantibody-stimulated phosphoinositide and 3',5'-cyclic adenosine monophosphate signal generation.
Molecular endocrinology (Baltimore, Md.) 1993;7(8):1009-20.
1993: Edna Mozes; Leonard D Kohn; Frances T Hakim; dinah singer
Resistance of MHC class I-deficient mice to experimental systemic lupus erythematosus.
Science (New York, N.Y.) 1993;261(5117):91-3.
1993: Shinji Kosugi; T Ban; T Akamizu; W Valente; Leonard D Kohn
Use of thyrotropin receptor (TSHR) mutants to detect stimulating TSHR antibodies in hypothyroid patients with idiopathic myxedema, who have blocking TSHR antibodies.
The Journal of clinical endocrinology and metabolism 1993;77(1):19-24.
1993: GS Seetharamaiah; R K Desai; John S Dallas; K Tahara; Leonard D Kohn; Bellur S Prabhakar
Induction of TSH binding inhibitory immunoglobulins with the extracellular domain of human thyrotropin receptor produced using baculovirus expression system.
Autoimmunity 1993;14(4):315-20.
1993: Shinji Kosugi; T Ban; Leonard D Kohn
Identification of thyroid-stimulating antibody-specific interaction sites in the N-terminal region of the thyrotropin receptor.
Molecular endocrinology (Baltimore, Md.) 1993;7(1):114-30.
1992: Shinji Kosugi; T Ban; T Akamizu; Leonard D Kohn
Role of cysteine residues in the extracellular domain and exoplasmic loops of the transmembrane domain of the TSH receptor: effect of mutation to serine on TSH receptor activity and response to thyroid stimulating autoantibodies.
Biochemical and biophysical research communications 1992;189(3):1754-62.
1992: Shinji Kosugi; F Okajima; T Ban; A Hidaka; A Shenker; Leonard D Kohn
Mutation of alanine 623 in the third cytoplasmic loop of the rat thyrotropin (TSH) receptor results in a loss in the phosphoinositide but not cAMP signal induced by TSH and receptor autoantibodies.
The Journal of biological chemistry 1992;267(34):24153-6.
1992: S Ikuyama; H Shimura; J P Hoeffler; Leonard D Kohn
Role of the cyclic adenosine 3',5'-monophosphate response element in efficient expression of the rat thyrotropin receptor promoter.
Molecular endocrinology (Baltimore, Md.) 1992;6(10):1701-15.
1992: M Saji; J Moriarty; T Ban; dinah singer; Leonard D Kohn
Major histocompatibility complex class I gene expression in rat thyroid cells is regulated by hormones, methimazole, and iodide as well as interferon.
The Journal of clinical endocrinology and metabolism 1992;75(3):871-8.
1992: T Ban; Shinji Kosugi; Leonard D Kohn
Specific antibody to the thyrotropin receptor identifies multiple receptor forms in membranes of cells transfected with wild-type receptor complementary deoxyribonucleic acid: characterization of their relevance to receptor synthesis, processing, structure, and function.
Endocrinology 1992;131(2):815-29.
1992: S Ikuyama; H H Niller; H Shimura; T Akamizu; Leonard D Kohn
Characterization of the 5'-flanking region of the rat thyrotropin receptor gene.
Molecular endocrinology (Baltimore, Md.) 1992;6(5):793-804.
1992: M Saji; J Moriarty; T Ban; Leonard D Kohn; dinah singer
Hormonal regulation of major histocompatibility complex class I genes in rat thyroid FRTL-5 cells: thyroid-stimulating hormone induces a cAMP-mediated decrease in class I expression.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(5):1944-8.
1992: Shinji Kosugi; T Ban; T Akamizu; Leonard D Kohn
Identification of separate determinants on the thyrotropin receptor reactive with Graves' thyroid-stimulating antibodies and with thyroid-stimulating blocking antibodies in idiopathic myxedema: these determinants have no homologous sequence on gonadotropin receptors.
