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Timo Korpela

Research Profile

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Publications

TOP 3
Petri Susi; GE Aktuganov; Juha Himanen; Timo Korpela
Biological control of wood decay against fungal infection.
Vladimir Zav'yalov; Galina Zav'yalova; Andrey V Zavialov; Timo Korpela
Adhesive organelles of Gram-negative pathogens assembled with the classical chaperone/usher machinery: structure and function from a clinical standpoint.
Andrey V Zavialov; Galina Zav'yalova; Timo Korpela; Vladimir P Zav'yalov
FGL chaperone-assembled fimbrial polyadhesins: anti-immune armament of Gram-negative bacterial pathogens.

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All Publications

2011: Petri Susi; GE Aktuganov; Juha Himanen; Timo Korpela
Biological control of wood decay against fungal infection.
Journal of environmental management 2011;92(7):1681-9.
2010: Vladimir Zav'yalov; Galina Zav'yalova; Andrey V Zavialov; Timo Korpela
Adhesive organelles of Gram-negative pathogens assembled with the classical chaperone/usher machinery: structure and function from a clinical standpoint.
FEMS microbiology reviews 2010;34(3):317-78.
2007: Andrey V Zavialov; Galina Zav'yalova; Timo Korpela; Vladimir P Zav'yalov
FGL chaperone-assembled fimbrial polyadhesins: anti-immune armament of Gram-negative bacterial pathogens.
FEMS microbiology reviews 2007;31(4):478-514.
2006: Elena Dudich; Lidia Semenkova; Igor Dudich; Alexander I Denesyuk; Edward Tatulov; Timo Korpela
Alpha-fetoprotein antagonizes X-linked inhibitor of apoptosis protein anticaspase activity and disrupts XIAP-caspase interaction.
The FEBS journal 2006;273(16):3837-49.
2005: Elvira Khalikova; Petri Susi; Timo Korpela
Microbial dextran-hydrolyzing enzymes: fundamentals and applications.
Microbiology and molecular biology reviews : MMBR 2005;69(2):306-25.
2003: Elvira Khalikova; Petri Susi; Nikolai Usanov; Timo Korpela
Purification and properties of extracellular dextranase from a Bacillus sp.
Journal of chromatography. B, Analytical technologies in the biomedical and life sciences 2003;796(2):315-26.
2003: Lidia Semenkova; Elena Dudich; Igor Dudich; Natalie Tokhtamisheva; Edward Tatulov; Yury Okruzhnov; Jesus Garcia-Foncillas; Juan-Antonio Palop-Cubillo; Timo Korpela
Alpha-fetoprotein positively regulates cytochrome c-mediated caspase activation and apoptosome complex formation.
European journal of biochemistry / FEBS 2003;270(21):4388-99.
2003: Alexander I Denesyuk; Konstantin A Denessiouk; Timo Korpela; Mark S Johnson
Phosphate group binding "cup" of PLP-dependent and non-PLP-dependent enzymes: leitmotif and variations.
Biochimica et biophysica acta 2003;1647(1-2):234-8.
2003: Tony Wahlroos; Jori Soukka; Alexander I Denesyuk; Rina Wahlroos; Timo Korpela; Nigel J Kilby
Oleosin expression and trafficking during oil body biogenesis in tobacco leaf cells.
Genesis (New York, N.Y. : 2000) 2003;35(2):125-32.
2002: Andrey V Zavialov; Joanne E Kersley; Timo Korpela; Vladimir P Zav'yalov; Sheila MacIntyre; Stefan D Knight
Donor strand complementation mechanism in the biogenesis of non-pilus systems.
Molecular microbiology 2002;45(4):983-95.
2002: Alexander I Denesyuk; Konstantin A Denessiouk; Timo Korpela; Mark S Johnson
Functional attributes of the phosphate group binding cup of pyridoxal phosphate-dependent enzymes.
Journal of molecular biology 2002;316(1):155-72.
2001: P Helistö; GE Aktuganov; NF Galimzianova; A Melentjev; Timo Korpela
Lytic enzyme complex of an antagonistic Bacillus sp. X-b: isolation and purification of components.
Journal of chromatography. B, Biomedical sciences and applications 2001;758(2):197-205.
