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Dennis Koop

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Dennis R Koop; Myrna Y Munar; Lisa A Bleyle; Ganesh Cherala; Amira Al-Uzri
Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry.
Blair U Bradford; Eric F Lock; Oksana Kosyk; Sungkyoon Kim; Takeki Uehara; David Harbourt; Michelle DeSimone; David Threadgill; Volodymyr Tryndyak; Igor P Pogribny; Lisa Bleyle; Dennis R Koop; Ivan Rusyn
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice.
Christine L Powell; Blair U Bradford; Christopher Patrick Craig; Masato Tsuchiya; Takeki Uehara; Thomas M O'Connell; Igor P Pogribny; Stepan Melnyk; Dennis R Koop; Lisa Bleyle; David Threadgill; Ivan Rusyn
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.

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2013: Dennis R Koop; Myrna Y Munar; Lisa A Bleyle; Ganesh Cherala; Amira Al-Uzri
Analysis of tacrolimus and creatinine from a single dried blood spot using liquid chromatography tandem mass spectrometry.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2013;926():54-61.
2011: Blair U Bradford; Eric F Lock; Oksana Kosyk; Sungkyoon Kim; Takeki Uehara; David Harbourt; Michelle DeSimone; David Threadgill; Volodymyr Tryndyak; Igor P Pogribny; Lisa Bleyle; Dennis R Koop; Ivan Rusyn
Interstrain differences in the liver effects of trichloroethylene in a multistrain panel of inbred mice.
Toxicological sciences : an official journal of the Society of Toxicology 2011;120(1):206-17.
2010: Christine L Powell; Blair U Bradford; Christopher Patrick Craig; Masato Tsuchiya; Takeki Uehara; Thomas M O'Connell; Igor P Pogribny; Stepan Melnyk; Dennis R Koop; Lisa Bleyle; David Threadgill; Ivan Rusyn
Mechanism for prevention of alcohol-induced liver injury by dietary methyl donors.
Toxicological sciences : an official journal of the Society of Toxicology 2010;115(1):131-9.
2010: Vijayshree Yadav; Gail H Marracci; Myrna Y Munar; Ganesh Cherala; Lauren E Stuber; Lilia Alvarez; Lynne Shinto; Dennis R Koop; Dennis N Bourdette
Pharmacokinetic study of lipoic acid in multiple sclerosis: comparing mice and human pharmacokinetic parameters.
Multiple sclerosis (Houndmills, Basingstoke, England) 2010;16(4):387-97.
2008: Wenri Zhang; Takashi Otsuka; Nobuo Sugo; A Ardeshiri; Yazan K Alhadid; Jeffrey Iliff; Andrea DeBarber; Dennis R Koop; Nabil Alkayed
Soluble epoxide hydrolase gene deletion is protective against experimental cerebral ischemia.
Stroke; a journal of cerebral circulation 2008;39(7):2073-8.
2008: James H Peters; Stuart McDougall; David Mendelowitz; Dennis R Koop; Michael Andresen
Isoflurane differentially modulates inhibitory and excitatory synaptic transmission to the solitary tract nucleus.
Anesthesiology 2008;108(4):675-83.
2008: Stuart McDougall; James H Peters; Lia LaBrant; Xin Wang; Dennis R Koop; Michael Andresen
Paired assessment of volatile anesthetic concentrations with synaptic actions recorded in vitro.
PloS one 2008;3(10):e3372.
2007: Ines P Koerner; Rachel Jacks; Andrea DeBarber; Dennis R Koop; Peizhong Mao; David F Grant; Nabil Alkayed
Polymorphisms in the human soluble epoxide hydrolase gene EPHX2 linked to neuronal survival after ischemic injury.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(17):4642-9.
2006: Jennifer L Lycette; Carrie L Dul; Myrna Munar; Donna Belle; Stephen Y (Steve) Chui; Dennis R Koop; Craig Nichols
Effect of pregnancy on the pharmacokinetics of paclitaxel: a case report.
Clinical breast cancer 2006;7(4):342-4.
2006: Dennis R Koop
Alcohol metabolism's damaging effects on the cell: a focus on reactive oxygen generation by the enzyme cytochrome P450 2E1.
Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism 2006;29(4):274-80.
