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Paul Komminoth

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Matthias Dettmer; Mary Beth Durso; Paul Komminoth; Holger Moch; Yuri E Nikiforov; Aurel Perren; Alexander Vogetseder; Marina N Nikiforova
MicroRNA expression array identifies novel diagnostic markers for conventional and oncocytic follicular thyroid carcinomas.
Matthias Dettmer; Paul Komminoth; Holger Moch; Anja Schmitt; Hans Steinert; Aurel Perren
Poorly differentiated oncocytic thyroid carcinoma--diagnostic implications and outcome.
Hanna Barmettler; Paul Komminoth; Mathias Schmid; Donat Duerr
Efficacy of Cetuximab in Combination with FOLFIRI in a Patient with KRAS Wild-Type Metastatic Anal Cancer.

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2013: Matthias Dettmer; Mary Beth Durso; Paul Komminoth; Holger Moch; Yuri E Nikiforov; Aurel Perren; Alexander Vogetseder; Marina N Nikiforova
MicroRNA expression array identifies novel diagnostic markers for conventional and oncocytic follicular thyroid carcinomas.
The Journal of clinical endocrinology and metabolism 2013;98(1):E1-7.
2012: Matthias Dettmer; Paul Komminoth; Holger Moch; Anja Schmitt; Hans Steinert; Aurel Perren
Poorly differentiated oncocytic thyroid carcinoma--diagnostic implications and outcome.
Histopathology 2012;60(7):1045-51.
2012: Hanna Barmettler; Paul Komminoth; Mathias Schmid; Donat Duerr
Efficacy of Cetuximab in Combination with FOLFIRI in a Patient with KRAS Wild-Type Metastatic Anal Cancer.
Case reports in oncology 2012;5(2):428-33.
2012: Robert T Jensen; Gregory Kaltsas; Reza Kianmanesh; Paul Komminoth; Ramon Salazar; Alain Sauvanet; Jean-Yves Scoazec; Maria L Brandi; Guillaume Cadiot; Wouter W de Herder
ENETS Consensus Guidelines for the management of patients with digestive neuroendocrine neoplasms: functional pancreatic endocrine tumor syndromes.
Neuroendocrinology 2012;95(2):98-119.
2011: Matthias Dettmer; Andreas Haldemann; Paul Komminoth; Andreas Meili; Holger Moch; Anja Schmitt; Hans Steinert; Aurel Perren
Poorly differentiated thyroid carcinomas: how much poorly differentiated is needed?
The American journal of surgical pathology 2011;35(12):1866-72.
2011: Wegatha Tesfay; Paul Komminoth; Jakob Schneider
Gastrointestinal stromal tumors in Addis Ababa, Ethiopia.
Ethiopian medical journal 2011;49(1):43-50.
2010: Annika Blank; Anja M Schmitt; Esther Korpershoek; Francien van Nederveen; Thomas Rudolph; Nicole Weber; Räto Thomas Strebel; Ronald R de Krijger; Paul Komminoth; Aurel Perren
SDHB loss predicts malignancy in pheochromocytomas/sympathethic paragangliomas, but not through hypoxia signalling.
Endocrine-related cancer 2010;17(4):919-28.
2010: Günter Klöppel; G Rindi; Aurel Perren; Paul Komminoth; David S Klimstra
[The ENETS and UICC TNM classification of neuroendocrine tumors of the gastrointestinal tract and the pancreas: comment].
Der Pathologe 2010;31(5):353-4.
2010: Günter Klöppel; Guido Rindi; Aurel Perren; Paul Komminoth; David S Klimstra
The ENETS and AJCC/UICC TNM classifications of the neuroendocrine tumors of the gastrointestinal tract and the pancreas: a statement.
Virchows Archiv : an international journal of pathology 2010;456(6):595-7.
2010: Beata Kos-Kudła; Dermot O'Toole; Massimo Falconi; David Gross; Günther Klöppel; Anders Sundin; John Ramage; Kjell Oberg; Bertram Wiedenmann; Paul Komminoth; Eric Van Custem; Mohandes Mallath; Mauro Papotti; Martyn Caplin
ENETS consensus guidelines for the management of bone and lung metastases from neuroendocrine tumors.
Neuroendocrinology 2010;91(4):341-50.
2009: Anja M Schmitt; Sonja Schmid; T Rudolph; Martin Anlauf; C Prinz; G Klöppel; Holger Moch; Philipp U Heitz; Paul Komminoth; Aurel Perren
VHL inactivation is an important pathway for the development of malignant sporadic pancreatic endocrine tumors.
Endocrine-related cancer 2009;16(4):1219-27.
2009: Martin Anlauf; Juliane Bauersfeld; Andreas Raffel; Christian A Koch; Tobias Henopp; Ibrahim Alkatout; Anja Schmitt; Achim Weber; Marie-Luise Kruse; Stefan Braunstein; Klaus Kaserer; Michael Brauckhoff; Henning Dralle; Holger Moch; Philipp U Heitz; Paul Komminoth; Wolfram T Knoefel; Aurel Perren; Günter Klöppel
Insulinomatosis: a multicentric insulinoma disease that frequently causes early recurrent hyperinsulinemic hypoglycemia.
