FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Cosima Baldari

Research Profile

Physiology

Anatomy

Chemicals & Drugs

Living Beings

Mouse

Phenomena

Phosphorylation

Co-author Network

Publications

TOP 3
Maria Teresa Savino; Cristina Ulivieri; Enrico Beccastrini; Giulia De Falco; Mario M D'Elios; Giacomo Emmi; Lorenzo Emmi; Barbara Ortensi; Giuliana Pelicci; Domenico Prisco; Cosima T Baldari
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development.
Cristina Ulivieri; Cosima T Baldari
T-cell-based immunotherapy of autoimmune diseases.
Francesca Finetti; Cosima T Baldari
Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Cosima Baldari (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Maria Teresa Savino; Cristina Ulivieri; Enrico Beccastrini; Giulia De Falco; Mario M D'Elios; Giacomo Emmi; Lorenzo Emmi; Barbara Ortensi; Giuliana Pelicci; Domenico Prisco; Cosima T Baldari
The Shc family protein adaptor, Rai, acts as a negative regulator of Th17 and Th1 cell development.
Journal of leukocyte biology 2013;93(4):549-59.
2013: Cristina Ulivieri; Cosima T Baldari
T-cell-based immunotherapy of autoimmune diseases.
Expert review of vaccines 2013;12(3):297-310.
2013: Francesca Finetti; Cosima T Baldari
Compartmentalization of signaling by vesicular trafficking: a shared building design for the immune synapse and the primary cilium.
Immunological reviews 2013;251(1):97-112.
2012: Nagaja Capitani; Francesco Forconi; Federica Frezzato; Cristina Gattazzo; Orso Maria Lucherini; Enrica Migliaccio; Laura Patrussi; Piergiuseppe Pelicci; Gianpietro Semenzato; Livio Trentin; Enrica Cannizzaro; Cosima T Baldari
S1P1 expression is controlled by the pro-oxidant activity of p66Shc and is impaired in B-CLL patients with unfavorable prognosis.
Blood 2012;120(22):4391-9.
2012: Nagaja Capitani; Andrea Matucci; A Pezzicoli; Alessandra Renieri; A Troilo; Alessandra Vultaggio; Amedeo Amedei; Francesca Ariani; Cosima T Baldari; M M D' Elios
Vav1 haploinsufficiency in a common variable immunodeficiency patient with defective T-cell function.
International journal of immunopathology and pharmacology 2012;25(3):811-7.
2012: Laura Patrussi; Michela Pellegrini; Alessandra Gamberucci; Nico Giommoni; Cosima T Baldari
p66Shc-dependent apoptosis requires Lck and CamKII activity.
Apoptosis : an international journal on programmed cell death 2012;17(2):174-86.
2012: Marisa Benagiano; Alessandra Ciervo; Marina de Bernard; Amedeo Amedei; Cosima T Baldari; Sofia D'Elios; Chiara Della Bella; Mauro Ferrari; Fabiola Mancini; Fabio Munari; Silvia Rossi Paccani; Domenico Prisco; Camilla Ulivi; Mario Milco D'Elios
Chlamydophila pneumoniae phospholipase D (CpPLD) drives Th17 inflammation in human atherosclerosis.
Proceedings of the National Academy of Sciences of the United States of America 2012;109(4):1222-7.
2011: Gianluca Baldanzi; Cosima T Baldari; Valentina Bettio; Federica Chianale; Nicoletta Filigheddu; Riccardo Mesturini; Kim E Nichols; ORNELLA PAROLINI; Laura Patrussi; Andrea Pighini; Paolo E Porporato; Elena Rainero; Ignacio Rubio; Tamas Schweighoffer; Fabiola Sinigaglia; Shuping Song; Sara Traini; Wim J van Blitterswijk; Xiaoping Zhong; Andrea Graziani
SAP-mediated inhibition of diacylglycerol kinase α regulates TCR-induced diacylglycerol signaling.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(11):5941-51.
2011: Luca Cantarini; Rolando Cimaz; Cosima T Baldari; Francesca Bellisai; Maurizio Benucci; S Bombardieri; M G Brizi; A Brucato; Teresa Giani; F Iacoponi; franco laghi pasini; O M Lucherini; L Obici; G Paolazzi; Donato Rigante; Luciano Sabadini; gian domenico sebastiani; Gabriele Simonini; G Valentini; Mauro Galeazzi
Validation of a diagnostic score for the diagnosis of autoinflammatory diseases in adults.
International journal of immunopathology and pharmacology 2011;24(3):695-702.
2011: Silvia Rossi Paccani; Laura Patrussi; Marilyne Davi; Mario Milco D'Elios; Francesca Finetti; Daniel Ladant; Cosima T Baldari
The Bordetella pertussis adenylate cyclase toxin binds to T cells via LFA-1 and induces its disengagement from the immune synapse.
The Journal of experimental medicine 2011;208(6):1317-30.
2011: Silvia Rossi Paccani; Cosima T Baldari
T cell targeting by anthrax toxins: two faces of the same coin.
Toxins 2011;3(6):660-71.
2011: Silvia Rossi Paccani; Marisa Benagiano; Maria Teresa Savino; Francesca Finetti; Fiorella Tonello; Mario Milco D'Elios; Cosima T Baldari
The adenylate cyclase toxin of Bacillus anthracis is a potent promoter of T(H)17 cell development.
