FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Frits Koning

Research Profile

Disorders

Celiac Disease

Chemicals & Drugs

Anatomy

Concepts & Ideas

Genes & Molecular Sequences

Amino Acid Sequences

Physiology

Co-author Network

Publications

TOP 3
Frederike Schmitz; Marco W J Schreurs; Frank J Staal; Allan Thompson; Jennifer M L Tjon; Jeroen Van Bergen; Hein W Verspaget; Yvonne Kooy-Winkelaar; Yuching Lai; Anton W Langerak; Richard J L F Lemmers; M Luisa Mearin; Chris J Mulder; Tom Cupedo; Frits Koning
Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II.
Jeroen Van Bergen; Melissa van Pel; David H Raulet; Christelle Retière; Daniela Salvatori; Allan Thompson; John Trowsdale; Frits Koning
HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model.
Frits Koning; Marieke Mol; M Luisa Mearin
The million-dollar question: is "gluten-free" food safe for patients with celiac disease?

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Frits Koning (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Frederike Schmitz; Marco W J Schreurs; Frank J Staal; Allan Thompson; Jennifer M L Tjon; Jeroen Van Bergen; Hein W Verspaget; Yvonne Kooy-Winkelaar; Yuching Lai; Anton W Langerak; Richard J L F Lemmers; M Luisa Mearin; Chris J Mulder; Tom Cupedo; Frits Koning
Identification of a potential physiological precursor of aberrant cells in refractory coeliac disease type II.
Gut 2013;62(4):509-19.
2013: Jeroen Van Bergen; Melissa van Pel; David H Raulet; Christelle Retière; Daniela Salvatori; Allan Thompson; John Trowsdale; Frits Koning
HLA reduces killer cell Ig-like receptor expression level and frequency in a humanized mouse model.
Journal of immunology (Baltimore, Md. : 1950) 2013;190(6):2880-5.
2013: Frits Koning; Marieke Mol; M Luisa Mearin
The million-dollar question: is "gluten-free" food safe for patients with celiac disease?
The American journal of clinical nutrition 2013;97(1):3-4.
2012: Jeroen Van Bergen; Henrike van Dongen; Floris A van Gaalen; Mariet C W Feltkamp; Tom W J Huizinga; René E M Toes; Frits Koning
Anticytomegalovirus seropositivity in rheumatoid arthritis is not associated with the presence of severe extraarticular complications: comment on the article by Pierer et al.
Arthritis and rheumatism 2012;64(8):2803-4; author reply 2804-5.
2012: Rob Mariman; Frits Koning; Bas Kremer; Tonny Lagerweij; Marjan van Erk; Lex Nagelkerken
Gene expression profiling identifies mechanisms of protection to recurrent trinitrobenzene sulfonic acid colitis mediated by probiotics.
Inflammatory bowel diseases 2012;18(8):1424-33.
2012: Frits Koning
Celiac disease: quantity matters.
Seminars in immunopathology 2012;34(4):541-9.
2012: Greetje J Tack; Jennifer M L Tjon; Jeroen Van Bergen; Roy L J van Wanrooij; B Mary E von Blomberg; Gerd Bouma; Danielle A M Heideman; Frits Koning; Anton W Langerak; Chris J J Mulder; Marco W J Schreurs
Origin and immunophenotype of aberrant IEL in RCDII patients.
Molecular immunology 2012;50(4):262-70.
2012: Menno van Lummel; Peter A van Veelen; Arnaud Zaldumbide; Antonis K Moustakas; George K Papadopoulos; Bart O Roep; Arnoud de Ru; Jan W Drijfhout; George M C Janssen; Frits Koning
Type 1 diabetes-associated HLA-DQ8 transdimer accommodates a unique peptide repertoire.
The Journal of biological chemistry 2012;287(12):9514-24.
2012: Elma M J Salentijn; Ingrid M van der Meer; Luud J W J Gilissen; Svetlana V Goryunova; Frits Koning; D Cristina Mitea; Ismael Padioleau; Marinus Smulders
Celiac disease T-cell epitopes from gamma-gliadins: immunoreactivity depends on the genome of origin, transcript frequency, and flanking protein variation.
BMC genomics 2012;13():277.
2012: Jorge R Mujico; Nermin Sajic; Lucia Streppel; Piet van Wichen; Ron Verheijen; Liesbeth Dekking; Jan W Drijfhout; Yvonne Kooy-Winkelaar; Frits Koning
Validation of a new enzyme-linked immunosorbent assay to detect the triggering proteins and peptides for celiac disease: interlaboratory study.
Journal of AOAC International 2012;95(1):206-15.
2011: Caroline E Hogen Esch; Frits Koning; M Luisa Mearin; Anja Roos; Friedo W Dekker; Frans M Helmerhorst; Mechteld J L Van Rijssen; Joachim J Schweizer
Screening for unrecognized coeliac disease in subfertile couples.
Scandinavian journal of gastroenterology 2011;46(12):1423-8.
2011: Yvonne Kooy-Winkelaar; M Luisa Mearin; Antonis K Moustakas; Chris J Mulder; George K Papadopoulos; Bart O Roep; Joachim Schweizer; Jeroen Van Bergen; Menno van Lummel; Jan Wouter Drijfhout; Frits Koning
Gluten-specific T cells cross-react between HLA-DQ8 and the HLA-DQ2α/DQ8β transdimer.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(10):5123-9.
