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Erkki Koivunen

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Liliana Guzman-Rojas; Yun-Gon Kim; Erkki Koivunen; Mikhail G Kolonin; Wadih Arap; Eleonora Dondossola; Julianna K Edwards; Ricardo Giordano; Roberto Rangel; Alan Saghatelian; Ahmad Salameh; Richard L Sidman; Fernanda I Staquicini; Renata Pasqualini
Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment.
Roberto Rangel; E Helene Sage; Richard L Sidman; Fernanda I Staquicini; E Magda Barbu; Juri G Gelovani; Liliana Guzman-Rojas; Hitomi Hosoya; Kenneth Dunner Jr; Erkki Koivunen; Robert R Langley; Lucia G le Roux; Roy R Lobb; Jing Nie; Michael G Ozawa; Renata Pasqualini; Wadih Arap
Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells.
Fernanda I Staquicini; Jessica Sun; Martin Trepel; Patricia Troncoso; Shi-Ming Tu; Michael J Wallace; Nalvo F Almeida; Gregory H Botz; Dolores J Cahill; Marina Cardó-Vila; Emmanuel Dias-Neto; Kim-Ahn Do; Julianna K Edwards; Eleni Efstathiou; Anne L Flamm; Jeffrey E Gershenwald; Erkki Koivunen; Mikhail G Kolonin; Stan Krajewski; Christopher J Logothetis; Jeffrey J Molldrem; Diana N Nunes; David J O'Connell; Renata Pasqualini; Rebecca D Pentz; Anna Sergeeva; João C Setubal; Richard L Sidman; Wadih Arap
Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients.

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All Publications

2012: Liliana Guzman-Rojas; Yun-Gon Kim; Erkki Koivunen; Mikhail G Kolonin; Wadih Arap; Eleonora Dondossola; Julianna K Edwards; Ricardo Giordano; Roberto Rangel; Alan Saghatelian; Ahmad Salameh; Richard L Sidman; Fernanda I Staquicini; Renata Pasqualini
Cooperative effects of aminopeptidase N (CD13) expressed by nonmalignant and cancer cells within the tumor microenvironment.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(5):1637-42.
2012: Roberto Rangel; E Helene Sage; Richard L Sidman; Fernanda I Staquicini; E Magda Barbu; Juri G Gelovani; Liliana Guzman-Rojas; Hitomi Hosoya; Kenneth Dunner Jr; Erkki Koivunen; Robert R Langley; Lucia G le Roux; Roy R Lobb; Jing Nie; Michael G Ozawa; Renata Pasqualini; Wadih Arap
Combinatorial targeting and discovery of ligand-receptors in organelles of mammalian cells.
Nature communications 2012;3():788.
2011: Fernanda I Staquicini; Jessica Sun; Martin Trepel; Patricia Troncoso; Shi-Ming Tu; Michael J Wallace; Nalvo F Almeida; Gregory H Botz; Dolores J Cahill; Marina Cardó-Vila; Emmanuel Dias-Neto; Kim-Ahn Do; Julianna K Edwards; Eleni Efstathiou; Anne L Flamm; Jeffrey E Gershenwald; Erkki Koivunen; Mikhail G Kolonin; Stan Krajewski; Christopher J Logothetis; Jeffrey J Molldrem; Diana N Nunes; David J O'Connell; Renata Pasqualini; Rebecca D Pentz; Anna Sergeeva; João C Setubal; Richard L Sidman; Wadih Arap
Vascular ligand-receptor mapping by direct combinatorial selection in cancer patients.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(46):18637-42.
2011: Katja Karjalainen; Diana E Jaalouk; Carlos E Bueso-Ramos; Amado J Zurita; Akihiko Kuniyasu; Bedrich Eckhardt; Frank C Marini; Benjamin Lichtiger; Susan O'Brien; Hagop M Kantarjian; Jorge E Cortes; Erkki Koivunen; Wadih Arap; Renata Pasqualini
Targeting neuropilin-1 in human leukemia and lymphoma.
Blood 2011;117(3):920-7.
