FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Robert Korneluk

Research Profile

Chemicals & Drugs

Disorders

Myotonic Dystrophy

Anatomy

Chromosomes, Human, Pair 19

Concepts & Ideas

Living Beings

Mouse

Procedures

Physiology

Polymorphism, Restriction Fragment Length

Genes & Molecular Sequences

Co-author Network

Publications

TOP 3
Emeka K Enwere; Janelle Holbrook; Louise Boudreault; Nathalie Earl; Eric LaCasse; Jean-Marc Renaud; Kristen Timusk; Robert G Korneluk
Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice.
Shawn T Beug; Herman H Cheung; Eric C LaCasse; Robert G Korneluk
Modulation of immune signalling by inhibitors of apoptosis.
Emeka K Enwere; Janelle Holbrook; Methvin Isaac; Eric C LaCasse; Rim Lejmi-Mrad; Baktharaman Sivaraj; Kristen Timusk; David Uehling; Jennifer Vineham; Rima Al-awar; Robert G Korneluk
TWEAK and cIAP1 regulate myoblast fusion through the noncanonical NF-κB signaling pathway.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Robert Korneluk (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Emeka K Enwere; Janelle Holbrook; Louise Boudreault; Nathalie Earl; Eric LaCasse; Jean-Marc Renaud; Kristen Timusk; Robert G Korneluk
Loss of cIAP1 attenuates soleus muscle pathology and improves diaphragm function in mdx mice.
Human molecular genetics 2013;22(5):867-78.
2012: Shawn T Beug; Herman H Cheung; Eric C LaCasse; Robert G Korneluk
Modulation of immune signalling by inhibitors of apoptosis.
Trends in immunology 2012;33(11):535-45.
2012: Emeka K Enwere; Janelle Holbrook; Methvin Isaac; Eric C LaCasse; Rim Lejmi-Mrad; Baktharaman Sivaraj; Kristen Timusk; David Uehling; Jennifer Vineham; Rima Al-awar; Robert G Korneluk
TWEAK and cIAP1 regulate myoblast fusion through the noncanonical NF-κB signaling pathway.
Science signaling 2012;5(246):ra75.
2011: Herman H Cheung; M St Jean; S T Beug; R Lejmi-Mrad; Eric C LaCasse; S D Baird; David F Stojdl; R A Screaton; Robert G Korneluk
SMG1 and NIK regulate apoptosis induced by Smac mimetic compounds.
Cell death & disease 2011;2():e146.
2010: Herman H Cheung; Shawn T Beug; Martine St Jean; Audrey Brewster; N Lynn Kelly; Shaomeng Wang; Robert G Korneluk
Smac mimetic compounds potentiate interleukin-1beta-mediated cell death.
The Journal of biological chemistry 2010;285(52):40612-23.
2010: Jian Wang; Trevor Menchenton; Shankai Yin; Zhiping Yu; Manohar Bance; David P Morris; Craig S Moore; Robert G Korneluk; George S Robertson
Over-expression of X-linked inhibitor of apoptosis protein slows presbycusis in C57BL/6J mice.
Neurobiology of aging 2010;31(7):1238-49.
2010: Shui Ping Tu; Yun Wei Sun; Jian Tao Cui; Bing Zou; Marie C M Lin; Qing Gu; Shi Hu Jiang; Hsiang-Fu Kung; Robert G Korneluk; Benjamin C Y Wong
Tumor suppressor XIAP-Associated factor 1 (XAF1) cooperates with tumor necrosis factor-related apoptosis-inducing ligand to suppress colon cancer growth and trigger tumor regression.
Cancer 2010;116(5):1252-63.
2010: Annette Plesner; Galina Soukhatcheva; Robert G Korneluk; C Bruce Verchere
XIAP inhibition of β-cell apoptosis reduces the number of islets required to restore euglycemia in a syngeneic islet transplantation model.
Islets 2010;2(1):18-23.
2009: Herman H Cheung; Douglas J Mahoney; Eric C LaCasse; Robert G Korneluk
Down-regulation of c-FLIP Enhances death of cancer cells by smac mimetic compound.
Cancer research 2009;69(19):7729-38.
2009: Shui Ping Tu; Peter Liston; Jian Tao Cui; Marie C M Lin; Xiao Hua Jiang; Yi Yang; Qing Gu; Shi Hu Jiang; Ching Tung Lum; Hsiang-Fu Kung; Robert G Korneluk; Benjamin Chun-Yu Wong
Restoration of XAF1 expression induces apoptosis and inhibits tumor growth in gastric cancer.
International journal of cancer. Journal international du cancer 2009;125(3):688-97.
2009: Mathieu J M Bertrand; Karine Doiron; Katherine Labbé; Robert G Korneluk; Philip A Barker; Maya Saleh
Cellular inhibitors of apoptosis cIAP1 and cIAP2 are required for innate immunity signaling by the pattern recognition receptors NOD1 and NOD2.
Immunity 2009;30(6):789-801.
2008: Brian J Zarnegar; Yaya Wang; Douglas J Mahoney; Paul W Dempsey; Herman H Cheung; Jeannie He; Travis Shiba; Xiaolu Yang; Wen-Chen Yeh; Tak W Mak; Robert G Korneluk; Genhong Cheng
Noncanonical NF-kappaB activation requires coordinated assembly of a regulatory complex of the adaptors cIAP1, cIAP2, TRAF2 and TRAF3 and the kinase NIK.
Nature immunology 2008;9(12):1371-8.
2008: Eric C LaCasse; D J Mahoney; Herman H Cheung; Stéphanie Plenchette; S Baird; Robert G Korneluk
IAP-targeted therapies for cancer.
Oncogene 2008;27(48):6252-75.