2011: Jeroen Van Bergen; F H J Claas; Johan W de Fijter; Geert W Haasnoot; Frits Koning; Joke I Roodnat; Allan Thompson; I I N Doxiadis
KIR-ligand mismatches are associated with reduced long-term graft survival in HLA-compatible kidney transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2011;11(9):1959-64.
2011: Jennifer M-L Tjon; Yvonne M C Kooy-Winkelaar; Greetje J Tack; A Mieke Mommaas; Marco W J Schreurs; Marco W Schilham; Chris J Mulder; Jeroen Van Bergen; Frits Koning
DNAM-1 mediates epithelial cell-specific cytotoxicity of aberrant intraepithelial lymphocyte lines from refractory celiac disease type II patients.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(11):6304-12.
2010: Caroline Elisabeth Hogen Esch; Anna Rosén; Renata Auricchio; Jihane Romanos; Anna Chmielewska; Hein Putter; Anneli Ivarsson; Hania Szajewska; Frits Koning; Cisca Wijmenga; Riccardo Troncone; M Luisa Mearin
The PreventCD Study design: towards new strategies for the prevention of coeliac disease.
European journal of gastroenterology & hepatology 2010;22(12):1424-30.
2010: Marjolijn Duijvestein; Anne Christine W Vos; Helene Roelofs; Manon E Wildenberg; Barbara B Wendrich; Hein Verspaget; Engelina M C Kooy-Winkelaar; Frits Koning; Jaap-Jan Zwaginga; Herma H Fidder; Auke P Verhaar; Willem E Fibbe; Gijs R van den Brink; Daniel W Hommes
Autologous bone marrow-derived mesenchymal stromal cell treatment for refractory luminal Crohn's disease: results of a phase I study.
Gut 2010;59(12):1662-9.
2010: Jeroen Van Bergen; Frits Koning
The tortoise and the hare: slowly evolving T-cell responses take hastily evolving KIR.
Immunology 2010;131(3):301-9.
2010: Jennifer May-Ling Tjon; Jeroen Van Bergen; Frits Koning
Celiac disease: how complicated can it get?
Immunogenetics 2010;62(10):641-51.
2010: Cristina Mitea; Elma M J Salentijn; Peter van Veelen; Svetlana V Goryunova; Ingrid M van der Meer; Hetty C van den Broeck; Jorge R Mujico; Veronica Monserrat; Luud J W J Gilissen; Jan Wouter Drijfhout; Liesbeth Dekking; Frits Koning; Veronica Montserrat; Marinus Smulders
A universal approach to eliminate antigenic properties of alpha-gliadin peptides in celiac disease.
PloS one 2010;5(12):e15637.
2009: Willem Maat; Arno R van der Slik; Dirk H J Verhoeven; Behrooz Z Alizadeh; Long V Ly; Willem Verduijn; Gregorius P M Luyten; Arend Mulder; Thorbald van Hall; Frits Koning; Martine J Jager; Jeroen van Bergen
Evidence for natural killer cell-mediated protection from metastasis formation in uveal melanoma patients.
Investigative ophthalmology & visual science 2009;50(6):2888-95.
2009: Jeroen Van Bergen; Engelina M C Kooy-Winkelaar; Henrike van Dongen; Floris A van Gaalen; Allan Thompson; Tom W J Huizinga; Mariet C W Feltkamp; René E M Toes; Frits Koning
Functional killer Ig-like receptors on human memory CD4+ T cells specific for cytomegalovirus.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(7):4175-82.
2009: Jeroen Van Bergen; Allan Thompson; Christelle Retière; John Trowsdale; Frits Koning
Cutting edge: killer Ig-like receptors mediate "missing self" recognition in vivo.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(5):2569-72.
2009: Liesbeth Dekking; Frits Koning; Diane Hosek; Tara D Ondrak; Steve L Taylor; J W Schroeder; Marc Bauer
Intolerance of celiac disease patients to bovine milk is not due to the presence of T-cell stimulatory epitopes of gluten.
Nutrition (Burbank, Los Angeles County, Calif.) 2009;25(1):122-3.
2008: Jennifer M L Tjon; Wieke H M Verbeek; Yvonne M C Kooy-Winkelaar; Binh H Nguyen; Arno R van der Slik; Allan Thompson; Mirjam H M Heemskerk; Marco W J Schreurs; Liesbeth H A Dekking; Chris J Mulder; Jeroen Van Bergen; Frits Koning
Defective synthesis or association of T-cell receptor chains underlies loss of surface T-cell receptor-CD3 expression in enteropathy-associated T-cell lymphoma.
Blood 2008;112(13):5103-10.
2008: Cristina Mitea; Yvonne Kooy-Winkelaar; Peter van Veelen; Arnoud de Ru; Jan Wouter Drijfhout; Frits Koning; Liesbeth Dekking
Fine specificity of monoclonal antibodies against celiac disease-inducing peptides in the gluteome.
The American journal of clinical nutrition 2008;88(4):1057-66.
2008: Martina Wiesner; Dariusz Stepniak; Arnoud de Ru; Antonis K Moustakis; Jan Wouter Drijfhout; George K Papadopoulos; Peter van Veelen; Frits Koning
Dominance of an alternative CLIP sequence in the celiac disease associated HLA-DQ2 molecule.
Immunogenetics 2008;60(9):551-5.
