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Jan Koper

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L Manenschijn; G M E E Peeters; L Schaap; S van der Pas; Jan W Koper; Paul Lips; Natasja M van Schoor; E F C van Rossum
High long-term cortisol levels, measured in scalp hair, are associated with a history of cardiovascular disease.
Laura Manenschijn; Annet T Spijker; Erik J Giltay; Judith Haffmans; Erik Hoencamp; Andrea M Jetten; Jan W Koper; Elisabeth F C van Rossum
Long-term cortisol in bipolar disorder: associations with age of onset and psychiatric co-morbidity.
L Manenschijn; E L T van den Akker; L J M de Heide; Frank de Jong; Richard A Feelders; E A M Geerdink; Jan W Koper; E F C van Rossum
A novel tool in the diagnosis and follow-up of (cyclic) Cushing's syndrome: measurement of long-term cortisol in scalp hair.

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2013: L Manenschijn; G M E E Peeters; L Schaap; S van der Pas; Jan W Koper; Paul Lips; Natasja M van Schoor; E F C van Rossum
High long-term cortisol levels, measured in scalp hair, are associated with a history of cardiovascular disease.
The Journal of clinical endocrinology and metabolism 2013;98(5):2078-83.
2012: Laura Manenschijn; Annet T Spijker; Erik J Giltay; Judith Haffmans; Erik Hoencamp; Andrea M Jetten; Jan W Koper; Elisabeth F C van Rossum
Long-term cortisol in bipolar disorder: associations with age of onset and psychiatric co-morbidity.
Psychoneuroendocrinology 2012;37(12):1960-8.
2012: L Manenschijn; E L T van den Akker; L J M de Heide; Frank de Jong; Richard A Feelders; E A M Geerdink; Jan W Koper; E F C van Rossum
A novel tool in the diagnosis and follow-up of (cyclic) Cushing's syndrome: measurement of long-term cortisol in scalp hair.
The Journal of clinical endocrinology and metabolism 2012;97(10):E1836-43.
2012: M J H J Dekker; Albert Hofman; Jan W Koper; Maris Kuningas; H J Luijendijk; P M Stewart; Henning Tiemeier; Frank de Jong; S W J Lamberts
The effect of common genetic variation in 11β-hydroxysteroid dehydrogenase type 1 on hypothalamic-pituitary-adrenal axis activity and incident depression.
The Journal of clinical endocrinology and metabolism 2012;97(2):E233-7.
2011: Laura Manenschijn; Rulanda G P M van Kruysbergen; Frank H de Jong; Jan W Koper; Elisabeth F C van Rossum
Shift work at young age is associated with elevated long-term cortisol levels and body mass index.
The Journal of clinical endocrinology and metabolism 2011;96(11):E1862-5.
2011: Laura Manenschijn; Jan W Koper; Steven W J Lamberts; Elisabeth F C van Rossum
Evaluation of a method to measure long term cortisol levels.
Steroids 2011;76(10-11):1032-6.
2010: L Manenschijn; E L T van den Akker; W A Ester; R W J Leunissen; R H Willemsen; Elisabeth F C van Rossum; Jan W Koper; S W J Lamberts; Anita C S Hokken-Koelega
Glucocorticoid receptor gene haplotypes are not associated with birth anthropometry, blood pressure, glucose and insulin concentrations, and body composition in subjects born small for gestational age.
European journal of endocrinology / European Federation of Endocrine Societies 2010;163(6):911-8.
2010: Manon J M van Oosten; R J E M Dolhain; Jan W Koper; Elisabeth F C van Rossum; Marieke Emonts; Khik H Han; Jacques M G W Wouters; J M W Hazes; Steven W J Lamberts; Richard A Feelders
Polymorphisms in the glucocorticoid receptor gene that modulate glucocorticoid sensitivity are associated with rheumatoid arthritis.
Arthritis research & therapy 2010;12(4):R159.
2010: Miranda J J Geelhoed; Eric A P Steegers; Jan W Koper; Elisabeth F C van Rossum; Henriette A Moll; Hein Raat; Henning Tiemeier; Albert Hofman; Vincent W V Jaddoe
Glucocorticoid receptor gene polymorphisms do not affect growth in fetal and early postnatal life. The Generation R Study.
BMC medical genetics 2010;11():39.
2010: Robert Kumsta; Sonja Entringer; Jan W Koper; Elisabeth F C van Rossum; Dirk H Hellhammer; Stefan Wüst
Working memory performance is associated with common glucocorticoid receptor gene polymorphisms.
Neuropsychobiology 2010;61(1):49-56.
