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Jerry Adams

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Peter Czabotar; Grant Dewson; W Douglas Fairlie; Colin Hockings; David C S Huang; Ruth M Kluck; Erinna Lee; Stephen Ma; Adeline Y Robin; Brian J Smith; Dana Westphal; Shenggen Yao; Jerry M Adams; Peter M Colman
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.
Priscilla N Kelly; Jerry M Adams; A R D Delbridge; S Grabow; Andreas Strasser
Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.
Edwina Naik; Lorraine A O'Reilly; Jerry M Adams; Marie-Liesse Asselin-Labat; Philippe Bouillet; Michele Cook; Leigh Coultas; Ann Lin; Delphine Merino; Andreas Strasser
Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells.

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2013: Peter Czabotar; Grant Dewson; W Douglas Fairlie; Colin Hockings; David C S Huang; Ruth M Kluck; Erinna Lee; Stephen Ma; Adeline Y Robin; Brian J Smith; Dana Westphal; Shenggen Yao; Jerry M Adams; Peter M Colman
Bax crystal structures reveal how BH3 domains activate Bax and nucleate its oligomerization to induce apoptosis.
Cell 2013;152(3):519-31.
2013: Priscilla N Kelly; Jerry M Adams; A R D Delbridge; S Grabow; Andreas Strasser
Prophylactic treatment with the BH3 mimetic ABT-737 impedes Myc-driven lymphomagenesis in mice.
Cell death and differentiation 2013;20(1):57-63.
2011: Edwina Naik; Lorraine A O'Reilly; Jerry M Adams; Marie-Liesse Asselin-Labat; Philippe Bouillet; Michele Cook; Leigh Coultas; Ann Lin; Delphine Merino; Andreas Strasser
Destruction of tumor vasculature and abated tumor growth upon VEGF blockade is driven by proapoptotic protein Bim in endothelial cells.
The Journal of experimental medicine 2011;208(7):1351-8.
2010: Ewa M Michalak; Cassandra J Vandenberg; Alex R D Delbridge; Li Wu; Clare L Scott; Jerry M Adams; Andreas Strasser
Apoptosis-promoted tumorigenesis: gamma-irradiation-induced thymic lymphomagenesis requires Puma-driven leukocyte death.
Genes & development 2010;24(15):1608-13.
2010: Mark F Van Delft; Darrin P Smith; Mireille Lahoud; David C S Huang; Jerry M Adams
Apoptosis and non-inflammatory phagocytosis can be induced by mitochondrial damage without caspases.
Cell death and differentiation 2010;17(5):821-32.
2009: Grant Dewson; Tobias Kratina; Peter Czabotar; Catherine L Day; Jerry M Adams; Ruth M Kluck
Bak activation for apoptosis involves oligomerization of dimers via their alpha6 helices.
Molecular cell 2009;36(4):696-703.
2009: Delphine Mérino; Maybelline Giam; Peter D Hughes; Owen M Siggs; Klaus Heger; Lorraine A O'Reilly; Jerry M Adams; Andreas Strasser; Erinna Lee; W Douglas Fairlie; Philippe Bouillet
The role of BH3-only protein Bim extends beyond inhibiting Bcl-2-like prosurvival proteins.
The Journal of cell biology 2009;186(3):355-62.
2009: Ewa M Michalak; E S Jansen; L Happo; Mark Cragg; L Tai; G K Smyth; Andreas Strasser; Jerry M Adams; C L Scott
Puma and to a lesser extent Noxa are suppressors of Myc-induced lymphomagenesis.
Cell death and differentiation 2009;16(5):684-96.
2008: Jamie I Fletcher; Sarina Meusburger; Christine J Hawkins; David T Riglar; Erinna Lee; W Douglas Fairlie; David C S Huang; Jerry M Adams
Apoptosis is triggered when prosurvival Bcl-2 proteins cannot restrain Bax.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(47):18081-7.
2008: Jerry M Adams; Andreas Strasser
Is tumor growth sustained by rare cancer stem cells or dominant clones?
Cancer research 2008;68(11):4018-21.
2008: Grant Dewson; Tobias Kratina; Huiyan W Sim; Hamsa Puthalakath; Jerry M Adams; Peter M Colman; Ruth M Kluck
To trigger apoptosis, Bak exposes its BH3 domain and homodimerizes via BH3:groove interactions.
Molecular cell 2008;30(3):369-80.
2007: Jerry M Adams; Suzanne Cory
Bcl-2-regulated apoptosis: mechanism and therapeutic potential.
