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Shuji Kojima

Research Profile

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Gamma Rays

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Publications

TOP 3
Kanako Masumoto; Mitsutoshi Tsukimoto; Shuji Kojima
Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage.
Hayato Sakaki; Mitsutoshi Tsukimoto; Takuya Fujiwaki; Hitoshi Harada; Ayumi Kawano; Shuji Kojima
P2X4 receptor regulates P2X7 receptor-dependent IL-1β and IL-18 release in mouse bone marrow-derived dendritic cells.
Makiko Ishimaru; Hitoshi Harada; Mitsutoshi Tsukimoto; Shuji Kojima
Involvement of P2Y₁₁ receptor in IFN-γ-induced IL-6 production in human keratinocytes.

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All Publications

2013: Kanako Masumoto; Mitsutoshi Tsukimoto; Shuji Kojima
Role of TRPM2 and TRPV1 cation channels in cellular responses to radiation-induced DNA damage.
Biochimica et biophysica acta 2013;1830(6):3382-90.
2013: Hayato Sakaki; Mitsutoshi Tsukimoto; Takuya Fujiwaki; Hitoshi Harada; Ayumi Kawano; Shuji Kojima
P2X4 receptor regulates P2X7 receptor-dependent IL-1β and IL-18 release in mouse bone marrow-derived dendritic cells.
Biochemical and biophysical research communications 2013;432(3):406-11.
2013: Makiko Ishimaru; Hitoshi Harada; Mitsutoshi Tsukimoto; Shuji Kojima
Involvement of P2Y₁₁ receptor in IFN-γ-induced IL-6 production in human keratinocytes.
European journal of pharmacology 2013;703(1-3):67-73.
2013: Hayato Sakaki; Mitsutoshi Tsukimoto; Hitoshi Harada; Yoshinori Moriyama; Shuji Kojima
Autocrine Regulation of Macrophage Activation via Exocytosis of ATP and Activation of P2Y11 Receptor.
PloS one 2013;8(4):e59778.
2012: Fumie Hattori; Hiroshi Kitani; Hitoshi Harada; Yasuhiro Ohshima; Mitsuru Sato; Shizuka Seki; Akina Suzuki; Erina Takai; Takato Takenouchi; Mitsutoshi Tsukimoto; Shuji Kojima
Feasibility study of B16 melanoma therapy using oxidized ATP to target purinergic receptor P2X7.
European journal of pharmacology 2012;695(1-3):20-6.
2012: Erina Takai; Mitsutoshi Tsukimoto; Hitoshi Harada; Yoshinori Moriyama; Keisuke Sawada; Shuji Kojima
Autocrine regulation of TGF-β1-induced cell migration by exocytosis of ATP and activation of P2 receptors in human lung cancer cells.
Journal of cell science 2012;125(Pt 21):5051-60.
2012: Naoko Nishimaki; Mitsutoshi Tsukimoto; Akihiro Kitami; Shuji Kojima
Autocrine regulation of γ-irradiation-induced DNA damage response via extracellular nucleotides-mediated activation of P2Y6 and P2Y12 receptors.
DNA repair 2012;11(8):657-65.
2012: Yasuhiro Ohshima; Mitsutoshi Tsukimoto; Hitoshi Harada; Shuji Kojima
Involvement of connexin43 hemichannel in ATP release after γ-irradiation.
Journal of radiation research 2012;53(4):551-7.
2012: Shinya Yano; Mitsutoshi Tsukimoto; Hitoshi Harada; Shuji Kojima
Involvement of P2Y13 receptor in suppression of neuronal differentiation.
Neuroscience letters 2012;518(1):5-9.
2012: Ayumi Kawano; Hiroshi Kitani; Hitoshi Harada; Daisuke Mori; Taisei Noguchi; Takato Takenouchi; Mitsutoshi Tsukimoto; Shuji Kojima
Regulation of P2X7-dependent inflammatory functions by P2X4 receptor in mouse macrophages.
Biochemical and biophysical research communications 2012;420(1):102-7.
2012: Ayumi Kawano; Hiroshi Kitani; Hitoshi Harada; Noriyuki Hotta; Taisei Noguchi; Takato Takenouchi; Mitsutoshi Tsukimoto; Shuji Kojima
Involvement of P2X4 receptor in P2X7 receptor-dependent cell death of mouse macrophages.