2009: Paul G Voorhoeve; Erica L T van den Akker; Elisabeth F C van Rossum; Jan W Koper; Willem van Mechelen; Steven W J Lamberts; Henriette A Delemarre-Van De Waal
Glucocorticoid receptor gene variant is associated with increased body fatness in youngsters.
Clinical endocrinology 2009;71(4):518-23.
2009: Erica L T van den Akker; Jan W Koper; Koen F M Joosten; Frank de Jong; Jan A Hazelzet; Steven W J Lamberts; Anita C S Hokken-Koelega
Glucocorticoid receptor mRNA levels are selectively decreased in neutrophils of children with sepsis.
Intensive care medicine 2009;35(7):1247-54.
2009: R P Peeters; A Hagendorf; I Vanhorebeek; Theo J Visser; Willem Klootwijk; D Mesotten; Pieter J Wouters; Jan W Koper; Frank de Jong; Richard A Feelders; S W J Lamberts; Greet Van den Berghe
Tissue mRNA expression of the glucocorticoid receptor and its splice variants in fatal critical illness.
Clinical endocrinology 2009;71(1):145-53.
2009: Robert Kumsta; Dirk Moser; Fabian Streit; Jan W Koper; Jobst Meyer; Stefan Wüst
Characterization of a glucocorticoid receptor gene (GR, NR3C1) promoter polymorphism reveals functionality and extends a haplotype with putative clinical relevance.
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics 2009;150B(4):476-82.
2009: Marieke J H J Dekker; Erica L T van den Akker; Jan W Koper; Laura Manenschijn; Karin Geleijns; Liselotte Ruts; Wouter Van Rijs; Anne P Tio-Gillen; Pieter A Van Doorn; Steven W J Lamberts; Bart C Jacobs
Effect of glucocorticoid receptor gene polymorphisms in Guillain-Barré syndrome.
Journal of the peripheral nervous system : JPNS 2009;14(2):75-83.
2009: Lisa van Winsen; Laura Manenschijn; Elisabeth F C van Rossum; J Bart A Crusius; Bart A Crusius; Jan W Koper; Chris H Polman; Bernard M J Uitdehaag
A glucocorticoid receptor gene haplotype (TthIII1/ER22/23EK/9beta) is associated with a more aggressive disease course in multiple sclerosis.
The Journal of clinical endocrinology and metabolism 2009;94(6):2110-4.
2008: M J H J Dekker; Jan W Koper; Maarten O van Aken; H A P Pols; Albert Hofman; Frank de Jong; C Kirschbaum; J C M Witteman; S W J Lamberts; Henning Tiemeier
Salivary cortisol is related to atherosclerosis of carotid arteries.
The Journal of clinical endocrinology and metabolism 2008;93(10):3741-7.
2008: Robert Kumsta; Sonja Entringer; Jan W Koper; Elisabeth F C van Rossum; Dirk H Hellhammer; Stefan Wüst
Glucocorticoid receptor gene polymorphisms and glucocorticoid sensitivity of subdermal blood vessels and leukocytes.
Biological psychology 2008;79(2):179-84.
2008: Erica L T van den Akker; Carla C Baan; Bart van den Berg; Henk Russcher; Koen F M Joosten; Anita C S Hokken-Koelega; Steven W J Lamberts; Jan W Koper
Ficoll-separated mononuclear cells from sepsis patients are contaminated with granulocytes.
Intensive care medicine 2008;34(5):912-6.
2008: Elisabeth F C van Rossum; Frank de Jong; Jan W Koper; André G Uitterlinden; Niels D Prins; Ewoud J van Dijk; Peter J Koudstaal; Albert Hofman; Frank H de Jong; Steven W J Lamberts; Monique Breteler
Glucocorticoid receptor variant and risk of dementia and white matter lesions.
Neurobiology of aging 2008;29(5):716-23.
2008: Erica L T van den Akker; Jan W Koper; Elisabeth F C van Rossum; Marieke J H Dekker; Henk Russcher; Frank de Jong; André G Uitterlinden; Albert Hofman; Huibert A Pols; Jacqueline C M Witteman; Steven W J Lamberts
Glucocorticoid receptor gene and risk of cardiovascular disease.
Archives of internal medicine 2008;168(1):33-9.
2007: Rosemarie Felder-Puig; Christiane Scherzer; Michaela Baumgartner; Magdalena Ortner; Claudia Aschenbrenner; Christian Bieglmayer; Till Voigtländer; E Renate Panzer-Grümayer; Wim J E Tissing; Jan W Koper; Karl Steinberger; Christian Nasel; Helmut Gadner; Reinhard Topf; Michael Dworzak
Glucocorticoids in the treatment of children with acute lymphoblastic leukemia and hodgkin's disease: a pilot study on the adverse psychological reactions and possible associations with neurobiological, endocrine, and genetic markers.
