FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Padmanabhan Balaram

Research Profile

Concepts & Ideas

Phenomena

Chemicals & Drugs

Genes & Molecular Sequences

Procedures

X Ray Crystallography

Physiology

Protein Folding

Co-author Network

Publications

TOP 3
Moitrayee Bhattacharyya; Konkallu Hanumae Gowd; Kallol Gupta; Padmanabhan Balaram
Rapid mass spectrometric determination of disulfide connectivity in peptides and proteins.
Rajesh Sonti; Hosahudya N Gopi; Umashankara Muddegowda; Srinivasarao Ragothama; Padmanabhan Balaram
A Designed Three-Stranded β-Sheet in an α/β Hybrid Peptide.
Krishnayan Basuroy; Bhimareddy Dinesh; Narayanaswamy Shamala; Padmanabhan Balaram
Promotion of folding in hybrid peptides through unconstrained γ residues: structural characterization of helices in (αγγ)n and (αγα)n sequences.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Padmanabhan Balaram (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Moitrayee Bhattacharyya; Konkallu Hanumae Gowd; Kallol Gupta; Padmanabhan Balaram
Rapid mass spectrometric determination of disulfide connectivity in peptides and proteins.
Molecular bioSystems 2013;9(6):1340-50.
2013: Rajesh Sonti; Hosahudya N Gopi; Umashankara Muddegowda; Srinivasarao Ragothama; Padmanabhan Balaram
A Designed Three-Stranded β-Sheet in an α/β Hybrid Peptide.
Chemistry (Weinheim an der Bergstrasse, Germany) 2013;19(19):5955-65.
2013: Krishnayan Basuroy; Bhimareddy Dinesh; Narayanaswamy Shamala; Padmanabhan Balaram
Promotion of folding in hybrid peptides through unconstrained γ residues: structural characterization of helices in (αγγ)n and (αγα)n sequences.
Angewandte Chemie (International ed. in English) 2013;52(11):3136-9.
2012: Rajesh Sonti; Srinivasarao Ragothama; Rajkishor Rai; Padmanabhan Balaram
NMR analysis of cross strand aromatic interactions in an 8 residue hairpin and a 14 residue three stranded β-sheet peptide.
The journal of physical chemistry. B 2012;116(49):14207-15.
2012: Keith K Khoo; Padmanabhan Balaram; Grzegorz Bulaj; Brad R Green; Kallol Gupta; Baldomero M Olivera; Maren Watkins; Doju Yoshikami; Min-Min Zhang; Raymond S Norton
Distinct disulfide isomers of μ-conotoxins KIIIA and KIIIB block voltage-gated sodium channels.
Biochemistry 2012;51(49):9826-35.
2012: Khyati V Pathak; Suman S Thakur; Kallol Gupta; Haresh Keharia; Padmanabhan Balaram
Lipopeptides from the banyan endophyte, Bacillus subtilis K1: mass spectrometric characterization of a library of fengycins.
Journal of the American Society for Mass Spectrometry 2012;23(10):1716-28.
2012: Krishnayan Basuroy; Bhimareddy Dinesh; Narayanaswamy Shamala; Padmanabhan Balaram
Structural characterization of backbone-expanded helices in hybrid peptides: (αγ)n and (αβ)n sequences with unconstrained β and γ homologues of L-Val.
Angewandte Chemie (International ed. in English) 2012;51(35):8736-9.
2012: Krishnayan Basuroy; Srinivasarao Raghothama; Appavu Rajagopal; Narayanaswamy Shamala; Padmanabhan Balaram
β-Turn analogues in model αβ-hybrid peptides: structural characterization of peptides containing β(2,2)Ac6c and β(3,3)Ac6c residues.
Chemistry, an Asian journal 2012;7(7):1671-8.
2012: Siddappa Chandrappa; Veldore V Harini; Srinivasarao Raghothama; Rajkishor Rai; Narayanaswamy Shamala; Rajesh Sonti; Subrayashastry Aravinda; Padmanabhan Balaram
Helix and hairpin nucleation in short peptides using centrally positioned conformationally constrained dipeptide segments.
Organic & biomolecular chemistry 2012;10(14):2815-23.
2012: Prema G Vasudev; Mousumi Banerjee; C Ramakrishnan; Padmanabhan Balaram
Asparagine and glutamine differ in their propensities to form specific side chain-backbone hydrogen bonded motifs in proteins.
Proteins 2012;80(4):991-1002.
2012: Kallol Gupta; Kozhalmannom S Krishnan; Mukesh Kumar; Krishnappa Chandrashekara; Padmanabhan Balaram
Combined electron transfer dissociation-collision-induced dissociation fragmentation in the mass spectrometric distinction of leucine, isoleucine, and hydroxyproline residues in Peptide natural products.
Journal of proteome research 2012;11(2):515-22.
2012: Appavu Rajagopal; Narayanaswamy Shamala; Subrayashastry Aravinda; Srinivasarao Raghothama; Padmanabhan Balaram
Aromatic interactions in model peptide β-hairpins: ring current effects on proton chemical shifts.
Biopolymers 2012;98(3):185-94.
2012: Subrayashastry Aravinda; Isabella L Karle; Narayanaswamy Shamala; Padmanabhan Balaram
Characterization of bent helical conformations in polymorphic forms of a designed 18-residue peptide containing a central gly-pro segment.
Biopolymers 2012;98(1):76-86.
2011: Moumita Samanta; M R N Murthy; Hemalatha Balaram; Padmanabhan Balaram
Revisiting the mechanism of the triosephosphate isomerase reaction: the role of the fully conserved glutamic acid 97 residue.
Chembiochem : a European journal of chemical biology 2011;12(12):1886-96.
2011: Mousumi Banerjee; Kallol Gupta; Hemalatha Balaram; Padmanabhan Balaram
Mass spectrometric identification of an intramolecular disulfide bond in thermally inactivated triosephosphate isomerase from a thermophilic organism Methanocaldococcus jannaschii.
Rapid communications in mass spectrometry : RCM 2011;25(14):1915-23.
2011: Upadhyayula Surya Raghavender; Appavu Rajagopal; Indranil Saha; Narayanaswamy Shamala; Bhaswati Chatterjee; Padmanabhan Balaram
Entrapment of a water wire in a hydrophobic peptide channel with an aromatic lining.
The journal of physical chemistry. B 2011;115(29):9236-43.
2011: Moumita Samanta; Mousumi Banerjee; Mathur R N Murthy; Hemalatha Balaram; Padmanabhan Balaram
Probing the role of the fully conserved Cys126 in triosephosphate isomerase by site-specific mutagenesis--distal effects on dimer stability.
The FEBS journal 2011;278(11):1932-43.
2011: Mousumi Banerjee; Hemalatha Balaram; N V Joshi; Padmanabhan Balaram
Engineered dimer interface mutants of triosephosphate isomerase: the role of inter-subunit interactions in enzyme function and stability.
Protein engineering, design & selection : PEDS 2011;24(5):463-72.
2011: Prema G Vasudev; Sunanda Chatterjee; Narayanaswamy Shamala; Padmanabhan Balaram
Structural chemistry of peptides containing backbone expanded amino acid residues: conformational features of β, γ, and hybrid peptides.
Chemical reviews 2011;111(2):657-87.
2011: Appavu Rajagopal; Narayanaswamy Shamala; Subrayashastry Aravinda; Srinivasarao Raghothama; Padmanabhan Balaram
Chain length effects on helix-hairpin distribution in short peptides with Aib-DAla and Aib-Aib segments.
Biopolymers 2011;96(6):744-56.
2010: Kallol Gupta; Mukesh Kumar; Padmanabhan Balaram
Disulfide bond assignments by mass spectrometry of native natural peptides: cysteine pairing in disulfide bonded conotoxins.
Analytical chemistry 2010;82(19):8313-9.
2010: Vijayalekshmi Sarojini; R Balaji Rao; S Ragothama; Padmanabhan Balaram
Solution conformation of a tetradecapeptide stabilized by two di-n-propyl glycine residues.
Journal of peptide science : an official publication of the European Peptide Society 2010;16(8):430-6.