Molecular endocrinology (Baltimore, Md.) 1992;6(2):168-80.
1992: M Saji; T Akamizu; M Sanchez; S Obici; enrico vittorio avvedimento; Max E Gottesman; Leonard D Kohn
Regulation of thyrotropin receptor gene expression in rat FRTL-5 thyroid cells.
Endocrinology 1992;130(1):520-33.
1992: Leonard D Kohn; Shinji Kosugi; T Ban; M Saji; S Ikuyama; Cesidio Giuliani; A Hidaka; H Shimura; T Akamizu; K Tahara
Molecular basis for the autoreactivity against thyroid stimulating hormone receptor.
International reviews of immunology 1992;9(2):135-65.
1991: Shinji Kosugi; T Ban; T Akamizu; Leonard D Kohn
Further characterization of a high affinity thyrotropin binding site on the rat thyrotropin receptor which is an epitope for blocking antibodies from idiopathic myxedema patients but not thyroid stimulating antibodies from Graves' patients.
Biochemical and biophysical research communications 1991;180(2):1118-24.
1991: Shinji Kosugi; T Ban; T Akamizu; Leonard D Kohn
Site-directed mutagenesis of a portion of the extracellular domain of the rat thyrotropin receptor important in autoimmune thyroid disease and nonhomologous with gonadotropin receptors. Relationship of functional and immunogenic domains.
The Journal of biological chemistry 1991;266(29):19413-8.
1991: K Tahara; T Ban; T Minegishi; Leonard D Kohn
Immunoglobulins from Graves' disease patients interact with different sites on TSH receptor/LH-CG receptor chimeras than either TSH or immunoglobulins from idiopathic myxedema patients.
Biochemical and biophysical research communications 1991;179(1):70-7.
1991: O Takai; R K Desai; GS Seetharamaiah; C A Jones; G P Allaway; T Akamizu; Leonard D Kohn; Bellur S Prabhakar
Prokaryotic expression of the thyrotropin receptor and identification of an immunogenic region of the protein using synthetic peptides.
Biochemical and biophysical research communications 1991;179(1):319-26.
1991: T Akamizu; M Saji; S Ikuyama; Shinji Kosugi; K Tahara; Leonard D Kohn
The TSH receptor in autoimmune Basedow's disease.
Experimental and clinical endocrinology 1991;97(2-3):153-9.
1991: M Saji; S Ikuyama; T Akamizu; Leonard D Kohn
Increases in cytosolic Ca++ down regulate thyrotropin receptor gene expression by a mechanism different from the cAMP signal.
Biochemical and biophysical research communications 1991;176(1):94-101.
1991: M Saji; Leonard D Kohn
Insulin and insulin-like growth factor-I inhibit thyrotropin-increased iodide transport in serum-depleted FRTL-5 rat thyroid cells: modulation of adenosine 3',5'-monophosphate signal action.
Endocrinology 1991;128(2):1136-43.
1991: K Tahara; Evelyn F Grollman; M Saji; Leonard D Kohn
Regulation of prostaglandin synthesis by thyrotropin, insulin or insulin-like growth factor-I, and serum in FRTL-5 rat thyroid cells.
The Journal of biological chemistry 1991;266(1):440-8.
1991: Shinji Kosugi; T Akamizu; O Takai; Bellur S Prabhakar; Leonard D Kohn
The extracellular domain of the TSH receptor has an immunogenic epitope reactive with Graves' IgG but unrelated to receptor function as well as determinants having different roles for high affinity TSH binding and the activity of thyroid-stimulating autoantibodies.
Thyroid : official journal of the American Thyroid Association 1991;1(4):321-30.
1990: M Saji; Leonard D Kohn
Effect of hydrocortisone on the ability of thyrotropin to increase deoxyribonucleic acid synthesis and iodide uptake in FRTL-5 rat thyroid cells: opposite regulation of adenosine 3',5'-monophosphate signal action.
Endocrinology 1990;127(4):1867-76.