Current opinion in immunology 2007;19(5):488-96.
2007: Priscilla N Kelly; Aleksandar Dakic; Jerry M Adams; Stephen L Nutt; Andreas Strasser
Tumor growth need not be driven by rare cancer stem cells.
Science (New York, N.Y.) 2007;317(5836):337.
2007: Leigh Coultas; Susanna Terzano; Tim Thomas; Anne Voss; Kate Reid; Edouard G Stanley; Clare L Scott; Philippe Bouillet; Perry Bartlett; Jonathan Ham; Jerry M Adams; Andreas Strasser
Hrk/DP5 contributes to the apoptosis of select neuronal populations but is dispensable for haematopoietic cell apoptosis.
Journal of cell science 2007;120(Pt 12):2044-52.
2007: Priscilla N Kelly; Hamsa Puthalakath; Jerry M Adams; Andreas Strasser
Endogenous bcl-2 is not required for the development of Emu-myc-induced B-cell lymphoma.
Blood 2007;109(11):4907-13.
2007: Rachel Uren; Grant Dewson; Lin Chen; Stephanie C Coyne; David C S Huang; Jerry M Adams; Ruth M Kluck
Mitochondrial permeabilization relies on BH3 ligands engaging multiple prosurvival Bcl-2 relatives, not Bak.
The Journal of cell biology 2007;177(2):277-87.
2007: Edwina Naik; Ewa M Michalak; Andreas Villunger; Jerry M Adams; Andreas Strasser
Ultraviolet radiation triggers apoptosis of fibroblasts and skin keratinocytes mainly via the BH3-only protein Noxa.
The Journal of cell biology 2007;176(4):415-24.
2007: Simon N Willis; Jamie I Fletcher; Thomas Kaufmann; Mark F Van Delft; Lin Chen; Peter Czabotar; Helen Ierino; Erinna Lee; W Douglas Fairlie; Philippe Bouillet; Andreas Strasser; Ruth M Kluck; Jerry M Adams; David C S Huang
Apoptosis initiated when BH3 ligands engage multiple Bcl-2 homologs, not Bax or Bak.
Science (New York, N.Y.) 2007;315(5813):856-9.
2006: Mark F Van Delft; Andrew H Wei; Kylie D Mason; Cassandra J Vandenberg; Lin Chen; Peter Czabotar; Simon N Willis; Clare L Scott; Catherine L Day; Suzanne Cory; Jerry M Adams; Andrew W Roberts; David C S Huang
The BH3 mimetic ABT-737 targets selective Bcl-2 proteins and efficiently induces apoptosis via Bak/Bax if Mcl-1 is neutralized.
Cancer cell 2006;10(5):389-99.
2006: Vanessa S Marsden; Thomas Kaufmann; Lorraine A O'Reilly; Jerry M Adams; Andreas Strasser
Apaf-1 and caspase-9 are required for cytokine withdrawal-induced apoptosis of mast cells but dispensable for their functional and clonogenic death.
Blood 2006;107(5):1872-7.
2005: Miriam Erlacher; Ewa M Michalak; Priscilla N Kelly; Verena Labi; Harald Niederegger; Leigh Coultas; Jerry M Adams; Andreas Strasser; Andreas Villunger
BH3-only proteins Puma and Bim are rate-limiting for gamma-radiation- and glucocorticoid-induced apoptosis of lymphoid cells in vivo.
Blood 2005;106(13):4131-8.
2005: Simon N Willis; Jerry M Adams
Life in the balance: how BH3-only proteins induce apoptosis.
Current opinion in cell biology 2005;17(6):617-25.
2005: Leigh Coultas; Philippe Bouillet; Kate L Loveland; Sarah J Meachem; Harris Perlman; Jerry M Adams; Andreas Strasser
Concomitant loss of proapoptotic BH3-only Bcl-2 antagonists Bik and Bim arrests spermatogenesis.
The EMBO journal 2005;24(22):3963-73.
2005: Suzanne Cory; Jerry M Adams
Killing cancer cells by flipping the Bcl-2/Bax switch.
Cancer cell 2005;8(1):5-6.
2005: Simon N Willis; Lin Chen; Grant Dewson; Andrew Wei; Edwina Naik; Jamie I Fletcher; Jerry M Adams; David C S Huang
Proapoptotic Bak is sequestered by Mcl-1 and Bcl-xL, but not Bcl-2, until displaced by BH3-only proteins.
