Kenneth Korach

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Liu Suhuan; Le May Cedric; Wong Winifred P S; Ward Robert D; Clegg Deborah J; Marcelli Marco; Korach Kenneth S; Mauvais-Jarvis Franck
Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival.
Cleveland Alicia G; Oikarinen Seija I; Bynoté Kimberly K; Marttinen Maija; Rafter Joseph J; Gustafsson Jan-Ake; Roy Shyamal K; Pitot Henry C; Korach Kenneth S; Lubahn Dennis B; Mutanen Marja; Gould Karen A
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice.
Deroo Bonnie J; Hewitt Sylvia C; Collins Jennifer B; Grissom Sherry F; Hamilton Katherine J; Korach Kenneth S
Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model.

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All Publications

2009: Liu Suhuan; Le May Cedric; Wong Winifred P S; Ward Robert D; Clegg Deborah J; Marcelli Marco; Korach Kenneth S; Mauvais-Jarvis Franck
Importance of extranuclear estrogen receptor-alpha and membrane G protein-coupled estrogen receptor in pancreatic islet survival.
Diabetes 2009;58(10):2292-302.
2009: Cleveland Alicia G; Oikarinen Seija I; Bynoté Kimberly K; Marttinen Maija; Rafter Joseph J; Gustafsson Jan-Ake; Roy Shyamal K; Pitot Henry C; Korach Kenneth S; Lubahn Dennis B; Mutanen Marja; Gould Karen A
Disruption of estrogen receptor signaling enhances intestinal neoplasia in Apc(Min/+) mice.
Carcinogenesis 2009;30(9):1581-90.
2009: Deroo Bonnie J; Hewitt Sylvia C; Collins Jennifer B; Grissom Sherry F; Hamilton Katherine J; Korach Kenneth S
Profile of estrogen-responsive genes in an estrogen-specific mammary gland outgrowth model.
Molecular reproduction and development 2009;76(8):733-50.
2009: Deroo Bonnie J; Rodriguez Karina F; Couse John F; Hamilton Katherine J; Collins Jennifer B; Grissom Sherry F; Korach Kenneth S
Estrogen receptor beta is required for optimal cAMP production in mouse granulosa cells.
Molecular endocrinology (Baltimore, Md.) 2009;23(7):955-65.
2009: Tomihara Kazuya; Soga Tomoko; Nomura Masayoshi; Korach Kenneth S; Gustafsson Jan-Ake; Pfaff Donald W; Ogawa Sonoko
Effect of ER-beta gene disruption on estrogenic regulation of anxiety in female mice.
Physiology & behavior 2009;96(2):300-6.
2008: Chung Sang-Hyuk; Wiedmeyer Kerri; Shai Anny; Korach Kenneth S; Lambert Paul F
Requirement for estrogen receptor alpha in a mouse model for human papillomavirus-associated cervical cancer.
Cancer research 2008;68(23):9928-34.
2008: Weiss Jeffrey; Bernhardt Miranda L; Laronda Monica M; Hurley Lisa A; Glidewell-Kenney Christine; Pillai Suresh; Tong Minghan; Korach Kenneth S; Jameson J Larry
Estrogen actions in the male reproductive system involve estrogen response element-independent pathways.
Endocrinology 2008;149(12):6198-206.
2008: Athirakul Krairerk; Bradbury J Alyce; Graves Joan P; DeGraff Laura M; Ma Jixiang; Zhao Yun; Couse John F; Quigley Raymond; Harder David R; Zhao Xueying; Imig John D; Pedersen Theresa L; Newman John W; Hammock Bruce D; Conley Alan J; Korach Kenneth S; Coffman Thomas M; Zeldin Darryl C
Increased blood pressure in mice lacking cytochrome P450 2J5.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(12):4096-108.
2008: Svenson John L; EuDaly Jackie; Ruiz Phil; Korach Kenneth S; Gilkeson Gary S
Impact of estrogen receptor deficiency on disease expression in the NZM2410 lupus prone mouse.
Clinical immunology (Orlando, Fla.) 2008;128(2):259-68.
2008: Smith Eric P; Specker Bonny; Bachrach Bert E; Kimbro K S; Li X J; Young Marian F; Fedarko Neal S; Abuzzahab M J; Frank Graeme R; Cohen Robert M; Lubahn Dennis B; Korach Kenneth S
Impact on bone of an estrogen receptor-alpha gene loss of function mutation.
The Journal of clinical endocrinology and metabolism 2008;93(8):3088-96.
2008: Voltz James W; Card Jeffrey W; Carey Michelle A; Degraff Laura M; Ferguson Catherine D; Flake Gordon P; Bonner James C; Korach Kenneth S; Zeldin Darryl C
Male sex hormones exacerbate lung function impairment after bleomycin-induced pulmonary fibrosis.
American journal of respiratory cell and molecular biology 2008;39(1):45-52.
2008: Kavaliers Martin; Devidze Nino; Choleris Elena; Fudge Melissa; Gustafsson Jan-Ake; Korach Kenneth S; Pfaff Donald W; Ogawa Sonoko
Estrogen receptors alpha and beta mediate different aspects of the facilitatory effects of female cues on male risk taking.
Psychoneuroendocrinology 2008;33(5):634-42.
2008: Sinkevicius Kerstin W; Burdette Joanna E; Woloszyn Karolina; Hewitt Sylvia C; Hamilton Katherine; Sugg Sonia L; Temple Karla A; Wondisford Fredric E; Korach Kenneth S; Woodruff Teresa K; Greene Geoffrey L
An estrogen receptor-alpha knock-in mutation provides evidence of ligand-independent signaling and allows modulation of ligand-induced pathways in vivo.
Endocrinology 2008;149(6):2970-9.
2008: Prins Gail S; Korach Kenneth S
The role of estrogens and estrogen receptors in normal prostate growth and disease.
Steroids 2008;73(3):233-44.
2008: Liu Dianxin; Deschamps Anne; Korach Kenneth S; Murphy Elizabeth
Estrogen-enhanced gene expression of lipoprotein lipase in heart is antagonized by progesterone.
Endocrinology 2008;149(2):711-6.
2007: Umetani Michihisa; Domoto Hideharu; Gormley Andrew K; Yuhanna Ivan S; Cummins Carolyn L; Javitt Norman B; Korach Kenneth S; Shaul Philip W; Mangelsdorf David J
27-Hydroxycholesterol is an endogenous SERM that inhibits the cardiovascular effects of estrogen.
Nature medicine 2007;13(10):1185-92.
2007: Carey Michelle A; Card Jeffrey W; Voltz James W; Arbes Samuel J; Germolec Dori R; Korach Kenneth S; Zeldin Darryl C
It's all about sex: gender, lung development and lung disease.
Trends in endocrinology and metabolism: TEM 2007;18(8):308-13.
2007: Carey Michelle A; Card Jeffrey W; Voltz James W; Germolec Dori R; Korach Kenneth S; Zeldin Darryl C
The impact of sex and sex hormones on lung physiology and disease: lessons from animal studies.
American journal of physiology. Lung cellular and molecular physiology 2007;293(2):L272-8.
2007: Gougelet Angélique; Mueller Stefan O; Korach Ken S; Renoir Jack-Michel
Oestrogen receptors pathways to oestrogen responsive elements: the transactivation function-1 acts as the keystone of oestrogen receptor (ER)beta-mediated transcriptional repression of ERalpha.
The Journal of steroid biochemistry and molecular biology 2007;104(3-5):110-22.
