Takao Konoshima

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Iranshahi Mehrdad; Sahebkar Amirhossein; Takasaki Midori; Konoshima Takao; Tokuda Harukuni
Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo.
Takasaki Midori; Konoshima Takao; Kozuka Mutsuo; Tokuda Harukuni; Takayasu Junko; Nishino Hoyoku; Miyakoshi Masazumi; Mizutani Kenji; Lee Kuo-Hsiung
Cancer preventive agents. Part 8: Chemopreventive effects of stevioside and related compounds.
Koyama Junko; Morita Izumi; Kobayashi Norihiro; Konoshima Takao; Takasaki Midori; Osakai Toshiyuki; Tokuda Harukuni
Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids.

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2009: Iranshahi Mehrdad; Sahebkar Amirhossein; Takasaki Midori; Konoshima Takao; Tokuda Harukuni
Cancer chemopreventive activity of the prenylated coumarin, umbelliprenin, in vivo.
European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) 2009;18(5):412-5.
2009: Takasaki Midori; Konoshima Takao; Kozuka Mutsuo; Tokuda Harukuni; Takayasu Junko; Nishino Hoyoku; Miyakoshi Masazumi; Mizutani Kenji; Lee Kuo-Hsiung
Cancer preventive agents. Part 8: Chemopreventive effects of stevioside and related compounds.
Bioorganic & medicinal chemistry 2009;17(2):600-5.
2008: Koyama Junko; Morita Izumi; Kobayashi Norihiro; Konoshima Takao; Takasaki Midori; Osakai Toshiyuki; Tokuda Harukuni
Correlation between oxidation potentials and inhibitory effects on Epstein-Barr virus activation of flavonoids.
Cancer letters 2008;263(1):61-6.
2007: Ito Hideyuki; Miyake Masateru; Nishitani Eisei; Miyashita Kyoko; Yoshimura Morio; Yoshida Takashi; Takasaki Midori; Konoshima Takao; Kozuka Mutsuo; Hatano Tsutomu
Cowaniin, a C-glucosidic ellagitannin dimer linked through catechin from Cowania mexicana.
Chemical & pharmaceutical bulletin 2007;55(3):492-4.
2006: Ishihara Keiichi; Yamagishi Nobuyuki; Saito Youhei; Takasaki Midori; Konoshima Takao; Hatayama Takumi
Arctigenin from Fructus Arctii is a novel suppressor of heat shock response in mammalian cells.
Cell stress & chaperones 2006;11(2):154-61.
2005: Colombo Diego; Franchini Laura; Toma Lucio; Ronchetti Fiamma; Nakabe Nami; Konoshima Takako; Nishino Hoyoku; Tokuda Harukuni
Anti-tumor-promoting activity of simple models of galactoglycerolipids with branched and unsaturated acyl chains.
European journal of medicinal chemistry 2005;40(1):69-74.
2005: Konishi Tenji; Konoshima Takao; Daikonya Akihiro; Kitanaka Susumu
Neolignans from Piper futokadsura and their inhibition of nitric oxide production.
Chemical & pharmaceutical bulletin 2005;53(1):121-4.
2004: Azuine Magnus A; Tokuda Harukuni; Takayasu Junko; Enjyo Fumio; Mukainaka Teruo; Konoshima Takao; Nishino Hoyoku; Kapadia Govind J
Cancer chemopreventive effect of phenothiazines and related tri-heterocyclic analogues in the 12-O-tetradecanoylphorbol-13-acetate promoted Epstein-Barr virus early antigen activation and the mouse skin two-stage carcinogenesis models.
Pharmacological research : the official journal of the Italian Pharmacological Society 2004;49(2):161-9.
2003: Konishi Tenji; Yamazoe Kiyonori; Konoshima Takao; Fujiwara Yasuhiro
Seco-labdane type diterpenes from Excoecaria agallocha.
Phytochemistry 2003;64(4):835-40.
