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Augustine Kong

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Iceland

Genes & Molecular Sequences

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Thorlakur Jonsson; Augustine Kong; James J Lah; Allan I Levey; Dan Rujescu; Jon Snaedal; Hreinn Stefansson; Ole A Andreassen; Sigurbjorn Bjornsson; Srdjan Djurovic; Knut Engedal; Ina Giegling; Harald Hampel; Albert Hofman; Johanna Huttenlocher; Carla Ibrahim-Verbaas; M Arfan Ikram; Ingileif Jonsdottir; Palmi V Jonsson; Stacy Steinberg; Unnur Thorsteinsdottir; Ingun Ulstein; Cornelia M van Duijn; Kari Stefansson
Variant of TREM2 associated with the risk of Alzheimer's disease.
Augustine Kong; Gisli Magnusson; Olafur Th Magnusson; Gisli Masson; Asgeir Sigurdsson; Gunnar Sigurdsson; Stacy Steinberg; Patrick Sulem; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Gudmundur Bragi Walters; Wendy S W Wong; Soren Besenbacher; Michael L Frigge; Daniel F Gudbjartsson; Sigurjon A Gudjonsson; Agnar Helgason; Hannes Helgason; Aslaug Jonasdottir; Adalbjorg Jonasdottir; kari stefansson
Rate of de novo mutations and the importance of father's age to disease risk.
Thorlakur Jonsson; Augustine Kong; Yichin Liu; Yanmei Lu; Olafur T Magnusson; Janice Maloney; Aarno Palotie; Jon Snaedal; Hreinn Stefansson; Ole A Andreassen; Jasvinder K Atwal; Timothy W Behrens; Tushar Bhangale; Gyda Bjornsdottir; Sigurbjorn Bjornsson; Robert R Graham; Daniel F Gudbjartsson; Amy Gustafson; Kwame Hoyte; Johanna Huttenlocher; Erik G Jönsson; Palmi V Jonsson; Stacy Steinberg; Patrick Sulem; Unnur Thorsteinsdottir; Ryan J Watts; kari stefansson
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.

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All Publications

2013: Thorlakur Jonsson; Augustine Kong; James J Lah; Allan I Levey; Dan Rujescu; Jon Snaedal; Hreinn Stefansson; Ole A Andreassen; Sigurbjorn Bjornsson; Srdjan Djurovic; Knut Engedal; Ina Giegling; Harald Hampel; Albert Hofman; Johanna Huttenlocher; Carla Ibrahim-Verbaas; M Arfan Ikram; Ingileif Jonsdottir; Palmi V Jonsson; Stacy Steinberg; Unnur Thorsteinsdottir; Ingun Ulstein; Cornelia M van Duijn; Kari Stefansson
Variant of TREM2 associated with the risk of Alzheimer's disease.
The New England journal of medicine 2013;368(2):107-16.
2012: Augustine Kong; Gisli Magnusson; Olafur Th Magnusson; Gisli Masson; Asgeir Sigurdsson; Gunnar Sigurdsson; Stacy Steinberg; Patrick Sulem; Gudmar Thorleifsson; Unnur Thorsteinsdottir; Gudmundur Bragi Walters; Wendy S W Wong; Soren Besenbacher; Michael L Frigge; Daniel F Gudbjartsson; Sigurjon A Gudjonsson; Agnar Helgason; Hannes Helgason; Aslaug Jonasdottir; Adalbjorg Jonasdottir; kari stefansson
Rate of de novo mutations and the importance of father's age to disease risk.
Nature 2012;488(7412):471-5.
2012: Thorlakur Jonsson; Augustine Kong; Yichin Liu; Yanmei Lu; Olafur T Magnusson; Janice Maloney; Aarno Palotie; Jon Snaedal; Hreinn Stefansson; Ole A Andreassen; Jasvinder K Atwal; Timothy W Behrens; Tushar Bhangale; Gyda Bjornsdottir; Sigurbjorn Bjornsson; Robert R Graham; Daniel F Gudbjartsson; Amy Gustafson; Kwame Hoyte; Johanna Huttenlocher; Erik G Jönsson; Palmi V Jonsson; Stacy Steinberg; Patrick Sulem; Unnur Thorsteinsdottir; Ryan J Watts; kari stefansson
A mutation in APP protects against Alzheimer's disease and age-related cognitive decline.
Nature 2012;488(7409):96-9.
2011: Patrick Sulem; Daniel F Gudbjartsson; Frank Geller; Inga Prokopenko; Bjarke Feenstra; Katja K H Aben; Barbara Franke; Martin den Heijer; Peter Kovacs; Michael Stumvoll; Reedik Mägi; Lisa R Yanek; Lewis C Becker; Heather A Boyd; Simon N Stacey; Gudmundur Bragi Walters; Adalbjorg Jonasdottir; Gudmar Thorleifsson; Hilma Holm; Sigurjon A Gudjonsson; Thorunn Rafnar; Gyda Björnsdottir; Diane M Becker; Mads Melbye; Augustine Kong; Anke Tönjes; Thorgeir Thorgeirsson; Unnur Thorsteinsdottir; Lambertus A Kiemeney; Kari Stefansson
Sequence variants at CYP1A1-CYP1A2 and AHR associate with coffee consumption.
