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Gregory Korbutt

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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TOP 3
Korbutt Gregory S
The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 3: Pig islet product manufacturing and release testing.
Hering Bernhard J; Cooper David K C; Cozzi Emanuele; Schuurman Henk-Jan; Korbutt Gregory S; Denner Joachim; O'Connell Philip J; Vanderpool Harold Y; Pierson Richard N
The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-- executive summary.
Mallett Aaron G; Korbutt Gregory S
Alginate modification improves long-term survival and function of transplanted encapsulated islets.

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All Publications

2009: Korbutt Gregory S
The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes--chapter 3: Pig islet product manufacturing and release testing.
Xenotransplantation 2009;16(4):223-8.
2009: Hering Bernhard J; Cooper David K C; Cozzi Emanuele; Schuurman Henk-Jan; Korbutt Gregory S; Denner Joachim; O'Connell Philip J; Vanderpool Harold Y; Pierson Richard N
The International Xenotransplantation Association consensus statement on conditions for undertaking clinical trials of porcine islet products in type 1 diabetes-- executive summary.
Xenotransplantation 2009;16(4):196-202.
2009: Mallett Aaron G; Korbutt Gregory S
Alginate modification improves long-term survival and function of transplanted encapsulated islets.
Tissue engineering. Part A 2009;15(6):1301-9.
2009: Joynt Chloë; Bigam David L; Charrois Gregory; Jewell Laurence D; Korbutt Gregory; Cheung Po-Yin
Intestinal hemodynamic effects of milrinone in asphyxiated newborn pigs after reoxygenation with 100% oxygen: a dose-response study.
Shock (Augusta, Ga.) 2009;31(3):292-9.
2009: Seeberger Karen L; Eshpeter Alana; Rajotte Ray V; Korbutt Gregory S
Epithelial cells within the human pancreas do not coexpress mesenchymal antigens: epithelial-mesenchymal transition is an artifact of cell culture.
Laboratory investigation; a journal of technical methods and pathology 2009;89(2):110-21.
2009: Johnson Scott T; Bigam David L; Emara Marwan; Slack Graham; Jewell Laurence D; Obaid Laila; Korbutt Gregory; Van Aerde John; Cheung Po-Yin
Effects of N-acetylcysteine on intestinal reoxygenation injury in hypoxic newborn piglets resuscitated with 100% oxygen.
Neonatology 2009;96(3):162-70.
2008: Kin Tatsuya; O'Neil John J; Pawlick Rena; Korbutt Gregory S; Shapiro A M James; Lakey Jonathan R T
The use of an approved biodegradable polymer scaffold as a solid support system for improvement of islet engraftment.
Artificial organs 2008;32(12):990-3.
2008: Eshpeter A; Jiang J; Au M; Rajotte R V; Lu K; Lebkowski J S; Majumdar A S; Korbutt G S
In vivo characterization of transplanted human embryonic stem cell-derived pancreatic endocrine islet cells.
Cell proliferation 2008;41(6):843-58.
2008: Oosman Sarah N; Lam Ada W; Harb George; Unniappan Suraj; Lam Ni T; Webber Travis; Bruch Daniel; Zhang Qiu-Xia; Korbutt Gregory S; Kieffer Timothy J
Treatment of obesity and diabetes in mice by transplant of gut cells engineered to produce leptin.
Molecular therapy : the journal of the American Society of Gene Therapy 2008;16(6):1138-45.
2008: Korbutt Gregory S
What type of islets should be used?
Xenotransplantation 2008;15(2):81-2.
2008: Stevens Jonathan P; Churchill Thomas; Fokkelman Karien; Haase Erika; Idikio Halliday; Korbutt Gregory; Bigam David L; Cheung Po-Yin
Oxidative stress and matrix metalloproteinase-9 activity in the liver after hypoxia and reoxygenation with 21% or 100% oxygen in newborn piglets.
European journal of pharmacology 2008;580(3):385-93.
2008: Kobayashi Tsunehiro; Arefanian Hossein; Harb George; Tredget Eric B; Rajotte Ray V; Korbutt Gregory S; Rayat Gina R
Prolonged survival of microencapsulated neonatal porcine islet xenografts in immune-competent mice without antirejection therapy.
Cell transplantation 2008;17(10-11):1243-56.