2010: J Reunanen; Tanja-Maria Ranta; Oula Peñate-Medina; Juho Suojanen; Timo Sorsa; Tuula Salo; Erkki Koivunen; Per E J Saris
A chimera of green fluorescent protein with gelatinase binding and tumor targeting peptide.
Protein expression and purification 2010;72(2):234-7.
2010: Ping Wu; Janne Weisell; Miikka Pakkala; Mikael Peräkylä; Lei Zhu; Riitta Koistinen; Erkki Koivunen; Ulf-Håkan Stenman; Ale Närvänen; Hannu Koistinen
Identification of novel peptide inhibitors for human trypsins.
Biological chemistry 2010;391(2-3):283-93.
2009: Juho Suojanen; Tuula Salo; Erkki Koivunen; Timo Sorsa; Emma Pirilä
A novel and selective membrane type-1 matrix metalloproteinase (MT1-MMP) inhibitor reduces cancer cell motility and tumor growth.
Cancer biology & therapy 2009;8(24):2362-70.
2009: Michael Stefanidakis; Katja Karjalainen; Diana E Jaalouk; Carl G Gahmberg; Susan O'Brien; Renata Pasqualini; Wadih Arap; Erkki Koivunen
Role of leukemia cell invadosome in extramedullary infiltration.
Blood 2009;114(14):3008-17.
2009: Paul J Mintz; Marina Cardó-Vila; Michael G Ozawa; Amin Hajitou; Roberto Rangel; Liliana Guzman-Rojas; Dawn Christianson; Marco A Arap; Ricardo Giordano; Glauco R Souza; Jeffrey Easley; Ahmad Salameh; Salvatore Oliviero; Ricardo R Brentani; Erkki Koivunen; Wadih Arap; Renata Pasqualini
An unrecognized extracellular function for an intracellular adapter protein released from the cytoplasm into the tumor microenvironment.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(7):2182-7.
2008: Esa Jantunen; Maija Itälä; Timo Siitonen; Taru Kuittinen; J Heiskanen; Erkki Koivunen; Eeva Juvonen; R Silvennoinen; Tapio Nousiainen; Pirjo Koistinen; Liisa Volin; Kari Remes
Blood stem cell mobilization and collection in patients with chronic lymphocytic leukaemia: a nationwide analysis.
Bone marrow transplantation 2008;41(3):239-44.
2007: Juho Suojanen; Tuula Salo; Timo Sorsa; Erkki Koivunen
AlphaMbeta2 integrin modulator exerts antitumor activity in vivo.
Anticancer research 2007;27(6B):3775-81.
2007: Pirjo Koistinen; Riikka Räty; Maija Itälä; Esa Jantunen; Erkki Koivunen; Tapio Nousiainen; Tarja-Terttu Pelliniemi; Kari Remes; Tapani Ruutu; Eeva-Riitta Savolainen; Timo Siitonen; Raija Silvennoinen; Liisa Volin; Erkki Elonen
Long-term outcome of intensive chemotherapy for adults with de novo acute myeloid leukaemia (AML): the nationwide AML-92 study by the Finnish Leukaemia Group.
European journal of haematology 2007;78(6):477-86.
2006: Michael Stefanidakis; Erkki Koivunen
Cell-surface association between matrix metalloproteinases and integrins: role of the complexes in leukocyte migration and cancer progression.
Blood 2006;108(5):1441-50.
2006: Esa Jantunen; Maija Itälä; Timo Siitonen; Erkki Koivunen; Sirpa Leppä; Eeva Juvonen; Outi Kuittinen; Tuula Lehtinen; Pirjo Koistinen; Heidi Nyman; Tapio Nousiainen; Liisa Volin; Kari Remes
Late non-relapse mortality among adult autologous stem cell transplant recipients: a nation-wide analysis of 1,482 patients transplanted in 1990-2003.
European journal of haematology 2006;77(2):114-9.
2006: Esa Jantunen; Maija Itälä; Timo Siitonen; Eeva Juvonen; Erkki Koivunen; Pirjo Koistinen; Liisa Volin; Kari Remes; Tapio Nousiainen
Autologous stem cell transplantation in patients with chronic lymphocytic leukaemia: the Finnish experience.