Human molecular genetics 2011;20(10):2071-7.
2011: Hilma Holm; Daniel F Gudbjartsson; Patrick Sulem; Gisli Masson; Hafdis Th Helgadottir; Carlo Zanon; Olafur Th Magnusson; Agnar Helgason; Jona Saemundsdottir; Arnaldur Gylfason; Hrafnhildur Stefansdottir; Solveig Gretarsdottir; Stefan E Matthiasson; Gu Mundur Thorgeirsson; Aslaug Jonasdottir; Asgeir Sigurdsson; Hreinn Stefansson; Thomas Werge; Thorunn Rafnar; Lambertus A Kiemeney; Babar Parvez; Raafia Muhammad; Dan Mark Roden; Dawood Darbar; Gudmar Thorleifsson; Gudmundur Bragi Walters; Augustine Kong; Unnur Thorsteinsdottir; David O Arnar; kari stefansson
A rare variant in MYH6 is associated with high risk of sick sinus syndrome.
Nature genetics 2011;43(4):316-20.
2011: Alkes L Price; Agnar Helgason; Gudmar Thorleifsson; Steven A McCarroll; Augustine Kong; Kari Stefansson
Single-tissue and cross-tissue heritability of gene expression via identity-by-descent in related or unrelated individuals.
PLoS genetics 2011;7(2):e1001317.
2010: Augustine Kong; Gudmar Thorleifsson; Daniel F Gudbjartsson; Gisli Masson; Asgeir Sigurdsson; Aslaug Jonasdottir; Gudmundur Bragi Walters; Adalbjorg Jonasdottir; Arnaldur Gylfason; Kari Th Kristinsson; Sigurjon A Gudjonsson; Michael L Frigge; Agnar Helgason; Unnur Thorsteinsdottir; kari stefansson
Fine-scale recombination rate differences between sexes, populations and individuals.
Nature 2010;467(7319):1099-103.
2010: Daniel F Gudbjartsson; Hilma Holm; Olafur S Indridason; Gudmar Thorleifsson; Vidar Edvardsson; Patrick Sulem; Femmie de Vegt; Frank C H d'Ancona; Martin den Heijer; Jack F M Wetzels; Leifur Franzson; Thorunn Rafnar; Kristleifur Kristjansson; Unnur S Bjornsdottir; Gudmundur I Eyjolfsson; Lambertus A Kiemeney; Augustine Kong; Runolfur Palsson; Unnur Thorsteinsdottir; kari stefansson
Association of variants at UMOD with chronic kidney disease and kidney stones-role of age and comorbid diseases.
PLoS genetics 2010;6(7):e1001039.
2010: Hilma Holm; Daniel F Gudbjartsson; David O Arnar; Gudmar Thorleifsson; Gudmundur Thorgeirsson; Hrafnhildur Stefansdottir; Sigurjon A Gudjonsson; Aslaug Jonasdottir; Ellisiv B Mathiesen; Inger Njølstad; Audhild Nyrnes; Tom Wilsgaard; Erin M Hald; Kristian Hveem; Camilla Stoltenberg; Maja-Lisa Løchen; Augustine Kong; Unnur Thorsteinsdottir; kari stefansson
Several common variants modulate heart rate, PR interval and QRS duration.
Nature genetics 2010;42(2):117-22.
2010: Unnur Styrkarsdottir; Bjarni V Halldorsson; Daniel F Gudbjartsson; Nelson L S Tang; Jung-Min Koh; Su-mei Xiao; Timothy C Y Kwok; Ghi Su Kim; Juliana C N Chan; Stacey Cherny; Seung Hun Lee; Anthony Kwok; Suzanne Ho; Solveig Gretarsdottir; Jelena Pop Kostic; Stefan Th Palsson; Gunnar Sigurdsson; Pak C Sham; Beom-Jun Kim; Annie W C Kung; Shin-Yoon Kim; Jean Woo; Ping-C Leung; Augustine Kong; Unnur Thorsteinsdottir; Kari Stefansson
European bone mineral density loci are also associated with BMD in East-Asian populations.
PloS one 2010;5(10):e13217.
2009: Augustine Kong; Valgerdur Steinthorsdottir; Gisli Masson; Gudmar Thorleifsson; Patrick Sulem; Soren Besenbacher; Aslaug Jonasdottir; Asgeir Sigurdsson; Kari Th Kristinsson; Aslaug Jonasdottir; Michael L Frigge; Arnaldur Gylfason; Pall I Olason; Sigurjon A Gudjonsson; Sverrir Sverrisson; Simon N Stacey; Bardur Sigurgeirsson; Kristrun R Benediktsdottir; Helgi Sigurdsson; Thorlakur Jonsson; Rafn Benediktsson; Jon H Olafsson; Oskar Th Johannsson; Astradur B Hreidarsson; Gunnar Sigurdsson; Anne C Ferguson-Smith; Daniel F Gudbjartsson; Unnur Thorsteinsdottir; kari stefansson
Parental origin of sequence variants associated with complex diseases.
Nature 2009;462(7275):868-74.