Genes & development 2005;19(11):1294-305.
2005: Lin Chen; Simon N Willis; Andrew Wei; Brian J Smith; Jamie I Fletcher; Mark G Hinds; Peter M Colman; Catherine L Day; Jerry M Adams; David C S Huang
Differential targeting of prosurvival Bcl-2 proteins by their BH3-only ligands allows complementary apoptotic function.
Molecular cell 2005;17(3):393-403.
2005: Jerry M Adams; David C S Huang; Andreas Strasser; S Willis; Lin Chen; Andrew Wei; Mark F Van Delft; Jamie I Fletcher; Hamsa Puthalakath; Junya Kuroda; Ewa M Michalak; Priscilla N Kelly; Philippe Bouillet; Andreas Villunger; Lorraine A O'Reilly; Mary L Bath; Darrin P Smith; Alexander Egle; Alan W Harris; Mark G Hinds; Peter M Colman; Suzanne Cory
Subversion of the Bcl-2 life/death switch in cancer development and therapy.
Cold Spring Harbor symposia on quantitative biology 2005;70():469-77.
2004: Wendy D Cook; Benjamin J McCaw; Christopher Herring; Deborah L John; Simon J Foote; Stephen L Nutt; Jerry M Adams
PU.1 is a suppressor of myeloid leukemia, inactivated in mice by gene deletion and mutation of its DNA binding domain.
Blood 2004;104(12):3437-44.
2004: Vanessa S Marsden; Paul G Ekert; Mark F Van Delft; David L Vaux; Jerry M Adams; Andreas Strasser
Bcl-2-regulated apoptosis and cytochrome c release can occur independently of both caspase-2 and caspase-9.
The Journal of cell biology 2004;165(6):775-80.
2004: Caryn Navarro; Hamsa Puthalakath; Jerry M Adams; Andreas Strasser; Ruth Lehmann
Egalitarian binds dynein light chain to establish oocyte polarity and maintain oocyte fate.
Nature cell biology 2004;6(5):427-35.
2004: Leigh Coultas; Philippe Bouillet; Edouard G Stanley; Thomas C Brodnicki; Jerry M Adams; Andreas Strasser
Proapoptotic BH3-only Bcl-2 family member Bik/Blk/Nbk is expressed in hemopoietic and endothelial cells but is redundant for their programmed death.
Molecular and cellular biology 2004;24(4):1570-81.
2003: Philippe Bouillet; Mikara Robati; Jerry M Adams; Andreas Strasser
Loss of pro-apoptotic BH3-only Bcl-2 family member Bim does not protect mutant Lurcher mice from neurodegeneration.
Journal of neuroscience research 2003;74(5):777-81.
2003: Suzanne Cory; David C S Huang; Jerry M Adams
The Bcl-2 family: roles in cell survival and oncogenesis.
Oncogene 2003;22(53):8590-607.
2003: Andreas Villunger; Ewa M Michalak; Leigh Coultas; Franziska Müllauer; Günther Böck; Michael J Ausserlechner; Jerry M Adams; Andreas Strasser
p53- and drug-induced apoptotic responses mediated by BH3-only proteins puma and noxa.
Science (New York, N.Y.) 2003;302(5647):1036-8.
2003: Jerry M Adams
Ways of dying: multiple pathways to apoptosis.
Genes & development 2003;17(20):2481-95.
2003: Julie Wilson-Annan; Lorraine A O'Reilly; Simon A Crawford; George Hausmann; Jennifer G Beaumont; Loes P Parma; Lin Chen; Martin Lackmann; Trevor Lithgow; Mark G Hinds; Catherine L Day; Jerry M Adams; David C S Huang
Proapoptotic BH3-only proteins trigger membrane integration of prosurvival Bcl-w and neutralize its activity.
The Journal of cell biology 2003;162(5):877-87.
2003: Leigh Coultas; Marc Pellegrini; Jane E Visvader; Geoffrey J Lindeman; Lin Chen; Jerry M Adams; David C S Huang; Andreas Strasser
Bfk: a novel weakly proapoptotic member of the Bcl-2 protein family with a BH3 and a BH2 region.
Cell death and differentiation 2003;10(2):185-92.
2002: Jerry M Adams; Suzanne Cory
Apoptosomes: engines for caspase activation.
Current opinion in cell biology 2002;14(6):715-20.
2002: Leigh Coultas; David C S Huang; Jerry M Adams; Andreas Strasser
Pro-apoptotic BH3-only Bcl-2 family members in vertebrate model organisms suitable for genetic experimentation.
