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Elizabeth Komives

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

Concepts & Ideas

Phenomena

Protein Binding

Chemicals & Drugs

Physiology

Protein Folding

Procedures

Occupations

Thermodynamics

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Publications

TOP 3
Deepa Balasubramaniam; Elizabeth A Komives
Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins.
Carla F Cervantes; H Jane Dyson; Lindsey D Handley; Shih-Che Sue; Elizabeth A Komives
Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα.
Paul M Gasper; Elizabeth A Komives; Phineus R L Markwick; Brian Fuglestad; J Andrew McCammon
Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities.

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All Publications

2013: Deepa Balasubramaniam; Elizabeth A Komives
Hydrogen-exchange mass spectrometry for the study of intrinsic disorder in proteins.
Biochimica et biophysica acta 2013;1834(6):1202-9.
2013: Carla F Cervantes; H Jane Dyson; Lindsey D Handley; Shih-Che Sue; Elizabeth A Komives
Long-range effects and functional consequences of stabilizing mutations in the ankyrin repeat domain of IκBα.
Journal of molecular biology 2013;425(5):902-13.
2012: Paul M Gasper; Elizabeth A Komives; Phineus R L Markwick; Brian Fuglestad; J Andrew McCammon
Allosteric networks in thrombin distinguish procoagulant vs. anticoagulant activities.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(52):21216-22.
2012: Lan Guo; Elizabeth A Komives; Majid Ghassemian; Paul Russell
Cadmium-induced proteome remodeling regulated by Spc1/Sty1 and Zip1 in fission yeast.
Toxicological sciences : an official journal of the Society of Toxicology 2012;129(1):200-12.
2012: Brian Fuglestad; Paul M Gasper; Phineus R L Markwick; J Andrew McCammon; Marco Tonelli; Elizabeth A Komives
The dynamic structure of thrombin in solution.
Biophysical journal 2012;103(1):79-88.
2012: H Jane Dyson; Elizabeth A Komives
Role of disorder in IκB-NFκB interaction.
IUBMB life 2012;64(6):499-505.
2012: Timothy O Jobe; Elizabeth A Komives; David G Mendoza-Cózatl; Allis Pham; Garo Akmakjian; Dong-Yul Sung; Julian I Schroeder
Feedback inhibition by thiols outranks glutathione depletion: a luciferase-based screen reveals glutathione-deficient γ-ECS and glutathione synthetase mutants impaired in cadmium-induced sulfate assimilation.
The Plant journal : for cell and molecular biology 2012;70(5):783-95.
2012: Nicholas P Schafer; Anat Burger; Patricio O Craig; Ryan M B Hoffman; Elizabeth A Komives; Peter G Wolynes
Discrete kinetic models from funneled energy landscape simulations.
PloS one 2012;7(12):e50635.
2012: Elizabeth A Komives
Consequences of fuzziness in the NFκB/IκBα interaction.
Advances in experimental medicine and biology 2012;725():74-85.
2011: Patricio O Craig; Diego U Ferreiro; Ryan M B Hoffman; Elizabeth A Komives; Joachim Lätzer; Patrick Weinkam; Peter G Wolynes
Prediction of native-state hydrogen exchange from perfectly funneled energy landscapes.
Journal of the American Chemical Society 2011;133(43):17463-72.
2011: Melinda M Mulvihill; Miklos Guttman; Elizabeth A Komives
Protein interactions among Fe65, the low-density lipoprotein receptor-related protein, and the amyloid precursor protein.
Biochemistry 2011;50(28):6208-16.
2011: Jorge A Lamboy; Kyung Suk Lee; Taekjip Ha; Hajin Kim; Elizabeth A Komives
Visualization of the nanospring dynamics of the IkappaBalpha ankyrin repeat domain in real time.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(25):10178-83.
2011: Nicholas A Treuheit; Muneera A Beach; Elizabeth A Komives
Thermodynamic compensation upon binding to exosite 1 and the active site of thrombin.