2009: Gudmar Thorleifsson; Hilma Holm; Vidar Edvardsson; Gudmundur Bragi Walters; Unnur Styrkarsdottir; Daniel F Gudbjartsson; Patrick Sulem; Bjarni V Halldorsson; Femmie de Vegt; Frank C H d'Ancona; Martin den Heijer; Leifur Franzson; Claus Christiansen; Peter Alexandersen; Thorunn Rafnar; Kristleifur Kristjansson; Gunnar Sigurdsson; Lambertus A L M Kiemeney; Magnus Bodvarsson; Olafur S Indridason; Runolfur Palsson; Augustine Kong; Unnur Thorsteinsdottir; kari stefansson
Sequence variants in the CLDN14 gene associate with kidney stones and bone mineral density.
Nature genetics 2009;41(8):926-30.
2009: Alkes L Price; Agnar Helgason; Snaebjorn Palsson; Hreinn Stefansson; David St Clair; Ole A Andreassen; David Reich; Augustine Kong; kari stefansson
The impact of divergence time on the nature of population structure: an example from Iceland.
PLoS genetics 2009;5(6):e1000505.
2009: Patrick Sulem; Daniel F Gudbjartsson; Thorunn Rafnar; Hilma Holm; Elinborg J Olafsdottir; Gudridur H Olafsdottir; Thorvaldur Jonsson; Peter Alexandersen; Bjarke Feenstra; Heather A Boyd; Katja K Aben; Andre L M Verbeek; Nel Roeleveld; Aslaug Jonasdottir; Unnur Styrkarsdottir; Valgerdur Steinthorsdottir; Ari Karason; Simon N Stacey; Julius Gudmundsson; Margret Jakobsdottir; Gudmar Thorleifsson; Gudmundur Hardarson; Jeffrey R Gulcher; Augustine Kong; Lambertus A L M Kiemeney; Mads Melbye; Claus Christiansen; Laufey Tryggvadottir; Unnur Thorsteinsdottir; kari stefansson
Genome-wide association study identifies sequence variants on 6q21 associated with age at menarche.
Nature genetics 2009;41(6):734-8.
2009: Hreinn Stefansson; Stacy Steinberg; Hjorvar Petursson; Omar Gustafsson; Iris H Gudjonsdottir; Gudrun A Jonsdottir; Stefan T Palsson; Thorlakur Jonsson; Jona Saemundsdottir; Gyda Bjornsdottir; Yvonne Böttcher; Theodora Thorlacius; Dietrich Haubenberger; Alexander Zimprich; Eduard Auff; Christoph Hotzy; Claudia M Testa; Lisa A Miyatake; Ami R Rosen; Kristleifur Kristleifsson; David Rye; Friedrich Asmus; Ludger Schöls; Martin Dichgans; Finnbogi Jakobsson; John Benedikz; Unnur Thorsteinsdottir; Jeffrey R Gulcher; Augustine Kong; kari stefansson
Variant in the sequence of the LINGO1 gene confers risk of essential tremor.
Nature genetics 2009;41(3):277-9.
2009: Unnur Styrkarsdottir; Bjarni V Halldorsson; Solveig Gretarsdottir; Daniel F Gudbjartsson; Gudmundur Bragi Walters; Thorvaldur Ingvarsson; Thorbjorg Jonsdottir; Jona Saemundsdottir; Steinunn Snorradóttir; Jacqueline R Center; Tuan V Nguyen; Peter Alexandersen; Jeffrey R Gulcher; John A Eisman; Claus Christiansen; Gunnar Sigurdsson; Augustine Kong; Unnur Thorsteinsdottir; Kari Stefansson
New sequence variants associated with bone mineral density.
Nature genetics 2009;41(1):15-7.
2008: J Brent Richards; Xin Yuan; Frank Geller; Dawn Waterworth; Veronique Bataille; Daniel Glass; Kijoung Song; Gerard Waeber; Peter Vollenweider; Katja K H Aben; Lambertus A Kiemeney; Gudmundur Bragi Walters; Nicole Soranzo; Unnur Thorsteinsdottir; Augustine Kong; Thorunn Rafnar; Panos Deloukas; Patrick Sulem; Hreinn Stefansson; Kari Stefansson; Tim D Spector; Vincent Mooser
Male-pattern baldness susceptibility locus at 20p11.
Nature genetics 2008;40(11):1282-4.
2008: Solveig Gretarsdottir; Gudmar Thorleifsson; Andrei Manolescu; Unnur Styrkarsdottir; Anna Helgadottir; Andreas Gschwendtner; Konstantinos Kostulas; Gregor Kuhlenbäumer; Steve Bevan; Thorbjorg Jonsdottir; Hjordis Bjarnason; Jona Saemundsdottir; Stefan Palsson; David O Arnar; Hilma Holm; Gudmundur Thorgeirsson; Einar Mar Valdimarsson; Sigurlaug Sveinbjörnsdottir; Christian Gieger; Klaus Berger; H-Erich Wichmann; Jan Hillert; Hugh Markus; Jeffrey R Gulcher; E Bernd Ringelstein; Augustine Kong; Martin Dichgans; Daniel Fannar Gudbjartsson; Unnur Thorsteinsdottir; Kari Stefansson
Risk variants for atrial fibrillation on chromosome 4q25 associate with ischemic stroke.
