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Makoto Komiyama

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Chemicals & Drugs

Phenomena

Concepts & Ideas

Procedures

Spectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization

Genes & Molecular Sequences

Single Nucleotide Polymorphism

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Co-Publications
Name
26
Sumaoka, Jun
26
Yamamoto, Yoji
24
Kuzuya, Akinori
23
Asanuma, Hiroyuki
11
Liang, Xingguo
10
Xu, Yan
10
Zhou, Jing-Min
8
Aiba, Yuichiro
7
Kashida, Hiromu
7
Liu, Mingzhe
7
Aburatani, Hiroyuki
7
Mizoguchi, Ryo
7
Kitamura, Yoshihito
7
Uehara, Akihiko
6
Takarada, Tohru

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Publications

TOP 3
Katada Hitoshi; Chen Hsuan Jung; Shigi Narumi; Komiyama Makoto
Homologous recombination in human cells using artificial restriction DNA cutter.
Ito Kenichiro; Katada Hitoshi; Shigi Narumi; Komiyama Makoto
Site-selective scission of human genome by artificial restriction DNA cutter.
Ishizuka Takumi; Tedeschi Tullia; Corradini Roberto; Komiyama Makoto; Sforza Stefano; Marchelli Rosangela
SSB-assisted duplex invasion of preorganized PNA into double-stranded DNA.

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All Publications

2009: Katada Hitoshi; Chen Hsuan Jung; Shigi Narumi; Komiyama Makoto
Homologous recombination in human cells using artificial restriction DNA cutter.
Chemical communications (Cambridge, England) 2009;(43):6545-7.
2009: Ito Kenichiro; Katada Hitoshi; Shigi Narumi; Komiyama Makoto
Site-selective scission of human genome by artificial restriction DNA cutter.
Chemical communications (Cambridge, England) 2009;(43):6542-4.
2009: Ishizuka Takumi; Tedeschi Tullia; Corradini Roberto; Komiyama Makoto; Sforza Stefano; Marchelli Rosangela
SSB-assisted duplex invasion of preorganized PNA into double-stranded DNA.
Chembiochem : a European journal of chemical biology 2009;10(16):2607-12.
2009: Kuzuya Akinori; Komiyama Makoto
Design and construction of a box-shaped 3D-DNA origami.
Chemical communications (Cambridge, England) 2009;(28):4182-4.
2009: Akiba Hiroki; Sumaoka Jun; Komiyama Makoto
Selective detection of phosphotyrosine in the presence of various phosphate-containing biomolecules with the aid of a terbium(III) complex.
Chembiochem : a European journal of chemical biology 2009;10(11):1773-6.
2009: Kuzuya Akinori; Kimura Mayumi; Numajiri Kentaro; Koshi Naohiro; Ohnishi Toshiyuki; Okada Fuminori; Komiyama Makoto
Precisely programmed and robust 2D streptavidin nanoarrays by using periodical nanometer-scale wells embedded in DNA origami assembly.
Chembiochem : a European journal of chemical biology 2009;10(11):1811-5.
2009: Katada Hitoshi; Komiyama Makoto
Artificial restriction DNA cutters as new tools for gene manipulation.
Chembiochem : a European journal of chemical biology 2009;10(8):1279-88.
2009: Ishizuka Takumi; Otani Kosuke; Sumaoka Jun; Komiyama Makoto
Strand invasion of conventional PNA to arbitrary sequence in DNA assisted by single-stranded DNA binding protein.
Chemical communications (Cambridge, England) 2009;(10):1225-7.
2009: Miyajima Yoshitaka; Ishizuka Takumi; Yamamoto Yoji; Sumaoka Jun; Komiyama Makoto
Origin of high fidelity in target-sequence recognition by PNA-Ce(IV)/EDTA combinations as site-selective DNA cutters.
Journal of the American Chemical Society 2009;131(7):2657-62.
2009: Murakami Taku; Sumaoka Jun; Komiyama Makoto
Sensitive isothermal detection of nucleic-acid sequence by primer generation-rolling circle amplification.
Nucleic acids research 2009;37(3):e19.
2009: Xu Yan; Ishizuka Takumi; Kurabayashi Kaori; Komiyama Makoto
Consecutive formation of G-quadruplexes in human telomeric-overhang DNA: a protective capping structure for telomere ends.
Angewandte Chemie (International ed. in English) 2009;48(42):7833-6.
2009: Kimura Takashi; Xu Yan; Komiyama Makoto
Human telomeric RNA r(UAGGGU) sequence forms parallel tetraplex structure with U-quartet.
Nucleic acids symposium series (2004) 2009;(53):239-40.
2009: Aiba Yuichiro; Komiyama Makoto
Handy and prompt DNA separation using PNA with internal disulfide bond.
Nucleic acids symposium series (2004) 2009;(53):175-6.
2009: Ishizuka Takumi; Sforza Stefano; Komiyama Makoto
Promotion of strand invasion by utilizing entropically-favored PNA.
Nucleic acids symposium series (2004) 2009;(53):161-2.
2009: Kuzuya Akinori; Tanaka Keita; Katada Hitoshi; Komiyama Makoto
Restriction enzyme treatment/ligation independent cloning using caged primers for PCR.
Nucleic acids symposium series (2004) 2009;(53):75-6.
