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Pavla Kopecková
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88
Kopecek, Jindrich
12
Lu, Zheng-Rong
12
Minko, Tamara
12
Wang, Dong
7
Tijerina, Monica
7
Miller, Scott
6
Peterson, Matthew
6
Gao, Song-Qi
5
Liu, Jihua
5
Jensen, Keith
5
Omelyanenko, V
5
Sun, Yongen
5
Shiah, Jane-Guo
5
Sima, Monika
4
Nori, Aparna
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All Publications
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2009: Gao Song-Qi; Sun Yongen; Kopecková Pavla; Peterson C Matthew; Kopecek Jindrich
Antitumor efficacy of colon-specific HPMA copolymer/9-aminocamptothecin conjugates in mice bearing human-colon carcinoma xenografts.
Macromolecular bioscience 2009;9(11):1135-42.
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2009: Liu Jihua; Kopecková Pavla; Bühler Patrick; Wolf Philipp; Pan Huaizhong; Bauer Hillevi; Elsässer-Beile Ursula; Kopecek Jindrich
Biorecognition and subcellular trafficking of HPMA copolymer-anti-PSMA antibody conjugates by prostate cancer cells.
Molecular pharmaceutics 2009;6(3):959-70.
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2009: Johnson Russell N; Kopecková Pavla; Kopecek Jindrich
Synthesis and evaluation of multivalent branched HPMA copolymer-Fab' conjugates targeted to the B-cell antigen CD20.
Bioconjugate chemistry 2009;20(1):129-37.
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2009: Segal Ehud; Pan Huaizhong; Ofek Paula; Udagawa Taturo; Kopecková Pavla; Kopecek Jindrich; Satchi-Fainaro Ronit
Targeting angiogenesis-dependent calcified neoplasms using combined polymer therapeutics.
PloS one 2009;4(4):e5233.
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2008: Miller S C; Pan H; Wang D; Bowman B M; Kopecková P; Kopecek J
Feasibility of using a bone-targeted, macromolecular delivery system coupled with prostaglandin E(1) to promote bone formation in aged, estrogen-deficient rats.
Pharmaceutical research 2008;25(12):2889-95.
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2008: Yuan Weiwei; Yang Jiyuan; Kopecková Pavla; Kopecek Jindrich
Smart hydrogels containing adenylate kinase: translating substrate recognition into macroscopic motion.
Journal of the American Chemical Society 2008;130(47):15760-1.
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2008: Cuchelkar Vaikunth; Kopecková Pavla; Kopecek Jindrich
Novel HPMA copolymer-bound constructs for combined tumor and mitochondrial targeting.
Molecular pharmaceutics 2008;5(5):776-86.
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2008: Hongrapipat Jarunee; Kopecková Pavla; Liu Jihua; Prakongpan Sompol; Kopecek Jindrich
Combination chemotherapy and photodynamic therapy with fab' fragment targeted HPMA copolymer conjugates in human ovarian carcinoma cells.
Molecular pharmaceutics 2008;5(5):696-709.
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2008: Pan Huaizhong; Sima Monika; Kopecková Pavla; Wu Kuangshi; Gao Songqi; Liu Jihua; Wang Dong; Miller Scott C; Kopecek Jindrich
Biodistribution and pharmacokinetic studies of bone-targeting N-(2-hydroxypropyl)methacrylamide copolymer-alendronate conjugates.
Molecular pharmaceutics 2008;5(4):548-58.
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2008: Pan Huaizhong; Liu Jihua; Dong Yuanyi; Sima Monika; Kopecková Pavla; Brandi Maria Luisa; Kopecek Jindrich
Release of prostaglandin E(1) from N-(2-hydroxypropyl)methacrylamide copolymer conjugates by bone cells.
Macromolecular bioscience 2008;8(7):599-605.
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2008: Cuchelkar Vaikunth; Kopecková Pavla; Kopecek Jindrich
Synthesis and biological evaluation of disulfide-linked HPMA copolymer-mesochlorin e6 conjugates.
Macromolecular bioscience 2008;8(5):375-83.
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2008: Hongrapipat J; Kopecková P; Prakongpan S; Kopecek J
Enhanced antitumor activity of combinations of free and HPMA copolymer-bound drugs.
International journal of pharmaceutics 2008;351(1-2):259-70.