1990: S Bellur; K Tahara; M Saji; Evelyn F Grollman; Leonard D Kohn
Repeatedly passed FRTL-5 rat thyroid cells can develop insulin and insulin-like growth factor-I-sensitive cyclooxygenase and prostaglandin E2 isomerase-like activities together with altered basal and thyrotropin-responsive thymidine incorporation into DNA.
Endocrinology 1990;127(3):1526-40.
1990: T Akamizu; S Ikuyama; M Saji; Shinji Kosugi; C Kozak; O W McBride; Leonard D Kohn
Cloning, chromosomal assignment, and regulation of the rat thyrotropin receptor: expression of the gene is regulated by thyrotropin, agents that increase cAMP levels, and thyroid autoantibodies.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(15):5677-81.
1990: T Akamizu; M Saji; Leonard D Kohn
A microsequencing approach to identify proteins which appear to interact with thyrotropin in rat FRTL-5 thyroid cells.
Biochemical and biophysical research communications 1990;170(1):351-8.
1990: J P Coutelier; John Kehrl; S S Bellur; Leonard D Kohn; Abner Louis Notkins; Bellur S Prabhakar
Binding and functional effects of thyroid stimulating hormone on human immune cells.
Journal of clinical immunology 1990;10(4):204-10.
1990: T Akamizu; Shinji Kosugi; Leonard D Kohn
Thyrotropin receptor processing and interaction with thyrotropin.
Biochemical and biophysical research communications 1990;169(3):947-52.
1990: G P Allaway; A A Vivino; Leonard D Kohn; Abner Louis Notkins; Bellur S Prabhakar
Characterization of the 70KDA component of the human Ku autoantigen expressed in insect cell nuclei using a recombinant baculovirus vector.
Biochemical and biophysical research communications 1990;168(2):747-55.
1990: S M Aloj; Domenico Grieco; A D Kohn; Vera M Nikodem; Leonard D Kohn
Thyrotropin regulation of malic enzyme in FRTL-5 rat thyroid cells.
Molecular endocrinology (Baltimore, Md.) 1990;4(4):611-22.
1989: O Isozaki; Leonard D Kohn; C A Kozak; S Kimura
Thyroid peroxidase: rat cDNA sequence, chromosomal localization in mouse, and regulation of gene expression by comparison to thyroglobulin in rat FRTL-5 cells.
Molecular endocrinology (Baltimore, Md.) 1989;3(11):1681-92.
1989: R Zarrilli; E L Oates; O W McBride; M I Lerman; J Y Chan; P Santisteban; M V Ursini; A L Notkins; Leonard D Kohn
Sequence and chromosomal assignment of a novel cDNA identified by immunoscreening of a thyroid expression library: similarity to a family of mitochondrial solute carrier proteins.
Molecular endocrinology (Baltimore, Md.) 1989;3(9):1498-505.
1989: J Y Chan; M I Lerman; Bellur S Prabhakar; O Isozaki; P Santisteban; R C Kuppers; E L Oates; A L Notkins; Leonard D Kohn
Cloning and characterization of a cDNA that encodes a 70-kDa novel human thyroid autoantigen.
The Journal of biological chemistry 1989;264(7):3651-4.
1989: A D Kohn; J Chan; Domenico Grieco; Vera M Nikodem; S M Aloj; Leonard D Kohn
Thyrotropin increases malic enzyme messenger ribonucleic acid levels in rat FRTL-5 thyroid cells.
Molecular endocrinology (Baltimore, Md.) 1989;3(3):532-8.
1989: Leonard D Kohn; M Saji; T Akamizu; S Ikuyama; O Isozaki; A D Kohn; P Santisteban; J Y Chan; S Bellur; C M Rotella
Receptors of the thyroid: the thyrotropin receptor is only the first violinist of a symphony orchestra.
Advances in experimental medicine and biology 1989;261():151-209.
1989: N Perrotti; C M Rotella; F V Alvarez; Leonard D Kohn; S Taylor
Characterization of receptors for insulin and insulin-like growth factor-1 on FRTL-5 thyroid cells.