Clinical cancer research : an official journal of the American Association for Cancer Research 2007;13(23):7093-100.
2007: Robert Kumsta; Sonja Entringer; Jan W Koper; Elisabeth F C van Rossum; Dirk H Hellhammer; Stefan Wüst
Sex specific associations between common glucocorticoid receptor gene variants and hypothalamus-pituitary-adrenal axis responses to psychosocial stress.
Biological psychiatry 2007;62(8):863-9.
2007: Lisa van Winsen; Tineke Van Veen; Elisabeth F C van Rossum; Jan W Koper; Frederik Barkhof; Chris H Polman; Bernard Uitdehaag
Glucocorticoid receptor gene polymorphisms associated with more aggressive disease phenotype in MS.
Journal of neuroimmunology 2007;186(1-2):150-5.
2007: Henk Russcher; Virgil A S H Dalm; Frank de Jong; Albert O Brinkmann; Leo J Hofland; Steven W J Lamberts; Jan W Koper
Associations between promoter usage and alternative splicing of the glucocorticoid receptor gene.
Journal of molecular endocrinology 2007;38(1-2):91-8.
2007: pauline smit; Marieke J H J Dekker; Frank de Jong; Annewieke W van den Beld; Jan W Koper; Huibert A P Pols; Albert O Brinkmann; Frank H de Jong; Monique Breteler; Steven W J Lamberts
Lack of Association of the 11beta-hydroxysteroid dehydrogenase type 1 gene 83,557insA and hexose-6-phosphate dehydrogenase gene R453Q polymorphisms with body composition, adrenal androgen production, blood pressure, glucose metabolism, and dementia.
The Journal of clinical endocrinology and metabolism 2007;92(1):359-62.
2006: Jantien P Brouwer; Bente C Appelhof; Elisabeth F C van Rossum; Jan W Koper; Eric Fliers; Jochanan Huyser; Aart H Schene; Jan G P Tijssen; Richard van Dyck; Steven W J Lamberts; Wilmar M Wiersinga; Witte J G Hoogendijk
Prediction of treatment response by HPA-axis and glucocorticoid receptor polymorphisms in major depression.
Psychoneuroendocrinology 2006;31(10):1154-63.
2006: Erica L T van den Akker; Jan Nouwen; Damian C Melles; Elisabeth F C van Rossum; Jan W Koper; André G Uitterlinden; Albert Hofman; Henri A Verbrugh; Huibert A P Pols; Steven W J Lamberts; Alex Van Belkum
Staphylococcus aureus nasal carriage is associated with glucocorticoid receptor gene polymorphisms.
The Journal of infectious diseases 2006;194(6):814-8.
2006: Erica L T van den Akker; Henk Russcher; Elisabeth F C van Rossum; Albert O Brinkmann; Frank de Jong; Anita Hokken; Huibert A P Pols; Jan W Koper; Steven W J Lamberts
Glucocorticoid receptor polymorphism affects transrepression but not transactivation.
The Journal of clinical endocrinology and metabolism 2006;91(7):2800-3.
2006: Elisabeth F C van Rossum; Elisabeth B Binder; Matthias Majer; Jan W Koper; Marcus Ising; Sieglinde Modell; Daria Salyakina; Steven W J Lamberts; Florian Holsboer
Polymorphisms of the glucocorticoid receptor gene and major depression.
Biological psychiatry 2006;59(8):681-8.
2006: Paul G Voorhoeve; Elisabeth F C van Rossum; Saskia te Velde; Jan W Koper; Han CG Kemper; Steven W J Lamberts; Henriette A Delemarre-van de Waal
Association between an IGF-I gene polymorphism and body fatness: differences between generations.
European journal of endocrinology / European Federation of Endocrine Societies 2006;154(3):379-88.
2006: Henk Russcher; pauline smit; Elisabeth F C van Rossum; Erica L T van den Akker; Albert O Brinkmann; Loek J M de Heide; Frank de Jong; Jan W Koper; Steven W J Lamberts
Strategies for the characterization of disorders in cortisol sensitivity.
The Journal of clinical endocrinology and metabolism 2006;91(2):694-701.
2005: Antje Hagendorf; Jan W Koper; Frank de Jong; Albert O Brinkmann; Steven W J Lamberts; Richard A Feelders
Expression of the human glucocorticoid receptor splice variants alpha, beta, and P in peripheral blood mononuclear leukocytes in healthy controls and in patients with hyper- and hypocortisolism.