Biochemical and biophysical research communications 2012;419(2):374-80.
2011: Yasuhiro Ohshima; Mitsutoshi Tsukimoto; Ayumi Kawano; Akihiro Kitami; Shuji Kojima
Induction of extracellular ATP mediates increase in intracellular thioredoxin in RAW264.7 cells exposed to low-dose γ-rays.
Free radical biology & medicine 2011;51(6):1240-8.
2011: Hiroko Nakatsukasa; Mitsutoshi Tsukimoto; Hitoshi Harada; Shuji Kojima
Adenosine A2B receptor antagonist suppresses differentiation to regulatory T cells without suppressing activation of T cells.
Biochemical and biophysical research communications 2011;409(1):114-9.
2011: Nana Tamaishi; Mitsutoshi Tsukimoto; Akihiro Kitami; Shuji Kojima
P2Y6 receptors and ADAM17 mediate low-dose gamma-ray-induced focus formation (activation) of EGF receptor.
Radiation research 2011;175(2):193-200.
2011: Emi Satoh; Mitsutoshi Tsukimoto; Shuji Kojima
Involvement of P2Y receptors in the protective effect of ATP towards the cell damage in HaCaT cells exposed to H₂O₂.
The Journal of toxicological sciences 2011;36(6):741-50.
2011: Emi Sato; Mitsutoshi Tsukimoto; Noriko Shimura; Akira Awaya; Shuji Kojima
Mechanism of pigmentation by minocycline in murine B16 melanoma cells.
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2011;131(5):731-8.
2010: Hiroko Nakatsukasa; Mitsutoshi Tsukimoto; Akihiro Tokunaga; Shuji Kojima
Repeated gamma irradiation attenuates collagen-induced arthritis via up-regulation of regulatory T cells but not by damaging lymphocytes directly.
Radiation research 2010;174(3):313-24.
2010: Akihiro Tokunaga; Mitsutoshi Tsukimoto; Hitoshi Harada; Yoshinori Moriyama; Shuji Kojima
Involvement of SLC17A9-dependent vesicular exocytosis in the mechanism of ATP release during T cell activation.
The Journal of biological chemistry 2010;285(23):17406-16.
2010: Mitsutoshi Tsukimoto; Takujiro Homma; Yasuhiro Ohshima; Shuji Kojima
Involvement of purinergic signaling in cellular response to gamma radiation.
Radiation research 2010;173(3):298-309.
2010: Nao Shimoda; Yasuko Mutou; Noriko Shimura; Mitsutoshi Tsukimoto; Akira Awaya; Shuji Kojima
Effect of heterocyclic pyrimidine compounds on UVB-induced cell damage in human keratinocytes and on melanogenesis in mouse B16 cells.
Biological & pharmaceutical bulletin 2010;33(5):862-8.
2010: Mitsutoshi Tsukimoto; Nana Tamaishi; Takujiro Homma; Shuji Kojima
Low-dose gamma-ray irradiation induces translocation of Nrf2 into nuclear in mouse macrophage RAW264.7 cells.
Journal of radiation research 2010;51(3):349-53.
2010: Yasuhiro Ohshima; Mitsutoshi Tsukimoto; Takato Takenouchi; Hitoshi Harada; Akina Suzuki; Mitsuru Sato; Hiroshi Kitani; Shuji Kojima
gamma-Irradiation induces P2X(7) receptor-dependent ATP release from B16 melanoma cells.
Biochimica et biophysica acta 2010;1800(1):40-6.
2009: Masanobu Sakai; Keichiro Yamashita; Naoya Takemoto; Yasuhiro Ohshima; Mitsutoshi Tsukimoto; Yusuke Shinkai; Ken Takeda; Shigeru Oshio; Shuji Kojima
Diesel exhaust (DE) aggravates pathology of delayed-type hypersensitivity (DTH) induced by methyl-bovine serum albumin (mBSA) in mice.
The Journal of toxicological sciences 2009;34(5):483-92.
2009: Mitsutoshi Tsukimoto; Akihiro Tokunaga; Hitoshi Harada; Shuji Kojima
Blockade of murine T cell activation by antagonists of P2Y6 and P2X7 receptors.
Biochemical and biophysical research communications 2009;384(4):512-8.
2009: Keichiro Yamashita; Masanobu Sakai; Naoya Takemoto; Mitsutoshi Tsukimoto; Katsumi Uchida; Hiroshi Yajima; Shigeru Oshio; Ken Takeda; Shuji Kojima