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2008: Gao Song-Qi; Sun Yongen; Kopecková Pavla; Peterson C Matthew; Kopecek Jindrich
Pharmacokinetic modeling of absorption behavior of 9-aminocamptothecin (9-AC) released from colon-specific HPMA copolymer-9-AC conjugate in rats.
Pharmaceutical research 2008;25(1):218-26.
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2007: Pan Huaizhong; Kopecková Pavla; Liu Jihua; Wang Dong; Miller Scott C; Kopecek Jindrich
Stability in plasmas of various species of HPMA copolymer-PGE1 conjugates.
Pharmaceutical research 2007;24(12):2270-80.
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2007: Malugin A; Kopecková P; Kopecek J
Liberation of doxorubicin from HPMA copolymer conjugate is essential for the induction of cell cycle arrest and nuclear fragmentation in ovarian carcinoma cells.
Journal of controlled release : official journal of the Controlled Release Society 2007;124(1-2):6-10.
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2007: Wang Dong; Miller Scott C; Shlyakhtenko Luda S; Portillo Alexander M; Liu Xin-Ming; Papangkorn Kongnara; Kopecková Pavla; Lyubchenko Yuri; Higuchi William I; Kopecek Jindrich
Osteotropic Peptide that differentiates functional domains of the skeleton.
Bioconjugate chemistry 2007;18(5):1375-8.
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2007: Ding Hui; Kopecková Pavla; Kopecek Jindrich
Self-association properties of HPMA copolymers containing an amphipathic heptapeptide.
Journal of drug targeting 2007;15(7-8):465-74.
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2007: Gao Song-Qi; Lu Zheng-Rong; Kopecková Pavla; Kopecek Jindrich
Biodistribution and pharmacokinetics of colon-specific HPMA copolymer--9-aminocamptothecin conjugate in mice.
Journal of controlled release : official journal of the Controlled Release Society 2007;117(2):179-85.
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2006: Wang Dong; Sima Monika; Mosley R Lee; Davda Jasmine P; Tietze Nicole; Miller Scott C; Gwilt Peter R; Kopecková Pavla; Kopecek Jindrich
Pharmacokinetic and biodistribution studies of a bone-targeting drug delivery system based on N-(2-hydroxypropyl)methacrylamide copolymers.
Molecular pharmaceutics 2006;3(6):717-25.
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2006: Pan Huaizhong; Kopecková Pavla; Wang Dong; Yang Jiyuan; Miller Scott; Kopecek Jindrich
Water-soluble HPMA copolymer--prostaglandin E1 conjugates containing a cathepsin K sensitive spacer.
Journal of drug targeting 2006;14(6):425-35.
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2006: Malugin Alexander; Kopecková Pavla; Kopecek Jindrich
HPMA copolymer-bound doxorubicin induces apoptosis in ovarian carcinoma cells by the disruption of mitochondrial function.
Molecular pharmaceutics 2006;3(3):351-61.
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2006: Yang Jiyuan; Xu Chunyu; Kopecková Pavla; Kopecek Jindrich
Hybrid hydrogels self-assembled from HPMA copolymers containing peptide grafts.
Macromolecular bioscience 2006;6(3):201-9.
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2006: Chivukula Padmanabh; Dusek Karel; Wang Dong; Dusková-Smrcková Mirka; Kopecková Pavla; Kopecek Jindrich
Synthesis and characterization of novel aromatic azo bond-containing pH-sensitive and hydrolytically cleavable IPN hydrogels.
Biomaterials 2006;27(7):1140-51.
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2006: Gao Song-Qi; Lu Zheng-Rong; Petri Boris; Kopecková Pavla; Kopecek Jindrich
Colon-specific 9-aminocamptothecin-HPMA copolymer conjugates containing a 1,6-elimination spacer.
Journal of controlled release : official journal of the Controlled Release Society 2006;110(2):323-31.
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2005: Wang Dong; Miller Scott C; Kopecková Pavla; Kopecek Jindrich
Bone-targeting macromolecular therapeutics.
Advanced drug delivery reviews 2005;57(7):1049-76.
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2005: Miller Scott C; Wang Dong; Kopecková Pavla; Kopecek Jindrich
Biopolymer-based delivery systems for advanced imaging and skeletal tissue-specific therapeutics.
Journal of bone and mineral metabolism 2005;23 Suppl():103-8.