The Journal of clinical endocrinology and metabolism 2005;90(11):6237-43.
2005: Lisa L M van Winsen; Tineke Van Veen; Elisabeth F C van Rossum; Chris H Polman; Timo K van den Berg; Jan W Koper; Bernard Uitdehaag
The impact of glucocorticoid receptor gene polymorphisms on glucocorticoid sensitivity is outweighted in patients with multiple sclerosis.
Journal of neuroimmunology 2005;167(1-2):150-6.
2005: Henk Russcher; pauline smit; Erica L T van den Akker; Elisabeth F C van Rossum; Albert O Brinkmann; Frank de Jong; Steven W J Lamberts; Jan W Koper
Two polymorphisms in the glucocorticoid receptor gene directly affect glucocorticoid-regulated gene expression.
The Journal of clinical endocrinology and metabolism 2005;90(10):5804-10.
2005: Wim J E Tissing; Melchior Lauten; Jules P P Meijerink; Monique L den Boer; Jan W Koper; Pieter Sonneveld; Rob Pieters
Expression of the glucocorticoid receptor and its isoforms in relation to glucocorticoid resistance in childhood acute lymphocytic leukemia.
Haematologica 2005;90(9):1279-81.
2005: pauline smit; Ron van Schaik; Marloes van der Werf; Annewieke W van den Beld; Jan W Koper; Jan Lindemans; Huibert A P Pols; Albert O Brinkmann; Frank de Jong; Steven W J Lamberts
A common polymorphism in the CYP3A7 gene is associated with a nearly 50% reduction in serum dehydroepiandrosterone sulfate levels.
The Journal of clinical endocrinology and metabolism 2005;90(9):5313-6.
2005: Wim J E Tissing; Jules P P Meijerink; Monique L den Boer; Bas Brinkhof; Elisabeth F C van Rossum; Elisabeth R van Wering; Jan W Koper; Pieter Sonneveld; Rob Pieters
Genetic variations in the glucocorticoid receptor gene are not related to glucocorticoid resistance in childhood acute lymphoblastic leukemia.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(16):6050-6.
2005: Henk Russcher; Elisabeth F C van Rossum; Frank de Jong; Albert O Brinkmann; Steven W J Lamberts; Jan W Koper
Increased expression of the glucocorticoid receptor-A translational isoform as a result of the ER22/23EK polymorphism.
Molecular endocrinology (Baltimore, Md.) 2005;19(7):1687-96.
2005: pauline smit; Henk Russcher; Frank de Jong; Albert O Brinkmann; Steven W J Lamberts; Jan W Koper
Differential regulation of synthetic glucocorticoids on gene expression levels of glucocorticoid-induced leucine zipper and interleukin-2.
The Journal of clinical endocrinology and metabolism 2005;90(5):2994-3000.
2005: Stefan Wüst; Ilona Yim; Elisabeth F C van Rossum; Jan W Koper; Dirk H Hellhammer
Habituation of cortisol responses to repeated psychosocial stress-further characterization and impact of genetic factors.
Psychoneuroendocrinology 2005;30(2):199-211.
2004: Stefan Wüst; Ilona Yim; Elisabeth F C van Rossum; Jan W Koper; Robert Kumsta; Sonja Entringer; Dirk H Hellhammer
A psychobiological perspective on genetic determinants of hypothalamus-pituitary-adrenal axis activity.
Annals of the New York Academy of Sciences 2004;1032():52-62.
2004: Elisabeth F C van Rossum; Petronella H M Roks; Frank de Jong; Albert O Brinkmann; Huibert A P Pols; Jan W Koper; Steven W J Lamberts
Characterization of a promoter polymorphism in the glucocorticoid receptor gene and its relationship to three other polymorphisms.
Clinical endocrinology 2004;61(5):573-81.
2004: Pieter C J ter Borg; A Hagendorf; Henk R van Buuren; Jan W Koper; Steven W J Lamberts
A pilot study exploring the role of glucocorticoid receptor variants in primary biliary cirrhosis and primary sclerosing cholangitis.
The Netherlands journal of medicine 2004;62(9):326-31.
2004: Elisabeth F C van Rossum; Paul G Voorhoeve; Saskia te Velde; Jan W Koper; Henriette A Delemarre-Van De Waal; Han CG Kemper; Steven W J Lamberts
The ER22/23EK polymorphism in the glucocorticoid receptor gene is associated with a beneficial body composition and muscle strength in young adults.