2008: Erica G D Hopman; Mary E von Blomberg; Manou R Batstra; Hans Morreau; Friedo W Dekker; Frits Koning; Cor B H W Lamers; M Luisa Mearin
Gluten tolerance in adult patients with celiac disease 20 years after diagnosis?
European journal of gastroenterology & hepatology 2008;20(5):423-9.
2008: Frits Koning
Celiac disease: sandwiched between innate and adaptive immune responses induced by gluten.
Journal of pediatric gastroenterology and nutrition 2008;46 Suppl 1():E8-9.
2008: Dariusz Stepniak; Martina Wiesner; Arnoud de Ru; Antonis K Moustakas; Jan Wouter Drijfhout; George K Papadopoulos; Peter van Veelen; Frits Koning
Large-scale characterization of natural ligands explains the unique gluten-binding properties of HLA-DQ2.
Journal of immunology (Baltimore, Md. : 1950) 2008;180(5):3268-78.
2008: Erica Hopman; Liesbeth Dekking; Marie-Loes Blokland; Maud Wuisman; Walter Zuijderduin; Frits Koning; Joachim Schweizer
Tef in the diet of celiac patients in The Netherlands.
Scandinavian journal of gastroenterology 2008;43(3):277-82.
2008: Varsha V Kapoerchan; Martina Wiesner; Mark Overhand; Gijs A van der Marel; Frits Koning; Herman S Overkleeft
Design of azidoproline containing gluten peptides to suppress CD4+ T-cell responses associated with celiac disease.
Bioorganic & medicinal chemistry 2008;16(4):2053-62.
2008: C Mitea; R Havenaar; J Wouter Drijfhout; Luppo Edens; L Dekking; Frits Koning
Efficient degradation of gluten by a prolyl endoprotease in a gastrointestinal model: implications for coeliac disease.
Gut 2008;57(1):25-32.
2007: Frits Koning
A tertiary twist to the transglutaminase tale.
PLoS biology 2007;5(12):e337.
2006: Allan Thompson; Arno R van der Slik; Frits Koning; Jeroen Van Bergen
An improved RT-PCR method for the detection of killer-cell immunoglobulin-like receptor (KIR) transcripts.
Immunogenetics 2006;58(11):865-72.
2006: Dariusz Stepniak; Frits Koning
Enzymatic gluten detoxification: the proof of the pudding is in the eating!
Trends in biotechnology 2006;24(10):433-4.
2006: Dariusz Stepniak; Liesbeth Spaenij-Dekking; Cristina Mitea; Martine Moester; Arnoud de Ru; Renee Baak-Pablo; Peter van Veelen; Luppo Edens; Frits Koning
Highly efficient gluten degradation with a newly identified prolyl endoprotease: implications for celiac disease.
American journal of physiology. Gastrointestinal and liver physiology 2006;291(4):G621-9.
2006: Ellen A J Thomassen; E H A Dekking; A Thompson; Kees L M C Franken; O Sanal; Jan Pieter Abrahams; Maarten J D van Tol; Frits Koning
The impact of single amino acid substitutions in CD3gamma on the CD3epsilongamma interaction and T-cell receptor-CD3 complex formation.
Human immunology 2006;67(8):579-88.
2006: Dariusz Stepniak; Frits Koning
Celiac disease--sandwiched between innate and adaptive immunity.
Human immunology 2006;67(6):460-8.
2006: Alienke J Monsuur; Dariusz Stepniak; Begoña Diosdado; Martin C Wapenaar; M Luisa Mearin; Frits Koning; Cisca Wijmenga
Genetic and functional analysis of pyroglutamyl-peptidase I in coeliac disease.
European journal of gastroenterology & hepatology 2006;18(6):637-44.
2006: Thorbald van Hall; Elisabeth Z Wolpert; Peter van Veelen; Sandra Laban; Michael van der Veer; Marjet Roseboom; Sandra A Bres; Per Grufman; Arnoud de Ru; Hugo D Meiring; Annemieke de Jong; Kees L M C Franken; Antoinette Teixeira; Rob Valentijn; Jan Wouter Drijfhout; Frits Koning; Marcel Camps; Ferry Ossendorp; Klas Kärre; Hans-Gustaf Ljunggren; Cornelis J M Melief; Rienk Offringa
Selective cytotoxic T-lymphocyte targeting of tumor immune escape variants.
Nature medicine 2006;12(4):417-24.
2006: Teun W J M van Herpen; Svetlana V Goryunova; Johanna van der Schoot; Makedonka Mitreva; Elma Salentijn; Oscar Vorst; Martijn F Schenk; Peter van Veelen; Frits Koning; Loek J M van Soest; Ben Vosman; Dirk Bosch; Rob J Hamer; Luud J W J Gilissen; Marinus Smulders
Alpha-gliadin genes from the A, B, and D genomes of wheat contain different sets of celiac disease epitopes.
BMC genomics 2006;7():1.
2005: Arend Mulder; Chantal Eijsink; Michel Kester; Marry E I Franke; Marrie J Kardol; Mirjam H M Heemskerk; Cees van Kooten; Frank A W Verreck; Jan Wouter Drijfhout; Frits Koning; Ilias Doxiadis; Frans H J Claas
Impact of peptides on the recognition of HLA class I molecules by human HLA antibodies.
Journal of immunology (Baltimore, Md. : 1950) 2005;175(9):5950-7.