2008: Dufour Jannette M; Dass Brinda; Halley Katie R; Korbutt Gregory S; Dixon Doreen E; Rajotte Ray V
Sertoli cell line lacks the immunoprotective properties associated with primary Sertoli cells.
Cell transplantation 2008;17(5):525-34.
2008: Dufour Jannette M; Lord Sarah J; Kin Tatsuya; Rayat Gina R; Dixon Doreen E; Bleackley R Chris; Korbutt Gregory S; Rajotte Ray V
Comparison of successful and unsuccessful islet/Sertoli cell cotransplant grafts in streptozotocin-induced diabetic mice.
Cell transplantation 2008;16(10):1029-38.
2007: Harb George; Toreson Jeff; Dufour Janette; Korbutt Gregory
Acute exposure to streptozotocin but not human proinflammatory cytokines impairs neonatal porcine islet insulin secretion in vitro but not in vivo.
Xenotransplantation 2007;14(6):580-90.
2007: Johnson Scott T; Bigam David L; Emara Marwan; Obaid Laila; Slack Graham; Korbutt Gregory; Jewell Laurence D; Van Aerde John; Cheung Po-Yin
N-acetylcysteine improves the hemodynamics and oxidative stress in hypoxic newborn pigs reoxygenated with 100% oxygen.
Shock (Augusta, Ga.) 2007;28(4):484-90.
2007: Jiang Jianjie; Au Melinda; Lu Kuanghui; Eshpeter Alana; Korbutt Gregory; Fisk Greg; Majumdar Anish S
Generation of insulin-producing islet-like clusters from human embryonic stem cells.
Stem cells (Dayton, Ohio) 2007;25(8):1940-53.
2007: Kin Tatsuya; Korbutt Gregory S
Delayed functional maturation of neonatal porcine islets in recipients under strict glycemic control.
Xenotransplantation 2007;14(4):333-8.
2007: Lehr Eric J; Hermary Sarah; McKay Ryan T; Webb Deryck N H; Abazari Alireza; McGann Locksley E; Coe James Y; Korbutt Gregory S; Ross David B
NMR assessment of Me(2)SO in decellularized cryopreserved aortic valve conduits.
The Journal of surgical research 2007;141(1):60-7.
2007: Fokkelman Karien; Haase Erika; Stevens Johnathan; Idikio Halliday; Korbutt Gregory; Bigam David; Cheung Po-Yin
Tissue-specific changes in glutathione content of hypoxic newborn pigs reoxygenated with 21% or 100% oxygen.
European journal of pharmacology 2007;562(1-2):132-7.
2007: Arefanian Hossein; Tredget Eric B; Rajotte Ray V; Korbutt Gregory S; Gill Ron G; Rayat Gina R
Combination of anti-CD4 with anti-LFA-1 and anti-CD154 monoclonal antibodies promotes long-term survival and function of neonatal porcine islet xenografts in spontaneously diabetic NOD mice.
Cell transplantation 2007;16(8):787-98.
2007: Lakey Jonathan R T; Kin Tatsuya; Warnock Garth L; Shapiro A M James; Tsapogas Panagiotis; Imes Sharleen; Korbutt Gregory S; Kneteman Norman M; Rajotte Ray V; Ryan Edmond A
Long-term graft function after allogeneic islet transplantation.
Cell transplantation 2007;16(4):441-6.
2006: Lehr Eric J; Rayat Gina R; Desai Leena S; Coe James Y; Korbutt Greg S; Ross David B
Inbred or outbred? An evaluation of the functional allogenicity of farm sheep used in cardiac valve studies.
The Journal of thoracic and cardiovascular surgery 2006;132(5):1156-61.
2006: Kobayashi Tsunehiro; Harb George; Rajotte Ray V; Korbutt Gregory S; Mallett Aaron G; Arefanian Hossein; Mok Dereck; Rayat Gina R
Immune mechanisms associated with the rejection of encapsulated neonatal porcine islet xenografts.
Xenotransplantation 2006;13(6):547-59.
2006: Harb George; Korbutt Gregory S
Effect of prolonged in vitro exposure to high glucose on neonatal porcine pancreatic islets.
The Journal of endocrinology 2006;191(1):37-44.
2006: Emamaullee Juliet A; Shapiro A M James; Rajotte Ray V; Korbutt Greg; Elliott John F
Neonatal porcine islets exhibit natural resistance to hypoxia-induced apoptosis.
Transplantation 2006;82(7):945-52.