The Journal of clinical endocrinology and metabolism 2004;89(8):4004-9.
2004: Elisabeth F C van Rossum; Richard A Feelders; Annewieke W van den Beld; André G Uitterlinden; Joop A M J L Janssen; Wietske Ester; Albert O Brinkmann; Diederick Grobbee; Frank de Jong; Huibert A P Pols; Jan W Koper; Steven W J Lamberts
Association of the ER22/23EK polymorphism in the glucocorticoid receptor gene with survival and C-reactive protein levels in elderly men.
The American journal of medicine 2004;117(3):158-62.
2004: Stefan Wüst; Elisabeth F C van Rossum; Ilona Yim; Jan W Koper; Robert Kumsta; Dirk H Hellhammer
Common polymorphisms in the glucocorticoid receptor gene are associated with adrenocortical responses to psychosocial stress.
The Journal of clinical endocrinology and metabolism 2004;89(2):565-73.
2003: Elisabeth F C van Rossum; Jan W Koper; Annewieke W van den Beld; André G Uitterlinden; Pascal P Arp; Wietske Ester; Joop A M J L Janssen; Albert O Brinkmann; Frank de Jong; Diederick Grobbee; Huibert A P Pols; Steven W J Lamberts
Identification of the BclI polymorphism in the glucocorticoid receptor gene: association with sensitivity to glucocorticoids in vivo and body mass index.
Clinical endocrinology 2003;59(5):585-92.
2003: Anna Maria di Blasio; Elisabeth F C van Rossum; Sabrina Maestrini; Maria Elisa Berselli; Mariantonella Tagliaferri; Francesca Podestà; Jan W Koper; Antonio Liuzzi; Steven W J Lamberts
The relation between two polymorphisms in the glucocorticoid receptor gene and body mass index, blood pressure and cholesterol in obese patients.
Clinical endocrinology 2003;59(1):68-74.
2002: Erica L T van den Akker; Jan W Koper; Annemie L M Boehmer; Axel P N Themmen; Miriam Verhoef-Post; Marianna A Timmerman; Barto J Otten; Stenvert L S Drop; Frank de Jong
Differential inhibition of 17alpha-hydroxylase and 17,20-lyase activities by three novel missense CYP17 mutations identified in patients with P450c17 deficiency.
The Journal of clinical endocrinology and metabolism 2002;87(12):5714-21.
2002: Elisabeth F C van Rossum; Jan W Koper; Nannette A T M Huizenga; André G Uitterlinden; Joop A M J L Janssen; Albert O Brinkmann; Diederick Grobbee; Frank de Jong; Cornelia M van Duyn; Huibert A P Pols; Steven W J Lamberts
A polymorphism in the glucocorticoid receptor gene, which decreases sensitivity to glucocorticoids in vivo, is associated with low insulin and cholesterol levels.
Diabetes 2002;51(10):3128-34.
2001: P de Lange; Christine M Segeren; Jan W Koper; E Wiemer; Pieter Sonneveld; Albert O Brinkmann; A White; I J Brogan; Frank de Jong; Steven W J Lamberts
Expression in hematological malignancies of a glucocorticoid receptor splice variant that augments glucocorticoid receptor-mediated effects in transfected cells.
Cancer research 2001;61(10):3937-41.
2001: Bernard Uitdehaag; Karin Hoekstra; Jan W Koper; Chris H Polman; Christine D Dijkstra
IFN-beta1b augments glucocorticoid-induced suppression of tumor necrosis factor-alpha production by increasing the number of glucocorticoid receptors on a human monocytic cell line.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2001;21(3):133-5.
2000: Erwin van der Harst; Hajo A Bruining; H Jaap Bonjer; Frieda van der Ham; Winand N M Dinjens; Steven W J Lamberts; Wouter W de Herder; Jan W Koper; Theo Stijnen; C Proye; M Lecomte-Houcke; Fred T Bosman; Ronald R de Krijger
Proliferative index in phaeochromocytomas: does it predict the occurrence of metastases?
The Journal of pathology 2000;191(2):175-80.
2000: Jan W Koper; Steven W J Lamberts
Sporadic endocrine tumours and their relationship to the hereditary endocrine neoplasia syndromes.
European journal of clinical investigation 2000;30(6):493-500.
2000: Nannette A T M Huizenga; P de Lange; Jan W Koper; Wouter W de Herder; R Abs; J H Kasteren; Frank de Jong; Steven W J Lamberts
Five patients with biochemical and/or clinical generalized glucocorticoid resistance without alterations in the glucocorticoid receptor gene.