The Journal of allergy and clinical immunology 2011;127(6):1635-7.
2011: Cristina Ulivieri; Daniela Fanigliulo; Giulia Masi; Maria Teresa Savino; Alessandra Gamberucci; Pier Giuseppe Pelicci; Cosima T Baldari
p66Shc is a negative regulator of FcεRI-dependent signaling in mast cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(9):5095-106.
2011: John L Telford; Cosima T Baldari
Shigella targets T cells.
Cell host & microbe 2011;9(4):253-4.
2011: Francesca Finetti; Silvia Rossi Paccani; Joel Rosenbaum; Cosima T Baldari
Intraflagellar transport: a new player at the immune synapse.
Trends in immunology 2011;32(4):139-45.
2011: Laura Patrussi; Cosima T Baldari
The CXCL12/CXCR4 axis as a therapeutic target in cancer and HIV-1 infection.
Current medicinal chemistry 2011;18(4):497-512.
2010: Nagaja Capitani; Orso M Lucherini; Cosima T Baldari
Negative regulation of immunoreceptor signaling by protein adapters: Shc proteins join the club.
FEBS letters 2010;584(24):4915-22.
2010: Luca Cantarini; O M Lucherini; F Iacoponi; Rolando Cimaz; G Simonini; D Rigante; Franco Laghi Pasini; Cosima T Baldari; Pier Leopoldo Capecchi; M G Brizi; Mauro Galeazzi
Development and preliminary validation of a diagnostic score for identifying patients affected with adult-onset autoinflammatory disorders.
International journal of immunopathology and pharmacology 2010;23(4):1133-41.
2010: Nagaja Capitani; Amedeo Amedei; Silvia Rossi Paccani; Andrea Matucci; Alessandra Vultaggio; Gianfranco Del Prete; Cosima T Baldari; Mario Milco D'Elios
Impaired TH2 response in patients with Vav1-deficient common variable immunodeficiency with T-cell defects.
The Journal of allergy and clinical immunology 2010;126(3):671-5.
2010: Luca Cantarini; D Rigante; O M Lucherini; Rolando Cimaz; Franco Laghi Pasini; Cosima T Baldari; Maurizio Benucci; G Simonini; V Di Sabatino; M G Brizi; Mauro Galeazzi
Role of etanercept in the treatment of tumor necrosis factor receptor-associated periodic syndrome: personal experience and review of the literature.
International journal of immunopathology and pharmacology 2010;23(3):701-7.
2010: Claire N Stevens; Ann-Marie Simeone; Susan John; Zamal Ahmed; Orso M Lucherini; Cosima T Baldari; John E Ladbury
T-cell receptor early signalling complex activation in response to interferon-alpha receptor stimulation.
The Biochemical journal 2010;428(3):429-37.
2010: Nagaja Capitani; Orso Maria Lucherini; Elisa Sozzi; Micol Ferro; Nico Giommoni; Francesca Finetti; Giulia De Falco; Emanuele Cencini; Donatella Raspadori; Pier Giuseppe Pelicci; Francesco Lauria; Francesco Forconi; Cosima T Baldari
Impaired expression of p66Shc, a novel regulator of B-cell survival, in chronic lymphocytic leukemia.
Blood 2010;115(18):3726-36.
2010: Luca Cantarini; Orso Maria Lucherini; Cosima T Baldari; Franco Laghi Pasini; Mauro Galeazzi
Familial clustering of recurrent pericarditis may disclose tumour necrosis factor receptor-associated periodic syndrome.
Clinical and experimental rheumatology 2010;28(3):405-7.
2010: Daniela Benati; Micol Ferro; Maria Teresa Savino; Cristina Ulivieri; Ebe Schiavo; Annalisa Nuccitelli; Franco Laghi Pasini; Cosima T Baldari
Opposite effects of simvastatin on the bactericidal and inflammatory response of macrophages to opsonized S. aureus.
Journal of leukocyte biology 2010;87(3):433-42.
2010: Antonella Naldini; Emilia Morena; Annalisa Pucci; Michela Pellegrini; Cosima T Baldari; Pier Giuseppe Pelicci; Marco Presta; Dragana Vukasovic; Fabio Carraro
The adaptor protein p66Shc is a positive regulator in the angiogenic response induced by hypoxic T cells.
Journal of leukocyte biology 2010;87(3):365-9.
2010: Cosima T Baldari; Joel Rosenbaum
Intraflagellar transport: it's not just for cilia anymore.
Current opinion in cell biology 2010;22(1):75-80.
2010: Nagaja Capitani; Cosima T Baldari
The Bcl-2 family as a rational target for the treatment of B-cell chronic lymphocytic leukaemia.
Current medicinal chemistry 2010;17(9):801-11.
2009: Jean-Nicolas Tournier; Silvia Rossi Paccani; Anne Quesnel-Hellmann; Cosima T Baldari
Anthrax toxins: a weapon to systematically dismantle the host immune defenses.
Molecular aspects of medicine 2009;30(6):456-66.
2009: Cosima T Baldari; Gary A Koretzky
Lymphocyte signaling in the Tuscan hills.
Immunity 2009;31(5):692-5.
2009: Francesca Finetti; Maria Teresa Savino; Cosima T Baldari
Positive and negative regulation of antigen receptor signaling by the Shc family of protein adapters.