2009: Xu Yan; Suzuki Yuta; Kaminaga Kuniyuki; Komiyama Makoto
Molecular basis of human telomere DNA/RNA structure and its potential application.
Nucleic acids symposium series (2004) 2009;(53):63-4.
2009: Xu Yan; Suzuki Yuta; Komiyama Makoto
Click chemistry for the identification of G-quadruplex structures: discovery of a DNA-RNA G-quadruplex.
Angewandte Chemie (International ed. in English) 2009;48(18):3281-4.
2009: Chen Jing; Serizawa Takeshi; Komiyama Makoto
Peptides recognize photoresponsive targets.
Angewandte Chemie (International ed. in English) 2009;48(16):2917-20.
2008: Tanaka Keita; Yamamoto Yoji; Kuzuya Akinori; Komiyama Makoto
Synthesis of photo-responsive acridine-modified DNA and its application to site-selective RNA scission.
Nucleosides, nucleotides & nucleic acids 2008;27(10):1175-85.
2008: Tanaka Keita; Katada Hitoshi; Shigi Narumi; Kuzuya Akinori; Komiyama Makoto
Site-selective blocking of PCR by a caged nucleotide leading to direct creation of desired sticky ends in the products.
Chembiochem : a European journal of chemical biology 2008;9(13):2120-6.
2008: Xu Yan; Kaminaga Kuniyuki; Komiyama Makoto
G-quadruplex formation by human telomeric repeats-containing RNA in Na+ solution.
Journal of the American Chemical Society 2008;130(33):11179-84.
2008: Ishizuka Takumi; Yoshida Junya; Yamamoto Yoji; Sumaoka Jun; Tedeschi Tullia; Corradini Roberto; Sforza Stefano; Komiyama Makoto
Chiral introduction of positive charges to PNA for double-duplex invasion to versatile sequences.
Nucleic acids research 2008;36(5):1464-71.
2008: Katada Hitoshi; Seino Hidetake; Mizobe Yasushi; Sumaoka Jun; Komiyama Makoto
Crystal structure of Ce(IV)/dipicolinate complex as catalyst for DNA hydrolysis.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2008;13(2):249-55.
2008: Kuzuya Akinori; Numajiri Kentaro; Kimura Mayumi; Komiyama Makoto
Single-molecule accommodation of streptavidin in nanometer-scale wells formed in DNA nanostructures.
Nucleic acids symposium series (2004) 2008;(52):681-2.
2008: Katada Hitoshi; Ren Yi; Shigi Narumi; Komiyama Makoto
Site-specific gene manipulation of fluorescent proteins using artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2008;(52):483-4.
2008: Tanaka Keita; Katada Hitoshi; Shigi Narumi; Kuzuya Akinori; Komiyama Makoto
Direct preparation of sticky-ended duplexes within PCR by using caged primers.
Nucleic acids symposium series (2004) 2008;(52):467-8.
2008: Suzuki Yuta; Lönnberg Tuomas; Komiyama Makoto
Hydrolysis of single linkage in long DNA using oligonucleotide-multiphosphonate conjugates and Ce IV/EDTA.
Nucleic acids symposium series (2004) 2008;(52):379-80.
2008: Xu Yan; Kaminaga Kuniyuki; Komiyama Makoto
Human telomeric RNA in G-quadruplex structure.
Nucleic acids symposium series (2004) 2008;(52):175-6.
2008: Xu Yan; Kimura Takashi; Komiyama Makoto
Human telomere RNA and DNA form an intermolecular G-quadruplex.
Nucleic acids symposium series (2004) 2008;(52):169-70.
2008: Aiba Yuichiro; Komiyama Makoto
Introduction of linkers into PNA for versatile applications.
Nucleic acids symposium series (2004) 2008;(52):143-4.
2008: Ishizuka Takumi; Komiyama Makoto
Single-strand binding protein enhances invasion of a PNA strand to double-stranded DNA.
Nucleic acids symposium series (2004) 2008;(52):141-2.
2008: Miyajima Yoshitaka; Ishizuka Takumi; Komiyama Makoto
Mismatch recognition in PNA double-duplex invasion.
Nucleic acids symposium series (2004) 2008;(52):125-6.
2008: Komiyama Makoto; Aiba Yuichiro; Yamamoto Yoji; Sumaoka Jun
Artificial restriction DNA cutter for site-selective scission of double-stranded DNA with tunable scission site and specificity.
Nature protocols 2008;3(4):655-62.
2008: Komiyama Makoto; Aiba Yuichiro; Ishizuka Takumi; Sumaoka Jun
Solid-phase synthesis of pseudo-complementary peptide nucleic acids.
Nature protocols 2008;3(4):646-54.
2008: Kuzuya Akinori; Numajiri Kentaro; Komiyama Makoto
Accommodation of a single protein guest in nanometer-scale wells embedded in a "DNA nanotape".
Angewandte Chemie (International ed. in English) 2008;47(18):3400-2.
2007: Tedeschi Tullia; Sforza Stefano; Ye Sheng; Corradini Roberto; Dossena Arnaldo; Komiyama Makoto; Marchelli Rosangela
Fast and easy colorimetric tests for single mismatch recognition by PNA-DNA duplexes with the diethylthiadicarbocyanine dye and succinyl-beta-cyclodextrin.
Journal of biochemical and biophysical methods 2007;70(5):735-41.