2008: Craig S Moore; Andrea L O Hebb; Mathieu M Blanchard; Candice E Crocker; Peter Liston; Robert G Korneluk; George S Robertson
Increased X-linked inhibitor of apoptosis protein (XIAP) expression exacerbates experimental autoimmune encephalomyelitis (EAE).
Journal of neuroimmunology 2008;203(1):79-93.
2008: D J Mahoney; Herman H Cheung; R Lejmi Mrad; Stéphanie Plenchette; C Simard; E Enwere; V Arora; T W Mak; Eric C LaCasse; J Waring; Robert G Korneluk
Both cIAP1 and cIAP2 regulate TNFalpha-mediated NF-kappaB activation.
Proceedings of the National Academy of Sciences of the United States of America 2008;105(33):11778-83.
2008: Herman H Cheung; Stéphanie Plenchette; Chris J Kern; Douglas J Mahoney; Robert G Korneluk
The RING domain of cIAP1 mediates the degradation of RING-bearing inhibitor of apoptosis proteins by distinct pathways.
Molecular biology of the cell 2008;19(7):2729-40.
2007: Vinay Arora; Herman H Cheung; Stéphanie Plenchette; O Cristina Micali; Peter Liston; Robert G Korneluk
Degradation of survivin by the X-linked inhibitor of apoptosis (XIAP)-XAF1 complex.
The Journal of biological chemistry 2007;282(36):26202-9.
2007: Allison M Hunter; Eric C LaCasse; Robert G Korneluk
The inhibitors of apoptosis (IAPs) as cancer targets.
Apoptosis : an international journal on programmed cell death 2007;12(9):1543-68.
2007: Stéphanie Plenchette; Herman H Cheung; Wai Gin Fong; Eric C LaCasse; Robert G Korneluk
The role of XAF1 in cancer.
Current opinion in investigational drugs (London, England : 2000) 2007;8(6):469-76.
2007: O Cristina Micali; Herman H Cheung; Stéphanie Plenchette; Sandra L Hurley; Peter Liston; Eric C LaCasse; Robert G Korneluk
Silencing of the XAF1 gene by promoter hypermethylation in cancer cells and reactivation to TRAIL-sensitization by IFN-beta.
BMC cancer 2007;7():52.
2007: Kevin C Leonard; Dino Petrin; Stuart G Coupland; Adam N Baker; Brian C Leonard; Eric C LaCasse; William W Hauswirth; Robert G Korneluk; Catherine Tsilfidis
XIAP protection of photoreceptors in animal models of retinitis pigmentosa.
PloS one 2007;2(3):e314.
2006: Zaiping Liu; Hongbing Li; Xue Wu; B H Yoo; Sen Rong Yan; Andrew W Stadnyk; Takehiko Sasazuki; Senji Shirasawa; Eric C LaCasse; Robert G Korneluk; Kirill Rosen
Detachment-induced upregulation of XIAP and cIAP2 delays anoikis of intestinal epithelial cells.
Oncogene 2006;25(59):7680-90.
2006: Stephen D Baird; Marcel Turcotte; Robert G Korneluk; Martin Holcik
Searching for IRES.
RNA (New York, N.Y.) 2006;12(10):1755-85.
2006: Herman H Cheung; N Lynn Kelly; Peter Liston; Robert G Korneluk
Involvement of caspase-2 and caspase-9 in endoplasmic reticulum stress-induced apoptosis: a role for the IAPs.
Experimental cell research 2006;312(12):2347-57.
2006: Dina Shafey; Robert G Korneluk; Martin Holcik
Distinct patterns of expression of the inhibitor of apoptosis protein cIAP2 during murine embryogenesis.
Apoptosis : an international journal on programmed cell death 2006;11(7):1257-9.
2006: Herman H Cheung; Eric C LaCasse; Robert G Korneluk
X-linked inhibitor of apoptosis antagonism: strategies in cancer treatment.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(11 Pt 1):3238-42.
2006: J Renwick; Monica Narang; Stuart G Coupland; JY Xuan; A N Baker; J Brousseau; Dino Petrin; R Munger; Brian C Leonard; William W Hauswirth; Robert G Korneluk; Catherine Tsilfidis
XIAP-mediated neuroprotection in retinal ischemia.
Gene therapy 2006;13(4):339-47.
2006: Herman H Cheung; Vinay Arora; Robert G Korneluk
Abnormalities of cell structures in tumors: apoptosis in tumors.
EXS 2006;(96):201-21.
2006: Damiano Conte; Martin Holcik; Charles A Lefebvre; Eric C LaCasse; David J Picketts; Kathryn E Wright; Robert G Korneluk
Inhibitor of apoptosis protein cIAP2 is essential for lipopolysaccharide-induced macrophage survival.
Molecular and cellular biology 2006;26(2):699-708.
2005: Zaiping Liu; Hongbing Li; Mathieu Derouet; Jorge Filmus; Eric C LaCasse; Robert G Korneluk; Robert S Kerbel; Kirill Rosen
ras Oncogene triggers up-regulation of cIAP2 and XIAP in intestinal epithelial cells: epidermal growth factor receptor-dependent and -independent mechanisms of ras-induced transformation.
The Journal of biological chemistry 2005;280(45):37383-92.
2005: Juliet A Emamaullee; Ray V Rajotte; Peter Liston; Robert G Korneluk; Jonathan R T Lakey; A M James Shapiro; John Elliott
XIAP overexpression in human islets prevents early posttransplant apoptosis and reduces the islet mass needed to treat diabetes.
Diabetes 2005;54(9):2541-8.
2005: Annette Plesner; Peter Liston; Rusung Tan; Robert G Korneluk; C Bruce Verchere