Immunological reviews 2009;232(1):115-34.
2009: Francesca Finetti; Silvia Rossi Paccani; Maria Giovanna Riparbelli; Emiliana Giacomello; Giuseppe Perinetti; Gregory J Pazour; Joel L Rosenbaum; Cosima T Baldari
Intraflagellar transport is required for polarized recycling of the TCR/CD3 complex to the immune synapse.
Nature cell biology 2009;11(11):1332-9.
2009: Luca Cantarini; O M Lucherini; Rolando Cimaz; Cosima T Baldari; Francesca Bellisai; S Rossi Paccani; Franco Laghi Pasini; Pier Leopoldo Capecchi; gian domenico sebastiani; Mauro Galeazzi
Idiopathic recurrent pericarditis refractory to colchicine treatment can reveal tumor necrosis factor receptor-associated periodic syndrome.
International journal of immunopathology and pharmacology 2009;22(4):1051-8.
2009: Luca Cantarini; O M Lucherini; Mauro Galeazzi; F Fanti; G Simonini; Cosima T Baldari; Franco Laghi Pasini; Maurizio de Martino; Rolando Cimaz
Tumour necrosis factor receptor-associated periodic syndrome caused by a rare mutation in the TNFRSF1A gene, and with excellent response to etanercept treatment.
Clinical and experimental rheumatology 2009;27(5):890-1.
2009: T Tiepolo; Alessia Angelin; E Palma; Patrizia Sabatelli; Luciano Merlini; L Nicolosi; F Finetti; Paola Braghetta; G Vuagniaux; J-M Dumont; Cosima T Baldari; Paolo Bonaldo; Paolo Bernardi
The cyclophilin inhibitor Debio 025 normalizes mitochondrial function, muscle apoptosis and ultrastructural defects in Col6a1-/- myopathic mice.
British journal of pharmacology 2009;157(6):1045-52.
2009: Michela Pellegrini; Cosima T Baldari
Apoptosis and oxidative stress-related diseases: the p66Shc connection.
Current molecular medicine 2009;9(3):392-8.
2009: Silvia Rossi Paccani; Marisa Benagiano; Nagaja Capitani; Irene Zornetta; Daniel Ladant; Cesare Montecucco; Mario Milco D'Elios; Cosima T Baldari
The adenylate cyclase toxins of Bacillus anthracis and Bordetella pertussis promote Th2 cell development by shaping T cell antigen receptor signaling.
PLoS pathogens 2009;5(3):e1000325.
2009: Maria Teresa Savino; Barbara Ortensi; Micol Ferro; Cristina Ulivieri; Daniela Fanigliulo; Eugenio Paccagnini; Stefano Lazzi; Daniela Osti; Giuliana Pelicci; Cosima T Baldari
Rai acts as a negative regulator of autoimmunity by inhibiting antigen receptor signaling and lymphocyte activation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(1):301-8.
2008: Cosima T Baldari
DNA methylation and TLR9 ligands: not only a matter of semantics.
Immunology letters 2008;121(1):84-5.
2008: Gaia Codolo; Amedeo Amedei; Allen C Steere; Elena Papinutto; Andrea Cappon; Alessandra Polenghi; Marisa Benagiano; Silvia Rossi Paccani; vittorio sambri; Gianfranco Del Prete; Cosima T Baldari; Giuseppe Zanotti; Cesare Montecucco; Mario Milco D'Elios; Marina de Bernard
Borrelia burgdorferi NapA-driven Th17 cell inflammation in lyme arthritis.
Arthritis and rheumatism 2008;58(11):3609-17.
2008: Cristina Ulivieri; Daniela Fanigliulo; Daniela Benati; franco laghi pasini; Cosima T Baldari
Simvastatin impairs humoral and cell-mediated immunity in mice by inhibiting lymphocyte homing, T-cell activation and antigen cross-presentation.
European journal of immunology 2008;38(10):2832-44.
2008: Cristina Ulivieri; Alessandra Citro; Federico Ivaldi; Dina Mascolo; Raffaella Ghittoni; Daniela Fanigliulo; Fabrizio Manca; Cosima T Baldari; Giuseppina Li Pira; Giovanna Del Pozzo
Antigenic properties of HCMV peptides displayed by filamentous bacteriophages vs. synthetic peptides.
Immunology letters 2008;119(1-2):62-70.
2008: Luca Cantarini; Cosima T Baldari; S Rossi Paccani; O M Lucherini; Franco Laghi Pasini; Mauro Galeazzi
Saturday night fever: bizarre recurrence of fever attacks in a patient carrying a mutation in both the MEFV and TNFRSF1A genes.
Clinical and experimental rheumatology 2008;26(4 Suppl 50):S128-9; author reply S129.
2008: Silvia Rossi Paccani; Federica Dal Molin; Marisa Benagiano; Daniel Ladant; Mario Milco D'Elios; Cesare Montecucco; Cosima T Baldari
Suppression of T-lymphocyte activation and chemotaxis by the adenylate cyclase toxin of Bordetella pertussis.
Infection and immunity 2008;76(7):2822-32.
2008: Francesca Finetti; Michela Pellegrini; Cristina Ulivieri; Maria Teresa Savino; Eugenio Paccagnini; Chiara Ginanneschi; Luisa Lanfrancone; Pier Giuseppe Pelicci; Cosima T Baldari
The proapoptotic and antimitogenic protein p66SHC acts as a negative regulator of lymphocyte activation and autoimmunity.