2007: Ye Sheng; Miyajima Yoshitaka; Ohnishi Toshiyuki; Yamamoto Yoji; Komiyama Makoto
Combination of peptide nucleic acid beacon and nuclease S1 for clear-cut genotyping of single nucleotide polymorphisms.
Analytical biochemistry 2007;363(2):300-2.
2007: Yamamoto Yoji; Uehara Akihiko; Miura Kazuyuki; Watanabe Akira; Aburatani Hiroyuki; Komiyama Makoto
Development of artificial restriction DNA cutter composed of Ce(Iv)/EDTA and PNA.
Nucleosides, nucleotides & nucleic acids 2007;26(10-12):1265-8.
2007: Kuzuya Akinori; Komiyama Makoto
A robust DNA framework for single molecule observation with atomic force microscope.
Nucleic acids symposium series (2004) 2007;(51):331-2.
2007: Miyajima Yoshitaka; Yamamoto Yoji; Komiyama Makoto
Promotion of PNA double-duplex invasion by glutaric dialdehyde.
Nucleic acids symposium series (2004) 2007;(51):271-2.
2007: Xu Yan; Sato Hiroyuki; Shinohara Ken-Ichi; Komiyama Makoto; Sugiyama Hiroshi
T-loop formation by human telomeric G-quadruplex.
Nucleic acids symposium series (2004) 2007;(51):243-4.
2007: Xu Yan; Komiyama Makoto
The structural studies of human telomeric DNA using AFM.
Nucleic acids symposium series (2004) 2007;(51):241-2.
2007: Tanaka Keita; Yamamoto Yoji; Kuzuya Akinori; Komiyama Makoto
Photocontrol of site-selective RNA scission.
Nucleic acids symposium series (2004) 2007;(51):205-6.
2007: Xu Yan; Hirohata Youhei; Komiyama Makoto
Sequence-specific cleavage of human telomere DNA by G-quadruplex formation.
Nucleic acids symposium series (2004) 2007;(51):199-200.
2007: Shigi Narumi; Otani Kosuke; Komiyama Makoto
Gene manipulation of adenovirus vector by artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2007;(51):197-8.
2007: Lönnberg Tuomas; Suzuki Yuta; Komiyama Makoto
Ce(IV)-catalyzed site-selective DNA hydrolysis using tris- and tetrakismethylenephosphonate-modified oligonucleotides.
Nucleic acids symposium series (2004) 2007;(51):195-6.
2007: Yamamoto Yoji; Mori Masao; Aiba Yuichiro; Tomita Takafumi; Chen Wen; Zhou Jing-Min; Uehara Akihiko; Ren Yi; Kitamura Yoshihito; Komiyama Makoto
Chemical modification of Ce(IV)/EDTA-based artificial restriction DNA cutter for versatile manipulation of double-stranded DNA.
Nucleic acids research 2007;35(7):e53.
2006: Sato Aya; Watanabe Yoh-ichi; Suzuki Tsutomu; Komiyama Makoto; Watanabe Kimitsuna; Ohtsuki Takashi
Identification of the residues involved in the unique serine specificity of Caenorhabditis elegans mitochondrial EF-Tu2.
Biochemistry 2006;45(36):10920-7.
2006: Kashida Hiromu; Asanuma Hiroyuki; Komiyama Makoto
Insertion of two pyrene moieties into oligodeoxyribonucleotides for the efficient detection of deletion polymorphisms.
Chemical communications (Cambridge, England) 2006;(26):2768-70.
2006: Yamamoto Yoji; Uehara Akihiko; Watanabe Akira; Aburatani Hiroyuki; Komiyama Makoto
Chemical-reaction-based site-selective DNA cutter for PCR-free gene manipulation.
Chembiochem : a European journal of chemical biology 2006;7(4):673-7.
2006: Liu Mingzhe; Asanuma Hiroyuki; Komiyama Makoto
Azobenzene-tethered T7 promoter for efficient photoregulation of transcription.
Journal of the American Chemical Society 2006;128(3):1009-15.
2006: Kitamura Yoshihito; Mori Satoshi; Chen Wen; Sumaoka Jun; Komiyama Makoto
Recombination of the GFP gene to the BFP gene using a man-made site-selective DNA cutter.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2006;11(1):13-6.
2006: Sasayama Takuro; Kato Mayu; Aburatani Hiroyuki; Kuzuya Akinori; Komiyama Makoto
Simultaneous genotyping of indels and SNPs by mass spectroscopy.
Journal of the American Society for Mass Spectrometry 2006;17(1):3-8.
2006: Kashida Hiromu; Tanaka Masayuki; Baba Seiki; Sakamoto Taiichi; Kawai Gota; Asanuma Hiroyuki; Komiyama Makoto
Covalent incorporation of methyl red dyes into double-stranded DNA for their ordered clustering.
Chemistry (Weinheim an der Bergstrasse, Germany) 2006;12(3):777-84.
2006: Pan Fenggang; Sumaoka Jun; Hirano Toshiyuki; Okutsu Yoshitaka; Takeuchi Osamu; Shigekawa Hidemi; Komiyama Makoto
Fabrication of Au-DNA-Au nanostructure with new-type DNA-Au conjugate.
Nucleic acids symposium series (2004) 2006;(50):317-8.