The American journal of surgical pathology 2009;33(3):339-46.
2009: Dik J Kwekkeboom; Eric P Krenning; Rachida Lebtahi; Paul Komminoth; Beata Kos-Kudła; Wouter W de Herder; Ursula Plöckinger
ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: peptide receptor radionuclide therapy with radiolabeled somatostatin analogs.
Neuroendocrinology 2009;90(2):220-6.
2009: Günter Klöppel; Anne Couvelard; Aurel Perren; Paul Komminoth; Anne-Marie McNicol; Ola Nilsson; Aldo Scarpa; Jean-Yves Scoazec; Bertram Wiedenmann; Mauro Papotti; Guido Rindi; Ursula Plöckinger
ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prognostic stratification.
Neuroendocrinology 2009;90(2):162-6.
2009: Tobias Henopp; Martin Anlauf; Anja Schmitt; Regina Schlenger; Attila Zalatnai; Anne Couvelard; Philippe Ruszniewski; Klaus-Peter Schaps; Yvonne M H Jonkers; Ernst-Jan M Speel; Natalia S Pellegata; Philipp U Heitz; Paul Komminoth; Aurel Perren; Günter Klöppel
Glucagon cell adenomatosis: a newly recognized disease of the endocrine pancreas.
The Journal of clinical endocrinology and metabolism 2009;94(1):213-7.
2008: Kaspar Z'graggen; Ahmed Guweidhi; Rudolf Steffen; Natascha Potoczna; Ruggero Biral; Frank Walther; Paul Komminoth; Fritz Horber
Severe recurrent hypoglycemia after gastric bypass surgery.
Obesity surgery 2008;18(8):981-8.
2008: Nele Garbrecht; Martin Anlauf; Anja Schmitt; Tobias Henopp; Bence Sipos; Andreas Raffel; Claus F Eisenberger; Wolfram T Knoefel; Marianne Pavel; Christian Fottner; Thomas J Musholt; Anja Rinke; Rudolf Arnold; Uta Berndt; Ursula Plöckinger; Bertram Wiedenmann; Holger Moch; Philipp U Heitz; Paul Komminoth; Aurel Perren; Günter Klöppel
Somatostatin-producing neuroendocrine tumors of the duodenum and pancreas: incidence, types, biological behavior, association with inherited syndromes, and functional activity.
Endocrine-related cancer 2008;15(1):229-41.
2008: Anja M Schmitt; Florian Riniker; Martin Anlauf; Sonja Schmid; Alex Soltermann; Holger Moch; Philipp U Heitz; Günther Klöppel; Paul Komminoth; Aurel Perren
Islet 1 (Isl1) expression is a reliable marker for pancreatic endocrine tumors and their metastases.
The American journal of surgical pathology 2008;32(3):420-5.
2008: John K Ramage; Peter E Goretzki; Riccardo Manfredi; Paul Komminoth; Diego Ferone; Rudolf Hyrdel; Gregory Kaltsas; Fahrettin Kelestimur; Larry K Kvols; Jean-Yves Scoazec; M I Sevilla Garcia; Martyn E Caplin
Consensus guidelines for the management of patients with digestive neuroendocrine tumours: well-differentiated colon and rectum tumour/carcinoma.
Neuroendocrinology 2008;87(1):31-9.
2007: Anja M Schmitt; Martin Anlauf; Valentin Rousson; Sonja Schmid; Andreas Kofler; Florian Riniker; Juliane Bauersfeld; Andre Barghorn; Nicole M Probst-Hensch; Holger Moch; Philipp U Heitz; Guenter Kloeppel; Paul Komminoth; Aurel Perren
WHO 2004 criteria and CK19 are reliable prognostic markers in pancreatic endocrine tumors.
The American journal of surgical pathology 2007;31(11):1677-82.
2007: Aurel Perren; Martin Anlauf; Paul Komminoth
Molecular profiles of gastroenteropancreatic endocrine tumors.
Virchows Archiv : an international journal of pathology 2007;451 Suppl 1():S39-46.
2007: Martin Anlauf; Nele Garbrecht; Juliane Bauersfeld; Anja Schmitt; Tobias Henopp; Paul Komminoth; Philipp U Heitz; Aurel Perren; Günter Klöppel
Hereditary neuroendocrine tumors of the gastroenteropancreatic system.
Virchows Archiv : an international journal of pathology 2007;451 Suppl 1():S29-38.
2007: Günter Klöppel; Guido Rindi; Martin Anlauf; Aurel Perren; Paul Komminoth
Site-specific biology and pathology of gastroenteropancreatic neuroendocrine tumors.
Virchows Archiv : an international journal of pathology 2007;451 Suppl 1():S9-27.
