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Prasanna Kolatkar

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Irene Aksoy; Gireesh K Bogu; Jiaxuan Chen; Ushashree Divakar; Mateusz Dyla; Wishva Herath; Andrew P Hutchins; Ralf Jauch; Prasanna R Kolatkar; Calista Keow Leng Ng; Sun Lili; Paul Robson; Roy Teo; Lawrence W Stanton
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.
Marie V Wong; Paaventhan Palasingam; Prasanna R Kolatkar
Cloning, purification and preliminary X-ray data analysis of the human ID2 homodimer.
Yu Liang; Lawrence W Stanton; Pugalenthi Ganesan; Felicia Huimei Hong; Ralf Jauch; Sizun Jiang; Prasanna R Kolatkar
Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206.

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All Publications

2013: Irene Aksoy; Gireesh K Bogu; Jiaxuan Chen; Ushashree Divakar; Mateusz Dyla; Wishva Herath; Andrew P Hutchins; Ralf Jauch; Prasanna R Kolatkar; Calista Keow Leng Ng; Sun Lili; Paul Robson; Roy Teo; Lawrence W Stanton
Oct4 switches partnering from Sox2 to Sox17 to reinterpret the enhancer code and specify endoderm.
The EMBO journal 2013;32(7):938-53.
2012: Marie V Wong; Paaventhan Palasingam; Prasanna R Kolatkar
Cloning, purification and preliminary X-ray data analysis of the human ID2 homodimer.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 11):1354-8.
2012: Yu Liang; Lawrence W Stanton; Pugalenthi Ganesan; Felicia Huimei Hong; Ralf Jauch; Sizun Jiang; Prasanna R Kolatkar
Structural analysis and dimerization profile of the SCAN domain of the pluripotency factor Zfp206.
Nucleic acids research 2012;40(17):8721-32.
2012: Calista K L Ng; Shyam Prabhakar; Sheena Chee; Prasanna R Kolatkar; Noel X Li; Ralf Jauch
Deciphering the Sox-Oct partner code by quantitative cooperativity measurements.
Nucleic acids research 2012;40(11):4933-41.
2012: Yu Liang; Paaventhan Palasingam; Michael Rossbach; Nithya Baburajendran; Siew Hua Choo; Prasanna R Kolatkar
Crystal optimization and preliminary diffraction data analysis of the SCAN domain of Zfp206.
Acta crystallographica. Section F, Structural biology and crystallization communications 2012;68(Pt 4):443-7.
2012: Ralf Jauch; Kamesh Narasimhan; Calista K L Ng; Prasanna R Kolatkar
The crystal structure of the Sox4 HMG domain-DNA complex suggests a mechanism for positional interdependence in DNA recognition.
The Biochemical journal 2012;443(1):39-47.
2012: Marie Vivian Wong; Paaventhan Palasingam; Sizun Jiang; Prasanna R Kolatkar
A divalent ion is crucial in the structure and dominant-negative function of ID proteins, a class of helix-loop-helix transcription regulators.
PloS one 2012;7(10):e48591.
2011: Nithya Baburajendran; Ralf Jauch; Kamesh Narasimhan; Clara Yueh Zhen Tan; Prasanna R Kolatkar
Structural basis for the cooperative DNA recognition by Smad4 MH1 dimers.
Nucleic acids research 2011;39(18):8213-22.
2011: Kamesh Narasimhan; Konstantin Pervushin; Shubhadra Pillay; Li Yan; Zsolt Bikádi; Nor Rizal Bin Ahmad; Eszter Hazai; Prasanna R Kolatkar; Ralf Jauch
Identification of a polyoxometalate inhibitor of the DNA binding activity of Sox2.
ACS chemical biology 2011;6(6):573-81.
2011: Ralf Jauch; Irene Aksoy; Andrew Paul Hutchins; Calista Keow Leng Ng; Xian Feng Tian; Jiaxuan Chen; Paaventhan Palasingam; Paul Robson; Lawrence W Stanton; Prasanna R Kolatkar
Conversion of Sox17 into a pluripotency reprogramming factor by reengineering its association with Oct4 on DNA.
Stem cells (Dayton, Ohio) 2011;29(6):940-51.
2011: Ralf Jauch; Siew Hua Choo; Calista Keow Leng Ng; Prasanna R Kolatkar
Crystal structure of the dimeric Oct6 (POU3f1) POU domain bound to palindromic MORE DNA.
Proteins 2011;79(2):674-7.