Bone marrow transplantation 2006;37(12):1093-8.
2006: Can Hekim; Jari Leinonen; Ale Närvänen; Hannu Koistinen; Lei Zhu; Erkki Koivunen; Ville Väisänen; Ulf-Hakan Stenman
Novel peptide inhibitors of human kallikrein 2.
The Journal of biological chemistry 2006;281(18):12555-60.
2006: Päivi Heikkilä; Juho Suojanen; Emma Pirilä; Anu Väänänen; Erkki Koivunen; Timo Sorsa; Tuula Salo
Human tongue carcinoma growth is inhibited by selective antigelatinolytic peptides.
International journal of cancer. Journal international du cancer 2006;118(9):2202-9.
2006: Mikael Björklund; Olli Aitio; Michael Stefanidakis; Juho Suojanen; Tuula Salo; Timo Sorsa; Erkki Koivunen
Stabilization of the activated alphaMbeta2 integrin by a small molecule inhibits leukocyte migration and recruitment.
Biochemistry 2006;45(9):2862-71.
2006: Esa Jantunen; Maija Itälä; Tuula Lehtinen; Outi Kuittinen; Erkki Koivunen; Sirpa Leppä; Eeva Juvonen; Pirjo Koistinen; T Wiklund; Tapio Nousiainen; Kari Remes; Liisa Volin
Early treatment-related mortality in adult autologous stem cell transplant recipients: a nation-wide survey of 1482 transplanted patients.
European journal of haematology 2006;76(3):245-50.
2005: P E M H Litjens; Gijsbert van Willigen; C Weeterings; Martin J W IJsseldijk; Marjolijn van Lier; Erkki Koivunen; Carl G Gahmberg; Jan-Willem N Akkerman
A tripeptide mimetic of von Willebrand factor residues 981-983 enhances platelet adhesion to fibrinogen by signaling through integrin alpha(IIb)beta3.
Journal of thrombosis and haemostasis : JTH 2005;3(6):1274-83.
2005: Mikael Björklund; Erkki Koivunen
Gelatinase-mediated migration and invasion of cancer cells.
Biochimica et biophysica acta 2005;1755(1):37-69.
2005: Esa Jantunen; Erkki Koivunen; Mervi Putkonen; Timo Siitonen; Eeva Juvonen; Tapio Nousiainen
Autologous stem cell transplantation in patients with high-risk plasmacytoma.
European journal of haematology 2005;74(5):402-6.
2005: Oula Penate Medina; Kalevi Kairemo; Heli Valtanen; Aino Kangasniemi; Sami Kaukinen; Ilona Ahonen; Perttu Permi; Arto Annila; Mia Sneck; Juha M Holopainen; Sirkka-Liisa Karonen; Paavo K J Kinnunen; Erkki Koivunen
Radionuclide imaging of tumor xenografts in mice using a gelatinase-targeting peptide.
Anticancer research 2005;25(1A):33-42.
2004: Esa Jantunen; Timo Siitonen; Mervi Putkonen; Erkki Koivunen; Eeva Juvonen; Tapio Nousiainen; Pirjo Koistinen
Autologous stem cell transplantation in patients with primary amyloidosis: a nation-wide survey.
Leukemia & lymphoma 2004;45(12):2485-9.
2004: Esa Jantunen; Jarno Salonen; Eeva Juvonen; Erkki Koivunen; Timo Siitonen; Tuula Lehtinen; Outi Kuittinen; Sirpa Leppä; V-J Anttila; Maija Itälä; T Wiklund; Kari Remes; Tapio Nousiainen
Invasive fungal infections in autologous stem cell transplant recipients: a nation-wide study of 1188 transplanted patients.
European journal of haematology 2004;73(3):174-8.
2004: Mikael Björklund; Pia Heikkilä; Erkki Koivunen
Peptide inhibition of catalytic and noncatalytic activities of matrix metalloproteinase-9 blocks tumor cell migration and invasion.
The Journal of biological chemistry 2004;279(28):29589-97.