2003: Konishi Tenji; Yamazoe Kiyonori; Kanzato Masahiro; Konoshima Takao; Fujiwara Yasuhiro
Three diterpenoids (excoecarins V1-V3) and a flavanone glycoside from the fresh stem of Excoecaria agallocha.
Chemical & pharmaceutical bulletin 2003;51(10):1142-6.
2003: Jiménez Ignacio A; Bazzocchi Isabel L; Núñez Marvin J; Mukainaka Teruo; Tokuda Harukuni; Nishino Hoyoku; Konoshima Takao; Ravelo Angel G
Absolute configuration of sesquiterpenes from Crossopetalum tonduzii and their inhibitory effects on Epstein-Barr virus early antigen activation in Raji cells.
Journal of natural products 2003;66(8):1047-50.
2003: Takasaki Midori; Konoshima Takao; Murata Yuji; Sugiura Masaki; Nishino Hoyoku; Tokuda Harukuni; Matsumoto Kazuhiro; Kasai Ryoji; Yamasaki Kazuo
Anticarcinogenic activity of natural sweeteners, cucurbitane glycosides, from Momordica grosvenori.
Cancer letters 2003;198(1):37-42.
2003: Kapadia Govind J; Azuine Magnus A; Sridhar Rajagopalan; Okuda Yoko; Tsuruta Atsushi; Ichiishi Eiichiro; Mukainake Teruo; Takasaki Midori; Konoshima Takao; Nishino Hoyoku; Tokuda Harukuni
Chemoprevention of DMBA-induced UV-B promoted, NOR-1-induced TPA promoted skin carcinogenesis, and DEN-induced phenobarbital promoted liver tumors in mice by extract of beetroot.
Pharmacological research : the official journal of the Italian Pharmacological Society 2003;47(2):141-8.
2003: Konishi Tenji; Yamazoe Kiyonori; Konoshima Takao; Maoka Takashi; Fujiwara Yasuhiro; Miyahara Kazumoto
New bis-secolabdane diterpenoids from Excoecaria agallocha.
Journal of natural products 2003;66(1):108-11.
2002: Katsuyama Isamu; Fahmy Hesham; Zjawiony Jordan K; Khalifa Sherief I; Kilada Raouf W; Konoshima Takao; Takasaki Midori; Tokuda Harakuni
Semisynthesis of new sarcophine derivatives with chemopreventive activity.
Journal of natural products 2002;65(12):1809-14.
2002: Konishi Tenji; Shimada Yasuo; Nagao Tsuneatsu; Okabe Hikaru; Konoshima Takao
Antiproliferative sesquiterpene lactones from the roots of Inula helenium.
Biological & pharmaceutical bulletin 2002;25(10):1370-2.
2002: Kapadia Govind J; Azuine Magnus A; Tokuda Harukuni; Takasaki Midori; Mukainaka Teruo; Konoshima Takao; Nishino Hoyoku
Chemopreventive effect of resveratrol, sesamol, sesame oil and sunflower oil in the Epstein-Barr virus early antigen activation assay and the mouse skin two-stage carcinogenesis.
Pharmacological research : the official journal of the Italian Pharmacological Society 2002;45(6):499-505.
2002: Konishi Tenji; Konoshima Takao; Shimada Yasuo; Kiyosawa Shiu
Six new 2-(2-phenylethyl)chromones from Agarwood.
Chemical & pharmaceutical bulletin 2002;50(3):419-22.
2002: Chakraborty Asima; Brantner Adelheid; Mukainaka Teruo; Nobukuni Yoshitoshi; Kuchide Masashi; Konoshima Takao; Tokuda Harukuni; Nishino Hoyoku
Cancer chemopreventive activity of Achyranthes aspera leaves on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2002;177(1):1-5.
2001: Konoshima T; Konishi T; Takasaki M; Yamazoe K; Tokuda H
Anti-tumor-promoting activity of the diterpene from Excoecaria agallocha. II.