2005: Liesbeth Spaenij-Dekking; Yvonne Kooy-Winkelaar; Frits Koning
The Ethiopian cereal tef in celiac disease.
The New England journal of medicine 2005;353(16):1748-9.
2005: Frits Koning
Celiac disease: caught between a rock and a hard place.
Gastroenterology 2005;129(4):1294-301.
2005: Liesbeth Spaenij-Dekking; Yvonne Kooy-Winkelaar; Peter van Veelen; Jan Wouter Drijfhout; Harry Jonker; Loek van Soest; Marinus Smulders; Dirk Bosch; Luud J W J Gilissen; Frits Koning
Natural variation in toxicity of wheat: potential for selection of nontoxic varieties for celiac disease patients.
Gastroenterology 2005;129(3):797-806.
2005: Frits Koning; Luud J W J Gilissen; Cisca Wijmenga
Gluten: a two-edged sword. Immunopathogenesis of celiac disease.
Springer seminars in immunopathology 2005;27(2):217-32.
2005: Begoña Diosdado; Dariusz Stepniak; Alienke J Monsuur; Lude Franke; Martin C Wapenaar; M Luisa Mearin; Frits Koning; Cisca Wijmenga
No genetic association of the human prolyl endopeptidase gene in the Dutch celiac disease population.
American journal of physiology. Gastrointestinal and liver physiology 2005;289(3):G495-500.
2005: Frits Koning; Detlef Schuppan; Nadine Cerf-Bensussan; Ludvig M Sollid
Pathomechanisms in celiac disease.
Best practice & research. Clinical gastroenterology 2005;19(3):373-87.
2005: Dariusz Stepniak; L Willemijn Vader; Yvonne M C Kooy; Peter van Veelen; Antonis K Moustakas; Nikolaos A Papandreou; Elias Eliopoulos; Jan Wouter Drijfhout; George K Papadopoulos; Frits Koning
T-cell recognition of HLA-DQ2-bound gluten peptides can be influenced by an N-terminal proline at p-1.
Immunogenetics 2005;57(1-2):8-15.
2004: Jeroen Van Bergen; Allan Thompson; Arno R van der Slik; Tom H M Ottenhoff; Jacobijn Gussekloo; Frits Koning
Phenotypic and functional characterization of CD4 T cells expressing killer Ig-like receptors.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(11):6719-26.
2004: Helene Arentz-Hansen; Burkhard Fleckenstein; Øyvind Molberg; Helge Scott; Frits Koning; Günther Jung; Peter Roepstorff; Knut E A Lundin; Ludvig M Sollid
The molecular basis for oat intolerance in patients with celiac disease.
PLoS medicine 2004;1(1):e1.
2004: E H A Spaenij-Dekking; E M C Kooy-Winkelaar; Willem Nieuwenhuizen; Jan Wouter Drijfhout; Frits Koning
A novel and sensitive method for the detection of T cell stimulatory epitopes of alpha/beta- and gamma-gliadin.
Gut 2004;53(9):1267-73.
2004: Aura Muntasell; Montserrat Carrascal; Iñaki Alvarez; Laurence Serradell; Peter van Veelen; Frank A W Verreck; Frits Koning; Joaquin Abian; Dolores Jaraquemada
Dissection of the HLA-DR4 peptide repertoire in endocrine epithelial cells: strong influence of invariant chain and HLA-DM expression on the nature of ligands.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(2):1085-93.
2004: Pauline Verdijk; Peter van Veelen; Arnoud de Ru; Paul J Hensbergen; Kensaku Mizuno; Henk K Koerten; Frits Koning; Cornelis P Tensen; A Mieke Mommaas
Morphological changes during dendritic cell maturation correlate with cofilin activation and translocation to the cell membrane.
European journal of immunology 2004;34(1):156-64.
2003: E H A Spaenij-Dekking; J Van Delft; Els van der Meijden; HS Hiemstra; J H Frederik Falkenburg; Frits Koning; Jan Wouter Drijfhout; Johanna C Kluin-Nelemans
Synaptojanin 2 is recognized by HLA class II-restricted hairy cell leukemia-specific T cells.
Leukemia 2003;17(12):2467-73.
2003: Willemijn Vader; Dariusz Stepniak; Yvonne M C Kooy; Luisa Mearin; Allan Thompson; Jon van Rood; Liesbeth Spaenij; Frits Koning
The HLA-DQ2 gene dose effect in celiac disease is directly related to the magnitude and breadth of gluten-specific T cell responses.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(21):12390-5.
2003: L Willemijn Vader; Dariusz Stepniak; Evelien M Bunnik; Yvonne M C Kooy; Willeke de Haan; Jan Wouter Drijfhout; Peter van Veelen; Frits Koning
Characterization of cereal toxicity for celiac disease patients based on protein homology in grains.
Gastroenterology 2003;125(4):1105-13.
2003: Frits Koning
The molecular basis of celiac disease.
Journal of molecular recognition : JMR 2003;16(5):333-6.
2003: Katharina Gamerdinger; Corinne Moulon; David R Karp; Jeroen Van Bergen; Frits Koning; Doris Wild; Ulrike Pflugfelder; Hans Ulrich Weltzien
A new type of metal recognition by human T cells: contact residues for peptide-independent bridging of T cell receptor and major histocompatibility complex by nickel.