Attenuation of delayed-type hypersensitivity by fullerene treatment.
Toxicology 2009;261(1-2):19-24.
2009: Mitsutoshi Tsukimoto; Takujiro Homma; Yasuko Mutou; Shuji Kojima
0.5 Gy gamma radiation suppresses production of TNF-alpha through up-regulation of MKP-1 in mouse macrophage RAW264.7 cells.
Radiation research 2009;171(2):219-24.
2008: Mitsutoshi Tsukimoto; Hiroko Nakatsukasa; Keigo Sugawara; Keiichiro Yamashita; Shuji Kojima
Repeated 0.5-Gy gamma irradiation attenuates experimental autoimmune encephalomyelitis with up-regulation of regulatory T cells and suppression of IL17 production.
Radiation research 2008;170(4):429-36.
2008: Hiroko Nakatsukasa; Mitsutoshi Tsukimoto; Yasuhiro Ohshima; Fumitoshi Tago; Ayako Masada; Shuji Kojima
Suppressing effect of low-dose gamma-ray irradiation on collagen-induced arthritis.
Journal of radiation research 2008;49(4):381-9.
2007: Yasuko Mutou; Yuko Ibuki; Shuji Kojima
Immunomodulatory effects of ultraviolet B irradiation on atopic dermatitis in NC/Nga mice.
Photodermatology, photoimmunology & photomedicine 2007;23(4):135-44.
2006: Shuji Kojima
[Induction of glutathione and activation of immune functions by low-dose, whole-body irradiation with gamma-rays].
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 2006;126(10):849-57.
2006: Mareyuki Takahashi; Shuji Kojima
Suppression of atopic dermatitis and tumor metastasis in mice by small amounts of radon.
Radiation research 2006;165(3):337-42.
2005: Manami Monobe; Makiko Hino; Mariko Sumi; Akiko Uzawa; Ryoichi Hirayama; Koichi Ando; Shuji Kojima
Protective effects of melatonin on gamma-ray induced intestinal damage.
International journal of radiation biology 2005;81(11):855-60.
2005: Takashi Tanaka; Fumitoshi Tago; Su-Ping Fang; Noriko Shimura; Shuji Kojima
Repeated 0.5-Gy gamma-ray irradiation attenuates autoimmune manifestations in MRL-lpr/lpr mice.
International journal of radiation biology 2005;81(10):731-40.
2005: Su-ping Fang; Fumitoshi Tago; Takashi Tanaka; Noriko Simura; Yasuko Muto; Resuke Goto; Shuji Kojima
Repeated irradiations with gamma-rays at a Dose of 0.5 Gy may exacerbate asthma.
Journal of radiation research 2005;46(2):151-6.
2005: Su-ping Fang; Takeshi Tanaka; Fumitoshi Tago; Takuya Okamoto; Shuji Kojima
Immunomodulatory effects of gyokuheifusan on INF-gamma/IL-4 (Th1/Th2) balance in ovalbumin (OVA)-induced asthma model mice.
Biological & pharmaceutical bulletin 2005;28(5):829-33.
2005: Risa Kurozumi; Mareyuki Takahashi; Shuji Kojima
Involvement of mitochondrial peroxynitrite in nitric oxide-induced glutathione synthesis.
Biological & pharmaceutical bulletin 2005;28(5):779-85.
2005: Manami Monobe; Akiko Uzawa; Makiko Hino; Koichi Ando; Shuji Kojima
Glycine betaine, a beer component, protects radiation-induced injury.
Journal of radiation research 2005;46(1):117-21.
2004: Shuji Kojima; Keiko Nakayama; Hirokazu Ishida
Low dose gamma-rays activate immune functions via induction of glutathione and delay tumor growth.
Journal of radiation research 2004;45(1):33-9.
2003: Yasunori Kawakita; Masahiko Ikekita; Risa Kurozumi; Shuji Kojima
Increase of intracellular glutathione by low-dose gamma-ray irradiation is mediated by transcription factor AP-1 in RAW 264.7 cells.
Biological & pharmaceutical bulletin 2003;26(1):19-23.
2002: Shuji Kojima; Hirokazu Ishida; Mareyuki Takahashi; Kiyonori Yamaoka
Elevation of glutathione induced by low-dose gamma rays and its involvement in increased natural killer activity.
Radiation research 2002;157(3):275-80.