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Gary Koretzky

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Rohan P Joshi; Gary A Koretzky
Diacylglycerol kinases: regulated controllers of T cell activation, function, and development.
Mónica Martínez-Moreno; Isabel Mérida; Denise Soutar; Pedro Torres-Ayuso; Xiao-Ping Zhong; Elena Andrada; Job García-Liévana; Gary A Koretzky; Antonia Avila-Flores
FoxO-dependent regulation of diacylglycerol kinase α gene expression.
Dooyoung Lee; Rebecca G Baker; Jiyeon Kim; Gary A Koretzky; Daniel A Hammer
SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.

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All Publications

2013: Rohan P Joshi; Gary A Koretzky
Diacylglycerol kinases: regulated controllers of T cell activation, function, and development.
International journal of molecular sciences 2013;14(4):6649-73.
2012: Mónica Martínez-Moreno; Isabel Mérida; Denise Soutar; Pedro Torres-Ayuso; Xiao-Ping Zhong; Elena Andrada; Job García-Liévana; Gary A Koretzky; Antonia Avila-Flores
FoxO-dependent regulation of diacylglycerol kinase α gene expression.
Molecular and cellular biology 2012;32(20):4168-80.
2012: Dooyoung Lee; Rebecca G Baker; Jiyeon Kim; Gary A Koretzky; Daniel A Hammer
SLP-76 is required for optimal CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.
European journal of immunology 2012;42(10):2736-43.
2012: Dooyoung Lee; Michael T Beste; Jiyeon Kim; Gary A Koretzky; Daniel A Hammer
Diacylglycerol kinase zeta negatively regulates CXCR4-stimulated T lymphocyte firm arrest to ICAM-1 under shear flow.
Integrative biology : quantitative biosciences from nano to macro 2012;4(6):606-14.
2012: Ekaterina Bobrovnikova-Marjon; Gary A Koretzky; Dariusz Pytel; Matthew J Riese; Nickpreet Singh; Laura Pontano Vaites; Eric S Witze; J Alan Diehl
PERK utilizes intrinsic lipid kinase activity to generate phosphatidic acid, mediate Akt activation, and promote adipocyte differentiation.
Molecular and cellular biology 2012;32(12):2268-78.
2012: Michael T Beste; Michael R King; Gary A Koretzky; Dooyoung Lee; Daniel A Hammer
An integrated stochastic model of "inside-out" integrin activation and selective T-lymphocyte recruitment.
Langmuir : the ACS journal of surfaces and colloids 2012;28(4):2225-37.
2011: Jeremy C Burns; Evann Corbo; Janine Degen; Mercy Gohil; Stefanie Kliche; Gary A Koretzky; Burkhart Schraven; Christine Anterasian; Martha S Jordan
The SLP-76 Src homology 2 domain is required for T cell development and activation.
Journal of immunology (Baltimore, Md. : 1950) 2011;187(9):4459-66.
2011: Jiyeon S Kim; Gary A Koretzky; Jennifer E Smith-Garvin; Martha S Jordan
The requirements for natural Th17 cell development are distinct from those of conventional Th17 cells.
The Journal of experimental medicine 2011;208(11):2201-7.
2011: Edward M Behrens; Scott W Canna; Katharine Slade; Sheila Rao; Portia A Kreiger; Michele Paessler; Taku Kambayashi; Gary A Koretzky
Repeated TLR9 stimulation results in macrophage activation syndrome-like disease in mice.
The Journal of clinical investigation 2011;121(6):2264-77.
2011: John T Chang; Maria L Ciocca; Ichiko Kinjyo; Vikram R Palanivel; Courtney E McClurkin; Caitlin S Dejong; Erin C Mooney; Jiyeon S Kim; Natalie C Steinel; Jane Oliaro; Catherine C Yin; Bogdan I Florea; Herman S Overkleeft; Leslie J Berg; Sarah M Russell; Gary A Koretzky; Martha S Jordan; Steven L Reiner
Asymmetric proteasome segregation as a mechanism for unequal partitioning of the transcription factor T-bet during T lymphocyte division.
Immunity 2011;34(4):492-504.
2011: Scott M Gordon; Shannon A Carty; Jiyeon S Kim; Tao Zou; Jennifer Smith-Garvin; Eric S Alonzo; Ethan Haimm; Derek B Sant'Angelo; Gary A Koretzky; Steven L Reiner; Martha S Jordan
Requirements for eomesodermin and promyelocytic leukemia zinc finger in the development of innate-like CD8+ T cells.
Journal of immunology (Baltimore, Md. : 1950) 2011;186(8):4573-8.
2011: Matthew J Riese; Jashanpreet Grewal; Jayajit Das; Tao Zou; Vineet Patil; Arup K Chakraborty; Gary A Koretzky
Decreased diacylglycerol metabolism enhances ERK activation and augments CD8+ T cell functional responses.
The Journal of biological chemistry 2011;286(7):5254-65.
2010: Jennifer E Smith-Garvin; Jeremy C Burns; Mercy Gohil; Tao Zou; Jiyeon S Kim; Jonathan S Maltzman; E John Wherry; Gary A Koretzky; Martha S Jordan
T-cell receptor signals direct the composition and function of the memory CD8+ T-cell pool.
Blood 2010;116(25):5548-59.
2010: Tao Zou; Rebecca M May; Gary A Koretzky
Understanding signal integration through targeted mutations of an adapter protein.
FEBS letters 2010;584(24):4901-9.
2010: Gary A Koretzky
Multiple roles of CD4 and CD8 in T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(5):2643-4.
2010: Tao Zou; Andrew J Caton; Gary A Koretzky; Taku Kambayashi
Dendritic cells induce regulatory T cell proliferation through antigen-dependent and -independent interactions.
Journal of immunology (Baltimore, Md. : 1950) 2010;185(5):2790-9.
2010: Taku Kambayashi; Mariko Okumura; Rebecca G Baker; Chih-Jung Hsu; Tobias Baumgart; Weiguo Zhang; Gary A Koretzky
Independent and cooperative roles of adaptor molecules in proximal signaling during FcepsilonRI-mediated mast cell activation.
Molecular and cellular biology 2010;30(17):4188-96.
2010: Cara C Bertozzi; Alec A Schmaier; Patricia Mericko; Paul R Hess; Zhiying Zou; Mei Chen; Chiu-Yu Chen; Bin Xu; Min Min Lu; Diane Zhou; Eric Sebzda; Matthew T Santore; Demetri J Merianos; Matthias Stadtfeld; Alan W Flake; Thomas Graf; Radek Skoda; Jonathan S Maltzman; Gary A Koretzky; Mark L Kahn
Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling.
