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Esa Korpi

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Bjørnar den Hollander; Anni-Maija Linden; Ilkka Ojanperä; Stanislav Rozov; Mikko Uusi-Oukari; Esa R Korpi
Long-term cognitive and neurochemical effects of "bath salt" designer drugs methylone and mephedrone.
Tommi Möykkynen; Esa R Korpi
Acute effects of ethanol on glutamate receptors.
Elena Vashchinkina; Olga Vekovischeva; Anne Panhelainen; Teemu Aitta-Aho; Nancy A Ator; Bjarke Ebert; Esa R Korpi
GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons.

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2013: Bjørnar den Hollander; Anni-Maija Linden; Ilkka Ojanperä; Stanislav Rozov; Mikko Uusi-Oukari; Esa R Korpi
Long-term cognitive and neurochemical effects of "bath salt" designer drugs methylone and mephedrone.
Pharmacology, biochemistry, and behavior 2013;103(3):501-9.
2012: Tommi Möykkynen; Esa R Korpi
Acute effects of ethanol on glutamate receptors.
Basic & clinical pharmacology & toxicology 2012;111(1):4-13.
2012: Elena Vashchinkina; Olga Vekovischeva; Anne Panhelainen; Teemu Aitta-Aho; Nancy A Ator; Bjarke Ebert; Esa R Korpi
GABA site agonist gaboxadol induces addiction-predicting persistent changes in ventral tegmental area dopamine neurons but is not rewarding in mice or baboons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2012;32(15):5310-20.
2012: Anne E Panhelainen; Esa R Korpi
Evidence for a role of inhibition of orexinergic neurons in the anxiolytic and sedative effects of diazepam: A c-Fos study.
Pharmacology, biochemistry, and behavior 2012;101(1):115-24.
2012: Artur Semenov; Sarah K Coleman; Esa R Korpi; Tommi Möykkynen; Kari Keinänen
Autoinactivation of the stargazin-AMPA receptor complex: subunit-dependency and independence from physical dissociation.
PloS one 2012;7(11):e49282.
2012: Teemu Aitta-Aho; Pia Bäckström; Tommi Möykkynen; Anne E Panhelainen; Olga Vekovischeva; Esa R Korpi
Importance of GluA1 subunit-containing AMPA glutamate receptors for morphine state-dependency.
PloS one 2012;7(5):e38325.
2011: A E Panhelainen; Ilpo Rasanen; Olga Vekovischeva; Teemu Aitta-Aho; Ilkka Ojanperä; Esa R Korpi
Diazepam-induced neuronal plasticity attenuates locomotor responses to morphine and amphetamine challenges in mice.
Neuroscience 2011;192():312-21.
2011: Elli Leppä; Anni-Maija Linden; Hartmut Lüddens; Holger Rabe; Olga Vekovischeva; william wisden; Peer Wulff; Esa R Korpi
Actions of two GABAA receptor benzodiazepine-site ligands that are mediated via non-γ2-dependent modulation.
European journal of pharmacology 2011;666(1-3):111-21.
2011: Nobuyoshi Tajima; Yutaka Itokazu; Esa R Korpi; Pentti Somerharju; Reijo Kakela
Activity of BK(Ca) channel is modulated by membrane cholesterol content and association with Na+/K+-ATPase in human melanoma IGR39 cells.
The Journal of biological chemistry 2011;286(7):5624-38.
2011: Zhe Jin; Olga Kononenko; Esa R Korpi; Georgy Bakalkin; Igor Bazov; Bryndis Birnir
Selective Changes of GABA(A) Channel Subunit mRNAs in the Hippocampus and Orbitofrontal Cortex but not in Prefrontal Cortex of Human Alcoholics.
Frontiers in cellular neuroscience 2011;5():30.
2011: Ulrich Tacke; Bjørnar den Hollander; Esa R Korpi; Katja Pihlainen; Kaarlo Simojoki; Hannu Alho
[Designer drugs in Finland].
Duodecim; lääketieteellinen aikakauskirja 2011;127(19):2027-36.
2011: Elli Leppä; Anni-Maija Linden; Ville Rantanen; Werner Sieghart; Jerome D Swinny; Esko Toppila; Olga Vekovischeva; william wisden; Peer Wulff; Harald Höger; Esa R Korpi
Removal of GABA(A) receptor γ2 subunits from parvalbumin neurons causes wide-ranging behavioral alterations.
PloS one 2011;6(9):e24159.