2005: Qing-Gao Deng; Hongyun She; Jason H Cheng; Samuel W French; Dennis R Koop; Shigang Xiong; Hidekazu Tsukamoto
Steatohepatitis induced by intragastric overfeeding in mice.
Hepatology (Baltimore, Md.) 2005;42(4):905-14.
2005: Raj Lakshman; Arthur I Cederbaum; Jan B Hoek; Masahiro Konishi; Dennis R Koop; Terrence M Donohu
Use of CYP2E1-transfected human liver cell lines in elucidating the actions of ethanol.
Alcoholism, clinical and experimental research 2005;29(9):1726-34.
2005: Amala Soumyanath; Yong-Ping Zhong; Sandra A Gold; Xiaolin Yu; Dennis R Koop; Dennis N Bourdette; Bruce G Gold
Centella asiatica accelerates nerve regeneration upon oral administration and contains multiple active fractions increasing neurite elongation in-vitro.
The Journal of pharmacy and pharmacology 2005;57(9):1221-9.
2005: Blair U Bradford; Hiroshi Kono; Fuyumi Isayama; Oksana Kosyk; Michael D Wheeler; Taro E Akiyama; Lisa Bleye; Kristopher W Krausz; Frank J Gonzalez; Dennis R Koop; Ivan Rusyn
Cytochrome P450 CYP2E1, but not nicotinamide adenine dinucleotide phosphate oxidase, is required for ethanol-induced oxidative DNA damage in rodent liver.
Hepatology (Baltimore, Md.) 2005;41(2):336-44.
2005: Charles D Blanke; Nora Mattek; Thomas G Deloughery; Dennis R Koop
A phase I study of 5-fluorouracil, leucovorin, and celecoxib in patients with incurable colorectal cancer.
Prostaglandins & other lipid mediators 2005;75(1-4):169-72.
2004: Jianya Huan; John M Streicher; Lisa A Bleyle; Dennis R Koop
Proteasome-dependent degradation of cytochromes P450 2E1 and 2B1 expressed in tetracycline-regulated HeLa cells.
Toxicology and applied pharmacology 2004;199(3):332-43.
2004: Andrea DeBarber; Lisa A Bleyle; Jean-Baptiste Roullet; Dennis R Koop
Omega-hydroxylation of farnesol by mammalian cytochromes p450.
Biochimica et biophysica acta 2004;1682(1-3):18-27.
2004: Jörn M Schattenberg; Yongjun Wang; Raina M Rigoli; Dennis R Koop; Mark J Czaja
CYP2E1 overexpression alters hepatocyte death from menadione and fatty acids by activation of ERK1/2 signaling.
Hepatology (Baltimore, Md.) 2004;39(2):444-55.
2003: Fuyumi Isayama; Matthias Froh; Blair U Bradford; Stephen E McKim; Maria B Kadiiska; Henry D Connor; Ronald P Mason; Dennis R Koop; Michael D Wheeler; Gavin E Arteel
The CYP inhibitor 1-aminobenzotriazole does not prevent oxidative stress associated with alcohol-induced liver injury in rats and mice.
Free radical biology & medicine 2003;35(12):1568-81.
2003: Alina L Micu; Sharon Miksys; Edward M Sellers; Dennis R Koop; Rachel F Tyndale
Rat hepatic CYP2E1 is induced by very low nicotine doses: an investigation of induction, time course, dose response, and mechanism.
The Journal of pharmacology and experimental therapeutics 2003;306(3):941-7.
2003: Teri L Wadsworth; Hataya Poonyagariyagorn; Elinor L Sullivan; Dennis R Koop; Charles E Roselli
In vivo effect of PC-SPES on prostate growth and hepatic CYP3A expression in rats.
The Journal of pharmacology and experimental therapeutics 2003;306(1):187-94.
2003: Margit Spatzenegger; Hong Liu; Qinmi Wang; Andrea DeBarber; Dennis R Koop; James Halpert
Analysis of differential substrate selectivities of CYP2B6 and CYP2E1 by site-directed mutagenesis and molecular modeling.
The Journal of pharmacology and experimental therapeutics 2003;304(1):477-87.
2002: Brett E Jones; Hailing Liu; Chau R Lo; Dennis R Koop; Mark J Czaja
Cytochrome P450 2E1 expression induces hepatocyte resistance to cell death from oxidative stress.