2007: Alex Soltermann; Stephan Koetzer; Franz Eigenmann; Paul Komminoth
Correlation of Helicobacter pylori virulence genotypes vacA and cagA with histological parameters of gastritis and patient's age.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2007;20(8):878-83.
2007: Esther Korpershoek; Bart-Jeroen Petri; Francien H van Nederveen; Winand N M Dinjens; Albert A J Verhofstad; Wouter W de Herder; Sonja Schmid; Aurel Perren; Paul Komminoth; Ronald R de Krijger
Candidate gene mutation analysis in bilateral adrenal pheochromocytoma and sympathetic paraganglioma.
Endocrine-related cancer 2007;14(2):453-62.
2007: Martin Anlauf; Aurel Perren; Tobias Henopp; T Rudolf; Nele Garbrecht; Anja Schmitt; Andreas Raffel; Oliver Gimm; Eberhard Weihe; Wolfram T Knoefel; Henning Dralle; Philipp U Heitz; Paul Komminoth; Günter Klöppel
Allelic deletion of the MEN1 gene in duodenal gastrin and somatostatin cell neoplasms and their precursor lesions.
Gut 2007;56(5):637-44.
2007: Aurel Perren; Martin Anlauf; Tobias Henopp; Thomas Rudolph; Anja Schmitt; Andreas Raffel; Oliver Gimm; Eberhard Weihe; Wolfram T Knoefel; Henning Dralle; Philipp U Heitz; Paul Komminoth; Günter Klöppel
Multiple endocrine neoplasia type 1 (MEN1): loss of one MEN1 allele in tumors and monohormonal endocrine cell clusters but not in islet hyperplasia of the pancreas.
The Journal of clinical endocrinology and metabolism 2007;92(3):1118-28.
2006: Martin Anlauf; Nele Garbrecht; Tobias Henopp; Anja Schmitt; Regina Schlenger; Andreas Raffel; Markus Krausch; Oliver Gimm; Claus F Eisenberger; Wolfram T Knoefel; Henning Dralle; Paul Komminoth; Philipp U Heitz; Aurel Perren; Günter Klöppel
Sporadic versus hereditary gastrinomas of the duodenum and pancreas: distinct clinico-pathological and epidemiological features.
World journal of gastroenterology : WJG 2006;12(34):5440-6.
2006: Anja Schmitt; Parvin Saremaslani; Sonja Schmid; V Rousson; matteo montani; Daniel M Schmid; Philipp U Heitz; Paul Komminoth; Aurel Perren
IGFII and MIB1 immunohistochemistry is helpful for the differentiation of benign from malignant adrenocortical tumours.
Histopathology 2006;49(3):298-307.
2006: Esther Korpershoek; Francien H van Nederveen; Hilde Dannenberg; Bart-Jeroen Petri; Paul Komminoth; Aurel Perren; Jacques W M Lenders; Albert A J Verhofstad; Wouter W de Herder; Ronald R de Krijger; Winand N M Dinjens
Genetic analyses of apparently sporadic pheochromocytomas: the Rotterdam experience.
Annals of the New York Academy of Sciences 2006;1073():138-48.
2006: Aurel Perren; Peter Wiesli; Sonja Schmid; matteo montani; Anja Schmitt; Christoph Schmid; Holger Moch; Paul Komminoth
Pancreatic endocrine tumors are a rare manifestation of the neurofibromatosis type 1 phenotype: molecular analysis of a malignant insulinoma in a NF-1 patient.
The American journal of surgical pathology 2006;30(8):1047-51.
2006: Francien H van Nederveen; Aurel Perren; Hilde Dannenberg; Bart-Jeroen Petri; Winand N M Dinjens; Paul Komminoth; Ronald R de Krijger
PTEN gene loss, but not mutation, in benign and malignant phaeochromocytomas.
The Journal of pathology 2006;209(2):274-80.
2006: Martin Anlauf; Regina Schlenger; Aurel Perren; Juliane Bauersfeld; Christian A Koch; Henning Dralle; Andreas Raffel; Wolfram T Knoefel; Eberhard Weihe; Philippe Ruszniewski; Anne Couvelard; Paul Komminoth; Philipp U Heitz; Günter Klöppel
Microadenomatosis of the endocrine pancreas in patients with and without the multiple endocrine neoplasia type 1 syndrome.
The American journal of surgical pathology 2006;30(5):560-74.
2006: Aurel Perren; Paul Komminoth
Familial pheochromocytomas and paragangliomas: stories from the sign-out room.
Endocrine pathology 2006;17(4):337-44.
2006: Philippe Ruszniewski; Gianfranco Delle Fave; Guillaume Cadiot; Paul Komminoth; Daniel Chung; Beata Kos-Kudla; Reza Kianmanesh; David Hochhauser; Rudolf Arnold; Håkan Ahlman; Stanislas Pauwels; Dik J Kwekkeboom; Guido Rindi
Well-differentiated gastric tumors/carcinomas.