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2004: Wang Dong; Miller Scott C; Sima Monika; Parker Dennis; Buswell Henry; Goodrich K Craig; Kopecková Pavla; Kopecek Jindrich
The arthrotropism of macromolecules in adjuvant-induced arthritis rat model: a preliminary study.
Pharmaceutical research 2004;21(10):1741-9.
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2004: Wang D; Li W; Pechar M; Kopecková P; Brömme D; Kopecek J
Cathepsin K inhibitor-polymer conjugates: potential drugs for the treatment of osteoporosis and rheumatoid arthritis.
International journal of pharmaceutics 2004;277(1-2):73-9.
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2004: Malugin Alexander; Kopecková Pavla; Kopecek Jindrich
HPMA copolymer-bound doxorubicin induces apoptosis in human ovarian carcinoma cells by a Fas-independent pathway.
Molecular pharmaceutics 2004;1(3):174-82.
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2004: David A; Kopecková P; Minko Tamara; Rubinstein Abraham; Kopecek J
Design of a multivalent galactoside ligand for selective targeting of HPMA copolymer-doxorubicin conjugates to human colon cancer cells.
European journal of cancer (Oxford, England : 1990) 2004;40(1):148-57.
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2003: Nishiyama Nobuhiro; Nori Aparna; Malugin Alexander; Kasuya Yuji; Kopecková Pavla; Kopecek Jindrich
Free and N-(2-hydroxypropyl)methacrylamide copolymer-bound geldanamycin derivative induce different stress responses in A2780 human ovarian carcinoma cells.
Cancer research 2003;63(22):7876-82.
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2003: Merdan Thomas; Callahan Jon; Petersen Holger; Kunath Klaus; Bakowsky Udo; Kopecková Pavla; Kissel Thomas; Kopecek Jindrich
Pegylated polyethylenimine-Fab' antibody fragment conjugates for targeted gene delivery to human ovarian carcinoma cells.
Bioconjugate chemistry 2003;14(5):989-96.
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2003: Wang Dong; Miller Scott; Sima Monika; Kopecková Pavla; Kopecek Jindrich
Synthesis and evaluation of water-soluble polymeric bone-targeted drug delivery systems.
Bioconjugate chemistry 2003;14(5):853-9.
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2003: Nori Aparna; Jensen Keith D; Tijerina Monica; Kopecková Pavla; Kopecek Jindrich
Subcellular trafficking of HPMA copolymer-Tat conjugates in human ovarian carcinoma cells.
Journal of controlled release : official journal of the Controlled Release Society 2003;91(1-2):53-9.
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2003: Tijerina Monica; Kopecková Pavla; Kopecek Jindrich
Mechanisms of cytotoxicity in human ovarian carcinoma cells exposed to free Mce6 or HPMA copolymer-Mce6 conjugates.
Photochemistry and photobiology 2003;77(6):645-52.
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2003: Tijerina Monica; Kopecková Pavla; Kopecek Jindrich
Correlation of subcellular compartmentalization of HPMA copolymer-Mce6 conjugates with chemotherapeutic activity in human ovarian carcinoma cells.
Pharmaceutical research 2003;20(5):728-37.
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2003: Jensen Keith D; Nori Aparna; Tijerina Monica; Kopecková Pavla; Kopecek Jindrich
Cytoplasmic delivery and nuclear targeting of synthetic macromolecules.
Journal of controlled release : official journal of the Controlled Release Society 2003;87(1-3):89-105.
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2003: Nori Aparna; Jensen Keith D; Tijerina Monica; Kopecková Pavla; Kopecek Jindrich
Tat-conjugated synthetic macromolecules facilitate cytoplasmic drug delivery to human ovarian carcinoma cells.
Bioconjugate chemistry 2003;14(1):44-50.
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2003: Peterson C Matthew; Shiah Jane-Guo; Sun Yongen; Kopecková Pavla; Minko Tamara; Straight Richard C; Kopecek Jindrich
HPMA copolymer delivery of chemotherapy and photodynamic therapy in ovarian cancer.
Advances in experimental medicine and biology 2003;519():101-23.
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2002: Jensen Keith D; Kopecková Pavla; Kopecek Jindrich
Antisense oligonucleotides delivered to the lysosome escape and actively inhibit the hepatitis B virus.
Bioconjugate chemistry 2002;13(5):975-84.