The X-linked inhibitor of apoptosis protein enhances survival of murine islet allografts.
Diabetes 2005;54(9):2533-40.
2005: Juliet A Emamaullee; Peter Liston; Robert G Korneluk; A M James Shapiro; John Elliott
XIAP overexpression in islet beta-cells enhances engraftment and minimizes hypoxia-reperfusion injury.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(6):1297-305.
2005: Dawei Ou; Xiaojie Wang; Daniel L Metzger; Roger F L James; Paolo Pozzilli; Annette Plesner; Robert G Korneluk; C Bruce Verchere; Aubrey J Tingle
Synergistic inhibition of tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in human pancreatic beta cells by Bcl-2 and X-linked inhibitor of apoptosis.
Human immunology 2005;66(3):274-84.
2004: Daniel Perrelet; Florence E Perrin; Peter Liston; Robert G Korneluk; Alex MacKenzie; Marcel Ferrer-Alcon; Ann C Kato
Motoneuron resistance to apoptotic cell death in vivo correlates with the ratio between X-linked inhibitor of apoptosis proteins (XIAPs) and its inhibitor, XIAP-associated factor 1.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2004;24(15):3777-85.
2004: Christopher J Storbeck; Kate Daniel; Yi-Hong Zhang; John A Lunde; Anthony Scime; Atsushi Asakura; Bernard J Jasmin; Robert G Korneluk; Luc A Sabourin
Ste20-like kinase SLK displays myofiber type specificity and is involved in C2C12 myoblast differentiation.
Muscle & nerve 2004;29(4):553-64.
2004: Christopher J Storbeck; Suzana Drmanic; Kate Daniel; James D Waring; Frank R Jirik; David J Parry; Nazim Ahmed; Luc A Sabourin; Joh-E Ikeda; Robert G Korneluk
Inhibition of myogenesis in transgenic mice expressing the human DMPK 3'-UTR.
Human molecular genetics 2004;13(6):589-600.
2003: Peter Liston; Wai Gin Fong; Robert G Korneluk
The inhibitors of apoptosis: there is more to life than Bcl2.
Oncogene 2003;22(53):8568-80.
2003: YanPing Hu; Gabriele Cherton-Horvat; Visia Dragowska; Stephen Baird; Robert G Korneluk; Jon Durkin; Lawrence D Mayer; Eric C LaCasse
Antisense oligonucleotides targeting XIAP induce apoptosis and enhance chemotherapeutic activity against human lung cancer cells in vitro and in vivo.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(7):2826-36.
2003: Dino Petrin; Adam Baker; Stuart G Coupland; Peter Liston; Monica Narang; Karim F Damji; Brian Leonard; Vince A Chiodo; Adrian Timmers; William W Hauswirth; Robert G Korneluk; Catherine Tsilfidis
Structural and functional protection of photoreceptors from MNU-induced retinal degeneration by the X-linked inhibitor of apoptosis.
Investigative ophthalmology & visual science 2003;44(6):2757-63.
2003: Stephen J Crocker; Peter Liston; Hymie Anisman; C J Lee; Patrice D Smith; N Earl; Charlie S Thompson; David Park; Robert G Korneluk; George S Robertson
Attenuation of MPTP-induced neurotoxicity and behavioural impairment in NSE-XIAP transgenic mice.
Neurobiology of disease 2003;12(2):150-61.
2003: Ing Swie Goping; Michele Barry; Peter Liston; Tracy Sawchuk; Gabriela Constantinescu; Karolina M Michalak; Irene Shostak; Darren L Roberts; Allison M Hunter; Robert G Korneluk; R Chris Bleackley
Granzyme B-induced apoptosis requires both direct caspase activation and relief of caspase inhibition.
Immunity 2003;18(3):355-65.
2003: Allison M Hunter; Dan Kottachchi; Jennifer Lewis; Colin S Duckett; Robert G Korneluk; Peter Liston
A novel ubiquitin fusion system bypasses the mitochondria and generates biologically active Smac/DIABLO.
The Journal of biological chemistry 2003;278(9):7494-9.
2003: Tara A Nevins; Zdena M Harder; Robert G Korneluk; Martin Holcík
Distinct regulation of internal ribosome entry site-mediated translation following cellular stress is mediated by apoptotic fragments of eIF4G translation initiation factor family members eIF4GI and p97/DAP5/NAT1.
The Journal of biological chemistry 2003;278(6):3572-9.
2003: Martin Holcík; Bruce W Gordon; Robert G Korneluk
The internal ribosome entry site-mediated translation of antiapoptotic protein XIAP is modulated by the heterogeneous nuclear ribonucleoproteins C1 and C2.
Molecular and cellular biology 2003;23(1):280-8.
2002: Stuart J McKinnon; Donna Lehman; N Grace Tahzib; Nancy L Ransom; Herbert A Reitsamer; Peter Liston; Eric C LaCasse; Qiuhong Li; Robert G Korneluk; William W Hauswirth
Baculoviral IAP repeat-containing-4 protects optic nerve axons in a rat glaucoma model.
Molecular therapy : the journal of the American Society of Gene Therapy 2002;5(6):780-7.
2002: Daniel Perrelet; Anna Ferri; Peter Liston; P Muzzin; Robert G Korneluk; Ann C Kato