2006: Sipione Simonetta; Simmen Katia C; Lord Sarah J; Motyka Bruce; Ewen Catherine; Shostak Irene; Rayat Gina R; Dufour Jannette M; Korbutt Greg S; Rajotte Ray V; Bleackley R Chris
Identification of a novel human granzyme B inhibitor secreted by cultured sertoli cells.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(8):5051-8.
2006: Bussiere C T; Lakey J R T; Shapiro A M J; Korbutt G S
The impact of the mTOR inhibitor sirolimus on the proliferation and function of pancreatic islets and ductal cells.
Diabetologia 2006;49(10):2341-9.
2006: Harb G; Heremans Y; Heimberg H; Korbutt G S
Ectopic expression of neurogenin 3 in neonatal pig pancreatic precursor cells induces (trans)differentiation to functional alpha cells.
Diabetologia 2006;49(8):1855-63.
2006: Manji Rizwan A; Zhu Lin F; Nijjar Nimrit K; Rayner David C; Korbutt Greg S; Churchill Thomas A; Rajotte Ray V; Koshal Arvind; Ross David B
Glutaraldehyde-fixed bioprosthetic heart valve conduits calcify and fail from xenograft rejection.
Circulation 2006;114(4):318-27.
2006: Cardona Kenneth; Korbutt Gregory S; Milas Zvonimir; Lyon James; Cano Jose; Jiang Wanhong; Bello-Laborn Hameeda; Hacquoil Brad; Strobert Elizabeth; Gangappa Shivaprakash; Weber Collin J; Pearson Thomas C; Rajotte Ray V; Larsen Christian P
Long-term survival of neonatal porcine islets in nonhuman primates by targeting costimulation pathways.
Nature medicine 2006;12(3):304-6.
2006: Seeberger Karen L; Dufour Jannette M; Shapiro Andrew M James; Lakey Jonathan R T; Rajotte Ray V; Korbutt Gregory S
Expansion of mesenchymal stem cells from human pancreatic ductal epithelium.
Laboratory investigation; a journal of technical methods and pathology 2006;86(2):141-53.
2006: Jiang H; Secretan C; Gao T; Bagnall K; Korbutt G; Lakey J; Jomha N M
The development of osteoblasts from stem cells to supplement fusion of the spine during surgery for AIS.
Studies in health technology and informatics 2006;123():467-72.
2005: Thébaud Bernard; Ladha Faruqa; Michelakis Evangelos D; Sawicka Monika; Thurston Gavin; Eaton Farah; Hashimoto Kyoko; Harry Gwyneth; Haromy Alois; Korbutt Greg; Archer Stephen L
Vascular endothelial growth factor gene therapy increases survival, promotes lung angiogenesis, and prevents alveolar damage in hyperoxia-induced lung injury: evidence that angiogenesis participates in alveolarization.
Circulation 2005;112(16):2477-86.
2005: Dufour Jannette M; Rajotte Ray V; Zimmerman Mark; Rezania Alireza; Kin Tatsuya; Dixon Doreen E; Korbutt Gregory S
Development of an ectopic site for islet transplantation, using biodegradable scaffolds.
Tissue engineering 2005;11(9-10):1323-31.
2005: Ladha Faruqa; Bonnet Sebastien; Eaton Farah; Hashimoto Kyoko; Korbutt Greg; Thébaud Bernard
Sildenafil improves alveolar growth and pulmonary hypertension in hyperoxia-induced lung injury.
American journal of respiratory and critical care medicine 2005;172(6):750-6.
2005: Dufour Jannette M; Hamilton Meredith; Rajotte Ray V; Korbutt Gregory S
Neonatal porcine Sertoli cells inhibit human natural antibody-mediated lysis.
Biology of reproduction 2005;72(5):1224-31.
2005: Haase Erika; Bigam David L; Nakonechny Quentin B; Rayner David; Korbutt Gregory; Cheung Po-Yin
Cardiac function, myocardial glutathione, and matrix metalloproteinase-2 levels in hypoxic newborn pigs reoxygenated by 21%, 50%, or 100% oxygen.
Shock (Augusta, Ga.) 2005;23(4):383-9.
2005: Kin Tatsuya; Korbutt Gregory S; Kobayashi Tsunehiro; Dufour Jannette M; Rajotte Ray V
Reversal of diabetes in pancreatectomized pigs after transplantation of neonatal porcine islets.