Blood 2008;111(10):5017-27.
2008: Diletta Arcidiacono; Sandra Odom; Barbara Frossi; Juan Rivera; Silvia R Paccani; Cosima T Baldari; Carlo Pucillo; Cesare Montecucco; Marina de Bernard
The Vibrio cholerae cytolysin promotes activation of mast cell (T helper 2) cytokine production.
Cellular microbiology 2008;10(4):899-907.
2008: Laura Patrussi; Cosima T Baldari
Intracellular mediators of CXCR4-dependent signaling in T cells.
Immunology letters 2008;115(2):75-82.
2008: Daniela Benati; Cosima T Baldari
SRC family kinases as potential therapeutic targets for malignancies and immunological disorders.
Current medicinal chemistry 2008;15(12):1154-65.
2007: Laura Patrussi; Stefania Mariggio'; Silvia Rossi Paccani; Nagaja Capitani; Pasquale Zizza; Daniela Corda; Cosima T Baldari
Glycerophosphoinositol-4-phosphate enhances SDF-1alpha-stimulated T-cell chemotaxis through PTK-dependent activation of Vav.
Cellular signalling 2007;19(11):2351-60.
2007: Barbara Orsini; JOSE RAMOS VIVAS; Barbara Ottanelli; Amedeo Amedei; Elisabetta Surrenti; Andrea Galli; Stefano Milani; Pamela Pinzani; Gianfranco Del Prete; Calogero Surrenti; Cosima T Baldari; E Touati; M M D' Elios
Human gastric epithelium produces IL-4 and IL-4delta2 isoform only upon Helicobacter pylori infection.
International journal of immunopathology and pharmacology 2007;20(4):809-18.
2007: Laura Patrussi; Cristina Ulivieri; Orso Maria Lucherini; Silvia Rossi Paccani; Alessandra Gamberucci; Luisa Lanfrancone; Pier Giuseppe Pelicci; Cosima T Baldari
p52Shc is required for CXCR4-dependent signaling and chemotaxis in T cells.
Blood 2007;110(6):1730-8.
2007: Cristina Ulivieri; Cosima T Baldari
The potential of peroxisome proliferator-activated receptor gamma (PPARgamma) ligands in the treatment of hematological malignancies.
Mini reviews in medicinal chemistry 2007;7(9):877-87.
2007: Cosima T Baldari; Gary A Koretzky
Antigen receptor signaling: the Tuscan connection.
Nature immunology 2007;8(8):787-90.
2007: Fabio Carraro; Annalisa Pucci; Michela Pellegrini; Pier Giuseppe Pelicci; Cosima T Baldari; Antonella Naldini
p66Shc is involved in promoting HIF-1alpha accumulation and cell death in hypoxic T cells.
Journal of cellular physiology 2007;211(2):439-47.
2007: Silvia Rossi Paccani; Fiorella Tonello; Laura Patrussi; Nagaja Capitani; Morena Simonato; Cesare Montecucco; Cosima T Baldari
Anthrax toxins inhibit immune cell chemotaxis by perturbing chemokine receptor signalling.
Cellular microbiology 2007;9(4):924-9.
2007: Raffaella Ghittoni; Pietro Enea Lazzerini; Franco Laghi Pasini; Cosima T Baldari
T lymphocytes as targets of statins: molecular mechanisms and therapeutic perspectives.
Inflammation & allergy drug targets 2007;6(1):3-16.
2007: M Pellegrini; F Finetti; Valeria Petronilli; Cristina Ulivieri; Fabiola Giusti; Pietro Lupetti; Marco Giorgio; Pier Giuseppe Pelicci; Paolo Bernardi; Cosima T Baldari
p66SHC promotes T cell apoptosis by inducing mitochondrial dysfunction and impaired Ca2+ homeostasis.
Cell death and differentiation 2007;14(2):338-47.
2006: Raffaella Ghittoni; Giorgio Napolitani; Daniela Benati; Cristina Ulivieri; Cristina Uliveri; Laura Patrussi; Franco Laghi Pasini; Antonio Lanzavecchia; Cosima T Baldari
Simvastatin inhibits the MHC class II pathway of antigen presentation by impairing Ras superfamily GTPases.
European journal of immunology 2006;36(11):2885-93.
2006: Alfredo Pezzicoli; Cristina Ulivieri; Nagaja Capitani; Andrea Ventura; Pier Giuseppe Pelicci; Cosima T Baldari
Expression in T-cells of the proapoptotic protein p66SHC is controlled by promoter demethylation.
Biochemical and biophysical research communications 2006;349(1):322-8.
2006: Cosima T Baldari; Fiorella Tonello; Silvia Rossi Paccani; Cesare Montecucco
Anthrax toxins: A paradigm of bacterial immune suppression.
Trends in immunology 2006;27(9):434-40.
2006: Olga Kogkopoulou; Evaggelos Tzakos; George Mavrothalassitis; Cosima T Baldari; Fotini Paliogianni; Howard A Young; George Thyphronitis
Conditional up-regulation of IL-2 production by p38 MAPK inactivation is mediated by increased Erk1/2 activity.
Journal of leukocyte biology 2006;79(5):1052-60.
