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Caroline Köhrer

Research Profile

Chemicals & Drugs

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Ribosomes

Genes & Molecular Sequences

Suppressor Genes

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Publications

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Asha Ivy Jacob; Caroline Köhrer; Uttam L RajBhandary; Bryan W Davies; Graham Charles Walker
Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation.
Bryan W Davies; Caroline Köhrer; Asha I Jacob; Lyle A Simmons; Jianyu Zhu; Lourdes M Aleman; Uttam L RajBhandary; Graham C Walker
Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing.
Debabrata Mandal; Caroline Köhrer; Dan Su; Susan P Russell; Kady Krivos; Colette M Castleberry; Paul Blum; Patrick A Limbach; Dieter Söll; Uttam L RajBhandary
Agmatidine, a modified cytidine in the anticodon of archaeal tRNA(Ile), base pairs with adenosine but not with guanosine.

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All Publications

2013: Asha Ivy Jacob; Caroline Köhrer; Uttam L RajBhandary; Bryan W Davies; Graham Charles Walker
Conserved bacterial RNase YbeY plays key roles in 70S ribosome quality control and 16S rRNA maturation.
Molecular cell 2013;49(3):427-38.
2010: Bryan W Davies; Caroline Köhrer; Asha I Jacob; Lyle A Simmons; Jianyu Zhu; Lourdes M Aleman; Uttam L RajBhandary; Graham C Walker
Role of Escherichia coli YbeY, a highly conserved protein, in rRNA processing.
Molecular microbiology 2010;78(2):506-18.
2010: Debabrata Mandal; Caroline Köhrer; Dan Su; Susan P Russell; Kady Krivos; Colette M Castleberry; Paul Blum; Patrick A Limbach; Dieter Söll; Uttam L RajBhandary
Agmatidine, a modified cytidine in the anticodon of archaeal tRNA(Ile), base pairs with adenosine but not with guanosine.
Proceedings of the National Academy of Sciences of the United States of America 2010;107(7):2872-7.
2008: Caroline Köhrer; Uttam L RajBhandary
The many applications of acid urea polyacrylamide gel electrophoresis to studies of tRNAs and aminoacyl-tRNA synthetases.
Methods (San Diego, Calif.) 2008;44(2):129-38.
2008: Shixin Ye; Caroline Köhrer; Thomas Huber; Manija A Kazmi; Pallavi Sachdev; Elsa C Y Yan; Aditi Bhagat; Uttam L RajBhandary; Thomas P Sakmar
Site-specific incorporation of keto amino acids into functional G protein-coupled receptors using unnatural amino acid mutagenesis.
The Journal of biological chemistry 2008;283(3):1525-33.
2008: Caroline Köhrer; Gayathri Srinivasan; Debabrata Mandal; Bibekanand Mallick; Zhumur Ghosh; Jayprokas Chakrabarti; Uttam L RajBhandary
Identification and characterization of a tRNA decoding the rare AUA codon in Haloarcula marismortui.
RNA (New York, N.Y.) 2008;14(1):117-26.
2007: Caroline Köhrer; Uttam L RajBhandary
An evolved ribosome for genetic code expansion.
Nature biotechnology 2007;25(7):745-6.
2006: Uttam L RajBhandary; Caroline Köhrer
Early days of tRNA research: discovery, function, purification and sequence analysis.
Journal of biosciences 2006;31(4):439-51.
2006: Xiang-Lei Yang; Francella J Otero; Karla L Ewalt; Jianming Liu; Manal A Swairjo; Caroline Köhrer; Uttam L RajBhandary; Robert J Skene; Duncan E McRee; Paul Schimmel
Two conformations of a crystalline human tRNA synthetase-tRNA complex: implications for protein synthesis.
The EMBO journal 2006;25(12):2919-29.
2004: Caroline Köhrer; Eric L Sullivan; Uttam L RajBhandary
Complete set of orthogonal 21st aminoacyl-tRNA synthetase-amber, ochre and opal suppressor tRNA pairs: concomitant suppression of three different termination codons in an mRNA in mammalian cells.
Nucleic acids research 2004;32(21):6200-11.
2003: Caroline Köhrer; Jae-Ho Yoo; Michael Bennett; Jerome Schaack; Uttam L RajBhandary
A possible approach to site-specific insertion of two different unnatural amino acids into proteins in mammalian cells via nonsense suppression.
Chemistry & biology 2003;10(11):1095-102.
2003: Christine Mayer; Caroline Köhrer; Eimear Kenny; Carsten Prusko; Uttam L RajBhandary
Anticodon sequence mutants of Escherichia coli initiator tRNA: effects of overproduction of aminoacyl-tRNA synthetases, methionyl-tRNA formyltransferase, and initiation factor 2 on activity in initiation.
Biochemistry 2003;42(17):4787-99.
2002: alexandre ambrogelly; Ivan Ahel; Carla Polycarpo; Shipra Bunjun-Srihari; Bethany Krett; Clarisse Jacquin-Becker; Benfang Ruan; Caroline Köhrer; Constantinos Stathopoulos; Uttam L RajBhandary; Dieter Söll
Methanocaldococcus jannaschii prolyl-tRNA synthetase charges tRNA(Pro) with cysteine.
The Journal of biological chemistry 2002;277(38):34749-54.
2002: Vaidyanathan Ramesh; Caroline Köhrer; Uttam L RajBhandary
Expression of Escherichia coli methionyl-tRNA formyltransferase in Saccharomyces cerevisiae leads to formylation of the cytoplasmic initiator tRNA and possibly to initiation of protein synthesis with formylmethionine.
Molecular and cellular biology 2002;22(15):5434-42.
2001: Caroline Köhrer; L Xie; S Kellerer; Umesh Varshney; Uttam L RajBhandary
Import of amber and ochre suppressor tRNAs into mammalian cells: a general approach to site-specific insertion of amino acid analogues into proteins.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(25):14310-5.
2001: Christine Mayer; Alexei Stortchevoi; Caroline Köhrer; Umesh Varshney; Uttam L RajBhandary
Initiator tRNA and its role in initiation of protein synthesis.
Cold Spring Harbor symposia on quantitative biology 2001;66():195-206.