2001: Vyacheslav M Abramov; Anatoly M Vasiliev; Raisa N Vasilenko; Nataly L Kulikova; Igor V Kosarev; Valentin S Khlebnikov; A T Ishchenko; Sheila MacIntyre; Joel R Gillespie; Bhavana Shivu; Timo Korpela; Anthony L Fink; Vladimir Uversky
Structural and functional similarity between Yersinia pestis capsular protein Caf1 and human interleukin-1 beta.
Biochemistry 2001;40(20):6076-84.
2001: Zinaida I Kravchuk; Yaroslav I Tsybovsky; M Koivulehto; A Vlasov; Alexander A Chumanevich; Natalia Battchikova; Sergey P Martsev; Timo Korpela
Truncated aspartate aminotransferase from alkalophilic Bacillus circulans with deletion of N-terminal 32 amino acids is a non-functional monomer in a partially structured state.
Protein engineering 2001;14(4):279-85.
2001: Andrey V Zavialov; N V Batchikova; Timo Korpela; L E Petrovskaya; V G Korobko; Joanne E Kersley; S MacIntyre; Vladimir P Zav'yalov
Secretion of recombinant proteins via the chaperone/usher pathway in Escherichia coli.
Applied and environmental microbiology 2001;67(4):1805-14.
2000: Nina Hakulinen; S Paavilainen; Timo Korpela; Juha Rouvinen
The crystal structure of beta-glucosidase from Bacillus circulans sp. alkalophilus: ability to form long polymeric assemblies.
Journal of structural biology 2000;129(1):69-79.
1999: S Paavilainen; S Oinonen; Timo Korpela
Catabolic pathways of glucose in Bacillus circulans var. alkalophilus.
Extremophiles : life under extreme conditions 1999;3(4):269-76.
1999: Igor Dudich; N Tokhtamysheva; Lidia Semenkova; Elena Dudich; J Hellman; Timo Korpela
Isolation and structural and functional characterization of two stable peptic fragments of human alpha-fetoprotein.
Biochemistry 1999;38(32):10406-14.
1999: Konstantin A Denessiouk; Alexander I Denesyuk; Jukka V Lehtonen; Timo Korpela; Mark S Johnson
Common structural elements in the architecture of the cofactor-binding domains in unrelated families of pyridoxal phosphate-dependent enzymes.
Proteins 1999;35(2):250-61.
1998: Andrey V Zavialov; M Gaestel; Timo Korpela; Vladimir P Zav'yalov
Thiol/disulfide exchange between small heat shock protein 25 and glutathione.
Biochimica et biophysica acta 1998;1388(1):123-32.
1998: Alexander I Denesyuk; Konstantin A Denessiouk; Vladimir P Zav'yalov; J Lundell; Timo Korpela
Analogous conformations of both binding and effector regions in cyclosporin A, FK506 and rapamycin.
Computers & chemistry 1998;22(4):339-44.
1998: Konstantin A Denessiouk; Jukka V Lehtonen; Timo Korpela; Mark S Johnson
Two "unrelated" families of ATP-dependent enzymes share extensive structural similarities about their cofactor binding sites.
Protein science : a publication of the Protein Society 1998;7(5):1136-46.
1998: Alexander I Denesyuk; Vladimir P Zav'yalov; Konstantin A Denessiouk; Timo Korpela
Molecular models of two competitive inhibitors, IL-2delta2 and IL-2delta3, generated by alternative splicing of human interleukin-2.
Immunology letters 1998;60(2-3):61-6.
1997: Vladimir P Zav'yalov; Alexander I Denesyuk; Barbara A White; Vladimir V Yurovsky; Sergei Atamas; Timo Korpela
Molecular model of an alternative splice variant of human IL-4, IL-4 delta 2, a naturally occurring inhibitor of IL-4-stimulated T cell proliferation.
Immunology letters 1997;58(3):149-52.
1997: Vladimir P Zav'yalov; TV Chernovskaya; David A G Chapman; Andrey Karlyshev; Sheila MacIntyre; Andrey V Zavialov; Anatoly M Vasiliev; Alexander I Denesyuk; Galina A Zav'yalova; Igor Dudich; Timo Korpela; Vyacheslav M Abramov
Influence of the conserved disulphide bond, exposed to the putative binding pocket, on the structure and function of the immunoglobulin-like molecular chaperone Caf1M of Yersinia pestis.
The Biochemical journal 1997;324 ( Pt 2)():571-8.
1997: Heikki Peuravuori; R Kunelius; JU Eskola; Timo Korpela
Inorganic pyrophosphatase-labelled enzyme immunoassay for beta 2-microglobulin.