2006: Stefania Crotta; Vanessa Ronconi; Cristina Ulivieri; Cosima T Baldari; Nicholas M Valiante; Nicholas M Valiente; Sergio Abrignani; Andreas Wack
Cytoskeleton rearrangement induced by tetraspanin engagement modulates the activation of T and NK cells.
European journal of immunology 2006;36(4):919-29.
2005: Zamal Ahmed; Carolyn A Beeton; Mark A Williams; Darran Clements; Cosima T Baldari; John E Ladbury
Distinct spatial and temporal distribution of ZAP70 and Lck following stimulation of interferon and T-cell receptors.
Journal of molecular biology 2005;353(5):1001-10.
2005: Silvia Rossi Paccani; Marianna Boncristiano; Laura Patrussi; Cristina Ulivieri; Andreas Wack; silvia valensin; Tim Hirst; Amedeo Amedei; Gianfranco Del Prete; John L Telford; Mario Milco D'Elios; Cosima T Baldari
Defective Vav expression and impaired F-actin reorganization in a subset of patients with common variable immunodeficiency characterized by T-cell defects.
Blood 2005;106(2):626-34.
2005: Cosima T Baldari; Antonio Lanzavecchia; John L Telford
Immune subversion by Helicobacter pylori.
Trends in immunology 2005;26(4):199-207.
2005: Raffaella Ghittoni; Laura Patrussi; Katja Pirozzi; Michela Pellegrini; Pietro Enea Lazzerini; Pier Leopoldo Capecchi; Franco Laghi Pasini; Cosima T Baldari
Simvastatin inhibits T-cell activation by selectively impairing the function of Ras superfamily GTPases.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2005;19(6):605-7.
2005: Laura Patrussi; Maria Teresa Savino; Michela Pellegrini; Silvia Rossi Paccani; Enrica Migliaccio; Simon Plyte; Luisa Lanfrancone; Pier Giuseppe Pelicci; Cosima T Baldari
Cooperation and selectivity of the two Grb2 binding sites of p52Shc in T-cell antigen receptor signaling to Ras family GTPases and Myc-dependent survival.
Oncogene 2005;24(13):2218-28.
2005: Silvia Rossi Paccani; Laura Patrussi; Cristina Ulivieri; Jaime L Masferrer; Mario Milco D'Elios; Cosima T Baldari
Nonsteroidal anti-inflammatory drugs inhibit a Fyn-dependent pathway coupled to Rac and stress kinase activation in TCR signaling.
Blood 2005;105(5):2042-8.
2005: Silvia Rossi Paccani; Fiorella Tonello; Raffaella Ghittoni; Mariarita Natale; Lucia Muraro; Mario Milco D'Elios; Wei-Jen Tang; Cesare Montecucco; Cosima T Baldari
Anthrax toxins suppress T lymphocyte activation by disrupting antigen receptor signaling.
The Journal of experimental medicine 2005;201(3):325-31.
2005: Cristina Ulivieri; Cosima T Baldari
The BCR signalosome: where cell fate is decided.
Journal of biological regulators and homeostatic agents 2005;19(1-2):1-16.
2005: Cosima T Baldari; Gary A Koretzky; John L Telford; Oreste Acuto
Antigen receptor signaling: the Tuscan chronicles.
Nature immunology 2005;6(1):3-5.
2004: Antonella Naldini; Fabio Carraro; Cosima T Baldari; Silvia Rossi Paccani; Claudia Bernini; Michael J Keherly; Darrell H Carney
The thrombin peptide, TP508, enhances cytokine release and activates signaling events.
Peptides 2004;25(11):1917-26.
2004: Luca Benetti; Arianna Calistri; Cristina Ulivieri; Anna Cabrelle; Cosima T Baldari; Giorgio Palù; Cristina Parolin
Inhibition of ShcA isoforms p46/p52Shc enhances HIV-1 replication in CD4+ T-lymphocytes.
Journal of cellular physiology 2004;199(1):40-6.
2004: Sonia Pacini; Michela Pellegrini; Enrica Migliaccio; Laura Patrussi; Cristina Ulivieri; Andrea Ventura; Fabio Carraro; Antonella Naldini; Luisa Lanfrancone; Pier Giuseppe Pelicci; Cosima T Baldari
p66SHC promotes apoptosis and antagonizes mitogenic signaling in T cells.
Molecular and cellular biology 2004;24(4):1747-57.
2003: Marianna Boncristiano; Silvia Rossi Paccani; Silvia Barone; Cristina Ulivieri; Laura Patrussi; Dag Ilver; Amedeo Amedei; Mario Milco D'Elios; John L Telford; Cosima T Baldari
The Helicobacter pylori vacuolating toxin inhibits T cell activation by two independent mechanisms.
The Journal of experimental medicine 2003;198(12):1887-97.
2003: S Rossi Paccani; Marianna Boncristiano; Cosima T Baldari
Molecular mechanisms underlying suppression of lymphocyte responses by nonsteroidal antiinflammatory drugs.
Cellular and molecular life sciences : CMLS 2003;60(6):1071-83.
2003: Marisa Benagiano; Annalisa Azzurri; Alessandra Ciervo; Amedeo Amedei; Carlo Tamburini; Mauro Ferrari; John L Telford; Cosima T Baldari; Sergio Romagnani; Antonio Cassone; Mario Milco D'Elios; Gianfranco Del Prete
T helper type 1 lymphocytes drive inflammation in human atherosclerotic lesions.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(11):6658-63.