Diabetes 2005;54(4):1032-9.
2004: Street Cale N; Lakey Jonathan R T; Shapiro A M James; Imes Sharleen; Rajotte Ray V; Ryan Edmond A; Lyon James G; Kin Tatsuya; Avila Jose; Tsujimura Toshiaki; Korbutt Gregory S
Islet graft assessment in the Edmonton Protocol: implications for predicting long-term clinical outcome.
Diabetes 2004;53(12):3107-14.
2004: Korbutt G S; Mallett A G; Ao Z; Flashner M; Rajotte R V
Improved survival of microencapsulated islets during in vitro culture and enhanced metabolic function following transplantation.
Diabetologia 2004;47(10):1810-8.
2004: Kin Tatsuya; Rajotte Ray V; Korbutt Gregory S
Reassessment of the vascularization of renal subcapsular islet grafts.
Pancreas 2004;29(3):e59-63.
2004: Seaberg Raewyn M; Smukler Simon R; Kieffer Timothy J; Enikolopov Grigori; Asghar Zeenat; Wheeler Michael B; Korbutt Gregory; van der Kooy Derek
Clonal identification of multipotent precursors from adult mouse pancreas that generate neural and pancreatic lineages.
Nature biotechnology 2004;22(9):1115-24.
2004: Haase Erika; Bigam David L; Nakonechny Quentin B; Jewell Laurence D; Korbutt Gregory; Cheung Po-Yin
Resuscitation with 100% oxygen causes intestinal glutathione oxidation and reoxygenation injury in asphyxiated newborn piglets.
Annals of surgery 2004;240(2):364-73.
2004: Binette Tanya M; Seeberger Karen L; Lyon James G; Rajotte Ray V; Korbutt Gregory S
Porcine endogenous retroviral nucleic acid in peripheral tissues is associated with migration of porcine cells post islet transplant.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2004;4(7):1051-60.
2004: Leclerc Isabelle; Woltersdorf Wolfram W; da Silva Xavier Gabriela; Rowe Rebecca L; Cross Sarah E; Korbutt Greg S; Rajotte Ray V; Smith Richard; Rutter Guy A
Metformin, but not leptin, regulates AMP-activated protein kinase in pancreatic islets: impact on glucose-stimulated insulin secretion.
American journal of physiology. Endocrinology and metabolism 2004;286(6):E1023-31.
2004: Street Cale N; Sipione Simonetta; Helms Lisa; Binette Tanya; Rajotte Ray V; Bleackley R Chris; Korbutt Gregory S
Stem cell-based approaches to solving the problem of tissue supply for islet transplantation in type 1 diabetes.
The international journal of biochemistry & cell biology 2004;36(4):667-83.
2004: Dufour J M; Hemendinger R; Halberstadt C R; Gores P; Emerich D F; Korbutt G S; Rajotte R V
Genetically engineered Sertoli cells are able to survive allogeneic transplantation.
Gene therapy 2004;11(8):694-700.
2004: Sipione S; Eshpeter A; Lyon J G; Korbutt G S; Bleackley R C
Insulin expressing cells from differentiated embryonic stem cells are not beta cells.
Diabetologia 2004;47(3):499-508.
2004: Street C N; Lakey J R T; Seeberger K; Helms L; Rajotte R V; Shapiro A M J; Korbutt G S
Heterogenous expression of nestin in human pancreatic tissue precludes its use as an islet precursor marker.
The Journal of endocrinology 2004;180(2):213-25.
2004: Street Cale N; Lakey Jonathan R T; Rajotte Ray V; Shapiro A M James; Kieffer Timothy J; Lyon James G; Kin Tatsuya; Korbutt Gregory S
Enriched human pancreatic ductal cultures obtained from selective death of acinar cells express pancreatic and duodenal homeobox gene-1 age-dependently.
The review of diabetic studies : RDS 2004;1(2):66-79.
2003: Dufour Jannette M; Rajotte Ray V; Seeberger Karen; Kin Tatsuya; Korbutt Gregory S
Long-term survival of neonatal porcine Sertoli cells in non-immunosuppressed rats.
Xenotransplantation 2003;10(6):577-86.
2003: Dufour Jannette M; Rajotte Ray V; Korbutt Gregory S; Emerich Dwaine F
Harnessing the immunomodulatory properties of Sertoli cells to enable xenotransplantation in type I diabetes.
