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Nobukazu Komatsu

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Nobukazu Komatsu; Satoru Kuhara; Satoko Matsueda; Kei Matsuoka; Fukuko Moriya; Masanori Noguchi; Shigeki Shichijo; Shigetaka Suekane; Kousuke Tashiro; Akira Yamada; Atsushi Doi; Tetsuya Ioji; Kyogo Itoh; Tetsuro Sasada
Gene expression profiles in peripheral blood as a biomarker in cancer patients receiving peptide vaccination.
Kazumi Yoshida; Masanori Noguchi; Takashi Mine; Nobukazu Komatsu; Shigeru Yutani; Takato Ueno; Hiroaki Yanagimoto; Kouichirou Kawano; Kyogo Itoh; Akira Yamada
Characteristics of severe adverse events after peptide vaccination for advanced cancer patients: Analysis of 500 cases.
Kanako Iseki; Hiromi Matsunaga; Nobukazu Komatsu; Shigetaka Suekane; Masanori Noguchi; Kyogo Itoh; Akira Yamada
Evaluation of a new oil adjuvant for use in peptide-based cancer vaccination.

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2012: Nobukazu Komatsu; Satoru Kuhara; Satoko Matsueda; Kei Matsuoka; Fukuko Moriya; Masanori Noguchi; Shigeki Shichijo; Shigetaka Suekane; Kousuke Tashiro; Akira Yamada; Atsushi Doi; Tetsuya Ioji; Kyogo Itoh; Tetsuro Sasada
Gene expression profiles in peripheral blood as a biomarker in cancer patients receiving peptide vaccination.
Cancer 2012;118(12):3208-21.
2011: Kazumi Yoshida; Masanori Noguchi; Takashi Mine; Nobukazu Komatsu; Shigeru Yutani; Takato Ueno; Hiroaki Yanagimoto; Kouichirou Kawano; Kyogo Itoh; Akira Yamada
Characteristics of severe adverse events after peptide vaccination for advanced cancer patients: Analysis of 500 cases.
Oncology reports 2011;25(1):57-62.
2010: Kanako Iseki; Hiromi Matsunaga; Nobukazu Komatsu; Shigetaka Suekane; Masanori Noguchi; Kyogo Itoh; Akira Yamada
Evaluation of a new oil adjuvant for use in peptide-based cancer vaccination.
Cancer science 2010;101(10):2110-4.
2010: Masanori Noguchi; Tatsuyuki Kakuma; Hirotsugu Uemura; Yasutomo Nasu; Hiromi Kumon; Yasuhiko Hirao; Fukuko Moriya; Shigetaka Suekane; Kei Matsuoka; Nobukazu Komatsu; Shigeki Shichijo; Akira Yamada; Kyogo Itoh
A randomized phase II trial of personalized peptide vaccine plus low dose estramustine phosphate (EMP) versus standard dose EMP in patients with castration resistant prostate cancer.
Cancer immunology, immunotherapy : CII 2010;59(7):1001-9.
2010: Tetsuro Sasada; Nobukazu Komatsu; Shigetaka Suekane; Akira Yamada; Masanori Noguchi; Kyogo Itoh
Overcoming the hurdles of randomised clinical trials of therapeutic cancer vaccines.
European journal of cancer (Oxford, England : 1990) 2010;46(9):1514-9.
2009: Yasunobu Terasaki; Shigeki Shichijo; Yamei Niu; Nobukazu Komatsu; Masanori Noguchi; Satoru Todo; Kyogo Itoh
An HLA-A3-binding prostate acid phosphatase-derived peptide can induce CTLs restricted to HLA-A2 and -A24 alleles.
Cancer immunology, immunotherapy : CII 2009;58(11):1877-85.
2009: Shigeru Yutani; Nobukazu Komatsu; Shigeki Shichijo; Kazumi Yoshida; Hiroko Takedatsu; Minoru Itou; Ryoko Kuromatu; Tatsuya Ide; Masatoshi Tanaka; Michio Sata; Akira Yamada; Kyogo Itoh
Phase I clinical study of a peptide vaccination for hepatitis C virus-infected patients with different human leukocyte antigen-class I-A alleles.
Cancer science 2009;100(10):1935-42.
2009: Yamei Niu; Nobukazu Komatsu; Yoshihiro Komohara; Satoko Matsueda; Shigeru Yutani; Yuki Ishihara; Minoru Itou; Akira Yamada; Kyogo Itoh; Shigeki Shichijo
A peptide derived from hepatitis C virus (HCV) core protein inducing cellular responses in patients with HCV with various HLA class IA alleles.
