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Frank Kolligs

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Colonography, Computed Tomographic

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Frank T Kolligs; Ulrich Mansmann; Axel Munte; Alexander Crispin; Anno Graser; Burkhard Göke
Risk factors for advanced neoplasia within subcentimetric polyps: implications for diagnostic imaging.
Anno Graser; Karin Herrmann; Burkhard Göke; Evelyn Lindner; Ulrich Mansmann; Anja Melzer; Dorothea Nagel; Maximilian F Reiser; Jörg Schirra; Petra Stieber; Frank T Kolligs
Magnetic resonance colonography for the detection of colorectal neoplasia in asymptomatic adults.
Armando Santoro; Roland M Schmid; Brian Schwartz; Morris Sherman; Jörg Trojan; Jean Luc Van Laethem; Hans Van Vlierberghe; Reinhard Von Roemeling; Alan Weiss; Lorenza Rimassa; Stefania Salvagni; Giovanni Abbadessa; Corrado Boni; Ivan Borbath; Peter Buggisch; Yinpu Chen; Luca Cicalese; Bruno Daniele; Antonio Gasbarrini; Guido Gerken; Cesare Gridelli; Ziad Hassoun; Frank T Kolligs; Maria E Lamar; Monica Lencioni; Steven Miles; Nicola Personeni; Camillo Porta
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study.

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All Publications

2013: Frank T Kolligs; Ulrich Mansmann; Axel Munte; Alexander Crispin; Anno Graser; Burkhard Göke
Risk factors for advanced neoplasia within subcentimetric polyps: implications for diagnostic imaging.
Gut 2013;62(6):863-70.
2013: Anno Graser; Karin Herrmann; Burkhard Göke; Evelyn Lindner; Ulrich Mansmann; Anja Melzer; Dorothea Nagel; Maximilian F Reiser; Jörg Schirra; Petra Stieber; Frank T Kolligs
Magnetic resonance colonography for the detection of colorectal neoplasia in asymptomatic adults.
Gastroenterology 2013;144(4):743-750.e2.
2013: Armando Santoro; Roland M Schmid; Brian Schwartz; Morris Sherman; Jörg Trojan; Jean Luc Van Laethem; Hans Van Vlierberghe; Reinhard Von Roemeling; Alan Weiss; Lorenza Rimassa; Stefania Salvagni; Giovanni Abbadessa; Corrado Boni; Ivan Borbath; Peter Buggisch; Yinpu Chen; Luca Cicalese; Bruno Daniele; Antonio Gasbarrini; Guido Gerken; Cesare Gridelli; Ziad Hassoun; Frank T Kolligs; Maria E Lamar; Monica Lencioni; Steven Miles; Nicola Personeni; Camillo Porta
Tivantinib for second-line treatment of advanced hepatocellular carcinoma: a randomised, placebo-controlled phase 2 study.
The lancet oncology 2013;14(1):55-63.
2012: Alexander B Philipp; Fritz Spelsberg; Petra Stieber; Andreas Herbst; Andreas Jung; Rolf Lamerz; Dorothea Nagel; Jens Neumann; Frank T Kolligs
Prognostic role of methylated free circulating DNA in colorectal cancer.
International journal of cancer. Journal international du cancer 2012;131(10):2308-19.
2012: Frank T Kolligs
[Screening for colorectal cancer. Current evidence and novel developments].
Der Radiologe 2012;52(6):504-10.
2012: Stefan Holdenrieder; Frank T Kolligs; Davit Manukyan; Jan Braess; Petra Stieber
Nature and dynamics of nucleosome release from neoplastic and non-neoplastic cells.
Anticancer research 2012;32(5):2179-83.
2012: Andreas Herbst; Frank T Kolligs
Detection of DNA hypermethylation in remote media of patients with colorectal cancer: new biomarkers for colorectal carcinoma.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2012;33(2):297-305.
2012: Frank T Kolligs
An alternative way for epithelial-to-mesenchymal transition in colorectal cancer via EIF5A2?
Gut 2012;61(4):473-4.
2012: Ralf-Thorsten Hoffmann; Tobias F Jakobs; Fabian Bamberg; Eva-Maria Dürr; Alexander Haug; Thomas K Helmberger; Philipp M Paprottka; Barbara Rauch; Maximilian F Reiser; Agnes Schön; Christoph T Trumm; Frank T Kolligs
Transarterial hepatic yttrium-90 radioembolization in patients with unresectable intrahepatic cholangiocarcinoma: factors associated with prolonged survival.