Blood 2010;116(4):661-70.
2010: Marisa M Juntilla; Vineet D Patil; Marco Calamito; Rohan P Joshi; Morris J Birnbaum; Gary A Koretzky
AKT1 and AKT2 maintain hematopoietic stem cell function by regulating reactive oxygen species.
Blood 2010;115(20):4030-8.
2010: Marco Calamito; Marisa M Juntilla; Matthew Thomas; Daniel L Northrup; Jeffrey C Rathmell; Morris J Birnbaum; Gary A Koretzky; David Allman
Akt1 and Akt2 promote peripheral B-cell maturation and survival.
Blood 2010;115(20):4043-50.
2010: Martha S Jordan; Gary A Koretzky
Coordination of receptor signaling in multiple hematopoietic cell lineages by the adaptor protein SLP-76.
Cold Spring Harbor perspectives in biology 2010;2(4):a002501.
2010: Gregory F Sonnenberg; Paul R Mangan; Natalie A Bezman; Debora R Sekiguchi; Eline T Luning Prak; Jan Erikson; Jonathan S Maltzman; Martha S Jordan; Gary A Koretzky
Mislocalization of SLP-76 leads to aberrant inflammatory cytokine and autoantibody production.
Blood 2010;115(11):2186-95.
2010: Austin T Thiel; Peter Blessington; Tao Zou; Danielle Feather; Xinjiang Wu; Jizhou Yan; Hui Zhang; Zuguo Liu; Patricia Ernst; Gary A Koretzky; Xianxin Hua
MLL-AF9-induced leukemogenesis requires coexpression of the wild-type Mll allele.
Cancer cell 2010;17(2):148-59.
2010: Eric S Alonzo; Rachel A Gottschalk; Joy Das; Takeshi Egawa; Robin M Hobbs; Pier Paolo Pandolfi; Pablo Pereira; Kim E Nichols; Gary A Koretzky; Martha S Jordan; Derek B Sant'Angelo
Development of promyelocytic zinc finger and ThPOK-expressing innate gamma delta T cells is controlled by strength of TCR signaling and Id3.
Journal of immunology (Baltimore, Md. : 1950) 2010;184(3):1268-79.
2009: Bu Yin; Velibor Savic; Marisa M Juntilla; Andrea L Bredemeyer; Katherine S Yang-Iott; Beth A Helmink; Gary A Koretzky; Barry P Sleckman; Craig H Bassing
Histone H2AX stabilizes broken DNA strands to suppress chromosome breaks and translocations during V(D)J recombination.
The Journal of experimental medicine 2009;206(12):2625-39.
2009: Cosima T Baldari; Gary A Koretzky
Lymphocyte signaling in the Tuscan hills.
Immunity 2009;31(5):692-5.
2009: Taku Kambayashi; David F Larosa; Michael A Silverman; Gary A Koretzky
Cooperation of adapter molecules in proximal signaling cascades during allergic inflammation.
Immunological reviews 2009;232(1):99-114.
2009: Laurie E Lenox; Taku Kambayashi; Mariko Okumura; Christopher Prieto; Karsten Sauer; Ralph M Bunte; Martha S Jordan; Gary A Koretzky; Kim E Nichols
Mutation of tyrosine 145 of lymphocyte cytosolic protein 2 protects mice from anaphylaxis and arthritis.
The Journal of allergy and clinical immunology 2009;124(5):1088-98.
2009: Amnon Altman; Gary A Koretzky; Constantine D Tsoukas
Navigating the leukocyte signaling maze guided by Ariadne's thread.
Nature immunology 2009;10(11):1134-6.
2009: R G Baker; C J Hsu; D Lee; Martha S Jordan; Jonathan S Maltzman; D A Hammer; Tobias Baumgart; Gary A Koretzky
The adapter protein SLP-76 mediates "outside-in" integrin signaling and function in T cells.
Molecular and cellular biology 2009;29(20):5578-89.
2009: Gary A Koretzky
The Role of SH2 Domain-containing Leukocyte Phosphoprotein of 76 kDa in the Regulation of Immune Cell Development and Function.
Immune network 2009;9(3):75-83.
2009: Natalie A. Bezman; Rebecca G Baker; Laurie E Lenox; Martha S Jordan; Gary A Koretzky
Cutting edge: rescue of pre-TCR but not mature TCR signaling in mice expressing membrane-targeted SLP-76.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(9):5183-7.
2009: Taku Kambayashi; Eric J Allenspach; John T Chang; Tao Zou; Jonathan E Shoag; Steven L Reiner; Andrew J Caton; Gary A Koretzky
Inducible MHC class II expression by mast cells supports effector and regulatory T cell activation.
Journal of immunology (Baltimore, Md. : 1950) 2009;182(8):4686-95.
2009: Hanan Abramovici; Parmiss Mojtabaie; Robin J Parks; Xiaoping Zhong; Gary A Koretzky; Matthew K Topham; Stephen H Gee
Diacylglycerol kinase zeta regulates actin cytoskeleton reorganization through dissociation of Rac1 from RhoGDI.
Molecular biology of the cell 2009;20(7):2049-59.
2009: Y Jeffrey Chiang; Martha S Jordan; Reiko Horai; Pamela L Schwartzberg; Gary A Koretzky; Richard J Hodes
Cbl enforces an SLP76-dependent signaling pathway for T cell differentiation.
The Journal of biological chemistry 2009;284(7):4429-38.
2009: Jennifer E Smith-Garvin; Gary A Koretzky; Martha S Jordan
T cell activation.
Annual review of immunology 2009;27():591-619.
2008: Selene Nunez-Cruz; W C Janice Yeo; Jennifer Rothman; Priti Ojha; Hamid Bassiri; Marisa Juntilla; Dominique Davidson; André Veillette; Gary A Koretzky; Kim E Nichols
Differential requirement for the SAP-Fyn interaction during NK T cell development and function.
Journal of immunology (Baltimore, Md. : 1950) 2008;181(4):2311-20.
2008: Natalie A. Bezman; Lurong Lian; Charles S Abrams; Lawrence F Brass; Mark L Kahn; Martha S Jordan; Gary A Koretzky
Requirements of SLP76 tyrosines in ITAM and integrin receptor signaling and in platelet function in vivo.
The Journal of experimental medicine 2008;205(8):1775-88.
2008: Jonathan S Maltzman; Gary A Koretzky
CD3varepsilon: PeRuSing for positive selection.
Nature immunology 2008;9(5):457-9.