IAPs are essential for GDNF-mediated neuroprotective effects in injured motor neurons in vivo.
Nature cell biology 2002;4(2):175-9.
2002: Martin Holcik; Charles A Lefebvre; Keiko Hicks; Robert G Korneluk
Cloning and characterization of the rat homologues of the Inhibitor of Apoptosis protein 1, 2, and 3 genes.
BMC genomics 2002;3():5.
2001: Martine Lagacé; JY Xuan; S S Young; C McRoberts; J Maier; E Rajcan-Separovic; Robert G Korneluk
Genomic organization of the X-linked inhibitor of apoptosis and identification of a novel testis-specific transcript.
Genomics 2001;77(3):181-8.
2001: Martin Holcik; H Gibson; Robert G Korneluk
XIAP: apoptotic brake and promising therapeutic target.
Apoptosis : an international journal on programmed cell death 2001;6(4):253-61.
2001: Stephen J Crocker; N Wigle; Peter Liston; Charlie S Thompson; C J Lee; D Xu; S Roy; Donald W Nicholson; David Park; Alex Mackenzie; Robert G Korneluk; George S Robertson
NAIP protects the nigrostriatal dopamine pathway in an intrastriatal 6-OHDA rat model of Parkinson's disease.
The European journal of neuroscience 2001;14(2):391-400.
2001: Martin Holcik; Robert G Korneluk
XIAP, the guardian angel.
Nature reviews. Molecular cell biology 2001;2(7):550-6.
2001: LC Surh; M Mahadevan; Robert G Korneluk
Analysis of trinucleotide repeats in myotonic dystrophy.
Current protocols in human genetics / editorial board, Jonathan L. Haines ... [et al.] 2001;Chapter 9():Unit 9.6.
2001: D Conte; Peter Liston; J W Wong; K E Wright; Robert G Korneluk
Thymocyte-targeted overexpression of xiap transgene disrupts T lymphoid apoptosis and maturation.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(9):5049-54.
2001: Peter Liston; Wai Gin Fong; N L Kelly; S Toji; T Miyazaki; D Conte; Katsuyuki Tamai; C G Craig; M W McBurney; Robert G Korneluk
Identification of XAF1 as an antagonist of XIAP anti-Caspase activity.
Nature cell biology 2001;3(2):128-33.
2001: J Li; Q Feng; J M Kim; D Schneiderman; Peter Liston; M Li; Barbara C Vanderhyden; Wylam Faught; Michael Fung Kee Fung; Mary Senterman; Robert G Korneluk; Benjamin K Tsang
Human ovarian cancer and cisplatin resistance: possible role of inhibitor of apoptosis proteins.
Endocrinology 2001;142(1):370-80.
2000: Wai Gin Fong; Peter Liston; E Rajcan-Separovic; Martine St-Jean; C Craig; Robert G Korneluk
Expression and genetic analysis of XIAP-associated factor 1 (XAF1) in cancer cell lines.
Genomics 2000;70(1):113-22.
2000: Martin Holcik; N Sonenberg; Robert G Korneluk
Internal ribosome initiation of translation and the control of cell death.
Trends in genetics : TIG 2000;16(10):469-73.
2000: Martin Holcik; C Yeh; Robert G Korneluk; T Chow
Translational upregulation of X-linked inhibitor of apoptosis (XIAP) increases resistance to radiation induced cell death.
Oncogene 2000;19(36):4174-7.
2000: Monica Narang; James D Waring; Luc A Sabourin; Robert G Korneluk
Myotonic dystrophy (DM) protein kinase levels in congenital and adult DM patients.
European journal of human genetics : EJHG 2000;8(7):507-12.
2000: Martin Holcik; Robert G Korneluk
Functional characterization of the X-linked inhibitor of apoptosis (XIAP) internal ribosome entry site element: role of La autoantigen in XIAP translation.
Molecular and cellular biology 2000;20(13):4648-57.
2000: Daniel Perrelet; Anna Ferri; Alex E MacKenzie; G M Smith; Robert G Korneluk; Peter Liston; Y Sagot; J Terrado; D Monnier; Ann C Kato
IAP family proteins delay motoneuron cell death in vivo.
The European journal of neuroscience 2000;12(6):2059-67.
2000: Martin Holcik; C S Thompson; Zahra Yaraghi; Charles A Lefebvre; Alex E MacKenzie; Robert G Korneluk
The hippocampal neurons of neuronal apoptosis inhibitory protein 1 (NAIP1)-deleted mice display increased vulnerability to kainic acid-induced injury.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(5):2286-90.
1999: J Tran; Janusz Rak; C Sheehan; S D Saibil; Eric C LaCasse; Robert G Korneluk; Robert S Kerbel
Marked induction of the IAP family antiapoptotic proteins survivin and XIAP by VEGF in vascular endothelial cells.
Biochemical and biophysical research communications 1999;264(3):781-8.
1999: Martin Holcik; C Lefebvre; C Yeh; T Chow; Robert G Korneluk
A new internal-ribosome-entry-site motif potentiates XIAP-mediated cytoprotection.
Nature cell biology 1999;1(3):190-2.
1999: D Xu; Yves Bureau; Dan C McIntyre; Donald W Nicholson; Peter Liston; Y Zhu; Wai Gin Fong; Stephen J Crocker; Robert G Korneluk; George S Robertson
Attenuation of ischemia-induced cellular and behavioral deficits by X chromosome-linked inhibitor of apoptosis protein overexpression in the rat hippocampus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(12):5026-33.