Cell death and differentiation 2002;9(11):1163-6.
2002: Vanessa S Marsden; Liam O'Connor; Lorraine A O'Reilly; John Silke; Donald Metcalf; Paul G Ekert; David C S Huang; Francesco Cecconi; Keisuke Kuida; Kevin J Tomaselli; Sophie Roy; Don W Nicholson; David L Vaux; Philippe Bouillet; Jerry M Adams; Andreas Strasser
Apoptosis initiated by Bcl-2-regulated caspase activation independently of the cytochrome c/Apaf-1/caspase-9 apoptosome.
Nature 2002;419(6907):634-7.
2002: Suzanne Cory; Jerry M Adams
The Bcl2 family: regulators of the cellular life-or-death switch.
Nature reviews. Cancer 2002;2(9):647-56.
2002: Philippe Bouillet; Jared F Purton; Dale I Godfrey; Li-Chen Zhang; Leigh Coultas; Hamsa Puthalakath; Marc Pellegrini; Suzanne Cory; Jerry M Adams; Andreas Strasser
BH3-only Bcl-2 family member Bim is required for apoptosis of autoreactive thymocytes.
Nature 2002;415(6874):922-6.
2001: Philippe Bouillet; Suzanne Cory; Li-Chen Zhang; Andreas Strasser; Jerry M Adams
Degenerative disorders caused by Bcl-2 deficiency prevented by loss of its BH3-only antagonist Bim.
Developmental cell 2001;1(5):645-53.
2001: Philippe Bouillet; Li-Chen Zhang; D C Huang; GC Webb; C D K Bottema; P Shore; H J Eyre; G R Sutherland; Jerry M Adams
Gene structure alternative splicing, and chromosomal localization of pro-apoptotic Bcl-2 relative Bim.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(2):163-8.
2001: Jerry M Adams; Suzanne Cory
Life-or-death decisions by the Bcl-2 protein family.
Trends in biochemical sciences 2001;26(1):61-6.
2000: M Grossmann; Lorraine A O'Reilly; Raffi Gugasyan; Andreas Strasser; Jerry M Adams; Steve Gerondakis
The anti-apoptotic activities of Rel and RelA required during B-cell maturation involve the regulation of Bcl-2 expression.
The EMBO journal 2000;19(23):6351-60.
2000: DM Pritchard; Cristin G Print; Lorraine A O'Reilly; Jerry M Adams; Christopher S Potten; John A Hickman
Bcl-w is an important determinant of damage-induced apoptosis in epithelia of small and large intestine.
Oncogene 2000;19(34):3955-9.
2000: G Vairo; TJ Soos; TM Upton; J Zalvide; James A DeCaprio; Mark E Ewen; Andrew Koff; Jerry M Adams
Bcl-2 retards cell cycle entry through p27(Kip1), pRB relative p130, and altered E2F regulation.
Molecular and cellular biology 2000;20(13):4745-53.
2000: George Hausmann; Lorraine A O'Reilly; R van Driel; Jennifer G Beaumont; Andreas Strasser; Jerry M Adams; David C S Huang
Pro-apoptotic apoptosis protease-activating factor 1 (Apaf-1) has a cytoplasmic localization distinct from Bcl-2 or Bcl-x(L).
The Journal of cell biology 2000;149(3):623-34.
2000: Andreas Strasser; Hamsa Puthalakath; Philippe Bouillet; David C S Huang; L O'Connor; Lorraine A O'Reilly; L Cullen; Suzanne Cory; Jerry M Adams
The role of bim, a proapoptotic BH3-only member of the Bcl-2 family in cell-death control.
Annals of the New York Academy of Sciences 2000;917():541-8.
2000: Philippe Bouillet; David C S Huang; Lorraine A O'Reilly; Hamsa Puthalakath; L O'Connor; Suzanne Cory; Jerry M Adams; Andreas Strasser
The role of the pro-apoptotic Bcl-2 family member bim in physiological cell death.
Annals of the New York Academy of Sciences 2000;926():83-9.
2000: Rivka Ofir; Li-Chen Zhang; A P Kyne; V Houtzager; L O'Connor; Jerry M Adams
Gamma-radiation-induced growth arrest and apoptosis in p53-null lymphoma cells is accompanied by modest transcriptional changes in many genes.
DNA and cell biology 2000;19(1):29-37.