2006: Yamamoto Yoji; Kimura Mayumi; Kato Mayu; Kuzuya Akinori; Komiyama Makoto
Site-selective RNA scission by PNA-Lu(III) hybrid system.
Nucleic acids symposium series (2004) 2006;(50):267-8.
2006: Yamamoto Yoji; Miura Kazuyuki; Komiyama Makoto
Site-selective hydrolysis of huge DNA by artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2006;(50):265-6.
2006: Aiba Yuichiro; Yamamoto Yoji; Komiyama Makoto
Highly active artificial restriction enzyme composed of Ce(IV)/EDTA and PNA bearing phosphate group--relationship between the promotion by phosphate and the structure of invasion complex.
Nucleic acids symposium series (2004) 2006;(50):255-6.
2006: Yamamoto Yoji; Yoshida Junya; Tedeschi Tullia; Corradini Roberto; Sforza Stefano; Komiyama Makoto
Highly efficient strand invasion by peptide nucleic acid bearing optically pure lysine residues in its backbone.
Nucleic acids symposium series (2004) 2006;(50):109-10.
2006: Sumaoka Jun; Furuki Kenichiro; Kojima Yuki; Shibata Masahiko; Hirao Kimihiko; Takeda Naoya; Komiyama Makoto
Active species for Ce(IV)-induced hydrolysis of phosphodiester linkage in cAMP and DNA.
Nucleosides, nucleotides & nucleic acids 2006;25(4-6):523-38.
2005: Chen Wen; Komiyama Makoto
Site-selective DNA hydrolysis by Ce(IV)-EDTA with the use of one oligonucleotide additive bearing two monophosphates.
Chembiochem : a European journal of chemical biology 2005;6(10):1825-30.
2005: Kuzuya Akinori; Shi Yun; Sasayama Takuro; Komiyama Makoto
Cooperation of metal-ion fixation and target-site activation for efficient site-selective RNA scission.
Journal of biological inorganic chemistry : JBIC : a publication of the Society of Biological Inorganic Chemistry 2005;10(3):270-4.
2005: Shi Yun; Machida Kenzo; Kuzuya Akinori; Komiyama Makoto
Design of phosphoramidite monomer for optimal incorporation of functional intercalator to main chain of oligonucleotide.
Bioconjugate chemistry 2005;16(2):306-11.
2005: Komiyama Makoto; Arishima Hiroyuki; Yokoyama Masahito; Kitamura Yoshihito; Yamamoto Yoji
Oligonucleotide bearing ethylenediamine-N,N,N'-Triacetates for gap-selective DNA hydrolysis by Ce4+/EDTA.
Chembiochem : a European journal of chemical biology 2005;6(1):192-6.
2005: Liu Mingzhe; Komiyama Makoto; Asanuma Hiroyuki
Design of light-switchable phage promoter for efficient photo-regulation of gene-expression.
Nucleic acids symposium series (2004) 2005;(49):283-4.
2005: Kitamura Yoshihito; Mori Satoshi; Komiyama Makoto
Gene manipulation of fluorescent protein through site-selective hydrolysis by Ce(IV)/EDTA.
Nucleic acids symposium series (2004) 2005;(49):281-2.
2005: Uehara Akihiko; Yamamoto Yoji; Watanabe Akira; Aburatani Hiroyuki; Komiyama Makoto
Construction of chimera protein by using artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2005;(49):279-80.
2005: Aiba Yuichiro; Mori Masao; Yamamoto Yoji; Komiyama Makoto
Rapid site-selective hydrolysis of double-stranded DNA by use of Ce(IV)/EDTA and PNA bearing phosphate group.
Nucleic acids symposium series (2004) 2005;(49):277-8.
2005: Zhou Jing-Min; Yamamoto Yoji; Uehara Akihiko; Komiyama Makoto
Genetic recombination without using either restriction enzyme or PCR.
Nucleic acids symposium series (2004) 2005;(49):259-60.
2005: Yamamoto Yoji; Zhou Jing-Min; Tomita Takafumi; Uehara Akihiko; Aiba Yuichiro; Watanabe Akira; Aburatani Hiroyuki; Komiyama Makoto
Gene manipulation using artificial restriction DNA cutter.
Nucleic acids symposium series (2004) 2005;(49):73-4.
2004: Kashida Hiromu; Asanuma Hiroyuki; Komiyama Makoto
Alternating hetero H aggregation of different dyes by interstrand stacking from two DNA-dye conjugates.
Angewandte Chemie (International ed. in English) 2004;43(47):6522-5.
2004: Matsunaga Daijiro; Asanuma Hiroyuki; Komiyama Makoto
Photoregulation of RNA digestion by RNase H with azobenzene-tethered DNA.
Journal of the American Chemical Society 2004;126(37):11452-3.
2004: Chen Wen; Kitamura Yoshihito; Zhou Jing-Min; Sumaoka Jun; Komiyama Makoto
Site-selective DNA hydrolysis by combining Ce(IV)/EDTA with monophosphate-bearing oligonucleotides and enzymatic ligation of the scission fragments.
Journal of the American Chemical Society 2004;126(33):10285-91.
2004: Yashiro Morio; Kaneiwa Hideki; Onaka Kenichi; Komiyama Makoto
Dinuclear Zn2+ complexes in the hydrolysis of the phosphodiester linkage in a diribonucleoside monophosphate diester.