2010: Upadhyayula Surya Raghavender; Subrayashastry Aravinda; Rajkishor Rai; Narayanaswamy Shamala; Padmanabhan Balaram
Peptide hairpin nucleation with the obligatory Type I' beta-turn Aib-DPro segment.
Organic & biomolecular chemistry 2010;8(14):3133-5.
2010: Upadhyayula S Raghavender; Subrayashastry Aravinda; Narayanaswamy Shamala; Padmanabhan Balaram
Hydrophobic peptide channels and encapsulated water wires.
Journal of the American Chemical Society 2010;132(3):1075-86.
2010: Padmanabhan Balaram
Hybrid polypeptides: gabapentin as a stereochemically constrained γ-amino acid residue.
Biopolymers 2010;94(6):733-41.
2010: Srinivasarao Raghothama; Subrayashastry Aravinda; Narayanaswamy Shamala; Padmanabhan Balaram
Helical conformations of hexapeptides containing N-terminus diproline segments.
Biopolymers 2010;94(3):360-70.
2009: Suman S Thakur; Rappal S Ranganayaki; Kallol Gupta; Padmanabhan Balaram
Identification of alpha- and beta-hydroxy acid containing cyclodepsipeptides in natural peptide mixtures using negative ion mass spectrometry.
Journal of the American Society for Mass Spectrometry 2009;20(12):2221-8.
2009: Upadhyayula S Raghavender; Subrayashastry Aravinda; Narayanaswamy Shamala; Rajkishor Rai; Padmanabhan Balaram
Characterization of water wires inside hydrophobic tubular peptide structures.
Journal of the American Chemical Society 2009;131(42):15130-2.
2009: Prema G Vasudev; Sunanda Chatterjee; Narayanaswamy Shamala; Padmanabhan Balaram
Gabapentin: a stereochemically constrained gamma amino acid residue in hybrid peptide design.
Accounts of chemical research 2009;42(10):1628-39.
2009: Pananghat Gayathri; Mousumi Banerjee; A Vijayalakshmi; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Biochemical and structural characterization of residue 96 mutants of Plasmodium falciparum triosephosphate isomerase: active-site loop conformation, hydration and identification of a dimer-interface ligand-binding site.
Acta crystallographica. Section D, Biological crystallography 2009;65(Pt 8):847-57.
2009: Mousumi Banerjee; Hemalatha Balaram; Padmanabhan Balaram
Structural effects of a dimer interface mutation on catalytic activity of triosephosphate isomerase. The role of conserved residues and complementary mutations.
The FEBS journal 2009;276(15):4169-83.
2009: Suman S Thakur; P D Deepalakshmi; Pananghat Gayathri; Mousumi Banerjee; M R N Murthy; Padmanabhan Balaram
Detection of the protein dimers, multiple monomeric states and hydrated forms of Plasmodium falciparum triosephosphate isomerase in the gas phase.
Protein engineering, design & selection : PEDS 2009;22(5):289-304.
2009: Suman S Thakur; Padmanabhan Balaram
Characterization of alkali induced formation of lanthionine, trisulfides, and tetrasulfides from peptide disulfides using negative ion mass spectrometry.
Journal of the American Society for Mass Spectrometry 2009;20(5):783-91.
2009: Sunanda Chatterjee; Prema G Vasudev; Srinivasarao Raghothama; Chandrasekharan Ramakrishnan; Narayanaswamy Shamala; Padmanabhan Balaram
Expanding the peptide beta-turn in alphagamma hybrid sequences: 12 atom hydrogen bonded helical and hairpin turns.
Journal of the American Chemical Society 2009;131(16):5956-65.
2009: Prema G Vasudev; Sunanda Chatterjee; C Ramakrishnan; Narayanaswamy Shamala; Padmanabhan Balaram
Conformational choices for the stereochemically constrained gamma-amino acid residue gabapentin: theoretical studies and correlation with experimental results.
Biopolymers 2009;92(5):426-35.
2009: Srinivasarao Raghothama; Upadhyayula Surya Raghavender; Subrayashastry Aravinda; Narayanaswamy Shamala; Padmanabhan Balaram
Conformations of heterochiral and homochiral proline-pseudoproline segments in peptides: context dependent cis-trans peptide bond isomerization.
Biopolymers 2009;92(5):405-16.
2009: Prema G Vasudev; Subrayashastry Aravinda; Kuppanna Ananda; Shettykere Dayananda Veena; Kuppuswamy Nagarajan; Narayanaswamy Shamala; Padmanabhan Balaram
Crystal structures of a new polymorphic form of gabapentin monohydrate and the e and z isomers of 4-tertiarybutylgabapentin.
Chemical biology & drug design 2009;73(1):83-96.
2008: Sunanda Chatterjee; Prema G Vasudev; Kuppanna Ananda; Srinivasarao Raghothama; Narayanaswamy Shamala; Padmanabhan Balaram
Multiple conformational states in crystals and in solution in alphagamma hybrid peptides. Fragility of the C12 helix in short sequences.
The Journal of organic chemistry 2008;73(17):6595-606.
2008: Subrayashastry Aravinda; Narayanaswamy Shamala; Padmanabhan Balaram
Aib residues in peptaibiotics and synthetic sequences: analysis of nonhelical conformations.
Chemistry & biodiversity 2008;5(7):1238-62.
2008: Konkallu Hanumae Gowd; Kalyan Kumar Dewan; Prathima Iengar; Kozhalmannom S Krishnan; Padmanabhan Balaram
Probing peptide libraries from Conus achatinus using mass spectrometry and cDNA sequencing: identification of delta and omega-conotoxins.
Journal of mass spectrometry : JMS 2008;43(6):791-805.
2008: Raghurama P Hegde; Subrayashastry Aravinda; Rajkishor Rai; R Kaul; Sarojini Vijayalakshmi; R Balaji Rao; Narayanaswamy Shamala; Padmanabhan Balaram
Conformation of di-n-propylglycine residues (Dpg) in peptides: crystal structures of a type I' beta-turn forming tetrapeptide and an alpha-helical tetradecapeptide.
Journal of peptide science : an official publication of the European Peptide Society 2008;14(5):648-59.
2008: Suman S Thakur; Padmanabhan Balaram
Fragmentation of peptide disulfides under conditions of negative ion mass spectrometry: studies of oxidized glutathione and contryphan.
Journal of the American Society for Mass Spectrometry 2008;19(3):358-66.
2008: Prema G Vasudev; Narayanaswamy Shamala; Padmanabhan Balaram
Nucleation, growth, and form in crystals of peptide helices.
The journal of physical chemistry. B 2008;112(4):1308-14.
2008: Sunanda Chatterjee; Prema G Vasudev; Srinivasarao Raghothama; Narayanaswamy Shamala; Padmanabhan Balaram
Solid state and solution conformations of a hybrid alphagammaalphaalphagammaalpha hexapeptide. Characterization of a backbone expanded analog of the alpha-polypeptide 3(10)-helix.
Biopolymers 2008;90(6):759-71.
2008: Prema G Vasudev; Sunanda Chatterjee; Kuppanna Ananda; Narayanaswamy Shamala; Padmanabhan Balaram
Hybrid alphagamma polypeptides: structural characterization of a C12/C10 helix with alternating hydrogen-bond polarity.
Angewandte Chemie (International ed. in English) 2008;47(34):6430-2.
2008: Bhaswati Chatterjee; Indranil Saha; Srinivasarao Raghothama; Subrayashastry Aravinda; Rajkishor Rai; Narayanaswamy Shamala; Padmanabhan Balaram
Designed peptides with homochiral and heterochiral diproline templates as conformational constraints.
Chemistry (Weinheim an der Bergstrasse, Germany) 2008;14(20):6192-204.
2008: Indranil Saha; Bhaswati Chatterjee; Narayanaswamy Shamala; Padmanabhan Balaram
Crystal structures of peptide enantiomers and racemates: probing conformational diversity in heterochiral Pro-Pro sequences.
Biopolymers 2008;90(4):537-43.
2008: Prema G Vasudev; Rajkishor Rai; Narayanaswamy Shamala; Padmanabhan Balaram
Conformations of beta-amino acid residues in peptides: X-ray diffraction studies of peptides containing the achiral residue 1-aminocyclohexaneacetic acid, beta3,3Ac6c.
Biopolymers 2008;90(2):138-50.