2011: Anni-Maija Linden; Ulrich Schmitt; Elli Leppä; Peer Wulff; william wisden; Hartmut Lüddens; Esa R Korpi
Ro 15-4513 Antagonizes Alcohol-Induced Sedation in Mice Through αβγ2-type GABA(A) Receptors.
Frontiers in neuroscience 2011;5():3.
2011: Chiara Procaccini; Teemu Aitta-Aho; Külli Jaako-Movits; Alexander Zharkovsky; Anne Panhelainen; Rolf Sprengel; Anni-Maija Linden; Esa R Korpi
Excessive novelty-induced c-Fos expression and altered neurogenesis in the hippocampus of GluA1 knockout mice.
The European journal of neuroscience 2011;33(1):161-74.
2010: Sarah K Coleman; Tommi Möykkynen; Sami Hinkkuri; Lauri Vaahtera; Esa R Korpi; Olli Pentikäinen; Kari Keinänen
Ligand-binding domain determines endoplasmic reticulum exit of AMPA receptors.
The Journal of biological chemistry 2010;285(46):36032-9.
2010: Y Lyubimov; M Engstrom; S Wurster; Juha-Matti Savola; Esa R Korpi; Pertti Panula
Human kisspeptins activate neuropeptide FF2 receptor.
Neuroscience 2010;170(1):117-22.
2010: Kati S Hellsten; Saku T Sinkkonen; Thomas M Hyde; Joel E Kleinman; Terttu Särkioja; Anu Maksimow; Mikko Uusi-Oukari; Esa R Korpi
Human locus coeruleus neurons express the GABA(A) receptor gamma2 subunit gene and produce benzodiazepine binding.
Neuroscience letters 2010;477(2):77-81.
2010: Mikko Uusi-Oukari; Esa R Korpi
Regulation of GABA(A) receptor subunit expression by pharmacological agents.
Pharmacological reviews 2010;62(1):97-135.
2010: Dev Chandra; Lauri M Halonen; Anni-Maija Linden; Chiara Procaccini; Kati Hellsten; Gregg E Homanics; Esa R Korpi
Prototypic GABA(A) receptor agonist muscimol acts preferentially through forebrain high-affinity binding sites.
Neuropsychopharmacology : official publication of the American College of Neuropsychopharmacology 2010;35(4):999-1007.
2010: Sarah K Coleman; Chunlin Cai; Nisse Kalkkinen; Esa R Korpi; Kari Keinänen
Analysis of the potential role of GluA4 carboxyl-terminus in PDZ interactions.
PloS one 2010;5(1):e8715.
2010: Saara Nuutinen; Kaj Karlstedt; Teemu Aitta-Aho; Esa R Korpi; Pertti Panula
Histamine and H3 receptor-dependent mechanisms regulate ethanol stimulation and conditioned place preference in mice.
Psychopharmacology 2010;208(1):75-86.
2009: Lauri M Halonen; Saku T Sinkkonen; Dev Chandra; Gregg E Homanics; Esa R Korpi
Brain regional distribution of GABA(A) receptors exhibiting atypical GABA agonism: roles of receptor subunits.
Neurochemistry international 2009;55(6):389-96.
2009: Ivan Marinkovic; Daniel Strbian; Eric Pedrono; Olga Y Vekovischeva; Shashank Shekhar; Aysan Durukan; Esa R Korpi; Usama Abo Ramadan; Turgut Tatlisumak
Decompressive craniectomy for intracerebral hemorrhage.
Neurosurgery 2009;65(4):780-6, 1 p following 786; discussion 786.
2009: Anni-Maija Linden; B G Johnson; Nina Trokovic; Esa R Korpi; D D Schoepp
Use of MGLUR2 and MGLUR3 knockout mice to explore in vivo receptor specificity of the MGLUR2/3 selective antagonist LY341495.
Neuropharmacology 2009;57(2):172-82.
2009: Tommi Möykkynen; Sarah K Coleman; Kari Keinänen; David M Lovinger; Esa R Korpi
Ethanol increases desensitization of recombinant GluR-D AMPA receptor and TARP combinations.
Alcohol (Fayetteville, N.Y.) 2009;43(4):277-84.
2009: Teemu Aitta-Aho; Olga Vekovischeva; Pertti J Neuvonen; Esa R Korpi
Reduced benzodiazepine tolerance, but increased flumazenil-precipitated withdrawal in AMPA-receptor GluR-A subunit-deficient mice.