2007: Wang Jianxun; Scully Kathleen; Zhu Xiaoyan; Cai Ling; Zhang Jie; Prefontaine Gratien G; Krones Anna; Ohgi Kenneth A; Zhu Ping; Garcia-Bassets Ivan; Liu Forrest; Taylor Havilah; Lozach Jean; Jayes Friederike L; Korach Kenneth S; Glass Christopher K; Fu Xiang-Dong; Rosenfeld Michael G
Opposing LSD1 complexes function in developmental gene activation and repression programmes.
Nature 2007;446(7138):882-7.
2007: Henley Derek V; Lipson Natasha; Korach Kenneth S; Bloch Clifford A
Prepubertal gynecomastia linked to lavender and tea tree oils.
The New England journal of medicine 2007;356(5):479-85.
2007: Taniguchi Fuminori; Couse John F; Rodriguez Karina F; Emmen Judith M A; Poirier Donald; Korach Kenneth S
Estrogen receptor-alpha mediates an intraovarian negative feedback loop on thecal cell steroidogenesis via modulation of Cyp17a1 (cytochrome P450, steroid 17alpha-hydroxylase/17,20 lyase) expression.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2007;21(2):586-95.
2007: Carey Michelle A; Card Jeffrey W; Bradbury J Alyce; Moorman Michael P; Haykal-Coates Najwa; Gavett Stephen H; Graves Joan P; Walker Vickie R; Flake Gordon P; Voltz James W; Zhu Daling; Jacobs Elizabeth R; Dakhama Azzeddine; Larsen Gary L; Loader Joan E; Gelfand Erwin W; Germolec Dori R; Korach Kenneth S; Zeldin Darryl C
Spontaneous airway hyperresponsiveness in estrogen receptor-alpha-deficient mice.
American journal of respiratory and critical care medicine 2007;175(2):126-35.
2006: Carpenter Karen D; Korach Kenneth S
Potential biological functions emerging from the different estrogen receptors.
Annals of the New York Academy of Sciences 2006;1092():361-73.
2006: Dahlman-Wright Karin; Cavailles Vincent; Fuqua Suzanne A; Jordan V Craig; Katzenellenbogen John A; Korach Kenneth S; Maggi Adriana; Muramatsu Masami; Parker Malcolm G; Gustafsson Jan-Ake
International Union of Pharmacology. LXIV. Estrogen receptors.
Pharmacological reviews 2006;58(4):773-81.
2006: Lindzey Jonathan; Jayes Friederike L; Yates Mariana M; Couse John F; Korach Kenneth S
The bi-modal effects of estradiol on gonadotropin synthesis and secretion in female mice are dependent on estrogen receptor-alpha.
The Journal of endocrinology 2006;191(1):309-17.
2006: Wintermantel Tim M; Campbell Rebecca E; Porteous Robert; Bock Dagmar; Gröne Hermann-Josef; Todman Martin G; Korach Kenneth S; Greiner Erich; Pérez Cristian A; Schütz Günther; Herbison Allan E
Definition of estrogen receptor pathway critical for estrogen positive feedback to gonadotropin-releasing hormone neurons and fertility.
Neuron 2006;52(2):271-80.
2006: O'Brien Jeanne E; Peterson Theresa J; Tong Ming Han; Lee Eun-Jig; Pfaff Liza E; Hewitt Sylvia C; Korach Kenneth S; Weiss Jeffrey; Jameson J Larry
Estrogen-induced proliferation of uterine epithelial cells is independent of estrogen receptor alpha binding to classical estrogen response elements.
The Journal of biological chemistry 2006;281(36):26683-92.
2006: Couse John F; Yates Mariana M; Rodriguez Karina F; Johnson Jo Anne; Poirier Donald; Korach Kenneth S
The intraovarian actions of estrogen receptor-alpha are necessary to repress the formation of morphological and functional Leydig-like cells in the female gonad.
Endocrinology 2006;147(8):3666-78.
2006: Tomihara Kazuya; Kaitsuka Taku; Soga Tomoko; Korach Kenneth S; Pfaff Donald W; Takahama Kazuo; Ogawa Sonoko
Abolition of sex-dependent effects of prenatal exposure to diethylstilbestrol on emotional behavior in estrogen receptor-alpha knockout mice.
Neuroreport 2006;17(11):1169-73.
2006: Schmitt M; Walker M P; Richards R G; Bocchinfuso W P; Fukuda T; Medina D; Kittrell F S; Korach K S; DiAugustine R P
Expression of heregulin by mouse mammary tumor cells: role in activation of ErbB receptors.
Molecular carcinogenesis 2006;45(7):490-505.
2006: Le May Cedric; Chu Khoi; Hu Min; Ortega Christina S; Simpson Evan R; Korach Kenneth S; Tsai Ming-Jer; Mauvais-Jarvis Franck
Estrogens protect pancreatic beta-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(24):9232-7.
2006: Henley Derek V; Korach Kenneth S
Endocrine-disrupting chemicals use distinct mechanisms of action to modulate endocrine system function.
Endocrinology 2006;147(6 Suppl):S25-32.
2006: Yamamoto Yukio; Moore Rick; Hess Holly A; Guo Grace L; Gonzalez Frank J; Korach Kenneth S; Maronpot Robert R; Negishi Masahiko
Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity.
The Journal of biological chemistry 2006;281(24):16625-31.
2006: Qiu Jian; Bosch Martha A; Tobias Sandra C; Krust Andree; Graham Sharon M; Murphy Stephanie J; Korach Kenneth S; Chambon Pierre; Scanlan Thomas S; Rønnekleiv Oline K; Kelly Martin J
A G-protein-coupled estrogen receptor is involved in hypothalamic control of energy homeostasis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(21):5649-55.
2006: Hewitt Sylvia C; Collins Jennifer; Grissom Sherry; Hamilton Katherine; Korach Kenneth S
Estren behaves as a weak estrogen rather than a nongenomic selective activator in the mouse uterus.
Endocrinology 2006;147(5):2203-14.
2006: Nomura Masayoshi; Andersson Sandra; Korach Kenneth S; Gustafsson Jan-Ake; Pfaff Donald W; Ogawa Sonoko
Estrogen receptor-beta gene disruption potentiates estrogen-inducible aggression but not sexual behaviour in male mice.
The European journal of neuroscience 2006;23(7):1860-8.
2006: Szego Eva M; Barabás Klaudia; Balog Júlia; Szilágyi Nóra; Korach Kenneth S; Juhász Gábor; Abrahám István M
Estrogen induces estrogen receptor alpha-dependent cAMP response element-binding protein phosphorylation via mitogen activated protein kinase pathway in basal forebrain cholinergic neurons in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(15):4104-10.
2006: Deroo Bonnie J; Korach Kenneth S
Estrogen receptors and human disease.
The Journal of clinical investigation 2006;116(3):561-70.
2006: Taylor R A; Cowin P; Couse J F; Korach K S; Risbridger G P
17beta-estradiol induces apoptosis in the developing rodent prostate independently of ERalpha or ERbeta.
Endocrinology 2006;147(1):191-200.
2005: Aoyama Hiroaki; Couse John F; Hewitt Sylvia C; Haseman Joseph K; He Hong; Zheng Xiaolin; Majstoravich Sonja; Korach Kenneth S; Dixon D
Upregulation of estrogen receptor expression in the uterus of ovariectomized B6C3F1 mice and Ishikawa cells treated with bromoethane.
Toxicology and applied pharmacology 2005;209(3):226-35.