2008: Y K Saikumari; Padmanabhan Balaram
An internally quenched fluorescent substrate for collagenase.
Biopolymers 2008;90(2):131-7.
2008: Amit Kumar Mandal; Shveta Bisht; Vijay S Bhat; Patnam Rajagopalan Krishnaswamy; Padmanabhan Balaram
Electrospray mass spectrometric characterization of hemoglobin Q (Hb Q-India) and a double mutant hemoglobin S/D in clinical samples.
Clinical biochemistry 2008;41(1-2):75-81.
2007: Amit Kumar Mandal; Padmanabhan Balaram
Mass spectrometric identification of pyroglutamic acid in peptides following selective hydrolysis.
Analytical biochemistry 2007;370(1):118-20.
2007: Amit Kumar Mandal; Murali Woodi; Varun Sood; Patnam Rajagopalan Krishnaswamy; Anjali Rao; Sudarshan Ballal; Padmanabhan Balaram
Quantitation and characterization of glutathionyl haemoglobin as an oxidative stress marker in chronic renal failure by mass spectrometry.
Clinical biochemistry 2007;40(13-14):986-94.
2007: Konkallu Hanumae Gowd; Kozhalmannom S Krishnan; Padmanabhan Balaram
Identification of Conus amadis disulfide isomerase: minimum sequence length of peptide fragments necessary for protein annotation.
Molecular bioSystems 2007;3(8):554-66.
2007: Amit Kumar Mandal; Santhana Ramasamy; Varatharajan Sabareesh; Matthew E Openshaw; Kozhalmannom S Krishnan; Padmanabhan Balaram
Sequencing of T-superfamily conotoxins from Conus virgo: pyroglutamic acid identification and disulfide arrangement by MALDI mass spectrometry.
Journal of the American Society for Mass Spectrometry 2007;18(8):1396-404.
2007: Varatharajan Sabareesh; R S Ranganayaki; Srinivasarao Raghothama; M P Bopanna; Hemalatha Balaram; M C Srinivasan; Padmanabhan Balaram
Identification and characterization of a library of microheterogeneous cyclohexadepsipeptides from the fungus Isaria.
Journal of natural products 2007;70(5):715-29.
2007: Prema G Vasudev; Kuppanna Ananda; Sunanda Chatterjee; Subrayashastry Aravinda; Narayanaswamy Shamala; Padmanabhan Balaram
Hybrid peptide design. Hydrogen bonded conformations in peptides containing the stereochemically constrained gamma-amino acid residue, gabapentin.
Journal of the American Chemical Society 2007;129(13):4039-48.
2007: Pananghat Gayathri; Mousumi Banerjee; A Vijayalakshmi; Shamina Azeez; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Structure of triosephosphate isomerase (TIM) from Methanocaldococcus jannaschii.
Acta crystallographica. Section D, Biological crystallography 2007;63(Pt 2):206-20.
2007: Suman S Thakur; Padmanabhan Balaram
Rapid mass spectral identification of contryphans. Detection of characteristic peptide ions by fragmentation of intact disulfide-bonded peptides in crude venom.
Rapid communications in mass spectrometry : RCM 2007;21(21):3420-6.
2007: Rajkishor Rai; Prema G Vasudev; Kuppanna Ananda; Srinivasarao Raghothama; Narayanaswamy Shamala; Isabella L Karle; Padmanabhan Balaram
Hybrid peptides: expanding the beta turn in peptide hairpins by the insertion of beta-, gamma-, and delta-residues.
Chemistry (Weinheim an der Bergstrasse, Germany) 2007;13(20):5917-26.
2007: Rajkishor Rai; Srinivasarao Raghothama; Rajagopalan Sridharan; Padmanabhan Balaram
Tuning the beta-turn segment in designed peptide beta-hairpins: construction of a stable type I' beta-turn nucleus and hairpin-helix transition promoting segments.
Biopolymers 2007;88(3):350-61.
2007: Radhakrishnan Mahalakshmi; Anindita Sengupta; Srinivasarao Raghothama; Narayanaswamy Shamala; Padmanabhan Balaram
Tryptophan rich peptides: influence of indole rings on backbone conformation.
Biopolymers 2007;88(1):36-54.
2006: Sudarslal Sadasivan Nair; Carol L Nilsson; Mark R Emmett; Tanner M Schaub; Konkallu Hanumae Gowd; Suman S Thakur; Kozhalmannom S Krishnan; Padmanabhan Balaram; Alan G Marshall
De novo sequencing and disulfide mapping of a bromotryptophan-containing conotoxin by Fourier transform ion cyclotron resonance mass spectrometry.
Analytical chemistry 2006;78(23):8082-8.
2006: Anindita Sengupta; Subrayashastry Aravinda; Narayanaswamy Shamala; K Muruga Poopathi Raja; Padmanabhan Balaram
Structural studies of model peptides containing beta-, gamma- and delta-amino acids.
Organic & biomolecular chemistry 2006;4(22):4214-22.
2006: Varatharajan Sabareesh; Konkallu Hanumae Gowd; Palanisamy Ramasamy; Sadasivannair Sudarslal; Kozhalmannom S Krishnan; Sujit K Sikdar; Padmanabhan Balaram
Characterization of contryphans from Conus loroisii and Conus amadis that target calcium channels.
Peptides 2006;27(11):2647-54.
2006: Rajkishor Rai; Subrayashastry Aravinda; Kanagarajadurai karuppiah; Srinivasarao Raghothama; Narayanaswamy Shamala; Padmanabhan Balaram
Diproline templates as folding nuclei in designed peptides. Conformational analysis of synthetic peptide helices containing amino terminal Pro-Pro segments.
Journal of the American Chemical Society 2006;128(24):7916-28.
2006: Rituparna S Roy; Hosahudya N Gopi; Srinivasarao Raghothama; Isabella L Karle; Padmanabhan Balaram
Hybrid peptide hairpins containing alpha- and omega-amino acids: conformational analysis of decapeptides with unsubstituted beta-, gamma-, and delta-residues at positions 3 and 8.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(12):3295-302.
2006: Anindita Sengupta; Rituparna S Roy; Varatharajan Sabareesh; Narayanaswamy Shamala; Padmanabhan Balaram
Aggregation modes in sheets formed by protected beta-amino acids and beta-peptides.
Organic & biomolecular chemistry 2006;4(6):1166-73.
2006: Prathima Iengar; N V Joshi; Padmanabhan Balaram
Conformational and sequence signatures in beta helix proteins.
Structure (London, England : 1993) 2006;14(3):529-42.
2006: Rajkishor Rai; Srinivasarao Raghothama; Padmanabhan Balaram
Design of a peptide hairpin containing a central three-residue loop.
Journal of the American Chemical Society 2006;128(8):2675-81.
2006: Radhakrishnan Mahalakshmi; Srinivasarao Raghothama; Padmanabhan Balaram
NMR analysis of aromatic interactions in designed peptide beta-hairpins.
Journal of the American Chemical Society 2006;128(4):1125-38.
2006: Radhakrishnan Mahalakshmi; Padmanabhan Balaram
Non-protein amino acids in the design of secondary structure scaffolds.
Methods in molecular biology (Clifton, N.J.) 2006;340():71-94.
2006: Yegnisettipalli K Saikumari; Gudihal Ravindra; Padmanabhan Balaram
Structure formation in short designed peptides probed by proteolytic cleavage.
Protein and peptide letters 2006;13(5):471-6.
2006: Varatharajan Sabareesh; Padmanabhan Balaram
Tandem electrospray mass spectrometric studies of proton and sodium ion adducts of neutral peptides with modified N- and C-termini: synthetic model peptides and microheterogeneous peptaibol antibiotics.
Rapid communications in mass spectrometry : RCM 2006;20(4):618-28.
2005: Radhakrishnan Mahalakshmi; Ganesh Shanmugam; Prasad L Polavarapu; Padmanabhan Balaram
Circular dichroism of designed peptide helices and beta-hairpins: analysis of Trp- and Tyr-rich peptides.
Chembiochem : a European journal of chemical biology 2005;6(12):2152-8.
2005: Kuppanna Ananda; Prema G Vasudev; Anindita Sengupta; K Muruga Poopathi Raja; Narayanaswamy Shamala; Padmanabhan Balaram
Polypeptide helices in hybrid peptide sequences.