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2002: David Ayelet; Kopecková Pavla; Kopecek Jindrich; Rubinstein Abraham
The role of galactose, lactose, and galactose valency in the biorecognition of N-(2-hydroxypropyl)methacrylamide copolymers by human colon adenocarcinoma cells.
Pharmaceutical research 2002;19(8):1114-22.
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2002: Wang Dong; Pechar Michal; Li Weijie; Kopecková Pavla; Brömme Dieter; Kopecek Jindrich
Inhibition of cathepsin K with lysosomotropic macromolecular inhibitors.
Biochemistry 2002;41(28):8849-59.
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2002: Kasuya Yuji; Lu Zheng-Rong; Kopecková Pavla; Tabibi S Esmail; Kopecek Jindrich
Influence of the structure of drug moieties on the in vitro efficacy of HPMA copolymer-geldanamycin derivative conjugates.
Pharmaceutical research 2002;19(2):115-23.
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2002: Lu Zheng-Rong; Shiah Jane-Guo; Sakuma Shinji; Kopecková Pavla; Kopecek Jindrich
Design of novel bioconjugates for targeted drug delivery.
Journal of controlled release : official journal of the Controlled Release Society 2002;78(1-3):165-73.
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2001: David A; Kopecková P; Rubinstein A; Kopecek J
Enhanced biorecognition and internalization of HPMA copolymers containing multiple or multivalent carbohydrate side-chains by human hepatocarcinoma cells.
Bioconjugate chemistry 2001;12(6):890-9.
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2001: Kasuya Y; Lu Z; Kopecková P; Kopecek J
Improved synthesis and evaluation of 17-substituted aminoalkylgeldanamycin derivatives applicable to drug delivery systems.
Bioorganic & medicinal chemistry letters 2001;11(16):2089-91.
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2001: Sakuma S; Lu Z R; Kopecková P; Kopecek J
Biorecognizable HPMA copolymer-drug conjugates for colon-specific delivery of 9-aminocamptothecin.
Journal of controlled release : official journal of the Controlled Release Society 2001;75(3):365-79.
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2001: Wróblewski S; Berenson M; Kopecková P; Kopecek J
Potential of lectin-N-(2-hydroxypropyl)methacrylamide copolymer-drug conjugates for the treatment of pre-cancerous conditions.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):283-93.
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2001: Tijerina M; Kopecková P; Kopecek J
The effects of subcellular localization of N-(2-hydroxypropyl)methacrylamide copolymer-Mce(6) conjugates in a human ovarian carcinoma.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):269-73.
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2001: Lu Z R; Shiah J G; Kopecková P; Kopecek J
Preparation and biological evaluation of polymerizable antibody Fab' fragment targeted polymeric drug delivery system.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):263-8.
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2001: Shiah J G; Sun Y; Kopecková P; Peterson C M; Straight R C; Kopecek J
Combination chemotherapy and photodynamic therapy of targetable N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin/mesochlorin e(6)-OV-TL 16 antibody immunoconjugates.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):249-53.
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2001: Kasuya Y; Lu Z R; Kopecková P; Minko T; Tabibi S E; Kopecek J
Synthesis and characterization of HPMA copolymer-aminopropylgeldanamycin conjugates.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):203-11.
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2001: Kopecek J; Kopecková P; Minko T; Lu Z R; Peterson C M
Water soluble polymers in tumor targeted delivery.
Journal of controlled release : official journal of the Controlled Release Society 2001;74(1-3):147-58.
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2001: Wróblewski S; Ríhová B; Rossmann P; Hudcovicz T; Reháková Z; Kopecková P; Kopecek J
The influence of a colonic microbiota on HPMA copolymer lectin conjugates binding in rodent intestine.
Journal of drug targeting 2001;9(2):85-94.
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2001: Minko T; Kopecková P; Kopecek J
Preliminary evaluation of caspases-dependent apoptosis signaling pathways of free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells.
Journal of controlled release : official journal of the Controlled Release Society 2001;71(3):227-37.
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2001: Lu Z R; Gao S Q; Kopecková P; Kopecek J
Modification of cyclosporin A and conjugation of its derivative to HPMA copolymers.
Bioconjugate chemistry 2001;12(1):129-33.
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2001: Shiah J G; Dvorák M; Kopecková P; Sun Y; Peterson C M; Kopecek J
Biodistribution and antitumour efficacy of long-circulating N-(2-hydroxypropyl)methacrylamide copolymer-doxorubicin conjugates in nude mice.