2005: Couse John F; Yates Mariana M; Deroo Bonnie J; Korach Kenneth S
Estrogen receptor-beta is critical to granulosa cell differentiation and the ovulatory response to gonadotropins.
Endocrinology 2005;146(8):3247-62.
2005: Jayachandran Muthuvel; Karnicki Krzysztof; Miller Randall S; Owen Whyte G; Korach Kenneth S; Miller Virginia M
Platelet characteristics change with aging: role of estrogen receptor beta.
The journals of gerontology. Series A, Biological sciences and medical sciences 2005;60(7):815-9.
2005: Emmen Judith M A; Couse John F; Elmore Susan A; Yates Mariana M; Kissling Grace E; Korach Kenneth S
In vitro growth and ovulation of follicles from ovaries of estrogen receptor (ER){alpha} and ER{beta} null mice indicate a role for ER{beta} in follicular maturation.
Endocrinology 2005;146(6):2817-26.
2005: Tekmal Rajeshwar Rao; Liu Ya-Guang; Nair Hareesh B; Jones Jeremy; Perla Rao P; Lubahn Dennis B; Korach Kenneth S; Kirma Nameer
Estrogen receptor alpha is required for mammary development and the induction of mammary hyperplasia and epigenetic alterations in the aromatase transgenic mice.
The Journal of steroid biochemistry and molecular biology 2005;95(1-5):9-15.
2005: Pelzer Theo; Loza Paula-Anahi Arias; Hu Kai; Bayer Barbara; Dienesch Charlotte; Calvillo Laura; Couse John F; Korach Kenneth S; Neyses Ludwig; Ertl Georg
Increased mortality and aggravation of heart failure in estrogen receptor-beta knockout mice after myocardial infarction.
Circulation 2005;111(12):1492-8.
2005: Hewitt Sylvia Curtis; Deroo Bonnie J; Korach Kenneth S
Signal transduction. A new mediator for an old hormone?
Science (New York, N.Y.) 2005;307(5715):1572-3.
2005: Hewitt Sylvia Curtis; Collins Jennifer; Grissom Sherry; Deroo Bonnie; Korach Kenneth S
Global uterine genomics in vivo: microarray evaluation of the estrogen receptor alpha-growth factor cross-talk mechanism.
Molecular endocrinology (Baltimore, Md.) 2005;19(3):657-68.
2005: Gougelet Angélique; Bouclier Céline; Marsaud Véronique; Maillard Sébastien; Mueller Stefan O; Korach Kenneth S; Renoir Jack-Michel
Estrogen receptor alpha and beta subtype expression and transactivation capacity are differentially affected by receptor-, hsp90- and immunophilin-ligands in human breast cancer cells.
The Journal of steroid biochemistry and molecular biology 2005;94(1-3):71-81.
2005: Gabel Scott A; Walker Vickie R; London Robert E; Steenbergen Charles; Korach Kenneth S; Murphy Elizabeth
Estrogen receptor beta mediates gender differences in ischemia/reperfusion injury.
Journal of molecular and cellular cardiology 2005;38(2):289-97.
2005: Ardelt Agnieszka A; McCullough Louise D; Korach Kenneth S; Wang Michael M; Munzenmaier Diane H; Hurn Patricia D
Estradiol regulates angiopoietin-1 mRNA expression through estrogen receptor-alpha in a rodent experimental stroke model.
Stroke; a journal of cerebral circulation 2005;36(2):337-41.
2005: Skavdahl Maryanne; Steenbergen Charles; Clark James; Myers Page; Demianenko Tracy; Mao Lan; Rockman Howard A; Korach Kenneth S; Murphy Elizabeth
Estrogen receptor-beta mediates male-female differences in the development of pressure overload hypertrophy.
American journal of physiology. Heart and circulatory physiology 2005;288(2):H469-76.
2005: Yue Wei; Wang Ji-Ping; Li Yuebai; Bocchinfuso Wayne P; Korach Kenneth S; Devanesan Prabu D; Rogan Eleanor; Cavalieri Ercole; Santen Richard J
Tamoxifen versus aromatase inhibitors for breast cancer prevention.
Clinical cancer research : an official journal of the American Association for Cancer Research 2005;11(2 Pt 2):925s-30s.
2005: Hewitt Sylvia C; Harrell Joshua C; Korach Kenneth S
Lessons in estrogen biology from knockout and transgenic animals.
Annual review of physiology 2005;67():285-308.
2005: Nomura M; Akama K T; Alves S E; Korach K S; Gustafsson J-A; Pfaff D W; Ogawa S
Differential distribution of estrogen receptor (ER)-alpha and ER-beta in the midbrain raphe nuclei and periaqueductal gray in male mouse: Predominant role of ER-beta in midbrain serotonergic systems.
Neuroscience 2005;130(2):445-56.
2004: Couse John F; Korach Kenneth S
Estrogen receptor-alpha mediates the detrimental effects of neonatal diethylstilbestrol (DES) exposure in the murine reproductive tract.
Toxicology 2004;205(1-2):55-63.
2004: Deroo Bonnie J; Hewitt Sylvia C; Peddada Shyamal D; Korach Kenneth S
Estradiol regulates the thioredoxin antioxidant system in the mouse uterus.
Endocrinology 2004;145(12):5485-92.
2004: Couse John F; Yates Mariana M; Sanford Ryan; Nyska Abraham; Nilson John H; Korach Kenneth S
Formation of cystic ovarian follicles associated with elevated luteinizing hormone requires estrogen receptor-beta.
Endocrinology 2004;145(10):4693-702.
2004: Mueller Stefan O; Katzenellenbogen John A; Korach Kenneth S
Endogenous estrogen receptor beta is transcriptionally active in primary ovarian cells from estrogen receptor knockout mice.
Steroids 2004;69(10):681-6.
2004: Lovegrove Alecia S; Sun Jianhong; Gould Karen A; Lubahn Dennis B; Korach Kenneth S; Lane Pascale H
Estrogen receptor alpha-mediated events promote sex-specific diabetic glomerular hypertrophy.
American journal of physiology. Renal physiology 2004;287(3):F586-91.
2004: Mueller Stefan O; Simon Stephanie; Chae Kun; Metzler Manfred; Korach Kenneth S
Phytoestrogens and their human metabolites show distinct agonistic and antagonistic properties on estrogen receptor alpha (ERalpha) and ERbeta in human cells.
Toxicological sciences : an official journal of the Society of Toxicology 2004;80(1):14-25.
2004: Abrahám István M; Todman Martin G; Korach Kenneth S; Herbison Allan E
Critical in vivo roles for classical estrogen receptors in rapid estrogen actions on intracellular signaling in mouse brain.
Endocrinology 2004;145(7):3055-61.
2004: Ma Jixiang; Graves Joan; Bradbury J Alyce; Zhao Yun; Swope Deborah L; King Lorraine; Qu Wei; Clark James; Myers Page; Walker Vickie; Lindzey Jonathan; Korach Kenneth S; Zeldin Darryl C
Regulation of mouse renal CYP2J5 expression by sex hormones.
Molecular pharmacology 2004;65(3):730-43.
2004: Harada Hirohisa; Bharwani Sulaiman; Pavlick Kevin P; Korach Kenneth S; Grisham Matthew B
Estrogen receptor-alpha, sexual dimorphism and reduced-size liver ischemia and reperfusion injury in mice.
Pediatric research 2004;55(3):450-6.