The Journal of clinical endocrinology and metabolism 2000;85(5):2076-81.
2000: Nannette A T M Huizenga; Wouter W de Herder; Jan W Koper; P de Lange; A J v D Lely; Albert O Brinkmann; Frank de Jong; Steven W J Lamberts
Decreased ligand affinity rather than glucocorticoid receptor down-regulation in patients with endogenous Cushing's syndrome.
European journal of endocrinology / European Federation of Endocrine Societies 2000;142(5):472-6.
1999: P de Lange; Jan W Koper; Albert O Brinkmann; Frank de Jong; Steven W J Lamberts
Natural variants of the beta isoform of the human glucocorticoid receptor do not alter sensitivity to glucocorticoids.
Molecular and cellular endocrinology 1999;153(1-2):163-8.
1999: Ronald R de Krijger; Erwin van der Harst; Frieda van der Ham; Theo Stijnen; Winand N M Dinjens; Jan W Koper; Hajo A Bruining; Steven W J Lamberts; Fred T Bosman
Prognostic value of p53, bcl-2, and c-erbB-2 protein expression in phaeochromocytomas.
The Journal of pathology 1999;188(1):51-5.
1999: J Jansen; Bernard Uitdehaag; Jan W Koper; Timo K van den Berg
Glucocorticoid receptor ligand binding in monocytic cells using a microplate assay.
Pathobiology : journal of immunopathology, molecular and cellular biology 1999;67(5-6):262-4.
1998: Erwin van der Harst; Ronald R de Krijger; Hajo A Bruining; S W Lamberts; H Jaap Bonjer; W N Dinjes; C Proye; Jan W Koper; Fred T Bosman; J Roth; Philipp U Heitz; Paul Komminoth
Prognostic value of RET proto-oncogene point mutations in malignant and benign, sporadic phaeochromocytomas.
International journal of cancer. Journal international du cancer 1998;79(5):537-40.
1998: Joop A M J L Janssen; Jan W Koper; RP Stolk; P Englaro; André G Uitterlinden; Q Huang; Johannes P T M van Leeuwen; Werner F Blum; A M Attanasio; Huibert A P Pols; Diederick Grobbee; Frank de Jong; Steven W J Lamberts
Lack of associations between serum leptin, a polymorphism in the gene for the beta 3-adrenergic receptor and glucose tolerance in the Dutch population.
Clinical endocrinology 1998;49(2):229-34.
1998: Erwin van der Harst; Ronald R de Krijger; Winand N M Dinjens; L E Weeks; H Jaap Bonjer; Hajo A Bruining; Steven W J Lamberts; Jan W Koper
Germline mutations in the vhl gene in patients presenting with phaeochromocytomas.
International journal of cancer. Journal international du cancer 1998;77(3):337-40.
1998: Nannette A T M Huizenga; P de Lange; Jan W Koper; R N Clayton; W E Farrell; Aart Jan Van der Lely; Albert O Brinkmann; Frank de Jong; Steven W J Lamberts
Human adrenocorticotropin-secreting pituitary adenomas show frequent loss of heterozygosity at the glucocorticoid receptor gene locus.
The Journal of clinical endocrinology and metabolism 1998;83(3):917-21.
1998: Nannette A T M Huizenga; Jan W Koper; P de Lange; Huibert A P Pols; RP Stolk; H Burger; Diederick Grobbee; Albert O Brinkmann; Frank de Jong; Steven W J Lamberts
A polymorphism in the glucocorticoid receptor gene may be associated with and increased sensitivity to glucocorticoids in vivo.
The Journal of clinical endocrinology and metabolism 1998;83(1):144-51.
1998: Nannette A T M Huizenga; Jan W Koper; P de Lange; Huibert A P Pols; RP Stolk; Diederick Grobbee; Frank de Jong; Steven W J Lamberts
Interperson variability but intraperson stability of baseline plasma cortisol concentrations, and its relation to feedback sensitivity of the hypothalamo-pituitary-adrenal axis to a low dose of dexamethasone in elderly individuals.
The Journal of clinical endocrinology and metabolism 1998;83(1):47-54.
1997: P de Lange; Jan W Koper; Nannette A T M Huizenga; Albert O Brinkmann; Frank de Jong; Michael Karl; George Chrousos; Steven W J Lamberts
Differential hormone-dependent transcriptional activation and -repression by naturally occurring human glucocorticoid receptor variants.
Molecular endocrinology (Baltimore, Md.) 1997;11(8):1156-64.