European journal of cancer (Oxford, England : 1990) 2001;37(1):131-9.
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2001: Jensen K D; Kopecková P; Bridge J H; Kopecek J
The cytoplasmic escape and nuclear accumulation of endocytosed and microinjected HPMA copolymers and a basic kinetic study in Hep G2 cells.
AAPS pharmSci 2001;3(4):E32.
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2000: Tijerina M; Fowers K D; Kopecková P; Kopecek J
Chronic exposure of human ovarian carcinoma cells to free or HPMA copolymer-bound mesochlorin e6 does not induce P-glycoprotein-mediated multidrug resistance.
Biomaterials 2000;21(21):2203-10.
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2000: Demoy M; Minko T; Kopecková P; Kopecek J
Time- and concentration-dependent apoptosis and necrosis induced by free and HPMA copolymer-bound doxorubicin in human ovarian carcinoma cells.
Journal of controlled release : official journal of the Controlled Release Society 2000;69(1):185-96.
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2000: Wróblewski S; Berenson M; Kopecková P; Kopecek J
Biorecognition of HPMA copolymer-lectin conjugates as an indicator of differentiation of cell-surface glycoproteins in development, maturation, and diseases of human and rodent gastrointestinal tissues.
Journal of biomedical materials research 2000;51(3):329-42.
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2000: Kopecek J; Kopecková P; Minko T; Lu Z
HPMA copolymer-anticancer drug conjugates: design, activity, and mechanism of action.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;50(1):61-81.
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2000: Minko T; Kopecková P; Kopecek J
Efficacy of the chemotherapeutic action of HPMA copolymer-bound doxorubicin in a solid tumor model of ovarian carcinoma.
International journal of cancer. Journal international du cancer 2000;86(1):108-17.
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2000: Lu Z R; Gao S Q; Kopecková P; Kopecek J
Synthesis of bioadhesive lectin-HPMA copolymer-cyclosporin conjugates.
Bioconjugate chemistry 2000;11(1):3-7.
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2000: Kunath K; Kopecková P; Minko T; Kopecek J
HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 3. The effect of free and polymer-bound adriamycin on the expression of some genes in the OVCAR-3 human ovarian carcinoma cell line.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2000;49(1):11-5.
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2000: Hart P R; Kopecková P; Omelyanenko V; Enioutina E; Kopecek J
HPMA copolymer-modified avidin: immune response.
Journal of biomaterials science. Polymer edition 2000;11(1):1-12.
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1999: Lu Z R; Kopecková P; Kopecek J
Polymerizable Fab' antibody fragments for targeting of anticancer drugs.
Nature biotechnology 1999;17(11):1101-4.
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1999: Spikes J D; Shen H R; Kopecková P; Kopecek J
Photodynamic crosslinking of proteins. III. Kinetics of the FMN- and rose bengal-sensitized photooxidation and intermolecular crosslinking of model tyrosine-containing N-(2-hydroxypropyl)methacrylamide copolymers.
Photochemistry and photobiology 1999;70(2):130-7.
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1999: Dvorák M; Kopecková P; Kopecek J
High-molecular weight HPMA copolymer-adriamycin conjugates.
Journal of controlled release : official journal of the Controlled Release Society 1999;60(2-3):321-32.
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1999: Omelyanenko V; Kopecková P; Prakash R K; Ebert C D; Kopecek J
Biorecognition of HPMA copolymer-adriamycin conjugates by lymphocytes mediated by synthetic receptor binding epitopes.
Pharmaceutical research 1999;16(7):1010-9.
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1999: Minko T; Kopecková P; Kopecek J
Comparison of the anticancer effect of free and HPMA copolymer-bound adriamycin in human ovarian carcinoma cells.
Pharmaceutical research 1999;16(7):986-96.
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1999: Minko T; Kopecková P; Kopecek J
Chronic exposure to HPMA copolymer-bound adriamycin does not induce multidrug resistance in a human ovarian carcinoma cell line.
Journal of controlled release : official journal of the Controlled Release Society 1999;59(2):133-48.
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1999: Lu R H; Kopecková P; Kopecek J
Degradation and aggregation of human calcitonin in vitro.
Pharmaceutical research 1999;16(3):359-67.