1999: Sarah Ogilvy; Donald Metcalf; Cristin G Print; Mary L Bath; Alan W Harris; Jerry M Adams
Constitutive Bcl-2 expression throughout the hematopoietic compartment affects multiple lineages and enhances progenitor cell survival.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):14943-8.
1999: Rivka Ofir; Li-Chen Zhang; Jerry M Adams
Interference with gene expression induces rapid apoptosis in p53-null T lymphoma cells.
Cell death and differentiation 1999;6(12):1216-21.
1999: Philippe Bouillet; Donald Metcalf; David C S Huang; David M Tarlinton; T W Kay; F Köntgen; Jerry M Adams; Andreas Strasser
Proapoptotic Bcl-2 relative Bim required for certain apoptotic responses, leukocyte homeostasis, and to preclude autoimmunity.
Science (New York, N.Y.) 1999;286(5445):1735-8.
1999: Jerry M Adams; Alan W Harris; Andreas Strasser; Sarah Ogilvy; Suzanne Cory
Transgenic models of lymphoid neoplasia and development of a pan-hematopoietic vector.
Oncogene 1999;18(38):5268-77.
1999: Sarah Ogilvy; Donald Metcalf; L Gibson; Mary L Bath; Alan W Harris; Jerry M Adams
Promoter elements of vav drive transgene expression in vivo throughout the hematopoietic compartment.
Blood 1999;94(6):1855-63.
1999: K Moriishi; David C S Huang; Suzanne Cory; Jerry M Adams
Bcl-2 family members do not inhibit apoptosis by binding the caspase activator Apaf-1.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(17):9683-8.
1999: S P Holmgreen; David C S Huang; Jerry M Adams; Suzanne Cory
Survival activity of Bcl-2 homologs Bcl-w and A1 only partially correlates with their ability to bind pro-apoptotic family members.
Cell death and differentiation 1999;6(6):525-32.
1999: Suzanne Cory; David L Vaux; Andreas Strasser; Alan W Harris; Jerry M Adams
Insights from Bcl-2 and Myc: malignancy involves abrogation of apoptosis as well as sustained proliferation.
Cancer research 1999;59(7 Suppl):1685s-1692s.
1999: Jerry M Adams; David C S Huang; Hamsa Puthalakath; Philippe Bouillet; G Vairo; K Moriishi; George Hausmann; Lorraine A O'Reilly; K Newton; Sarah Ogilvy; Mary L Bath; Cristin G Print; Alan W Harris; Andreas Strasser; Suzanne Cory
Control of apoptosis in hematopoietic cells by the Bcl-2 family of proteins.
Cold Spring Harbor symposia on quantitative biology 1999;64():351-8.
1999: K M Innes; S J Szilvassy; H E Davidson; L Gibson; Jerry M Adams; Suzanne Cory
Retroviral transduction of enriched hematopoietic stem cells allows lifelong Bcl-2 expression in multiple lineages but does not perturb hematopoiesis.
Experimental hematology 1999;27(1):75-87.
1998: Cristin G Print; Kate L Loveland; L Gibson; Terri Meehan; A Stylianou; Nigel G Wreford; David M de Kretser; Donald Metcalf; F Köntgen; Jerry M Adams; Suzanne Cory
Apoptosis regulator bcl-w is essential for spermatogenesis but appears otherwise redundant.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(21):12424-31.
1998: David C S Huang; Jerry M Adams; Suzanne Cory
The conserved N-terminal BH4 domain of Bcl-2 homologues is essential for inhibition of apoptosis and interaction with CED-4.
The EMBO journal 1998;17(4):1029-39.
1998: L O'Connor; Andreas Strasser; Lorraine A O'Reilly; George Hausmann; Jerry M Adams; Suzanne Cory; David C S Huang
Bim: a novel member of the Bcl-2 family that promotes apoptosis.
The EMBO journal 1998;17(2):384-95.
1998: Sarah Ogilvy; Andrew G Elefanty; Jane E Visvader; Mary L Bath; Alan W Harris; Jerry M Adams
Transcriptional regulation of vav, a gene expressed throughout the hematopoietic compartment.
Blood 1998;91(2):419-30.
1997: Jerry M Adams
Whitehead Symposium on cancer.
Biochimica et biophysica acta 1997;1332(2):R15-9.
1996: G Vairo; K M Innes; Jerry M Adams
Bcl-2 has a cell cycle inhibitory function separable from its enhancement of cell survival.
Oncogene 1996;13(7):1511-9.