2010: Ganesan Pugalenthi; Krishna Kumar Kandaswamy; PN Suganthan; Ramanathan Sowdhamini; Thomas Martinetz; Prasanna R Kolatkar
SMpred: a support vector machine approach to identify structural motifs in protein structure without using evolutionary information.
Journal of biomolecular structure & dynamics 2010;28(3):405-14.
2010: Nithya BabuRajendran; Paaventhan Palasingam; Kamesh Narasimhan; Wenjie Sun; Shyam Prabhakar; Ralf Jauch; Prasanna R Kolatkar
Structure of Smad1 MH1/DNA complex reveals distinctive rearrangements of BMP and TGF-beta effectors.
Nucleic acids research 2010;38(10):3477-88.
2009: Nithya Baburajendran; Paaventhan Palasingam; Calista Keow Leng Ng; Ralf Jauch; Prasanna R Kolatkar
Crystal optimization and preliminary diffraction data analysis of the Smad1 MH1 domain bound to a palindromic SBE DNA element.
Acta crystallographica. Section F, Structural biology and crystallization communications 2009;65(Pt 11):1105-9.
2009: Paaventhan Palasingam; Ralf Jauch; Calista Keow Leng Ng; Prasanna R Kolatkar
The structure of Sox17 bound to DNA reveals a conserved bending topology but selective protein interaction platforms.
Journal of molecular biology 2009;388(3):619-30.
2008: Calista Keow Leng Ng; Paaventhan Palasingam; Rajakannan Venkatachalam; Nithya Baburajendran; Jason Cheng; Ralf Jauch; Prasanna R Kolatkar
Purification, crystallization and preliminary X-ray diffraction analysis of the HMG domain of Sox17 in complex with DNA.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 12):1184-7.
2008: Ralf Jauch; Calista Keow Leng Ng; Kumar Singh Saikatendu; Raymond C Stevens; Prasanna R Kolatkar
Crystal structure and DNA binding of the homeodomain of the stem cell transcription factor Nanog.
Journal of molecular biology 2008;376(3):758-70.
2007: Ralf Jauch; Hock Chuan Yeo; Prasanna R Kolatkar; Neil D Clarke
Assessment of CASP7 structure predictions for template free targets.
Proteins 2007;69 Suppl 8():57-67.
2005: Palasingam Paaventhan; Chunguang Kong; Jeremiah S Joseph; Maxey C M Chung; Prasanna R Kolatkar
Structure of rhodocetin reveals noncovalently bound heterodimer interface.
Protein science : a publication of the Protein Society 2005;14(1):169-75.
2004: Jer-Ming Chia; Prasanna R Kolatkar
Implications for domain fusion protein-protein interactions based on structural information.
BMC bioinformatics 2004;5():161.
2004: Vinsensius B Vega; Yijun Ruan; Jianjun Liu; Wah Heng Lee; Chia-Lin Wei; Su Yun Se Thoe; Kin Fai Tang; Tao Zhang; Prasanna R Kolatkar; Eng Eong Ooi; Ai Ee Ling; Lawrence W Stanton; Philip M Long; Edison Liu
Mutational dynamics of the SARS coronavirus in cell culture and human populations isolated in 2003.
BMC infectious diseases 2004;4():32.
2004: Xiaolei Li; Lu Zheng; Chunguang Kong; Prasanna R Kolatkar; Maxey C M Chung
Purpureotin: a novel di-dimeric C-type lectin-like protein from Trimeresurus purpureomaculatus venom is stabilized by noncovalent interactions.
Archives of biochemistry and biophysics 2004;424(1):53-62.
2003: K Lin; Say Beng Tan; Prasanna R Kolatkar; R J Epstein
Nonrandom intragenic variations in patterns of codon bias implicate a sequential interplay between transitional genetic drift and functional amino acid selection.
Journal of molecular evolution 2003;57(5):538-45.
2003: Palasingam Paaventhan; Jeremiah S Joseph; See Voon Seow; Shai Vaday; Howard Robinson; Kaw Yan Chua; Prasanna R Kolatkar
A 1.7A structure of Fve, a member of the new fungal immunomodulatory protein family.
Journal of molecular biology 2003;332(2):461-70.
2003: Nge Cheong; S C Soon; J D A Ramos; I-Chun Kuo; Prasanna R Kolatkar; Bee Wah Lee; Kaw Yan Chua; P R Kolortkar
Lack of human IgE cross-reactivity between mite allergens Blo t 1 and Der p 1.
Allergy 2003;58(9):912-20.
2003: See Voon Seow; I-Chun Kuo; Palasingam Paaventhan; Prasanna R Kolatkar; Kaw Yan Chua
Crystallization and preliminary X-ray crystallographic studies on the fungal immunomodulatory protein Fve from the golden needle mushroom (Flammulina velutipes).