1999: B Wagenknecht; T Glaser; Ulrike Naumann; Sebastian Kügler; Stefan Isenmann; M Bähr; Robert G Korneluk; Peter Liston; M Weller
Expression and biological activity of X-linked inhibitor of apoptosis (XIAP) in human malignant glioma.
Cell death and differentiation 1999;6(4):370-6.
1999: S S Young; Peter Liston; JY Xuan; C McRoberts; Charles A Lefebvre; Robert G Korneluk
Genomic organization and physical map of the human inhibitors of apoptosis: HIAP1 and HIAP2.
Mammalian genome : official journal of the International Mammalian Genome Society 1999;10(1):44-8.
1999: M Simons; S Beinroth; Marc Gleichmann; Peter Liston; Robert G Korneluk; Alex E MacKenzie; Mathias Bähr; Thomas Klockgether; G S Robertson; Michael Weller; Jörg B Schulz
Adenovirus-mediated gene transfer of inhibitors of apoptosis protein delays apoptosis in cerebellar granule neurons.
Journal of neurochemistry 1999;72(1):292-301.
1998: Eric C LaCasse; S Baird; Robert G Korneluk; Alex E MacKenzie
The inhibitors of apoptosis (IAPs) and their emerging role in cancer.
Oncogene 1998;17(25):3247-59.
1998: Zahra Yaraghi; Robert G Korneluk; Alex Mackenzie
Cloning and characterization of the multiple murine homologues of NAIP (neuronal apoptosis inhibitory protein).
Genomics 1998;51(1):107-13.
1998: Christopher J Storbeck; Luc A Sabourin; James D Waring; Robert G Korneluk
Definition of regulatory sequence elements in the promoter region and the first intron of the myotonic dystrophy protein kinase gene.
The Journal of biological chemistry 1998;273(15):9139-47.
1998: J Li; JM Kim; Peter Liston; M Li; T Miyazaki; Alex E MacKenzie; Robert G Korneluk; Benjamin K Tsang
Expression of inhibitor of apoptosis proteins (IAPs) in rat granulosa cells during ovarian follicular development and atresia.
Endocrinology 1998;139(3):1321-8.
1998: Q Chen; S D Baird; M Mahadevan; A Besner-Johnston; R Farahani; J Xuan; X Kang; C Lefebvre; Joh-E Ikeda; Robert G Korneluk; Alex E MacKenzie
Sequence of a 131-kb region of 5q13.1 containing the spinal muscular atrophy candidate genes SMN and NAIP.
Genomics 1998;48(1):121-7.
1998: E Rajcan-Separovic; J M Barcelo; Robert G Korneluk
Fluorescence in situ hybridization analysis of the replication properties of the myotonic dystrophy protein kinase (DMPK) gene region.
Cytogenetics and cell genetics 1998;82(3-4):247-50.
1998: James D Waring; Robert G Korneluk
Myotonic dystrophy.
Results and problems in cell differentiation 1998;21():77-131.
1997: Peter Liston; C Lefebvre; Wai Gin Fong; JY Xuan; Robert G Korneluk
Genomic characterization of the mouse inhibitor of apoptosis protein 1 and 2 genes.
Genomics 1997;46(3):495-503.
1997: Luc A Sabourin; K Tamai; Monica Narang; Robert G Korneluk
Overexpression of 3'-untranslated region of the myotonic dystrophy kinase cDNA inhibits myoblast differentiation in vitro.
The Journal of biological chemistry 1997;272(47):29626-35.
1997: Ronald G Lafrenière; Zoha Kibar; Daniel Rochefort; Fei-Yu Han; Edward A Fon; Marie-Pierre Dubé; X Kang; S Baird; Robert G Korneluk; Johanna M Rommens; Guy Rouleau
Genomic structure of the human GT334 (EHOC-1) gene mapping to 21q22.3.
Gene 1997;198(1-2):313-21.
1997: DG Xu; Stephen J Crocker; JP Doucet; Martine St-Jean; K Tamai; Antoine M Hakim; Joh-E Ikeda; Peter Liston; Charlie S Thompson; Robert G Korneluk; Alex Mackenzie; George S Robertson
Elevation of neuronal expression of NAIP reduces ischemic damage in the rat hippocampus.
Nature medicine 1997;3(9):997-1004.
1997: R Farahani; Wai Gin Fong; Robert G Korneluk; Alex E MacKenzie
Genomic organization and primary characterization of miap-3: the murine homologue of human X-linked IAP.
Genomics 1997;42(3):514-8.
1997: DG Xu; Robert G Korneluk; Katsuyuki Tamai; N Wigle; A Hakim; Alex Mackenzie; George S Robertson
Distribution of neuronal apoptosis inhibitory protein-like immunoreactivity in the rat central nervous system.
The Journal of comparative neurology 1997;382(2):247-59.
1997: R J Hawley; John A Colleran; Robert G Korneluk; L C Surh
Correlation between decreased myocardial glucose phosphorylation and DNA mutation size in myotonic dystrophy.
Circulation 1997;95(6):1664-5.
1997: M J Somerville; Alasdair G W Hunter; H L Aubry; Robert G Korneluk; Alex E MacKenzie; LC Surh
Clinical application of the molecular diagnosis of spinal muscular atrophy: deletions of neuronal apoptosis inhibitor protein and survival motor neuron genes.
American journal of medical genetics 1997;69(2):159-65.
1997: Robert G Korneluk; Monica Narang
Anticipating anticipation.