Journal of the American Chemical Society 2005;127(47):16668-74.
2005: Konkallu Hanumae Gowd; Varatharajan Sabareesh; Sadasivannair Sudarslal; Prathima Iengar; Benjamin Franklin; Antony Fernando; Kalyan Dewan; Mani Ramaswami; Siddhartha P Sarma; Sujit K Sikdar; Padmanabhan Balaram; Kozhalmannom S Krishnan
Novel peptides of therapeutic promise from Indian Conidae.
Annals of the New York Academy of Sciences 2005;1056():462-73.
2005: Radhakrishnan Mahalakshmi; Anindita Sengupta; Srinivasarao Raghothama; Narayanaswamy Shamala; Padmanabhan Balaram
Tryptophan-containing peptide helices: interactions involving the indole side chain.
The journal of peptide research : official journal of the American Peptide Society 2005;66(5):277-96.
2005: Rangasamy Sampathkumar; Muthuswamy Balasubramanyam; Sadasivannair Sudarslal; Mohan Rema; Viswanthan Mohan; Padmanabhan Balaram
Increased glutathionylated hemoglobin (HbSSG) in type 2 diabetes subjects with microangiopathy.
Clinical biochemistry 2005;38(10):892-9.
2005: Prema G Vasudev; Narayanaswamy Shamala; Kuppanna Ananda; Padmanabhan Balaram
C9 helices and ribbons in gamma-peptides: crystal structures of gabapentin oligomers.
Angewandte Chemie (International ed. in English) 2005;44(31):4972-5.
2005: Veldore Vidya Harini; Subrayashastry Aravinda; Rajkishor Rai; Narayanaswamy Shamala; Padmanabhan Balaram
Molecular conformation and packing of peptide beta hairpins in the solid state: structures of two synthetic octapeptides containing 1-aminocycloalkane-1-carboxylic acid residues at the i+2 position of the beta turn.
Chemistry (Weinheim an der Bergstrasse, Germany) 2005;11(12):3609-20.
2005: Siddhartha P Sarma; G Senthil Kumar; Sadasivannair Sudarslal; Prathima Iengar; Palanisamy Ramasamy; Sujit K Sikdar; Kozhalmannom S Krishnan; Padmanabhan Balaram
Solution structure of delta-Am2766: a highly hydrophobic delta-conotoxin from Conus amadis that inhibits inactivation of neuronal voltage-gated sodium channels.
Chemistry & biodiversity 2005;2(4):535-56.
2005: Arumugam Sri Ranjini; Puspendu K Das; Padmanabhan Balaram
Binding constant measurement by hyper-Rayleigh scattering: bilirubin-human serum albumin binding as a case study.
The journal of physical chemistry. B 2005;109(12):5950-3.
2005: Rituparna S Roy; Hosahudya N Gopi; Srinivasarao Raghothama; Richard D Gilardi; Isabella L Karle; Padmanabhan Balaram
Peptide hairpins with strand segments containing alpha- and beta-amino acid residues: cross-strand aromatic interactions of facing Phe residues.
Biopolymers 2005;80(6):787-99.
2005: Anindita Sengupta; Radhakrishnan Mahalakshmi; Narayanaswamy Shamala; Padmanabhan Balaram
Aromatic interactions in tryptophan-containing peptides: crystal structures of model tryptophan peptides and phenylalanine analogs.
The journal of peptide research : official journal of the American Peptide Society 2005;65(1):113-29.
2004: Subrayashastry Aravinda; Saumen Datta; Narayanaswamy Shamala; Padmanabhan Balaram
Hydrogen-bond lengths in polypeptide helices: no evidence for short hydrogen bonds.
Angewandte Chemie (International ed. in English) 2004;43(48):6728-31.
2004: Rituparna S Roy; Isabella L Karle; Srinivasarao Raghothama; Padmanabhan Balaram
Alpha,beta hybrid peptides: a polypeptide helix with a central segment containing two consecutive beta-amino acid residues.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(47):16478-82.
2004: Kandiah Eaazhisai; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Structures of unliganded and inhibitor complexes of W168F, a Loop6 hinge mutant of Plasmodium falciparum triosephosphate isomerase: observation of an intermediate position of loop6.
Journal of molecular biology 2004;343(3):671-84.
2004: Sadasivannair Sudarslal; Govindaswamy Singaravadivelan; Palanisamy Ramasamy; Kuppanna Ananda; Siddhartha P Sarma; Sujit K Sikdar; Kozhalmannom S Krishnan; Padmanabhan Balaram
A novel 13 residue acyclic peptide from the marine snail, Conus monile, targets potassium channels.
Biochemical and biophysical research communications 2004;317(3):682-8.
2004: Gudihal Ravindra; Rappal S Ranganayaki; Srinivasarao Raghothama; Mandayam C Srinivasan; Richard D Gilardi; Isabella L Karle; Padmanabhan Balaram
Two novel hexadepsipeptides with several modified amino acid residues isolated from the fungus Isaria.
Chemistry & biodiversity 2004;1(3):489-504.
2004: Saumen Datta; R N S Rathore; S Vijayalakshmi; Prema G Vasudev; R Balaji Rao; Padmanabhan Balaram; Narayanaswamy Shamala
Peptide helices with pendant cycloalkane rings. Characterization of conformations of 1-aminocyclooctane-1-carboxylic acid (Ac8c) residues in peptides.
Journal of peptide science : an official publication of the European Peptide Society 2004;10(3):160-72.
2004: Rituparna S Roy; Padmanabhan Balaram
Conformational properties of hybrid peptides containing alpha- and omega-amino acids.
The journal of peptide research : official journal of the American Peptide Society 2004;63(3):279-89.
2004: Subrayashastry Aravinda; Veldore Vidya Harini; Narayanaswamy Shamala; Chittaranjan Das; Padmanabhan Balaram
Structure and assembly of designed beta-hairpin peptides in crystals as models for beta-sheet aggregation.
Biochemistry 2004;43(7):1832-46.
2004: Isabella L Karle; S Prasad; Padmanabhan Balaram
A combined extended and helical backbone for Boc-(Ala-Leu-Ac7c-)2-OMe.
The journal of peptide research : official journal of the American Peptide Society 2004;63(2):175-80.
2003: Sampathkumar Parthasarathy; Kandiah Eaazhisai; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Structure of Plasmodium falciparum triose-phosphate isomerase-2-phosphoglycerate complex at 1.1-A resolution.
The Journal of biological chemistry 2003;278(52):52461-70.
2003: Subrayashastry Aravinda; Narayanaswamy Shamala; Abhishek Bandyopadhyay; Padmanabhan Balaram
Probing the role of the C-H...O hydrogen bond stabilized polypeptide chain reversal at the C-terminus of designed peptide helices. Structural characterization of three decapeptides.
Journal of the American Chemical Society 2003;125(49):15065-75.
2003: Isabella L Karle; Hosahudya N Gopi; Padmanabhan Balaram
Crystal structure of a hydrophobic 19-residue peptide helix containing three centrally located D amino acids.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(24):13946-51.
2003: Sadasivannair Sudarslal; Sriparna Majumdar; Palanisamy Ramasamy; Ritu Dhawan; Prajna P Pal; Mani Ramaswami; Anil K Lala; Sujit K Sikdar; Siddhartha P Sarma; Kozhalmannom S Krishnan; Padmanabhan Balaram
Sodium channel modulating activity in a delta-conotoxin from an Indian marine snail.
FEBS letters 2003;553(1-2):209-12.
2003: Subrayashastry Aravinda; Kuppanna Ananda; Narayanaswamy Shamala; Padmanabhan Balaram
Alpha-gamma hybrid peptides that contain the conformationally constrained gabapentin residue: characterization of mimetics of chain reversals.
Chemistry (Weinheim an der Bergstrasse, Germany) 2003;9(19):4789-95.
2003: Priyaranjan Pattanaik; Bimba Jain; Gudihal Ravindra; Hosahudya N Gopi; Prajna P Pal; Hemalatha Balaram; Padmanabhan Balaram
Stage-specific profiling of Plasmodium falciparum proteases using an internally quenched multispecificity protease substrate.