Cardiovascular and interventional radiology 2012;35(1):105-16.
2012: N Ashoori; F Bamberg; M D'Anastasi; Ralf-Thorsten Hoffmann; Frank T Kolligs; P Paprottka; A Peporte; Maximilian F Reiser; M Rentsch; Sabine I Siegert; J A Al-Tubaikh; Tobias F Jakobs
Multimodality treatment for early-stage hepatocellular carcinoma: a bridging therapy for liver transplantation.
Digestion 2012;86(4):338-48.
2012: Mark op den Winkel; Philip op den Winkel; Markus Rentsch; Julia Sappl; Petra Stieber; Gundula Straub; Christoph J Zech; Burkhard Göke; Rolf Lamerz; Dorothea Nagel; Thomas Nickel; Frank T Kolligs
Prognosis of patients with hepatocellular carcinoma. Validation and ranking of established staging-systems in a large western HCC-cohort.
PloS one 2012;7(10):e45066.
2012: N Ashoori; F Bamberg; Frank T Kolligs; P Paprottka; M F Reiser; M Rentsch; Christoph Trumm; Tobias F Jakobs
Multimodality treatment with conventional transcatheter arterial chemoembolization and radiofrequency ablation for unresectable hepatocellular carcinoma.
Digestion 2012;85(1):18-26.
2011: Andreas Herbst; Konstanze Rahmig; Petra Stieber; Alexander Philipp; Andreas Jung; Andrea Ofner; Alexander Crispin; Jens Neumann; Rolf Lamerz; Frank T Kolligs
Methylation of NEUROG1 in serum is a sensitive marker for the detection of early colorectal cancer.
The American journal of gastroenterology 2011;106(6):1110-8.
2011: L Schmidt; R Zachoval; H Diepolder; Frank T Kolligs
[Hepatitis A - combined prolonged biphasic and cholestatic course of disease].
Deutsche medizinische Wochenschrift (1946) 2011;136(20):1057-9.
2011: Thomas Mang; Frank T Kolligs; Claus Schaefer; Maxmilian F Reiser; Anno Graser
Comparison of diagnostic accuracy and interpretation times for a standard and an advanced 3D visualisation technique in CT colonography.
European radiology 2011;21(3):653-62.
2011: Frank T Kolligs; Alexander Crispin; Axel Munte; Andreas Wagner; Ulrich Mansmann; Burkhard Göke
Risk of advanced colorectal neoplasia according to age and gender.
PloS one 2011;6(5):e20076.
2010: Lydia Kriegl; Andreas Jung; Jutta Engel; Rene Jackstadt; Alexander L Gerbes; Eike Gallmeier; Jana Anni Reiche; Heiko Hermeking; Antonia Rizzani; Christiane J Bruns; Frank T Kolligs; Thomas Kirchner; Burkhard Göke; Enrico N De Toni
Expression, cellular distribution, and prognostic relevance of TRAIL receptors in hepatocellular carcinoma.
Clinical cancer research : an official journal of the American Association for Cancer Research 2010;16(22):5529-38.
2010: Jutta Maria Nagel; Lydia Kriegl; David Horst; Jutta Engel; Shiva Gautam; Christos S Mantzoros; Thomas Kirchner; Burkhard Göke; Frank T Kolligs
γ-Catenin is an independent prognostic marker in early stage colorectal cancer.
International journal of colorectal disease 2010;25(11):1301-9.
2010: Anno Graser; Frank T Kolligs
Authors' response to Hassan et al.
Gut 2010;59(6):860.
2010: Marlon R Schneider; Maik Dahlhoff; David Horst; Benjamin Hirschi; Konrad Trülzsch; Josef Müller-Höcker; Roger Vogelmann; Michael Allgäuer; Markus Gerhard; Sylvia Steininger; Eckhard Wolf; Frank T Kolligs
A key role for E-cadherin in intestinal homeostasis and Paneth cell maturation.
PloS one 2010;5(12):e14325.
2009: Andreas Herbst; Simone Helferich; Andrea Behrens; Burkhard Göke; Frank T Kolligs
The transcription factor ITF-2A induces cell cycle arrest via p21(Cip1).
Biochemical and biophysical research communications 2009;387(4):736-40.