Dalton transactions (Cambridge, England : 2003) 2004;(4):605-10.
2004: Kuzuya Akinori; Mizoguchi Ryo; Sasayama Takuro; Zhou Jing-Min; Komiyama Makoto
Selective activation of two sites in RNA by acridine-bearing oligonucleotides for clipping of designated RNA fragments.
Journal of the American Chemical Society 2004;126(5):1430-6.
2004: Nomura Yasuo; Kubozono Takayasu; Hidaka Makoto; Horibe Mineko; Mizushima Naoki; Yamamoto Nobuyuki; Takahashi Toshio; Komiyama Makoto
Predominant role of basicity of leaving group in alpha-effect for nucleophilic ester cleavage.
Bioorganic chemistry 2004;32(1):26-37.
2004: Yamamoto Yoji; Mori Masao; Tomita Takafumi; Zhou Jing-Min; Komiyama Makoto
Manipulation of double-stranded DNA by artificial restriction enzyme composed of Ce(IV)/EDTA and PNA.
Nucleic acids symposium series (2004) 2004;(48):279-80.
2004: Liu Mingzhe; Asanuma Hiroyuki; Komiyama Makoto
Real time monitoring of the interaction of T7 RNA polymerase with azobenzene-tethered T7 promoter by biosensor.
Nucleic acids symposium series (2004) 2004;(48):221-2.
2004: Shi Yun; Machida Kenzo; Kuzuya Akinori; Komiyama Makoto
Simultaneous use of highly acidic acridine and rigid chiral linker for efficient site-selective RNA scission.
Nucleic acids symposium series (2004) 2004;(48):219-20.
2004: Zhao Jing; Zhou Jingmin; Liu Mingzhe; Asanuma Hiroyuki; Komiyama Makoto
Photoregulation of in vitro transcription/translation of GFP by tethering an azobenzene to T7 promoter.
Nucleic acids symposium series (2004) 2004;(48):199-200.
2004: Ren Binzhi; Komiyama Makoto
High-throughput SNP genotyping by combining exonuclease III, nuclease S1, and acridine-bearing PNA.
Nucleic acids symposium series (2004) 2004;(48):183-4.
2004: Kitamura Yoshihito; Yoshida Junya; Chen Wen; Zhou Jing-Min; Sumaoka Jun; Komiyama Makoto
Manipulation of DNA through Ce(IV)/EDTA-induced site-selective hydrolysis using phosphate-bearing oligonucleotides.
Nucleic acids symposium series (2004) 2004;(48):151-2.
2004: Yamamoto Yoji; Komiyama Makoto
Combination of S1 nuclease and PNA for site-selective hydrolysis of double-stranded DNA. Comparison with the site-selective hydrolysis using Ce(IV)/EDTA.
Nucleic acids symposium series (2004) 2004;(48):149-50.
2004: Yamamoto Yoji; Uehara Akihiko; Tomita Takafumi; Komiyama Makoto
Site-selective and hydrolytic two-strand scission of double-stranded DNA using Ce(IV)/EDTA and pseudo-complementary PNA.
Nucleic acids research 2004;32(19):e153.
2004: Ren Binzhi; Zhou Jing-Min; Komiyama Makoto
Straightforward detection of SNPs in double-stranded DNA by using exonuclease III/nuclease S1/PNA system.
Nucleic acids research 2004;32(4):e42.
2003: Liang Xingguo; Asanuma Hiroyuki; Kashida Hiromu; Takasu Akitsugu; Sakamoto Taiichi; Kawai Gota; Komiyama Makoto
NMR study on the photoresponsive DNA tethering an azobenzene. Assignment of the absolute configuration of two diastereomers and structure determination of their duplexes in the trans-form.
Journal of the American Chemical Society 2003;125(52):16408-15.
2003: Yamamoto Yoji; Tsuboi Wataru; Komiyama Makoto
Oligoamine-acridine conjugates for promotion of gap-selective DNA hydrolysis by Ce(IV)/EDTA complex.
Nucleic acids research 2003;31(15):4497-502.
2003: Asanuma Hiroyuki; Kashida Hiromu; Liang Xingguo; Komiyama Makoto
DNA-Naphthyl Red conjugate as a visualizing probe of DNA hybridization.
Chemical communications (Cambridge, England) 2003;(13):1536-7.
2003: Miyake Koji; Yasuda Satoshi; Harada Akira; Sumaoka Jun; Komiyama Makoto; Shigekawa Hidemi
Formation process of cyclodextrin necklace-analysis of hydrogen bonding on a molecular level.
Journal of the American Chemical Society 2003;125(17):5080-5.
2003: Komiyama Makoto; Ye Sheng; Liang Xingguo; Yamamoto Yoji; Tomita Takafumi; Zhou Jing-Min; Aburatani Hiroyuki
PNA for one-base differentiating protection of DNA from nuclease and its use for SNPs detection.
Journal of the American Chemical Society 2003;125(13):3758-62.
2003: Kuzuya Akinori; Mizoguchi Ryo; Morisawa Fumi; Komiyama Makoto
Site-selective RNA scission at two sites for precise genotyping of SNPs by mass spectrometry.
Chemical communications (Cambridge, England) 2003;(6):770-1.
2003: Yashiro Morio; Sonobe Yoko; Yamamura Ai; Takarada Tohru; Komiyama Makoto; Fujii Yuki
Metal-ion-assisted hydrolysis of dipeptides involving a serine residue in a neutral aqueous solution.