Antioxidants & redox signaling 2002;4(5):701-9.
2001: Teri L Wadsworth; T L McDonald; Dennis R Koop
Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced signaling pathways involved in the release of tumor necrosis factor-alpha.
Biochemical pharmacology 2001;62(7):963-74.
2001: Teri L Wadsworth; Dennis R Koop
Effects of Ginkgo biloba extract (EGb 761) and quercetin on lipopolysaccharide-induced release of nitric oxide.
Chemico-biological interactions 2001;137(1):43-58.
2001: CA Rivera; Blair U Bradford; K J Hunt; Y Adachi; Laura W Schrum; Dennis R Koop; ER Burchardt; Richard A Rippe; Ronald G Thurman
Attenuation of CCl(4)-induced hepatic fibrosis by GdCl(3) treatment or dietary glycine.
American journal of physiology. Gastrointestinal and liver physiology 2001;281(1):G200-7.
1999: Hiroshi Kono; Blair U Bradford; M Yin; Kathleen K Sulik; Dennis R Koop; J M Peters; F J Gonzalez; T McDonald; Anna Dikalova; Maria B Kadiiska; Ronald P Mason; Ronald G Thurman
CYP2E1 is not involved in early alcohol-induced liver injury.
The American journal of physiology 1999;277(6 Pt 1):G1259-67.
1999: H Downes; Dennis R Koop; Bethany Jill Klopfenstein; N Lessov
Retention of nociceptor responses during deep barbiturate anesthesia in frogs.
Comparative biochemistry and physiology. Part C, Pharmacology, toxicology & endocrinology 1999;124(2):203-10.
1999: Teri L Wadsworth; Dennis R Koop
Effects of the wine polyphenolics quercetin and resveratrol on pro-inflammatory cytokine expression in RAW 264.7 macrophages.
Biochemical pharmacology 1999;57(8):941-9.
1999: Jianya Huan; Dennis R Koop
Tightly regulated and inducible expression of rabbit CYP2E1 using a tetracycline-controlled expression system.
Drug metabolism and disposition: the biological fate of chemicals 1999;27(4):549-54.
1999: Robert L Haining; Jeffrey P Jones; Kirk R Henne; Michael B Fisher; Dennis R Koop; William F Trager; Allan E Rettie
Enzymatic determinants of the substrate specificity of CYP2C9: role of B'-C loop residues in providing the pi-stacking anchor site for warfarin binding.
Biochemistry 1999;38(11):3285-92.
1998: R Jin; Dennis R Koop; Judy L Raucy; Jerome M Lasker
Role of human CYP4F2 in hepatic catabolism of the proinflammatory agent leukotriene B4.
Archives of biochemistry and biophysics 1998;359(1):89-98.
1998: Lane J Brunner; W M Bennett; Dennis R Koop
Cyclosporine suppresses rat hepatic cytochrome P450 in a time-dependent manner.
Kidney international 1998;54(1):216-23.
1998: JL Nieusma; David J Claffey; Dennis R Koop; W Chen; Raimund Peter; Sidney D Nelson; James A Ruth; David Ross
Oxidation of 1,3-butadiene to (R)- and (S)-butadiene monoxide by purified recombinant cytochrome P450 2E1 from rabbit, rat and human.
Toxicology letters 1998;95(2):123-9.
1998: X Guan; Michael B Fisher; DH Lang; Yi-Min Zheng; Dennis R Koop; Allan E Rettie
Cytochrome P450-dependent desaturation of lauric acid: isoform selectivity and mechanism of formation of 11-dodecenoic acid.
Chemico-biological interactions 1998;110(1-2):103-21.
1997: Dennis R Koop; Bethany Jill Klopfenstein; Y Iimuro; R G Thurman
Gadolinium chloride blocks alcohol-dependent liver toxicity in rats treated chronically with intragastric alcohol despite the induction of CYP2E1.
Molecular pharmacology 1997;51(6):944-50.
1997: Samuel W French; M Morimoto; R C Reitz; Dennis R Koop; Bethany Jill Klopfenstein; K Estes; P Clot; Magnus Ingelman-Sundberg; Emanuele Albano
Lipid peroxidation, CYP2E1 and arachidonic acid metabolism in alcoholic liver disease in rats.
The Journal of nutrition 1997;127(5 Suppl):907S-911S.