2008: Marisa M Juntilla; Gary A Koretzky
Critical roles of the PI3K/Akt signaling pathway in T cell development.
Immunology letters 2008;116(2):104-10.
2008: Martha S Jordan; Jennifer E Smith; Jeremy C Burns; Jessica-Elise T Austin; Kim E Nichols; Anna C Aschenbrenner; Gary A Koretzky
Complementation in trans of altered thymocyte development in mice expressing mutant forms of the adaptor molecule SLP76.
Immunity 2008;28(3):359-69.
2008: Taku Kambayashi; Jan D Baranski; Rebecca G Baker; Tao Zou; Eric J Allenspach; Jonathan E Shoag; Peter L Jones; Gary A Koretzky
Indirect involvement of allergen-captured mast cells in antigen presentation.
Blood 2008;111(3):1489-96.
2008: Kimberley Ramsey; Nancy Luckashenak; Gary A Koretzky; James L Clements
Impaired thymic selection in mice expressing altered levels of the SLP-76 adaptor protein.
Journal of leukocyte biology 2008;83(2):419-29.
2007: Martha S Jordan; Jonathan S Maltzman; Stefanie Kliche; Jacob Shabason; Jennifer E Smith; Amrom Obstfeld; Burkhart Schraven; Gary A Koretzky
In vivo disruption of T cell development by expression of a dominant-negative polypeptide designed to abolish the SLP-76/Gads interaction.
European journal of immunology 2007;37(10):2961-72.
2007: Tami L Bach; Qing-Min Chen; Wesley T Kerr; Yanfeng Wang; Lurong Lian; John K Choi; Dianqing Wu; Marcelo G Kazanietz; Gary A Koretzky; Sally Zigmond; Charles S Abrams
Phospholipase cbeta is critical for T cell chemotaxis.
Journal of immunology (Baltimore, Md. : 1950) 2007;179(4):2223-7.
2007: Gary A Koretzky
The legacy of the Philadelphia chromosome.
The Journal of clinical investigation 2007;117(8):2030-2.
2007: Cosima T Baldari; Gary A Koretzky
Antigen receptor signaling: the Tuscan connection.
Nature immunology 2007;8(8):787-90.
2007: Natalie A. Bezman; Gary A Koretzky
Compartmentalization of ITAM and integrin signaling by adapter molecules.
Immunological reviews 2007;218():9-28.
2007: Marisa M Juntilla; Jessica A Wofford; Morris J Birnbaum; Jeffrey C Rathmell; Gary A Koretzky
Akt1 and Akt2 are required for alphabeta thymocyte survival and differentiation.
Proceedings of the National Academy of Sciences of the United States of America 2007;104(29):12105-10.
2007: Gaël Ménasché; Stefanie Kliche; Emily J H Chen; Theresia E B Stradal; Burkhart Schraven; Gary A Koretzky
RIAM links the ADAP/SKAP-55 signaling module to Rap1, facilitating T-cell-receptor-mediated integrin activation.
Molecular and cellular biology 2007;27(11):4070-81.
2007: Regina A Clemens; Laurie E Lenox; Taku Kambayashi; Natalie A. Bezman; Jonathan S Maltzman; Kim E Nichols; Gary A Koretzky
Loss of SLP-76 expression within myeloid cells confers resistance to neutrophil-mediated tissue damage while maintaining effective bacterial killing.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(7):4606-14.
2007: Taku Kambayashi; Gary A Koretzky
Proximal signaling events in Fc epsilon RI-mediated mast cell activation.
The Journal of allergy and clinical immunology 2007;119(3):544-52; quiz 553-4.
2007: Bruce Seet; Donna M Berry; Jonathan S Maltzman; Jacob Shabason; Monica Raina; Gary A Koretzky; C Jane McGlade; Tony Pawson
Efficient T-cell receptor signaling requires a high-affinity interaction between the Gads C-SH3 domain and the SLP-76 RxxK motif.
The EMBO journal 2007;26(3):678-89.
2007: Tami L Bach; Wesley T Kerr; Yanfeng Wang; Eve Marie Bauman; Purnima Kine; Eileen L Whiteman; Renell S Morgan; Edward K Williamson; E Michael Ostap; Janis Burkhardt; Gary A Koretzky; Morris J Birnbaum; Charles S Abrams
PI3K regulates pleckstrin-2 in T-cell cytoskeletal reorganization.
Blood 2007;109(3):1147-55.
2007: Ana Kasirer-Friede; Barry Moran; Jennifer Nagrampa-Orje; Ken Swanson; Zaverio M Ruggeri; Burkhart Schraven; Benjamin G Neel; Gary A Koretzky; Sanford J Shattil
ADAP is required for normal alphaIIbbeta3 activation by VWF/GP Ib-IX-V and other agonists.
Blood 2007;109(3):1018-25.
2007: Xiaoping Zhong; B A Olenchock; Gary A Koretzky
The role of diacylglycerol kinases in T cell anergy.
Ernst Schering Foundation symposium proceedings 2007;(3):139-49.
2007: Jun-ichiro Suzuki; Sho Yamasaki; Jennifer Nan-Wah Wu; Gary A Koretzky; Takashi Saito
The actin cloud induced by LFA-1-mediated outside-in signals lowers the threshold for T-cell activation.
Blood 2007;109(1):168-75.
2006: Mark L Kahn; Gary A Koretzky
Integrins and ITAMs: more than just good neighbors.
Nature immunology 2006;7(12):1286-8.
2006: Benjamin A Olenchock; Rishu Guo; Jeffery H Carpenter; Martha Jordan; Matthew K Topham; Gary A Koretzky; Xiaoping Zhong
Disruption of diacylglycerol metabolism impairs the induction of T cell anergy.
Nature immunology 2006;7(11):1174-81.
2006: Stephen C Bunnell; ANDREW SINGER; David I Hong; Berri H Jacque; Martha S Jordan; Maria-Cristina Seminario; Valarie A Barr; Gary A Koretzky; Lawrence E Samelson
Persistence of cooperatively stabilized signaling clusters drives T-cell activation.
Molecular and cellular biology 2006;26(19):7155-66.
2006: Stefanie Kliche; Dennis Breitling; Mauro Togni; Rico Pusch; Katja Heuer; Xiaoqian Wang; Christian Freund; Ana Kasirer-Friede; Gael Menasche; Gary A Koretzky; Burkhart Schraven
The ADAP/SKAP55 signaling module regulates T-cell receptor-mediated integrin activation through plasma membrane targeting of Rap1.
Molecular and cellular biology 2006;26(19):7130-44.