Biochemistry 2011;50(21):4590-6.
2011: Ingrid DeVries; Diego U Ferreiro; Ignacio Sánchez; Elizabeth A Komives
Folding kinetics of the cooperatively folded subdomain of the IκBα ankyrin repeat domain.
Journal of molecular biology 2011;408(1):163-76.
2011: Diego U Ferreiro; Joseph A Hegler; Elizabeth A Komives; Peter G Wolynes
On the role of frustration in the energy landscapes of allosteric proteins.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(9):3499-503.
2011: Shih-Che Sue; Vera Alverdi; Elizabeth A Komives; H Jane Dyson
Detection of a ternary complex of NF-kappaB and IkappaBalpha with DNA provides insights into how IkappaBalpha removes NF-kappaB from transcription sites.
Proceedings of the National Academy of Sciences of the United States of America 2011;108(4):1367-72.
2011: Carla F Cervantes; Simon Bergqvist; Magnus Kjaergaard; Gerard Kroon; Shih-Che Sue; H Jane Dyson; Elizabeth A Komives
The RelA nuclear localization signal folds upon binding to IκBα.
Journal of molecular biology 2011;405(3):754-64.
2010: Ingrid L Devries; Rachel J Hampton-Smith; Melinda M Mulvihill; Vera Alverdi; Daniel J Peet; Elizabeth A Komives
Consequences of IkappaB alpha hydroxylation by the factor inhibiting HIF (FIH).
FEBS letters 2010;584(23):4725-30.
2010: Erika Mathes; Lily Wang; Elizabeth A Komives; riya ghosh
Flexible regions within I{kappa}B{alpha} create the ubiquitin-independent degradation signal.
The Journal of biological chemistry 2010;285(43):32927-36.
2010: Ilya Gertsman; Chi-Yu Fu; Rick Huang; Elizabeth A Komives; John E Johnson
Critical salt bridges guide capsid assembly, stability, and maturation behavior in bacteriophage HK97.
Molecular & cellular proteomics : MCP 2010;9(8):1752-63.
2010: Miklos Guttman; J Helena Prieto; Tracy M Handel; Peter J Domaille; Elizabeth A Komives
Structure of the minimal interface between ApoE and LRP.
Journal of molecular biology 2010;398(2):306-19.
2010: Ilya Gertsman; Elizabeth A Komives; John E Johnson
HK97 maturation studied by crystallography and H/2H exchange reveals the structural basis for exothermic particle transitions.
Journal of molecular biology 2010;397(2):560-74.
2010: Diego U Ferreiro; Elizabeth A Komives
Molecular mechanisms of system control of NF-kappaB signaling by IkappaBalpha.
Biochemistry 2010;49(8):1560-7.
2010: Miklos Guttman; J Helena Prieto; Johnny E Croy; Elizabeth A Komives
Decoding of lipoprotein-receptor interactions: properties of ligand binding modules governing interactions with apolipoprotein E.
Biochemistry 2010;49(6):1207-16.
2010: Phineus R L Markwick; Carla F Cervantes; Barrett L Abel; Elizabeth A Komives; Martin Blackledge; J Andrew McCammon
Enhanced conformational space sampling improves the prediction of chemical shifts in proteins.
Journal of the American Chemical Society 2010;132(4):1220-1.
2009: Simon Bergqvist; Vera Alverdi; Benedicte Mengel; Alexander Hoffmann; riya ghosh; Elizabeth A Komives
Kinetic enhancement of NF-kappaBxDNA dissociation by IkappaBalpha.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(46):19328-33.
2009: Miklos Guttman; Gina N Betts; Helen Barnes; Majid Ghassemian; Peter van der Geer; Elizabeth A Komives
Interactions of the NPXY microdomains of the low density lipoprotein receptor-related protein 1.
Proteomics 2009;9(22):5016-28.
2009: Dong-Yul Sung; Tae-Houn Kim; Elizabeth A Komives; David G Mendoza-Cózatl; Julian I Schroeder
ARS5 is a component of the 26S proteasome complex, and negatively regulates thiol biosynthesis and arsenic tolerance in Arabidopsis.
The Plant journal : for cell and molecular biology 2009;59(5):802-13.
2009: Carla F Cervantes; Phineus R L Markwick; Shih-Che Sue; J Andrew McCammon; H Jane Dyson; Elizabeth A Komives