1997: MB Sewer; Dennis R Koop; Edward T Morgan
Differential inductive and suppressive effects of endotoxin and particulate irritants on hepatic and renal cytochrome P-450 expression.
The Journal of pharmacology and experimental therapeutics 1997;280(3):1445-54.
1997: christian helvig; C Alayrac; C Mioskowski; Dennis R Koop; D Poullain; Francis Durst; Jean-Pierre Salaun
Suicide inactivation of cytochrome P450 by midchain and terminal acetylenes. A mechanistic study of inactivation of a plant lauric acid omega-hydroxylase.
The Journal of biological chemistry 1997;272(1):414-21.
1996: R M Laethem; M Balazy; Dennis R Koop
Epoxidation of C18 unsaturated fatty acids by cytochromes P4502C2 and P4502CAA.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(6):664-8.
1996: L J Brunner; W M Bennett; Dennis R Koop
Selective suppression of rat hepatic microsomal activity during chronic cyclosporine nephrotoxicity.
The Journal of pharmacology and experimental therapeutics 1996;277(3):1710-8.
1996: MB Sewer; Dennis R Koop; Edward T Morgan
Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(4):401-7.
1995: S Barmada; E Kienle; Dennis R Koop
Rabbit P450 2E1 expressed in CHO-K1 cells has a short half-life.
Biochemical and biophysical research communications 1995;206(2):601-7.
1994: B E Daikh; Jerome M Lasker; Judy L Raucy; Dennis R Koop
Regio- and stereoselective epoxidation of arachidonic acid by human cytochromes P450 2C8 and 2C9.
The Journal of pharmacology and experimental therapeutics 1994;271(3):1427-33.
1994: B E Daikh; R M Laethem; Dennis R Koop
Stereoselective epoxidation of arachidonic acid by cytochrome P-450s 2CAA and 2C2.
The Journal of pharmacology and experimental therapeutics 1994;269(3):1130-5.
1994: R M Laethem; James Halpert; Dennis R Koop
Epoxidation of arachidonic acid as an active-site probe of cytochrome P-450 2B isoforms.
Biochimica et biophysica acta 1994;1206(1):42-8.
1994: Paul C Howard; M E McManus; Dennis R Koop
The role of cytochrome P450 2C3 in rabbit liver microsomal metabolism of 1-nitropyrene and 3-nitrofluoranthene.
Journal of biochemical toxicology 1994;9(2):71-8.
1993: Gregory L Kedderis; R Batra; Dennis R Koop
Epoxidation of acrylonitrile by rat and human cytochromes P450.
Chemical research in toxicology 1993;6(6):866-71.
1993: Marc Thibonnier; A L Bayer; C L Laethem; Dennis R Koop; Michael S Simonson
Role of eicosanoids in vasopressin-induced calcium mobilization in A7r5 vascular smooth muscle cells.
The American journal of physiology 1993;265(1 Pt 1):E108-14.
1993: R M Laethem; M Balazy; J R Falck; C L Laethem; Dennis R Koop
Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1.
The Journal of biological chemistry 1993;268(17):12912-8.
1992: R M Laethem; Dennis R Koop
Identification of rabbit cytochromes P450 2C1 and 2C2 as arachidonic acid epoxygenases.
Molecular pharmacology 1992;42(6):958-63.
1992: T Castillo; Dennis R Koop; S Kamimura; George Triadafilopoulos; H Tsukamoto
Role of cytochrome P-450 2E1 in ethanol-, carbon tetrachloride- and iron-dependent microsomal lipid peroxidation.
Hepatology (Baltimore, Md.) 1992;16(4):992-6.
1992: Dennis R Koop; C L Laethem
Inhibition of rabbit microsomal cytochrome P-450 2E1-dependent p-nitrophenol hydroxylation by substituted benzene derivatives.
Drug metabolism and disposition: the biological fate of chemicals 1992;20(5):775-7.
1992: R M Laethem; C L Laethem; X Ding; Dennis R Koop
P-450-dependent arachidonic acid metabolism in rabbit olfactory microsomes.
The Journal of pharmacology and experimental therapeutics 1992;262(1):433-8.
1992: R M Laethem; C L Laethem; Dennis R Koop
Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex.
The Journal of biological chemistry 1992;267(8):5552-9.