Annals of neurology 2008;64(4):402-9.
2008: Augustine Kong; Gisli Masson; Michael L Frigge; Arnaldur Gylfason; Pasha Zusmanovich; Gudmar Thorleifsson; Pall I Olason; Andres Ingason; Stacy Steinberg; Thorunn Rafnar; Patrick Sulem; Magali Mouy; Frosti Jonsson; Unnur Thorsteinsdottir; Daniel F Gudbjartsson; Hreinn Stefansson; kari stefansson
Detection of sharing by descent, long-range phasing and haplotype imputation.
Nature genetics 2008;40(9):1068-75.
2008: Patrick Sulem; Daniel F Gudbjartsson; Simon N Stacey; Agnar Helgason; Thorunn Rafnar; Margret Jakobsdottir; Stacy Steinberg; Sigurjon A Gudjonsson; Arnar Palsson; Gudmar Thorleifsson; Snaebjorn Palsson; Bardur Sigurgeirsson; Kristin Thorisdottir; Rafn Ragnarsson; Kristrun R Benediktsdottir; Katja K H Aben; Sita H Vermeulen; Alisa M Goldstein; Margaret A Tucker; Lambertus A L M Kiemeney; Jon H Olafsson; Jeffrey R Gulcher; Augustine Kong; Unnur Thorsteinsdottir; Kari Stefansson
Two newly identified genetic determinants of pigmentation in Europeans.
Nature genetics 2008;40(7):835-7.
2008: Unnur Styrkarsdottir; Bjarni V Halldorsson; Solveig Gretarsdottir; Daniel F Gudbjartsson; Gudmundur Bragi Walters; Thorvaldur Ingvarsson; Thorbjorg Jonsdottir; Jona Saemundsdottir; Jacqueline R Center; Tuan V Nguyen; Yu Bagger; Jeffrey R Gulcher; John A Eisman; Claus Christiansen; Gunnar Sigurdsson; Augustine Kong; Unnur Thorsteinsdottir; Kari Stefansson
Multiple genetic loci for bone mineral density and fractures.
The New England journal of medicine 2008;358(22):2355-65.
2008: Augustine Kong; Gudmar Thorleifsson; Hreinn Stefansson; Gisli Masson; Agnar Helgason; Daniel F Gudbjartsson; Gudrun M Jonsdottir; Sigurjon A Gudjonsson; Sverrir Sverrisson; Theodora Thorlacius; Aslaug Jonasdottir; Gudmundur A Hardarson; Stefan T Palsson; Michael L Frigge; Jeffrey R Gulcher; Unnur Thorsteinsdottir; Kari Stefansson
Sequence variants in the RNF212 gene associate with genome-wide recombination rate.
Science (New York, N.Y.) 2008;319(5868):1398-401.
2007: Patrick Sulem; Daniel F Gudbjartsson; Simon N Stacey; Agnar Helgason; Thorunn Rafnar; Kristinn Magnusson; Andrei Manolescu; Ari Karason; Arnar Palsson; Gudmar Thorleifsson; Margret Jakobsdottir; Stacy Steinberg; Snaebjorn Palsson; Fridbert Jonasson; Bardur Sigurgeirsson; Kristin Thorisdottir; Rafn Ragnarsson; Kristrun R Benediktsdottir; Katja K H Aben; Lambertus A L M Kiemeney; Jon H Olafsson; Jeffrey R Gulcher; Augustine Kong; Unnur Thorsteinsdottir; Kari Stefansson
Genetic determinants of hair, eye and skin pigmentation in Europeans.
Nature genetics 2007;39(12):1443-52.
2007: Gudmar Thorleifsson; Kristinn Magnusson; Patrick Sulem; Gudmundur Bragi Walters; Daniel F Gudbjartsson; Hreinn Stefansson; Thorlakur Jonsson; Aslaug Jonasdottir; Aslaug Jonasdottir; Gerdur Stefansdottir; Gisli Masson; Gudmundur A Hardarson; Hannes Petursson; Arsaell Arnarsson; Mehdi Motallebipour; Ola Wallerman; Claes Wadelius; Jeffrey R Gulcher; Unnur Thorsteinsdottir; Augustine Kong; Fridbert Jonasson; Kari Stefansson
Common sequence variants in the LOXL1 gene confer susceptibility to exfoliation glaucoma.
Science (New York, N.Y.) 2007;317(5843):1397-400.
2007: Andres Ingason; Thordur Sigmundsson; Stacy Steinberg; Engilbert Sigurdsson; Magnus Haraldsson; Brynja B Magnusdottir; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Unnur Thorsteinsdottir; Kari Stefansson; Hannes Petursson; Hreinn Stefansson
Support for involvement of the AHI1 locus in schizophrenia.
European journal of human genetics : EJHG 2007;15(9):988-91.
2007: Hreinn Stefansson; David B Rye; Andrew Hicks; Hannes Petursson; Andres Ingason; Thorgeir E Thorgeirsson; Stefan T Palsson; Thordur Sigmundsson; Albert P Sigurdsson; Ingibjorg Eiriksdottir; Emilia Soebech; Donald L Bliwise; Joseph M Beck; Ami Rosen; Salina Waddy; Lynn M Trotti; Isabel San Andres; Madhav Thambisetty; Gudmundur A Hardarson; Kristleifur Kristjansson; Larus J Gudmundsson; Unnur Thorsteinsdottir; Augustine Kong; Jeffrey R Gulcher; Daniel F Gudbjartsson; Kari Stefansson
A genetic risk factor for periodic limb movements in sleep.