Functional dynamics of the folded ankyrin repeats of I kappa B alpha revealed by nuclear magnetic resonance.
Biochemistry 2009;48(33):8023-31.
2009: Ilya Gertsman; Lu Gan; Miklos Guttman; Kelly Lee; Jeffrey A Speir; Robert L Duda; Roger W Hendrix; Elizabeth A Komives; John E Johnson
An unexpected twist in viral capsid maturation.
Nature 2009;458(7238):646-50.
2008: Simon Bergqvist; riya ghosh; Elizabeth A Komives
The IkappaBalpha/NF-kappaB complex has two hot spots, one at either end of the interface.
Protein science : a publication of the Protein Society 2008;17(12):2051-8.
2008: Julia R Koeppe; Muneera A Beach; Abel Baerga-Ortiz; S Jordan Kerns; Elizabeth A Komives
Mutations in the fourth EGF-like domain affect thrombomodulin-induced changes in the active site of thrombin.
Biochemistry 2008;47(41):10933-9.
2008: Stephanie M E Truhlar; Carla F Cervantes; Justin W Torpey; Magnus Kjaergaard; Elizabeth A Komives
Rapid mass spectrometric analysis of 15N-Leu incorporation fidelity during preparation of specifically labeled NMR samples.
Protein science : a publication of the Protein Society 2008;17(9):1636-9.
2008: Shih-Che Sue; Carla Cervantes; Elizabeth A Komives; H Jane Dyson
Transfer of flexibility between ankyrin repeats in IkappaB* upon formation of the NF-kappaB complex.
Journal of molecular biology 2008;380(5):917-31.
2008: Stephanie M E Truhlar; Erika Mathes; Carla F Cervantes; riya ghosh; Elizabeth A Komives
Pre-folding IkappaBalpha alters control of NF-kappaB signaling.
Journal of molecular biology 2008;380(1):67-82.
2008: Gina N Betts; Peter van der Geer; Elizabeth A Komives
Structural and functional consequences of tyrosine phosphorylation in the LRP1 cytoplasmic domain.
The Journal of biological chemistry 2008;283(23):15656-64.
2008: Diego U Ferreiro; Aleksandra M Walczak; Elizabeth A Komives; Peter G Wolynes
The energy landscapes of repeat-containing proteins: topology, cooperativity, and the folding funnels of one-dimensional architectures.
PLoS computational biology 2008;4(5):e1000070.
2008: Stephanie M E Truhlar; Elizabeth A Komives
LRR domain folding: just put a cap on it!
Structure (London, England : 1993) 2008;16(5):655-7.
2008: Chun-Ming Huang; Justin W Torpey; Yu-Tseung Liu; Yun-Ru Chen; Katherine E Williams; Elizabeth A Komives; Richard L Gallo
A peptide with a ProGln C terminus in the human saliva peptidome exerts bactericidal activity against Propionibacterium acnes.
Antimicrobial agents and chemotherapy 2008;52(5):1834-6.
2008: David G Mendoza-Cózatl; Emerald Butko; Franziska Springer; Justin W Torpey; Elizabeth A Komives; Julia Kehr; Julian I Schroeder
Identification of high levels of phytochelatins, glutathione and cadmium in the phloem sap of Brassica napus. A role for thiol-peptides in the long-distance transport of cadmium and the effect of cadmium on iron translocation.
The Plant journal : for cell and molecular biology 2008;54(2):249-59.
2008: Doug Barrick; Diego U Ferreiro; Elizabeth A Komives
Folding landscapes of ankyrin repeat proteins: experiments meet theory.
Current opinion in structural biology 2008;18(1):27-34.
2007: Diego U Ferreiro; Joseph A Hegler; Elizabeth A Komives; Peter G Wolynes
Localizing frustration in native proteins and protein assemblies.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(50):19819-24.
2007: Ganesh S Anand; Matthew Hotchko; Simon H J Brown; Lynn F Ten Eyck; Elizabeth A Komives; Susan S Taylor
R-subunit isoform specificity in protein kinase A: distinct features of protein interfaces in PKA types I and II by amide H/2H exchange mass spectrometry.
Journal of molecular biology 2007;374(2):487-99.