Advances in experimental medicine and biology 1989;261():105-19.
1989: K Tahara; M Saji; S M Aloj; Leonard D Kohn
The arachidonic acid signal system in the thyroid: regulation by thyrotropin and insulin/IGF-I.
Advances in experimental medicine and biology 1989;261():295-326.
1987: O Isozaki; Leonard D Kohn
Control of c-fos and c-myc proto-oncogene induction in rat thyroid cells in culture.
Molecular endocrinology (Baltimore, Md.) 1987;1(11):839-48.
1987: J Chan; P Santisteban; M De Luca; O Isozaki; Evelyn F Grollman; Leonard D Kohn
TSH receptor structure.
Acta endocrinologica. Supplementum 1987;281():166-72.
1987: O Isozaki; P Santisteban; J Chan; Evelyn F Grollman; Leonard D Kohn
Insulin and insulin-like growth factor-I (IGF-I) regulate differentiation as well as growth in FRTL-5 cells.
Acta endocrinologica. Supplementum 1987;281():288-92.
1987: Evelyn F Grollman; E Bone; J Chan; D Corda; O Isozaki; C Marcocci; P Santisteban; Leonard D Kohn
TSH and biogenic amine signals in the regulation of thyroid function: independent regulation by protein kinase C and G proteins.
Acta endocrinologica. Supplementum 1987;281():199-202.
1986: Carlo Maria Rotella; R Zonefrati; R Toccafondi; W A Valente; Leonard D Kohn
Ability of monoclonal antibodies to the thyrotropin receptor to increase collagen synthesis in human fibroblasts: an assay which appears to measure exophthalmogenic immunoglobulins in Graves' sera.
The Journal of clinical endocrinology and metabolism 1986;62(2):357-67.
1986: Leonard D Kohn; F Alvarez; C Marcocci; A D Kohn; D Corda; W E Hoffman; D Tombaccini; W A Valente; M de Luca; P Santisteban
Monoclonal antibody studies defining the origin and properties of autoantibodies in Graves' disease.
Annals of the New York Academy of Sciences 1986;475():157-73.
1984: P Lacetti; D Tombaccini; S Aloj; Evelyn F Grollman; Leonard D Kohn
Gangliosides, the thyrotropin receptor, and autoimmune thyroid disease.
Advances in experimental medicine and biology 1984;174():355-67.
1983: C Marcocci; W A Valente; A Pinchera; S M Aloj; Leonard D Kohn; Evelyn F Grollman
Graves' IgG stimulation of iodide uptake in FRTL-5 rat thyroid cells: a clinical assay complementing FRTL-5 assays measuring adenylate cyclase and growth-stimulating antibodies in autoimmune thyroid disease.
Journal of endocrinological investigation 1983;6(6):463-71.
1983: W A Valente; Paolo Vitti; Carlo Maria Rotella; M M Vaughan; S M Aloj; Evelyn F Grollman; F S Ambesi-Impiombato; Leonard D Kohn
Antibodies that promote thyroid growth. A distinct population of thyroid-stimulating autoantibodies.
The New England journal of medicine 1983;309(17):1028-34.
1983: Paolo Vitti; Carlo Maria Rotella; W A Valente; J Cohen; S M Aloj; P Laccetti; F S Ambesi-Impiombato; Evelyn F Grollman; A Pinchera; R Toccafondi; Leonard D Kohn
Characterization of the optimal stimulatory effects of graves' monoclonal and serum immunoglobulin G on adenosine 3',5'-monophosphate production in fRTL-5 thyroid cells: a potential clinical assay.
The Journal of clinical endocrinology and metabolism 1983;57(4):782-91.
1983: Ephraim Yavin; Z Yavin; Leonard D Kohn
Temperature-mediated interaction of tetanus toxin with cerebral neuron cultures: characterization of a neuraminidase-insensitive toxin-receptor complex.
Journal of neurochemistry 1983;40(5):1212-9.
