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Hannu Komulainen

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Päivi Heikkinen; Heinrich Ernst; Hannele Huuskonen; Hannu Komulainen; Timo Heikki Kumlin; Jorma Mäki-Paakkanen; Lauri Puranen; Jukka Juutilainen
No effects of radiofrequency radiation on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-induced tumorigenesis in female Wistar rats.
Päivi Kurttio; Aimo Harmoinen; Heikki Saha; Laina Salonen; Zeev Karpas; Hannu Komulainen; Anssi Auvinen
Kidney toxicity of ingested uranium from drinking water.
Pasi Hakulinen; Elina Rintala; Jorma Mäki-Paakkanen; Hannu Komulainen
Altered expression of connexin43 in the inhibition of gap junctional intercellular communication by chlorohydroxyfuranones in WB-F344 rat liver epithelial cells.

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2006: Päivi Heikkinen; Heinrich Ernst; Hannele Huuskonen; Hannu Komulainen; Timo Heikki Kumlin; Jorma Mäki-Paakkanen; Lauri Puranen; Jukka Juutilainen
No effects of radiofrequency radiation on 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone-induced tumorigenesis in female Wistar rats.
Radiation research 2006;166(2):397-408.
2006: Päivi Kurttio; Aimo Harmoinen; Heikki Saha; Laina Salonen; Zeev Karpas; Hannu Komulainen; Anssi Auvinen
Kidney toxicity of ingested uranium from drinking water.
American journal of kidney diseases : the official journal of the National Kidney Foundation 2006;47(6):972-82.
2006: Pasi Hakulinen; Elina Rintala; Jorma Mäki-Paakkanen; Hannu Komulainen
Altered expression of connexin43 in the inhibition of gap junctional intercellular communication by chlorohydroxyfuranones in WB-F344 rat liver epithelial cells.
Toxicology and applied pharmacology 2006;212(2):146-55.
2005: Zeev Karpas; O Paz-Tal; Avi Lorber; Laina Salonen; Hannu Komulainen; Anssi Auvinen; Heikki Saha; Päivi Kurttio
Urine, hair, and nails as indicators for ingestion of uranium in drinking water.
Health physics 2005;88(3):229-42.
2005: Päivi Kurttio; Hannu Komulainen; Aila Leino; Laina Salonen; Anssi Auvinen; Heikki Saha
Bone as a possible target of chemical toxicity of natural uranium in drinking water.
Environmental health perspectives 2005;113(1):68-72.
2004: Pasi Hakulinen; Jorma Mäki-Paakkanen; Jonne Naarala; Leif Kronberg; Hannu Komulainen
Potent inhibition of gap junctional intercellular communication by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in BALB/c 3T3 cells.
Toxicology letters 2004;151(3):439-49.
2004: Hannu Komulainen
Experimental cancer studies of chlorinated by-products.
Toxicology 2004;198(1-3):239-48.
2004: Mikko Holopainen; Maija-Riitta Hirvonen; Hannu Komulainen; Matti Klockars
Effect of the shape of mica particles on the production of tumor necrosis factor alpha in mouse macrophages.
Scandinavian journal of work, environment & health 2004;30 Suppl 2():91-8.
2004: Jorma Mäki-Paakkanen; Hannu Komulainen; Leif Kronberg
Bacterial and mammalian-cell genotoxicity of mixtures of chlorohydroxyfuranones, by-products of water chlorination.
Environmental and molecular mutagenesis 2004;43(4):217-25.
2003: Mariitta Laaksonen; Jorma Mäki-Paakkanen; Leif Kronberg; Hannu Komulainen
Effects of chlorohydroxyfuranones on 3-methylcholanthrene-induced neoplastic transformation in the two-stage transformation assay in C3H 10T1/2 cells.
Archives of toxicology 2003;77(10):594-600.
2003: Hannu Komulainen
On-line information sources of toxicology in Finland.