2007: Xiaohua Wu; Zhi-fang Li; Randolph Brooks; Elizabeth A Komives; Justin W Torpey; Eva Engvall; Steven L Gonias; G Diane Shelton
Autoantibodies in canine masticatory muscle myositis recognize a novel myosin binding protein-C family member.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(7):4939-44.
2007: Diego U Ferreiro; Elizabeth A Komives
The plastic landscape of repeat proteins.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(19):7735-6.
2007: Joachim Lätzer; Garegin A Papoian; Michael C Prentiss; Elizabeth A Komives; Peter G Wolynes
Induced fit, folding, and recognition of the NF-kappaB-nuclear localization signals by IkappaBalpha and IkappaBbeta.
Journal of molecular biology 2007;367(1):262-74.
2007: Dong-Yul Sung; David Lee; Hugh Harris; Andrea Raab; Jörg Feldmann; Andrew A Meharg; Bryan Kumabe; Elizabeth A Komives; Julian I Schroeder
Identification of an arsenic tolerant double mutant with a thiol-mediated component and increased arsenic tolerance in phyA mutants.
The Plant journal : for cell and molecular biology 2007;49(6):1064-75.
2007: Diego U Ferreiro; Carla F Cervantes; Stephanie M E Truhlar; Samuel S Cho; Peter G Wolynes; Elizabeth A Komives
Stabilizing IkappaBalpha by "consensus" design.
Journal of molecular biology 2007;365(4):1201-16.
2006: Stephanie M E Truhlar; Justin W Torpey; Elizabeth A Komives
Regions of IkappaBalpha that are critical for its inhibition of NF-kappaB.DNA interaction fold upon binding to NF-kappaB.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(50):18951-6.
2006: Stephanie M E Truhlar; Carrie H. Croy; Justin W Torpey; Julia R Koeppe; Elizabeth A Komives
Solvent accessibility of protein surfaces by amide H/2H exchange MALDI-TOF mass spectrometry.
Journal of the American Society for Mass Spectrometry 2006;17(11):1490-7.
2006: Simon Bergqvist; Carrie H. Croy; Magnus Kjaergaard; Tom Huxford; riya ghosh; Elizabeth A Komives
Thermodynamics reveal that helix four in the NLS of NF-kappaB p65 anchors IkappaBalpha, forming a very stable complex.
Journal of molecular biology 2006;360(2):421-34.
2006: Julia R Koeppe; Elizabeth A Komives
Amide H/2H exchange reveals a mechanism of thrombin activation.
Biochemistry 2006;45(25):7724-32.
2006: Alice Chen; Elizabeth A Komives; Julian I Schroeder
An improved grafting technique for mature Arabidopsis plants demonstrates long-distance shoot-to-root transport of phytochelatins in Arabidopsis.
Plant physiology 2006;141(1):108-20.
2006: Jianxin Shi; Julia R Koeppe; Elizabeth A Komives; Palmer Taylor
Ligand-induced conformational changes in the acetylcholine-binding protein analyzed by hydrogen-deuterium exchange mass spectrometry.
The Journal of biological chemistry 2006;281(17):12170-7.
2006: Matthew Hotchko; Ganesh S Anand; Elizabeth A Komives; Lynn F Ten Eyck
Automated extraction of backbone deuteration levels from amide H/2H mass spectrometry experiments.
Protein science : a publication of the Protein Society 2006;15(3):583-601.
2005: Diego U Ferreiro; Samuel S Cho; Elizabeth A Komives; Peter G Wolynes
The energy landscape of modular repeat proteins: topology determines folding mechanism in the ankyrin family.
Journal of molecular biology 2005;354(3):679-92.
2005: Julia R Koeppe; Almagoul Seitova; Timothy Mather; Elizabeth A Komives
Thrombomodulin tightens the thrombin active site loops to promote protein C activation.
Biochemistry 2005;44(45):14784-91.
2005: Jeffrey G Mandell; Abel Baerga-Ortiz; Carrie H. Croy; Arnold M Falick; Elizabeth A Komives
Application of amide proton exchange mass spectrometry for the study of protein-protein interactions.
Current protocols in protein science / editorial board, John E. Coligan ... [et al.] 2005;Chapter 20():Unit20.9.