Biochemical and biophysical research communications 2003;309(4):974-9.
2003: Subrayashastry Aravinda; Narayanaswamy Shamala; Chittaranjan Das; Arumugam Sriranjini; Isabella L Karle; Padmanabhan Balaram
Aromatic-aromatic interactions in crystal structures of helical peptide scaffolds containing projecting phenylalanine residues.
Journal of the American Chemical Society 2003;125(18):5308-15.
2003: S Kumar Singh; M Madan Babu; Padmanabhan Balaram
Registering alpha-helices and beta-strands using backbone C-H...O interactions.
Proteins 2003;51(2):167-71.
2003: Priyaranjan Pattanaik; Gudihal Ravindra; Chandana Sengupta; Kapil Maithal; Padmanabhan Balaram; Hemalatha Balaram
Unusual fluorescence of W168 in Plasmodium falciparum triosephosphate isomerase, probed by single-tryptophan mutants.
European journal of biochemistry / FEBS 2003;270(4):745-56.
2003: Hosahudya N Gopi; Gudihal Ravindra; Prajna P Pal; Priyaranjan Pattanaik; Hemalatha Balaram; Padmanabhan Balaram
Proteolytic stability of beta-peptide bonds probed using quenched fluorescent substrates incorporating a hemoglobin cleavage site.
FEBS letters 2003;535(1-3):175-8.
2002: Sampathkumar Parthasarathy; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Structures of Plasmodium falciparum triosephosphate isomerase complexed to substrate analogues: observation of the catalytic loop in the open conformation in the ligand-bound state.
Acta crystallographica. Section D, Biological crystallography 2002;58(Pt 12):1992-2000.
2002: Sampathkumar Parthasarathy; Gudihal Ravindra; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Structure of the Plasmodium falciparum triosephosphate isomerase-phosphoglycolate complex in two crystal forms: characterization of catalytic loop open and closed conformations in the ligand-bound state.
Biochemistry 2002;41(44):13178-88.
2002: R Sudha; M Panda; J Chandrasekhar; Padmanabhan Balaram
Structural effects on the formation of proton and alkali metal ion adducts of apolar, neutral peptides: electrospray ionization mass spectrometry and Ab initio theoretical studies.
Chemistry (Weinheim an der Bergstrasse, Germany) 2002;8(21):4980-91.
2002: Subrayashastry Aravinda; Narayanaswamy Shamala; Shrilakshmi Desiraju; Padmanabhan Balaram
A right handed peptide helix containing a central double D-amino acid segment.
Chemical communications (Cambridge, England) 2002;(20):2454-5.
2002: Subrayashastry Aravinda; Narayanaswamy Shamala; Rai Rajkishore; Hosahudya N Gopi; Padmanabhan Balaram
A crystalline beta-hairpin peptide nucleated by a type I' Aib-D-Ala beta-turn: evidence for cross-strand aromatic interactions.
Angewandte Chemie (International ed. in English) 2002;41(20):3863-5.
2002: M Madan Babu; S Kumar Singh; Padmanabhan Balaram
A C-H triplebond O hydrogen bond stabilized polypeptide chain reversal motif at the C terminus of helices in proteins.
Journal of molecular biology 2002;322(4):871-80.
2002: Subrayashastry Aravinda; Narayanaswamy Shamala; Chittaranjan Das; Padmanabhan Balaram
Structural analysis of peptide helices containing centrally positioned lactic acid residues.
Biopolymers 2002;64(5):255-67.
2002: Vikram Shakkottai; R Sudha; Padmanabhan Balaram
Gramicidin S: a peptide model for protein glycation and reversal of glycation using nucleophilic amines.
The journal of peptide research : official journal of the American Peptide Society 2002;60(2):112-20.
2002: Kapil Maithal; Gudihal Ravindra; Hemalatha Balaram; Padmanabhan Balaram
Inhibition of plasmodium falciparum triose-phosphate isomerase by chemical modification of an interface cysteine. Electrospray ionization mass spectrometric analysis of differential cysteine reactivities.
The Journal of biological chemistry 2002;277(28):25106-14.
2002: Kapil Maithal; Gudihal Ravindra; G Nagaraj; S Kumar Singh; Hemalatha Balaram; Padmanabhan Balaram
Subunit interface mutation disrupting an aromatic cluster in Plasmodium falciparum triosephosphate isomerase: effect on dimer stability.
Protein engineering 2002;15(7):575-84.
2002: Janani Venkatraman; G A Nagana Gowda; Padmanabhan Balaram
Structural analysis of synthetic peptide fragments from EmrE, a multidrug resistance protein, in a membrane-mimetic environment.
Biochemistry 2002;41(21):6631-9.
2002: Janani Venkatraman; Gowda A Nagana Gowda; Padmanabhan Balaram
Design and construction of an open multistranded beta-sheet polypeptide stabilized by a disulfide bridge.
Journal of the American Chemical Society 2002;124(18):4987-94.
2002: Isabella L Karle; Hosahudya N Gopi; Padmanabhan Balaram
Infinite pleated beta -sheet formed by the beta-hairpin Boc-beta-Phe-beta-Phe-D-Pro-Gly-beta-Phe-beta-Phe-OMe.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(8):5160-4.
2002: Eugene Y Cheung; Emma E McCabe; Kenneth D M Harris; Roy L Johnston; Emilio Tedesco; K Muruga Poopathi Raja; Padmanabhan Balaram
C-HtriplebondO hydrogen bond mediated chain reversal in a peptide containing a gamma-amino acid residue, determined directly from powder X-ray diffraction data.
Angewandte Chemie (International ed. in English) 2002;41(3):494-6.
2001: M V Uma; R Sudha; Padmanabhan Balaram
Spermidine as a potential biosynthetic precursor to the 1,5-diazabicyclo[4:3:o]nonene residue in the efrapeptins.
The journal of peptide research : official journal of the American Peptide Society 2001;58(5):375-9.
2001: Isabella L Karle; Chittaranjan Das; Padmanabhan Balaram
Effects of hydrogen-bond deletion on peptide helices: structural characterization of depsipeptides containing lactic acid.
Biopolymers 2001;59(4):276-89.
2001: Janani Venkatraman; SC Shankaramma; Padmanabhan Balaram
Design of folded peptides.
Chemical reviews 2001;101(10):3131-52.
2001: S Kumar Singh; Kapil Maithal; Hemalatha Balaram; Padmanabhan Balaram
Synthetic peptides as inactivators of multimeric enzymes: inhibition of Plasmodium falciparum triosephosphate isomerase by interface peptides.
FEBS letters 2001;501(1):19-23.
2001: Janani Venkatraman; K Aggarwal; Padmanabhan Balaram
Helical peptide models for protein glycation: proximity effects in catalysis of the Amadori rearrangement.
Chemistry & biology 2001;8(7):611-25.
2001: SK Awasthi; SC Shankaramma; Srinivasarao Raghothama; Padmanabhan Balaram
Solvent-induced beta-hairpin to helix conformational transition in a designed peptide.
Biopolymers 2001;58(5):465-76.
2001: SS Ray; S Kumar Singh; Padmanabhan Balaram
An electrospray ionization mass spectrometry investigation of 1-anilino-8-naphthalene-sulfonate (ANS) binding to proteins.
Journal of the American Society for Mass Spectrometry 2001;12(4):428-38.
2001: Isabella L Karle; Hosahudya N Gopi; Padmanabhan Balaram
Peptide hybrids containing alpha - and beta-amino acids: structure of a decapeptide beta-hairpin with two facing beta-phenylalanine residues.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(7):3716-9.
2001: Chittaranjan Das; G A Naganagowda; Isabella L Karle; Padmanabhan Balaram
Designed beta-hairpin peptides with defined tight turn stereochemistry.
Biopolymers 2001;58(3):335-46.
2001: C Das; SC Shankaramma; Padmanabhan Balaram
Molecular carpentry: piecing together helices and hairpins in designed peptides.
Chemistry (Weinheim an der Bergstrasse, Germany) 2001;7(4):840-7.
2000: C Das; V Nayak; Srinivasarao Raghothama; Padmanabhan Balaram
Synthetic protein design: construction of a four-stranded beta-sheet structure and evaluation of its integrity in methanol-water systems.