Biological & pharmaceutical bulletin 2001;24(12):1440-2.
2001: Nishino H; Tokuda H; Ii T; Takemura M; Kuchide M; Kanazawa M; Mou X Y; Bu P; Takayasu J; Onozuka M; Masuda M; Satomi Y; Konoshima T; Kishi N; Baba M; Okada Y; Okuyama T
Cancer chemoprevention by ginseng in mouse liver and other organs.
Journal of Korean medical science 2001;16 Suppl():S66-9.
2001: Takasaki M; Kuroki S; Kozuka M; Konoshima T
New phenylpropanoid esters of sucrose from Polygonum lapathifolium.
Journal of natural products 2001;64(10):1305-8.
2001: Konishi T; Fujiwara Y; Konoshima T; Kiyosawa S; Nishi M; Miyahara K
Steroidal saponins from Hemerocallis fulva var. kwanso.
Chemical & pharmaceutical bulletin 2001;49(3):318-20.
2000: Kapadia G J; Azuine M A; Takayasu J; Konoshima T; Takasaki M; Nishino H; Tokuda H
Inhibition of epstein-barr virus early antigen activation promoted by 12-O-tetradecanoylphorbol-13-acetate by the non-steroidal anti-inflammatory drugs.
Cancer letters 2000;161(2):221-9.
2000: Ishida J; Kozuka M; Wang H; Konoshima T; Tokuda H; Okuda M; Yang Mou X; Nishino H; Sakurai N; Lee K H; Nagai M
Antitumor-promoting effects of cyclic diarylheptanoids on Epstein-Barr virus activation and two-stage mouse skin carcinogenesis.
Cancer letters 2000;159(2):135-40.
2000: Ito H; Nishitani E; Konoshima T; Takasaki M; Kozuka M; Yoshida T
Flavonoid and benzophenone glycosides from Coleogyne ramosissima.
Phytochemistry 2000;54(7):695-700.
2000: González A G; Tincusi B M; Bazzocchi I L; Tokuda H; Nishino H; Konoshima T; Jiménez I A; Ravelo A G
Anti-tumor promoting effects of sesquiterpenes from Maytenus cuzcoina (Celastraceae).
Bioorganic & medicinal chemistry 2000;8(7):1773-8.
2000: Konishi T; Konoshima T; Fujiwara Y; Kiyosawa S
Excoecarins D, E, and K, from excoecaria agallocha.
Journal of natural products 2000;63(3):344-6.
1999: Konoshima T; Takasaki M; Ichiishi E; Murakami T; Tokuda H; Nishino H; Duc N M; Kasai R; Yamasaki K
Cancer chemopreventive activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis.
Cancer letters 1999;147(1-2):11-6.
1999: Konoshima T; Takasaki M; Tokuda H
Anti-carcinogenic activity of the roots of Panax notoginseng. II.
Biological & pharmaceutical bulletin 1999;22(10):1150-2.
1999: Ito H; Miyake M; Nishitani E; Mori K; Hatano T; Okuda T; Konoshima T; Takasaki M; Kozuka M; Mukainaka T; Tokuda H; Nishino H; Yoshida T
Anti-tumor promoting activity of polyphenols from Cowania mexicana and Coleogyne ramosissima.
Cancer letters 1999;143(1):5-13.
1999: Colombo D; Compostella F; Ronchetti F; Scala A; Toma L; Mukainaka T; Nagatsu A; Konoshima T; Tokuda H; Nishino H
Inhibitory effects of monoacylated 2-O-beta-galactosylglycerols on Epstein-Barr virus activation: the significant role of the hexanoyl chain.
Cancer letters 1999;143(1):1-4.
1999: Takasaki M; Tokuda H; Nishino H; Konoshima T
Cancer chemopreventive agents (antitumor-promoters) from Ajuga decumbens.
Journal of natural products 1999;62(7):972-5.