Neuroendocrinology 2006;84(3):158-64.
2006: Ernst J M Speel; Anton H N Hopman; Paul Komminoth
Tyramide signal amplification for DNA and mRNA in situ hybridization.
Methods in molecular biology (Clifton, N.J.) 2006;326():33-60.
2005: matteo montani; Anja M Schmitt; Sonja Schmid; Tamara Locher; Parvin Saremaslani; Philipp U Heitz; Paul Komminoth; Aurel Perren
No mutations but an increased frequency of SDHx polymorphisms in patients with sporadic and familial medullary thyroid carcinoma.
Endocrine-related cancer 2005;12(4):1011-6.
2005: Y M H Jonkers; S M H Claessen; Aurel Perren; Sonja Schmid; Paul Komminoth; Albert A J Verhofstad; Leo Hofland; Ronald R de Krijger; P J Slootweg; Frans C S Ramaekers; Ernst J M Speel
Chromosomal instability predicts metastatic disease in patients with insulinomas.
Endocrine-related cancer 2005;12(2):435-47.
2005: Alex Soltermann; Aurel Perren; Sonja Schmid; Franz Eigenmann; Rudolf Güller; Kurt B Weber; Jürg Meier; Peter Eichenberger; Paul Komminoth
Assessment of Helicobacter pylori clarithromycin resistance mutations in archival gastric biopsy samples.
Swiss medical weekly 2005;135(21-22):327-32.
2005: Martin Anlauf; Aurel Perren; Cora Lu Meyer; Sonja Schmid; Parvin Saremaslani; Marie-Luise Kruse; Eberhard Weihe; Paul Komminoth; Philipp U Heitz; Günter Klöppel
Precursor lesions in patients with multiple endocrine neoplasia type 1-associated duodenal gastrinomas.
Gastroenterology 2005;128(5):1187-98.
2005: Martin Anlauf; Daniel Wieben; Aurel Perren; Bence Sipos; Paul Komminoth; Andreas Raffel; Marie-Luise Kruse; Christian Fottner; Wolfram T Knoefel; Heiner Mönig; Philipp U Heitz; Günter Klöppel
Persistent hyperinsulinemic hypoglycemia in 15 adults with diffuse nesidioblastosis: diagnostic criteria, incidence, and characterization of beta-cell changes.
The American journal of surgical pathology 2005;29(4):524-33.
2005: Hilde Dannenberg; Francien H van Nederveen; Mustaffa Abbou; Albert A J Verhofstad; Paul Komminoth; Ronald R de Krijger; Winand N M Dinjens
Clinical characteristics of pheochromocytoma patients with germline mutations in SDHD.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2005;23(9):1894-901.
2004: Aurel Perren; Sonja Schmid; Tamara Locher; Parvin Saremaslani; C Bonvin; Philipp U Heitz; Paul Komminoth
BRAF and endocrine tumors: mutations are frequent in papillary thyroid carcinomas, rare in endocrine tumors of the gastrointestinal tract and not detected in other endocrine tumors.
Endocrine-related cancer 2004;11(4):855-60.
2004: Daniela Mihic-Probst; Aurel Perren; Sonja Schmid; Parvin Saremaslani; Paul Komminoth; Philipp U Heitz
Absence of BRAF gene mutations differentiates spitz nevi from malignant melanoma.
Anticancer research 2004;24(4):2415-8.
2004: Aurel Perren; Paul Komminoth; Philipp U Heitz
Molecular genetics of gastroenteropancreatic endocrine tumors.
Annals of the New York Academy of Sciences 2004;1014():199-208.
2004: Daniela Mihic-Probst; Jianming Zhao; Parvin Saremaslani; Angela Baer; Christian Oehlschlegel; Bruno Paredes; Paul Komminoth; Philipp U Heitz
CGH analysis shows genetic similarities and differences in atypical fibroxanthoma and undifferentiated high grade pleomorphic sarcoma.
Anticancer research 2004;24(1):19-26.
2004: Margarete Maier-Woelfle; Michael Brändle; Paul Komminoth; Parvin Saremaslani; Sonja Schmid; Tamara Locher; Philipp U Heitz; Ina Krull; Renato L Galeazzi; Christoph Schmid; Aurel Perren
A novel succinate dehydrogenase subunit B gene mutation, H132P, causes familial malignant sympathetic extraadrenal paragangliomas.
The Journal of clinical endocrinology and metabolism 2004;89(1):362-7.
2003: Aurel Perren; Parvin Saremaslani; Sonja Schmid; Claudia Bonvin; Tamara Locher; Juergen Roth; Philipp U Heitz; Paul Komminoth
DPC4/Smad4: no mutations, rare allelic imbalances, and retained protein expression in pancreatic endocrine tumors.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2003;12(4):181-6.
2003: Daniela Mihic-Probst; Parvin Saremaslani; Paul Komminoth; Philipp U Heitz
Immunostaining for the tumour suppressor gene p16 product is a useful marker to differentiate melanoma metastasis from lymph-node nevus.