Nature genetics 1997;15(2):119-20.
1997: Peter Liston; S S Young; Alex E MacKenzie; Robert G Korneluk
Life and death decisions: the role of the IAPs in modulating programmed cell death.
Apoptosis : an international journal on programmed cell death 1997;2(5):423-41.
1996: E Rajcan-Separovic; Peter Liston; C Lefebvre; Robert G Korneluk
Assignment of human inhibitor of apoptosis protein (IAP) genes xiap, hiap-1, and hiap-2 to chromosomes Xq25 and 11q22-q23 by fluorescence in situ hybridization.
Genomics 1996;37(3):404-6.
1996: Q Chen; C Neville; A MacKenzie; Robert G Korneluk
Automated DNA sequencing requiring no DNA template purification.
BioTechniques 1996;21(3):453-7.
1996: H Yokoi; Y Shimizu; Hideharu Anazawa; C A Lefebvre; Robert G Korneluk; J E Ikeda
The structure and complete nucleotide sequence of the human cyclophilin 40 (PPID) gene.
Genomics 1996;35(3):448-55.
1996: J D Waring; R Haq; Katsuyuki Tamai; Luc A Sabourin; Joh-E Ikeda; Robert G Korneluk
Investigation of myotonic dystrophy kinase isoform translocation and membrane association.
The Journal of biological chemistry 1996;271(25):15187-93.
1996: G Shutler; T Glassco; X Kang; Robert G Korneluk; C R Mueller
Genomic structure of the human D-site binding protein (DBP) gene.
Genomics 1996;34(3):334-9.
1996: Peter Liston; N Roy; Katsuyuki Tamai; C Lefebvre; S Baird; G Cherton-Horvat; R Farahani; M McLean; Joh-E Ikeda; Alex Mackenzie; Robert G Korneluk
Suppression of apoptosis in mammalian cells by NAIP and a related family of IAP genes.
Nature 1996;379(6563):349-53.
1996: E Rajcan-Separovic; M S Mahadevan; C Lefebvre; A Besner-Johnston; Joh-E Ikeda; Robert G Korneluk; Alex Mackenzie
FISH detection of chromosome polymorphism and deletions in the spinal muscular atrophy (SMA) region of 5q13.
Cytogenetics and cell genetics 1996;75(4):243-7.
1996: S Cheng; J M Barceló; Robert G Korneluk
Characterization of large CTG repeat expansions in myotonic dystrophy alleles using PCR.
Human mutation 1996;7(4):304-10.
1995: M S Mahadevan; S Baird; J E Bailly; G G Shutler; Luc A Sabourin; C Tsilfidis; C E Neville; Monica Narang; Robert G Korneluk
Isolation of a novel G protein-coupled receptor (GPR4) localized to chromosome 19q13.3.
Genomics 1995;30(1):84-8.
1995: Z Yaraghi; M D McLean; N Roy; LC Surh; Joh-E Ikeda; Robert G Korneluk; Alex Mackenzie
A recombination event occurring within two complex 5q13.1 microsatellite repeat polymorphisms suggests a telomeric mapping of spinal muscular atrophy.
Human genetics 1995;96(3):330-4.
1995: E Rajcan-Separovic; H S Wang; Marsha Speevak; L Janes; Robert G Korneluk; K Wakasa; Joh-E Ikeda
Identification of the origin of double minutes in normal human cells by laser-based chromosome microdissection approach.
Human genetics 1995;96(1):39-43.
1995: E J Whiting; J D Waring; Katsuyuki Tamai; M J Somerville; Maxwell T Hincke; W A Staines; Joh-E Ikeda; Robert G Korneluk
Characterization of myotonic dystrophy kinase (DMK) protein in human and rodent muscle and central nervous tissue.
Human molecular genetics 1995;4(6):1063-72.
1995: N Roy; M D McLean; A Besner-Johnston; C Lefebvre; M Salih; J D Carpten; Arthur H M Burghes; Z Yaraghi; Joh-E Ikeda; Robert G Korneluk
Refined physical map of the spinal muscular atrophy gene (SMA) region at 5q13 based on YAC and cosmid contiguous arrays.
Genomics 1995;26(3):451-60.
1995: E J Whiting; C Tsilfidis; LC Surh; Alex E MacKenzie; Robert G Korneluk
Convergent myotonic dystrophy (DM) haplotypes: potential inconsistencies in human disease gene localization.
European journal of human genetics : EJHG 1995;3(3):195-202.
1994: M D McLean; N Roy; Alex E MacKenzie; M Salih; Arthur H M Burghes; Louise R Simard; Robert G Korneluk; Joh-E Ikeda; LC Surh
Two 5q13 simple tandem repeat loci are in linkage disequilibrium with type 1 spinal muscular atrophy.
Human molecular genetics 1994;3(11):1951-6.
1994: J M Barceló; M Pluscauskas; Alex E MacKenzie; C Tsilfidis; Monica Narang; Robert G Korneluk
Additive influence of maternal and offspring DM-kinase gene CTG repeat lengths in the genesis of congenital myotonic dystrophy.
American journal of human genetics 1994;54(6):1124-5.
1994: G G Shutler; Alex E MacKenzie; Robert G Korneluk
The 1.5-Mb region spanning the myotonic dystrophy locus shows uniform recombination frequency.
American journal of human genetics 1994;54(1):104-13.
1994: C E Neville; M S Mahadevan; J M Barceló; Robert G Korneluk
High resolution genetic analysis suggests one ancestral predisposing haplotype for the origin of the myotonic dystrophy mutation.
Human molecular genetics 1994;3(1):45-51.