Immunological investigations 2003;32(4):275-97.
2003: Owen Richard J T; Ryan Edmond A; O'Kelly Kevin; Lakey Jonathan R T; McCarthy Mairin C; Paty Breay W; Bigam David L; Kneteman Norman M; Korbutt Gregory S; Rajotte Ray V; Shapiro A M James
Percutaneous transhepatic pancreatic islet cell transplantation in type 1 diabetes mellitus: radiologic aspects.
Radiology 2003;229(1):165-70.
2003: Rayat Gina R; Rajotte Ray V; Lyon James G; Dufour Jannette M; Hacquoil Brad V; Korbutt Gregory S
Immunization with streptozotocin-treated NOD mouse islets inhibits the onset of autoimmune diabetes in NOD mice.
Journal of autoimmunity 2003;21(1):11-5.
2003: Rayat Gina R; Johnson Zachary A; Beilke Joshua N; Korbutt Gregory S; Rajotte Ray V; Gill Ronald G
The degree of phylogenetic disparity of islet grafts dictates the reliance on indirect CD4 T-cell antigen recognition for rejection.
Diabetes 2003;52(6):1433-40.
2003: Lord Sarah J; Rajotte Ray V; Korbutt Gregory S; Bleackley R Chris
Granzyme B: a natural born killer.
Immunological reviews 2003;193():31-8.
2003: Dufour Jannette M; Rajotte Ray V; Kin Tatsuya; Korbutt Gregory S
Immunoprotection of rat islet xenografts by cotransplantation with sertoli cells and a single injection of antilymphocyte serum.
Transplantation 2003;75(9):1594-6.
2003: Rayat G R; Rajotte R V; Hering B J; Binette T M; Korbutt G S
In vitro and in vivo expression of Galalpha-(1,3)Gal on porcine islet cells is age dependent.
The Journal of endocrinology 2003;177(1):127-35.
2003: Gores Paul F; Hayes Daniel H; Copeland M Jane; Korbutt Gregory S; Halberstadt Craig; Kirkpatrick Shaun A; Rajotte Ray V
Long-term survival of intratesticular porcine islets in nonimmunosuppressed beagles.
Transplantation 2003;75(5):613-8.
2003: Manji Rizwan A; Manji Jacqueline S; Koshal Arvind; Korbutt Gregory S; Rajotte Ray V
Human ABO blood group is important in survival and function of porcine working hearts.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(3):286-93.
2003: Kin Tatsuya; Korbutt Gregory S; Rajotte Ray V
Survival and metabolic function of syngeneic rat islet grafts transplanted in the omental pouch.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2003;3(3):281-5.
2003: Street Cale N; Rajotte Ray V; Korbutt Gregory S
Stem cells: a promising source of pancreatic islets for transplantation in type 1 diabetes.
Current topics in developmental biology 2003;58():111-36.
2003: Oberholzer José; Shapiro A M; Lakey Jonathan R; Ryan Edmond A; Rajotte Ray V; Korbutt Gregory S; Morel Philippe; Kneteman Norman M
Current status of islet cell transplantation.
Advances in surgery 2003;37():253-82.
2002: Tsujimura Toshiaki; Kuroda Yoshikazu; Kin Tatsuya; Avila Jose G; Rajotte Ray V; Korbutt Gregory S; Ryan Edmond A; Shapiro A M James; Lakey Jonathan R T
Human islet transplantation from pancreases with prolonged cold ischemia using additional preservation by the two-layer (UW solution/perfluorochemical) cold-storage method.
Transplantation 2002;74(12):1687-91.
2002: Casey John J; Lakey Jonathan R; Ryan Edmond A; Paty Breay W; Owen Richard; O'Kelly Kevin; Nanji Sulaiman; Rajotte Ray V; Korbutt Gregory S; Bigam David; Kneteman Norman N; Shapiro A M
Portal venous pressure changes after sequential clinical islet transplantation.
Transplantation 2002;74(7):913-5.
2002: Dufour Jannette M; Rajotte Ray V; Korbutt Gregory S
Development of an in vivo model to study testicular morphogenesis.
Journal of andrology 2002;23(5):635-44.
2002: Ryan Edmond A; Lakey Jonathan R T; Paty Breay W; Imes Sharleen; Korbutt Gregory S; Kneteman Norman M; Bigam David; Rajotte Ray V; Shapiro A M James
Successful islet transplantation: continued insulin reserve provides long-term glycemic control.