Virchows Archiv : an international journal of pathology 2003;443(6):745-51.
2003: Hilde Dannenberg; Ronald R de Krijger; Erwin van der Harst; Mustaffa Abbou; Ynske IJzendoorn; Paul Komminoth; Winand N M Dinjens
Von Hippel-Lindau gene alterations in sporadic benign and malignant pheochromocytomas.
International journal of cancer. Journal international du cancer 2003;105(2):190-5.
2003: Romeo Ricci; Paul Komminoth; Fridolin Bannwart; Joachim Torhorst; Edward Wight; Philipp U Heitz; Rosmarie F Caduff
PTEN as a molecular marker to distinguish metastatic from primary synchronous endometrioid carcinomas of the ovary and uterus.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2003;12(2):71-8.
2003: Gabor Szinnai; Christian Meier; Paul Komminoth; Urs W Zumsteg
Review of multiple endocrine neoplasia type 2A in children: therapeutic results of early thyroidectomy and prognostic value of codon analysis.
Pediatrics 2003;111(2):E132-9.
2003: Hilde Dannenberg; Paul Komminoth; Winand N M Dinjens; Ernst J M Speel; Ronald R de Krijger
Molecular genetic alterations in adrenal and extra-adrenal pheochromocytomas and paragangliomas.
Endocrine pathology 2003;14(4):329-50.
2002: Aurel Perren; Andre Barghorn; Sonja Schmid; Parvin Saremaslani; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Absence of somatic SDHD mutations in sporadic neuroendocrine tumors and detection of two germline variants in paraganglioma patients.
Oncogene 2002;21(49):7605-8.
2002: Jianming Zhao; Jürgen Roth; Beata Bode-Lesniewska; Madeleine Pfaltz; Philipp U Heitz; Paul Komminoth
Combined comparative genomic hybridization and genomic microarray for detection of gene amplifications in pulmonary artery intimal sarcomas and adrenocortical tumors.
Genes, chromosomes & cancer 2002;34(1):48-57.
2002: Ingrid Stallmach; Petra Zenklusen; Paul Komminoth; Stephan Schmid; Aurel Perren; Malgorzata Roos; Zhao Jianming; Philipp U Heitz; Madeleine Pfaltz
Loss of heterozygosity at chromosome 6q23-25 correlates with clinical and histologic parameters in salivary gland adenoid cystic carcinoma.
Virchows Archiv : an international journal of pathology 2002;440(1):77-84.
2001: Daniela Mihic-Probst; Jianming Zhao; Parvin Saremaslani; A Baer; Paul Komminoth; Philipp U Heitz
Spitzoid malignant melanoma with lymph-node metastasis. Is a copy-number loss on chromosome 6q a marker of malignancy?
Virchows Archiv : an international journal of pathology 2001;439(6):823-6.
2001: Jianming Zhao; Holger Moch; Alexander Scheidweiler; A Baer; A A Schäffer; Ernst J M Speel; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genomic imbalances in the progression of endocrine pancreatic tumors.
Genes, chromosomes & cancer 2001;32(4):364-72.
2001: Andre Barghorn; Paul Komminoth; D Bachmann; K Rütimann; Parvin Saremaslani; S Muletta-Feurer; Aurel Perren; Jürgen Roth; Philipp U Heitz; Ernst J M Speel
Deletion at 3p25.3-p23 is frequently encountered in endocrine pancreatic tumours and is associated with metastatic progression.
The Journal of pathology 2001;194(4):451-8.
2001: Ernst J M Speel; Alexander Scheidweiler; Jianming Zhao; Christian M Matter; Parvin Saremaslani; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genetic evidence for early divergence of small functioning and nonfunctioning endocrine pancreatic tumors: gain of 9Q34 is an early event in insulinomas.
Cancer research 2001;61(13):5186-92.
2001: Hilde Dannenberg; Ronald R de Krijger; J Zhao; Ernst J M Speel; Parvin Saremaslani; Winand N M Dinjens; Wolter J Mooi; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Differential loss of chromosome 11q in familial and sporadic parasympathetic paragangliomas detected by comparative genomic hybridization.
The American journal of pathology 2001;158(6):1937-42.
2001: Andre Barghorn; Ernst J M Speel; B Farspour; Parvin Saremaslani; Sonja Schmid; Aurel Perren; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Putative tumor suppressor loci at 6q22 and 6q23-q24 are involved in the malignant progression of sporadic endocrine pancreatic tumors.
The American journal of pathology 2001;158(6):1903-11.
2001: Beata Bode-Lesniewska; Jianming Zhao; E J Speel; A M Biraima; M Turina; Paul Komminoth; Philipp U Heitz
Gains of 12q13-14 and overexpression of mdm2 are frequent findings in intimal sarcomas of the pulmonary artery.
Virchows Archiv : an international journal of pathology 2001;438(1):57-65.