Journal of medical virology 2009;81(7):1232-40.
2009: Elnisr Rashed Mohamed; Masayasu Naito; Yasuhiro Terasaki; Yamei Niu; Shojiro Gohara; Nobukazu Komatsu; Shigeki Shichijo; Kyogo Itoh; Masanori Noguchi
Capability of SART3(109-118) peptide to induce cytotoxic T lymphocytes from prostate cancer patients with HLA class I-A11, -A31 and -A33 alleles.
International journal of oncology 2009;34(2):529-36.
2008: Masayasu Naito; Kyogo Itoh; Nobukazu Komatsu; Yuichi Yamashita; Takafumi Shirakusa; Akira Yamada; Fukuko Moriya; Hitoshi Ayatuka; Elnisr Rashed Mohamed; Kei Matsuoka; Masanori Noguchi
Dexamethasone did not suppress immune boosting by personalized peptide vaccination for advanced prostate cancer patients.
The Prostate 2008;68(16):1753-62.
2008: Shojiro Gohara; Shigeki Shichijo; Nobukazu Komatsu; Seiya Okuda; Shigeru Yutani; Kyogo Itoh
Detection of IgE antibody specific to a hepatitis C virus-derived peptide being recognized by cellular immunity in patients with HCV infection.
Viral immunology 2008;21(3):365-9.
2008: Nobukazu Komatsu; Mamoru Harada; Masami Nakagawa; Yasuaki Tanaka; Takeharu Ono; Shojiro Gohara; Kimihiko Ohkubo; Kyogo Itoh
A correlation between symptom severity and unbalanced reactive IgA production in Japanese cedar pollinosis patients.
Asian Pacific journal of allergy and immunology / launched by the Allergy and Immunology Society of Thailand 2008;26(2-3):97-104.
2007: Yukoh Itoh; Yoshihiro Komohara; Nobukazu Komatsu; Takafumi Minami; Koujiro Saito; Masanori Noguchi; Kyogo Itoh; Mamoru Harada
New peptides of the polycomb group protein enhancer of zeste homolog 2 with the potential to induce cancer-reactive cytotoxic T lymphocytes in human leukocyte antigen-A2+ prostate cancer patients.
Oncology reports 2007;18(5):1231-7.
2007: Shigeru Yutani; Akira Yamada; Kazumi Yoshida; Yukari Takao; Mayumi Tamura; Nobukazu Komatsu; Tatsuya Ide; Masatoshi Tanaka; Michio Sata; Kyogo Itoh
Phase I clinical study of a personalized peptide vaccination for patients infected with hepatitis C virus (HCV) 1b who failed to respond to interferon-based therapy.
Vaccine 2007;25(42):7429-35.
2007: Satoko Matsueda; Akira Yamada; Yukari Takao; Mayumi Tamura; Nobukazu Komatsu; Shigeru Yutani; Tatsuya Ide; Michio Sata; Kyogo Itoh
A new epitope peptide derived from hepatitis C virus 1b possessing the capacity to induce cytotoxic T-lymphocytes in HCV1b-infected patients with HLA-A11, -A31, and -A33.
Cancer immunology, immunotherapy : CII 2007;56(9):1359-66.
2007: Masahiro Tanaka; Nobukazu Komatsu; Naoyoshi Terakawa; Yasuaki Yanagimoto; Masao Oka; Tetsuro Sasada; Takashi Mine; Shojiro Gouhara; Shigeki Shichijo; Seiya Okuda; Kyogo Itoh
Increased levels of IgG antibodies against peptides of the prostate stem cell antigen in the plasma of pancreatic cancer patients.
Oncology reports 2007;18(1):161-6.
2006: Shigenori Homma; Mamoru Harada; Hirohisa Yano; Sachiko Ogasawara; Shigeki Shichijo; Satoko Matsueda; Nobukazu Komatsu; Hiroki Shomura; Yoshiaki Maeda; Yuji Sato; Satoru Todo; Kyogo Itoh
Identification of squamous cell carcinoma antigen-derived peptides having the capacity of inducing cancer-reactive CTLs in HLA-A24+ cancer patients.
International journal of oncology 2006;29(3):577-87.
2006: Yi Wang; Yukari Takao; Mamoru Harada; Nobukazu Komatsu; Takeharu Ono; Michio Sata; Kyogo Itoh; Akira Yamada
Identification of hepatitis C virus (HCV) 2a-derived epitope peptides having the capacity to induce cytotoxic T lymphocytes in human leukocyte antigen-A24+ and HCV2a-infected patients.