1996: Andreas Strasser; L O'Connor; David C S Huang; Lorraine A O'Reilly; M L Stanley; Mary L Bath; Jerry M Adams; Suzanne Cory; Alan W Harris
Lessons from bcl-2 transgenic mice for immunology, cancer biology and cell death research.
Behring Institute Mitteilungen 1996;(97):101-17.
1996: L Gibson; S P Holmgreen; David C S Huang; O Bernard; N G Copeland; N A Jenkins; G R Sutherland; E Baker; Jerry M Adams; Suzanne Cory
bcl-w, a novel member of the bcl-2 family, promotes cell survival.
Oncogene 1996;13(4):665-75.
1996: B Hentsch; I Lyons; R Li; Lynne Hartley; T J Lints; Jerry M Adams; Richard P Harvey
Hlx homeo box gene is essential for an inductive tissue interaction that drives expansion of embryonic liver and gut.
Genes & development 1996;10(1):70-9.
1995: T Metz; Alan W Harris; Jerry M Adams
Absence of p53 allows direct immortalization of hematopoietic cells by the myc and raf oncogenes.
Cell 1995;82(1):29-36.
1995: G J Lindeman; Alan W Harris; Mary L Bath; Robert N Eisenman; Jerry M Adams
Overexpressed max is not oncogenic and attenuates myc-induced lymphoproliferation and lymphomagenesis in transgenic mice.
Oncogene 1995;10(5):1013-7.
1995: J D Allen; Alan W Harris; Mary L Bath; Andreas Strasser; Roland Scollay; Jerry M Adams
Perturbed development of T and B cells in mice expressing an Hlx homeobox transgene.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(4):1531-42.
1995: J E Visvader; M Crossley; J Hill; Stuart H Orkin; Jerry M Adams
The C-terminal zinc finger of GATA-1 or GATA-2 is sufficient to induce megakaryocytic differentiation of an early myeloid cell line.
Molecular and cellular biology 1995;15(2):634-41.
1995: Alan W Harris; S E Bodrug; B J Warner; Mary L Bath; G J Lindeman; Jerry M Adams
Cyclin D1 as the putative bcl-1 oncogene.
Current topics in microbiology and immunology 1995;194():347-53.
1994: G J Lindeman; Jerry M Adams; S Cory; Alan W Harris
B-lymphoid to granulocytic switch during hematopoiesis in a transgenic mouse strain.
Immunity 1994;1(6):517-27.
1994: S E Bodrug; B J Warner; Mary L Bath; G J Lindeman; Alan W Harris; Jerry M Adams
Cyclin D1 transgene impedes lymphocyte maturation and collaborates in lymphomagenesis with the myc gene.
The EMBO journal 1994;13(9):2124-30.
1994: Suzanne Cory; Andreas Strasser; T Jacks; L M Corcoran; T Metz; Alan W Harris; Jerry M Adams
Enhanced cell survival and tumorigenesis.
Cold Spring Harbor symposia on quantitative biology 1994;59():365-75.
1993: Y Haupt; Mary L Bath; Alan W Harris; Jerry M Adams
bmi-1 transgene induces lymphomas and collaborates with myc in tumorigenesis.
Oncogene 1993;8(11):3161-4.
1993: Y Haupt; Alan W Harris; Jerry M Adams
Moloney virus induction of T-cell lymphomas in a plasmacytomagenic strain of E mu-v-abl transgenic mice.
International journal of cancer. Journal international du cancer 1993;55(4):623-9.
1993: J Visvader; Jerry M Adams
Megakaryocytic differentiation induced in 416B myeloid cells by GATA-2 and GATA-3 transgenes or 5-azacytidine is tightly coupled to GATA-1 expression.
Blood 1993;82(5):1493-501.
1993: J D Allen; Jerry M Adams
Enforced expression of Hlx homeobox gene prompts myeloid cell maturation and altered adherence properties of T cells.
Blood 1993;81(12):3242-51.
1992: J E Visvader; Andrew G Elefanty; Andreas Strasser; Jerry M Adams
GATA-1 but not SCL induces megakaryocytic differentiation in an early myeloid line.
The EMBO journal 1992;11(12):4557-64.
1992: Y Haupt; G Barri; Jerry M Adams
Nucleotide sequence of bup, an upstream gene in the bmi-1 proviral insertion locus.
Molecular biology reports 1992;17(1):17-20.
1992: Y Haupt; Alan W Harris; Jerry M Adams
Retroviral infection accelerates T lymphomagenesis in E mu-N-ras transgenic mice by activating c-myc or N-myc.