The New England journal of medicine 2007;357(7):639-47.
2006: Simon N Stacey; Patrick Sulem; Oskar T Johannsson; Agnar Helgason; Julius Gudmundsson; Jelena P Kostic; Kristleifur Kristjansson; Thora Jonsdottir; Haraldur Sigurdsson; Jon Hrafnkelsson; Johann Heidar Johannsson; Thorarinn Sveinsson; Gardar Myrdal; Hlynur Niels Grimsson; Jon Thor Bergthorsson; Laufey T Amundadottir; Jeffrey R Gulcher; Unnur Thorsteinsdottir; Augustine Kong; Kari Stefansson
The BARD1 Cys557Ser variant and breast cancer risk in Iceland.
PLoS medicine 2006;3(7):e217.
2006: Struan F A Grant; Gudmar Thorleifsson; Inga Reynisdottir; Rafn Benediktsson; Andrei Manolescu; Jesus Sainz; Agnar Helgason; Hreinn Stefansson; Valur Emilsson; Anna Helgadottir; Unnur Styrkarsdottir; Kristinn Magnusson; Gudmundur Bragi Walters; Ebba Palsdottir; Thorbjorg Jonsdottir; Thorunn Gudmundsdottir; Arnaldur Gylfason; Jona Saemundsdottir; Robert L Wilensky; Muredach P Reilly; Daniel J Rader; Yu Bagger; Claus Christiansen; Vilmundur Gudnason; Gunnar Sigurdsson; Unnur Thorsteinsdottir; Jeffrey R Gulcher; Augustine Kong; Kari Stefansson
Variant of transcription factor 7-like 2 (TCF7L2) gene confers risk of type 2 diabetes.
Nature genetics 2006;38(3):320-3.
2006: Kristinn Magnusson; Shan Duan; Haraldur Sigurdsson; Hannes Petursson; Zhenglin Yang; Yu Zhao; Paul S Bernstein; Jian Ge; Fridbert Jonasson; Einar Stefansson; Gudleif Helgadottir; Norman A Zabriskie; Thorlakur Jonsson; Asgeir Bjornsson; Theodora Thorlacius; Palmi V Jonsson; Gudmar Thorleifsson; Augustine Kong; Hreinn Stefansson; Kang Zhang; Kari Stefansson; Jeffrey R Gulcher
CFH Y402H confers similar risk of soft drusen and both forms of advanced AMD.
PLoS medicine 2006;3(1):e5.
2005: Daniel F Gudbjartsson; Thorvaldur Thorvaldsson; Augustine Kong; Gunnar Gunnarsson; Anna Ingolfsdottir
Allegro version 2.
Nature genetics 2005;37(10):1015-6.
2005: Solveig Gretarsdottir; Jeffrey R Gulcher; Gudmar Thorleifsson; Augustine Kong; Kari Stefansson
Comment on the phosphodiesterase 4D replication study by Bevan et al.
Stroke; a journal of cerebral circulation 2005;36(9):1824.
2005: Hakon Hakonarson; Sverrir Thorvaldsson; Anna Helgadottir; Daniel F Gudbjartsson; Florian Zink; Margret B Andresdottir; Andrei Manolescu; David O Arnar; Karl Andersen; Axel Sigurdsson; Gudmundur Thorgeirsson; Asgeir Jonsson; Uggi Agnarsson; Halldora Bjornsdottir; Gizur Gottskalksson; Atli Einarsson; Hrefna Gudmundsdottir; Asdis E Adalsteinsdottir; Kolbeinn Gudmundsson; Kristleifur Kristjansson; Thordur Hardarson; Arni Kristinsson; Eric J Topol; Jeffrey R Gulcher; Augustine Kong; Mark E Gurney; Gudmundur Thorgeirsson; Kari Stefansson
Effects of a 5-lipoxygenase-activating protein inhibitor on biomarkers associated with risk of myocardial infarction: a randomized trial.
JAMA : the journal of the American Medical Association 2005;293(18):2245-56.
2005: Anna Helgadottir; Solveig Gretarsdottir; David St Clair; Andrei Manolescu; J Cheung; Gudmar Thorleifsson; Alireza Pasdar; Struan F A Grant; lawrence whalley; Hakon Hakonarson; Unnur Thorsteinsdottir; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson; mary MAcleod
Association between the gene encoding 5-lipoxygenase-activating protein and stroke replicated in a Scottish population.
American journal of human genetics 2005;76(3):505-9.