2005: Judith H Prieto; Benedetta A Sampoli Benitez; Giuseppe Melacini; David A Johnson; Matthew J Wood; Elizabeth A Komives
Dynamics of the fragment of thrombomodulin containing the fourth and fifth epidermal growth factor-like domains correlate with function.
Biochemistry 2005;44(4):1225-33.
2005: Matthew J Wood; Judith Helena Prieto; Elizabeth A Komives
Structural and functional consequences of methionine oxidation in thrombomodulin.
Biochimica et biophysica acta 2005;1703(2):141-7.
2005: Jeffrey G Mandell; Abel Baerga-Ortiz; Arnold M Falick; Elizabeth A Komives
Measurement of solvent accessibility at protein-protein interfaces.
Methods in molecular biology (Clifton, N.J.) 2005;305():65-80.
2004: Carrie H. Croy; Simon Bergqvist; Tom Huxford; riya ghosh; Elizabeth A Komives
Biophysical characterization of the free IkappaBalpha ankyrin repeat domain in solution.
Protein science : a publication of the Protein Society 2004;13(7):1767-77.
2004: Johnny E Croy; Theodore Brandon; Elizabeth A Komives
Two apolipoprotein E mimetic peptides, ApoE(130-149) and ApoE(141-155)2, bind to LRP1.
Biochemistry 2004;43(23):7328-35.
2004: Carrie H. Croy; Julia R Koeppe; Simon Bergqvist; Elizabeth A Komives
Allosteric changes in solvent accessibility observed in thrombin upon active site occupation.
Biochemistry 2004;43(18):5246-55.
2004: Abel Baerga-Ortiz; Simon Bergqvist; Jeffrey G Mandell; Elizabeth A Komives
Two different proteins that compete for binding to thrombin have opposite kinetic and thermodynamic profiles.
Protein science : a publication of the Protein Society 2004;13(1):166-76.
2003: Johnny E Croy; William D Shin; Mary Knauer; Daniel J Knauer; Elizabeth A Komives
All three LDL receptor homology regions of the LDL receptor-related protein bind multiple ligands.
Biochemistry 2003;42(44):13049-57.
2003: Ganesh S Anand; Dennis Law; Jeffrey G Mandell; Aaron N Snead; Igor Tsigelny; Susan S Taylor; Lynn F Ten Eyck; Elizabeth A Komives
Identification of the protein kinase A regulatory RIalpha-catalytic subunit interface by amide H/2H exchange and protein docking.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(23):13264-9.
2003: Matthew J Wood; L Amaya Becvar; Judith Helena Prieto; Giuseppe Melacini; Elizabeth A Komives
NMR structures reveal how oxidation inactivates thrombomodulin.
Biochemistry 2003;42(41):11932-42.
2003: Lori L Jennings; Michael Malecki; Elizabeth A Komives; Palmer Taylor
Direct analysis of the kinetic profiles of organophosphate-acetylcholinesterase adducts by MALDI-TOF mass spectrometry.
Biochemistry 2003;42(37):11083-91.
2002: Tom Huxford; Dennis Mishler; Christopher Phelps; De-Bin Huang; Lei Lei Sengchanthalangsy; Ryan Reeves; Carrie A Hughes; Elizabeth A Komives; riya ghosh
Solvent exposed non-contacting amino acids play a critical role in NF-kappaB/IkappaBalpha complex formation.
Journal of molecular biology 2002;324(4):587-97.
2002: Ganesh S Anand; Carrie A Hughes; John M Jones; Susan S Taylor; Elizabeth A Komives
Amide H/2H exchange reveals communication between the cAMP and catalytic subunit-binding sites in the R(I)alpha subunit of protein kinase A.
Journal of molecular biology 2002;323(2):377-86.
2002: Jennifer A Whiles; Kerney Jebrell Glover; Regitze R Vold; Elizabeth A Komives
Methods for studying transmembrane peptides in bicelles: consequences of hydrophobic mismatch and peptide sequence.
Journal of magnetic resonance (San Diego, Calif. : 1997) 2002;158(1-2):149-56.
2002: Abel Baerga-Ortiz; Carrie A Hughes; Jeffrey G Mandell; Elizabeth A Komives
Epitope mapping of a monoclonal antibody against human thrombin by H/D-exchange mass spectrometry reveals selection of a diverse sequence in a highly conserved protein.