1999: Takasaki M; Konoshima T; Tokuda H; Masuda K; Arai Y; Shiojima K; Ageta H
Anti-carcinogenic activity of Taraxacum plant. II.
Biological & pharmaceutical bulletin 1999;22(6):606-10.
1999: Takasaki M; Konoshima T; Tokuda H; Masuda K; Arai Y; Shiojima K; Ageta H
Anti-carcinogenic activity of Taraxacum plant. I.
Biological & pharmaceutical bulletin 1999;22(6):602-5.
1998: Motohashi N; Yamagami C; Tokuda H; Konoshima T; Okuda Y; Okuda M; Mukainaka T; Nishino H; Saito Y
Inhibitory effects of dehydrozingerone and related compounds on 12-O-tetradecanoylphorbol-13-acetate induced Epstein-Barr virus early antigen activation.
Cancer letters 1998;134(1):37-42.
1998: Konishi T; Takasaki M; Tokuda H; Kiyosawa S; Konoshima T
Anti-tumor-promoting activity of diterpenes from Excoecaria agallocha.
Biological & pharmaceutical bulletin 1998;21(9):993-6.
1998: Konoshima T; Takasaki M; Tokuda H; Nishino H; Duc N M; Kasai R; Yamasaki K
Anti-tumor-promoting activity of majonoside-R2 from Vietnamese ginseng, Panax vietnamensis Ha et Grushv. (I).
Biological & pharmaceutical bulletin 1998;21(8):834-8.
1998: Kapadia G J; Tokuda H; Sridhar R; Balasubramanian V; Takayasu J; Bu P; Enjo F; Takasaki M; Konoshima T; Nishino H
Cancer chemopreventive activity of synthetic colorants used in foods, pharmaceuticals and cosmetic preparations.
Cancer letters 1998;129(1):87-95.
1997: Konoshima T; Takasaki M; Kozuka M; Tokuda H; Nishino H; Matsuda E; Nagai M
Anti-tumor promoting activities of isoflavonoids from Wistaria brachybotrys.
Biological & pharmaceutical bulletin 1997;20(8):865-8.
1997: Takasaki M; Konoshima T; Yasuda I; Hamano T; Tokuda H
Inhibitory effects of shouseiryu-to on two-stage carcinogenesis. II. Anti-tumor-promoting activities of lignans from Asiasarum heterotropoides var. mandshuricum.
Biological & pharmaceutical bulletin 1997;20(7):776-80.
1997: Kapadia G J; Balasubramanian V; Tokuda H; Konoshima T; Takasaki M; Koyama J; Tagahaya K; Nishino H
Anti-tumor promoting effects of naphthoquinone derivatives on short term Epstein-Barr early antigen activation assay and in mouse skin carcinogenesis.
Cancer letters 1997;113(1-2):47-53.
1996: Kapadia G J; Tokuda H; Konoshima T; Takasaki M; Takayasu J; Nishino H
Anti-tumor promoting activity of Dryopteris phlorophenone derivatives.
Cancer letters 1996;105(2):161-5.
1996: Konoshima T; Takasaki M; Tokuda H; Masuda K; Arai Y; Shiojima K; Ageta H
Anti-tumor-promoting activities of triterpenoids from ferns. I.
Biological & pharmaceutical bulletin 1996;19(7):962-5.
1996: Konishi T; Nishio T; Kiyosawa S; Fujiwara Y; Konoshima T
[The constituents of Taxillus kaempferi and the host, Pinus thunbergii. I. Catechins and flavones of Taxillus kaempferi]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1996;116(2):148-57.
1996: Kapadia G J; Tokuda H; Konoshima T; Nishino H
Chemoprevention of lung and skin cancer by Beta vulgaris (beet) root extract.
Cancer letters 1996;100(1-2):211-4.
1996: Konoshima T
Anti-tumor-promoting activities or triterpenoid glycosides; cancer chemoprevention by saponins.