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1998: Lu Z R; Kopecková P; Wu Z; Kopecek J
Functionalized semitelechelic poly[N-(2-hydroxypropyl)methacrylamide] for protein modification.
Bioconjugate chemistry 1998;9(6):793-804.
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1998: Minko T; Kopecková P; Pozharov V; Kopecek J
HPMA copolymer bound adriamycin overcomes MDR1 gene encoded resistance in a human ovarian carcinoma cell line.
Journal of controlled release : official journal of the Controlled Release Society 1998;54(2):223-33.
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1998: Akala E O; Kopecková P; Kopecek J
Novel pH-sensitive hydrogels with adjustable swelling kinetics.
Biomaterials 1998;19(11-12):1037-47.
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1998: Omelyanenko V; Kopecková P; Gentry C; Kopecek J
Targetable HPMA copolymer-adriamycin conjugates. Recognition, internalization, and subcellular fate.
Journal of controlled release : official journal of the Controlled Release Society 1998;53(1-3):25-37.
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1998: Omelyanenko V; Gentry C; Kopecková P; Kopecek J
HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. II. Processing in epithelial ovarian carcinoma cells in vitro.
International journal of cancer. Journal international du cancer 1998;75(4):600-8.
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1997: Ghandehari H; Kopecková P; Kopecek J
In vitro degradation of pH-sensitive hydrogels containing aromatic azo bonds.
Biomaterials 1997;18(12):861-72.
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1997: Chiu H C; Kopecková P; Deshmane S S; Kopecek J
Lysosomal degradability of poly(alpha-amino acids).
Journal of biomedical materials research 1997;34(3):381-92.
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1996: Shen H R; Spikes J D; Kopecková P; Kopecek J
Photodynamic crosslinking of proteins. II. Photocrosslinking of a model protein-ribonuclease A.
Journal of photochemistry and photobiology. B, Biology 1996;35(3):213-9.
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1996: Omelyanenko V; Kopecková P; Gentry C; Shiah J G; Kopecek J
HPMA copolymer-anticancer drug-OV-TL16 antibody conjugates. 1. influence of the method of synthesis on the binding affinity to OVCAR-3 ovarian carcinoma cells in vitro.
Journal of drug targeting 1996;3(5):357-73.
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1995: Ríhová B; Rathi R C; Kopecková P; Kopecek J
Bioadhesive polymers for oral drug delivery.
Advances in experimental medicine and biology 1995;371B():1491-4.
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1993: Chiu H C; Zalipsky S; Kopecková P; Kopecek J
Enzymatic activity of chymotrypsin and its poly(ethylene glycol) conjugates toward low and high molecular weight substrates.
Bioconjugate chemistry 1993;4(4):290-5.
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1989: Flanagan P A; Kopecková P; Kopecek J; Duncan R
Evaluation of protein-N-(2-hydroxypropyl)methacrylamide copolymer conjugates as targetable drug carriers. 1. Binding, pinocytic uptake and intracellular distribution of transferrin and anti-transferrin receptor antibody conjugates.
Biochimica et biophysica acta 1989;993(1):83-91.
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1989: O'Hare K B; Hume I C; Scarlett L; Chytrý V; Kopecková P; Kopecek J; Duncan R
Effect of galactose on interaction of N-(2-hydroxypropyl)methacrylamide copolymers with hepatoma cells in culture: preliminary application to an anticancer agent, daunomycin.
Hepatology (Baltimore, Md.) 1989;10(2):207-14.
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1988: Duncan R; Kopecková P; Strohalm J; Hume I C; Lloyd J B; Kopecek J
Anticancer agents coupled to N-(2-hydroxypropyl)methacrylamide copolymers. II. Evaluation of daunomycin conjugates in vivo against L1210 leukaemia.
British journal of cancer 1988;57(2):147-56.
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1988: Ríhová B; Kopecková P; Strohalm J; Rossmann P; Vetvicka V; Kopecek J
Antibody-directed affinity therapy applied to the immune system: in vivo effectiveness and limited toxicity of daunomycin conjugated to HPMA copolymers and targeting antibody.
Clinical immunology and immunopathology 1988;46(1):100-14.
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1987: Seymour L W; Duncan R; Kopecková P; Kopecek J
Daunomycin- and adriamycin-N-(2-hydroxypropyl)methacrylamide copolymer conjugates; toxicity reduction by improved drug-delivery.
Cancer treatment reviews 1987;14(3-4):319-27.
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