2004: Longo Maurizio; Brama Marina; Marino Maria; Bernardini Silvia; Korach Kenneth S; Wetsel William C; Scandurra Roberto; Faraggiana Tullio; Spera Giovanni; Baron Roland; Teti Anna; Migliaccio Silvia
Interaction of estrogen receptor alpha with protein kinase C alpha and c-Src in osteoblasts during differentiation.
Bone 2004;34(1):100-11.
2004: Walker Vickie R; Korach Kenneth S
Estrogen receptor knockout mice as a model for endocrine research.
ILAR journal / National Research Council, Institute of Laboratory Animal Resources 2004;45(4):455-61.
2003: He Bin; Rhodes-Brower Stacey; Miller Michael R; Munson Albert E; Germolec Dori R; Walker Vickie R; Korach Kenneth S; Meade B Jean
Octamethylcyclotetrasiloxane exhibits estrogenic activity in mice via ERalpha.
Toxicology and applied pharmacology 2003;192(3):254-61.
2003: Dorling Amber A; Todman Martin G; Korach Kenneth S; Herbison Allan E
Critical role for estrogen receptor alpha in negative feedback regulation of gonadotropin-releasing hormone mRNA expression in the female mouse.
Neuroendocrinology 2003;78(4):204-9.
2003: Hewitt Sylvia Curtis; Deroo Bonnie J; Hansen Katherine; Collins Jennifer; Grissom Sherry; Afshari Cynthia A; Korach Kenneth S
Estrogen receptor-dependent genomic responses in the uterus mirror the biphasic physiological response to estrogen.
Molecular endocrinology (Baltimore, Md.) 2003;17(10):2070-83.
2003: Burns Kathleen H; Agno Julio E; Chen Lei; Haupt Bisong; Ogbonna Samuel C; Korach Kenneth S; Matzuk Martin M
Sexually dimorphic roles of steroid hormone receptor signaling in gonadal tumorigenesis.
Molecular endocrinology (Baltimore, Md.) 2003;17(10):2039-52.
2003: Yue W; Santen R J; Wang J-P; Li Y; Verderame M F; Bocchinfuso W P; Korach K S; Devanesan P; Todorovic R; Rogan E G; Cavalieri E L
Genotoxic metabolites of estradiol in breast: potential mechanism of estradiol induced carcinogenesis.
The Journal of steroid biochemistry and molecular biology 2003;86(3-5):477-86.
2003: Korach Kenneth S; Emmen Judith M A; Walker Vickie R; Hewitt Sylvia C; Yates Mariana; Hall Julie M; Swope Deborah L; Harrell Joshua C; Couse John F
Update on animal models developed for analyses of estrogen receptor biological activity.
The Journal of steroid biochemistry and molecular biology 2003;86(3-5):387-91.
2003: Garey J; Goodwillie A; Frohlich J; Morgan M; Gustafsson J-A; Smithies O; Korach K S; Ogawa S; Pfaff D W
Genetic contributions to generalized arousal of brain and behavior.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(19):11019-22.
2003: Abrahám István M; Han Seong-Kyu; Todman Martin G; Korach Kenneth S; Herbison Allan E
Estrogen receptor beta mediates rapid estrogen actions on gonadotropin-releasing hormone neurons in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(13):5771-7.
2003: Couse John F; Yates Mariana M; Walker Vickie R; Korach Kenneth S
Characterization of the hypothalamic-pituitary-gonadal axis in estrogen receptor (ER) Null mice reveals hypergonadism and endocrine sex reversal in females lacking ERalpha but not ERbeta.
Molecular endocrinology (Baltimore, Md.) 2003;17(6):1039-53.
2003: Kenney Nicholas J; Bowman Arthur; Korach Kenneth S; Barrett J Carl; Salomon David S
Effect of exogenous epidermal-like growth factors on mammary gland development and differentiation in the estrogen receptor-alpha knockout (ERKO) mouse.
Breast cancer research and treatment 2003;79(2):161-73.
2003: Choleris Elena; Gustafsson Jan-Ake; Korach Kenneth S; Muglia Louis J; Pfaff Donald W; Ogawa Sonoko
An estrogen-dependent four-gene micronet regulating social recognition: a study with oxytocin and estrogen receptor-alpha and -beta knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(10):6192-7.
2003: McDougall Kathleen E; Perry Mark J; Gibson Rachel L; Colley Shane M; Korach Kenneth S; Tobias Jonathan H
Estrogen receptor-alpha dependency of estrogen's stimulatory action on cancellous bone formation in male mice.
Endocrinology 2003;144(5):1994-9.
2003: Hall Julie M; Korach Kenneth S
Stromal cell-derived factor 1, a novel target of estrogen receptor action, mediates the mitogenic effects of estradiol in ovarian and breast cancer cells.
Molecular endocrinology (Baltimore, Md.) 2003;17(5):792-803.
2003: Emmen J M A; Korach K S
Estrogen receptor knockout mice: phenotypes in the female reproductive tract.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology 2003;17(2):169-76.
2003: Borzychowski A M; Chantakru S; Minhas K; Paffaro V A; Yamada A T; He H; Korach K S; Croy B A
Functional analysis of murine uterine natural killer cells genetically devoid of oestrogen receptors.
Placenta 2003;24(4):403-11.
2003: Mueller Stefan O; Hall Julie M; Swope Deborah L; Pedersen Lars C; Korach Kenneth S
Molecular determinants of the stereoselectivity of agonist activity of estrogen receptors (ER) alpha and beta.
The Journal of biological chemistry 2003;278(14):12255-62.
2003: Hewitt Sylvia Curtis; Korach Kenneth S
Oestrogen receptor knockout mice: roles for oestrogen receptors alpha and beta in reproductive tissues.
Reproduction (Cambridge, England) 2003;125(2):143-9.
2003: Nomura Masayoshi; Korach Kenneth S; Pfaff Donald W; Ogawa Sonoko
Estrogen receptor beta (ERbeta) protein levels in neurons depend on estrogen receptor alpha (ERalpha) gene expression and on its ligand in a brain region-specific manner.
Brain research. Molecular brain research 2003;110(1):7-14.
2003: Ogawa Sonoko; Chan Johnny; Gustafsson Jan-Ake; Korach Kenneth S; Pfaff Donald W
Estrogen increases locomotor activity in mice through estrogen receptor alpha: specificity for the type of activity.
Endocrinology 2003;144(1):230-9.
2003: Akingbemi Benson T; Ge Renshan; Rosenfeld Cheryl S; Newton Leslie G; Hardy Dianne O; Catterall James F; Lubahn Dennis B; Korach Kenneth S; Hardy Matthew P
Estrogen receptor-alpha gene deficiency enhances androgen biosynthesis in the mouse Leydig cell.
Endocrinology 2003;144(1):84-93.
2002: Nomura Masayoshi; McKenna Elizabeth; Korach Kenneth S; Pfaff Donald W; Ogawa Sonoko
Estrogen receptor-beta regulates transcript levels for oxytocin and arginine vasopressin in the hypothalamic paraventricular nucleus of male mice.
Brain research. Molecular brain research 2002;109(1-2):84-94.
2002: Korach Kenneth S
Has it really been five years already?
Endocrinology 2002;143(12):i-ii.
2002: Hall Julie M; Korach Kenneth S
Analysis of the molecular mechanisms of human estrogen receptors alpha and beta reveals differential specificity in target promoter regulation by xenoestrogens.
The Journal of biological chemistry 2002;277(46):44455-61.