1992: D J Tierney; A L Haas; Dennis R Koop
Degradation of cytochrome P450 2E1: selective loss after labilization of the enzyme.
Archives of biochemistry and biophysics 1992;293(1):9-16.
1992: Dennis R Koop
Oxidative and reductive metabolism by cytochrome P450 2E1.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1992;6(2):724-30.
1991: Dennis R Koop; A Chernosky; E P Brass
Identification and induction of cytochrome P450 2E1 in rat Kupffer cells.
The Journal of pharmacology and experimental therapeutics 1991;258(3):1072-6.
1991: Dennis R Koop; R M Laethem; A L Goldner; J G Douglas
Cytochrome P450 expression and metabolism in isolated rabbit renal epithelium.
Methods in enzymology 1991;206():364-71.
1990: Dennis R Koop; D J Tierney
Multiple mechanisms in the regulation of ethanol-inducible cytochrome P450IIE1.
BioEssays : news and reviews in molecular, cellular and developmental biology 1990;12(9):429-35.
1990: Dennis R Koop
Inhibition of ethanol-inducible cytochrome P450IIE1 by 3-amino-1,2,4-triazole.
Chemical research in toxicology 1990;3(4):377-83.
1989: L A Clejan; Dennis R Koop; Arthur I Cederbaum
Sensitivity of the rat liver microsomal oxidation of pyrazole to antibody raised against the ethanol-inducible rabbit liver cytochrome P-450 isozyme.
Drug metabolism and disposition: the biological fate of chemicals 1989;17(6):694-8.
1989: G G Schnier; C L Laethem; Dennis R Koop
Identification and induction of cytochromes P450, P450IIE1 and P450IA1 in rabbit bone marrow.
The Journal of pharmacology and experimental therapeutics 1989;251(2):790-6.
1989: J Hoffman; K Konopka; C Buckhorn; Dennis R Koop; Lucy Waskell
Ethanol-inducible cytochrome P450 in rabbits metabolizes enflurane.
British journal of anaesthesia 1989;63(1):103-8.
1989: Dennis R Koop; C L Laethem; G G Schnier
Identification of ethanol-inducible P450 isozyme 3a (P450IIE1) as a benzene and phenol hydroxylase.
Toxicology and applied pharmacology 1989;98(2):278-88.
1989: G D McCoy; G J DeMarco; Dennis R Koop
Microsomal nicotine metabolism: a comparison of relative activities of six purified rabbit cytochrome P-450 isozymes.
Biochemical pharmacology 1989;38(7):1185-8.
1989: Jacqueline F Sinclair; Sheryl G Wood; E L Smith; Peter R Sinclair; Dennis R Koop
Comparison of the form(s) of cytochrome P-450 induced by ethanol and glutethimide in cultured chick hepatocytes.
Biochemical pharmacology 1989;38(4):657-64.
1989: Dennis R Koop; C L Laethem; D J Tierney
The utility of p-nitrophenol hydroxylation in P450IIE1 analysis.
Drug metabolism reviews 1989;20(2-4):541-51.
1988: L D Gruenke; K Konopka; Dennis R Koop; Lucy Waskell
Characterization of halothane oxidation by hepatic microsomes and purified cytochromes P-450 using a gas chromatographic mass spectrometric assay.
The Journal of pharmacology and experimental therapeutics 1988;246(2):454-9.
1988: Paul C Howard; K A Reed; Dennis R Koop
Oxidative metabolism of 1-nitropyrene by rabbit liver microsomes and purified microsomal cytochrome P-450 isozymes.
Cancer research 1988;48(15):4261-5.
1988: G D McCoy; Dennis R Koop
Reconstitution of rabbit liver microsomal N-nitrosopyrrolidine alpha-hydroxylase activity.
Cancer research 1988;48(14):3987-92.
1988: J A Handler; Dennis R Koop; M J Coon; Y Takei; Ronald G Thurman
Identification of P-450ALC in microsomes from alcohol dehydrogenase-deficient deermice: contribution to ethanol elimination in vivo.
Archives of biochemistry and biophysics 1988;264(1):114-24.
1988: G D McCoy; Dennis R Koop
Biochemical and immunochemical evidence for the induction of an ethanol-inducible cytochrome P-450 isozyme in male Syrian golden hamsters.
Biochemical pharmacology 1988;37(8):1563-8.