Pharmacology, biochemistry, and behavior 2009;92(2):283-90.
2009: Sarah K Coleman; Tommi Möykkynen; Annukka Jouppila; Susanna Koskelainen; Claudio Rivera; Esa R Korpi; Kari Keinänen
Agonist occupancy is essential for forward trafficking of AMPA receptors.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(2):303-12.
2008: Anni-Maija Linden; M Isabel Aller; Elli Leppä; Per H Rosenberg; william wisden; Esa R Korpi
K+ channel TASK-1 knockout mice show enhanced sensitivities to ataxic and hypnotic effects of GABA(A) receptor ligands.
The Journal of pharmacology and experimental therapeutics 2008;327(1):277-86.
2008: Tanja Vihavainen; Marjo Piltonen; Raimo K Tuominen; Esa R Korpi; Liisa Ahtee
Morphine-nicotine interaction in conditioned place preference in mice after chronic nicotine exposure.
European journal of pharmacology 2008;587(1-3):169-74.
2008: Kati S Saarelainen; Martin Ranna; Holger Rabe; Saku T Sinkkonen; Tommi Möykkynen; Mikko Uusi-Oukari; Anni-Maija Linden; Hartmut Lüddens; Esa R Korpi
Enhanced behavioral sensitivity to the competitive GABA agonist, gaboxadol, in transgenic mice over-expressing hippocampal extrasynaptic alpha6beta GABA(A) receptors.
Journal of neurochemistry 2008;105(2):338-50.
2008: Elina Salmi; Ruut M Laitio; Sargo Aalto; Anu Maksimow; Jaakko W Långsjö; Kaike K Kaisti; Riku Aantaa; Vesa Oikonen; Liisa Metsähonkala; Kjell Någren; Esa R Korpi; Harry Scheinin
Xenon does not affect gamma-aminobutyric acid type A receptor binding in humans.
Anesthesia and analgesia 2008;106(1):129-34, table of contents.
2007: Anni-Maija Linden; Cristina Sandu; M Isabel Aller; Olga Vekovischeva; Per H Rosenberg; william wisden; Esa R Korpi
TASK-3 knockout mice exhibit exaggerated nocturnal activity, impairments in cognitive functions, and reduced sensitivity to inhalation anesthetics.
The Journal of pharmacology and experimental therapeutics 2007;323(3):924-34.
2007: Peer Wulff; Thomas Goetz; Elli Leppä; Anni-Maija Linden; Massimiliano Renzi; Jerome D Swinny; Olga Vekovischeva; Werner Sieghart; Peter Somogyi; Esa R Korpi; Mark Farrant; william wisden
From synapse to behavior: rapid modulation of defined neuronal types with engineered GABAA receptors.
Nature neuroscience 2007;10(7):923-9.
2007: Olga Vekovischeva; Teemu Aitta-Aho; Elena Verbitskaya; K Sandnabba; Esa R Korpi
Acute effects of AMPA-type glutamate receptor antagonists on intermale social behavior in two mouse lines bidirectionally selected for offensive aggression.
Pharmacology, biochemistry, and behavior 2007;87(2):241-9.
2007: Esa R Korpi; Fabian Debus; Anni-Maija Linden; Cécile Malécot; Elli Leppä; Olga Vekovischeva; Holger Rabe; Ingo Böhme; M Isabel Aller; william wisden; Hartmut Lüddens
Does ethanol act preferentially via selected brain GABAA receptor subtypes? the current evidence is ambiguous.
Alcohol (Fayetteville, N.Y.) 2007;41(3):163-76.
2007: Olga Vekovischeva; Elena Verbitskaya; Teemu Aitta-Aho; K Sandnabba; Esa R Korpi
Multimetric statistical analysis of behavior in mice selected for high and low levels of isolation-induced male aggression.
Behavioural processes 2007;75(1):23-32.
2007: Tommi Möykkynen; Saku T Sinkkonen; Esa R Korpi
Compensation by reduced L-alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor responses in a mouse model with reduced gamma-aminobutyric acid type A receptor-mediated synaptic inhibition.
Journal of neuroscience research 2007;85(3):668-72.
2007: Bryndis Birnir; Esa R Korpi
The impact of sub-cellular location and intracellular neuronal proteins on properties of GABA(A) receptors.
Current pharmaceutical design 2007;13(31):3169-77.