2004: Michael Stefanidakis; Terhi Ruohtula; Niels Borregaard; Carl G Gahmberg; Erkki Koivunen
Intracellular and cell surface localization of a complex between alphaMbeta2 integrin and promatrix metalloproteinase-9 progelatinase in neutrophils.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7060-8.
2004: Michael Stefanidakis; Erkki Koivunen
Peptide-mediated delivery of therapeutic and imaging agents into mammalian cells.
Current pharmaceutical design 2004;10(24):3033-44.
2004: Tapani Ruutu; Erkki Koivunen; Tapio Nousiainen; Tarja-Terttu Pelliniemi; A Almqvist; Pekka Anttila; Esa Jantunen; Pirjo Koistinen; A Koponen; M Mikkola; Kalevi Oksanen; T Pulli; Kari Remes; R Sarkkinen; R Silvennoinen; Timo Timonen; S Vanhatalo; Erkki Elonen
Oral treatment of acute myeloid leukaemia with etoposide, thioguanine, and idarubicin (ETI) in elderly patients: a prospective randomised comparison with intravenous cytarabine, idarubicin, and thioguanine in the second and third treatment cycle.
European journal of haematology 2004;72(1):38-44.
2003: Michael Stefanidakis; Mikael Bjorklund; Eveliina Ihanus; Carl G Gahmberg; Erkki Koivunen
Identification of a negatively charged peptide motif within the catalytic domain of progelatinases that mediates binding to leukocyte beta 2 integrins.
The Journal of biological chemistry 2003;278(36):34674-84.
2003: Mikael Björklund; Heli Valtanen; Harri Savilahti; Erkki Koivunen
Use of intein-directed peptide biosynthesis to improve serum stability and bioactivity of a gelatinase inhibitory peptide.
Combinatorial chemistry & high throughput screening 2003;6(1):29-35.
2002: Wadih Arap; Mikhail G Kolonin; Martin Trepel; Johanna Lahdenranta; Marina Cardó-Vila; Ricardo Giordano; Paul J Mintz; Peter U Ardelt; Virginia J Yao; Claudia I Vidal; Limor Chen; Anne L Flamm; Heli Valtanen; Lisa M Weavind; Marshall E Hicks; Raphael E Pollock; Gregory H Botz; Corazon D Bucana; Erkki Koivunen; Dolores Cahill; Patricia Troncoso; Keith A Baggerly; Rebecca D Pentz; Kim-Anh Do; Christopher J Logothetis; Renata Pasqualini
Steps toward mapping the human vasculature by phage display.
Nature medicine 2002;8(2):121-7.
2001: Emma Pirilä; Päivi Maisi; Tuula Salo; Erkki Koivunen; Timo Sorsa
In vivo localization of gelatinases (MMP-2 and -9) by in situ zymography with a selective gelatinase inhibitor.
Biochemical and biophysical research communications 2001;287(3):766-74.
2001: Erkki Koivunen; T M Ranta; Arto Annila; S Taube; A Uppala; M Jokinen; Gijsbert van Willigen; Eveliina Ihanus; Carl G Gahmberg
Inhibition of beta(2) integrin-mediated leukocyte cell adhesion by leucine-leucine-glycine motif-containing peptides.
The Journal of cell biology 2001;153(5):905-16.
2001: Annukka Paju; Timo Sorsa; Taina Tervahartiala; Erkki Koivunen; Caj Haglund; Arto Leminen; Torsten Wahlström; Tuula Salo; Ulf-Hakan Stenman
The levels of trypsinogen isoenzymes in ovarian tumour cyst fluids are associated with promatrix metalloproteinase-9 but not promatrix metalloproteinase-2 activation.
British journal of cancer 2001;84(10):1363-71.
2001: Oula Penate Medina; Tim Söderlund; Liisa Laakkonen; Esa K J Tuominen; Erkki Koivunen; Paavo K J Kinnunen
Binding of novel peptide inhibitors of type IV collagenases to phospholipid membranes and use in liposome targeting to tumor cells in vitro.
Cancer research 2001;61(10):3978-85.