Oncogene 1992;7(5):981-6.
1992: Jerry M Adams; H Houston; J Allen; T Lints; R Harvey
The hematopoietically expressed vav proto-oncogene shares homology with the dbl GDP-GTP exchange factor, the bcr gene and a yeast gene (CDC24) involved in cytoskeletal organization.
Oncogene 1992;7(4):611-8.
1992: Jerry M Adams; Suzanne Cory
Oncogene co-operation in leukaemogenesis.
Cancer surveys 1992;15():119-41.
1991: Jerry M Adams; Suzanne Cory
Transgenic models of tumor development.
Science (New York, N.Y.) 1991;254(5035):1161-7.
1991: Andreas Strasser; S Whittingham; David L Vaux; Mary L Bath; Jerry M Adams; Suzanne Cory; Alan W Harris
Enforced BCL2 expression in B-lymphoid cells prolongs antibody responses and elicits autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(19):8661-5.
1991: Y Haupt; Warren S Alexander; G Barri; S P Klinken; Jerry M Adams
Novel zinc finger gene implicated as myc collaborator by retrovirally accelerated lymphomagenesis in E mu-myc transgenic mice.
Cell 1991;65(5):753-63.
1991: Jerry M Adams; Suzanne Cory
Transgenic models for haemopoietic malignancies.
Biochimica et biophysica acta 1991;1072(1):9-31.
1991: J D Allen; T Lints; N A Jenkins; N G Copeland; Andreas Strasser; Richard P Harvey; Jerry M Adams
Novel murine homeo box gene on chromosome 1 expressed in specific hematopoietic lineages and during embryogenesis.
Genes & development 1991;5(4):509-20.
1991: J Visvader; C Glenn Begley; Jerry M Adams
Differential expression of the LYL, SCL and E2A helix-loop-helix genes within the hemopoietic system.
Oncogene 1991;6(2):187-94.
1990: A Perkins; K Kongsuwan; J Visvader; Jerry M Adams; Suzanne Cory
Homeobox gene expression plus autocrine growth factor production elicits myeloid leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(21):8398-402.
1990: Jerry M Adams
Growth control circuitry and the oncogene connection.
Cancer cells (Cold Spring Harbor, N.Y. : 1989) 1990;2(6):190-2.
1990: H Rosenbaum; Alan W Harris; Mary L Bath; J McNeall; E Webb; Jerry M Adams; Suzanne Cory
An E mu-v-abl transgene elicits plasmacytomas in concert with an activated myc gene.
The EMBO journal 1990;9(3):897-905.
1990: Andreas Strasser; Alan W Harris; David L Vaux; E Webb; Mary L Bath; Jerry M Adams; Suzanne Cory
Abnormalities of the immune system induced by dysregulated bcl-2 expression in transgenic mice.
Current topics in microbiology and immunology 1990;166():175-81.
1990: Alan W Harris; Mary L Bath; H Rosenbaum; J McNeall; Jerry M Adams; Suzanne Cory
Lymphoid tumorigenesis by v-abl and BCR-v-abl in transgenic mice.
Current topics in microbiology and immunology 1990;166():165-73.
1989: E Webb; G Barri; Suzanne Cory; Jerry M Adams
Lymphomagenesis in Emu-myc transgenic mice does not require transgene rearrangement or mutation of myc exon 1.
Molecular biology & medicine 1989;6(6):475-80.
1989: I K Hariharan; Alan W Harris; M Crawford; H Abud; E Webb; Suzanne Cory; Jerry M Adams
A bcr-v-abl oncogene induces lymphomas in transgenic mice.
Molecular and cellular biology 1989;9(7):2798-805.
1989: Warren S Alexander; O Bernard; Suzanne Cory; Jerry M Adams
Lymphomagenesis in E mu-myc transgenic mice can involve ras mutations.
Oncogene 1989;4(5):575-81.
1989: K Kongsuwan; J Allen; Jerry M Adams
Expression of Hox-2.4 homeobox gene directed by proviral insertion in a myeloid leukemia.
Nucleic acids research 1989;17(5):1881-92.
1989: H Rosenbaum; E Webb; Jerry M Adams; Suzanne Cory; Alan W Harris
N-myc transgene promotes B lymphoid proliferation, elicits lymphomas and reveals cross-regulation with c-myc.
The EMBO journal 1989;8(3):749-55.