2005: Hreinn Stefansson; Agnar Helgason; Gudmar Thorleifsson; Valgerdur Steinthorsdottir; Gisli Masson; John Barnard; Adam Baker; Aslaug Jonasdottir; Andres Ingason; Vala G Gudnadottir; Natasa Desnica; Andrew Hicks; Arnaldur Gylfason; Daniel F Gudbjartsson; Gudrun M Jonsdottir; Jesus Sainz; Kari Agnarsson; Birgitta Birgisdottir; Shyamali Ghosh; Adalheidur Olafsdottir; Jean-Baptiste Cazier; Kristleifur Kristjansson; Michael L Frigge; Thorgeir E Thorgeirsson; Jeffrey R Gulcher; Augustine Kong; Kari Stefansson
A common inversion under selection in Europeans.
Nature genetics 2005;37(2):129-37.
2004: Steinn Jonsson; Unnur Thorsteinsdottir; Daniel F Gudbjartsson; Hjortur H Jonsson; Kristleifur Kristjansson; Sigurdur Arnason; Vilmundur Gudnason; Helgi J Isaksson; Jonas Hallgrimsson; Jeffrey R Gulcher; Laufey T Amundadottir; Augustine Kong; Kari Stefansson
Familial risk of lung carcinoma in the Icelandic population.
JAMA : the journal of the American Medical Association 2004;292(24):2977-83.
2004: Laufey T Amundadottir; Sverrir Thorvaldsson; Daniel F Gudbjartsson; Patrick Sulem; Kristleifur Kristjansson; Sigurdur Arnason; Jeffrey R Gulcher; Johannes Bjornsson; Augustine Kong; Unnur Thorsteinsdottir; Kari Stefansson
Cancer as a complex phenotype: pattern of cancer distribution within and beyond the nuclear family.
PLoS medicine 2004;1(3):e65.
2004: Augustine Kong; John Barnard; Daniel F Gudbjartsson; Gudmar Thorleifsson; Gudrun M Jonsdottir; Sigrun Sigurdardottir; Bjorgvin Richardsson; Jonina Jonsdottir; Thorgeir E Thorgeirsson; Michael L Frigge; Neil E Lamb; Stephanie L Sherman; Jeffrey R Gulcher; Kari Stefansson
Recombination rate and reproductive success in humans.
Nature genetics 2004;36(11):1203-6.
2004: Dan L Nicolae; Augustine Kong
Measuring the relative information in allele-sharing linkage studies.
Biometrics 2004;60(2):368-75.
2004: Ragnheidur Fossdal; Fridbert Jonasson; Gudlaug Kristjansdottir; Augustine Kong; Hreinn Stefansson; Shyamali Gosh; Jeffrey R Gulcher; Kari Stefansson
A novel TEAD1 mutation is the causative allele in Sveinsson's chorioretinal atrophy (helicoid peripapillary chorioretinal degeneration).
Human molecular genetics 2004;13(9):975-81.
2004: Anna Helgadottir; Andrei Manolescu; Gudmar Thorleifsson; Solveig Gretarsdottir; Helga Jonsdottir; Unnur Thorsteinsdottir; Nilesh J Samani; Gudmundur Gudmundsson; Struan F A Grant; Gudmundur Thorgeirsson; Sigurlaug Sveinbjornsdottir; Einar M Valdimarsson; Stefan Matthiasson; Halldor Johannsson; Olof Gudmundsdottir; Mark E Gurney; Jesus Sainz; Margret Thorhallsdottir; Margret B Andresdottir; Michael L Frigge; Eric J Topol; Augustine Kong; Vilmundur Gudnason; Hakon Hakonarson; Jeffrey R Gulcher; Kari Stefansson
The gene encoding 5-lipoxygenase activating protein confers risk of myocardial infarction and stroke.
Nature genetics 2004;36(3):233-9.
2003: Unnur Styrkarsdottir; Jean-Baptiste Cazier; Augustine Kong; Ottar Rolfsson; Helene Larsen; Emma Bjarnadottir; Vala D Johannsdottir; Margret S Sigurdardottir; Yu Bagger; Claus Christiansen; Inga Reynisdottir; Struan F A Grant; Kristjan Jonasson; Michael L Frigge; Jeffrey R Gulcher; Gunnar Sigurdsson; Kari Stefansson
Linkage of osteoporosis to chromosome 20p12 and association to BMP2.
PLoS biology 2003;1(3):E69.
2003: Asgeir Bjornsson; Gudmundur Gudmundsson; Einar Gudfinnsson; María Hrafnsdóttir; John Benedikz; Svanhildur Skúladóttir; Kristleifur Kristjánsson; Michael L Frigge; Augustine Kong; Kári Stefánsson; Jeffrey R Gulcher
Localization of a gene for migraine without aura to chromosome 4q21.
American journal of human genetics 2003;73(5):986-93.
2003: Inga Reynisdottir; Gudmar Thorleifsson; Rafn Benediktsson; Gunnar Sigurdsson; Valur Emilsson; Anna Sigurlin Einarsdottir; Eyrun Edda Hjorleifsdottir; Gudbjorg Th Orlygsdottir; Gudrun Thora Bjornsdottir; Jona Saemundsdottir; Skarphedinn Halldorsson; Soffia Hrafnkelsdottir; Steinunn Bjorg Sigurjonsdottir; Svana Steinsdottir; Mitchell Martin; Jarema P Kochan; Brian K Rhees; Struan F A Grant; Michael L Frigge; Augustine Kong; Vilmundur Gudnason; Kari Stefansson; Jeffrey R Gulcher
Localization of a susceptibility gene for type 2 diabetes to chromosome 5q34-q35.2.