Toxicology 2003;190(1-2):15-21.
2003: Hannele Huuskonen; Raili Venäläinen; Hannu Komulainen
Developmental toxicity evaluation of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in Wistar rats.
Birth defects research. Part B, Developmental and reproductive toxicology 2003;68(2):172-9.
2003: Päivi Heikkinen; Veli-Matti Kosma; Leena Alhonen; Hannele Huuskonen; Hannu Komulainen; Timo Heikki Kumlin; Jarmo T Laitinen; S Lang; Lauri Puranen; Jukka Juutilainen
Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.
International journal of radiation biology 2003;79(4):221-33.
2003: Juha Jussila; Jukka Pelkonen; Veli-Matti Kosma; Jorma Mäki-Paakkanen; Hannu Komulainen; Maija-Riitta Hirvonen
Systemic immunoresponses in mice after repeated exposure of lungs to spores of Streptomyces californicus.
Clinical and diagnostic laboratory immunology 2003;10(1):30-7.
2003: Kati Huttunen; Aapo Hyvärinen; Aino Nevalainen; Hannu Komulainen; Maija-Riitta Hirvonen
Production of proinflammatory mediators by indoor air bacteria and fungal spores in mouse and human cell lines.
Environmental health perspectives 2003;111(1):85-92.
2002: Juha Jussila; Hannu Komulainen; Veli-Matti Kosma; Aino Nevalainen; Jukka Pelkonen; Maija-Riitta Hirvonen
Spores of Aspergillus versicolor isolated from indoor air of a moisture-damaged building provoke acute inflammation in mouse lungs.
Inhalation toxicology 2002;14(12):1261-77.
2002: Juha Jussila; Hannu Komulainen; Kati Huttunen; Marjut Roponen; Eila Iivanainen; Pirjo Torkko; Veli-Matti Kosma; Jukka Pelkonen; Maija-Riitta Hirvonen
Mycobacterium terrae isolated from indoor air of a moisture-damaged building induces sustained biphasic inflammatory response in mouse lungs.
Environmental health perspectives 2002;110(11):1119-25.
2002: Juha Jussila; Hannu Komulainen; Veli-Matti Kosma; Jukka Pelkonen; Maija-Riitta Hirvonen
Inflammatory potential of the spores of Penicillium spinulosum isolated from indoor air of a moisture-damaged building in mouse lungs.
Environmental toxicology and pharmacology 2002;12(3):137-45.
2002: Päivi Kurttio; Anssi Auvinen; Laina Salonen; Heikki Saha; Juha Pekkanen; Ilona Mäkeläinen; Sami Väisänen; Ilkka M Penttilä; Hannu Komulainen
Renal effects of uranium in drinking water.
Environmental health perspectives 2002;110(4):337-42.
2002: Pasi Hakulinen; Veli-Matti Kosma; Hannu Komulainen
Expression of p53 and p21 Ki-ras proteins in rat thyroid gland tumors induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).
Anticancer research 2002;22(2A):703-6.
2001: Mariitta Laaksonen; Jorma Mäki-Paakkanen; Hannu Komulainen
Enhancement of 3-methylcholanthrene-induced neoplastic transformation by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone in the two-stage transformation assay in C3H 10T1/2 cells.
Archives of toxicology 2001;75(10):613-7.
2001: Päivi Heikkinen; Veli-Matti Kosma; T Hongisto; Hannele Huuskonen; P Hyysalo; Hannu Komulainen; Timo Heikki Kumlin; Tapani Lahtinen; S Lang; Lauri Puranen; Jukka Juutilainen
Effects of mobile phone radiation on X-ray-induced tumorigenesis in mice.
Radiation research 2001;156(6):775-85.
2001: Marjut Roponen; Mika Toivola; Teija Meklin; M Ruotsalainen; Hannu Komulainen; Aino Nevalainen; Maija-Riitta Hirvonen
Differences in inflammatory responses and cytotoxicity in RAW264.7 macrophages induced by Streptomyces Anulatus grown on different building materials.