1993: L A Sabouri; M S Mahadevan; Monica Narang; D S Lee; LC Surh; Robert G Korneluk
Effect of the myotonic dystrophy (DM) mutation on mRNA levels of the DM gene.
Nature genetics 1993;4(3):233-8.
1993: J M Barceló; M S Mahadevan; C Tsilfidis; Alex E MacKenzie; Robert G Korneluk
Intergenerational stability of the myotonic dystrophy protomutation.
Human molecular genetics 1993;2(6):705-9.
1993: K L O'Hoy; C Tsilfidis; M S Mahadevan; C E Neville; J Barceló; Alasdair G W Hunter; Robert G Korneluk
Reduction in size of the myotonic dystrophy trinucleotide repeat mutation during transmission.
Science (New York, N.Y.) 1993;259(5096):809-12.
1993: M S Mahadevan; M A Foitzik; LC Surh; Robert G Korneluk
Characterization and polymerase chain reaction (PCR) detection of an Alu deletion polymorphism in total linkage disequilibrium with myotonic dystrophy.
Genomics 1993;15(2):446-8.
1993: Alasdair G W Hunter; P Jacob; K O'Hoy; I MacDonald; G Mettler; C Tsilfidis; Robert G Korneluk
Decrease in the size of the myotonic dystrophy CTG repeat during transmission from parent to child: implications for genetic counselling and genetic anticipation.
American journal of medical genetics 1993;45(3):401-7.
1993: Alex Mackenzie; N Roy; A Besner; G Mettler; P Jacob; Robert G Korneluk; LC Surh
Genetic linkage analysis of Canadian spinal muscular atrophy kindreds using flanking microsatellite 5q13 polymorphisms.
Human genetics 1993;90(5):501-4.
1992: A Hunter; C Tsilfidis; G Mettler; P Jacob; M Mahadevan; LC Surh; Robert G Korneluk
The correlation of age of onset with CTG trinucleotide repeat amplification in myotonic dystrophy.
Journal of medical genetics 1992;29(11):774-9.
1992: G Shutler; Robert G Korneluk; C Tsilfidis; M Mahadevan; J Bailly; H Smeets; G Jansen; B Wieringa; F Lohman; C Aslanidis
Physical mapping and cloning of the proximal segment of the myotonic dystrophy gene region.
Genomics 1992;13(3):518-25.
1992: G Jansen; P J de Jong; C Amemiya; C Aslanidis; D J Shaw; H G Harley; J David Brook; R Fenwick; Robert G Korneluk; C Tsilfidis
Physical and genetic characterization of the distal segment of the myotonic dystrophy area on 19q.
Genomics 1992;13(3):509-17.
1992: C Tsilfidis; Alex E MacKenzie; G Mettler; J Barceló; Robert G Korneluk
Correlation between CTG trinucleotide repeat length and frequency of severe congenital myotonic dystrophy.
Nature genetics 1992;1(3):192-5.
1991: LC Surh; G G Shutler; Robert G Korneluk
Simple, rapid detection of PCR heteroduplexes in DNA mutations and polymorphisms.
Clinical chemistry 1991;37(12):2142.
1991: C Tsilfidis; Alex E MacKenzie; G Shutler; S Leblond; J Bailly; keith jack johnson; R Williamson; J Siegel-Bartelt; Robert G Korneluk; P Shelbourne
D19S51 is closely linked with and maps distal to the myotonic dystrophy locus on 19q.
American journal of human genetics 1991;49(5):961-5.
1991: Alex E MacKenzie; G Allen; D Lahey; M L Crossan; K Nolan; G Mettler; R G Worton; D H MacLennan; Robert G Korneluk
A comparison of the caffeine halothane muscle contracture test with the molecular genetic diagnosis of malignant hyperthermia.
Anesthesiology 1991;75(1):4-8.
1991: G Shutler; S Leblond; J Bailly; Alex E MacKenzie; C Tsilfidis; Robert G Korneluk
An insertion polymorphism identified by the probe pE0.8 (D19S115) at 19q13.3.
Nucleic acids research 1991;19(5):1159.
1991: G Shutler; C Tsilfidis; S Leblond; Robert G Korneluk
RFLP identified by the probe pKE0.6 (D19S117) at human chromosome 19q13.3.
Nucleic acids research 1991;19(5):1158.
1991: C Tsilfidis; G Shutler; S Leblond; Robert G Korneluk
An SstI RFLP detected by the probe pKE2.1 (D19S116) localized to human chromosome 19q13.3.
Nucleic acids research 1991;19(5):1158.
1991: Robert G Korneluk; C Tsilfidis; G Shutler; M Mahadevan; J Bailly; LC Surh
A three allele insertion polymorphism is identified by the human chromosome 19q13.3 probe pKBE0.8 (D19S119).
Nucleic acids research 1991;19(5):1157.
1991: C Tsilfidis; G Shutler; M Mahadevan; Robert G Korneluk
A frequent HincII polymorphism identified by the human chromosome 19q13.3 probe pKEX0.8 (D19S118).
Nucleic acids research 1991;19(5):1157.
1991: J Bailly; Alex E MacKenzie; S Leblond; Robert G Korneluk
Assessment of a creatine kinase isoform M defect as a cause of myotonic dystrophy and the characterization of two novel CKMM polymorphisms.
Human genetics 1991;86(5):457-62.
1991: G Shutler; Alex E MacKenzie; H Brunner; B Wieringa; P de Jong; F P Lohman; S Leblond; J Bailly; Robert G Korneluk
Physical and genetic mapping of a novel chromosome 19 ERCC1 marker showing close linkage with myotonic dystrophy.