2006: Eric Sebzda; Christopher Hibbard; Shawn Sweeney; Farhad Abtahian; Natalie A. Bezman; Gina Clemens; Jonathan S Maltzman; Lan Cheng; Feiyan Liu; Martin Turner; Victor L J Tybulewicz; Gary A Koretzky; Mark L Kahn
Syk and Slp-76 mutant mice reveal a cell-autonomous hematopoietic cell contribution to vascular development.
Developmental cell 2006;11(3):349-61.
2006: Farhad Abtahian; Natalie A. Bezman; Regina A Clemens; Eric Sebzda; Lan Cheng; Sanford J Shattil; Mark L Kahn; Gary A Koretzky
Evidence for the requirement of ITAM domains but not SLP-76/Gads interaction for integrin signaling in hematopoietic cells.
Molecular and cellular biology 2006;26(18):6936-49.
2006: Benjamin A Olenchock; Rishu Guo; Michael A Silverman; Jennifer Nan-Wah Wu; Jeffery H Carpenter; Gary A Koretzky; Xiaoping Zhong
Impaired degranulation but enhanced cytokine production after Fc epsilonRI stimulation of diacylglycerol kinase zeta-deficient mast cells.
The Journal of experimental medicine 2006;203(6):1471-80.
2006: Jennifer Nan-Wah Wu; Shereen Gheith; Natalie A. Bezman; Qing-Hua Liu; Lindsey V Fostel; Andrew M Swanson; Bruce D Freedman; Gary A Koretzky; Erik J Peterson
Adhesion- and degranulation-promoting adapter protein is required for efficient thymocyte development and selection.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(11):6681-9.
2006: Michael A Silverman; Jonathan Shoag; Jennifer Nan-Wah Wu; Gary A Koretzky
Disruption of SLP-76 interaction with Gads inhibits dynamic clustering of SLP-76 and FcepsilonRI signaling in mast cells.
Molecular and cellular biology 2006;26(5):1826-38.
2006: Martha S Jordan; Jeffrey Sadler; Jessica E Austin; Lisa D Finkelstein; ANDREW SINGER; Pamela L Schwartzberg; Gary A Koretzky
Functional hierarchy of the N-terminal tyrosines of SLP-76.
Journal of immunology (Baltimore, Md. : 1950) 2006;176(4):2430-8.
2006: Gary A Koretzky; Farhad Abtahian; Michael A Silverman
SLP76 and SLP65: complex regulation of signalling in lymphocytes and beyond.
Nature reviews. Immunology 2006;6(1):67-78.
2005: Jonathan S Maltzman; Lisa Kovoor; James L Clements; Gary A Koretzky
Conditional deletion reveals a cell-autonomous requirement of SLP-76 for thymocyte selection.
The Journal of experimental medicine 2005;202(7):893-900.
2005: Kim E Nichols; Jamie Hom; Shun-You Gong; Arupa Ganguly; Cindy S Ma; Jennifer L Cannons; Stuart G Tangye; Pamela L Schwartzberg; Gary A Koretzky; Paul L Stein
Regulation of NKT cell development by SAP, the protein defective in XLP.
Nature medicine 2005;11(3):340-5.
2005: Cosima T Baldari; Gary A Koretzky; John L Telford; Oreste Acuto
Antigen receptor signaling: the Tuscan chronicles.
Nature immunology 2005;6(1):3-5.
2004: Regina A Clemens; Sally A Newbrough; Elaine Y Chung; Shereen Gheith; ANDREW SINGER; Gary A Koretzky; Erik J Peterson
PRAM-1 is required for optimal integrin-dependent neutrophil function.
Molecular and cellular biology 2004;24(24):10923-32.
2004: Jennifer Nan-Wah Wu; Gary A Koretzky
The SLP-76 family of adapter proteins.
Seminars in immunology 2004;16(6):379-93.
2004: Jennifer L Cannons; Li J Yu; Brenna Hill; Lilia Mijares; Derek Dombroski; Kim E Nichols; Anthony Antonellis; Gary A Koretzky; Kevin Gardner; Pamela L Schwartzberg
SAP regulates T(H)2 differentiation and PKC-theta-mediated activation of NF-kappaB1.
Immunity 2004;21(5):693-706.
2004: David Artis; Alejandro V Villarino; Michael Silverman; Weimian He; Elisabeth M Thornton; Sharon Mu; Shamin Summer; Todd M Covey; Elaine Huang; Hiroki Yoshida; Gary A Koretzky; Michael H Goldschmidt; Gary D Wu; Frederic J de Sauvage; Hugh Miller; Christiaan J M Saris; Phillip Scott; Christopher A Hunter
The IL-27 receptor (WSX-1) is an inhibitor of innate and adaptive elements of type 2 immunity.
Journal of immunology (Baltimore, Md. : 1950) 2004;173(9):5626-34.
2004: Y Jeffrey Chiang; Connie L Sommers; Martha S Jordan; Hua Gu; Lawrence E Samelson; Gary A Koretzky; Richard J Hodes
Inactivation of c-Cbl reverses neonatal lethality and T cell developmental arrest of SLP-76-deficient mice.
The Journal of experimental medicine 2004;200(1):25-34.
2004: Jennifer Nan-Wah Wu; Martha S Jordan; Michael A Silverman; Erik J Peterson; Gary A Koretzky
Differential requirement for adapter proteins Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa and adhesion- and degranulation-promoting adapter protein in FcepsilonRI signaling and mast cell function.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):6768-74.
2004: ANDREW SINGER; Stephen C Bunnell; Amrom Obstfeld; Martha S Jordan; Jennifer Nan-Wah Wu; Peggy S Myung; Lawrence E Samelson; Gary A Koretzky
Roles of the proline-rich domain in SLP-76 subcellular localization and T cell function.
The Journal of biological chemistry 2004;279(15):15481-90.
2004: Kim E Nichols; Kathleen Haines; Peggy S Myung; Sally A Newbrough; Erin Myers; Hassan Jumaa; Devon Shedlock; Hao Shen; Gary A Koretzky
Macrophage activation and Fcgamma receptor-mediated signaling do not require expression of the SLP-76 and SLP-65 adaptors.
Journal of leukocyte biology 2004;75(3):541-52.
2003: Xiaoping Zhong; Jonathan S Maltzman; Ehmonie A Hainey; Gary A Koretzky
Transcriptional regulation of Src homology 2 domain-containing leukocyte phosphoprotein of 76 kDa: dissection of key promoter elements.
Journal of immunology (Baltimore, Md. : 1950) 2003;171(12):6621-9.