The journal of peptide research : official journal of the American Peptide Society 2000;56(5):307-17.
2000: Girish Ratnaparkhi; S K Awasthi; P Geetha Rani; Padmanabhan Balaram; Raghavan Varadarajan
Structural and thermodynamic consequences of introducing alpha-aminoisobutyric acid in the S peptide of ribonuclease S.
Protein engineering 2000;13(10):697-702.
2000: R Kaul; Sankaran Banumathi; Devadasan Velmurugan; R Balaji Rao; Padmanabhan Balaram
Conformational choice at alpha,alpha-di-n-propylglycine residues: helical or fully extended structures?
Biopolymers 2000;54(3):159-67.
2000: Subrayashastry Aravinda; Narayanaswamy Shamala; A Pramanik; Chittaranjan Das; Padmanabhan Balaram
An unusual C-H...O hydrogen bond mediated reversal of polypeptide chain direction in a synthetic peptide helix.
Biochemical and biophysical research communications 2000;273(3):933-6.
2000: R Kaul; Sankaran Banumathi; Devadasan Velmurugan; K Ravikumar; R Balaji Rao; Padmanabhan Balaram
Context-dependent conformation of diethylglycine residues in peptides.
The journal of peptide research : official journal of the American Peptide Society 2000;55(4):271-8.
2000: Isabella L Karle; Chittaranjan Das; Padmanabhan Balaram
De novo protein design: crystallographic characterization of a synthetic peptide containing independent helical and hairpin domains.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(7):3034-7.
2000: S Vijayalakshmi; R Balaji Rao; I L Karle; Padmanabhan Balaram
Comparison of helix-stabilizing effects of alpha,alpha-dialkyl glycines with linear and cycloalkyl side chains.
Biopolymers 2000;53(1):84-98.
1999: Padmanabhan Balaram
De novo design: backbone conformational constraints in nucleating helices and beta-hairpins.
The journal of peptide research : official journal of the American Peptide Society 1999;54(3):195-9.
1999: SS Ray; Hemalatha Balaram; Padmanabhan Balaram
Unusual stability of a multiply nicked form of Plasmodium falciparum triosephosphate isomerase.
Chemistry & biology 1999;6(9):625-37.
1999: S Bhattacharjya; Janani Venkatraman; A Kumar; Padmanabhan Balaram
Fluoroalcohols as structure modifiers in peptides and proteins: hexafluoroacetone hydrate stabilizes a helical conformation of melittin at low pH.
The journal of peptide research : official journal of the American Peptide Society 1999;54(2):100-11.
1999: S S Velanker; RS Gokhale; SS Ray; B Gopal; S Parthasarathy; D V Santi; Padmanabhan Balaram; M R N Murthy
Disulfide engineering at the dimer interface of Lactobacillus casei thymidylate synthase: crystal structure of the T155C/E188C/C244T mutant.
Protein science : a publication of the Protein Society 1999;8(4):930-3.
1999: V Prasanna; B Gopal; M R N Murthy; D V Santi; Padmanabhan Balaram
Effect of amino acid substitutions at the subunit interface on the stability and aggregation properties of a dimeric protein: role of Arg 178 and Arg 218 at the Dimer interface of thymidylate synthase.
Proteins 1999;34(3):356-68.
1999: John H Konnert; Jean M Karle; Isabella L Karle; K Uma; Padmanabhan Balaram
Isomorphous replacement combined with anomalous dispersion in the linear equations: application to a crystal containing four nonapeptide conformers.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 2):448-57.
1999: B Gopal; SS Ray; RS Gokhale; Hemalatha Balaram; M R N Murthy; Padmanabhan Balaram
Cavity-creating mutation at the dimer interface of Plasmodium falciparum triosephosphate isomerase: restoration of stability by disulfide cross-linking of subunits.
Biochemistry 1999;38(1):478-86.
1999: RS Gokhale; SS Ray; Hemalatha Balaram; Padmanabhan Balaram
Unfolding of Plasmodium falciparum triosephosphate isomerase in urea and guanidinium chloride: evidence for a novel disulfide exchange reaction in a covalently cross-linked mutant.
Biochemistry 1999;38(1):423-31.
1999: R Kaul; Padmanabhan Balaram
Stereochemical control of peptide folding.
Bioorganic & medicinal chemistry 1999;7(1):105-17.
1998: K Gunasekaran; L Gomathi; C Ramakrishnan; J Chandrasekhar; Padmanabhan Balaram
Conformational interconversions in peptide beta-turns: analysis of turns in proteins and computational estimates of barriers.
Journal of molecular biology 1998;284(5):1505-16.
1998: V Prasanna; S Bhattacharjya; Padmanabhan Balaram
Synthetic interface peptides as inactivators of multimeric enzymes: inhibitory and conformational properties of three fragments from Lactobacillus casei thymidylate synthase.
Biochemistry 1998;37(19):6883-93.
1998: Isabella L Karle; M A Perozzo; V K Mishra; Padmanabhan Balaram
Crystal structure of the channel-forming polypeptide antiamoebin in a membrane-mimetic environment.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(10):5501-4.
1998: K Gunasekaran; Hampapathalu Nagarajaram; C Ramakrishnan; Padmanabhan Balaram
Stereochemical punctuation marks in protein structures: glycine and proline containing helix stop signals.
Journal of molecular biology 1998;275(5):917-32.
1998: S Bhattacharjya; SK Awasthi; PR Adiga; Padmanabhan Balaram
Folded conformations of antigenic peptides from riboflavin carrier protein in aqueous hexafluoroacetone.
Protein science : a publication of the Protein Society 1998;7(1):123-31.
1997: S Bhattacharjya; Padmanabhan Balaram
Effects of organic solvents on protein structures: observation of a structured helical core in hen egg-white lysozyme in aqueous dimethylsulfoxide.
Proteins 1997;29(4):492-507.
1997: K Gunasekaran; C Ramakrishnan; Padmanabhan Balaram
Beta-hairpins in proteins revisited: lessons for de novo design.
Protein engineering 1997;10(10):1131-41.
1997: I N Sujay Subbayya; SS Ray; Padmanabhan Balaram; Hemalatha Balaram
Metabolic enzymes as potential drug targets in Plasmodium falciparum.
The Indian journal of medical research 1997;106():79-94.
1997: R Rajan; SK Awasthi; S Bhattacharjya; Padmanabhan Balaram
"Teflon-coated peptides": hexafluoroacetone trihydrate as a structure stabilizer for peptides.
Biopolymers 1997;42(2):125-8.
1997: S S Velanker; SS Ray; RS Gokhale; S Suma; Hemalatha Balaram; Padmanabhan Balaram; M R N Murthy
Triosephosphate isomerase from Plasmodium falciparum: the crystal structure provides insights into antimalarial drug design.
Structure (London, England : 1993) 1997;5(6):751-61.
1997: S Datta; Narayanaswamy Shamala; A Banerjee; Padmanabhan Balaram
Hydrogen bonding in peptide helices. Analysis of two independent helices in the crystal structure of a peptide Boc-Val-Ala-Leu-Aib-Val-Ala-Phe-OMe.
The journal of peptide research : official journal of the American Peptide Society 1997;49(6):604-11.
1997: S Bhattacharjya; Padmanabhan Balaram
Hexafluoroacetone hydrate as a structure modifier in proteins: characterization of a molten globule state of hen egg-white lysozyme.
Protein science : a publication of the Protein Society 1997;6(5):1065-73.
1997: Isabella L Karle; A Banerjee; Padmanabhan Balaram
Design of two-helix motifs in peptides: crystal structure of a system of linked helices of opposite chirality and a model helix-linker peptide.
Folding & design 1997;2(4):203-10.
1996: A Banerjee; A Pramanik; S Bhattacharjya; Padmanabhan Balaram
Omega amino acids in peptide design: incorporation into helices.
Biopolymers 1996;39(6):769-77.
1996: K Gunasekaran; C Ramakrishnan; Padmanabhan Balaram
Disallowed Ramachandran conformations of amino acid residues in protein structures.
Journal of molecular biology 1996;264(1):191-8.
1996: R Rajan; Padmanabhan Balaram
A model for the interaction of trifluoroethanol with peptides and proteins.
International journal of peptide and protein research 1996;48(4):328-36.