Advances in experimental medicine and biology 1996;404():87-100.
1995: Konoshima T; Yasuda I; Kashiwada Y; Cosentino L M; Lee K H
Anti-AIDS agents, 21. Triterpenoid saponins as anti-HIV principles from fruits of Gleditsia japonica and Gymnocladus chinensis, and a structure-activity correlation.
Journal of natural products 1995;58(9):1372-7.
1995: Shi Q; Chen K; Li L; Chang J J; Autry C; Kozuka M; Konoshima T; Estes J R; Lin C M; Hamel E
Antitumor agents, 154. Cytotoxic and antimitotic flavonols from Polanisia dodecandra.
Journal of natural products 1995;58(4):475-82.
1995: Takasaki M; Konoshima T; Kozuka M; Tokuda H
Anti-tumor-promoting activities of euglobals from Eucalyptus plants.
Biological & pharmaceutical bulletin 1995;18(3):435-8.
1995: Takasaki M; Konoshima T; Kozuka M; Yoneyama K; Yoshida S; Tokuda H; Nishino H; Iwashima A
Inhibitors of skin-tumor promotion. XIII. Inhibitory effects of euglobals and their related compounds on Epstein-Barr virus activation and on two-stage carcinogenesis of mouse skin tumors. (2).
Biological & pharmaceutical bulletin 1995;18(2):288-94.
1995: Konoshima T; Takasaki M; Kozuka M; Nagao T; Okabe H; Irino N; Nakasumi T; Tokuda H; Nishino H
Inhibitory effects of cucurbitane triterpenoids on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumor. II.
Biological & pharmaceutical bulletin 1995;18(2):284-7.
1994: Takasaki M; Konoshima T; Kozuka M; Haruna M; Ito K; Crow W D; Paton D M
Euglobal-In-1, a new euglobal from Eucalyptus incrassata.
Chemical & pharmaceutical bulletin 1994;42(10):2113-6.
1994: Konoshima T; Takasaki M; Tatsumoto T; Kozuka M; Kasai R; Tanaka O; Nie R L; Tokuda H; Nishino H; Iwashima A
Inhibitory effects of cucurbitane triterpenoids on Epstein-Barr virus activation and two-stage carcinogenesis of skin tumors.
Biological & pharmaceutical bulletin 1994;17(5):668-71.
1994: Konoshima T; Takasaki M; Kozuka M; Tokuda H
[Anti-tumor promoting activities of kampo prescriptions. II. Inhibitory effects of souseiryu-to on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1994;114(4):248-56.
1993: Inada A; Nakanishi T; Konoshima T; Kozuka M; Tokuda H; Nishino H; Iwashima A
Anti-tumor promoting activities of natural products. II. Inhibitory effects of digitoxin on two-stage carcinogenesis of mouse skin tumors and mouse pulmonary tumors.
Biological & pharmaceutical bulletin 1993;16(9):930-1.
1993: Konoshima T; Takasaki M; Kozuka M; Haruna M; Ito K; Estes J R; Lee K H
Constituents of rosaceous plants. I. Structure of new triterpenoids from Cowania mexicana.
Chemical & pharmaceutical bulletin 1993;41(9):1612-5.
1993: Konoshima T; Terada H; Kokumai M; Kozuka M; Tokuda H; Estes J R; Li L; Wang H K; Lee K H
Studies on inhibitors of skin tumor promotion, XII. Rotenoids from Amorpha fruticosa.
Journal of natural products 1993;56(6):843-8.
1993: Li L; Wang H K; Chang J J; McPhail A T; McPhail D R; Terada H; Konoshima T; Kokumai M; Kozuka M; Estes J R
Antitumor agents, 138. Rotenoids and isoflavones as cytotoxic constitutents from Amorpha fruticosa.
Journal of natural products 1993;56(5):690-8.