Organic & biomolecular chemistry 2003;1(4):629-32.
2003: Asanuma Hiroyuki; Shirasuka Kenji; Takarada Tohru; Kashida Hiromu; Komiyama Makoto
DNA-dye conjugates for controllable H aggregation(1).
Journal of the American Chemical Society 2003;125(8):2217-23.
2003: Liu Mingzhe; Asanuma Hiroyuki; Komiyama Makoto
Effective photo-regulation of transcription reaction by SP6 RNA polymerase with modified DNA tethering multiple azobenzenes.
Nucleic acids research. Supplement (2001) 2003;(3):265-6.
2003: Ye Sheng; Liang Xingguo; Yamamoto Yoji; Zhou Jing-Min; Tomita Takafumi; Aburatani Hiroyuki; Komiyama Makoto
Simultaneous detection of multiple single nucleotide polymorphism by single-strand-specific nuclease and PNA probe.
Nucleic acids research. Supplement (2001) 2003;(3):185-6.
2003: Kuzuya Akinori; Mizoguchi Ryo; Sasayama Takuro; Komiyama Makoto
Tandem site-selective RNA scission utilizing acridine-DNA conjugates.
Nucleic acids research. Supplement (2001) 2003;(3):167-8.
2003: Kashida Hiromu; Asanuma Hiroyuki; Komiyama Makoto
Development of a probe DNA which accompanies color change on hybridization.
Nucleic acids research. Supplement (2001) 2003;(3):143-4.
2003: Arishima Hiroyuki; Yokoyama Masahito; Komiyama Makoto
Site-selective DNA hydrolysis by the combination of Ce(IV) and oligonucleotide bearing EDTA groups.
Nucleic acids research. Supplement (2001) 2003;(3):137-8.
2003: Asanuma Hiroyuki; Matsunaga Daijiro; Liu Minghe; Liang Xingguo; Jhao Jing; Komiyama Makoto
Photo-regulation of DNA function by azobenzene-tethered oligonucleotides.
Nucleic acids research. Supplement (2001) 2003;(3):117-8.
2003: Komiyama Makoto
Sequence-selective scission of DNA and RNA by lanthanide ions and their complexes.
Metal ions in biological systems 2003;40():463-75.
2003: Komiyama Makoto; Takarada Tohru
Lanthanide-promoted peptide bond hydrolysis.
Metal ions in biological systems 2003;40():355-68.
2002: Komiyama Makoto; Kina Shinichiro; Matsumura Kazunari; Sumaoka Jun; Tobey Suzanne; Lynch Vincent M; Anslyn Eric
Trinuclear copper(II) complex showing high selectivity for the hydrolysis of 2'-5' over 3'-5' for UpU and 3'-5' over 2'-5' for ApA ribonucleotides.
Journal of the American Chemical Society 2002;124(46):13731-6.
2002: Kitamura Yoshihito; Komiyama Makoto
Preferential hydrolysis of gap and bulge sites in DNA by Ce(IV)/EDTA complex.
Nucleic acids research 2002;30(19):e102.
2002: Asanuma Hiroyuki; Tamaru Daisuke; Yamazawa Akira; Liu Mingzhe; Komiyama Makoto
Photoregulation of the transcription reaction of T7 RNA polymerase by tethering an azobenzene to the promoter.
Chembiochem : a European journal of chemical biology 2002;3(8):786-9.
2002: Kuzuya Akinori; Mizoguchi Ryo; Morisawa Fumi; Machida Kenzo; Komiyama Makoto
Metal ion-induced site-selective RNA hydrolysis by use of acridine-bearing oligonucleotide as cofactor.
Journal of the American Chemical Society 2002;124(24):6887-94.
2002: Kuzuya Akinori; Machida Kenzo; Mizoguchi Ryo; Komiyama Makoto
Conjugation of various acridines to DNA for site-selective RNA scission by lanthanide ion.
Bioconjugate chemistry 2002;13(2):365-9.
2002: Liang Xingguo; Asanuma Hiroyuki; Komiyama Makoto
Photoregulation of DNA triplex formation by azobenzene.
Journal of the American Chemical Society 2002;124(9):1877-83.
2002: Hishiya Takayuki; Asanuma Hiroyuki; Komiyama Makoto
Spectroscopic anatomy of molecular-imprinting of cyclodextrin. Evidence for preferential formation of ordered cyclodextrin assemblies.
Journal of the American Chemical Society 2002;124(4):570-5.
2002: Ye Sheng; Liang Xingguo; Yamamoto Yoji; Komiyama Makoto
Detection of single nucleotide polymorphisms by the combination of nuclease S1 and PNA.
Nucleic acids research. Supplement (2001) 2002;(2):235-6.
2002: Kuzuya Akinori; Mizoguchi Ryo; Morisawa Fumi; Komiyama Makoto
Novel approach for SNP genotyping based on site-selective RNA scission.
Nucleic acids research. Supplement (2001) 2002;(2):129-30.
2002: Asanuma Hiroyuki; Liu Mingzhe; Tamaru Daisuke; Liang Xingguo; Komiyama Makoto
Photo-regulation of transcription by RNA polymerase with azobenzene-tethered promoter.
Nucleic acids research. Supplement (2001) 2002;(2):75-6.