The Journal of experimental medicine 2003;197(10):1345-53.
2003: Frits Koning; Willemijn Vader
Gluten peptides and celiac disease.
Science (New York, N.Y.) 2003;299(5606):513-5; author reply 513-5.
2003: M Luisa Mearin; Frits Koning
Tissue transglutaminase: master regulator of celiac disease?
Journal of pediatric gastroenterology and nutrition 2003;36(1):9-11.
2003: Giuseppe Mazzarella; Maria Maglio; Francesco Paparo; Gerardo Nardone; Rosita Stefanile; Luigi Greco; Y van de Wal; Yvonne M C Kooy; Frits Koning; Salvatore Auricchio; Riccardo Troncone
An immunodominant DQ8 restricted gliadin peptide activates small intestinal immune response in in vitro cultured mucosa from HLA-DQ8 positive but not HLA-DQ8 negative coeliac patients.
Gut 2003;52(1):57-62.
2002: Aura Muntasell; Montserrat Carrascal; Laurence Serradell; Peter van Veelen Pv; Frank A W Verreck; Frits Koning; Graça Raposo; Joaquín Abián; Dolores Jaraquemada
HLA-DR4 molecules in neuroendocrine epithelial cells associate to a heterogeneous repertoire of cytoplasmic and surface self peptides.
Journal of immunology (Baltimore, Md. : 1950) 2002;169(9):5052-60.
2002: Frits Koning
Immunotherapy of celiac disease: fact or fallacy?
The Netherlands journal of medicine 2002;60(7):305-6.
2002: Willemijn Vader; Yvonne M C Kooy; Peter van Veelen; Arnoud de Ru; Diana Harris; Willemien Benckhuijsen; Amado Salvador Peña; Luisa Mearin; Jan Wouter Drijfhout; Frits Koning
The gluten response in children with celiac disease is directed toward multiple gliadin and glutenin peptides.
Gastroenterology 2002;122(7):1729-37.
2002: L Willemijn Vader; Arnoud de Ru; Yvonne van der Wal; Yvonne M C Kooy; Willemien Benckhuijsen; M Luisa Mearin; Jan Wouter Drijfhout; Peter van Veelen; Frits Koning
Specificity of tissue transglutaminase explains cereal toxicity in celiac disease.
The Journal of experimental medicine 2002;195(5):643-9.
2001: George K Papadopoulos; cisca wijmenga; Frits Koning
Interplay between genetics and the environment in the development of celiac disease: perspectives for a healthy life.
The Journal of clinical investigation 2001;108(9):1261-6.
2001: Mirjam H M Heemskerk; Roelof A de Paus; Ellie G A Lurvink; Frits Koning; Arend Mulder; Rein Willemze; Jon van Rood; J H Frederik Falkenburg
Dual HLA class I and class II restricted recognition of alloreactive T lymphocytes mediated by a single T cell receptor complex.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(12):6806-11.
2001: Jeroen Van Bergen; Yvonne M C Kooy; Frits Koning
CD4-independent T cells impair TCR triggering of CD4-dependent T cells: a putative mechanism for T cell affinity maturation.
European journal of immunology 2001;31(2):646-52.
2001: EA van Tienhoven; C T ten Brink; Jeroen Van Bergen; Frits Koning; Willem van Eden; Chris P M Broeren
Induction of antigen specific CD4+ T cell responses by invariant chain based DNA vaccines.
Vaccine 2001;19(11-12):1515-9.
2000: Jeroen Van Bergen; Marcel Camps; Rienk Offringa; Cornelis J M Melief; Ferry Ossendorp; Frits Koning
Superior tumor protection induced by a cellular vaccine carrying a tumor-specific T helper epitope by genetic exchange of the class II-associated invariant chain peptide.
Cancer research 2000;60(22):6427-33.
2000: Antonis K Moustakas; Y van de Wal; J Routsias; Yvonne M C Kooy; Peter van Veelen; Jan Wouter Drijfhout; Frits Koning; George K Papadopoulos
Structure of celiac disease-associated HLA-DQ8 and non-associated HLA-DQ9 alleles in complex with two disease-specific epitopes.
International immunology 2000;12(8):1157-66.
2000: Thorbald van Hall; Jeroen Van Bergen; Peter van Veelen; M Kraakman; Lukas Heukamp; Frits Koning; Cornelis J M Melief; Ferry Ossendorp; Rienk Offringa
Identification of a novel tumor-specific CTL epitope presented by RMA, EL-4, and MBL-2 lymphomas reveals their common origin.
Journal of immunology (Baltimore, Md. : 1950) 2000;165(2):869-77.
2000: Anita van den Biggelaar; Jane Grogan; Y Filié; R Jordens; Song Le; Frits Koning; Maria Yazdanbakhsh
Chronic schistosomiasis: dendritic cells generated from patients can overcome antigen-specific T cell hyporesponsiveness.
The Journal of infectious diseases 2000;182(1):260-5.
2000: Y van de Wal; Yvonne M C Kooy; Peter van Veelen; Willemijn Vader; Frits Koning; Amado Salvador Peña
Coeliac disease: it takes three to tango!
Gut 2000;46(5):734-7.
2000: Helene Arentz-Hansen; R Körner; Oyvind Molberg; Hanne Quarsten; Willemijn Vader; Yvonne M C Kooy; Knut E A Lundin; Frits Koning; Peter Roepstorff; Ludvig M Sollid; Stephen N McAdam
The intestinal T cell response to alpha-gliadin in adult celiac disease is focused on a single deamidated glutamine targeted by tissue transglutaminase.