1983: P Laccetti; Evelyn F Grollman; S M Aloj; Leonard D Kohn
Ganglioside dependent return of TSH receptor function in a rat thyroid tumor with a TSH receptor defect.
Biochemical and biophysical research communications 1983;110(3):772-8.
1983: Leonard D Kohn; W A Valente; P Laccetti; J L Cohen; S M Aloj; Evelyn F Grollman
Multicomponent structure of the thyrotropin receptor: relationship to Graves' disease.
Life sciences 1983;32(1-2):15-30.
1983: W A Valente; Paolo Vitti; Leonard D Kohn; M L Brandi; Carlo Maria Rotella; R Toccafondi; Donatella Tramontano; S M Aloj; F S Ambesi-Impiombato
The relationship of growth and adenylate cyclase activity in cultured thyroid cells: separate bioeffects of thyrotropin.
Endocrinology 1983;112(1):71-9.
1982: W A Valente; Paolo Vitti; Z Yavin; Ephraim Yavin; Carlo Maria Rotella; Evelyn F Grollman; R S Toccafondi; Leonard D Kohn
Monoclonal antibodies to the thyrotropin receptor: stimulating and blocking antibodies derived from the lymphocytes of patients with Graves disease.
Proceedings of the National Academy of Sciences of the United States of America 1982;79(21):6680-4.
1982: W A Valente; Z Yavin; Ephraim Yavin; Evelyn F Grollman; M Schneider; Carlo Maria Rotella; R Zonefrati; R S Toccafondi; Leonard D Kohn
Monoclonal antibodies to the thyrotropin receptor: the identification of blocking and stimulating antibodies.
Journal of endocrinological investigation 1982;5(5):293-301.
1982: Paolo Vitti; W A Valente; F S Ambesi-Impiombato; G F Fenzi; A Pinchera; Leonard D Kohn
Graves' IgG stimulation of continuously cultured rat thyroid cells: a sensitive and potentially useful clinical assay.
Journal of endocrinological investigation 1982;5(3):179-82.
1982: Z Yavin; Ephraim Yavin; Leonard D Kohn
Sequestration of tetanus toxin in developing neuronal cell cultures.
Journal of neuroscience research 1982;7(3):267-78.
1982: Leonard D Kohn; S M Aloj; Francesco Beguinot; Paolo Vitti; Ephraim Yavin; Z Yavin; P Laccetti; Evelyn F Grollman; W A Valente
Molecular interactions at the cell surface: role of glycoconjugates and membrane lipids in receptor recognition processes.
Progress in clinical and biological research 1982;97():55-83.
1981: M J De Wolf; Paolo Vitti; F S Ambesi-Impiombato; Leonard D Kohn
Thyroid membrane ADP ribosyltransferase activity. Stimulation by thyrotropin and activity in functioning and nonfunctioning rat thyroid cells in culture.
The Journal of biological chemistry 1981;256(23):12287-96.
1981: R L Goldberg; T Costa; W H Habig; Leonard D Kohn; M C Hardegree
Characterization of fragment C and tetanus toxin binding to rat brain membranes.
Molecular pharmacology 1981;20(3):565-70.
1981: Ephraim Yavin; Z Yavin; W H Habig; M C Hardegree; Leonard D Kohn
Tetanus toxin association with developing neuronal cell cultures. Kinetic parameters and evidence for ganglioside-mediated internalization.
The Journal of biological chemistry 1981;256(13):7014-22.
1981: Ephraim Yavin; Z Yavin; M D Schneider; Leonard D Kohn
Monoclonal antibodies to the thyrotropin receptor: implications for receptor structure and the action of autoantibodies in Graves disease.
Proceedings of the National Academy of Sciences of the United States of America 1981;78(5):3180-4.
1980: N P Morris; E Consiglio; Leonard D Kohn; W H Habig; M C Hardegree; T B Helting
Interaction of fragments B and C of tetanus toxin with neural and thyroid membranes and with gangliosides.
The Journal of biological chemistry 1980;255(13):6071-6.