1996: S Prasad; R B Rao; H Bergstrand; B Lundquist; E L Becker; Padmanabhan Balaram
Conformation-activity correlations for chemotactic tripeptide analogs incorporating dialkyl residues with linear and cyclic alkyl sidechains at position 2.
International journal of peptide and protein research 1996;48(4):312-8.
1996: S Datta; N Shamala; R Gurunath; Padmanabhan Balaram
Observation of a mixed antiparallel and parallel beta-sheet motif in the crystal structure of Boc-Ala-Ile-Aib-OMe.
International journal of peptide and protein research 1996;48(3):209-14.
1996: A Banerjee; Srinivasarao Raghothama; I L Karle; Padmanabhan Balaram
Ambidextrous molecules: cylindrical peptide structures formed by fusing left- and right-handed helices.
Biopolymers 1996;39(3):279-85.
1996: Isabella L Karle; S K Awasthi; Padmanabhan Balaram
A designed beta-hairpin peptide in crystals.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(16):8189-93.
1996: Isabella L Karle; R B Rao; R Kaul; S Prasad; Padmanabhan Balaram
Peptide design: crystal structure of a helical peptide module attached to a potentially nonhelical amino terminal segment.
Biopolymers 1996;39(1):75-83.
1996: RS Gokhale; S Agarwalla; D V Santi; Padmanabhan Balaram
Covalent reinforcement of a fragile region in the dimeric enzyme thymidylate synthase stabilizes the protein against chaotrope-induced unfolding.
Biochemistry 1996;35(22):7150-8.
1996: Isabella L Karle; R Gurunath; S Prasad; R B Rao; Padmanabhan Balaram
Crystal structures of a nonapeptide helix containing alpha, alpha-di-n-butylglycine (Dbg), Boc-Gly-Dbg-Ala-Val-Ala-Leu-Aib-Val-Leu-OMe.
International journal of peptide and protein research 1996;47(5):376-82.
1996: Isabella L Karle; A Banerjee; S Bhattacharjya; Padmanabhan Balaram
Solid state and solution conformations of a helical peptide with a central Gly-Gly segment.
Biopolymers 1996;38(4):515-26.
1996: S Agarwalla; RS Gokhale; D V Santi; Padmanabhan Balaram
Covalent tethering of the dimer interface annuls aggregation in thymidylate synthase.
Protein science : a publication of the Protein Society 1996;5(2):270-7.
1995: S K Awasthi; Srinivasarao Raghothama; Padmanabhan Balaram
A designed beta-hairpin peptide.
Biochemical and biophysical research communications 1995;216(1):375-81.
1995: K Gunasekaran; C Ramakrishnan; Padmanabhan Balaram
Stereochemical analysis of the antigenic tip of the V3 loop peptide of HIV-1 gp120.
International journal of peptide and protein research 1995;46(5):359-65.
1995: R Gurunath; T K Beena; PR Adiga; Padmanabhan Balaram
Enhancing peptide antigenicity by helix stabilization.
FEBS letters 1995;361(2-3):176-8.
1995: R Gurunath; Padmanabhan Balaram
A nonhelical, multiple beta-turn conformation in a glycine-rich heptapeptide fragment of trichogin A IV containing a single central alpha-aminoisobutyric acid residue.
Biopolymers 1995;35(1):21-9.
1995: Marco Crisma; G Valle; Claudio Toniolo; S Prasad; R B Rao; Padmanabhan Balaram
beta-turn conformations in crystal structures of model peptides containing alpha,alpha-di-n-propylglycine and alpha,alpha-di-n-butylglycine.
Biopolymers 1995;35(1):1-9.
1994: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Hydration and distortion of peptide helices in crystals. Alpha-helical structure of a dodecapeptide, Boc-(Ala-Leu-Aib)4-OMe.
International journal of peptide and protein research 1994;44(5):491-8.
1994: Isabella L Karle; J L Flippen-Anderson; R Gurunath; Padmanabhan Balaram
Facile transition between 3(10)- and alpha-helix: structures of 8-, 9-, and 10-residue peptides containing the -(Leu-Aib-Ala)2-Phe-Aib- fragment.
Protein science : a publication of the Protein Society 1994;3(9):1547-55.
1994: N Srinivasan; V S Anuradha; C Ramakrishnan; R Sowdhamini; Padmanabhan Balaram
Conformational characteristics of asparaginyl residues in proteins.
International journal of peptide and protein research 1994;44(2):112-22.
1994: R Gurunath; Padmanabhan Balaram
Incorporation of a potentially helix breaking D-Phe-Pro sequence into the center of a right handed 16 residue peptide helix.
Biochemical and biophysical research communications 1994;202(1):241-5.
1994: Isabella L Karle; Judith L Flippen-Anderson; S Agarwalla; Padmanabhan Balaram
Conformation of the flexible bent helix of Leu1-zervamicin in crystal C and a possible gating action for ion passage.
Biopolymers 1994;34(6):721-35.
1994: S Prasad; S Mitra; E Subramanian; devadasan velmurugan; R B Rao; Padmanabhan Balaram
Coexistence of folded and extended conformations of a tripeptide containing alpha, alpha -di-n-propylglycine in crystals.
Biochemical and biophysical research communications 1994;198(2):424-30.
1994: RS Gokhale; S Agarwalla; V S Francis; D V Santi; Padmanabhan Balaram
Thermal stabilization of thymidylate synthase by engineering two disulfide bridges across the dimer interface.
Journal of molecular biology 1994;235(1):89-94.
1994: K Aparna; Padmanabhan Balaram; S S Krishnamurthy; M Nethaji
Peptide-lanthanide interactions. Crystal structure of a europium(III)-triglycine complex.
International journal of peptide and protein research 1994;43(1):19-22.
1993: R Sowdhamini; C Ramakrishnan; Padmanabhan Balaram
Modelling multiple disulphide loop containing polypeptides by random conformation generation. The test cases of alpha-conotoxin GI and endothelin I.
Protein engineering 1993;6(8):873-82.
1993: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Peptide mimics for structural features in proteins. Crystal structures of three heptapeptide helices with a C-terminal 6-->1 hydrogen bond.
International journal of peptide and protein research 1993;42(5):401-10.
1993: K Uma; R Kishore; Padmanabhan Balaram
Stereochemical constraints in peptide design: analysis of the influence of a disulfide bridge and an alpha-aminoisobutyryl residue on the conformation of a hexapeptide.
Biopolymers 1993;33(6):865-71.
1993: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Unfolding of an alpha-helix in peptide crystals by solvation: conformational fragility in a heptapeptide.
Biopolymers 1993;33(5):827-37.
1993: Hampapathalu Nagarajaram; R Sowdhamini; C Ramakrishnan; Padmanabhan Balaram
Termination of right handed helices in proteins by residues in left handed helical conformations.
FEBS letters 1993;321(1):79-83.
1993: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Accommodation of a D-Phe residue into a right-handed 3(10)-helix: structure of Boc-D-Phe-(Aib)4-Gly-L-Leu-(Aib)2-OMe, an analogue of the amino terminal segment of antiamoebins and emerimicins.
Biopolymers 1993;33(3):401-7.
1992: Isabella L Karle; Judith L Flippen-Anderson; M Sukumar; Padmanabhan Balaram
Differences in hydration and association of helical Boc-Val-Ala-Leu-Aib-Val-Ala-Leu-(Val-Ala-Leu-Aib)2-OMe.xH2O in two crystalline polymorphs.
Journal of medicinal chemistry 1992;35(21):3885-9.
1992: S Agarwalla; I R Mellor; M S Sansom; I L Karle; J L Flippen-Anderson; K Uma; K Krishna; M Sukumar; Padmanabhan Balaram
Zervamicins, a structurally characterised peptide model for membrane ion channels.
Biochemical and biophysical research communications 1992;186(1):8-15.
1992: Isabella L Karle; Judith L Flippen-Anderson; M Sukumar; Padmanabhan Balaram
Helix packing of leucine-rich peptides: a parallel leucine ladder in the structure of Boc-Aib-Leu-Aib-Aib-Leu-Leu-Leu-Aib-Leu-Aib-OMe.
Proteins 1992;12(4):324-30.