The Journal of experimental medicine 2000;191(4):603-12.
2000: Y van de Wal; R Amons; Frits Koning
Characterization of HLA-DQ-Specific Peptide-Binding Motifs.
Methods in molecular medicine 2000;41():97-103.
2000: H S Hiemstra; Jan Wouter Drijfhout; Frits Koning
Synthetic Peptide libraries for T-cell epitope identification.
Methods in molecular medicine 2000;41():89-96.
2000: Peter van Veelen; Jan Wouter Drijfhout; Frits Koning
Structure elucidation of gluten-derived peptides by tandem mass spectrometry.
Methods in molecular medicine 2000;41():75-88.
1999: Jeroen Van Bergen; Ferry Ossendorp; R Jordens; A Mieke Mommaas; Jan Wouter Drijfhout; Frits Koning
Get into the groove! Targeting antigens to MHC class II.
Immunological reviews 1999;172():87-96.
1999: R Jordens; A Thompson; R Amons; Frits Koning
Human dendritic cells shed a functional, soluble form of the mannose receptor.
International immunology 1999;11(11):1775-80.
1999: Y van de Wal; Yvonne M C Kooy; Peter van Veelen; Willemijn Vader; S A August; Jan Wouter Drijfhout; Amado Salvador Peña; Frits Koning
Glutenin is involved in the gluten-driven mucosal T cell response.
European journal of immunology 1999;29(10):3133-9.
1999: H S de Koster; Corine Vermeulen; HS Hiemstra; R Amons; Jan Wouter Drijfhout; Frits Koning
Definition of agonists and design of antagonists for alloreactive T cell clones using synthetic peptide libraries.
International immunology 1999;11(4):585-91.
1999: A Mieke Mommaas; Aat A Mulder; R Jordens; Coby J Out; MC Tan; P Cresswell; P M Kluin; Frits Koning
Human epidermal Langerhans cells lack functional mannose receptors and a fully developed endosomal/lysosomal compartment for loading of HLA class II molecules.
European journal of immunology 1999;29(2):571-80.
1998: Monique M ten Dam; Y van de Wal; M Luisa Mearin; Yvonne M C Kooy; Amado Salvador Peña; Jan Wouter Drijfhout; Frits Koning; Maarten J D van Tol
Anti-alpha-gliadin antibodies (AGA) in the serum of coeliac children and controls recognize an identical collection of linear epitopes of alpha-gliadin.
Clinical and experimental immunology 1998;114(2):189-95.
1998: M C Agnes; A Tan; R Jordens; Annemieke Geluk; B O Roep; Tom H M Ottenhoff; Jan Wouter Drijfhout; Frits Koning
Strongly increased efficiency of altered peptide ligands by mannosylation.
International immunology 1998;10(9):1299-304.
1998: Jeroen Van Bergen; Frits Koning
Altered peptide ligands and wild-type peptide induce indistinguishable responses of a human Th0 clone.
European journal of immunology 1998;28(9):2801-8.
1998: Y van de Wal; Yvonne M C Kooy; Peter van Veelen; Amado Salvador Peña; Luisa Mearin; Oyvind Molberg; Knut E A Lundin; Ludvig M Sollid; Tuna Mutis; Willemien Benckhuijsen; Jan Wouter Drijfhout; Frits Koning
Small intestinal T cells of celiac disease patients recognize a natural pepsin fragment of gliadin.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(17):10050-4.
1998: Y van de Wal; Yvonne M C Kooy; Peter van Veelen; Amado Salvador Peña; Luisa Mearin; G Papadopoulos; Frits Koning
Selective deamidation by tissue transglutaminase strongly enhances gliadin-specific T cell reactivity.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1585-8.
1998: C Terreaux; TB Walk; Y van de Wal; Frits Koning; Günther Jung; Burkhard Fleckenstein
Increased HLA-DQ2-affinity of a synthetic gliadin peptide by acid-induced deamidation of glutamine residues.
Bioorganic & medicinal chemistry letters 1998;8(15):2039-44.
1998: H S de Koster; Corine Vermeulen; Frits Koning
The majority of HLA-DR3 alloreactive T cells is peptide specific, but does not recognize known DR3-bound sequences.
Tissue antigens 1998;51(1):88-95.
1997: MC Tan; A Mieke Mommaas; Jan Wouter Drijfhout; R Jordens; Jos J M Onderwater; Desiree Verwoerd; Aat A Mulder; A N van der Heiden; D Scheidegger; Lauran Oomen; Tom H M Ottenhoff; A Tulp; Jacques Neefjes; Frits Koning
Mannose receptor-mediated uptake of antigens strongly enhances HLA class II-restricted antigen presentation by cultured dendritic cells.
European journal of immunology 1997;27(9):2426-35.
1997: Jeroen Van Bergen; Stephen P Schoenberger; Frank A W Verreck; R Amons; Rienk Offringa; Frits Koning
Efficient loading of HLA-DR with a T helper epitope by genetic exchange of CLIP.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(14):7499-502.
1997: Frits Koning
Enhancement of HLA class II restricted antigen presentation by mannose-receptor-mediated uptake.
Biochemical Society transactions 1997;25(2):664-5.