Diabetes 2002;51(7):2148-57.
2002: Kin Tatsuya; Rajotte Ray V; Dufour Jannette M; Korbutt Gregory S
Development of an immunoprivileged site to prolong islet allograft survival.
Cell transplantation 2002;11(6):547-52.
2001: Lakey J R; Suarez-Pinzon W L; Strynadka K; Korbutt G S; Rajotte R V; Mabley J G; Szabó C; Rabinovitch A
Peroxynitrite is a mediator of cytokine-induced destruction of human pancreatic islet beta cells.
Laboratory investigation; a journal of technical methods and pathology 2001;81(12):1683-92.
2001: Binette T M; Dufour J M; Korbutt G S
In vitro maturation of neonatal porcine islets: a novel model for the study of islet development and xenotransplantation.
Annals of the New York Academy of Sciences 2001;944():47-61.
2001: Lakey J R; Helms L M; Kin T; Korbutt G S; Rajotte R V; Shapiro A M; Warnock G L
Serine-protease inhibition during islet isolation increases islet yield from human pancreases with prolonged ischemia.
Transplantation 2001;72(4):565-70.
2001: Ryan E A; Lakey J R; Rajotte R V; Korbutt G S; Kin T; Imes S; Rabinovitch A; Elliott J F; Bigam D; Kneteman N M; Warnock G L; Larsen I; Shapiro A M
Clinical outcomes and insulin secretion after islet transplantation with the Edmonton protocol.
Diabetes 2001;50(4):710-9.
2001: Fedorow C; McGann L E; Korbutt G S; Rayat G R; Rajotte R V; Lakey J R
Osmotic and cryoprotectant permeation characteristics of islet cells isolated from the newborn pig pancreas.
Cell transplantation 2001;10(7):651-9.
2000: Cheung A T; Dayanandan B; Lewis J T; Korbutt G S; Rajotte R V; Bryer-Ash M; Boylan M O; Wolfe M M; Kieffer T J
Glucose-dependent insulin release from genetically engineered K cells.
Science (New York, N.Y.) 2000;290(5498):1959-62.
2000: Suarez-Pinzon W; Korbutt G S; Power R; Hooton J; Rajotte R V; Rabinovitch A
Testicular sertoli cells protect islet beta-cells from autoimmune destruction in NOD mice by a transforming growth factor-beta1-dependent mechanism.
Diabetes 2000;49(11):1810-8.
2000: Motyka B; Korbutt G; Pinkoski M J; Heibein J A; Caputo A; Hobman M; Barry M; Shostak I; Sawchuk T; Holmes C F; Gauldie J; Bleackley R C
Mannose 6-phosphate/insulin-like growth factor II receptor is a death receptor for granzyme B during cytotoxic T cell-induced apoptosis.
Cell 2000;103(3):491-500.
2000: Rayat G R; Singh B; Korbutt G S; Rajotte R V
Single injection of insulin delays the recurrence of diabetes in syngeneic islet-transplanted diabetic NOD mice.
Transplantation 2000;70(6):976-9.
2000: Shapiro A M; Lakey J R; Ryan E A; Korbutt G S; Toth E; Warnock G L; Kneteman N M; Rajotte R V
Islet transplantation in seven patients with type 1 diabetes mellitus using a glucocorticoid-free immunosuppressive regimen.
The New England journal of medicine 2000;343(4):230-8.
2000: Korbutt G S; Suarez-Pinzon W L; Power R F; Rajotte R V; Rabinovitch A
Testicular Sertoli cells exert both protective and destructive effects on syngeneic islet grafts in non-obese diabetic mice.
Diabetologia 2000;43(4):474-80.
2000: Rayat G R; Rajotte R V; Ao Z; Korbutt G S
Microencapsulation of neonatal porcine islets: protection from human antibody/complement-mediated cytolysis in vitro and long-term reversal of diabetes in nude mice.
Transplantation 2000;69(6):1084-90.
1999: Murray A G; Nelson R C; Rayat G R; Elliott J F; Korbutt G S
Neonatal porcine islet cells induce human CD4+, but not CD8+, lymphocyte proliferation and resist cell-mediated cytolytic injury in vitro.
Diabetes 1999;48(9):1713-9.