2003: Sally A Newbrough; Attila Mócsai; Regina A Clemens; Jennifer Nan-Wah Wu; Michael A Silverman; ANDREW SINGER; Clifford A Lowell; Gary A Koretzky
SLP-76 regulates Fcgamma receptor and integrin signaling in neutrophils.
Immunity 2003;19(5):761-9.
2003: Xiaoping Zhong; Ehmonie A Hainey; Benjamin A Olenchock; Martha S Jordan; Jonathan S Maltzman; Kim E Nichols; Hao Shen; Gary A Koretzky
Enhanced T cell responses due to diacylglycerol kinase zeta deficiency.
Nature immunology 2003;4(9):882-90.
2003: Jonathan S Maltzman; Gary A Koretzky
Azathioprine: old drug, new actions.
The Journal of clinical investigation 2003;111(8):1122-4.
2003: Gary A Koretzky
T cell activation I: proximal events.
Immunological reviews 2003;191():5-6.
2003: Martha S Jordan; ANDREW SINGER; Gary A Koretzky
Adaptors as central mediators of signal transduction in immune cells.
Nature immunology 2003;4(2):110-6.
2003: Farhad Abtahian; Anastasia Guerriero; Eric Sebzda; Min Min Lu; Rong Zhou; Attila Mócsai; Erin E Myers; Bin Huang; David G Jackson; Victor A Ferrari; Victor L J Tybulewicz; Clifford A Lowell; John J Lepore; Gary A Koretzky; Mark L Kahn
Regulation of blood and lymphatic vascular separation by signaling proteins SLP-76 and Syk.
Science (New York, N.Y.) 2003;299(5604):247-51.
2003: Gary A Koretzky; Farhad Abtahian; Geo S Derimanov; Sally A Dmowski; Anastasia Guerriero; Martha S Jordan; Jonathan S Maltzman; Benjamin A Olenchock; ANDREW SINGER; Jennifer Nan-Wah Wu; Xiaoping Zhong
Regulation of hematopoietic cell development and activation by adapter proteins.
Immunologic research 2003;27(2-3):357-66.
2002: Birgit Kovacs; Marcela V Maus; James L Riley; Geo S Derimanov; Gary A Koretzky; Carl H June; Terri H Finkel
Human CD8+ T cells do not require the polarization of lipid rafts for activation and proliferation.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(23):15006-11.
2002: Lorie Leo; Jorge Di Paola; Barbi A Judd; Gary A Koretzky; Steven R Lentz
Role of the adapter protein SLP-76 in GPVI-dependent platelet procoagulant responses to collagen.
Blood 2002;100(8):2839-44.
2002: Xiaoping Zhong; Ehmonie A Hainey; Benjamin A Olenchock; Haoran Zhao; Matthew K Topham; Gary A Koretzky
Regulation of T cell receptor-induced activation of the Ras-ERK pathway by diacylglycerol kinase zeta.
The Journal of biological chemistry 2002;277(34):31089-98.
2002: ANDREW SINGER; Gary A Koretzky
Control of T cell function by positive and negative regulators.
Science (New York, N.Y.) 2002;296(5573):1639-40.
2002: Barbi A Judd; Peggy S Myung; Achim Obergfell; Erin E Myers; Alec M Cheng; Steve P Watson; Warren S Pear; David Allman; Sanford J Shattil; Gary A Koretzky
Differential requirement for LAT and SLP-76 in GPVI versus T cell receptor signaling.
The Journal of experimental medicine 2002;195(6):705-17.
2002: Gary A Koretzky
Stimulation and inhibition of immune responses: an intricate balancing act.
The Journal of clinical investigation 2002;109(1):7-8.
2001: Peggy S Myung; Geo S Derimanov; Martha S Jordan; Jennifer A Punt; Qing-Hua Liu; Barbi A Judd; E E Meyers; Curt D Sigmund; Bruce D Freedman; Gary A Koretzky
Differential requirement for SLP-76 domains in T cell development and function.
Immunity 2001;15(6):1011-26.
2001: David Tulasne; B A Judd; M Johansen; Naoki Asazuma; Denise Best; E J Brown; M Kahn; Gary A Koretzky; Steve P Watson
C-terminal peptide of thrombospondin-1 induces platelet aggregation through the Fc receptor gamma-chain-associated signaling pathway and by agglutination.
Blood 2001;98(12):3346-52.
2001: Gary A Koretzky; Peggy S Myung
Positive and negative regulation of T-cell activation by adaptor proteins.
Nature reviews. Immunology 2001;1(2):95-107.
2001: Gary A Koretzky
The future of the ASCI (American Society for Clinical Investigation) : a lesson from 2000 presidential election.
The Journal of clinical investigation 2001;108(7):s3-s7.
2001: Barbi A Judd; Gary A Koretzky
The role of the adapter molecule SLP-76 in platelet function.
Oncogene 2001;20(44):6291-9.
2001: Erik J Peterson; M L Woods; Sally A Dmowski; Geo S Derimanov; Martha S Jordan; Jennifer Nan-Wah Wu; Peggy S Myung; Qing-Hua Liu; J T Pribila; Bruce D Freedman; Yoji Shimizu; Gary A Koretzky
Coupling of the TCR to integrin activation by Slap-130/Fyb.
Science (New York, N.Y.) 2001;293(5538):2263-5.
2001: David Allman; Fredrick G Karnell; Jennifer A Punt; Sonia Bakkour; Lingfei Xu; Peggy S Myung; Gary A Koretzky; JC Pui; Jon C Aster; Warren S Pear
Separation of Notch1 promoted lineage commitment and expansion/transformation in developing T cells.
The Journal of experimental medicine 2001;194(1):99-106.
2001: Christel Moog-Lutz; E J Peterson; Pierre G Lutz; Steven L Eliason; Florence Cavé-Riant; ANDREW SINGER; Yolande Di Gioia; Sally A Dmowski; J Kamens; Yvon E Cayre; Gary A Koretzky
PRAM-1 is a novel adaptor protein regulated by retinoic acid (RA) and promyelocytic leukemia (PML)-RA receptor alpha in acute promyelocytic leukemia cells.
The Journal of biological chemistry 2001;276(25):22375-81.
2001: David J Izon; Jennifer A Punt; Lingfei Xu; Fredrick G Karnell; David Allman; Peggy S Myung; NJ Boerth; JC Pui; Gary A Koretzky; Warren S Pear
Notch1 regulates maturation of CD4+ and CD8+ thymocytes by modulating TCR signal strength.
Immunity 2001;14(3):253-64.