2006: Maija Sarviharju; Petri Hyytiä; Antti Hervonen; Pia Jaatinen; Kalervo Kiianmaa; Esa R Korpi
Lifelong ethanol consumption and brain regional GABAA receptor subunit mRNA expression in alcohol-preferring rats.
Alcohol (Fayetteville, N.Y.) 2006;40(3):159-66.
2006: Sarah K Coleman; Tommi Möykkynen; Chunlin Cai; Lotta von Ossowski; Esa Kuismanen; Esa R Korpi; Kari Keinänen
Isoform-specific early trafficking of AMPA receptor flip and flop variants.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(43):11220-9.
2006: Kim Lemberg; Vesa K Kontinen; Antti O Siiskonen; Kaarin M Viljakka; Jari Yli-Kauhaluoma; Esa R Korpi; Eija Kalso
Antinociception by spinal and systemic oxycodone: why does the route make a difference? In vitro and in vivo studies in rats.
Anesthesiology 2006;105(4):801-12.
2006: Kimmo Ingman; Johanna Kupila; Petri Hyytiä; Esa R Korpi
Effects of aripiprazole on alcohol intake in an animal model of high-alcohol drinking.
Alcohol and alcoholism (Oxford, Oxfordshire) 2006;41(4):391-8.
2006: Virpi Salonen; Sampsa Kallinen; Francisco R Lopez-Picon; Esa R Korpi; Irma E Holopainen; Mikko Uusi-Oukari
AMPA/kainate receptor-mediated up-regulation of GABAA receptor delta subunit mRNA expression in cultured rat cerebellar granule cells is dependent on NMDA receptor activation.
Brain research 2006;1087(1):33-40.
2006: Anni-Maija Linden; M Isabel Aller; Elli Leppä; Olga Vekovischeva; Teemu Aitta-Aho; Emma L Veale; Alistair Mathie; Per Rosenberg; william wisden; Esa R Korpi
The in vivo contributions of TASK-1-containing channels to the actions of inhalation anesthetics, the alpha(2) adrenergic sedative dexmedetomidine, and cannabinoid agonists.
The Journal of pharmacology and experimental therapeutics 2006;317(2):615-26.
2006: Kimmo Ingman; Esa R Korpi
Alcohol drinking of alcohol-preferring AA rats is differentially affected by clozapine and olanzapine.
European journal of pharmacology 2006;534(1-3):133-40.
2006: Esa R Korpi
[Not Available].
Duodecim; lääketieteellinen aikakauskirja 2006;122(21):2559-61.
2006: Martin Ranna; Saku T Sinkkonen; Tommi Möykkynen; Mikko Uusi-Oukari; Esa R Korpi
Impact of epsilon and theta subunits on pharmacological properties of alpha3beta1 GABAA receptors expressed in Xenopus oocytes.
BMC pharmacology 2006;6():1.
2006: Esa R Korpi; Saku T Sinkkonen
GABA(A) receptor subtypes as targets for neuropsychiatric drug development.
Pharmacology & therapeutics 2006;109(1-2):12-32.
2005: M Isabel Aller; Emma L Veale; Anni-Maija Linden; Cristina Sandu; Markus Schwaninger; Louisa J Evans; Esa R Korpi; Alistair Mathie; william wisden; Stephen G Brickley
Modifying the subunit composition of TASK channels alters the modulation of a leak conductance in cerebellar granule neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2005;25(49):11455-67.
2005: Saku T Sinkkonen; Holger Rabe; Hartmut Lüddens; Esa R Korpi
Evidence for a reduction of coupling between GABAA receptor agonist and ionophore binding sites by inorganic phosphate.
Neurochemical research 2005;30(12):1471-82.
2005: Herminia Pasantes-Morales; Esa R Korpi
Simo S. Oja--amino acids all along as building blocks of brain and life.
Neurochemical research 2005;30(12):1463-4.
2005: Tommi Möykkynen; Ron Liebkind; Jari Sjöberg; Esa R Korpi; Päivi Liesi
The neuroprotective KDI domain of gamma 1-laminin is a universal and potent inhibitor of ionotropic glutamate receptors.
Journal of neuroscience research 2005;81(6):797-804.
2005: Elina Salmi; Jaakko W Långsjö; Sargo Aalto; Kjell Någren; Liisa Metsähonkala; Kaike K Kaisti; Esa R Korpi; Jarmo Hietala; Harry Scheinin
Subanesthetic ketamine does not affect 11C-flumazenil binding in humans.