1987: Judy L Raucy; P Fernandes; M Black; S L Yang; Dennis R Koop
Identification of a human liver cytochrome P-450 exhibiting catalytic and immunochemical similarities to cytochrome P-450 3a of rabbit liver.
Biochemical pharmacology 1987;36(18):2921-6.
1987: S C Khani; P G Zaphiropoulos; V S Fujita; T D Porter; Dennis R Koop; Minor J Coon
cDNA and derived amino acid sequence of ethanol-inducible rabbit liver cytochrome P-450 isozyme 3a (P-450ALC).
Proceedings of the National Academy of Sciences of the United States of America 1987;84(3):638-42.
1987: M J Coon; Dennis R Koop
Alcohol-inducible cytochrome P-450 (P-450ALC).
Archives of toxicology 1987;60(1-3):16-21.
1986: X X Ding; Dennis R Koop; B L Crump; M J Coon
Immunochemical identification of cytochrome P-450 isozyme 3a (P-450ALC) in rabbit nasal and kidney microsomes and evidence for differential induction by alcohol.
Molecular pharmacology 1986;30(4):370-8.
1986: D E Ryan; Dennis R Koop; P E Thomas; M J Coon; W Levin
Evidence that isoniazid and ethanol induce the same microsomal cytochrome P-450 in rat liver, an isozyme homologous to rabbit liver cytochrome P-450 isozyme 3a.
Archives of biochemistry and biophysics 1986;246(2):633-44.
1986: Dennis R Koop
Hydroxylation of p-nitrophenol by rabbit ethanol-inducible cytochrome P-450 isozyme 3a.
Molecular pharmacology 1986;29(4):399-404.
1986: Dennis R Koop; M J Coon
Ethanol oxidation and toxicity: role of alcohol P-450 oxygenase.
Alcoholism, clinical and experimental research 1986;10(6 Suppl):44S-49S.
1985: K A Holm; Dennis R Koop; M J Coon; A D Theoharides; David Kupfer
omega-1 and omega-2 hydroxylation of prostaglandins by rabbit hepatic microsomal cytochrome P-450 isozyme 6.
Archives of biochemistry and biophysics 1985;243(1):135-43.
1985: Dennis R Koop; J P Casazza
Identification of ethanol-inducible P-450 isozyme 3a as the acetone and acetol monooxygenase of rabbit microsomes.
The Journal of biological chemistry 1985;260(25):13607-12.
1985: Dennis R Koop; B L Crump; G D Nordblom; M J Coon
Immunochemical evidence for induction of the alcohol-oxidizing cytochrome P-450 of rabbit liver microsomes by diverse agents: ethanol, imidazole, trichloroethylene, acetone, pyrazole, and isoniazid.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(12):4065-9.
1985: C S Yang; Dennis R Koop; T Y Wang; M J Coon
Immunochemical studies on the metabolism of nitrosamines by ethanol-inducible cytochrome P-450.
Biochemical and biophysical research communications 1985;128(2):1007-13.
1985: C S Yang; Y Y Tu; Dennis R Koop; M J Coon
Metabolism of nitrosamines by purified rabbit liver cytochrome P-450 isozymes.
Cancer research 1985;45(3):1140-5.
1985: D M Kokkinakis; Dennis R Koop; DG Scarpelli; M J Coon; Paul Hollenberg
Metabolism of N-nitroso-2,6-dimethylmorpholine by isozymes of rabbit liver microsomal cytochrome P-450.
Cancer research 1985;45(2):619-24.
1985: Dennis R Koop; M J Coon
Role of alcohol P-450-oxygenase (APO) in microsomal ethanol oxidation.
Alcohol (Fayetteville, N.Y.) 1985;2(1):23-6.
1984: Dennis R Koop; G D Nordblom; M J Coon
Immunochemical evidence for a role of cytochrome P-450 in liver microsomal ethanol oxidation.
Archives of biochemistry and biophysics 1984;235(1):228-38.
1984: P E Thomas; J Reidy; L M Reik; D E Ryan; Dennis R Koop; W Levin
Use of monoclonal antibody probes against rat hepatic cytochromes P-450c and P-450d to detect immunochemically related isozymes in liver microsomes from different species.
Archives of biochemistry and biophysics 1984;235(1):239-53.