Protein science : a publication of the Protein Society 2002;11(6):1300-8.
2001: Kerney Jebrell Glover; Jennifer A Whiles; Matthew J Wood; Giuseppe Melacini; Elizabeth A Komives; Regitze R Vold
Conformational dimorphism and transmembrane orientation of prion protein residues 110-136 in bicelles.
Biochemistry 2001;40(44):13137-42.
2001: Kerney Jebrell Glover; Jennifer A Whiles; G Wu; N Yu; Raymond A Deems; Jochem Struppe; R E Stark; Elizabeth A Komives; Regitze R Vold
Structural evaluation of phospholipid bicelles for solution-state studies of membrane-associated biomolecules.
Biophysical journal 2001;81(4):2163-71.
2001: Carrie A Hughes; Jeffrey G Mandell; Ganesh S Anand; Ann M Stock; Elizabeth A Komives
Phosphorylation causes subtle changes in solvent accessibility at the interdomain interface of methylesterase CheB.
Journal of molecular biology 2001;307(4):967-76.
2001: Jeffrey G Mandell; Abel Baerga-Ortiz; S Akashi; K Takio; Elizabeth A Komives
Solvent accessibility of the thrombin-thrombomodulin interface.
Journal of molecular biology 2001;306(3):575-89.
2001: Jennifer A Whiles; R Brasseur; Kerney Jebrell Glover; Giuseppe Melacini; Elizabeth A Komives; Regitze R Vold
Orientation and effects of mastoparan X on phospholipid bicelles.
Biophysical journal 2001;80(1):280-93.
2000: Benedetta A Sampoli Benitez; Elizabeth A Komives
Disulfide bond plasticity in epidermal growth factor.
Proteins 2000;40(1):168-74.
2000: Matthew J Wood; Benedetta A Sampoli Benitez; Elizabeth A Komives
Solution structure of the smallest cofactor-active fragment of thrombomodulin.
Nature structural biology 2000;7(3):200-4.
2000: Abel Baerga-Ortiz; A R Rezaie; Elizabeth A Komives
Electrostatic dependence of the thrombin-thrombomodulin interaction.
Journal of molecular biology 2000;296(2):651-8.
1999: Kerney Jebrell Glover; P M Martini; Regitze R Vold; Elizabeth A Komives
Preparation of insoluble transmembrane peptides: glycophorin-A, prion (110-137), and FGFR (368-397).
Analytical biochemistry 1999;272(2):270-4.
1999: Z Zhang; Elizabeth A Komives; Shigetoshi Sugio; S C Blacklow; N Narayana; Nguyen-Huu Xuong; A M Stock; Gregory A Petsko; Dagmar Ringe
The role of water in the catalytic efficiency of triosephosphate isomerase.
Biochemistry 1999;38(14):4389-97.
1999: S Mentz; Sonsoles de Lacalle; Abel Baerga-Ortiz; Mary Knauer; Daniel J Knauer; Elizabeth A Komives
Mechanism of thrombin clearance by human astrocytoma cells.
Journal of neurochemistry 1999;72(3):980-7.
1999: Matthew J Wood; Elizabeth A Komives
Production of large quantities of isotopically labeled protein in Pichia pastoris by fermentation.
Journal of biomolecular NMR 1999;13(2):149-59.
1998: Jeffrey G Mandell; Arnold M Falick; Elizabeth A Komives
Identification of protein-protein interfaces by decreased amide proton solvent accessibility.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(25):14705-10.
1998: Jochem Struppe; Elizabeth A Komives; Susan S Taylor; Regitze R Vold
2H NMR studies of a myristoylated peptide in neutral and acidic phospholipid bicelles.
Biochemistry 1998;37(44):15523-7.
1998: Jeffrey G Mandell; Arnold M Falick; Elizabeth A Komives
Measurement of amide hydrogen exchange by MALDI-TOF mass spectrometry.
Analytical chemistry 1998;70(19):3987-95.
1998: M A Gleeson; C E White; D P Meininger; Elizabeth A Komives
Generation of protease-deficient strains and their use in heterologous protein expression.
Methods in molecular biology (Clifton, N.J.) 1998;103():81-94.
1997: Benedetta A Sampoli Benitez; M J Hunter; D P Meininger; Elizabeth A Komives
Structure of the fifth EGF-like domain of thrombomodulin: An EGF-like domain with a novel disulfide-bonding pattern.