1997: Jan W Koper; RP Stolk; P de Lange; Nannette A T M Huizenga; G J Molijn; Huibert A P Pols; Diederick Grobbee; Michael Karl; Frank de Jong; Albert O Brinkmann; Steven W J Lamberts
Lack of association between five polymorphisms in the human glucocorticoid receptor gene and glucocorticoid resistance.
Human genetics 1997;99(5):663-8.
1997: Jan W Koper; G J Molijn; CJ Van Uffelen; E Stigter; Steven W J Lamberts
Antiprogestins and iatrogenic glucocorticoid resistance.
Life sciences 1997;60(9):617-24.
1996: Steven W J Lamberts; A T Huizenga; P de Lange; Frank de Jong; Jan W Koper
Clinical aspects of glucocorticoid sensitivity.
Steroids 1996;61(4):157-60.
1996: Wouter A P Breeman; M P VanHagen; H A Visser-Wisselaar; ME van der Pluijm; Jan W Koper; B Setyono-Han; Willem H Bakker; Dik J Kwekkeboom; M P Hazenberg; Steven W J Lamberts; Theo J Visser; Eric P Krenning
In vitro and in vivo studies of substance P receptor expression in rats with the new analog [indium-111-DTPA-Arg1]substance P.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1996;37(1):108-17.
1995: G J Molijn; Jan W Koper; C J van Uffelen; Frank de Jong; Albert O Brinkmann; Hajo A Bruining; Steven W J Lamberts
Temperature-induced down-regulation of the glucocorticoid receptor in peripheral blood mononuclear leucocyte in patients with sepsis or septic shock.
Clinical endocrinology 1995;43(2):197-203.
1995: G J Molijn; J J Spek; J C van Uffelen; Frank de Jong; Albert O Brinkmann; Hajo A Bruining; Steven W J Lamberts; Jan W Koper
Differential adaptation of glucocorticoid sensitivity of peripheral blood mononuclear leukocytes in patients with sepsis or septic shock.
The Journal of clinical endocrinology and metabolism 1995;80(6):1799-803.
1995: R H Lekanne Deprez; P H Riegman; Ellen van Drunen; U L Warringa; N A Groen; S Z Stefanko; Jan W Koper; Cees J J Avezaat; P G Mulder; Ellen C Zwarthoff
Cytogenetic, molecular genetic and pathological analyses in 126 meningiomas.
Journal of neuropathology and experimental neurology 1995;54(2):224-35.
1995: Steven W J Lamberts; Wouter W de Herder; Peter M Van Koetsveld; Jan W Koper; A J van der Lely; H A Visser-Wisselaar; Leo Hofland
Somatostatin receptors: clinical implications for endocrinology and oncology.
Ciba Foundation symposium 1995;190():222-36; discussion 236-9.
1994: Jan W Koper; Steven W J Lamberts
Meningiomas, epidermal growth factor and progesterone.
Human reproduction (Oxford, England) 1994;9 Suppl 1():190-4.
1994: R H Lekanne Deprez; A B Bianchi; N A Groen; BR Seizinger; Anne Hagemeijer; Ellen van Drunen; Dirk Bootsma; Jan W Koper; Cees J J Avezaat; N Kley
Frequent NF2 gene transcript mutations in sporadic meningiomas and vestibular schwannomas.
American journal of human genetics 1994;54(6):1022-9.
1994: R H LeKanne Deprez; N A Groen; D Louz; Anne Hagemeijer; Ellen van Drunen; Jan W Koper; Cees J J Avezaat; Dirk Bootsma; Theo Van der Kwast; Ellen C Zwarthoff
Constitutional DNA-level aberrations in chromosome 22 in a patient with multiple meningiomas.
Genes, chromosomes & cancer 1994;9(2):124-8.
1992: Steven W J Lamberts; Jan W Koper; Frank de Jong
Familial and iatrogenic cortisol receptor resistance.
The Journal of steroid biochemistry and molecular biology 1992;43(5):385-8.
1992: Steven W J Lamberts; Jan W Koper; J C Reubi; Eric P Krenning
Endocrine aspects of the diagnosis and treatment of primary brain tumours.
Clinical endocrinology 1992;37(1):1-10.
1992: Steven W J Lamberts; H L Tanghe; Cees J J Avezaat; R Braakman; R Wijngaarde; Jan W Koper; H de Jong
Mifepristone (RU 486) treatment of meningiomas.
Journal of neurology, neurosurgery, and psychiatry 1992;55(6):486-90.
1992: Jan W Koper; R Markstein; C Kohler; Dik J Kwekkeboom; Cees J J Avezaat; Steven W J Lamberts; J C Reubi
Somatostatin inhibits the activity of adenylate cyclase in cultured human meningioma cells and stimulates their growth.