1997: Frits Koning
Celiac disease and malignancy: an immunological basis?
Journal of pediatric gastroenterology and nutrition 1997;24(5):S18-9.
1997: Y van de Wal; Yvonne M C Kooy; Jan Wouter Drijfhout; R Amons; George K Papadopoulos; Frits Koning
Unique peptide binding characteristics of the disease-associated DQ(alpha 1*0501, beta 1*0201) vs the non-disease-associated DQ(alpha 1*0201, beta 1*0202) molecule.
Immunogenetics 1997;46(6):484-92.
1997: MC Tan; A Mieke Mommaas; Jan Wouter Drijfhout; R Jordens; Jos J M Onderwater; Desiree Verwoerd; Aat A Mulder; A N van der Heiden; Tom H M Ottenhoff; M Cella; A Tulp; Jacques Neefjes; Frits Koning
Mannose receptor mediated uptake of antigens strongly enhances HLA-class II restricted antigen presentation by cultured dendritic cells.
Advances in experimental medicine and biology 1997;417():171-4.
1996: T J Nieland; M C Tan; M Monne-van Muijen; Frits Koning; Ada M Kruisbeek; G M van Bleek
Isolation of an immunodominant viral peptide that is endogenously bound to the stress protein GP96/GRP94.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(12):6135-9.
1996: F A Verreck; Corine Vermeulen; A V Poel; P Jorritsma; R Amons; J E Coligan; Jan Wouter Drijfhout; Frits Koning
The generation of SDS-stable HLA DR dimers is independent of efficient peptide binding.
International immunology 1996;8(3):397-404.
1996: Y van de Wal; Yvonne M C Kooy; Jan Wouter Drijfhout; R Amons; Frits Koning
Peptide binding characteristics of the coeliac disease-associated DQ(alpha1*0501, beta1*0201) molecule.
Immunogenetics 1996;44(4):246-53.
1995: D L Orsini; Yvonne M C Kooy; M A Van der Tol; L Struyk; P Van den Elsen; Frits Koning
T-cell receptor usage of interleukin-2-responsive peripheral gamma delta T cells.
Immunology 1995;86(3):385-91.
1995: K Söderström; Anders Bucht; Eva Halapi; C Lundqvist; A Grönberg; E Nilsson; D L Orsini; Y van de Wal; Frits Koning; Marie-Louise Hammarström
Human gamma delta T-cells in the epithelium of the gut and in the inflamed synovial tissue preferentially express the V gamma 8 T-cell receptor chain.
Annals of the New York Academy of Sciences 1995;756():406-9.
1995: Joke M M den Haan; N E Sherman; Els Blokland; E Huczko; Frits Koning; Jan Wouter Drijfhout; JC Skipper; Jeffrey Shabanowitz; Donald F Hunt; Victor H Engelhard
Identification of a graft versus host disease-associated human minor histocompatibility antigen.
Science (New York, N.Y.) 1995;268(5216):1476-80.
1995: D L Orsini; Yvonne M C Kooy; L Struyk; F Ossendorp; P Van den Elsen; Frits Koning
Identification of two distinct function gamma delta TCR complexes on the surface of a human T cell clone.
Scandinavian journal of immunology 1995;41(5):499-503.
1995: F A Verreck; Diënne G Elferink; Corine Vermeulen; R Amons; F Breedveld; René R P De Vries; Frits Koning
DR4Dw4/DR53 molecules contain a peptide from the autoantigen calreticulin.
Tissue antigens 1995;45(4):270-5.
1995: A Mieke Mommaas; Aat A Mulder; C J Out; Giampiero Girolomoni; Henk K Koerten; Bert-Jan Vermeer; Frits Koning
Distribution of HLA class II molecules in epidermal Langerhans cells in situ.
European journal of immunology 1995;25(2):520-5.
1994: M Mommaas; A Mulder; Bert-Jan Vermeer; Frits Koning
Functional human epidermal Langerhans cells that lack Birbeck granules.
The Journal of investigative dermatology 1994;103(6):807-10.
1994: D L Orsini; M van Gils; Yvonne M C Kooy; L Struyk; G Klein; P van den Elsen; Frits Koning
Functional and molecular characterization of B cell-responsive V delta 1+ gamma delta T cells.
European journal of immunology 1994;24(12):3199-204.
1994: K Söderström; Anders Bucht; Eva Halapi; C Lundqvist; A Grönberg; E Nilsson; D L Orsini; Y van de Wal; Frits Koning; Marie-Louise Hammarström
High expression of V gamma 8 is a shared feature of human gamma delta T cells in the epithelium of the gut and in the inflamed synovial tissue.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(12):6017-27.
1994: F A Verreck; A van de Poel; A Termijtelen; R Amons; Jan Wouter Drijfhout; Frits Koning
Identification of an HLA-DQ2 peptide binding motif and HLA-DPw3-bound self-peptide by pool sequencing.
European journal of immunology 1994;24(2):375-9.
1993: D L Orsini; P C Res; J M Van Laar; L M Muller; A E Soprano; Yvonne M C Kooy; Paul P Tak; Frits Koning
A subset of V delta 1+ T cells proliferates in response to Epstein-Barr virus-transformed B cell lines in vitro.
Scandinavian journal of immunology 1993;38(4):335-40.