Journal of immunological methods 1997;204(2):161-7.
1996: N Battchikova; M Koivulehto; Alexander I Denesyuk; L Ptitsyn; Y Boretsky; Jukka Hellman; Timo Korpela
Aspartate aminotransferase from an alkalophilic Bacillus contains an additional 20-amino acid extension at its functionally important N-terminus.
Journal of biochemistry 1996;120(2):425-32.
1996: N Battchikova; Juha P Himanen; M Ahjolahti; Timo Korpela
Phosphoserine aminotransferase from Bacillus circulans subsp. alkalophilus: purification, gene cloning and sequencing.
Biochimica et biophysica acta 1996;1295(2):187-94.
1996: M Moser; R Müller; N Battchikova; M Koivulehto; Timo Korpela; Johan N Jansonius
Crystallization and preliminary X-ray analysis of phosphoserine aminotransferase from Bacillus circulans subsp. alkalophilus.
Protein science : a publication of the Protein Society 1996;5(7):1426-8.
1996: Alexander I Denesyuk; M S Johnson; Vladimir P Zav'yalov; Timo Korpela
Structure of cytokine hydrophobic cores.
Journal of theoretical biology 1996;180(4):297-307.
1996: Alexander I Denesyuk; S Matthews; Vladimir P Zav'yalov; Timo Korpela
Conservative hydrophobic interdomain contacts of IFN-gamma remain in P17 matrix protein of HIV-1.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1996;104(2):141-6.
1995: Igor Dudich; Vladimir P Zav'yalov; W Pfeil; M Gaestel; Galina A Zav'yalova; Alexander I Denesyuk; Timo Korpela
Dimer structure as a minimum cooperative subunit of small heat-shock proteins.
Biochimica et biophysica acta 1995;1253(2):163-8.
1995: Vladimir P Zav'yalov; Galina A Zav'yalova; Alexander I Denesyuk; M Gaestel; Timo Korpela
Structural and functional homology between periplasmic bacterial molecular chaperones and small heat shock proteins.
FEMS immunology and medical microbiology 1995;11(4):265-72.
1995: Vladimir P Zav'yalov; Alexander I Denesyuk; J Lundell; Timo Korpela
Some new aspects of molecular mechanisms of cyclosporin A effect on immune response.
APMIS : acta pathologica, microbiologica, et immunologica Scandinavica 1995;103(6):401-15.
1995: Vladimir P Zav'yalov; Galina A Zav'yalova; Alexander I Denesyuk; Timo Korpela
Modelling of steric structure of a periplasmic molecular chaperone Caf1M of Yersinia pestis, a prototype member of a subfamily with characteristic structural and functional features.
FEMS immunology and medical microbiology 1995;11(1):19-24.
1995: P Mattsson; N Battchikova; K Sippola; Timo Korpela
The role of histidine residues in the catalytic act of cyclomaltodextrin glucanotransferase from Bacillus circulans var. alkalophilus.
Biochimica et biophysica acta 1995;1247(1):97-103.
1995: Vladimir P Zav'yalov; Alexander I Denesyuk; Galina A Zav'yalova; Timo Korpela
Molecular modeling of the steric structure of the envelope F1 antigen of Yersinia pestis.
Immunology letters 1995;45(1-2):19-22.
1994: Alexander I Denesyuk; J Lundell; Vladimir P Zav'yalov; Timo Korpela
Cyclophilin A and an antibody against cyclosporin A resemble each other in their binding sites.
Immunology letters 1994;41(2-3):213-6.
1994: Alexander I Denesyuk; Vladimir P Zav'yalov; Timo Korpela
Modelling of interhelical contacts in interferons-beta, -gamma, and dimeric interleukin-5.
Biochemical and biophysical research communications 1994;201(3):1401-5.
1994: Alexander I Denesyuk; Vladimir P Zav'yalov; Timo Korpela
Common structural patterns of cytokine outer surfaces.
Biochemical and biophysical research communications 1994;201(3):1396-400.
1993: Alexander I Denesyuk; J Lundell; A Goldman; Vladimir P Zav'yalov; Timo Korpela
Structural repeats in cyclosporin A.
Biochemical and biophysical research communications 1993;197(3):1438-42.
1993: Alexander I Denesyuk; Timo Korpela; J Lundell; R Sara; Vladimir P Zav'yalov
Comparison of conformations of cyclosporin A and macrolide FK506 fragments: localization of putative binding sites with phosphatase calcineurin.
