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Thomas Kolbe

Research Profile

Chemicals & Drugs

Living Beings

Anatomy

Macrophages

Physiology

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Publications

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Monica Musteanu; Josef Martin Penninger; Helmut Popper; Thomas Rülicke; Daniel Schramek; Dagmar Stoiber; Jasmin Svinka; Rainer Zenz; Beatrice Grabner; Thomas Hoffmann; Hans-Peter Kantner; Lukas Kenner; Thomas Kolbe; Richard Moriggl; Mathias Müller; Leander Blaas; Emilio Casanova; Robert Eferl
A mouse model to identify cooperating signaling pathways in cancer.
Barbara Wallner; Thomas Rülicke; Raimund M Vielnascher; Thomas Decker; Marina Karaghiosoff; Elisabeth Kernbauer; Thomas Kolbe; Nicole R Leitner; Mathias Müller
Generation of mice with a conditional Stat1 null allele.
Michaela Prchal-Murphy; Thomas Rülicke; Christian Semper; Birgit Strobl; Ingeborg Teppner-Klymiuk; Barbara Wallner; Simone Müller; Andras Dinnyés; Christian Gausterer; Marina Karaghiosoff; Julianna Kobolak; Thomas Kolbe; Caroline Lassnig; Nicole R Leitner; Mathias Müller
TYK2 kinase activity is required for functional type I interferon responses in vivo.