1992: Konoshima T; Kokumai M; Kozuka M; Tokuda H; Nishino H; Iwashima A
Anti-tumor-promoting activities of afromosin and soyasaponin I isolated from Wistaria brachybotrys.
Journal of natural products 1992;55(12):1776-8.
1992: Konoshima T; Kokumai M; Kozuka M; Iinuma M; Mizuno M; Tanaka T; Tokuda H; Nishino H; Iwashima A
Studies on inhibitors of skin tumor promotion. XI. Inhibitory effects of flavonoids from Scutellaria baicalensis on Epstein-Barr virus activation and their anti-tumor-promoting activities.
Chemical & pharmaceutical bulletin 1992;40(2):531-3.
1991: Konoshima T; Kozuka M
Constituents of leguminous plants, XIII. New triterpenoid saponins from Wistaria brachybotrys.
Journal of natural products 1991;54(3):830-6.
1991: Konoshima T; Kozuka M; Tokuda H; Nishino H; Iwashima A; Haruna M; Ito K; Tanabe M
Studies on inhibitors of skin tumor promotion, IX. Neolignans from Magnolia officinalis.
Journal of natural products 1991;54(3):816-22.
1991: Tokuda H; Konoshima T; Kozuka M; Kimura T
Inhibition of 12-O-tetradecanoylphorbol-13-acetate-promoted mouse skin papilloma by saponins.
Oncology 1991;48(1):77-80.
1990: Takasaki M; Konoshima T; Fujitani K; Yoshida S; Nishimura H; Tokuda H; Nishino H; Iwashima A; Kozuka M
Inhibitors of skin-tumor promotion. VIII. Inhibitory effects of euglobals and their related compounds on Epstein-Barr virus activation. (1).
Chemical & pharmaceutical bulletin 1990;38(10):2737-9.
1990: Takasaki M; Konoshima T; Shingu T; Tokuda H; Nishino H; Iwashima A; Kozuka M
Structures of euglobal-G1, -G2, and -G3 from Eucalyptus grandis, three new inhibitors of Epstein-Barr virus activation.
Chemical & pharmaceutical bulletin 1990;38(5):1444-6.
1989: Konoshima T; Kozuka M; Tokuda H; Tanabe M
[Anti-tumor promoting activities and inhibitory effects on Epstein-Barr virus activation of Shi-un-kou and its constituents]
Yakugaku zasshi : Journal of the Pharmaceutical Society of Japan 1989;109(11):843-6.
1989: Konoshima T; Kozuka M; Koyama J; Okatani T; Tagahara K; Tokuda H
Studies on inhibitors of skin tumor promotion, VI. Inhibitory effects of quinones on Epstein-Barr virus activation.
Journal of natural products 1989;52(5):987-95.
1989: Diallo B; Vanhaelen M; Vanhaelen-Fastré R; Konoshima T; Kozuka M; Tokuda H
Studies on inhibitors of skin-tumor promotion. Inhibitory effects of triterpenes from Cochlospermum tinctorium on Epstein-Barr virus activation.
Journal of natural products 1989;52(4):879-81.
1988: Konoshima T; Okamoto E; Kozuka M; Nishino H; Tokuda H; Tanabe M
Studies on inhibitors of skin tumor promotion, III. Inhibitory effects of isoflavonoids from Wisteria brachybotrys on Epstein-Barr virus activation.
Journal of natural products 1988;51(6):1266-70.
1988: Tokuda H; Konoshima T; Kozuka M; Kimura T
Inhibitory effects of 12-O-tetradecanoylphorbol-13-acetate and teleocidin B induced Epstein-Barr virus by saponin and its related compounds.
Cancer letters 1988;40(3):309-17.
1987: Konoshima T; Takasaki M; Kozuka M; Tokuda H
Studies on inhibitors of skin-tumor promotion, I. Inhibitory effects of triterpenes from Euptelea polyandra on Epstein-Barr virus activation.
Journal of natural products 1987;50(6):1167-70.

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Takao Konoshima

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