2009: Andreas Herbst; Bommer Guido; Lydia Kriegl; Andreas Jung; Andrea Behrens; Endy Csanadi; Markus Gerhard; Christian Bolz; Rainer Riesenberg; Wolfgang Zimmermann; Wolfgang Dietmaier; Isabella Wolf; Thomas Brabletz; Burkhard Göke; Frank T Kolligs
ITF-2 is disrupted via allelic loss of chromosome 18q21, and ITF-2B expression is lost at the adenoma-carcinoma transition.
Gastroenterology 2009;137(2):639-48, 648.e1-9.
2009: Andreas Herbst; Maike Wallner; Konstanze Rahmig; Petra Stieber; Alexander Crispin; Rolf Lamerz; Frank T Kolligs
Methylation of helicase-like transcription factor in serum of patients with colorectal cancer is an independent predictor of disease recurrence.
European journal of gastroenterology & hepatology 2009;21(5):565-9.
2009: S R Mucha; A Rizzani; Alexander L Gerbes; P Camaj; Wolfgang E Thasler; C J Bruns; Sören Eichhorst; Eike Gallmeier; Frank T Kolligs; Burkhard Göke; Enrico N De Toni
JNK inhibition sensitises hepatocellular carcinoma cells but not normal hepatocytes to the TNF-related apoptosis-inducing ligand.
Gut 2009;58(5):688-98.
2009: Sebastian Baehs; Andreas Herbst; Susanne E Thieme; Claudia Perschl; Andrea Behrens; Silvio Scheel; Andreas Jung; Thomas Brabletz; Burkhard Göke; Helmut Blum; Frank T Kolligs
Dickkopf-4 is frequently down-regulated and inhibits growth of colorectal cancer cells.
Cancer letters 2009;276(2):152-9.
2009: Anno Graser; Petra Stieber; D Nagel; C Schäfer; D Horst; Hans-Christoph Becker; Konstantin Nikolaou; A Lottes; S Geisbüsch; H Kramer; A C Wagner; H Diepolder; Jörg Schirra; H J Roth; D Seidel; Burkhard Göke; Maximilian F Reiser; Frank T Kolligs
Comparison of CT colonography, colonoscopy, sigmoidoscopy and faecal occult blood tests for the detection of advanced adenoma in an average risk population.
Gut 2009;58(2):241-8.
2008: Maik Dahlhoff; David Horst; Markus Gerhard; Frank T Kolligs; Eckhard Wolf; Marlon R Schneider
Betacellulin stimulates growth of the mouse intestinal epithelium and increases adenoma multiplicity in Apc+/Min mice.
FEBS letters 2008;582(19):2911-5.
2008: Enrico N De Toni; Susanne E Thieme; Andreas Herbst; Andrea Behrens; Petra Stieber; Andreas Jung; Helmut Blum; Burkhard Göke; Frank T Kolligs
OPG is regulated by beta-catenin and mediates resistance to TRAIL-induced apoptosis in colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(15):4713-8.
2008: Stefan Holdenrieder; Frank T Kolligs; Petra Stieber
New horizons for diagnostic applications of circulating nucleosomes in blood?
Clinical chemistry 2008;54(7):1104-6.
2008: Andreas Herbst; Frank T Kolligs
A conserved domain in the transcription factor ITF-2B attenuates its activity.
Biochemical and biophysical research communications 2008;370(2):327-31.
2007: Anno Graser; Frank T Kolligs; Thomas Mang; C Schaefer; S Geisbüsch; Maximilian F Reiser; Hans-Christoph Becker
Computer-aided detection in CT colonography: initial clinical experience using a prototype system.
European radiology 2007;17(10):2608-15.
2007: Andreas Herbst; Frank T Kolligs
Wnt signaling as a therapeutic target for cancer.
Methods in molecular biology (Clifton, N.J.) 2007;361():63-91.
2006: Maike Wallner; Andreas Herbst; Andrea Behrens; Alexander Crispin; Petra Stieber; Burkhard Göke; Rolf Lamerz; Frank T Kolligs
Methylation of serum DNA is an independent prognostic marker in colorectal cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(24):7347-52.
2006: Anne Barbara Tietz; Antje Malo; Joachim Diebold; Alexey Kotlyarov; Andreas Herbst; Frank T Kolligs; Barbara Brandt-Nedelev; Walter Halangk; Matthias Gaestel; Burkhard Göke; Claus Schäfer
Gene deletion of MK2 inhibits TNF-alpha and IL-6 and protects against cerulein-induced pancreatitis.
American journal of physiology. Gastrointestinal and liver physiology 2006;290(6):G1298-306.