2003: Elisabetta Soldaini; Andreas Wack; Ugo D'Oro; Sandra Nuti; Cristina Ulivieri; Cosima T Baldari; Sergio Abrignani
T cell costimulation by the hepatitis C virus envelope protein E2 binding to CD81 is mediated by Lck.
European journal of immunology 2003;33(2):455-64.
2003: Cristina Ulivieri; silvia valensin; M Bernardetta Majolini; R James Matthews; Cosima T Baldari
Normal B-1 cell development but defective BCR signaling in Lck-/- mice.
European journal of immunology 2003;33(2):441-5.
2003: Luca Bini; Sonia Pacini; Sabrina Liberatori; silvia valensin; Michela Pellegrini; Roberto Raggiaschi; Vitaliano Pallini; Cosima T Baldari
Extensive temporally regulated reorganization of the lipid raft proteome following T-cell antigen receptor triggering.
The Biochemical journal 2003;369(Pt 2):301-9.
2002: Cosima T Baldari
Antigen receptor signaling under the Tuscan sun.
Nature immunology 2002;3(11):1053-5.
2002: Andrea Ventura; Lucilla Luzi; Sonia Pacini; Cosima T Baldari; Pier Giuseppe Pelicci
The p66Shc longevity gene is silenced through epigenetic modifications of an alternative promoter.
The Journal of biological chemistry 2002;277(25):22370-6.
2002: silvia valensin; Silvia Rossi Paccani; Cristina Ulivieri; David Mercati; Sonia Pacini; Laura Patrussi; Tim Hirst; Pietro Lupetti; Cosima T Baldari
F-actin dynamics control segregation of the TCR signaling cascade to clustered lipid rafts.
European journal of immunology 2002;32(2):435-46.
2002: Silvia Rossi Paccani; Marianna Boncristiano; Cristina Ulivieri; Mario Milco D'Elios; Gianfranco Del Prete; Cosima T Baldari
Nonsteroidal anti-inflammatory drugs suppress T-cell activation by inhibiting p38 MAPK induction.
The Journal of biological chemistry 2002;277(2):1509-13.
2001: Simon Plyte; Marianna Boncristiano; Elena Fattori; Federico Galvagni; Silvia Rossi Paccani; M Bernardetta Majolini; Salvatore Oliviero; G Ciliberto; John L Telford; Cosima T Baldari
Identification and characterization of a novel nuclear factor of activated T-cells-1 isoform expressed in mouse brain.
The Journal of biological chemistry 2001;276(17):14350-8.
2001: Cristina Ulivieri; A Peter; E Orsini; E Palmer; Cosima T Baldari
Defective signaling to Fyn by a T cell antigen receptor lacking the alpha -chain connecting peptide motif.
The Journal of biological chemistry 2001;276(5):3574-80.
2000: Cosima T Baldari; John L Telford; Oreste Acuto
EMBO WORKSHOP REPORT: lymphocyte antigen receptor and coreceptor signaling Siena, Italy, November 6-10, 1999.
The EMBO journal 2000;19(18):4857-65.
2000: Marianna Boncristiano; M Bernardetta Majolini; Mario Milco D'Elios; Sonia Pacini; silvia valensin; Cristina Ulivieri; Amedeo Amedei; B Falini; Gianfranco Del Prete; John L Telford; Cosima T Baldari
Defective recruitment and activation of ZAP-70 in common variable immunodeficiency patients with T cell defects.
European journal of immunology 2000;30(9):2632-8.
2000: Sonia Pacini; silvia valensin; John L Telford; J Ladbury; Cosima T Baldari
Temporally regulated assembly of a dynamic signaling complex associated with the activated TCR.
European journal of immunology 2000;30(9):2620-31.
2000: Simon Plyte; M Bernardetta Majolini; Sonia Pacini; F Scarpini; C Bianchini; Luisa Lanfrancone; Pier Giuseppe Pelicci; Cosima T Baldari
Constitutive activation of the Ras/MAP kinase pathway and enhanced TCR signaling by targeting the Shc adaptor to membrane rafts.
Oncogene 2000;19(12):1529-37.
2000: Cristina Ulivieri; M Bernardetta Majolini; Cosima T Baldari
Restoration of thymic development in an Lck(-/-) thymoma overexpressing ZAP-70.
Molecular immunology 2000;37(1-2):85-90.
1999: Mario Milco D'Elios; Amedeo Amedei; M Manghetti; Francesco Costa; Cosima T Baldari; A S Quazi; John L Telford; Sergio Romagnani; Gianfranco Del Prete
Impaired T-cell regulation of B-cell growth in Helicobacter pylori--related gastric low-grade MALT lymphoma.
Gastroenterology 1999;117(5):1105-12.
1999: M Bernardetta Majolini; Marianna Boncristiano; Cosima T Baldari
Dysregulation of the protein tyrosine kinase LCK in lymphoproliferative disorders and in other neoplasias.
Leukemia & lymphoma 1999;35(3-4):245-54.
1999: Cristina Ulivieri; Sonia Pacini; Sabina Bartalini; silvia valensin; John L Telford; Cosima T Baldari
Obligatory cross-talk with the tyrosine kinases assembled with the TCR/CD3 complex in CD4 signal transduction.
European journal of immunology 1999;29(8):2625-35.