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All Publications

2012: Monica Musteanu; Josef Martin Penninger; Helmut Popper; Thomas Rülicke; Daniel Schramek; Dagmar Stoiber; Jasmin Svinka; Rainer Zenz; Beatrice Grabner; Thomas Hoffmann; Hans-Peter Kantner; Lukas Kenner; Thomas Kolbe; Richard Moriggl; Mathias Müller; Leander Blaas; Emilio Casanova; Robert Eferl
A mouse model to identify cooperating signaling pathways in cancer.
Nature methods 2012;9(9):897-900.
2012: Barbara Wallner; Thomas Rülicke; Raimund M Vielnascher; Thomas Decker; Marina Karaghiosoff; Elisabeth Kernbauer; Thomas Kolbe; Nicole R Leitner; Mathias Müller
Generation of mice with a conditional Stat1 null allele.
Transgenic research 2012;21(1):217-24.
2012: Michaela Prchal-Murphy; Thomas Rülicke; Christian Semper; Birgit Strobl; Ingeborg Teppner-Klymiuk; Barbara Wallner; Simone Müller; Andras Dinnyés; Christian Gausterer; Marina Karaghiosoff; Julianna Kobolak; Thomas Kolbe; Caroline Lassnig; Nicole R Leitner; Mathias Müller
TYK2 kinase activity is required for functional type I interferon responses in vivo.
PloS one 2012;7(6):e39141.
2012: Thomas Kolbe; Rupert Palme; Chadi Touma; Thomas Rülicke
Repeated use of surrogate mothers for embryo transfer in the mouse.
Biology of reproduction 2012;86(1):1-6.
2011: Christine Schneckenleithner; Dagmar Stoiber; Kay-Uwe Wagner; Zsuzsanna Bago-Horvath; Thomas Decker; Helmut Dolznig; Dontscho Kerjaschki; Thomas Kolbe; Karoline Kollmann; Mathias Müller; Nina Neugebauer; Veronika Sexl
Putting the brakes on mammary tumorigenesis: loss of STAT1 predisposes to intraepithelial neoplasias.
Oncotarget 2011;2(12):1043-54.
2011: Tom Grunert; Thomas Kolbe; Dagmar Kratky; Nicole R Leitner; Martina Marchetti-Deschmann; Ingrid Miller; Mathias Müller; Marta Radwan; Günter Allmaier; Manfred Gemeiner; Claus Vogl; Barbara Wallner; Birgit Strobl
A comparative proteome analysis links tyrosine kinase 2 (Tyk2) to the regulation of cellular glucose and lipid metabolism in response to poly(I:C).
Journal of proteomics 2011;74(12):2866-80.
2010: Elvira Grabensteiner; Ivana Bilic; Thomas Kolbe; Michael Hess
Molecular analysis of clonal trichomonad isolates indicate the existence of heterogenic species present in different birds and within the same host.
Veterinary parasitology 2010;172(1-2):53-64.
2010: Thomas Kolbe; Christian Hollinsky; Ingrid Walter; Anja Joachim; Thomas Rülicke
Influence of a new self-gripping hernia mesh on male fertility in a rat model.
Surgical endoscopy 2010;24(2):455-61.
2009: Andreas Pilz; Wolfgang Kratky; Silvia Stockinger; Olivia Simma; Ulrich Kalinke; Karen Lingnau; Alexander von Gabain; Dagmar Stoiber; Veronika Sexl; Thomas Kolbe; Thomas Rülicke; Mathias Müller; Thomas Decker
Dendritic cells require STAT-1 phosphorylated at its transactivating domain for the induction of peptide-specific CTL.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(4):2286-93.
2008: Andrea Schneider; Ursula Reichart; Wilhelm Gerner; Thomas Kolbe; Armin Saalmüller; Mathias Müller
Selective contribution of Tyk2 to cell activation by lipopolysaccharide.
FEBS letters 2008;582(25-26):3681-6.
2008: Marta Radwan; Ingrid Miller; Tom Grunert; Martina Marchetti-Deschmann; Claus Vogl; Niaobh O'Donoghue; Michael J Dunn; Thomas Kolbe; Günter Allmaier; Manfred Gemeiner; Mathias Müller; Birgit Strobl
The impact of tyrosine kinase 2 (Tyk2) on the proteome of murine macrophages and their response to lipopolysaccharide (LPS).
Proteomics 2008;8(17):3469-85.
2008: Giuseppina Costantino; Monika Egerbacher; Thomas Kolbe; Marina Karaghiosoff; Birgit Strobl; Claus Vogl; Magdalena Helmreich; Mathias Müller
Tyk2 and signal transducer and activator of transcription 1 contribute to intestinal I/R injury.
Shock (Augusta, Ga.) 2008;29(2):238-44.
2007: Thomas Kolbe; W Lechner
Influence of hernioplastic implants on male fertility in rats.
Journal of biomedical materials research. Part B, Applied biomaterials 2007;81(2):435-40.
2007: Ronald Painz; Ingrid Walter; Thomas Kolbe; Doris Rigler; Claus Vogl; Ralf Steinborn; Thomas Rülicke; Magdalena Helmreich; Marina Karaghiosoff; Mathias Müller
Organ-specific and differential requirement of TYK2 and IFNAR1 for LPS-induced iNOS expression in vivo.
Immunobiology 2007;212(9-10):863-75.
2006: Michael Hess; Thomas Kolbe; Elvira Grabensteiner; Heinrich Prosl
Clonal cultures of Histomonas meleagridis, Tetratrichomonas gallinarum and a Blastocystis sp. established through micromanipulation.
Parasitology 2006;133(Pt 5):547-54.
2006: Ines Sauer; Barbara Schaljo; Claus Vogl; Irene Gattermeier; Thomas Kolbe; Mathias Müller; Perry Blackshear; Pavel Kovarik
Interferons limit inflammatory responses by induction of tristetraprolin.
Blood 2006;107(12):4790-7.
2006: Nicole R Leitner; Birgit Strobl; Marion Bokor; Ronald Painz; Thomas Kolbe; Thomas Rülicke; Mathias Müller; Marina Karaghiosoff
A time- and dose-dependent STAT1 expression system.
BMC biotechnology 2006;6():48.
2005: Birgit Strobl; Ivan Bubic; Ute Bruns; Ralf Steinborn; Robert Lajko; Thomas Kolbe; Marina Karaghiosoff; Ulrich Kalinke; Stipan Jonjic; Mathias Müller
Novel functions of tyrosine kinase 2 in the antiviral defense against murine cytomegalovirus.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(6):4000-8.
2005: Caroline Lassnig; Carlos M Sanchez; Monika Egerbacher; Ingrid Walter; Susanne Majer; Thomas Kolbe; Pilar Pallares; Luis Enjuanes; Mathias Müller
Development of a transgenic mouse model susceptible to human coronavirus 229E.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(23):8275-80.
2003: Louisa Varinou; Katrin Ramsauer; Marina Karaghiosoff; Thomas Kolbe; Klaus Pfeffer; Mathias Müller; Thomas Decker
Phosphorylation of the Stat1 transactivation domain is required for full-fledged IFN-gamma-dependent innate immunity.
Immunity 2003;19(6):793-802.
2003: Marina Karaghiosoff; Ralf Steinborn; Pavel Kovarik; Gernot Kriegshäuser; Manuela Baccarini; Birgit Donabauer; Ursula Reichart; Thomas Kolbe; Christian Bogdan; Tomas Leanderson; David Levy; Thomas Decker; Mathias Müller
Central role for type I interferons and Tyk2 in lipopolysaccharide-induced endotoxin shock.
Nature immunology 2003;4(5):471-7.
2002: Silvia Stockinger; Tilo Materna; Dagmar Stoiber; Lourdes Bayr; Ralf Steinborn; Thomas Kolbe; Hermann Unger; Trinad Chakraborty; David E Levy; Mathias Müller; Thomas Decker
Production of type I IFN sensitizes macrophages to cell death induced by Listeria monocytogenes.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(11):6522-9.