Genomics 1991;9(3):500-4.
1991: Alex E MacKenzie; H L MacLeod; S C Leblond; N Monteith; D Lahey; Robert G Korneluk
DNA polymorphism and linkage disequilibrium within the apolipoprotein CII locus on human chromosome 19.
Human heredity 1991;41(3):188-94.
1990: C Lavedan; C Duros; D Savoy; S Leblond; J Bailly; Robert G Korneluk; Claudine Junien
Direct haplotyping by double digestion of PCR-amplified creatine kinase (CKMM): application to myotonic dystrophy diagnosis.
Genomics 1990;8(4):739-40.
1990: Alex E MacKenzie; Robert G Korneluk; F Zorzato; J Fujii; M Phillips; D Iles; B Wieringa; S Leblond; J Bailly; Huntington F Willard
The human ryanodine receptor gene: its mapping to 19q13.1, placement in a chromosome 19 linkage group, and exclusion as the gene causing myotonic dystrophy.
American journal of human genetics 1990;46(6):1082-9.
1990: David H MacLennan; C Duff; F Zorzato; J Fujii; M Phillips; Robert G Korneluk; W Frodis; B A Britt; R G Worton
Ryanodine receptor gene is a candidate for predisposition to malignant hyperthermia.
Nature 1990;343(6258):559-61.
1989: Alex E MacKenzie; H L MacLeod; H M Heick; Robert G Korneluk
False positive results from the alanine loading test for ornithine carbamoyltransferase deficiency heterozygosity.
The Journal of pediatrics 1989;115(4):605-8.
1989: Robert G Korneluk; Alex E MacKenzie; Y Nakamura; I Dubé; P Jacob; Alasdair G W Hunter
A reordering of human chromosome 19 long-arm DNA markers and identification of markers flanking the myotonic dystrophy locus.
Genomics 1989;5(3):596-604.
1989: Robert G Korneluk; H L MacLeod; S Leblond; T W McKeithan; Alex E MacKenzie
A Bsu36I RFLP detected by the chromosome 19q probe p alpha.5B [D19S36].
Nucleic acids research 1989;17(14):5875.
1989: Robert G Korneluk; H L MacLeod; D Lahey; T W McKeithan; Alex E MacKenzie
A BanI polymorphism identified by the probe p alpha 1.4P at 19q13.1 [D19S37].
Nucleic acids research 1989;17(14):5874.
1989: Han G Brunner; Robert G Korneluk; M Coerwinkel-Driessen; A MacKenzie; H J M Smeets; H M Lambermon; BA van Oost; Bé Wieringa; Hans-Hilger Ropers
Myotonic dystrophy is closely linked to the gene for muscle-type creatine kinase (CKMM).
Human genetics 1989;81(4):308-10.
1989: Robert G Korneluk; H L MacLeod; T W McKeithan; J D Brooks; Alex E MacKenzie
A chromosome 19 clone from a translocation breakpoint shows close linkage and linkage disequilibrium with myotonic dystrophy.
Genomics 1989;4(2):146-51.
1989: Alex E MacKenzie; H L MacLeod; Alasdair G W Hunter; Robert G Korneluk
Linkage analysis of the apolipoprotein C2 gene and myotonic dystrophy on human chromosome 19 reveals linkage disequilibrium in a French-Canadian population.
American journal of human genetics 1989;44(1):140-7.
1987: Robert G Korneluk; H L MacLeod; S C Leblond; N L Monteith; F E Baralle; Alasdair G W Hunter
AvaII RFLP at the human apolipoprotein CII (APO CII) gene locus.
Nucleic acids research 1987;15(16):6769.
1986: F Quan; Robert G Korneluk; mike tropak; Roy A Gravel
Isolation and characterization of the human catalase gene.
Nucleic acids research 1986;14(13):5321-35.
1986: Robert G Korneluk; Don J Mahuran; K Neote; M H Klavins; B F O'Dowd; mike tropak; H F Willard; M J Anderson; J A Lowden; Roy A Gravel
Isolation of cDNA clones coding for the alpha-subunit of human beta-hexosaminidase. Extensive homology between the alpha- and beta-subunits and studies on Tay-Sachs disease.
The Journal of biological chemistry 1986;261(18):8407-13.
1985: F Quan; Robert G Korneluk; H L MacLeod; L C Tsui; Roy A Gravel
An RFLP associated with the human catalase gene.
Nucleic acids research 1985;13(22):8288.
1985: B F O'Dowd; F Quan; H F Willard; A M Lamhonwah; Robert G Korneluk; J A Lowden; Roy A Gravel; Don J Mahuran
Isolation of cDNA clones coding for the beta subunit of human beta-hexosaminidase.
Proceedings of the National Academy of Sciences of the United States of America 1985;82(4):1184-8.
1985: K S Guise; Robert G Korneluk; J Waye; A M Lamhonwah; F Quan; R Palmer; R E Ganschow; William S Sly; Roy A Gravel
Isolation and expression in Escherichia coli of a cDNA clone encoding human beta-glucuronidase.
Gene 1985;34(1):105-10.
1985: Robert G Korneluk; F Quan; Roy A Gravel
Rapid and reliable dideoxy sequencing of double-stranded DNA.
Gene 1985;40(2-3):317-23.
1984: Robert G Korneluk; F Quan; W H Lewis; K S Guise; H F Willard; M T Holmes; Roy A Gravel
Isolation of human fibroblast catalase cDNA clones. Sequence of clones derived from spliced and unspliced mRNA.
The Journal of biological chemistry 1984;259(22):13819-23.