The Journal of clinical endocrinology and metabolism 1992;74(3):543-7.
1992: Steven W J Lamberts; Jan W Koper; P Biemond; F H den Holder; Frank de Jong
Cortisol receptor resistance: the variability of its clinical presentation and response to treatment.
The Journal of clinical endocrinology and metabolism 1992;74(2):313-21.
1991: Steven W J Lamberts; Jan W Koper; Frank de Jong
The endocrine effects of long-term treatment with mifepristone (RU 486).
The Journal of clinical endocrinology and metabolism 1991;73(1):187-91.
1991: Willem H Bakker; Eric P Krenning; Wouter A P Breeman; Peter P M Kooij; J C Reubi; Jan W Koper; Marion De Jong; J S Laméris; Theo J Visser; Steven W J Lamberts
In vivo use of a radioiodinated somatostatin analogue: dynamics, metabolism, and binding to somatostatin receptor-positive tumors in man.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1991;32(6):1184-9.
1991: R H Lekanne Deprez; N A Groen; N A van Biezen; Anne Hagemeijer; Ellen van Drunen; Jan W Koper; Cees J J Avezaat; Dirk Bootsma; Ellen C Zwarthoff
A t(4;22) in a meningioma points to the localization of a putative tumor-suppressor gene.
American journal of human genetics 1991;48(4):783-90.
1991: Jan W Koper; Ellen C Zwarthoff; A Hagemeijer; R Braakman; Cees J J Avezaat; M Bergström; Steven W J Lamberts
Inhibition of the growth of cultured human meningioma cells by recombinant interferon-alpha.
European journal of cancer (Oxford, England : 1990) 1991;27(4):416-9.
1991: T W Huisman; H L Tanghe; Jan W Koper; Jean Claude Reubi; J A Foekens; Cees J J Avezaat; R Braakman; Steven W J Lamberts
Progesterone, oestradiol, somatostatin and epidermal growth factor receptors on human meningiomas and their CT characteristics.
European journal of cancer (Oxford, England : 1990) 1991;27(11):1453-7.
1991: Willem H Bakker; Rainer Albert; Christian Bruns; Wouter A P Breeman; Leo Hofland; P Marbach; Janos Pless; D Pralet; Barbara Stolz; Jan W Koper
[111In-DTPA-D-Phe1]-octreotide, a potential radiopharmaceutical for imaging of somatostatin receptor-positive tumors: synthesis, radiolabeling and in vitro validation.
Life sciences 1991;49(22):1583-91.
1990: Jan W Koper; Leo Hofland; Peter M Van Koetsveld; F den Holder; Steven W J Lamberts
Desensitization and resensitization of rat pituitary tumor cells in long-term culture to the effects of the somatostatin analogue SMS 201-995 on cell growth and prolactin secretion.
Cancer research 1990;50(19):6238-42.
1990: Willem H Bakker; Eric P Krenning; Wouter A P Breeman; Jan W Koper; Peter P M Kooij; J C Reubi; J G Klijn; Theo J Visser; R Docter; Steven W J Lamberts
Receptor scintigraphy with a radioiodinated somatostatin analogue: radiolabeling, purification, biologic activity, and in vivo application in animals.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1990;31(9):1501-9.
1990: Jan W Koper; John A Foekens; R Braakman; Steven W J Lamberts
Effects of progesterone on the response to epidermal growth factor and other growth factors in cultured human meningioma cells.
Cancer research 1990;50(9):2604-7.
1989: Steven W J Lamberts; Jan W Koper; P Biemond; F H den Holder; Frank de Jong
Familial and iatrogenic cortisol receptor resistance.
Cancer research 1989;49(8 Suppl):2217s-2219s.
1989: Eric P Krenning; Willem H Bakker; Wouter A P Breeman; Jan W Koper; Peter P M Kooij; L Ausema; J S Lameris; J C Reubi; Steven W J Lamberts
Localisation of endocrine-related tumours with radioiodinated analogue of somatostatin.
Lancet 1989;1(8632):242-4.
1987: Leo Hofland; Peter M Van Koetsveld; Jan W Koper; A den Holder; Steven W J Lamberts
Weak estrogenic activity of phenol red in the culture medium: its role in the study of the regulation of prolactin release in vitro.
Molecular and cellular endocrinology 1987;54(1):43-50.
1987: Steven W J Lamberts; Jan W Koper; J C Reubi
Potential role of somatostatin analogues in the treatment of cancer.
European journal of clinical investigation 1987;17(4):281-7.