2000: A Uppala; Erkki Koivunen
Targeting of phage display vectors to mammalian cells.
Combinatorial chemistry & high throughput screening 2000;3(5):373-92.
2000: P Wu; Jari Leinonen; Erkki Koivunen; Hilkka Lankinen; Ulf-Hakan Stenman
Identification of novel prostate-specific antigen-binding peptides modulating its enzyme activity.
European journal of biochemistry / FEBS 2000;267(20):6212-20.
2000: A Lukkonen; Timo Sorsa; Tuula Salo; Taina Tervahartiala; Erkki Koivunen; Lorne M Golub; S Simon; Ulf-Hakan Stenman
Down-regulation of trypsinogen-2 expression by chemically modified tetracyclines: association with reduced cancer cell migration.
International journal of cancer. Journal international du cancer 2000;86(4):577-81.
2000: Renata Pasqualini; Erkki Koivunen; Renate Kain; Johanna Lahdenranta; M Sakamoto; A Stryhn; R A Ashmun; Linda H. Shapiro; Wadih Arap; Erkki Ruoslahti
Aminopeptidase N is a receptor for tumor-homing peptides and a target for inhibiting angiogenesis.
Cancer research 2000;60(3):722-7.
2000: Jari Leinonen; P Wu; Erkki Koivunen; Ale Närvänen; Ulf-Hakan Stenman
Development of novel peptide ligands modulating the enzyme activity of prostate-specific antigen.
Scandinavian journal of clinical and laboratory investigation. Supplementum 2000;233():59-64.
1999: Tuomas Heiskanen; Ake Lundkvist; Rabah Soliymani; Erkki Koivunen; Antti Vaheri; Hilkka Lankinen
Phage-displayed peptides mimicking the discontinuous neutralization sites of puumala Hantavirus envelope glycoproteins.
Virology 1999;262(2):321-32.
1999: Erkki Koivunen; Wadih Arap; Heli Valtanen; A Rainisalo; Oula Penate Medina; Päivi Heikkilä; C Kantor; Carl G Gahmberg; Tuula Salo; Yrjö T Konttinen; Timo Sorsa; Erkki Ruoslahti; Renata Pasqualini
Tumor targeting with a selective gelatinase inhibitor.
Nature biotechnology 1999;17(8):768-74.
1999: Erkki Koivunen; Wadih Arap; Daniel Rajotte; Johanna Lahdenranta; Renata Pasqualini
Identification of receptor ligands with phage display peptide libraries.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1999;40(5):883-8.
1999: Erkki Koivunen; B H Restel; Daniel Rajotte; Johanna Lahdenranta; Martin Hagedorn; Wadih Arap; Renata Pasqualini
Integrin-binding peptides derived from phage display libraries.
Methods in molecular biology (Clifton, N.J.) 1999;129():3-17.
1998: Daniel Rajotte; Wadih Arap; Martin Hagedorn; Erkki Koivunen; Renata Pasqualini; Erkki Ruoslahti
Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display.
The Journal of clinical investigation 1998;102(2):430-7.
1998: Erkki Elonen; A Almqvist; A Hänninen; Sten-Erik Jansson; G Järventie; Pirjo Koistinen; Erkki Koivunen; R Lahtinen; M Lehtinen; Tapio Nousiainen; Tarja-Terttu Pelliniemi; Allan Rajamäki; Kari Remes; Timo Timonen; Juhani Vilpo; Liisa Volin; Tapani Ruutu
Comparison between four and eight cycles of intensive chemotherapy in adult acute myeloid leukemia: a randomized trial of the Finnish Leukemia Group.
Leukemia 1998;12(7):1041-8.
1998: S Kekomäki; Liisa Volin; Pirjo Koistinen; Erkki Koivunen; Salme Koskimies; Tapani Ruutu; Timo Timonen; Riitta Kekomäki
Successful treatment of platelet transfusion refractoriness: the use of platelet transfusions matched for both human leucocyte antigens (HLA) and human platelet alloantigens (HPA) in alloimmunized patients with leukaemia.
European journal of haematology 1998;60(2):112-8.