2001: Achim Obergfell; Barbi A Judd; Miguel A Del Pozo; Martin A Schwartz; Gary A Koretzky; Sanford J Shattil
The molecular adapter SLP-76 relays signals from platelet integrin alphaIIbbeta3 to the actin cytoskeleton.
The Journal of biological chemistry 2001;276(8):5916-23.
2000: Barbi A Judd; Peggy S Myung; L Leng; Achim Obergfell; Warren S Pear; Sanford J Shattil; Gary A Koretzky
Hematopoietic reconstitution of SLP-76 corrects hemostasis and platelet signaling through alpha IIb beta 3 and collagen receptors.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(22):12056-61.
2000: NJ Boerth; J J Sadler; Daniel E Bauer; James L Clements; Shereen Gheith; Gary A Koretzky
Recruitment of SLP-76 to the membrane and glycolipid-enriched membrane microdomains replaces the requirement for linker for activation of T cells in T cell receptor signaling.
The Journal of experimental medicine 2000;192(7):1047-58.
2000: Peggy S Myung; James L Clements; DW White; Zulfiqar A Malik; John S Cowdery; L H Allen; John T Harty; David J Kusner; Gary A Koretzky
In vitro and in vivo macrophage function can occur independently of SLP-76.
International immunology 2000;12(6):887-97.
2000: Peggy S Myung; N J Boerthe; Gary A Koretzky
Adapter proteins in lymphocyte antigen-receptor signaling.
Current opinion in immunology 2000;12(3):256-66.
2000: LA Norian; KM Latinis; Steven L Eliason; K Lyson; C Yang; Timothy L Ratliff; Gary A Koretzky
The regulation of CD95 (Fas) ligand expression in primary T cells: induction of promoter activation in CD95LP-Luc transgenic mice.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4471-80.
2000: NJ Boerth; Barbi A Judd; Gary A Koretzky
Functional association between SLAP-130 and SLP-76 in Jurkat T cells.
The Journal of biological chemistry 2000;275(7):5143-52.
2000: LA Norian; Gary A Koretzky
Intracellular adapter molecules.
Seminars in immunology 2000;12(1):43-54.
2000: A J Hunter; N Ottoson; NJ Boerth; Gary A Koretzky; Y Shimizu
Cutting edge: a novel function for the SLAP-130/FYB adapter protein in beta 1 integrin signaling and T lymphocyte migration.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(3):1143-7.
2000: Barbi A Judd; Gary A Koretzky
Antigen specific T lymphocyte activation.
Reviews in immunogenetics 2000;2(2):164-74.
1999: JM Pasquet; B Gross; LS Quek; Naoki Asazuma; W Zhang; Connie L Sommers; Edina Schweighoffer; Victor L J Tybulewicz; B Judd; J R Lee; Gary A Koretzky; Paul E Love; Lawrence E Samelson; Steve P Watson
LAT is required for tyrosine phosphorylation of phospholipase cgamma2 and platelet activation by the collagen receptor GPVI.
Molecular and cellular biology 1999;19(12):8326-34.
1999: Erik J Peterson; James L Clements; Zuhair K Ballas; Gary A Koretzky
NK cytokine secretion and cytotoxicity occur independently of the SLP-76 adaptor protein.
European journal of immunology 1999;29(7):2223-32.
1999: N Fang; Gary A Koretzky
SLP-76 and Vav function in separate, but overlapping pathways to augment interleukin-2 promoter activity.
The Journal of biological chemistry 1999;274(23):16206-12.
1999: John S Cowdery; NJ Boerth; LA Norian; Peggy S Myung; Gary A Koretzky
Differential regulation of the IL-12 p40 promoter and of p40 secretion by CpG DNA and lipopolysaccharide.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6770-5.
1999: NJ Boerth; Gary A Koretzky
Adapter molecules in T cell receptor signaling.
Inflammatory bowel diseases 1999;5(2):107-18.
1999: James L Clements; Gary A Koretzky
Recent developments in lymphocyte activation: linking kinases to downstream signaling events.
The Journal of clinical investigation 1999;103(7):925-9.
1999: Rama K Mallampalli; Erik J Peterson; A Brent Carter; Ronald G Salome; Satya N Mathur; Gary A Koretzky
TNF-alpha increases ceramide without inducing apoptosis in alveolar type II epithelial cells.
The American journal of physiology 1999;276(3 Pt 1):L481-90.
1999: BS Gross; J R Lee; J L Clements; Martin Turner; Victor L J Tybulewicz; P R Findell; Gary A Koretzky; Steve P Watson
Tyrosine phosphorylation of SLP-76 is downstream of Syk following stimulation of the collagen receptor in platelets.
The Journal of biological chemistry 1999;274(9):5963-71.
1999: James L Clements; NJ Boerth; J R Lee; Gary A Koretzky
Integration of T cell receptor-dependent signaling pathways by adapter proteins.
Annual review of immunology 1999;17():89-108.
1999: Erik J Peterson; Gary A Koretzky
Signal transduction in T lymphocytes.
Clinical and experimental rheumatology 1999;17(1):107-14.
1999: James L Clements; J R Lee; B Gross; Baoli Yang; John D Olson; Alexander Sandra; Steve P Watson; Steven R Lentz; Gary A Koretzky
Fetal hemorrhage and platelet dysfunction in SLP-76-deficient mice.
The Journal of clinical investigation 1999;103(1):19-25.
1998: J R Lee; Gary A Koretzky
Production of reactive oxygen intermediates following CD40 ligation correlates with c-Jun N-terminal kinase activation and IL-6 secretion in murine B lymphocytes.
European journal of immunology 1998;28(12):4188-97.
1998: James L Clements; Susan E Ross-Barta; Lorraine T Tygrett; Thomas J Waldschmidt; Gary A Koretzky
SLP-76 expression is restricted to hemopoietic cells of monocyte, granulocyte, and T lymphocyte lineage and is regulated during T cell maturation and activation.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(8):3880-9.
1998: Anne Marie-Cardine; LR Hendricks-Taylor; NJ Boerth; H Zhao; Burkhart Schraven; Gary A Koretzky
Molecular interaction between the Fyn-associated protein SKAP55 and the SLP-76-associated phosphoprotein SLAP-130.
The Journal of biological chemistry 1998;273(40):25789-95.
1998: M Faris; KM Latinis; SJ Kempiak; Gary A Koretzky; Andre E Nel
Stress-induced Fas ligand expression in T cells is mediated through a MEK kinase 1-regulated response element in the Fas ligand promoter.
Molecular and cellular biology 1998;18(9):5414-24.
1998: J R Lee; Gary A Koretzky
Extracellular signal-regulated kinase-2, but not c-Jun NH2-terminal kinase, activation correlates with surface IgM-mediated apoptosis in the WEHI 231 B cell line.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(4):1637-44.