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 8):1487-9.
2003: Bing Zhao; Adrian Png; Ee Chee Ren; Prasanna R Kolatkar; Venkatarajan Subramanian Mathura; Meena Kishore Sakharkar; Pandjassarame Kangueane
Compression of functional space in HLA-A sequence diversity.
Human immunology 2003;64(7):718-28.
2003: Palasingam Paaventhan; Jeremiah S Joseph; Selvanayagam Nirthanan; Ganapathy Rajaseger; Ponnampalam Gopalakrishnakone; Manjunatha R Kini; Prasanna R Kolatkar
Crystallization and preliminary X-ray analysis of candoxin, a novel reversible neurotoxin from the Malayan krait Bungarus candidus.
Acta crystallographica. Section D, Biological crystallography 2003;59(Pt 3):584-6.
2002: Kui Lin; Yuyu Kuang; Jeremiah S Joseph; Prasanna R Kolatkar
Conserved codon composition of ribosomal protein coding genes in Escherichia coli, Mycobacterium tuberculosis and Saccharomyces cerevisiae: lessons from supervised machine learning in functional genomics.
Nucleic acids research 2002;30(11):2599-607.
2002: Yek-Cheng Ong; Prasanna R Kolatkar; Eu Leong Yong
Androgen receptor mutations causing human androgen insensitivity syndromes show a key role of residue M807 in Helix 8-Helix 10 interactions and in receptor ligand-binding domain stability.
Molecular human reproduction 2002;8(2):101-8.
2001: R Wang; Chunguang Kong; Prasanna R Kolatkar; Maxey C M Chung
A novel dimer of a C-type lectin-like heterodimer from the venom of Calloselasma rhodostoma (Malayan pit viper).
FEBS letters 2001;508(3):447-53.
2001: Pandjassarame Kangueane; Meena Kishore Sakharkar; Prasanna R Kolatkar; Ee Chee Ren
Towards the MHC-peptide combinatorics.
Human immunology 2001;62(5):539-56.
2000: Meena Kishore Sakharkar; Pandjassarame Kangueane; T W Woon; Tin Wee Tan; Prasanna R Kolatkar; M Long; Sandro J de Souza
IE-Kb: intron exon knowledge base.
Bioinformatics (Oxford, England) 2000;16(12):1151-2.
2000: Peter Kuhn; A M Deacon; S Comoso; Ganapathy Rajaseger; R Manjunatha Kini; I Usón; Prasanna R Kolatkar
The atomic resolution structure of bucandin, a novel toxin isolated from the Malayan krait, determined by direct methods.
Acta crystallographica. Section D, Biological crystallography 2000;56(Pt 11):1401-7.
2000: Pandjassarame Kangueane; Meena Kishore Sakharkar; K S Lim; H Hao; K Lin; Ren Ee Chee; Prasanna R Kolatkar
Knowledge-based grouping of modeled HLA peptide complexes.
Human immunology 2000;61(5):460-6.
2000: Ee Chee Ren; Pandjassarame Kangueane; Prasanna R Kolatkar; M T Lin; L H Tseng; J A Hansen
Molecular modeling of the minor histocompatibility antigen HA-1 peptides binding to HLA-A alleles.
Tissue antigens 2000;55(1):24-30.
1999: W S Yew; Prasanna R Kolatkar; P Kuhn; Hoon Eng Khoo
Crystallization and preliminary crystallographic study of stonustoxin, a protein lethal factor isolated from the stonefish (Synanceja horrida) venom.
Journal of structural biology 1999;128(2):216-8.
1999: W Salamonsen; K Y Mok; Prasanna R Kolatkar; Subramanian Subbiah
BioJAKE: a tool for the creation, visualization and manipulation of metabolic pathways.
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1999;():392-400.
1998: Prasanna R Kolatkar; Meena Kishore Sakharkar; T C Roderic; B K Kiong; Limsoon Wong; Tin Wee Tan; Subramanian Subbiah
Integration of bioInformatics tools at the National University of Singapore (NUS).
Studies in health technology and informatics 1998;52 Pt 1():356-60.
1998: Prasanna R Kolatkar; Meena Kishore Sakharkar; C R Tse; B K Kiong; Limsoon Wong; Tin Wee Tan; Subramanian Subbiah
Development of software tools at BioInformatics Centre (BIC) at the National University of Singapore (NUS).
Pacific Symposium on Biocomputing. Pacific Symposium on Biocomputing 1998;():735-46.