2002: Jefferson Wendy N; Couse John F; Padilla-Banks Elizabeth; Korach Kenneth S; Newbold Retha R
Neonatal exposure to genistein induces estrogen receptor (ER)alpha expression and multioocyte follicles in the maturing mouse ovary: evidence for ERbeta-mediated and nonestrogenic actions.
Biology of reproduction 2002;67(4):1285-96.
2002: Curtis Hewitt Sylvia; Goulding Eugenia H; Eddy E M; Korach Kenneth S
Studies using the estrogen receptor alpha knockout uterus demonstrate that implantation but not decidualization-associated signaling is estrogen dependent.
Biology of reproduction 2002;67(4):1268-77.
2002: Hewitt Sylvia Curtis; Korach Kenneth S
Estrogen receptors: structure, mechanisms and function.
Reviews in endocrine & metabolic disorders 2002;3(3):193-200.
2002: Swope Deborah l; Harrell J Chuck; Mahato Dipak; Korach Kenneth S
Genomic structure and identification of a truncated variant message of the mouse estrogen receptor alpha gene.
Gene 2002;294(1-2):239-47.
2002: Davis Vicki L; Chan Chi-Chao; Schoen Timothy J; Couse John F; Chader Gerald J; Korach Kenneth S
An estrogen receptor repressor induces cataract formation in transgenic mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(14):9427-32.
2002: Mueller Stefan O; Clark James A; Myers Page H; Korach Kenneth S
Mammary gland development in adult mice requires epithelial and stromal estrogen receptor alpha.
Endocrinology 2002;143(6):2357-65.
2002: Hewitt Sylvia Curtis; Bocchinfuso Wayne P; Zhai Jun; Harrell Chuck; Koonce Linwood; Clark James; Myers Page; Korach Kenneth S
Lack of ductal development in the absence of functional estrogen receptor alpha delays mammary tumor formation induced by transgenic expression of ErbB2/neu.
Cancer research 2002;62(10):2798-805.
2002: Nomura Masayoshi; Durbak Larissa; Chan Johnny; Smithies Oliver; Gustafsson Jan-Ake; Korach Kenneth S; Pfaff Donald W; Ogawa Sonoko
Genotype/age interactions on aggressive behavior in gonadally intact estrogen receptor beta knockout (betaERKO) male mice.
Hormones and behavior 2002;41(3):288-96.
2002: Jarred Renea A; McPherson Stephen J; Bianco Joseph J; Couse John F; Korach Kenneth S; Risbridger Gail P
Prostate phenotypes in estrogen-modulated transgenic mice.
Trends in endocrinology and metabolism: TEM 2002;13(4):163-8.
2002: Hall Julie M; McDonnell Donald P; Korach Kenneth S
Allosteric regulation of estrogen receptor structure, function, and coactivator recruitment by different estrogen response elements.
Molecular endocrinology (Baltimore, Md.) 2002;16(3):469-86.
2002: Klotz Diane M; Hewitt Sylvia Curtis; Ciana Paolo; Raviscioni Michele; Lindzey Jonathan K; Foley Julie; Maggi Adriana; DiAugustine Richard P; Korach Kenneth S
Requirement of estrogen receptor-alpha in insulin-like growth factor-1 (IGF-1)-induced uterine responses and in vivo evidence for IGF-1/estrogen receptor cross-talk.
The Journal of biological chemistry 2002;277(10):8531-7.
2002: Swope Deborah L; Castranio Trisha; Harrell J Chuck; Mishina Yuji; Korach Kenneth S
AF-2 knock-in mutation of estrogen receptor alpha: Cre-loxP excision of a PGK-neo cassette from the 3' UTR.
Genesis (New York, N.Y. : 2000) 2002;32(2):99-101.
2002: Pendaries C; Darblade B; Rochaix P; Krust A; Chambon P; Korach K S; Bayard F; Arnal J F
The AF-1 activation-function of ERalpha may be dispensable to mediate the effect of estradiol on endothelial NO production in mice.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(4):2205-10.
2001: Couse J F; Korach K S
Contrasting phenotypes in reproductive tissues of female estrogen receptor null mice.
Annals of the New York Academy of Sciences 2001;948():1-8.
2001: Emmen J M; Korach K S
Developing animal models for analyzing SERM activity.
Annals of the New York Academy of Sciences 2001;949():36-43.
2001: Levin-Allerhand J; McEwen B S; Lominska C E; Lubahn D B; Korach K S; Smith J D
Brain region-specific up-regulation of mouse apolipoprotein E by pharmacological estrogen treatments.
Journal of neurochemistry 2001;79(4):796-803.
2001: Couse J F; Dixon D; Yates M; Moore A B; Ma L; Maas R; Korach K S
Estrogen receptor-alpha knockout mice exhibit resistance to the developmental effects of neonatal diethylstilbestrol exposure on the female reproductive tract.
Developmental biology 2001;238(2):224-38.
2001: Hall J M; Couse J F; Korach K S
The multifaceted mechanisms of estradiol and estrogen receptor signaling.
The Journal of biological chemistry 2001;276(40):36869-72.
2001: Devanesan P; Santen R J; Bocchinfuso W P; Korach K S; Rogan E G; Cavalieri E
Catechol estrogen metabolites and conjugates in mammary tumors and hyperplastic tissue from estrogen receptor-alpha knock-out (ERKO)/Wnt-1 mice: implications for initiation of mammary tumors.
Carcinogenesis 2001;22(9):1573-6.
2001: Mueller S O; Korach K S
Immortalized testis cell lines from estrogen receptor (ER) alpha knock-out and wild-type mice expressing functional ERalpha or ERbeta.
Journal of andrology 2001;22(4):652-64.
2001: Mahato D; Goulding E H; Korach K S; Eddy E M
Estrogen receptor-alpha is required by the supporting somatic cells for spermatogenesis.
Molecular and cellular endocrinology 2001;178(1-2):57-63.
2001: Hodgin J B; Krege J H; Reddick R L; Korach K S; Smithies O; Maeda N
Estrogen receptor alpha is a major mediator of 17beta-estradiol's atheroprotective effects on lesion size in Apoe-/- mice.
The Journal of clinical investigation 2001;107(3):333-40.
2001: Couse J E; Mahato D; Eddy E M; Korach K S
Molecular mechanism of estrogen action in the male: insights from the estrogen receptor null mice.
Reproduction, fertility, and development 2001;13(4):211-9.
2000: Ogawa S; Chester A E; Hewitt S C; Walker V R; Gustafsson J A; Smithies O; Korach K S; Pfaff D W
Abolition of male sexual behaviors in mice lacking estrogen receptors alpha and beta (alpha beta ERKO).
Proceedings of the National Academy of Sciences of the United States of America 2000;97(26):14737-41.
2000: Couse J F; Curtis Hewitt S; Korach K S
Receptor null mice reveal contrasting roles for estrogen receptor alpha and beta in reproductive tissues.
The Journal of steroid biochemistry and molecular biology 2000;74(5):287-96.
2000: Alves S E; McEwen B S; Hayashi S; Korach K S; Pfaff D W; Ogawa S
Estrogen-regulated progestin receptors are found in the midbrain raphe but not hippocampus of estrogen receptor alpha (ER alpha) gene-disrupted mice.
The Journal of comparative neurology 2000;427(2):185-95.
2000: Hewitt S C; Korach K S
Progesterone action and responses in the alphaERKO mouse.
Steroids 2000;65(10-11):551-7.
2000: Klotz D M; Hewitt S C; Korach K S; Diaugustine R P
Activation of a uterine insulin-like growth factor I signaling pathway by clinical and environmental estrogens: requirement of estrogen receptor-alpha.