1998: LA Norian; KM Latinis; Gary A Koretzky
A newly identified response element in the CD95 ligand promoter contributes to optimal inducibility in activated T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(3):1078-82.
1998: James L Clements; Baoli Yang; Susan E Ross-Barta; Steven L Eliason; Ronald Hrstka; Roger A Williamson; Gary A Koretzky
Requirement for the leukocyte-specific adapter protein SLP-76 for normal T cell development.
Science (New York, N.Y.) 1998;281(5375):416-9.
1998: Erik J Peterson; James L Clements; N Fang; Gary A Koretzky
Adaptor proteins in lymphocyte antigen-receptor signaling.
Current opinion in immunology 1998;10(3):337-44.
1998: Erik J Peterson; KM Latinis; Gary A Koretzky
Molecular characterization of a CD95 signaling mutant.
Arthritis and rheumatism 1998;41(6):1047-53.
1998: H Zhao; S Okada; Jeffrey Pessin; Gary A Koretzky
Insulin receptor-mediated dissociation of Grb2 from Sos involves phosphorylation of Sos by kinase(s) other than extracellular signal-regulated kinase.
The Journal of biological chemistry 1998;273(20):12061-7.
1998: M Faris; N Kokot; KM Latinis; S Kasibhatla; D R Green; Gary A Koretzky; Andre E Nel
The c-Jun N-terminal kinase cascade plays a role in stress-induced apoptosis in Jurkat cells by up-regulating Fas ligand expression.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(1):134-44.
1997: KM Latinis; LA Norian; Steven L Eliason; Gary A Koretzky
Two NFAT transcription factor binding sites participate in the regulation of CD95 (Fas) ligand expression in activated human T cells.
The Journal of biological chemistry 1997;272(50):31427-34.
1997: H Zhao; Y Y Li; Raymond V Fucini; SE Ross; Jeffrey Pessin; Gary A Koretzky
T cell receptor-induced phosphorylation of Sos requires activity of CD45, Lck, and protein kinase C, but not ERK.
The Journal of biological chemistry 1997;272(34):21625-34.
1997: MA Musci; David G Motto; SE Ross; N Fang; Gary A Koretzky
Three domains of SLP-76 are required for its optimal function in a T cell line.
Journal of immunology (Baltimore, Md. : 1950) 1997;159(4):1639-47.
1997: H Zhao; Gary A Koretzky
Regulation of signal transduction through the T cell antigen receptor.
The Journal of laboratory and clinical medicine 1997;130(2):126-31.
1997: Gary A Koretzky
The role of Grb2-associated proteins in T-cell activation.
Immunology today 1997;18(8):401-6.
1997: Burkhart Schraven; Anne Marie-Cardine; Gary A Koretzky
Molecular analysis of the fyn-complex: cloning of SKAP55 and SLAP-130, two novel adaptor proteins which associate with fyn and may participate in the regulation of T cell receptor-mediated signaling.
Immunology letters 1997;57(1-3):165-9.
1997: MA Musci; KM Latinis; Gary A Koretzky
Signaling events in T lymphocytes leading to cellular activation or programmed cell death.
Clinical immunology and immunopathology 1997;83(3):205-22.
1997: KM Latinis; L L Carr; Erik J Peterson; LA Norian; Steven L Eliason; Gary A Koretzky
Regulation of CD95 (Fas) ligand expression by TCR-mediated signaling events.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4602-11.
1997: MA Musci; LR Hendricks-Taylor; David G Motto; M Paskind; J Kamens; C W Turck; Gary A Koretzky
Molecular cloning of SLAP-130, an SLP-76-associated substrate of the T cell antigen receptor-stimulated protein tyrosine kinases.
The Journal of biological chemistry 1997;272(18):11674-7.
1997: Frederick D Goldman; J Crabtree; Clay Hollenback; Gary A Koretzky
Sequestration of p56(lck) by gp120, a model for TCR desensitization.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(5):2017-24.
1997: MA Musci; S L Beaves; SE Ross; T Yi; Gary A Koretzky
Surface expression of hemopoietic cell phosphatase fails to complement CD45 deficiency and inhibits TCR-mediated signal transduction in a Jurkat T cell clone.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(4):1565-71.
1997: LR Hendricks-Taylor; David G Motto; J Zhang; R P Siraganian; Gary A Koretzky
SLP-76 is a substrate of the high affinity IgE receptor-stimulated protein tyrosine kinases in rat basophilic leukemia cells.
The Journal of biological chemistry 1997;272(2):1363-7.
1996: Frederick D Goldman; Raymond J Hohl; J Crabtree; K Lewis-Tibesar; Gary A Koretzky
Lovastatin inhibits T-cell antigen receptor signaling independent of its effects on ras.
Blood 1996;88(12):4611-9.
1996: N Fang; David G Motto; S E Ross; Gary A Koretzky
Tyrosines 113, 128, and 145 of SLP-76 are required for optimal augmentation of NFAT promoter activity.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(9):3769-73.
1996: H Onodera; David G Motto; Gary A Koretzky; David M Rothstein
Differential regulation of activation-induced tyrosine phosphorylation and recruitment of SLP-76 to Vav by distinct isoforms of the CD45 protein-tyrosine phosphatase.
The Journal of biological chemistry 1996;271(36):22225-30.
1996: Y Y Li; M Baccam; S B Waters; Jeffrey Pessin; Gail A Bishop; Gary A Koretzky
CD40 ligation results in protein kinase C-independent activation of ERK and JNK in resting murine splenic B cells.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(4):1440-7.
1996: S L Sunden; L L Carr; James L Clements; David G Motto; Gary A Koretzky
Polymorphism in and localization of the gene LCP2 (SLP-76) to chromosome 5q33.1-qter.
Genomics 1996;35(1):269-70.
1996: J Wu; David G Motto; Gary A Koretzky; Arthur Weiss
Vav and SLP-76 interact and functionally cooperate in IL-2 gene activation.
Immunity 1996;4(6):593-602.
1996: David G Motto; MA Musci; S E Ross; Gary A Koretzky
Tyrosine phosphorylation of Grb2-associated proteins correlates with phospholipase C gamma 1 activation in T cells.
Molecular and cellular biology 1996;16(6):2823-9.
1996: KH Holt; S B Waters; S Okada; K Yamauchi; S J Decker; Alan Saltiel; David G Motto; Gary A Koretzky; Jeffrey Pessin
Epidermal growth factor receptor targeting prevents uncoupling of the Grb2-SOS complex.