2000: Jianming Zhao; Ronald R de Krijger; D Meier; Ernst J M Speel; Parvin Saremaslani; S Muletta-Feurer; Christian M Matter; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genomic alterations in well-differentiated gastrointestinal and bronchial neuroendocrine tumors (carcinoids): marked differences indicating diversity in molecular pathogenesis.
The American journal of pathology 2000;157(5):1431-8.
2000: Aurel Perren; Paul Komminoth; Parvin Saremaslani; Christian M Matter; S Feurer; J A Lees; Philipp U Heitz; C Eng
Mutation and expression analyses reveal differential subcellular compartmentalization of PTEN in endocrine pancreatic tumors compared to normal islet cells.
The American journal of pathology 2000;157(4):1097-103.
2000: K Allenspach; P Arnold; Tony M Glaus; Beat Hauser; C Wolff; C Eberle; Paul Komminoth
Glucagon-producing neuroendocrine tumour associated with hypoaminoacidaemia and skin lesions.
The Journal of small animal practice 2000;41(9):402-6.
2000: Hilde Dannenberg; Ernst J M Speel; J Zhao; Parvin Saremaslani; Erwin van der Harst; Jürgen Roth; Philipp U Heitz; H Jaap Bonjer; Winand N M Dinjens; Wolter J Mooi; Paul Komminoth; Ronald R de Krijger
Losses of chromosomes 1p and 3q are early genetic events in the development of sporadic pheochromocytomas.
The American journal of pathology 2000;157(2):353-9.
2000: Ronald R de Krijger; Erwin van der Harst; S Muletta-Feurer; Hajo A Bruining; Steven W J Lamberts; Winand N M Dinjens; Jürgen Roth; Philipp U Heitz; Paul Komminoth
RET is expressed but not mutated in extra-adrenal paragangliomas.
The Journal of pathology 2000;191(3):264-8.
2000: Ernst J M Speel; Anton H N Hopman; Paul Komminoth
Signal amplification for DNA and mRNA.
Methods in molecular biology (Clifton, N.J.) 2000;123():195-216.
1999: Paul Komminoth; Christian Zuber
Histochemistry and cell biology: what's in a name?
Histochemistry and cell biology 1999;112(6):405-15.
1999: Ernst J M Speel; J Richter; Holger Moch; C Egenter; Parvin Saremaslani; K Rütimann; Jianming Zhao; Andre Barghorn; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Genetic differences in endocrine pancreatic tumor subtypes detected by comparative genomic hybridization.
The American journal of pathology 1999;155(6):1787-94.
1999: Jianming Zhao; Ernst J M Speel; S Muletta-Feurer; K Rütimann; Parvin Saremaslani; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Analysis of genomic alterations in sporadic adrenocortical lesions. Gain of chromosome 17 is an early event in adrenocortical tumorigenesis.
The American journal of pathology 1999;155(4):1039-45.
1999: Paul Komminoth
Review: multiple endocrine neoplasia type 1, sporadic neuroendocrine tumors, and MENIN.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1999;8(3):107-12.
1999: Ernst J M Speel; Anton H N Hopman; Paul Komminoth
Amplification methods to increase the sensitivity of in situ hybridization: play card(s).
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 1999;47(3):281-8.
1999: B Görtz; Jürgen Roth; A Krähenmann; Ronald R de Krijger; S Muletta-Feurer; K Rütimann; Parvin Saremaslani; Ernst J M Speel; Philipp U Heitz; Paul Komminoth
Mutations and allelic deletions of the MEN1 gene are associated with a subset of sporadic endocrine pancreatic and neuroendocrine tumors and not restricted to foregut neoplasms.
The American journal of pathology 1999;154(2):429-36.
1999: B Görtz; Jürgen Roth; Ernst J M Speel; A Krähenmann; Ronald R de Krijger; X Matias-Guiu; S Muletta-Feurer; K Rütmann; Parvin Saremaslani; Philipp U Heitz; Paul Komminoth
MEN1 gene mutation analysis of sporadic adrenocortical lesions.
International journal of cancer. Journal international du cancer 1999;80(3):373-9.
1998: Aurel Perren; Jürgen Roth; S Muletta-Feurer; Parvin Saremaslani; Ernst J M Speel; Philipp U Heitz; Paul Komminoth
Clonal analysis of sporadic pancreatic endocrine tumours.
The Journal of pathology 1998;186(4):363-71.
1998: Ernst J M Speel; Parvin Saremaslani; Jürgen Roth; Anton H N Hopman; Paul Komminoth
Improved mRNA in situ hybridization on formaldehyde-fixed and paraffin-embedded tissue using signal amplification with different haptenized tyramides.
Histochemistry and cell biology 1998;110(6):571-7.
1998: Erwin van der Harst; Ronald R de Krijger; Hajo A Bruining; S W Lamberts; H Jaap Bonjer; W N Dinjes; C Proye; Jan W Koper; Fred T Bosman; J Roth; Philipp U Heitz; Paul Komminoth
Prognostic value of RET proto-oncogene point mutations in malignant and benign, sporadic phaeochromocytomas.