Indoor air 2001;11(3):179-84.
2001: Hannele Huuskonen; Jukka Juutilainen; Hannu Komulainen
Development of preimplantation mouse embryos after exposure to a 50 Hz magnetic field in vitro.
Toxicology letters 2001;122(2):149-55.
2001: Päivi Heikkinen; Veli-Matti Kosma; Hannele Huuskonen; Hannu Komulainen; Timo Heikki Kumlin; Ilkka M Penttilä; A Väänänen; Jukka Juutilainen
Effects of 50 Hz magnetic fields on cancer induced by ionizing radiation in mice.
International journal of radiation biology 2001;77(4):483-95.
2001: Timo Murtoniemi; Aino Nevalainen; Merja Suutari; Mika Toivola; Hannu Komulainen; Maija-Riitta Hirvonen
Induction of cytotoxicity and production of inflammatory mediators in raw264.7 macrophages by spores grown on six different plasterboards.
Inhalation toxicology 2001;13(3):233-47.
2001: Juha Jussila; Hannu Komulainen; Kati Huttunen; Marjut Roponen; Arja I Hälinen; Aapo Hyvärinen; Veli-Matti Kosma; Jukka Pelkonen; Maija-Riitta Hirvonen
Inflammatory responses in mice after intratracheal instillation of spores of Streptomyces californicus isolated from indoor air of a moldy building.
Toxicology and applied pharmacology 2001;171(1):61-9.
2001: Jorma Mäki-Paakkanen; Mariitta Laaksonen; Tony Munter; Leif Kronberg; Hannu Komulainen
Comparable DNA and chromosome damage in Chinese hamster ovary cells by chlorohydroxyfuranones.
Environmental and molecular mutagenesis 2001;38(4):297-305.
2001: Hannele Huuskonen; V Saastamoinen; Hannu Komulainen; J Laitinen; Jukka Juutilainen
Effects of low-frequency magnetic fields on implantation in rats.
Reproductive toxicology (Elmsford, N.Y.) 2001;15(1):49-59.
2000: Hannu Komulainen; Pasi Hakulinen; Kristina Servomaa; Kaisa Makkonen; R Vasara; Jorma Mäki-Paakkanen; Veli-Matti Kosma
No consistent pattern of mutations in p53 and ras genes in liver tumors of rat treated with the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).
Environmental and molecular mutagenesis 2000;36(4):292-300.
1999: Maija-Riitta Hirvonen; M Ruotsalainen; Marjut Roponen; Aapo Hyvärinen; Tuula Husman; Veli-Matti Kosma; Hannu Komulainen; Kai Savolainen; Aino Nevalainen
Nitric oxide and proinflammatory cytokines in nasal lavage fluid associated with symptoms and exposure to moldy building microbes.
American journal of respiratory and critical care medicine 1999;160(6):1943-6.
1999: Juha Jussila; Hannu Komulainen; Aino Nevalainen; Mirja Ruotsalainen; Kai Savolainen; Maija-Riitta Hirvonen
Streptomyces anulatus from indoor air of moldy houses induce NO and IL-6 production in a human alveolar epithelial cell-line.
Environmental toxicology and pharmacology 1999;7(4):261-6.
1999: A J Hälinen; Hannu Komulainen; Mirja Ruotsalainen; R O Salonen; Maija-Riitta Hirvonen
Diesel particles induce nitric oxide production in murine alveolar macrophages and rat airways.
Environmental toxicology and pharmacology 1999;7(1):11-8.
1998: Hannele Huuskonen; Jukka Juutilainen; Antero Julkunen; Jorma Mäki-Paakkanen; Hannu Komulainen
Effects of gestational exposure to a video display terminal-like magnetic field (20-kHz) on CBA/S mice.
Teratology 1998;58(5):190-6.