1999: Rayat G R; Rajotte R V; Korbutt G S
Potential application of neonatal porcine islets as treatment for type 1 diabetes: a review.
Annals of the New York Academy of Sciences 1999;875():175-88.
1999: Rabinovitch A; Suarez-Pinzon W; Strynadka K; Ju Q; Edelstein D; Brownlee M; Korbutt G S; Rajotte R V
Transfection of human pancreatic islets with an anti-apoptotic gene (bcl-2) protects beta-cells from cytokine-induced destruction.
Diabetes 1999;48(6):1223-9.
1999: Lakey J R; Warnock G L; Shapiro A M; Korbutt G S; Ao Z; Kneteman N M; Rajotte R V
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.
Cell transplantation 1999;8(3):285-92.
1998: Rayat G R; Rajotte R V; Elliott J F; Korbutt G S
Expression of Gal alpha(1,3)gal on neonatal porcine islet beta-cells and susceptibility to human antibody/complement lysis.
Diabetes 1998;47(9):1406-11.
1998: Gainer A L; Suarez-Pinzon W L; Min W P; Swiston J R; Hancock-Friesen C; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Improved survival of biolistically transfected mouse islet allografts expressing CTLA4-Ig or soluble Fas ligand.
Transplantation 1998;66(2):194-9.
1998: Rønningen K S; Atrazhev A; Luo L; Luo C; Smith D K; Korbutt G; Rajotte R V; Elliott J F
Anti-BSA antibodies do not cross-react with the 69-kDa islet cell autoantigen ICA69.
Journal of autoimmunity 1998;11(3):223-31.
1998: Suarez-Pinzon W L; Korbutt G S; Rayat G; Sorensen O; Power R F; Rajotte R V; Rabinovitch A
Neonatal porcine islet xenografts in nonobese diabetic mice: effects on blood glucose and analysis of cytokines expressed in the islet grafts.
Transplantation proceedings 1998;30(2):654-5.
1998: Gainer A L; Suarez-Pinzon W L; Min W P; Hancock-Friesen C; Korbutt G S; Rajotte R V; Rabinovitch A; Warnock G L; Elliott J F
Prolongation of allograft survival of transfected islets expressing human CTLA4-Ig, human soluble Fas ligand or a combination of the two.
Transplantation proceedings 1998;30(2):534.
1998: Ao Z; Suarez-Pinzon W L; Rajotte R V; Korbutt G S; Flashner M; Rabinovitch A
Transplantation of microencapsulated syngeneic and xenogeneic (neonatal porcine) islets in nonobese diabetic mice.
Transplantation proceedings 1998;30(2):500.
1998: Korbutt G S; Ao Z; Flashner M; Elliott J F; Rajotte R V
Coencapsulation of allogeneic islets with allogeneic Sertoli cells prolongs graft survival without systemic immunosuppression.
Transplantation proceedings 1998;30(2):419.
1998: Lakey J R; Warnock G L; Ao Z; Shapiro A M; Korbutt G; Kneteman N; Rajotte R V
Intraductal collagenase delivery into the human pancreas using syringe loading or controlled perfusion.
Transplantation proceedings 1998;30(2):359.
1998: Rayat G R; Rajotte R V; Elliott J F; Korbutt G S
Gal alpha(1,3)Gal expression on neonatal porcine islet cells and susceptibility to human antibody/complement lysis.
Transplantation proceedings 1998;30(2):325.
1997: Korbutt G S; Ao Z; Flashner M; Rajotte R V
Neonatal porcine islets as a possible source of tissue for humans and microencapsulation improves the metabolic response of islet graft posttransplantation.
Annals of the New York Academy of Sciences 1997;831():294-303.
1997: Rayat G R; Korbutt G S; Elliott J F; Rajotte R V
Survival and function of syngeneic rat islet grafts placed within the thymus versus under the kidney capsule.
Cell transplantation 1997;6(6):597-602.
1997: Korbutt G S; Rayat G R; Ezekowitz J; Rajotte R V
Cryopreservation of rat pancreatic islets: effect of ethylene glycol on islet function and cellular composition.
Transplantation 1997;64(7):1065-70.
1997: Smith D K; Korbutt G S; Suarez-Pinzon W L; Kao D; Rajotte R V; Elliott J F
Interleukin-4 or interleukin-10 expressed from adenovirus-transduced syngeneic islet grafts fails to prevent beta cell destruction in diabetic NOD mice.