International journal of cancer. Journal international du cancer 1998;79(5):537-40.
1998: Seife Hailemariam; Ariana Gaspert; Paul Komminoth; Pheroze Tamboli; Mahul B Amin
Primary, pure, large-cell neuroendocrine carcinoma of the urinary bladder.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 1998;11(10):1016-20.
1998: Paul Komminoth; Philipp U Heitz; G Klöppel
Pathology of MEN-1: morphology, clinicopathologic correlations and tumour development.
Journal of internal medicine 1998;243(6):455-64.
1997: Paul Komminoth; M Werner
Target and signal amplification: approaches to increase the sensitivity of in situ hybridization.
Histochemistry and cell biology 1997;108(4-5):325-33.
1997: Paul Komminoth
The RET proto-oncogene in medullary and papillary thyroid carcinoma. Molecular features, pathophysiology and clinical implications.
Virchows Archiv : an international journal of pathology 1997;431(1):1-9.
1997: Paul Komminoth
Multiple endocrine neoplasia type 1 and 2: from morphology to molecular pathology 1997.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1997;81():125-38.
1997: S Schröder; B Padberg; M Reincke; Paul Komminoth
[Diagnostic guidelines for adrenal gland nodules: typing, assessment of biological potential and prognosis, molecular pathogenesis].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1997;81():97-102.
1996: Paul Komminoth; W K Seelentag; Parvin Saremaslani; Philipp U Heitz; Jürgen Roth
CD44 isoform expression in the diffuse neuroendocrine system. II. Benign and malignant tumors.
Histochemistry and cell biology 1996;106(6):551-62.
1996: W K Seelentag; Paul Komminoth; Parvin Saremaslani; Philipp U Heitz; Jürgen Roth
CD44 isoform expression in the diffuse neuroendocrine system. I. Normal cells and hyperplasia.
Histochemistry and cell biology 1996;106(6):543-50.
1996: W P Li; Paul Komminoth; Christian Zuber; G Klöppel; Philipp U Heitz; Jürgen Roth
Can malignancy in insulinoma be predicted by the expression patterns of beta 1,6 branching of asparagine-linked oligosaccharides and polysialic acid of the neural cell adhesion molecule?
Virchows Archiv : an international journal of pathology 1996;429(4-5):197-204.
1996: Olaf Hiort; S P Naber; A Lehners; S Muletta-Feurer; G H G Sinnecker; A Zöllner; Paul Komminoth
The role of androgen receptor gene mutations in male breast carcinoma.
The Journal of clinical endocrinology and metabolism 1996;81(9):3404-7.
1996: Paul Komminoth; S Muletta-Feurer; A Soltermann; E Gemsenjäger; H Bürgi; J J Staub; E Schönle; M Fried; W Vetter; G A Spinas; Philipp U Heitz
[Detection of RET-proto-oncogene mutations in the diagnosis of Type 2 endocrine neoplasia (MEN 2)].
Schweizerische medizinische Wochenschrift 1996;126(31-32):1329-38.
1996: Jürgen Roth; Christian Zuber; Paul Komminoth; T Sata; W P Li; Philipp U Heitz
Applications of immunogold and lectin-gold labeling in tumor research and diagnosis.
Histochemistry and cell biology 1996;106(1):131-48.
1996: Paul Komminoth; Jürgen Roth; S Muletta-Feurer; Parvin Saremaslani; W K Seelentag; Philipp U Heitz
RET proto-oncogene point mutations in sporadic neuroendocrine tumors.
The Journal of clinical endocrinology and metabolism 1996;81(6):2041-6.
1995: B C Padberg; S Schröder; W Jochum; Hartwig Kastendieck; Jürgen Roth; Philipp U Heitz; Paul Komminoth
Absence of RET proto-oncogene point mutations in sporadic hyperplastic and neoplastic lesions of the parathyroid gland.
The American journal of pathology 1995;147(6):1600-7.
1995: S Schröder; Paul Komminoth; B Padberg; Philipp U Heitz
[Morphological typing, evaluation of tumor dignity and prognosis and etiologic classification of adrenomedullary and adrenocortical neoplasias].
Der Pathologe 1995;16(5):307-14.
1995: Paul Komminoth; E K Kunz; Xavier Matias-Guiu; Olaf Hiort; G Christiansen; A Colomer; Jürgen Roth; Philipp U Heitz
Analysis of RET protooncogene point mutations distinguishes heritable from nonheritable medullary thyroid carcinomas.
Cancer 1995;76(3):479-89.
1995: Jürgen Roth; Paul Komminoth; Philipp U Heitz
Topographic abnormalities of proinsulin to insulin conversion in functioning human insulinomas. Comparison of immunoelectron microscopic and clinical data.
The American journal of pathology 1995;147(2):489-502.