2001: Asanuma H; Liang X; Yoshida T; Komiyama M
Photocontrol of DNA duplex formation by using azobenzene-bearing oligonucleotides.
Chembiochem : a European journal of chemical biology 2001;2(1):39-44.
2001: Asanuma H; Shirasuka K; Takarada T; Komiyama M
Regulation of aggregated structure of dye molecules by DNA hybridization.
Nucleic acids research. Supplement (2001) 2001;(1):193-4.
2001: Kuzuya A; Mizoguchi R; Komiyama M
Site-selective artificial ribonuclease using pinpoint RNA activation.
Nucleic acids research. Supplement (2001) 2001;(1):131-2.
2001: Matsumura K; Kina S; Sumaoka J; Tobey S; Anslyn E V; Komiyama M
Trinuclear Cu(II) complex for internucleoside linkage-specific cleavage of RNA.
Nucleic acids research. Supplement (2001) 2001;(1):85-6.
2001: Asanuma H; Tamaru D; Yoshida T; Yamazawa A; Mitsui T; Okuni T; Kimoto M; Hirao I; Yokoyama S; Komiyama M
Photo-regulation of RNA polymerase reaction by use of modified DNA carrying an azobenzene.
Nucleic acids research. Supplement (2001) 2001;(1):55-6.
2001: Komiyama M; Sumaoka J; Kuzuya A; Yamamoto Y
Sequence-selective artificial ribonucleases.
Methods in enzymology 2001;341():455-68.
2001: Komiyama M
Lanthanide ion-mediated peptide hydrolysis.
Metal ions in biological systems 2001;38():25-41.
2000: Takarada T; Yashiro M; Komiyama M
Catalytic hydrolysis of peptides by cerium(IV).
Chemistry (Weinheim an der Bergstrasse, Germany) 2000;6(21):3906-13.
2000: Takeda N; Shibata M; Tajima N; Hirao K; Komiyama M
Kinetic and theoretical studies on the mechanism of alkaline hydrolysis of DNA.
The Journal of organic chemistry 2000;65(14):4391-6.
2000: Igawa T; Sumaoka J; Komiyama M
Kinetic studies on Ce(IV)-induced hydrolysis of single-stranded and double-stranded oligonucleotides.
Nucleosides, nucleotides & nucleic acids 2000;19(5-6):891-902.
2000: Liang X; Yoshida T; Asanuma H; Komiyama M
Photo-regulation of DNA/RNA duplex formation by azobenzene-tethered DNA towards antisense strategy.
Nucleic acids symposium series 2000;(44):277-8.
2000: Yamamoto Y; Igawa T; Sumaoka J; Komiyama M
Hydrolysis of DNA by Ce(IV)/EDTA complexes--the mechanism of DNA cleavage and design of artificial restriction enzymes.
Nucleic acids symposium series 2000;(44):231-2.
1999: Igawa T; Sumaoka J; Komiyama M
Improvement of efficiency of the Ce(IV)-induced DNA scission--relationship between the kinetic parameters (k(cat) and Km) and the DNA structure.
Nucleic acids symposium series 1999;(42):231-2.
1999: Asanuma H; Liang X; Yoshida T; Ito T; Komiyama M
Photo-regulated duplex- and triplex-formation of the modified DNA carrying azobenzene.
Nucleic acids symposium series 1999;(42):135-6.
1998: Komiyama M; Sumaoka J
Progress towards synthetic enzymes for phosphoester hydrolysis.
Current opinion in chemical biology 1998;2(6):751-7.
1997: Matsumura K; Komiyama M
Enormously fast RNA hydrolysis by lanthanide(III) ions under physiological conditions: eminent candidates for novel tools of biotechnology.
Journal of biochemistry 1997;122(2):387-94.
1997: Takeda N; Okada Y; Yashiro M; Komiyama M
Non-enzymatic hydrolyses of aryl esters of thymidine 3'-monophosphate as probes for the rate-determining step in DNA hydrolysis.
Nucleic acids symposium series 1997;(37):263-4.
1997: Takarada T; Yamamura A; Yashiro M; Komiyama M
Mechanistic analogy between metal ion-catalyzed self-splicing of protein and RNA.
Nucleic acids symposium series 1997;(37):245-6.
1997: Sumaoka J; Kajimura A; Komiyama M
Homogeneous catalyst for DNA hydrolysis (4). Efficient DNA hydrolysis by lanthanide--saccharide complexes.
Nucleic acids symposium series 1997;(37):211-2.
1997: Kuzuya A; Azuma Y; Inokawa T; Yoshinari K; Komiyama M
Sequence-selective RNA scission by oligoamine--DNA conjugates (1).
Nucleic acids symposium series 1997;(37):209-10.
1996: Yashiro M; Ishikubo A; Komiyama M
Dinuclear lanthanum(III) complex for efficient hydrolysis of RNA.
Journal of biochemistry 1996;120(6):1067-9.
1995: Komiyama M
Sequence-specific and hydrolytic scission of DNA and RNA by lanthanide complex-oligoDNA hybrids.
Journal of biochemistry 1995;118(4):665-70.
1995: Komiyama M; Yashiro M
[Molecular design of artificial nucleases]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(10):1438-43.
1995: Komiyama M; Matsumura K; Takarada T
[Hydrolysis of RNA and protein by rare-earth metal ions]
Tanpakushitsu kakusan koso. Protein, nucleic acid, enzyme 1995;40(7):911-7.