American journal of human genetics 2003;73(2):323-35.
2003: Stefán Einar Stefánsson; Hjörtur H Jónsson; Thorvaldur Ingvarsson; Ileana Manolescu; Hjörtur H Jónsson; Gudbjörg Olafsdóttir; Ebba Pálsdóttir; Gerdur Stefánsdóttir; Gudfinna Sveinbjörnsdóttir; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kári Stefánsson
Genomewide scan for hand osteoarthritis: a novel mutation in matrilin-3.
American journal of human genetics 2003;72(6):1448-59.
2003: Thorgeir E Thorgeirsson; Högni Oskarsson; Natasa Desnica; Jelena Pop Kostic; Jon G Stefansson; Halldor Kolbeinsson; Eirikur Lindal; Nikolai Gagunashvili; Michael L Frigge; Augustine Kong; Kari Stefansson; Jeffrey R Gulcher
Anxiety with panic disorder linked to chromosome 9q in Iceland.
American journal of human genetics 2003;72(5):1221-30.
2003: Hreinn Stefansson; Jane Sarginson; Augustine Kong; Phil Yates; Valgerdur Steinthorsdottir; Einar Gudfinnsson; Steinunn Gunnarsdottir; Nicholas Walker; Hannes Petursson; Caroline Crombie; Andres Ingason; Jeffrey R Gulcher; Kari Stefansson; David St Clair
Association of neuregulin 1 with schizophrenia confirmed in a Scottish population.
American journal of human genetics 2003;72(1):83-7.
2003: Ari Karason; Johann Gudjonsson; Ruchi Upmanyu; Arna A Antonsdottir; Valdimar B Hauksson; E Hjaltey Runasdottir; Hjortur H Jonsson; Daniel F Gudbjartsson; Michael L Frigge; Augustine Kong; Kari Stefansson; Helgi Valdimarsson; Jeffrey R Gulcher
A susceptibility gene for psoriatic arthritis maps to chromosome 16q: evidence for imprinting.
American journal of human genetics 2003;72(1):125-31.
2002: Andrew Hicks; Hjörvar Pétursson; Thorbjörn Jónsson; Hreinn Stefánsson; Hrefna S Jóhannsdóttir; Jesus Sainz; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kári Stefánsson; Sigurlaug Sveinbjörnsdóttir
A susceptibility gene for late-onset idiopathic Parkinson's disease.
Annals of neurology 2002;52(5):549-55.
2002: Thorarinn Gislason; Johann Heidar Johannsson; Asgeir Haraldsson; Berglind Ran Olafsdottir; Helga Jonsdottir; Augustine Kong; Michael L Frigge; Gudrun M Jonsdottir; Hakon Hakonarson; Jeffrey R Gulcher; Kari Stefansson
Familial predisposition and cosegregation analysis of adult obstructive sleep apnea and the sudden infant death syndrome.
American journal of respiratory and critical care medicine 2002;166(6):833-8.
2002: Hakon Hakonarson; Unnur S Bjornsdottir; Eva Halapi; Stefan T Palsson; Elva Adalsteinsdottir; David Gislason; Gudmundur Finnbogason; Thorarinn Gislason; Kristleifur Kristjansson; Thor Arnason; Illugi Birkisson; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson
A major susceptibility gene for asthma maps to chromosome 14q24.
American journal of human genetics 2002;71(3):483-91.
2002: Augustine Kong; Daniel F Gudbjartsson; Jesus Sainz; Gudrun M Jonsdottir; Sigurjon A Gudjonsson; Bjorgvin Richardsson; Sigrun Sigurdardottir; John Barnard; Bjorn Hallbeck; Gisli Masson; Adam Shlien; Stefan T Palsson; Michael L Frigge; Thorgeir E Thorgeirsson; Jeffrey R Gulcher; Kari Stefansson
A high-resolution recombination map of the human genome.
Nature genetics 2002;31(3):241-7.
2002: Kristleifur Kristjansson; Andrei Manolescu; Arni Kristinsson; Thordur Hardarson; Helga Knudsen; Sigurdur Ingason; Gudmar Thorleifsson; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson
Linkage of essential hypertension to chromosome 18q.
Hypertension 2002;39(6):1044-9.
2002: Hreinn Stefansson; Reynir T Geirsson; Valgerdur Steinthorsdottir; Hjortur H Jonsson; Andrei Manolescu; Augustine Kong; G Ingadottir; Jeffrey R Gulcher; Kari Stefansson
Genetic factors contribute to the risk of developing endometriosis.
Human reproduction (Oxford, England) 2002;17(3):555-9.
2002: Solveig Gretarsdottir; Sigurlaug Sveinbjörnsdottir; Hjortur H Jonsson; Finnbogi Jakobsson; Elisabet Einarsdottir; Uggi Agnarsson; Dana L Shkolny; Gudmundur Vikar Einarsson; Herdis M Gudjonsdottir; Einar M Valdimarsson; Olafur B Einarsson; Gudmundur Thorgeirsson; Radinka Hadzic; Sif Jonsdottir; Sigridur Th Reynisdottir; Sigrun M Bjarnadottir; Thorunn Gudmundsdottir; Gudrun J Gudlaugsdottir; Ramanjit Gill; Klaus Lindpaintner; Jesus Sainz; Helgi Hermann Hannesson; Gunnar Sigurdsson; Michael L Frigge; Augustine Kong; Vilmundur Gudnason; Kari Stefansson; Jeffrey R Gulcher
Localization of a susceptibility gene for common forms of stroke to 5q12.
