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Tatsuya Kondo

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Cullen M Taniguchi; Jonathon Winnay; Tatsuya Kondo; Roderick T Bronson; Alexander R Guimaraes; José O Alemán; Ji Luo; Gregory Stephanopoulos; Ralph Weissleder; Lewis C Cantley; C Ronald Kahn
The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Victoria Rotter Sopasakis; Pixu Liu; Ryo Suzuki; Tatsuya Kondo; Jonathon Winnay; Thien T Tran; Tomoichiro Asano; Graham Smyth; Mini P Sajan; Robert V Farese; C Ronald Kahn; Jean J Zhao
Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation.
Cullen M Taniguchi; Thien Tran; Tatsuya Kondo; Ji Luo; Kohjiro Ueki; Lewis C Cantley; C Ronald Kahn
Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.

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All Publications

2010: Cullen M Taniguchi; Jonathon Winnay; Tatsuya Kondo; Roderick T Bronson; Alexander R Guimaraes; José O Alemán; Ji Luo; Gregory Stephanopoulos; Ralph Weissleder; Lewis C Cantley; C Ronald Kahn
The phosphoinositide 3-kinase regulatory subunit p85alpha can exert tumor suppressor properties through negative regulation of growth factor signaling.
Cancer research 2010;70(13):5305-15.
2010: Victoria Rotter Sopasakis; Pixu Liu; Ryo Suzuki; Tatsuya Kondo; Jonathon Winnay; Thien T Tran; Tomoichiro Asano; Graham Smyth; Mini P Sajan; Robert V Farese; C Ronald Kahn; Jean J Zhao
Specific roles of the p110alpha isoform of phosphatidylinsositol 3-kinase in hepatic insulin signaling and metabolic regulation.
Cell metabolism 2010;11(3):220-30.
2006: Cullen M Taniguchi; Thien Tran; Tatsuya Kondo; Ji Luo; Kohjiro Ueki; Lewis C Cantley; C Ronald Kahn
Phosphoinositide 3-kinase regulatory subunit p85alpha suppresses insulin action via positive regulation of PTEN.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(32):12093-7.
2006: Konstantinos B Sotiropoulos; Allen Clermont; Yutaka Yasuda; Christian Rask-Madsen; Motonobu Mastumoto; Junichi Takahashi; Kim Della Vecchia; Tatsuya Kondo; Lloyd Paul Aiello; George L King
Adipose-specific effect of rosiglitazone on vascular permeability and protein kinase C activation: novel mechanism for PPARgamma agonist's effects on edema and weight gain.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2006;20(8):1203-5.
2006: Cullen M Taniguchi; Tatsuya Kondo; Mini P Sajan; Ji Luo; Roderick Bronson; Tomoichiro Asano; Robert Farese; Lewis C Cantley; C Ronald Kahn
Divergent regulation of hepatic glucose and lipid metabolism by phosphoinositide 3-kinase via Akt and PKClambda/zeta.
Cell metabolism 2006;3(5):343-53.
2004: Tatsuya Kondo; C Ronald Kahn
Altered insulin signaling in retinal tissue in diabetic states.
The Journal of biological chemistry 2004;279(36):37997-8006.
2004: Kohjiro Ueki; Tatsuya Kondo; Yu-Hua Tseng; C Ronald Kahn
Central role of suppressors of cytokine signaling proteins in hepatic steatosis, insulin resistance, and the metabolic syndrome in the mouse.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(28):10422-7.
2004: Kohjiro Ueki; Tatsuya Kondo; C Ronald Kahn
Suppressor of cytokine signaling 1 (SOCS-1) and SOCS-3 cause insulin resistance through inhibition of tyrosine phosphorylation of insulin receptor substrate proteins by discrete mechanisms.
Molecular and cellular biology 2004;24(12):5434-46.
2004: Tatsuya Kondo; Ali Hafezi-Moghadam; Kennard Thomas; Denisa D Wagner; C Ronald Kahn
Mice lacking insulin or insulin-like growth factor 1 receptors in vascular endothelial cells maintain normal blood-brain barrier.
Biochemical and biophysical research communications 2004;317(2):315-20.
2003: Tatsuya Kondo; David Vicent; Kiyoshi Suzuma; Masashi Yanagisawa; George L King; Martin Holzenberger; C Ronald Kahn
Knockout of insulin and IGF-1 receptors on vascular endothelial cells protects against retinal neovascularization.
The Journal of clinical investigation 2003;111(12):1835-42.
2003: David Vicent; Jacob Ilany; Tatsuya Kondo; Keiko Naruse; Simon J Fisher; Yaz Y Kisanuki; Sven-Erik Bursell; Masashi Yanagisawa; George L King; C Ronald Kahn
The role of endothelial insulin signaling in the regulation of vascular tone and insulin resistance.
The Journal of clinical investigation 2003;111(9):1373-80.