1998: Päivi Kurttio; Hannu Komulainen; E Hakala; H Kahelin; Juha Pekkanen
Urinary excretion of arsenic species after exposure to arsenic present in drinking water.
Archives of environmental contamination and toxicology 1998;34(3):297-305.
1998: Hannele Huuskonen; Jukka Juutilainen; Antero Julkunen; Jorma Mäki-Paakkanen; Hannu Komulainen
Effects of low-frequency magnetic fields on fetal development in CBA/Ca mice.
Bioelectromagnetics 1998;19(8):477-85.
1998: Timo Heikki Kumlin; Veli-Matti Kosma; Leena Alhonen; Juhani Jänne; Hannu Komulainen; S Lang; Tapio Rytömaa; Kristina Servomaa; Jukka Juutilainen
Effects of 50 Hz magnetic fields on UV-induced skin tumourigenesis in ODC-transgenic and non-transgenic mice.
International journal of radiation biology 1998;73(1):113-21.
1997: Hannu Komulainen; Veli-Matti Kosma; S L Vaittinen; Terttu Vartiainen; E Kaliste-Korhonen; S Lötjönen; R K Tuominen; Jouko Tuomisto
Carcinogenicity of the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone in the rat.
Journal of the National Cancer Institute 1997;89(12):848-56.
1997: Jukka Juutilainen; Hannele Huuskonen; Hannu Komulainen
Increased resorptions in CBA mice exposed to low-frequency magnetic fields: an attempt to replicate earlier observations.
Bioelectromagnetics 1997;18(6):410-7.
1996: Sirpa Pennanen; A Kojo; M Pasanen; Jyrki Liesivuori; Risto O Juvonen; Hannu Komulainen
CYP enzymes catalyze the formation of a terminal olefin from 2-ethylhexanoic acid in rat and human liver.
Human & experimental toxicology 1996;15(5):435-42.
1995: S L Vaittinen; Hannu Komulainen; V M Kosma; Antero Julkunen; Jorma Mäki-Paakkanen; K Jansson; Terttu Vartiainen; J Tuomisto
Subchronic toxicity of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in Wistar rats.
Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association 1995;33(12):1027-37.
1995: Hannu Komulainen; A Keränen; Veijo Saano
Triethyllead decreases central benzodiazepine receptor binding in rat cerebellum ex vivo.
European journal of pharmacology 1995;293(2):167-71.
1995: KM Heiskanen; P Linström-Seppä; L Haataja; S L Vaittinen; Terttu Vartiainen; Hannu Komulainen
Altered enzyme activities of xenobiotic biotransformation in kidneys after subchronic administration of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) to rats.
Toxicology 1995;100(1-3):121-8.
1995: Hannu Komulainen; A Keränen; Veijo Saano
Methylmercury modulates GABAA receptor complex differentially in rat cortical and cerebellar membranes in vitro.
Neurochemical research 1995;20(6):659-62.
1994: Hannu Komulainen; Hannele Huuskonen; V M Kosma; S Lötjönen; Terttu Vartiainen
Toxic effects and excretion in urine of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in the after a single oral dose.
Archives of toxicology 1994;68(6):398-400.
1993: Sirpa Pennanen; K Tuovinen; Hannele Huuskonen; V M Kosma; Hannu Komulainen
Effects of 2-ethylhexanoic acid on reproduction and postnatal development in Wistar rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1993;21(2):204-12.
1993: L Risto; Terttu Vartiainen; Hannu Komulainen
Formation of methemoglobin by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone, MX, in rat erythrocytes in vitro.
Toxicology letters 1993;68(3):325-32.
1993: Maija-Riitta Hirvonen; Hannu Komulainen; Kai Savolainen
Carbachol- and KCl-induced changes in phosphoinositide metabolism and free calcium in guinea pig cerebral cortex synaptosomes.
Neurochemical research 1993;18(5):579-83.