Journal of molecular biology 1997;273(4):913-26.
1997: Alessandro Vindigni; C E White; Elizabeth A Komives; Enrico Di Cera
Energetics of thrombin-thrombomodulin interaction.
Biochemistry 1997;36(22):6674-81.
1996: Elizabeth A Komives; J C Lougheed; Z Zhang; S Sugio; N Narayana; Nguyen-Huu Xuong; Gregory A Petsko; Dagmar Ringe
The structural basis for pseudoreversion of the H95N lesion by the secondary S96P mutation in triosephosphate isomerase.
Biochemistry 1996;35(48):15474-84.
1996: C E White; M J Hunter; D P Meininger; S Garrod; Elizabeth A Komives
The fifth epidermal growth factor-like domain of thrombomodulin does not have an epidermal growth factor-like disulfide bonding pattern.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(19):10177-82.
1995: C E White; M J Hunter; D P Meininger; L R White; Elizabeth A Komives
Large-scale expression, purification and characterization of small fragments of thrombomodulin: the roles of the sixth domain and of methionine 388.
Protein engineering 1995;8(11):1177-87.
1995: Elizabeth A Komives; J C Lougheed; K Liu; S Sugio; Z Zhang; Gregory A Petsko; Dagmar Ringe
The structural basis for pseudoreversion of the E165D lesion by the secondary S96P mutation in triosephosphate isomerase depends on the positions of active site water molecules.
Biochemistry 1995;34(41):13612-21.
1995: M J Hunter; Elizabeth A Komives
Thrombin-binding affinities of different disulfide-bonded isomers of the fifth EGF-like domain of thrombomodulin.
Protein science : a publication of the Protein Society 1995;4(10):2129-37.
1995: D P Meininger; M J Hunter; Elizabeth A Komives
Synthesis, activity, and preliminary structure of the fourth EGF-like domain of thrombomodulin.
Protein science : a publication of the Protein Society 1995;4(9):1683-95.
1995: M J Hunter; Elizabeth A Komives
Deprotection of S-acetamidomethyl cysteine-containing peptides by silver trifluoromethanesulfonate avoids the oxidation of methionines.
Analytical biochemistry 1995;228(1):173-7.
1995: J C Lougheed; C L Bowman; D P Meininger; Elizabeth A Komives
Thrombin inhibition by cyclic peptides from thrombomodulin.
Protein science : a publication of the Protein Society 1995;4(4):773-80.
1994: C E White; N M Kempi; Elizabeth A Komives
Expression of highly disulfide-bonded proteins in Pichia pastoris.
Structure (London, England : 1993) 1994;2(11):1003-5.
1994: Z Zhang; S Sugio; Elizabeth A Komives; K D Liu; J R Knowles; Gregory A Petsko; Dagmar Ringe
Crystal structure of recombinant chicken triosephosphate isomerase-phosphoglycolohydroxamate complex at 1.8-A resolution.
Biochemistry 1994;33(10):2830-7.
1994: D Joseph-McCarthy; E Lolis; Elizabeth A Komives; Gregory A Petsko
Crystal structure of the K12M/G15A triosephosphate isomerase double mutant and electrostatic analysis of the active site.
Biochemistry 1994;33(10):2815-23.
1994: P J Lodi; L C Chang; J R Knowles; Elizabeth A Komives
Triosephosphate isomerase requires a positively charged active site: the role of lysine-12.
Biochemistry 1994;33(10):2809-14.
1994: D Joseph-McCarthy; L E Rost; Elizabeth A Komives; Gregory A Petsko
Crystal structure of the mutant yeast triosephosphate isomerase in which the catalytic base glutamic acid 165 is changed to aspartic acid.
Biochemistry 1994;33(10):2824-9.
1992: B J Warn-Cramer; G J Broze; Elizabeth A Komives
cDNA sequence of rabbit tissue factor pathway inhibitor.
Nucleic acids research 1992;20(13):3548.
1991: Elizabeth A Komives; L C Chang; E Lolis; R F Tilton; Gregory A Petsko; J R Knowles
Electrophilic catalysis in triosephosphate isomerase: the role of histidine-95.
Biochemistry 1991;30(12):3011-9.