1999: Giovanna Cutrona; N Leanza; Massimo Ulivi; M Bernardetta Majolini; G Taborelli; Simona Zupo; Cosima T Baldari; silvio Roncella; Manlio Ferrarini
Apoptosis induced by crosslinking of CD4 on activated human B cells.
Cellular immunology 1999;193(1):80-9.
1999: Cosima T Baldari; John L Telford
Lymphocyte antigen receptor signal integration and regulation by the SHC adaptor.
Biological chemistry 1999;380(2):129-34.
1998: Sonia Pacini; Cristina Ulivieri; MM Di Somma; A Isacchi; Luisa Lanfrancone; Pier Giuseppe Pelicci; John L Telford; Cosima T Baldari
Tyrosine 474 of ZAP-70 is required for association with the Shc adaptor and for T-cell antigen receptor-dependent gene activation.
The Journal of biological chemistry 1998;273(32):20487-93.
1998: M Bernardetta Majolini; Mario Milco D'Elios; Piero Galieni; Marianna Boncristiano; Francesco Lauria; Gianfranco Del Prete; John L Telford; Cosima T Baldari
Expression of the T-cell-specific tyrosine kinase Lck in normal B-1 cells and in chronic lymphocytic leukemia B cells.
Blood 1998;91(9):3390-6.
1998: Cosima T Baldari; MM Di Somma; M Bernardetta Majolini; Cristina Ulivieri; E Milia; John L Telford
NF-AT-luciferase reporter T cell lines as tools to screen immunosuppressive drugs.
Biologicals : journal of the International Association of Biological Standardization 1998;26(1):1-5.
1997: Mario Milco D'Elios; M Manghetti; Fabio Almerigogna; Amedeo Amedei; Francesco Costa; Daniela Burroni; Cosima T Baldari; Sergio Romagnani; John L Telford; Gianfranco Del Prete
Different cytokine profile and antigen-specificity repertoire in Helicobacter pylori-specific T cell clones from the antrum of chronic gastritis patients with or without peptic ulcer.
European journal of immunology 1997;27(7):1751-5.
1997: M Bernardetta Majolini; Mario Milco D'Elios; Marianna Boncristiano; Piero Galieni; Gianfranco Del Prete; John L Telford; Cosima T Baldari
Uncoupling of T-cell antigen receptor and downstream protein tyrosine kinases in common variable immunodeficiency.
Clinical immunology and immunopathology 1997;84(1):98-102.
1997: E Milia; MM Di Somma; M Bernardetta Majolini; Cristina Ulivieri; F Somma; Enza Piccolella; John L Telford; Cosima T Baldari
Gene activating and proapoptotic potential are independent properties of different CD4 epitopes.
Molecular immunology 1997;34(4):287-96.
1997: Mario Milco D'Elios; M Manghetti; M De Carli; Francesco Costa; Cosima T Baldari; Daniela Burroni; John L Telford; Sergio Romagnani; Gianfranco Del Prete
T helper 1 effector cells specific for Helicobacter pylori in the gastric antrum of patients with peptic ulcer disease.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(2):962-7.
1996: Cristina Ulivieri; Daniela Burroni; John L Telford; Cosima T Baldari
Generation of a monoclonal antibody to a defined portion of the Helicobacter pylori vacuolating cytotoxin by DNA immunization.
Journal of biotechnology 1996;51(2):191-4.
1996: Marco Rosetto; AG Manetti; Piero C Giordano; Laura Marri; R Amons; Cosima T Baldari; Daniela Marchini; Romano Dallai
Molecular characterization of ceratotoxin C, a novel antibacterial female-specific peptide of the ceratotoxin family from the medfly Ceratitis capitata.
European journal of biochemistry / FEBS 1996;241(2):330-7.
1996: MM Di Somma; M Bernardetta Majolini; S E Burastero; John L Telford; Cosima T Baldari
Cyclosporin A sensitivity of the HIV-1 long terminal repeat identifies distinct p56lck-dependent pathways activated by CD4 triggering.
European journal of immunology 1996;26(9):2181-8.
1996: E Milia; MM Di Somma; F Baldoni; R Chiari; Luisa Lanfrancone; Pier Giuseppe Pelicci; John L Telford; Cosima T Baldari
The aminoterminal phosphotyrosine binding domain of Shc associates with ZAP-70 and mediates TCR dependent gene activation.
Oncogene 1996;13(4):767-75.
1995: Cosima T Baldari; E Milia; MM Di Somma; F Baldoni; S Valitutti; John L Telford
Distinct signaling properties identify functionally different CD4 epitopes.
European journal of immunology 1995;25(7):1843-50.
1995: MM Di Somma; Sandra Nuti; John L Telford; Cosima T Baldari
p56lck plays a key role in transducing apoptotic signals in T cells.
FEBS letters 1995;363(1-2):101-4.
1995: Marco Rosetto; Ylva Engström; Cosima T Baldari; John L Telford; Dan Hultmark
Signals from the IL-1 receptor homolog, Toll, can activate an immune response in a Drosophila hemocyte cell line.
Biochemical and biophysical research communications 1995;209(1):111-6.
1995: Cosima T Baldari; MM Di Somma; E Milia; M Bergman; John L Telford
Interactions between the tyrosine kinases p56lck, p59fyn and p50csk in CD4 signaling in T cells.
European journal of immunology 1995;25(4):919-25.