Anesthesia and analgesia 2005;101(3):722-5, table of contents.
2005: Jukka S Pakkanen; Heli Nousiainen; Jari Yli-Kauhaluoma; Irene Kylänlahti; Tommi Möykkynen; Esa R Korpi; Jian-Hong Peng; Ronald J. Lukas; Liisa Ahtee; Raimo K Tuominen
Methadone increases intracellular calcium in SH-SY5Y and SH-EP1-halpha7 cells by activating neuronal nicotinic acetylcholine receptors.
Journal of neurochemistry 2005;94(5):1329-41.
2005: Hanna B Laurén; Francisco R Lopez-Picon; Esa R Korpi; Irma E Holopainen
Kainic acid-induced status epilepticus alters GABA receptor subunit mRNA and protein expression in the developing rat hippocampus.
Journal of neurochemistry 2005;94(5):1384-94.
2005: Juuso Juhila; Aapo Honkanen; Jukka Sallinen; Antti Haapalinna; Esa R Korpi; Mika Scheinin
alpha(2A)-Adrenoceptors regulate d-amphetamine-induced hyperactivity and behavioural sensitization in mice.
European journal of pharmacology 2005;517(1-2):74-83.
2005: James M Sonner; Mike Cascio; Yilei Xing; Michael S Fanselow; Jason E Kralic; A Leslie Morrow; Esa R Korpi; Steven Hardy; Brian Sloat; Edmond I Eger; Gregg E Homanics
Alpha 1 subunit-containing GABA type A receptors in forebrain contribute to the effect of inhaled anesthetics on conditioned fear.
Molecular pharmacology 2005;68(1):61-8.
2005: David Cope; C Halbsguth; Theofanis Karayannis; Peer Wulff; Francesco Ferraguti; H Hoeger; Elli Leppä; Anni-Maija Linden; Alessandra Oberto; Waltraud Ogris; Esa R Korpi; Werner Sieghart; Peter Somogyi; william wisden; Marco Capogna
Loss of zolpidem efficacy in the hippocampus of mice with the GABAA receptor gamma2 F77I point mutation.
The European journal of neuroscience 2005;21(11):3002-16.
2005: Elli Leppä; Olga Vekovischeva; A-M Lindén; Peer Wulff; Alessandra Oberto; william wisden; Esa R Korpi
Agonistic effects of the beta-carboline DMCM revealed in GABA(A) receptor gamma 2 subunit F77I point-mutated mice.
Neuropharmacology 2005;48(4):469-78.
2005: Markus M Lindroos; Sanna L Soini; Tiina-Kaisa Kukko-Lukjanov; Esa R Korpi; David M Lovinger; Irma E Holopainen
Maturation of cultured hippocampal slices results in increased excitability in granule cells.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2005;23(1):65-73.
2005: Antti Pertovaara; Maria Ostergård; Minna-Liisa Ankö; S Lehti-Koivunen; A Brandt; W Hong; Esa R Korpi; Pertti Panula
RFamide-related peptides signal through the neuropeptide FF receptor and regulate pain-related responses in the rat.
Neuroscience 2005;134(3):1023-32.
2005: Dev Chandra; Esa R Korpi; Celia P Miralles; Angel L De Blas; Gregg E Homanics
GABAA receptor gamma 2 subunit knockdown mice have enhanced anxiety-like behavior but unaltered hypnotic response to benzodiazepines.
BMC neuroscience 2005;6():30.
2004: Elina Salmi; Kaike K Kaisti; Liisa Metsähonkala; Vesa Oikonen; Sargo Aalto; Kjell Någren; Susanna Hinkka; Jarmo Hietala; Esa R Korpi; Harry Scheinin
Sevoflurane and propofol increase 11C-flumazenil binding to gamma-aminobutyric acidA receptors in humans.
Anesthesia and analgesia 2004;99(5):1420-6; table of contents.
2004: Saku T Sinkkonen; Olga Vekovischeva; Tommi Möykkynen; Waltraud Ogris; Werner Sieghart; william wisden; Esa R Korpi
Behavioural correlates of an altered balance between synaptic and extrasynaptic GABAAergic inhibition in a mouse model.
The European journal of neuroscience 2004;20(8):2168-78.
2004: Olga Vekovischeva; Teemu Aitta-Aho; O Echenko; Aino Kankaanpää; Timo Seppälä; Aapo Honkanen; Rolf Sprengel; Esa R Korpi
Reduced aggression in AMPA-type glutamate receptor GluR-A subunit-deficient mice.