1992: R Sowdhamini; N Srinivasan; C Ramakrishnan; Padmanabhan Balaram
Orthogonal beta beta motifs in proteins.
Journal of molecular biology 1992;223(4):845-51.
1992: Padmanabhan Balaram; K Krishna; M Sukumar; I R Mellor; M S Sansom
The properties of ion channels formed by zervamicins.
European biophysics journal : EBJ 1992;21(2):117-28.
1991: G Valle; Marco Crisma; Claudio Toniolo; R B Rao; M Sukumar; Padmanabhan Balaram
Stereochemistry of peptides containing 1-aminocycloheptane-1-carboxylic acid (Ac7c).
International journal of peptide and protein research 1991;38(6):511-8.
1991: Isabella L Karle; Judith L Flippen-Anderson; S Agarwalla; Padmanabhan Balaram
Crystal structure of [Leu1]zervamicin, a membrane ion-channel peptide: implications for gating mechanisms.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(12):5307-11.
1990: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Helix aggregation in peptide crystals: occurrence of either all parallel or antiparallel packing motifs for alpha-helices in polymorphs of Boc-Aib-Ala-Leu-Ala-Leu-Aib-Leu-Ala-Leu-Aib-OMe.
Biopolymers 1990;29(14):1835-45.
1990: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Parallel zippers formed by alpha-helical peptide columns in crystals of Boc-Aib-Glu(OBzl)-Leu-Aib-Ala-Leu-Aib-Ala-Lys(Z)-Aib-OMe.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(20):7921-5.
1990: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Hemalatha Balaram; Padmanabhan Balaram
Peptide design: influence of a guest Aib-Pro segment on the stereochemistry of an oligo-val sequence--solution conformations and crystal structure of Boc-(Val)2-Aib-Pro-(Val)3-OMe.
Biopolymers 1990;29(10-11):1433-42.
1990: N Srinivasan; R Sowdhamini; C Ramakrishnan; Padmanabhan Balaram
Conformations of disulfide bridges in proteins.
International journal of peptide and protein research 1990;36(2):147-55.
1990: Isabella L Karle; Padmanabhan Balaram
Structural characteristics of alpha-helical peptide molecules containing Aib residues.
Biochemistry 1990;29(29):6747-56.
1990: Isabella L Karle; Judith L Flippen-Anderson; M Sukumar; Padmanabhan Balaram
Parallel and antiparallel aggregation of alpha-helices. Crystal structures of two apolar decapeptides X-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe (X = Boc, Ac).
International journal of peptide and protein research 1990;35(6):518-26.
1990: Hemalatha Balaram; K Uma; Padmanabhan Balaram
Synthetic peptide models for protein secondary structures. Beta-sheet formation in acyclic cystine peptides.
International journal of peptide and protein research 1990;35(6):495-500.
1990: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Apolar peptide models for conformational heterogeneity, hydration, and packing of polypeptide helices: crystal structure of hepta- and octapeptides containing alpha-aminoisobutyric acid.
Proteins 1990;7(1):62-73.
1990: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Synthetic peptide helices in crystals: structure and antiparallel and skewed packing motifs for alpha-helices in two isomeric decapeptides.
Biopolymers 1990;30(7-8):719-31.
1989: R Sowdhamini; N Srinivasan; Brian Shoichet; D V Santi; C Ramakrishnan; Padmanabhan Balaram
Stereochemical modeling of disulfide bridges. Criteria for introduction into proteins by site-directed mutagenesis.
Protein engineering 1989;3(2):95-103.
1989: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Modular design of synthetic protein mimics. Characterization of the helical conformation of a 13-residue peptide in crystals.
Biochemistry 1989;28(16):6696-701.
1989: Isabella L Karle; Judith L Flippen-Anderson; R Kishore; Padmanabhan Balaram
Cystine peptides. Antiparallel beta-sheet conformation of the cyclic biscystine peptide [Boc-Cys-Ala-Cys-NHCH3]2.
International journal of peptide and protein research 1989;34(1):37-41.
1989: Claudio Toniolo; Marco Crisma; G Valle; G M Bonora; S Polinelli; E L Becker; R J Freer; R B Rao; Padmanabhan Balaram
Conformationally restricted formyl methionyl tripeptide chemoattractants: a three-dimensional structure-activity study of analogs incorporating a C alpha,alpha-dialkylated glycine at position 2.
Peptide research 1989;2(4):275-81.
1989: K Uma; Padmanabhan Balaram; P Kaur; A K Sharma; V S Chauhan
Conformations of peptides containing Z-alpha,beta-dehydroleucine (delta ZLeu). A comparison of Boc-Pro-delta ZLeu-Gly-NHEt and Boc-Pro-delta ZPhe-Gly-NHEt.
International journal of biological macromolecules 1989;11(3):169-71.
1989: V S Chauhan; K Uma; P Kaur; Padmanabhan Balaram
Conformations of dehydrophenylalanine containing peptides: nmr studies of an acyclic hexapeptide with two delta Z-Phe residues.
Biopolymers 1989;28(3):763-71.
1989: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Hemalatha Balaram; Padmanabhan Balaram
Alpha-helix and mixed 3(10)/alpha-helix in cocrystallized conformers of Boc-Aib-Val-Aib-Aib-Val-Val-Val-Aib-Val-Aib-OMe.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(3):765-9.
1988: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Aggregation studies in crystals of apolar helical peptides: Boc-Aib-Val-Ala-Leu-Aib-Val-Ala-Leu-Aib-OMe.
International journal of peptide and protein research 1988;32(6):536-43.
1988: Isabella L Karle; Judith L Flippen-Anderson; M Sukumar; Padmanabhan Balaram
Monoclinic polymorph of Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe(anhydrous). Parallel packing of 3(10)-/alpha-helices and a transition of helix type.
International journal of peptide and protein research 1988;31(6):567-76.
1988: R Kishore; Srinivasarao Raghothama; Padmanabhan Balaram
Synthetic peptide models for the redox-active disulfide loop of glutaredoxin. Conformational studies.
Biochemistry 1988;27(7):2462-71.
1988: K Uma; V S Chauhan; A Kumar; Padmanabhan Balaram
Conformations of dehydrophenylalanine containing peptides. Nuclear Overhauser effect study of two acyclic tetrapeptides.
International journal of peptide and protein research 1988;31(4):349-58.
1988: K Uma; Hemalatha Balaram; Srinivasarao Raghothama; Padmanabhan Balaram
Simultaneous observation of positive and negative nuclear Overhauser effects in oligopeptides due to segmental motion.
Biochemical and biophysical research communications 1988;151(1):153-7.
1988: Isabella L Karle; Judith L Flippen-Anderson; K Uma; Padmanabhan Balaram
Aqueous channels within apolar peptide aggregates: solvated helix of the alpha-aminoisobutyric acid (Aib)-containing peptide Boc-(Aib-Ala-Leu)3-Aib-OMe.2H2O.CH3OH in crystals.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(2):299-303.
1987: C Ramakrishnan; M Sukumar; Padmanabhan Balaram
Nuclear Overhauser effects as probes of peptide structure. A diagnostic for left-handed helical conformations.
Biochemical and biophysical research communications 1987;149(3):953-9.
1987: K L Puranam; Srinivasarao Raghothama; Padmanabhan Balaram
A 1H-NMR study of bilirubin IX alpha solubilization by cholate micelles: application of nuclear Overhauser effects.
Biochimica et biophysica acta 1987;922(1):67-77.
1987: Isabella L Karle; Judith L Flippen-Anderson; M Sukumar; Padmanabhan Balaram
Conformation of a 16-residue zervamicin IIA analog peptide containing three different structural features: 3(10)-helix, alpha-helix, and beta-bend ribbon.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(15):5087-91.
1987: R Kishore; Srinivasarao Raghothama; Padmanabhan Balaram
Cystine peptides: the intramolecular antiparallel beta-sheet conformation of a 20-membered cyclic peptide disulfide.
Biopolymers 1987;26(6):873-91.
1986: Isabella L Karle; M Sukumar; Padmanabhan Balaram
Parallel packing of alpha-helices in crystals of the zervamicin IIA analog Boc-Trp-Ile-Ala-Aib-Ile-Val-Aib-Leu-Aib-Pro-OMe.2H2O.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(24):9284-8.