2005: Bommer Guido; Claudia Jäger; Eva-Maria Dürr; Sebastian Baehs; Sören Eichhorst; Thomas Brabletz; Gang Hu; Thomas Fröhlich; Georg Arnold; Dagmar C Kress; Burkhard Göke; Guido Bommer; Frank T Kolligs
DRO1, a gene down-regulated by oncogenes, mediates growth inhibition in colon and pancreatic cancer cells.
The Journal of biological chemistry 2005;280(9):7962-75.
2005: Konstanze Lenhard; Bommer Guido; Silke Asutay; Rolf Schauer; Thomas Brabletz; Burkhard Göke; Rolf Lamerz; Frank T Kolligs
Analysis of promoter methylation in stool: a novel method for the detection of colorectal cancer.
Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association 2005;3(2):142-9.
2003: Frank T Kolligs; Alexander L Gerbes; E M Dürr; Rolf Schauer; M Kessler; Tomas Jelinek; Thomas Löscher; Manfred Bilzer
[52-year-old patient with subcutaneous space-occupying lesion in immunosuppression].
Der Internist 2003;44(6):740-5.
2003: David Van Mater; Frank T Kolligs; Andrzej Dlugosz; Eric R Fearon
Transient activation of beta -catenin signaling in cutaneous keratinocytes is sufficient to trigger the active growth phase of the hair cycle in mice.
Genes & development 2003;17(10):1219-24.
2002: Janet Y Leung; Frank T Kolligs; Rong Wu; Yali Zhai; Rork Kuick; Samir Hanash; Kathleen R Cho; Eric R Fearon
Activation of AXIN2 expression by beta-catenin-T cell factor. A feedback repressor pathway regulating Wnt signaling.
The Journal of biological chemistry 2002;277(24):21657-65.
2002: Yali Zhai; Rong Wu; Donald R Schwartz; Danielle Darrah; Heather Reed; Frank T Kolligs; Marvin T Nieman; Eric R Fearon; Kathleen R Cho
Role of beta-catenin/T-cell factor-regulated genes in ovarian endometrioid adenocarcinomas.
The American journal of pathology 2002;160(4):1229-38.
2002: Frank T Kolligs; Marvin T Nieman; Ira Winer; Gang Hu; David Van Mater; Ying Feng; Ian M Smith; Rong Wu; Yali Zhai; Kathleen R Cho; Eric R Fearon
ITF-2, a downstream target of the Wnt/TCF pathway, is activated in human cancers with beta-catenin defects and promotes neoplastic transformation.
Cancer cell 2002;1(2):145-55.
2002: Frank T Kolligs; Bommer Guido; Burkhard Göke
Wnt/beta-catenin/tcf signaling: a critical pathway in gastrointestinal tumorigenesis.
Digestion 2002;66(3):131-44.
2001: noriaki sunaga; Takashi Kohno; Frank T Kolligs; Eric R Fearon; R Saito; Jun Yokota
Constitutive activation of the Wnt signaling pathway by CTNNB1 (beta-catenin) mutations in a subset of human lung adenocarcinoma.
Genes, chromosomes & cancer 2001;30(3):316-21.
2000: Y Sun; Frank T Kolligs; M O Hottiger; R Mosavin; Eric R Fearon; Gary Nabel
Regulation of beta -catenin transformation by the p300 transcriptional coactivator.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(23):12613-8.
2000: Frank T Kolligs; B Kolligs; Karen M Hajra; Gang Hu; M Tani; Kathleen R Cho; Eric R Fearon
gamma-catenin is regulated by the APC tumor suppressor and its oncogenic activity is distinct from that of beta-catenin.
Genes & development 2000;14(11):1319-31.
1999: Frank T Kolligs; Gang Hu; Chi Dang; Eric R Fearon
Neoplastic transformation of RK3E by mutant beta-catenin requires deregulation of Tcf/Lef transcription but not activation of c-myc expression.
Molecular and cellular biology 1999;19(8):5696-706.
1999: Karel Caca; Frank T Kolligs; X Ji; M Hayes; J Qian; Alan Yahanda; D L Rimm; J Costa; Eric R Fearon
Beta- and gamma-catenin mutations, but not E-cadherin inactivation, underlie T-cell factor/lymphoid enhancer factor transcriptional deregulation in gastric and pancreatic cancer.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1999;10(6):369-76.
1993: Ying Li; Frank T Kolligs; Chung Owyang
Mechanism of action of calcitonin gene-related peptide in inhibiting pancreatic enzyme secretion in rats.
Gastroenterology 1993;105(1):194-201.