1997: T Pulli; Erkki Koivunen; Timo Hyypiä
Cell-surface interactions of echovirus 22.
The Journal of biological chemistry 1997;272(34):21176-80.
1997: Timo Sorsa; Tuula Salo; Erkki Koivunen; Jaana Tyynelä; Yrjö T Konttinen; Ulrich Bergmann; Ari Tuuttila; E Niemi; Olli Teronen; Päivi Heikkilä; H Tschesche; Jari Leinonen; S Osman; Ulf-Hakan Stenman
Activation of type IV procollagenases by human tumor-associated trypsin-2.
The Journal of biological chemistry 1997;272(34):21067-74.
1997: Renata Pasqualini; Erkki Koivunen; Erkki Ruoslahti
Alpha v integrins as receptors for tumor targeting by circulating ligands.
Nature biotechnology 1997;15(6):542-6.
1997: Tapani Ruutu; A Hänninen; G Järventie; Pirjo Koistinen; Erkki Koivunen; K Kätkä; Tapio Nousiainen; Kalevi Oksanen; Tarja-Terttu Pelliniemi; Kari Remes; Timo Timonen; Liisa Volin; Erkki Elonen
Intensive chemotherapy of poor prognosis myelodysplastic syndromes (MDS) and acute myeloid leukemia following MDS with idarubicin and cytarabine.
Leukemia research 1997;21(2):133-8.
1996: Renata Pasqualini; S Bourdoulous; Erkki Koivunen; V L Woods; Erkki Ruoslahti
A polymeric form of fibronectin has antimetastatic effects against multiple tumor types.
Nature medicine 1996;2(11):1197-203.
1996: R Pasqualini; Erkki Koivunen; E Ruoslahti
Peptides in cell adhesion: powerful tools for the study of integrin-ligand interactions.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 1996;29(9):1151-8.
1996: O Itkonen; Ulf-Hakan Stenman; S Osman; Erkki Koivunen; H Halila; T Schröder
Serum samples from pancreatectomized patients contain trypsinogen immunoreactivity.
The Journal of laboratory and clinical medicine 1996;128(1):98-102.
1995: B Wang; Liliane A Dickinson; Erkki Koivunen; E Ruoslahti; Terumi Kohwi-Shigematsu
A novel matrix attachment region DNA binding motif identified using a random phage peptide library.
The Journal of biological chemistry 1995;270(40):23239-42.
1995: R Pasqualini; Erkki Koivunen; E Ruoslahti
A peptide isolated from phage display libraries is a structural and functional mimic of an RGD-binding site on integrins.
The Journal of cell biology 1995;130(5):1189-96.
1995: Erkki Koivunen; B Wang; E Ruoslahti
Phage libraries displaying cyclic peptides with different ring sizes: ligand specificities of the RGD-directed integrins.
Bio/technology (Nature Publishing Company) 1995;13(3):265-70.
1994: Erkki Koivunen; B Wang; E Ruoslahti
Isolation of a highly specific ligand for the alpha 5 beta 1 integrin from a phage display library.
The Journal of cell biology 1994;124(3):373-80.
1994: Tapani Ruutu; A Almqvist; H Hallman; T Honkanen; E Järvenpää; G Järventie; Pirjo Koistinen; Erkki Koivunen; R Lahtinen; M Lehtinen
Oral induction and consolidation of acute myeloid leukemia with etoposide, 6-thioguanine, and idarubicin (ETI) in elderly patients: a randomized comparison with 5-day TAD. Finnish Leukemia Group.
Leukemia 1994;8(1):11-5.
1993: Erkki Koivunen; D A Gay; E Ruoslahti
Selection of peptides binding to the alpha 5 beta 1 integrin from phage display library.
The Journal of biological chemistry 1993;268(27):20205-10.
1991: I P Palva; A Almqvist; Erkki Elonen; A Hänninen; J Jouppila; G Järventie; Erkki Koivunen; K Kätkä; R Lahtinen; T Oivanen
Value of maintenance therapy with chemotherapy or interferon during remission of acute myeloid leukaemia.
European journal of haematology 1991;47(3):229-33.