Transplantation 1997;64(7):1040-9.
1997: Weber C J; Hagler M K; Chryssochoos J T; Kapp J A; Korbutt G S; Rajotte R V; Linsley P S
CTLA4-Ig prolongs survival of microencapsulated neonatal porcine islet xenografts in diabetic NOD mice.
Cell transplantation 1997;6(5):505-8.
1997: Korbutt G S; Elliott J F; Ao Z; Flashner M; Warnock G L; Rajotte R V
Microencapsulation of neonatal porcine islets: long-term reversal of diabetes in nude mice and in vitro protection from human complement mediated cytolysis.
Transplantation proceedings 1997;29(4):2128.
1997: Korbutt G S; Ezekowitz J; Rajotte M M; Rayat G; Rajotte R V
Successful cryopreservation of rat islets using ethylene glycol.
Transplantation proceedings 1997;29(4):1983.
1997: Gainer A L; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Expression of CTLA4-Ig by biolistically transfected mouse islets promotes islet allograft survival.
Transplantation 1997;63(7):1017-21.
1997: Korbutt G S; Elliott J F; Rajotte R V
Cotransplantation of allogeneic islets with allogeneic testicular cell aggregates allows long-term graft survival without systemic immunosuppression.
Diabetes 1997;46(2):317-22.
1997: Korbutt G S; Warlock G L; Rajotte R V
Islet transplantation.
Advances in experimental medicine and biology 1997;426():397-410.
1996: Gainer A L; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Successful biolistic transformation of mouse pancreatic islets while preserving cellular function.
Transplantation 1996;61(11):1567-71.
1996: Korbutt G S; Elliott J F; Ao Z; Smith D K; Warnock G L; Rajotte R V
Large scale isolation, growth, and function of porcine neonatal islet cells.
The Journal of clinical investigation 1996;97(9):2119-29.
1996: Korbutt G S; Aspeslet L; Ao Z; Warnock G L; Ezekowitz J; Koshal A; Rajotte R V; Yatscoff R W
Porcine islet cell antigens are recognized by xenoreactive natural human antibodies of both IgG and IgM subtypes.
Transplantation proceedings 1996;28(2):837-8.
1995: Korbutt G S; Smith D K; Rajotte R V; Elliott J F
Expression of beta-galactosidase in mouse pancreatic islets by adenoviral-mediated gene transfer.
Transplantation proceedings 1995;27(6):3414.
1995: Rajotte R V; Ao Z; Korbutt G S; Lakey J R; Flashner M; Colby C B; Warnock G L
Cryopreservation of microencapsulated canine islets.
Transplantation proceedings 1995;27(6):3389.
1995: Ao Z; Korbutt G S; Warnock G L; Flashner M; Colby C B; Rajotte R V
Microencapsulation enhances canine islet survival during long-term culture.
Transplantation proceedings 1995;27(6):3350.
1995: Ao Z; Korbutt G S; Warnock G L; Flashner M; Colby C B; Luskey K L; Rajotte R V
Microencapsulation improves canine islet survival in vivo.
Transplantation proceedings 1995;27(6):3349.
1995: Gainer A L; Korbutt G S; Rajotte R V; Warnock G L; Elliott J F
Biolistic transformation of pancreatic islets.
Transplantation proceedings 1995;27(6):3278.
1995: Korbutt G S; Ao Z; Warnock G L; Rajotte R V
Large-scale isolation of viable porcine neonatal islet cell (NIC) aggregates.
Transplantation proceedings 1995;27(6):3267.
1995: Lakey J R; Ao Z; Warnock G L; Korbutt G S; Flashner M; Colby C B; Rajotte R V
Recovery and in vivo function of canine islets cryopreserved in a freezer bag.
Transplantation proceedings 1995;27(6):3266.
1995: Korbutt G S; Ao Z; Warnock G L; Flashner M; Rajotte R V
Successful reversal of diabetes in nude mice by transplantation of microencapsulated porcine neonatal islet cell aggregates.
Transplantation proceedings 1995;27(6):3212.
1995: Warnock G I; Tsapogas P; Ryan E A; Lakey J R; Korbutt G; Kneteman N M; Ao Z; Rabinovitch A; Rajotte R V
Natural history of insulin independence after transplantation of multidonor cryopreserved pancreatic islets in type 1 diabetic humans.
Transplantation proceedings 1995;27(6):3159-60.

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