1993: C Rust; D Orsini; Yvonne M C Kooy; Frits Koning
Reactivity of human gamma delta T cells to staphylococcal enterotoxins: a restricted reaction pattern mediated by two distinct recognition pathways.
Scandinavian journal of immunology 1993;38(1):89-94.
1993: F A Verreck; A Termijtelen; Frits Koning
HLA-DR beta chain residue 86 controls DR alpha beta dimer stability.
European journal of immunology 1993;23(6):1346-50.
1993: M de Bueger; F Verreck; Els Blokland; Jan Wouter Drijfhout; R Amons; Frits Koning; Els Goulmy
Isolation of an HLA-A2.1 extracted human minor histocompatibility peptide.
European journal of immunology 1993;23(3):614-8.
1993: C J Rust; Frits Koning
Gamma delta T cell reactivity towards bacterial superantigens.
Seminars in immunology 1993;5(1):41-6.
1992: Frits Koning; C Rust
Staphylococcal enterotoxin-mediated human T-T cell interactions.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(1):317-22.
1992: A Mieke Mommaas; M C Wijsman; Aat A Mulder; MC Van Praag; Bert-Jan Vermeer; Frits Koning
HLA class II expression on human epidermal Langerhans cells in situ: upregulation during the elicitation of allergic contact dermatitis.
Human immunology 1992;34(2):99-106.
1992: C Rust; Yvonne M C Kooy; Amado Salvador Peña; M Luisa Mearin; Philip M Kluin; Frits Koning
Phenotypical and functional characterization of small intestinal TcR gamma delta + T cells in coeliac disease.
Scandinavian journal of immunology 1992;35(4):459-68.
1991: D van der Harst; Anneke Brand; S A P van Luxemburg-Heijs; Y M Kooij-Winkelaar; F E Zwaan; Frits Koning
Selective outgrowth of CD45RO+ V gamma 9+/V delta 2+ T-cell receptor gamma/delta T cells early after bone marrow transplantation.
Blood 1991;78(7):1875-81.
1991: Philip M Kluin; C J Rust; M Luisa Mearin; A S Peña; Frits Koning
TCR gamma delta cells: antigen-driven expansion of distinct subsets based on localization and antigen specificity.
Immunologic research 1991;10(3-4):313-20.
1990: C Rust; Amado Salvador Peña; Philip M Kluin; Frits Koning
Gamma delta T cells in coeliac disease.
Research in immunology 1990;141(7):668-71.
1990: J Van Neerven; J E Coligan; Frits Koning
Structural comparison of alpha/beta and gamma/delta T cell receptor-CD3 complexes reveals identical subunit interactions but distinct cross-linking patterns of T cell receptor chains.
European journal of immunology 1990;20(9):2105-11.
1990: C J Rust; F Verreck; H Vietor; Frits Koning
Specific recognition of staphylococcal enterotoxin A by human T cells bearing receptors with the V gamma 9 region.
Nature 1990;346(6284):572-4.
1990: B A Vandekerckhove; G Datema; Frits Koning; Els Goulmy; Guido G Persijn; Jon van Rood; Frans H J Claas; J E de Vries
Analysis of the donor-specific cytotoxic T-cell repertoire in a patient with a long-term surviving kidney allograft.
Transplantation proceedings 1990;22(4):1871-2.
1990: S G Li; Tom H M Ottenhoff; P Van den Elsen; Frits Koning; L Zhang; T Mak; René R P De Vries
Human suppressor T cell clones lack CD28.
European journal of immunology 1990;20(6):1281-8.
1990: B A Vandekerckhove; G Datema; Frits Koning; Els Goulmy; Guido G Persijn; Jon van Rood; Frans H J Claas; J E De Vries
Analysis of the donor-specific cytotoxic T lymphocyte repertoire in a patient with a long term surviving allograft. Frequency, specificity, and phenotype of donor-reactive T cell receptor (TCR)-alpha beta+ and TCR-gamma delta+ clones.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(4):1288-94.
1990: H Vietor; Frits Koning
Gamma delta T-cell receptor repertoire in human peripheral blood and thymus.
Immunogenetics 1990;31(5-6):340-6.
1990: N van der Stoep; R de Krijger; J Bruining; Frits Koning; P van den Elsen
Analysis of early fetal T-cell receptor delta chain in humans.
Immunogenetics 1990;32(5):331-6.
1989: Frits Koning; M Knot; F Wassenaar; P Van den Elsen
Phenotypical heterogeneity among human T cell receptor gamma/delta-expressing clones derived from peripheral blood.
European journal of immunology 1989;19(11):2099-105.
1989: A Termijtelen; P van den Elsen; Frits Koning; S de Koster; W Schroeijers; B Vanderkerckhove
A novel T-cell-defined HLA-DR polymorphism not predicted from the linear amino acid sequence.
Human immunology 1989;26(1):47-58.
1988: Bert-Jan Vermeer; A Mieke Mommaas; M C Wijsman; Frits Koning; Frans H J Claas
Ultrastructural localization of HLA-DR and HLA-DQ molecules in Langerhans cells and B cells: an immunoelectronmicroscopic study.
Regional immunology 1988;1(2):85-91.
1985: Tom H M Ottenhoff; Diënne G Elferink; A Termijtelen; Frits Koning; René R P De Vries
HLA class II restriction repertoire of antigen-specific T cells. II. Evidence for a new restriction determinant associated with DRw52 and LB-Q1.
Human immunology 1985;13(2):117-23.