1989: Warren S Alexander; Jerry M Adams; Suzanne Cory
Oncogene cooperation in lymphocyte transformation: malignant conversion of E mu-myc transgenic pre-B cells in vitro is enhanced by v-H-ras or v-raf but not v-abl.
Molecular and cellular biology 1989;9(1):67-73.
1989: Warren S Alexander; O Bernard; W Y Langdon; Alan W Harris; Jerry M Adams; Suzanne Cory
Oncogene cooperation and B-lymphoid tumorigenesis in Emu-myc transgenic mice.
Haematology and blood transfusion 1989;32():423-7.
1989: I K Hariharan; G R Johnson; Thomas J Gonda; Donald Metcalf; Jerry M Adams; Suzanne Cory
Analysis of the leukemogenic properties of the bcr-v-abl and GM-CSF genes using a new retroviral vector.
Current topics in microbiology and immunology 1989;149():99-107.
1989: Jerry M Adams; Alan W Harris; W Y Langdon; S P Klinken; K Kongsuwan; Warren S Alexander; I Hariharan; David L Vaux; H Rosenbaum; M Crawford
Lymphoid neoplasia and the control of haemopoietic differentiation.
Ciba Foundation symposium 1989;142():54-64; discussion 65-70.
1989: Jerry M Adams; Alan W Harris; David L Vaux; Warren S Alexander; H Rosenbaum; S P Klinken; Andreas Strasser; Mary L Bath; J McNeall; Suzanne Cory
The transgenic window on lymphoid malignancy.
Princess Takamatsu symposia 1989;20():297-309.
1988: David L Vaux; Suzanne Cory; Jerry M Adams
Bcl-2 gene promotes haemopoietic cell survival and cooperates with c-myc to immortalize pre-B cells.
Nature 1988;335(6189):440-2.
1988: K Kongsuwan; E Webb; P Housiaux; Jerry M Adams
Expression of multiple homeobox genes within diverse mammalian haemopoietic lineages.
The EMBO journal 1988;7(7):2131-8.
1988: S P Klinken; Warren S Alexander; Jerry M Adams
Hemopoietic lineage switch: v-raf oncogene converts Emu-myc transgenic B cells into macrophages.
Cell 1988;53(6):857-67.
1988: Alan W Harris; C A Pinkert; M Crawford; W Y Langdon; R L Brinster; Jerry M Adams
The E mu-myc transgenic mouse. A model for high-incidence spontaneous lymphoma and leukemia of early B cells.
The Journal of experimental medicine 1988;167(2):353-71.
1988: I K Hariharan; Jerry M Adams; Suzanne Cory
bcr-abl oncogene renders myeloid cell line factor independent: potential autocrine mechanism in chronic myeloid leukemia.
Oncogene research 1988;3(4):387-99.
1988: Steve Gerondakis; O Bernard; Suzanne Cory; Jerry M Adams
Immunoglobulin JH rearrangement in a T-cell line reflects fusion to the DH locus at a sequence lacking the nonamer recognition signal.
Immunogenetics 1988;28(4):255-9.
1988: Suzanne Cory; Jerry M Adams
Transgenic mice and oncogenesis.
Annual review of immunology 1988;6():25-48.
1987: D L Vaux; Jerry M Adams; Warren S Alexander; B L Pike
Immunologic competence of B cells subjected to constitutive c-myc oncogene expression in immunoglobulin heavy chain enhancer myc transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 1987;139(11):3854-60.
1987: Suzanne Cory; Alan W Harris; W Y Langdon; Warren S Alexander; L M Corcoran; R D Palmiter; C A Pinkert; R L Brinster; Jerry M Adams
The myc oncogene and lymphoid neoplasia: from translocations to transgenic mice.
Haematology and blood transfusion 1987;31():248-51.
1986: Jerry M Adams; Alan W Harris; W Y Langdon; C A Pinkert; R L Brinster; R D Palmiter; L Corcoran; Warren S Alexander; M W Graham; Suzanne Cory
c-myc-induced lymphomagenesis in transgenic mice and the role of the Pvt-1 locus in lymphoid neoplasia.
Current topics in microbiology and immunology 1986;132():1-8.
1983: Suzanne Cory; Jerry M Adams; Steve Gerondakis; J F Miller; J Gamble; F Wiener; J Spira; U Francke
Fusion of DNA region to murine immunoglobulin heavy chain locus corresponds to plasmacytoma-associated chromosome translocation.
The EMBO journal 1983;2(2):213-6.