Endocrinology 2000;141(9):3430-9.
2000: Bocchinfuso W P; Lindzey J K; Hewitt S C; Clark J A; Myers P H; Cooper R; Korach K S
Induction of mammary gland development in estrogen receptor-alpha knockout mice.
Endocrinology 2000;141(8):2982-94.
2000: Migliaccio S; Newbold R R; Teti A; Jefferson W J; Toverud S U; Taranta A; Bullock B C; Suggs C A; Spera G; Korach K S
Transient estrogen exposure of female mice during early development permanently affects osteoclastogenesis in adulthood.
Bone 2000;27(1):47-52.
2000: Mahato D; Goulding E H; Korach K S; Eddy E M
Spermatogenic cells do not require estrogen receptor-alpha for development or function.
Endocrinology 2000;141(3):1273-6.
2000: Jefferson W N; Couse J F; Banks E P; Korach K S; Newbold R R
Expression of estrogen receptor beta is developmentally regulated in reproductive tissues of male and female mice.
Biology of reproduction 2000;62(2):310-7.
2000: Korach K S
Estrogen receptor knock-out mice: molecular and endocrine phenotypes.
Journal of the Society for Gynecologic Investigation 2000;7(1 Suppl):S16-7.
2000: Curtis Hewitt S; Couse J F; Korach K S
Estrogen receptor transcription and transactivation: Estrogen receptor knockout mice: what their phenotypes reveal about mechanisms of estrogen action.
Breast cancer research : BCR 2000;2(5):345-52.
1999: Karas R H; Hodgin J B; Kwoun M; Krege J H; Aronovitz M; Mackey W; Gustafsson J A; Korach K S; Smithies O; Mendelsohn M E
Estrogen inhibits the vascular injury response in estrogen receptor beta-deficient female mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(26):15133-6.
1999: Couse J F; Hewitt S C; Bunch D O; Sar M; Walker V R; Davis B J; Korach K S
Postnatal sex reversal of the ovaries in mice lacking estrogen receptors alpha and beta.
Science (New York, N.Y.) 1999;286(5448):2328-31.
1999: Couse J F; Bunch D O; Lindzey J; Schomberg D W; Korach K S
Prevention of the polycystic ovarian phenotype and characterization of ovulatory capacity in the estrogen receptor-alpha knockout mouse.
Endocrinology 1999;140(12):5855-65.
1999: Ogawa S; Chan J; Chester A E; Gustafsson J A; Korach K S; Pfaff D W
Survival of reproductive behaviors in estrogen receptor beta gene-deficient (betaERKO) male and female mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12887-92.
1999: Sueyoshi T; Yokomori N; Korach K S; Negishi M
Developmental action of estrogen receptor-alpha feminizes the growth hormone-Stat5b pathway and expression of Cyp2a4 and Cyp2d9 genes in mouse liver.
Molecular pharmacology 1999;56(3):473-7.
1999: Couse J F; Korach K S
Estrogen receptor null mice: what have we learned and where will they lead us?
Endocrine reviews 1999;20(3):358-417.
1999: Schomberg D W; Couse J F; Mukherjee A; Lubahn D B; Sar M; Mayo K E; Korach K S
Targeted disruption of the estrogen receptor-alpha gene in female mice: characterization of ovarian responses and phenotype in the adult.
Endocrinology 1999;140(6):2733-44.
1999: Bocchinfuso W P; Hively W P; Couse J F; Varmus H E; Korach K S
A mouse mammary tumor virus-Wnt-1 transgene induces mammary gland hyperplasia and tumorigenesis in mice lacking estrogen receptor-alpha.
Cancer research 1999;59(8):1869-76.
1999: Gu Q; Korach K S; Moss R L
Rapid action of 17beta-estradiol on kainate-induced currents in hippocampal neurons lacking intracellular estrogen receptors.
Endocrinology 1999;140(2):660-6.
1998: Krege J H; Hodgin J B; Couse J F; Enmark E; Warner M; Mahler J F; Sar M; Korach K S; Gustafsson J A; Smithies O
Generation and reproductive phenotypes of mice lacking estrogen receptor beta.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(26):15677-82.
1998: Ogawa S; Eng V; Taylor J; Lubahn D B; Korach K S; Pfaff D W
Roles of estrogen receptor-alpha gene expression in reproduction-related behaviors in female mice.
Endocrinology 1998;139(12):5070-81.
1998: Ogawa S; Washburn T F; Taylor J; Lubahn D B; Korach K S; Pfaff D W
Modifications of testosterone-dependent behaviors by estrogen receptor-alpha gene disruption in male mice.
Endocrinology 1998;139(12):5058-69.
1998: Migliaccio S; Washburn T F; Fillo S; Rivera H; Teti A; Korach K S; Wetsel W C
Modulation of estrogen receptor levels in mouse uterus by protein kinase C isoenzymes.
Endocrinology 1998;139(11):4598-606.
1998: Lindzey J; Wetsel W C; Couse J F; Stoker T; Cooper R; Korach K S
Effects of castration and chronic steroid treatments on hypothalamic gonadotropin-releasing hormone content and pituitary gonadotropins in male wild-type and estrogen receptor-alpha knockout mice.
Endocrinology 1998;139(10):4092-101.
1998: Sadler B R; Cho S J; Ishaq K S; Chae K; Korach K S
Three-dimensional quantitative structure-activity relationship study of nonsteroidal estrogen receptor ligands using the comparative molecular field analysis/cross-validated r2-guided region selection approach.
Journal of medicinal chemistry 1998;41(13):2261-7.
1998: Migliaccio S; Bernardini S; Wetsel W C; Korach K S; Faraggiana T; Teti A
Protein kinase C modulates estrogen receptors in differentiated osteoblastic cells in vitro.
Steroids 1998;63(5-6):352-4.
1998: Chae K; Lindzey J; McLachlan J A; Korach K S
Estrogen-dependent gene regulation by an oxidative metabolite of diethylstilbestrol, diethylstilbestrol-4',4"-quinone.
Steroids 1998;63(3):149-57.
1998: Sadler B R; Chae K; Ishaq K S; Korach K S
Separation of indenestrol A and B isomers and enantiomers by high-performance liquid chromatography.
Journal of chromatography. A 1998;799(1-2):117-24.
1997: Couse J F; Lindzey J; Grandien K; Gustafsson J A; Korach K S
Tissue distribution and quantitative analysis of estrogen receptor-alpha (ERalpha) and estrogen receptor-beta (ERbeta) messenger ribonucleic acid in the wild-type and ERalpha-knockout mouse.
Endocrinology 1997;138(11):4613-21.
1997: Bocchinfuso W P; Korach K S
Mammary gland development and tumorigenesis in estrogen receptor knockout mice.
Journal of mammary gland biology and neoplasia 1997;2(4):323-34.
1997: Couse J F; Davis V L; Hanson R B; Jefferson W N; McLachlan J A; Bullock B C; Newbold R R; Korach K S
Accelerated onset of uterine tumors in transgenic mice with aberrant expression of the estrogen receptor after neonatal exposure to diethylstilbestrol.
Molecular carcinogenesis 1997;19(4):236-42.
1997: Gandini O; Kohno H; Curtis S; Korach K S
Two transcription activation functions in the amino terminus of the mouse estrogen receptor that are affected by the carboxy terminus.
Steroids 1997;62(7):508-15.