1995: Daniela Marchini; AG Manetti; Marco Rosetto; L F Bernini; John L Telford; Cosima T Baldari; Romano Dallai
cDNA sequence and expression of the ceratotoxin gene encoding an antibacterial sex-specific peptide from the medfly Ceratitis capitata (diptera).
The Journal of biological chemistry 1995;270(11):6199-204.
1995: Cosima T Baldari; Giuliana Pelicci; MM Di Somma; E Milia; S Giuli; Pier Giuseppe Pelicci; John L Telford
Inhibition of CD4/p56lck signaling by a dominant negative mutant of the Shc adaptor protein.
Oncogene 1995;10(6):1141-7.
1994: T M Werge; Cosima T Baldari; John L Telford
Intracellular single chain Fv antibody inhibits Ras activity in T-cell antigen receptor stimulated Jurkat cells.
FEBS letters 1994;351(3):393-6.
1994: Cosima T Baldari; John L Telford
Dissection of T cell antigen receptor signaling using protein tyrosine kinase inhibitors.
European journal of immunology 1994;24(5):1046-52.
1994: Cosima T Baldari; A Heguy; MM Di Somma; John L Telford
Inhibition of T-cell antigen receptor signaling by overexpression of p120GAP.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1994;5(1):95-8.
1993: Marco Rosetto; AG Manetti; Daniela Marchini; Romano Dallai; John L Telford; Cosima T Baldari
Sequences of two cDNA clones from the medfly Ceratitis capitata encoding antibacterial peptides of the cecropin family.
Gene 1993;134(2):241-3.
1993: Cosima T Baldari; A Heguy; John L Telford
Calcium dependent activation of the NF-AT transcription factor by p59fyn.
FEBS letters 1993;323(3):233-5.
1993: A Heguy; Cosima T Baldari; Stefano Censini; P Ghiara; John L Telford
A chimeric type II/type I interleukin-1 receptor can mediate interleukin-1 induction of gene expression in T cells.
The Journal of biological chemistry 1993;268(14):10490-4.
1993: Cosima T Baldari; A Heguy; John L Telford
Calcium-dependent cyclosporin A-sensitive activation of the interleukin-2 promoter by p56lck.
The Journal of biological chemistry 1993;268(12):8406-9.
1993: Cosima T Baldari; A Heguy; John L Telford
ras protein activity is essential for T-cell antigen receptor signal transduction.
The Journal of biological chemistry 1993;268(4):2693-8.
1992: Cosima T Baldari; G Macchia; A Massone; John L Telford
p21ras contributes to HIV-1 activation in T-cells.
FEBS letters 1992;304(2-3):261-4.
1992: Cosima T Baldari; G Macchia; John L Telford
Interleukin-2 promoter activation in T-cells expressing activated Ha-ras.
The Journal of biological chemistry 1992;267(7):4289-91.
1992: A Heguy; Cosima T Baldari; G Macchia; John L Telford; M Melli
Amino acids conserved in interleukin-1 receptors (IL-1Rs) and the Drosophila toll protein are essential for IL-1R signal transduction.
The Journal of biological chemistry 1992;267(4):2605-9.
1991: Cosima T Baldari; G Macchia; A Heguy; M Melli; John L Telford
Cyclosporin A blocks calcium-dependent pathways of gene activation.
The Journal of biological chemistry 1991;266(28):19103-8.
1991: A Heguy; Cosima T Baldari; K Bush; Robert G Nagele; R C Newton; R J Robb; richard horuk; John L Telford; M Melli
Internalization and nuclear localization of interleukin 1 are not sufficient for function.
Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research 1991;2(7):311-5.
1990: D Donati; Cosima T Baldari; G Macchia; A Massone; John L Telford; Luca Parente
Induction of gene expression by IL-1 in NIH 3T3 cells. Possible requirement of protein kinase C activity and independence from arachidonic acid metabolism.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4115-20.
1990: G Macchia; Cosima T Baldari; A Massone; John L Telford
A role for protein kinase C activity in interleukin-1 (IL-1) induction of IL-2 gene expression but not in IL-1 signal transduction.
Molecular and cellular biology 1990;10(6):2731-7.
1990: G Macchia; Cosima T Baldari; A Massone; D Donati; Luca Parente; John L Telford
Activation of gene expression by interleukin 1.
Progress in clinical and biological research 1990;349():329-41.
1989: M Bigio; R Rossi; M G Borri; M C Casagli; D Nucci; Cosima T Baldari; G Volpini; Diana Boraschi
One-step immunoaffinity purification of bioactive human recombinant IL-1 beta with a monoclonal antibody directed to a well-exposed domain of the protein.
Journal of immunological methods 1989;123(1):1-8.
1989: Cosima T Baldari; John L Telford
The intracellular precursor of IL-1 beta is associated with microtubules in activated U937 cells.
Journal of immunology (Baltimore, Md. : 1950) 1989;142(3):785-91.
1988: A Massone; Cosima T Baldari; Stefano Censini; M Bartalini; D Nucci; Diana Boraschi; John L Telford
Mapping of biologically relevant sites on human IL-1 beta using monoclonal antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(11):3812-6.
1987: Cosima T Baldari; A Massone; G Macchia; John L Telford
Differential stability of human interleukin 1 beta fragments expressed in yeast.
Protein engineering 1987;1(5):433-7.