Biochemical and biophysical research communications 1993;194(1):280-6.
1993: Alexander I Denesyuk; Mauno Vihinen; J Lundell; Vladimir P Zav'yalov; Timo Korpela
Structural similarity of the binding sites of cyclophilin A-cyclosporin A and FKBP-FK506 systems.
Biochemical and biophysical research communications 1993;192(2):912-7.
1993: S Paavilainen; Jukka Hellman; Timo Korpela
Purification, characterization, gene cloning, and sequencing of a new beta-glucosidase from Bacillus circulans subsp. alkalophilus.
Applied and environmental microbiology 1993;59(3):927-32.
1992: N Belyaev; S Paavilainen; Timo Korpela
Characterization of bacterial growth on solid medium with image analysis.
Journal of biochemical and biophysical methods 1992;25(2-3):125-32.
1992: P Mattsson; Tiina Pohjalainen; Timo Korpela
Chemical modification of cyclomaltodextrin glucanotransferase from Bacillus circulans var. alkalophilus.
Biochimica et biophysica acta 1992;1122(1):33-40.
1990: P Mattsson; S Meklin; Timo Korpela
Analysis of cyclomaltodextrin glucanotransferase isoenzymes by isoelectric focusing in immobilized pH gradients.
Journal of biochemical and biophysical methods 1990;20(3):237-46.
1990: K Kurkijärvi; T Vierijoki; Timo Korpela
Flow-injection analysis of amino acids and their metabolites by immobilized vitamin B6-dependent enzymes. Sensitive determination of L-aspartate, L-glutamate, 2-oxoglutarate, and oxaloacetate.
Annals of the New York Academy of Sciences 1990;585():394-403.
1989: K Kurkijärvi; Timo Korpela
Immobilization of aspartate aminotransferase on agarose.
Biochimie 1989;71(4):439-48.
1988: M Mäkelä; A Elo; Timo Korpela
Acid-base chemistry of vitamin B6 compounds in methanol.
Journal of protein chemistry 1988;7(5):549-59.
1988: Mika J Mäkelä; Timo Korpela
Determination of the catalytic activity of cyclomaltodextrin glucanotransferase by maltotriose-methylorange assay.
Journal of biochemical and biophysical methods 1988;15(6):307-18.
1987: Timo Korpela; J Mattinen; Juha P Himanen; M L Mekhanic; Y M Torchinsky
Phosphorus-31 nuclear magnetic resonance of aspartate aminotransferase from chicken heart cytosol.
Biochimica et biophysica acta 1987;915(2):299-304.
1987: M Mäkelä; Timo Korpela; S Laakso
Colorimetric determination of beta-cyclodextrin: two assay modifications based on molecular complexation of phenolphtalein.
Journal of biochemical and biophysical methods 1987;14(2):85-92.
1984: Juha P Himanen; A Elo; Timo Korpela
Equilibria between vitamin B6-compounds and cyclodextrins.
Progress in clinical and biological research 1984;144A():109-14.
1983: K Kurkijärvi; Timo Korpela
Comparison of the coupling recoveries of immobilized aspartate aminotransferase. Specific activity, enzyme-bound coenzyme, and transaminationable active centers.
Applied biochemistry and biotechnology 1983;8(2):135-44.
1982: Timo Korpela; H Lorenz; S Laakso
A specific arginase-based assay for L-canavanine in leguminous plants.
Journal of biochemical and biophysical methods 1982;7(1):67-70.
1982: K Kurkijärvi; R Raunio; Timo Korpela
Packed-bed reactor of immobilized bacterial bioluminescence enzymes: a potential high-sensitivity detector for automated analyzers.
Analytical biochemistry 1982;125(2):415-9.
1981: Timo Korpela; Mika J Mäkelä
Spectrophotometric measurement of hydroxylamine and its O-alkyl derivatives.
Analytical biochemistry 1981;110(2):251-7.
1980: M Lehtokari; J Puisto; R Raunio; Timo Korpela
Spectrophotometric titrations of pyridoxal Schiff's bases in methanol using glass electrode for control of acidity.
Archives of biochemistry and biophysics 1980;202(2):533-9.
1980: Timo Korpela; K Kurkijärvi
A device for CNBr activation of agarose gels.
Analytical biochemistry 1980;104(1):150-2.