1995: Xavier Matias-Guiu; A Colomer; E Mato; M Cuatrecasas; Paul Komminoth; Jaime Prat; H Wolfe
Expression of the ret proto-oncogene in phaeochromocytoma. An in situ hybridization and northern blot study.
The Journal of pathology 1995;176(1):63-8.
1995: Paul Komminoth; Jürgen Roth; S Schröder; Parvin Saremaslani; Philipp U Heitz
Overlapping expression of immunohistochemical markers and synaptophysin mRNA in pheochromocytomas and adrenocortical carcinomas. Implications for the differential diagnosis of adrenal gland tumors.
Laboratory investigation; a journal of technical methods and pathology 1995;72(4):424-31.
1995: W K Seelentag; Renata Flury; M Schmid; Paul Komminoth; Parvin Saremaslani; U Günthert; Philipp U Heitz; Jürgen Roth
[Expression of CD44 isoforms in normal human liver and also in regenerative and neoplastic liver changes].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1995;79():144-7.
1995: Paul Komminoth
Rudolf-Virchow-Preis 1995. The role of RET proto-oncogene mutation analysis in the diagnosis of multiple endocrine neoplasia type 2 (MEN 2) gene carriers and in the discrimination of sporadic and familial medullary thyroid carcinomas and pheochromocytomas.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1995;79():L-LV.
1994: Paul Komminoth; Volker Adams; A A Long; Jürgen Roth; Parvin Saremaslani; Renata Flury; M Schmid; Philipp U Heitz
Evaluation of methods for hepatitis C virus detection in archival liver biopsies. Comparison of histology, immunohistochemistry, in-situ hybridization, reverse transcriptase polymerase chain reaction (RT-PCR) and in-situ RT-PCR.
Pathology, research and practice 1994;190(11):1017-25.
1994: Paul Komminoth; E Kunz; Olaf Hiort; S Schröder; Xavier Matias-Guiu; G Christiansen; Jürgen Roth; Philipp U Heitz
Detection of RET proto-oncogene point mutations in paraffin-embedded pheochromocytoma specimens by nonradioactive single-strand conformation polymorphism analysis and direct sequencing.
The American journal of pathology 1994;145(4):922-9.
1994: Paul Komminoth; A A Long
Questioning in situ PCR. Detection of epidermal growth factor receptor mRNA in tissue sections from biopsy specimens using in situ polymerase chain reaction.
The American journal of pathology 1994;145(3):742-4.
1994: Paul Komminoth; Jürgen Roth; Parvin Saremaslani; Xavier Matias-Guiu; H J Wolfe; Philipp U Heitz
Polysialic acid of the neural cell adhesion molecule in the human thyroid: a marker for medullary thyroid carcinoma and primary C-cell hyperplasia. An immunohistochemical study on 79 thyroid lesions.
The American journal of surgical pathology 1994;18(4):399-411.
1994: Paul Komminoth; Volker Adams; A A Long; Jürgen Roth; Parvin Saremaslani; Renata Flury; M Schmid; Philipp U Heitz
[Comparison of histology, immunohistochemistry, RT-PCR, in situ hybridization, and in situ RT-PCR for demonstration of hepatitis C virus in paraffin-embedded liver biopsies].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():220-5.
1994: Paul Komminoth; Philipp U Heitz; A A Long
In situ polymerase chain reaction: general methodology and recent advances.
Verhandlungen der Deutschen Gesellschaft für Pathologie 1994;78():146-52.
1993: A A Long; Paul Komminoth; E Lee; H J Wolfe
Comparison of indirect and direct in-situ polymerase chain reaction in cell preparations and tissue sections. Detection of viral DNA, gene rearrangements and chromosomal translocations.
Histochemistry 1993;99(2):151-62.
1993: Paul Komminoth; A A Long
In-situ polymerase chain reaction. An overview of methods, applications and limitations of a new molecular technique.
Virchows Archiv. B, Cell pathology including molecular pathology 1993;64(2):67-73.
1992: Paul Komminoth; A A Long; R Ray; H J Wolfe
In situ polymerase chain reaction detection of viral DNA, single-copy genes, and gene rearrangements in cell suspensions and cytospins.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 1992;1(2):85-97.
1991: Paul Komminoth; Jürgen Roth; P M Lackie; D Bitter-Suermann; Philipp U Heitz
Polysialic acid of the neural cell adhesion molecule distinguishes small cell lung carcinoma from carcinoids.
The American journal of pathology 1991;139(2):297-304.
1990: Philipp U Heitz; Paul Komminoth; P M Lackie; Christian Zuber; Jürgen Roth
[Demonstration of polysialic acid and N-CAM in neuroendocrine tumors].
Verhandlungen der Deutschen Gesellschaft für Pathologie 1990;74():376-7.
1989: Paul Komminoth; J W Grant; Philipp U Heitz
[A high- resolution video-graphic printer for the documentation of surgical specimens].
Der Pathologe 1989;10(2):131-2.