1993: K Jansson; Jorma Mäki-Paakkanen; S L Vaittinen; Terttu Vartiainen; Hannu Komulainen; J Tuomisto
Cytogenetic effects of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX) in rat peripheral lymphocytes in vitro and in vivo.
Mutation research 1993;299(1):25-8.
1993: Hannele Huuskonen; Jukka Juutilainen; Hannu Komulainen
Effects of low-frequency magnetic fields on fetal development in rats.
Bioelectromagnetics 1993;14(3):205-13.
1992: Sirpa Pennanen; K Tuovinen; Hannele Huuskonen; Hannu Komulainen
The developmental toxicity of 2-ethylhexanoic acid in Wistar rats.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1992;19(4):505-11.
1992: Hannu Komulainen; S L Vaittinen; Terttu Vartiainen; S Lötjönen; Timo Petteri Paronen; J Tuomisto
Pharmacokinetics in rat of 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX), a drinking water mutagen, after a single dose.
Pharmacology & toxicology 1992;70(6 Pt 1):424-8.
1991: Sirpa Pennanen; S Auriola; A Manninen; Hannu Komulainen
Identification of the main metabolites of 2-ethylhexanoic acid in rat urine using gas chromatography-mass spectrometry.
Journal of chromatography 1991;568(1):125-34.
1991: O Raatikainen; Risto A Kauppinen; Hannu Komulainen; Hannu Taipale; Tuula Pirttilä; J Tuomisto
Polyene antibiotics increase the ionic permeability of synaptosomal plasma membranes.
Biochemical pharmacology 1991;41(9):1345-50.
1990: Maija-Riitta Hirvonen; Leo Paljärvi; A Naukkarinen; Hannu Komulainen; Kai Savolainen
Potentiation of malaoxon-induced convulsions by lithium: early neuronal injury, phosphoinositide signaling, and calcium.
Toxicology and applied pharmacology 1990;104(2):276-89.
1989: Pekka T Männistö; H Hanhijärvi; A Havas; A Vuorela; Hannu Komulainen; V Rauramaa
Efficacy of erythromycin acistrate (2'-acetyl erythromycin stearate) and erythromycin stearate in experimental infections in mice.
The Journal of pharmacology and experimental therapeutics 1989;250(3):1028-33.
1989: Risto A Kauppinen; Hannu Taipale; Hannu Komulainen
Interrelationships between glucose metabolism, energy state, and the cytosolic free calcium concentration in cortical synaptosomes from the guinea pig.
Journal of neurochemistry 1989;53(3):766-71.
1989: Hannu Taipale; Risto A Kauppinen; Hannu Komulainen
Ruthenium red inhibits the voltage-dependent increase in cytosolic free calcium in cortical synaptosomes from guinea-pig.
Biochemical pharmacology 1989;38(7):1109-13.
1989: Risto A Kauppinen; Hannu Komulainen; Hannu Taipale
Cellular mechanisms underlying the increase in cytosolic free calcium concentration induced by methylmercury in cerebrocortical synaptosomes from guinea pig.
The Journal of pharmacology and experimental therapeutics 1989;248(3):1248-54.
1989: Maija-Riitta Hirvonen; Hannu Komulainen; Leo Paljärvi; Kai Savolainen
Time-course of malaoxon-induced alterations in brain regional inositol-1-phosphate levels in convulsing and nonconvulsing rats.
Neurochemical research 1989;14(2):143-7.
1989: Veijo Saano; O Raatikainen; Timo Petteri Paronen; Hannu Komulainen
Pharmacokinetics and acute side-effects of nifedipine given as slow-release tablets or liquid-filled capsules.
International journal of clinical pharmacology research 1989;9(4):247-54.
1988: Risto A Kauppinen; Hannu Komulainen; Hannu Taipale
Chloride-dependent uncoupling of oxidative phosphorylation by triethyllead and triethyltin increases cytosolic free calcium in guinea pig cerebral cortical synaptosomes.
Journal of neurochemistry 1988;51(5):1617-25.