The Journal of biological chemistry 1996;271(14):8300-6.
1996: David G Motto; S E Ross; J Wu; L R Hendricks-Taylor; Gary A Koretzky
Implication of the GRB2-associated phosphoprotein SLP-76 in T cell receptor-mediated interleukin 2 production.
The Journal of experimental medicine 1996;183(4):1937-43.
1996: KM Latinis; Gary A Koretzky
Fas ligation induces apoptosis and Jun kinase activation independently of CD45 and Lck in human T cells.
Blood 1996;87(3):871-5.
1995: Eddy Bruyns; L R Hendricks-Taylor; Stefan C Meuer; Gary A Koretzky; Burkhart Schraven
Identification of the sites of interaction between lymphocyte phosphatase-associated phosphoprotein (LPAP) and CD45.
The Journal of biological chemistry 1995;270(52):31372-6.
1995: S B Waters; KH Holt; S E Ross; Li-Jyun Syu; K L Guan; Alan Saltiel; Gary A Koretzky; Jeffrey Pessin
Desensitization of Ras activation by a feedback disassociation of the SOS-Grb2 complex.
The Journal of biological chemistry 1995;270(36):20883-6.
1995: Paul B McCray; K Armstrong; Joseph Zabner; D W Miller; Gary A Koretzky; L Couture; Josée Robillard; AE Smith; Michael J Welsh
Adenoviral-mediated gene transfer to fetal pulmonary epithelia in vitro and in vivo.
The Journal of clinical investigation 1995;95(6):2620-32.
1995: Arthur M Krieg; Ae-Kyung Yi; S Matson; Thomas J Waldschmidt; G A Bishop; R Teasdale; Gary A Koretzky; D M Klinman
CpG motifs in bacterial DNA trigger direct B-cell activation.
Nature 1995;374(6522):546-9.
1995: J K Jackman; David G Motto; Q Sun; M Tanemoto; C W Turck; G A Peltz; Gary A Koretzky; P R Findell
Molecular cloning of SLP-76, a 76-kDa tyrosine phosphoprotein associated with Grb2 in T cells.
The Journal of biological chemistry 1995;270(13):7029-32.
1994: Burkhart Schraven; D Schoenhaut; Eddy Bruyns; Gary A Koretzky; C Eckerskorn; Reinhard Wallich; Henning Kirchgessner; P Sakorafas; B Labkovsky; S Ratnofsky
LPAP, a novel 32-kDa phosphoprotein that interacts with CD45 in human lymphocytes.
The Journal of biological chemistry 1994;269(46):29102-11.
1994: David G Motto; MA Musci; Gary A Koretzky
Surface expression of a heterologous phosphatase complements CD45 deficiency in a T cell clone.
The Journal of experimental medicine 1994;180(4):1359-66.
1994: David G Motto; S E Ross; J K Jackman; Q Sun; Ann Louise Olson; P R Findell; Gary A Koretzky
In vivo association of Grb2 with pp116, a substrate of the T cell antigen receptor-activated protein tyrosine kinase.
The Journal of biological chemistry 1994;269(34):21608-13.
1994: J A Donovan; Frederick D Goldman; Gary A Koretzky
Restoration of CD2-mediated signaling by a chimeric membrane protein including the cytoplasmic sequence of CD45.
Human immunology 1994;40(2):123-30.
1994: S E Ross; Burkhart Schraven; Frederick D Goldman; J Crabtree; Gary A Koretzky
The association between CD45 and lck does not require CD4 or CD8 and is independent of T cell receptor stimulation.
Biochemical and biophysical research communications 1994;198(1):88-96.
1993: J A Donovan; Gary A Koretzky
CD45 and the immune response.
Journal of the American Society of Nephrology : JASN 1993;4(4):976-85.
1993: Gary A Koretzky; M Kohmetscher; S Ross
CD45-associated kinase activity requires lck but not T cell receptor expression in the Jurkat T cell line.
The Journal of biological chemistry 1993;268(12):8958-64.
1993: Robin R. Hovis; J A Donovan; MA Musci; David G Motto; Frederick D Goldman; S E Ross; Gary A Koretzky
Rescue of signaling by a chimeric protein containing the cytoplasmic domain of CD45.
Science (New York, N.Y.) 1993;260(5107):544-6.
1993: Gail A Bishop; L M Ramirez; Gary A Koretzky
Growth inhibition of a B cell clone mediated by ligation of IL-4 receptors or membrane IgM.
Journal of immunology (Baltimore, Md. : 1950) 1993;150(7):2565-74.
1993: Gary A Koretzky
Role of the CD45 tyrosine phosphatase in signal transduction in the immune system.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1993;7(5):420-6.
1992: Gary A Koretzky; M A Kohmetscher; T Kadleck; A Weiss
Restoration of T cell receptor-mediated signal transduction by transfection of CD45 cDNA into a CD45-deficient variant of the Jurkat T cell line.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(4):1138-42.
1991: Arthur Weiss; B A Irving; L K Tan; Gary A Koretzky
Signal transduction by the T cell antigen receptor.
Seminars in immunology 1991;3(5):313-24.
1991: Arthur Weiss; Gary A Koretzky; R C Schatzman; T Kadlecek
Functional activation of the T-cell antigen receptor induces tyrosine phosphorylation of phospholipase C-gamma 1.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(13):5484-8.
1991: Gary A Koretzky; J Picus; T Schultz; Arthur Weiss
Tyrosine phosphatase CD45 is required for T-cell antigen receptor and CD2-mediated activation of a protein tyrosine kinase and interleukin 2 production.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(6):2037-41.
1991: Arthur Weiss; D Desai; M Graber; J Picus; Gary A Koretzky
The regulation of T-cell antigen receptor signal transduction function.
Transplantation proceedings 1991;23(1 Pt 1):32-3.
1990: Gary A Koretzky; J Picus; M L Thomas; Arthur Weiss
Tyrosine phosphatase CD45 is essential for coupling T-cell antigen receptor to the phosphatidyl inositol pathway.
Nature 1990;346(6279):66-8.
1989: Gary A Koretzky; M Wahi; M E Newton; Arthur Weiss
Heterogeneity of protein kinase C isoenzyme gene expression in human T cell lines. Protein kinase C-beta is not required for several T cell functions.
Journal of immunology (Baltimore, Md. : 1950) 1989;143(5):1692-5.
1987: Linda K Bockenstedt; Mark A Goldsmith; Gary A Koretzky; Arthur Weiss
The activation of T lymphocytes.
Rheumatic diseases clinics of North America 1987;13(3):411-30.