American journal of human genetics 2002;70(3):593-603.
2002: Gudmundur Gudmundsson; Stefan Matthiasson; Haukur Arason; Halldor Johannsson; Freyr Runarsson; Hjördis Bjarnason; Katrin Helgadottir; Steinthora Thorisdottir; Gudrun Ingadottir; Klaus Lindpaintner; Jesus Sainz; Vilmundur Gudnason; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson
Localization of a gene for peripheral arterial occlusive disease to chromosome 1p31.
American journal of human genetics 2002;70(3):586-92.
2001: Hakon Hakonarson; Unnur S Bjornsdottir; E Ostermann; Thor Arnason; Asdis E Adalsteinsdottir; Eva Halapi; Dana L Shkolny; Kristleifur Kristjansson; S A Gudnadottir; Michael L Frigge; David Gislason; Thorarinn Gislason; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson
Allelic frequencies and patterns of single-nucleotide polymorphisms in candidate genes for asthma and atopy in Iceland.
American journal of respiratory and critical care medicine 2001;164(11):2036-44.
2001: Augusta M A Lachmeijer; Reynir Arngrímsson; E J Bastiaans; Michael L Frigge; Gerard Pals; S Sigurdardóttir; H Stéfansson; B Pálsson; D Nicolae; Augustine Kong; Jan G Aarnoudse; Jeffrey R Gulcher; Gustaaf A Dekker; Leo P ten Kate; K Stéfansson
A genome-wide scan for preeclampsia in the Netherlands.
European journal of human genetics : EJHG 2001;9(10):758-64.
2000: S Sveinbjörnsdottir; Andrew Hicks; Thorlakur Jonsson; H Pétursson; G Guğmundsson; Michael L Frigge; Augustine Kong; Jeffrey R Gulcher; Kari Stefansson
Familial aggregation of Parkinson's disease in Iceland.
The New England journal of medicine 2000;343(24):1765-70.
2000: Daniel F Gudbjartsson; K Jonasson; Michael L Frigge; Augustine Kong
Allegro, a new computer program for multipoint linkage analysis.
Nature genetics 2000;25(1):12-3.
1999: Reynir Arngrímsson; Michael L Frigge; Thorbjörn Jónsson; Hreinn Stefánsson; A Baldursdóttir; A S Einarsdóttir; B Palsson; S Snorradóttir; Augusta M A Lachmeijer; D Nicolae; Augustine Kong; Birkir Thor Bragason; Jeffrey R Gulcher; Reynir T Geirsson; R I Bjarnadóttir; S Sigurõardóttir; Kári Stefánsson
A genome-wide scan reveals a maternal susceptibility locus for pre-eclampsia on chromosome 2p13.
Human molecular genetics 1999;8(9):1799-805.
1999: Nancy J Cox; Michael L Frigge; Dan L Nicolae; Patrick Concannon; Craig L Hanis; Graeme I Bell; Augustine Kong
Loci on chromosomes 2 (NIDDM1) and 15 interact to increase susceptibility to diabetes in Mexican Americans.
Nature genetics 1999;21(2):213-5.
1997: Augustine Kong; Nancy J Cox
Allele-sharing models: LOD scores and accurate linkage tests.
American journal of human genetics 1997;61(5):1179-88.
1997: Augustine Kong; Michael L Frigge; G I Bell; E S Lander; Mark J Daly; N J Cox
Diabetes, dependence, asymptotics, selection and significance.
Nature genetics 1997;17(2):148.
1997: Jeffrey R Gulcher; P Jónsson; Augustine Kong; Kristleifur Kristjánsson; Michael L Frigge; A Kárason; I E Einarsdóttir; Hreinn Stefánsson; A S Einarsdóttir; S Sigurthoardóttir; S Baldursson; S Björnsdóttir; S M Hrafnkelsdóttir; Finnbogi Jakobsson; J Benedickz; Kári Stefánsson
Mapping of a familial essential tremor gene, FET1, to chromosome 3q13.
Nature genetics 1997;17(1):84-7.
1993: Augustine Kong; N Cox; Michael L Frigge; M Irwin
Sequential imputation and multipoint linkage analysis.
Genetic epidemiology 1993;10(6):483-8.
1992: Augustine Kong; Michael L Frigge; M Irwin; N Cox
Importance sampling. I. Computing multimodel p values in linkage analysis.
American journal of human genetics 1992;51(6):1413-29.
1992: Augustine Kong; Michael L Frigge; N Cox; W H Wong
Linkage analysis with adjustment for covariates: a method combining peeling with Gibbs sampling.
Cytogenetics and cell genetics 1992;59(2-3):208-10.
1991: Augustine Kong
Efficient methods for computing linkage likelihoods of recessive diseases in inbred pedigrees.
Genetic epidemiology 1991;8(2):81-103.