1997: Carani C; Qin K; Simoni M; Faustini-Fustini M; Serpente S; Boyd J; Korach K S; Simpson E R
Effect of testosterone and estradiol in a man with aromatase deficiency.
The New England journal of medicine 1997;337(2):91-5.
1997: Curtis S W; Shi H; Teng C; Korach K S
Promoter and species specific differential estrogen-mediated gene transcription in the uterus and cultured cells using structurally altered agonists.
Journal of molecular endocrinology 1997;18(3):203-11.
1997: Scully K M; Gleiberman A S; Lindzey J; Lubahn D B; Korach K S; Rosenfeld M G
Role of estrogen receptor-alpha in the anterior pituitary gland.
Molecular endocrinology (Baltimore, Md.) 1997;11(6):674-81.
1997: Lindzey J; Korach K S
Developmental and physiological effects of estrogen receptor gene disruption in mice.
Trends in endocrinology and metabolism: TEM 1997;8(4):137-45.
1997: Iafrati M D; Karas R H; Aronovitz M; Kim S; Sullivan T R; Lubahn D B; O'Donnell T F; Korach K S; Mendelsohn M E
Estrogen inhibits the vascular injury response in estrogen receptor alpha-deficient mice.
Nature medicine 1997;3(5):545-8.
1997: Bocchinfuso W P; Korach K S
Estrogen receptor residues required for stereospecific ligand recognition and activation.
Molecular endocrinology (Baltimore, Md.) 1997;11(5):587-94.
1997: Ogawa S; Lubahn D B; Korach K S; Pfaff D W
Behavioral effects of estrogen receptor gene disruption in male mice.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(4):1476-81.
1997: Rissman E F; Early A H; Taylor J A; Korach K S; Lubahn D B
Estrogen receptors are essential for female sexual receptivity.
Endocrinology 1997;138(1):507-10.
1996: Ogawa S; Taylor J A; Lubahn D B; Korach K S; Pfaff D W
Reversal of sex roles in genetic female mice by disruption of estrogen receptor gene.
Neuroendocrinology 1996;64(6):467-70.
1996: Eddy E M; Washburn T F; Bunch D O; Goulding E H; Gladen B C; Lubahn D B; Korach K S
Targeted disruption of the estrogen receptor gene in male mice causes alteration of spermatogenesis and infertility.
Endocrinology 1996;137(11):4796-805.
1996: Curtis S W; Washburn T; Sewall C; DiAugustine R; Lindzey J; Couse J F; Korach K S
Physiological coupling of growth factor and steroid receptor signaling pathways: estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(22):12626-30.
1996: Kohno H; Bocchinfuso W P; Gandini O; Curtis S W; Korach K S
Mutational analysis of the estrogen receptor ligand-binding domain: influence of ligand structure and stereochemistry on transactivation.
Journal of molecular endocrinology 1996;16(3):277-85.
1996: Migliaccio S; Newbold R R; Bullock B C; Jefferson W J; Sutton F G; McLachlan J A; Korach K S
Alterations of maternal estrogen levels during gestation affect the skeleton of female offspring.
Endocrinology 1996;137(5):2118-25.
1996: Ignar-Trowbridge D M; Pimentel M; Parker M G; McLachlan J A; Korach K S
Peptide growth factor cross-talk with the estrogen receptor requires the A/B domain and occurs independently of protein kinase C or estradiol.
Endocrinology 1996;137(5):1735-44.
1996: Donaldson K M; Tong S Y; Washburn T; Lubahn D B; Eddy E M; Hutson J M; Korach K S
Morphometric study of the gubernaculum in male estrogen receptor mutant mice.
Journal of andrology 1996;17(2):91-5.
1996: Korach K S; Couse J F; Curtis S W; Washburn T F; Lindzey J; Kimbro K S; Eddy E M; Migliaccio S; Snedeker S M; Lubahn D B; Schomberg D W; Smith E P
Estrogen receptor gene disruption: molecular characterization and experimental and clinical phenotypes.
Recent progress in hormone research 1996;51():159-86; discussion 186-8.
1995: Couse J F; Curtis S W; Washburn T F; Eddy E M; Schomberg D W; Korach K S
Disruption of the mouse oestrogen receptor gene: resulting phenotypes and experimental findings.
Biochemical Society transactions 1995;23(4):929-35.
1995: Couse J F; Curtis S W; Washburn T F; Lindzey J; Golding T S; Lubahn D B; Smithies O; Korach K S
Analysis of transcription and estrogen insensitivity in the female mouse after targeted disruption of the estrogen receptor gene.
Molecular endocrinology (Baltimore, Md.) 1995;9(11):1441-54.
1995: Migliaccio S; Newbold R R; McLachlan J A; Korach K S
Alterations in estrogen levels during development affects the skeleton: use of an animal model.
Environmental health perspectives 1995;103 Suppl 7():95-7.
1995: Korach K S; McLachlan J A
Techniques for detection of estrogenicity.
Environmental health perspectives 1995;103 Suppl 7():5-8.
1995: Ignar-Trowbridge D M; Pimentel M; Teng C T; Korach K S; McLachlan J A
Cross talk between peptide growth factor and estrogen receptor signaling systems.
Environmental health perspectives 1995;103 Suppl 7():35-8.
1994: Korach K S
Insights from the study of animals lacking functional estrogen receptor.
Science (New York, N.Y.) 1994;266(5190):1524-7.
1994: Couse J F; Davis V L; Tally W C; Korach K S
An improved method of genomic DNA extraction for screening transgenic mice.
BioTechniques 1994;17(6):1030-2.
1994: Kohno H; Gandini O; Curtis S W; Korach K S
Anti-estrogen activity in the yeast transcription system: estrogen receptor mediated agonist response.
Steroids 1994;59(10):572-8.
1994: Davis V L; Couse J F; Goulding E H; Power S G; Eddy E M; Korach K S
Aberrant reproductive phenotypes evident in transgenic mice expressing the wild-type mouse estrogen receptor.
Endocrinology 1994;135(1):379-86.
1994: Davis V L; Couse J F; Gray T K; Korach K S
Correlation between low levels of estrogen receptors and estrogen responsiveness in two rat osteoblast-like cell lines.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(7):983-91.
1994: Goyer R A; Epstein S; Bhattacharyya M; Korach K S; Pounds J
Environmental risk factors for osteoporosis.
Environmental health perspectives 1994;102(4):390-4.
1993: Lubahn D B; Moyer J S; Golding T S; Couse J F; Korach K S; Smithies O
Alteration of reproductive function but not prenatal sexual development after insertional disruption of the mouse estrogen receptor gene.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(23):11162-6.
1993: Holladay S D; Blaylock B L; Comment C E; Heindel J J; Fox W M; Korach K S; Luster M I
Selective prothymocyte targeting by prenatal diethylstilbesterol exposure.
Cellular immunology 1993;152(1):131-42.
1993: Migliaccio S; Wetsel W C; Fox W M; Washburn T F; Korach K S
Endogenous protein kinase-C activation in osteoblast-like cells modulates responsiveness to estrogen and estrogen receptor levels.
Molecular endocrinology (Baltimore, Md.) 1993;7(9):1133-43.
1993: Ignar-Trowbridge D M; Teng C T; Ross K A; Parker M G; Korach K S; McLachlan J A
Peptide growth factors elicit estrogen receptor-dependent transcriptional activation of an estrogen-responsive element.
Molecular endocrinology (Baltimore, Md.) 1993;7(8):992-8.