1991: Erkki Koivunen; A Ristimäki; O Itkonen; S Osman; M Vuento; Ulf-Hakan Stenman
Tumor-associated trypsin participates in cancer cell-mediated degradation of extracellular matrix.
Cancer research 1991;51(8):2107-12.
1991: Erkki Koivunen; Olli Saksela; O Itkonen; S Osman; M L Huhtala; Ulf-Hakan Stenman
Human colon carcinoma, fibrosarcoma and leukemia cell lines produce tumor-associated trypsinogen.
International journal of cancer. Journal international du cancer 1991;47(4):592-6.
1991: Ulf-Hakan Stenman; Erkki Koivunen; O Itkonen
Biology and function of tumor-associated trypsin inhibitor, TATI.
Scandinavian journal of clinical and laboratory investigation. Supplementum 1991;207():5-9.
1990: O Itkonen; Erkki Koivunen; M Hurme; Henrik Alfthan; T Schröder; Ulf-Hakan Stenman
Time-resolved immunofluorometric assays for trypsinogen-1 and 2 in serum reveal preferential elevation of trypsinogen-2 in pancreatitis.
The Journal of laboratory and clinical medicine 1990;115(6):712-8.
1990: Erkki Koivunen; O Itkonen; H Halila; Ulf-Hakan Stenman
Cyst fluid of ovarian cancer patients contains high concentrations of trypsinogen-2.
Cancer research 1990;50(8):2375-8.
1989: Erkki Koivunen; M L Huhtala; Ulf-Hakan Stenman
Human ovarian tumor-associated trypsin. Its purification and characterization from mucinous cyst fluid and identification as an activator of pro-urokinase.
The Journal of biological chemistry 1989;264(24):14095-9.
1989: Erkki Koivunen
Detection of trypsin- and chymotrypsin-like proteases using p-nitroanilide substrates after sodium dodecyl sulphate polyacrylamide gel electrophoresis.
Journal of chromatography 1989;470(2):401-6.
1989: Ulf-Hakan Stenman; Erkki Koivunen; O Itkonen; Ursula Turpeinen; H Halila; M L Huhtala
Tumour-associated trypsin inhibitor, TATI. Clinical use and biological function.
Annales chirurgiae et gynaecologiae 1989;78(1):77-82.
1988: Ursula Turpeinen; Erkki Koivunen; Ulf-Hakan Stenman
Reaction of a tumour-associated trypsin inhibitor with serine proteinases associated with coagulation and tumour invasion.
The Biochemical journal 1988;254(3):911-4.
1988: M K Heiskala; Ulf-Hakan Stenman; Erkki Koivunen; Olli Carpén; Eero Saksela; Tuomo Timonen
Characteristics of soluble tumour-derived proteins that inhibit natural killer activity.
Scandinavian journal of immunology 1988;28(1):19-27.
1988: Ulf-Hakan Stenman; Erkki Koivunen; M Vuento
Characterization of a tumor-associated serine protease.
Biological chemistry Hoppe-Seyler 1988;369 Suppl():9-14.
1988: M Lehtinen; E Soppi; Erkki Koivunen; G Järventie
[Deep venous thrombosis in a young athlete].
Duodecim; lääketieteellinen aikakauskirja 1988;104(14):1073-6.
1987: T Pettersson; Erkki Koivunen; M Ilvonen; J Jouppila; E Aalto; C Wasastjerna
Sarcoidosis and multiple myeloma: an association.
British medical journal (Clinical research ed.) 1987;295(6604):958.
1987: Ursula Turpeinen; Erkki Koivunen; Ulf-Hakan Stenman
Liquid-chromatographic determination of beta 2-microglobulin, alpha 1-acid glycoprotein, and albumin in urine.
Clinical chemistry 1987;33(10):1756-60.
1987: Oskari Heikinheimo; Pekka Lähteenmäki; Erkki Koivunen; D Shoupe; H Croxatto; Tapani Luukkainen; P Lähteenmäki
Metabolism and serum binding of RU 486 in women after various single doses.
Human reproduction (Oxford, England) 1987;2(5):379-85.