Cellular immunology 2006;241(1):38-46.
2006: Masahiro Tanaka; Nobukazu Komatsu; Yasuaki Yanagimoto; Masao Oka; Shigeki Shichijo; Seiya Okuda; Kyogo Itoh
Development of a new diagnostic tool for pancreatic cancer: simultaneous measurement of antibodies against peptides recognized by cytotoxic T lymphocytes.
The Kurume medical journal 2006;53(3-4):63-70.
2005: Mayumi Tamura; Akira Yamada; Yukari Takao; Satoko Matsueda; Nobukazu Komatsu; Shigeru Yutani; Tatsuya Ide; Michio Sata; Kyogo Itoh
Identification of hepatitis C virus 1b-derived peptides recognized by both cellular and humoral immune systems in HCV1b(+) HLA-A24(+) patients.
Hepatology research : the official journal of the Japan Society of Hepatology 2005;32(4):227-34.
2005: Shigeki Shichijo; Masaaki Ito; Koichi Azuma; Nobukazu Komatsu; Yoshiaki Maeda; Yuki Ishihara; Toru Nakamura; Mamoru Harada; Kyogo Itoh
A unique gene having homology with the kinesin family member 18A encodes a tumour-associated antigen recognised by cytotoxic T lymphocytes from HLA-A2+ colon cancer patients.
European journal of cancer (Oxford, England : 1990) 2005;41(9):1323-30.
2005: Shigeki Shichijo; Yuki Ishihara; Koichi Azuma; Nobukazu Komatsu; Noriko Higashimoto; Masaaki Ito; Toru Nakamura; Takato Ueno; Mamoru Harada; Kyogo Itoh
ABCE1, a member of ATP-binding cassette transporter gene, encodes peptides capable of inducing HLA-A2-restricted and tumor-reactive cytotoxic T lymphocytes in colon cancer patients.
Oncology reports 2005;13(5):907-13.
2004: Shigeki Shichijo; Koichi Azuma; Nobukazu Komatsu; Masaaki Ito; Yoshiaki Maeda; Yuki Ishihara; Kyogo Itoh
Two proliferation-related proteins, TYMS and PGK1, could be new cytotoxic T lymphocyte-directed tumor-associated antigens of HLA-A2+ colon cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5828-36.
2004: Hiroki Shomura; Shigeki Shichijo; Nobukazu Komatsu; Satoko Matsueda; Takashi Mine; Toru Rikimaru; Yuji Sato; Satoru Todo; Kyogo Itoh
Identification of epidermal growth factor receptor-derived peptides recognised by both cellular and humoral immune responses in HLA-A24+ non-small cell lung cancer patients.
European journal of cancer (Oxford, England : 1990) 2004;40(11):1776-86.
2004: Takako Saisho Hattori; Nobukazu Komatsu; Shigeki Shichijo; Kyogo Itoh
Protein-bound polysaccharide K induced apoptosis of the human Burkitt lymphoma cell line, Namalwa.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 2004;58(4):226-30.
2004: Makoto Koga; Nobukazu Komatsu; Naoki Kawamoto; Shigeki Shichijo; Kyogo Itoh; Akira Yamada
Analysis of cellular localization of SART3 tumor antigen by a newly established monoclonal antibody: heterotopic expression of SART3 on the surface of B-lineage leukemic cells.
Oncology reports 2004;11(4):785-9.
2003: Shigeki Shichijo; Koichi Azuma; Nobukazu Komatsu; Naoki Kawamoto; Hiroko Takedatsu; Hiroki Shomura; Hiromi Sawamizu; Yoshiaki Maeda; Masaaki Ito; Kyogo Itoh
Identification of two novel tumor-associated antigens recognized by HLA-B46-restricted cytotoxic T lymphocytes.
International journal of molecular medicine 2003;12(6):895-902.
2003: Koichi Azuma; Shigeki Shichijo; Hiroko Takedatsu; Nobukazu Komatsu; Hiromi Sawamizu; Kyogo Itoh
Heat shock cognate protein 70 encodes antigenic epitopes recognised by HLA-B4601-restricted cytotoxic T lymphocytes from cancer patients.
British journal of cancer 2003;89(6):1079-85.
2002: Nobukazu Komatsu; Shigeki Shichijo; Yoshiaki Maeda; Kyogo Itoh
Measurement of interferon-gamma by high-throughput fluorometric microvolume assay technology system.
Journal of immunological methods 2002;263(1-2):169-76.