1995: Irisawa M; Komiyama M
Hydrolysis of DNA and RNA through cooperation of two metal ions: a novel mimic of phosphoesterases.
Journal of biochemistry 1995;117(3):465-6.
1995: Takeda N; Irisawa M; Imai T; Yashiro M; Komiyama M
Synergism of Ce (IV) and Pr(III) for the fastest non-enzymatic DNA hydrolysis ever.
Nucleic acids symposium series 1995;(34):207-8.
1995: Endo M; Hirata K; Inokawa T; Matsumura K; Komiyama M; Ihara T; Sueda S; Takagi M
Site-specific hydrolysis of yeast tRNAPhe by anthraquinone-glycine and anthraquinone-iminodiacetate conjugates.
Nucleic acids symposium series 1995;(34):109-10.
1995: Ishikubo A; Yashiro M; Komiyama M
Dinuclear metal complexes for the efficient RNA hydrolysis.
Nucleic acids symposium series 1995;(34):85-6.
1995: Sumaoka J; Uchida H; Komiyama M
Acetylacetonato-lanthanide complexes as eminent catalytic sites for artificial ribonucleases.
Nucleic acids symposium series 1995;(34):83-4.
1994: Komiyama M; Inokawa T
Selective hydrolysis of tRNA by ethylenediamine bound to a DNA oligomer.
Journal of biochemistry 1994;116(4):719-20.
1994: Yajima H; Sumaoka J; Miyama S; Komiyama M
Lanthanide ions for the first non-enzymatic formation of adenosine 3',5'-cyclic monophosphate from adenosine triphosphate under physiological conditions.
Journal of biochemistry 1994;115(6):1038-9.
1994: Komiyama M; Kodama T; Takeda N; Sumaoka J; Shiiba T; Matsumoto Y; Yashiro M
Catalytically active species for CeCl3-induced DNA hydrolysis.
Journal of biochemistry 1994;115(5):809-10.
1993: Sawata S; Shimayama T; Komiyama M; Kumar P K; Nishikawa S; Taira K
Enhancement of the cleavage rates of DNA-armed hammerhead ribozymes by various divalent metal ions.
Nucleic acids research 1993;21(24):5656-60.
1993: Komiyama M; Inokawa T; Shiiba T; Takeda N; Yoshinari K; Yashiro M
Molecular design of artificial hydrolytic nucleases and ribonucleases.
Nucleic acids symposium series 1993;(29):197-8.
1992: Sumaoka J; Yashiro M; Komiyama M
Enormous catalyses of lanthanide metal ions for unprecedentedly fast hydrolysis of 3',5'-cyclic adenosine monophosphate.
Nucleic acids symposium series 1992;(27):37-8.
1992: Kobayashi M; Miyama S; Komiyama M
Oxygen-independent photocleavage of DNA by xanthene dyes.
Nucleic acids symposium series 1992;(27):31-2.
1992: Matsumoto Y; Komiyama M
DNA hydrolysis by rare-earth metal ions.
Nucleic acids symposium series 1992;(27):33-4.
1992: Yoshinari K; Inokawa T; Komiyama M
OligoDNA-oligoamine hybrid for facile and sequence selective hydrolysis of RNA.
Nucleic acids symposium series 1992;(27):47-8.
1992: Shiiba T; Komiyama M
Does RNA hydrolysis involve rate-limiting formation of the pentacoordinate intermediate or rate-limiting decomposition? Phenyl ester of adenosine 3'-phosphate as a novel probe.
Nucleic acids symposium series 1992;(27):39-40.
1992: Shimayama T; Sawata S; Komiyama M; Takagi Y; Tanaka Y; Wada A; Sugimoto N; Rossi J J; Nishikawa F; Nishikawa S
Substitution of non-catalytic stem and loop regions of hammerhead ribozyme with DNA counterparts only increases KM without sacrificing the catalytic step (kcat): a way to improve substrate-specificity.
Nucleic acids symposium series 1992;(27):17-8.
1992: Matsumura K; Matsumoto Y; Komiyama M
Rare earth metal ions for unprecedentedly fast RNA hydrolysis.
Nucleic acids symposium series 1992;(27):11-2.
1991: Kobayashi M; Harada M; Komiyama M
Effective photocleavage of DNA by pheophorbide a.
Nucleic acids symposium series 1991;(25):21-2.
1991: Matsumoto Y; Komiyama M
Cooperation of Co(III) complex and cyclodextrin for prompt and regioselective hydrolysis of ribonucleoside 2',3'-cyclic monophosphates at pH 7.
Nucleic acids symposium series 1991;(25):105-6.
1991: Yoshinari K; Komiyama M
Facile cleavage of RNAs by oligoamines. Correlation between amine structure and catalytic activity.
Nucleic acids symposium series 1991;(25):23-4.
1991: Yonezawa K; Matsumoto Y; Komiyama M
Prompt hydrolysis of adenosine 3', 5'-cyclic monophosphate by Co(III) complexes.
Nucleic acids symposium series 1991;(25):145-6.
1990: Matsumoto Y; Yonezawa K; Komiyama M
Facile cleavage of RNA via phosphodiester linkage fission by Co(III) complex.
Nucleic acids symposium series 1990;(22):59-60.

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