1984: V S Fujita; S D Black; G E Tarr; Dennis R Koop; Minor J Coon
On the amino acid sequence of cytochrome P-450 isozyme 4 from rabbit liver microsomes.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(14):4260-4.
1984: L D Gorsky; Dennis R Koop; M J Coon
On the stoichiometry of the oxidase and monooxygenase reactions catalyzed by liver microsomal cytochrome P-450. Products of oxygen reduction.
The Journal of biological chemistry 1984;259(11):6812-7.
1984: Dennis R Koop; M J Coon
Purification of liver microsomal cytochrome P-450 isozymes 3a and 6 from imidazole-treated rabbits. Evidence for the identity of isozyme 3a with the form obtained by ethanol treatment.
Molecular pharmacology 1984;25(3):494-501.
1984: M J Coon; Dennis R Koop; L E Reeve; B L Crump
Alcohol metabolism and toxicity: role of cytochrome P-450.
Fundamental and applied toxicology : official journal of the Society of Toxicology 1984;4(2 Pt 1):134-43.
1983: E T Morgan; Dennis R Koop; M J Coon
Comparison of six rabbit liver cytochrome P-450 isozymes in formation of a reactive metabolite of acetaminophen.
Biochemical and biophysical research communications 1983;112(1):8-13.
1983: M J Coon; Dennis R Koop; E T Morgan
Alcohol oxidation by isozyme 3a of liver microsomal cytochrome P-450.
Pharmacology, biochemistry, and behavior 1983;18 Suppl 1():177-80.
1982: E T Morgan; Dennis R Koop; M J Coon
Catalytic activity of cytochrome P-450 isozyme 3a isolated from liver microsomes of ethanol-treated rabbits. Oxidation of alcohols.
The Journal of biological chemistry 1982;257(23):13951-7.
1982: M Delaforge; Dennis R Koop; M J Coon
Role of isosafrole as complexing agent and inducer of P-450LM4 in rabbit liver microsomes.
Biochemical and biophysical research communications 1982;108(1):59-65.
1982: Dennis R Koop; E T Morgan; G E Tarr; Minor J Coon
Purification and characterization of a unique isozyme of cytochrome P-450 from liver microsomes of ethanol-treated rabbits.
The Journal of biological chemistry 1982;257(14):8472-80.
1981: M T Huang; E F Johnson; U Muller-Eberhard; Dennis R Koop; M J Coon; A H Conney
Specificity in the activation and inhibition by flavonoids of benzo[a]pyrene hydroxylation by cytochrome P-450 isozymes from rabbit liver microsomes.
The Journal of biological chemistry 1981;256(21):10897-901.
1981: Dennis R Koop; A V Persson; M J Coon
Properties of electrophoretically homogeneous constitutive forms of liver microsomal cytochrome P-450.
The Journal of biological chemistry 1981;256(20):10704-11.
1980: G L Kedderis; Dennis R Koop; Paul Hollenberg
N-Demethylation reactions catalyzed by chloroperoxidase.
The Journal of biological chemistry 1980;255(21):10174-82.
1980: Dennis R Koop; Paul Hollenberg
Kinetics of the hydroperoxide-dependent dealkylation reactions catalyzed by rabbit liver microsomal cytochrome P-450.
The Journal of biological chemistry 1980;255(20):9685-92.
1980: Raymond F Novak; Dennis R Koop; Paul Hollenberg
Liver microsomal metabolism of N-methylcarbazole: structural identification of the four major metabolites of N-methylcarbazole using 1H Fourier transform NMR spectroscopy.
Molecular pharmacology 1980;17(1):128-36.
1980: Dennis R Koop; Paul Hollenberg
Liver microsomal metabolism of N-methylcarbazole: a probe for induction, inhibition, and species differences.
Molecular pharmacology 1980;17(1):118-27.
1979: Dennis R Koop; M J Coon
Purification and properties of P-450LM3b, a constitutive form of cytochrome P-450, from rabbit liver microsomes.
Biochemical and biophysical research communications 1979;91(3):1075-81.
1977: L Tobian; J Lange; S Azar; J Iwai; Dennis R Koop; K Coffee
Reduction of intrinsic natriuretic capacity in kidneys of Dahl hypertension-prone rats.
Transactions of the Association of American Physicians 1977;90():401-6.