1993: Ikeda M; Ogata F; Curtis S W; Lubahn D B; French F S; Wilson E M; Korach K S
Characterization of the DNA-binding domain of the mouse uterine estrogen receptor using site-specific polyclonal antibodies.
The Journal of biological chemistry 1993;268(14):10296-302.
1992: Hébert C D; Endo S; Korach K S; Boyd J; Barrett J C; McLachlan J A; Newbold R R
Characterization of murine cell lines from diethylstilbestrol-induced uterine endometrial adenocarcinomas.
In vitro cellular & developmental biology : journal of the Tissue Culture Association 1992;28A(5):327-36.
1992: Ignar-Trowbridge D M; Nelson K G; Bidwell M C; Curtis S W; Washburn T F; McLachlan J A; Korach K S
Coupling of dual signaling pathways: epidermal growth factor action involves the estrogen receptor.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(10):4658-62.
1992: Migliaccio S; Davis V L; Gibson M K; Gray T K; Korach K S
Estrogens modulate the responsiveness of osteoblast-like cells (ROS 17/2.8) stably transfected with estrogen receptor.
Endocrinology 1992;130(5):2617-24.
1992: Migliaccio S; Newbold R R; Bullock B C; McLachlan J A; Korach K S
Developmental exposure to estrogens induces persistent changes in skeletal tissue.
Endocrinology 1992;130(3):1756-8.
1991: Chae K; Gibson M K; Korach K S
Estrogen receptor stereochemistry: ligand binding orientation and influence on biological activity.
Molecular pharmacology 1991;40(5):806-11.
1991: Ignar-Trowbridge D M; Hughes A R; Putney J W; McLachlan J A; Korach K S
Diethylstilbestrol stimulates persistent phosphatidylinositol lipid turnover by an estrogen receptor-mediated mechanism in immature mouse uterus.
Endocrinology 1991;129(5):2423-30.
1991: Gibson M K; Nemmers L A; Beckman W C; Davis V L; Curtis S W; Korach K S
The mechanism of ICI 164,384 antiestrogenicity involves rapid loss of estrogen receptor in uterine tissue.
Endocrinology 1991;129(4):2000-10.
1991: Ignar-Trowbridge D M; Nelson K G; Ross K A; Washburn T F; Korach K S; McLachlan J A
Localization of the estrogen receptor in uterine cells by affinity labeling with [3H]tamoxifen aziridine.
The Journal of steroid biochemistry and molecular biology 1991;39(1):131-2.
1991: Curtis S W; Korach K S
Uterine estrogen receptor-DNA complexes: effects of different ERE sequences, ligands, and receptor forms.
Molecular endocrinology (Baltimore, Md.) 1991;5(7):959-66.
1991: Korach K S; Chae K; Gibson M; Curtis S
Estrogen receptor stereochemistry: ligand binding and hormonal responsiveness.
Steroids 1991;56(5):263-70.
1991: Metzger D A; Curtis S; Korach K S
Diethylstilbestrol metabolites and analogs: differential ligand effects on estrogen receptor interactions with nuclear matrix sites.
Endocrinology 1991;128(4):1785-91.
1991: Washburn T; Hocutt A; Brautigan D L; Korach K S
Uterine estrogen receptor in vivo: phosphorylation of nuclear specific forms on serine residues.
Molecular endocrinology (Baltimore, Md.) 1991;5(2):235-42.
1991: Chae K; Johnston S H; Korach K S
Multiple estrogen binding sites in the uterus: stereochemistry of receptor and non-receptor binding of diethylstilbestrol and its metabolites.
The Journal of steroid biochemistry and molecular biology 1991;38(1):35-42.
1990: Yamashita S; Newbold R R; McLachlan J A; Korach K S
The role of the estrogen receptor in uterine epithelial proliferation and cytodifferentiation in neonatal mice.
Endocrinology 1990;127(5):2456-63.
1990: Metzger D A; Korach K S
Cell-free interaction of the estrogen receptor with mouse uterine nuclear matrix: evidence of saturability, specificity, and resistance to KCl extraction.
Endocrinology 1990;126(4):2190-5.
1990: Curtis S W; Korach K S
Uterine estrogen receptor interaction with estrogen-responsive DNA sequences in vitro: effects of ligand binding on receptor-DNA complexes.
Molecular endocrinology (Baltimore, Md.) 1990;4(2):276-86.
1989: Yamashita S; Newbold R R; McLachlan J A; Korach K S
Developmental pattern of estrogen receptor expression in female mouse genital tracts.
Endocrinology 1989;125(6):2888-96.
1989: Yamashita S; Korach K S
Immunological analysis of the biochemical properties of the uterine estrogen receptor.
Biology of reproduction 1989;40(6):1275-85.
1989: Korach K S; Chae K; Levy L A; Duax W L; Sarver P J
Diethylstilbestrol metabolites and analogs. Stereochemical probes for the estrogen receptor binding site.
The Journal of biological chemistry 1989;264(10):5642-7.
1988: Horigome T; Ogata F; Golding T S; Korach K S
Estradiol-stimulated proteolytic cleavage of the estrogen receptor in mouse uterus.
Endocrinology 1988;123(5):2540-8.
1988: DiAugustine R P; Petrusz P; Bell G I; Brown C F; Korach K S; McLachlan J A; Teng C T
Influence of estrogens on mouse uterine epidermal growth factor precursor protein and messenger ribonucleic acid.
Endocrinology 1988;122(6):2355-63.
1988: Chae K; Levy L A; Korach K S
Chromatographic separation and isolation of the enantiomers of diethylstilbestrol metabolites.
Journal of chromatography 1988;439(2):484-7.
1988: Quarmby V E; Fox-Davies C; Newbold R R; Korach K S
Response of the mouse uterus to nafoxidine stimulation: agonism and antagonism.
Biology of reproduction 1988;38(4):945-54.
1988: Korach K S; Horigome T; Tomooka Y; Yamashita S; Newbold R R; McLachlan J A
Immunodetection of estrogen receptor in epithelial and stromal tissues of neonatal mouse uterus.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(10):3334-7.
1988: Golding T S; Korach K S
Nuclear estrogen receptor molecular heterogeneity in the mouse uterus.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(1):69-73.
1988: Korach K S; Sarver P; Chae K; McLachlan J A; McKinney J D
Estrogen receptor-binding activity of polychlorinated hydroxybiphenyls: conformationally restricted structural probes.
Molecular pharmacology 1988;33(1):120-6.
1987: Horigome T; Golding T S; Quarmby V E; Lubahn D B; McCarty K; Korach K S
Purification and characterization of mouse uterine estrogen receptor under conditions of varying hormonal status.
Endocrinology 1987;121(6):2099-111.
1987: Korach K S; Levy L A; Sarver P J
Estrogen receptor stereochemistry: receptor binding and hormonal responses.
Journal of steroid biochemistry 1987;27(1-3):281-90.
1985: Korach K S; Fox-Davies C; Quarmby V E; Swaisgood M H
Diethylstilbestrol metabolites and analogs. Biochemical probes for differential stimulation of uterine estrogen responses.
The Journal of biological chemistry 1985;260(29):15420-6.
1984: Quarmby V E; Fox-Davies C; Korach K S
Estrogen action in the mouse uterus: the influence of the neuroendocrine-adrenal axis.
Endocrinology 1984;114(1):108-15.
1982: Quarmby V E; Fox-Davies C; Swaisgood M H; Korach K S
Estrogen action in the mouse uterus: adrenal modulation of receptor levels.
Endocrinology 1982;110(4):1208-16.

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