Genes, brain, and behavior 2004;3(5):253-65.
2004: Saku T Sinkkonen; Anni-Maija Lindén; Esa R Korpi; Garry Wong
Selective reduction of gamma-aminobutyric acid type A receptor delta subunit mRNA levels by MK-801 in rat dentate gyrus.
Neuroscience letters 2004;364(2):106-9.
2004: David Cope; Peer Wulff; Alessandra Oberto; M I Aller; Marco Capogna; Francesco Ferraguti; C Halbsguth; H Hoeger; Helen E Jolin; Alison Jones; Andrew N J McKenzie; Waltraud Ogris; A Poeltl; Saku T Sinkkonen; Olga Vekovischeva; Esa R Korpi; Werner Sieghart; Erwin Sigel; Peter Somogyi; william wisden
Abolition of zolpidem sensitivity in mice with a point mutation in the GABAA receptor gamma2 subunit.
Neuropharmacology 2004;47(1):17-34.
2004: Saku T Sinkkonen; Bernhard Lüscher; Hartmut Lüddens; Esa R Korpi
Autoradiographic imaging of altered synaptic alphabetagamma2 and extrasynaptic alphabeta GABAA receptors in a genetic mouse model of anxiety.
Neurochemistry international 2004;44(7):539-47.
2004: Kimmo Ingman; Jukka Sallinen; Aapo Honkanen; Esa R Korpi
Comparison of deramciclane to benzodiazepine agonists in behavioural activity of mice and in alcohol drinking of alcohol-preferring rats.
Pharmacology, biochemistry, and behavior 2004;77(4):847-54.
2004: Mikko Uusi-Oukari; Paula Kosonen; Gregg E Homanics; Esa R Korpi
Brain regional heterogeneity of pH effects on GABA(A) receptor-associated [35s]TBPS binding.
Neurochemical research 2004;29(4):771-80.
2004: Ilkka K Martikainen; Kadri Lauk; Tommi Möykkynen; Irma E Holopainen; Esa R Korpi; Mikko Uusi-Oukari
Kainate down-regulates a subset of GABAA receptor subunits expressed in cultured mouse cerebellar granule cells.
Cerebellum (London, England) 2004;3(1):27-38.
2003: Hanna B Laurén; Asla Pitkänen; Jari Nissinen; Sanna L Soini; Esa R Korpi; Irma E Holopainen
Selective changes in gamma-aminobutyric acid type A receptor subunits in the hippocampus in spontaneously seizing rats with chronic temporal lobe epilepsy.
Neuroscience letters 2003;349(1):58-62.
2003: Saku T Sinkkonen; Salla Mansikkamäki; Tommi Möykkynen; Hartmut Lüddens; Mikko Uusi-Oukari; Esa R Korpi
Receptor subtype-dependent positive and negative modulation of GABA(A) receptor function by niflumic acid, a nonsteroidal anti-inflammatory drug.
Molecular pharmacology 2003;64(3):753-63.
2003: Tommi Möykkynen; Esa R Korpi; David M Lovinger
Ethanol inhibits alpha-amino-3-hydyroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptor function in central nervous system neurons by stabilizing desensitization.
The Journal of pharmacology and experimental therapeutics 2003;306(2):546-55.
2003: Kimmo Ingman; Severo Salvadori; Larry Lazarus; Esa R Korpi; Aapo Honkanen
Selective delta-opioid receptor antagonist N,N(CH3)2-Dmt-Tic-OH does not reduce ethanol intake in alcohol-preferring AA rats.
Addiction biology 2003;8(2):173-9.
2003: Kimmo Ingman; Aapo Honkanen; Petri Hyytiä; Matti O Huttunen; Esa R Korpi
Risperidone reduces limited access alcohol drinking in alcohol-preferring rats.
European journal of pharmacology 2003;468(2):121-7.
2003: Olga Vekovischeva; Mikko Uusi-Oukari; Esa R Korpi
Tolerance to diazepam-induced motor impairment: a study with GABAA receptor alpha6 subunit knockout mice.
Neurochemical research 2003;28(5):757-64.
2003: Saku T Sinkkonen; Gregg E Homanics; Esa R Korpi
Mouse models of Angelman syndrome, a neurodevelopmental disorder, display different brain regional GABA(A) receptor alterations.
Neuroscience letters 2003;340(3):205-8.
2003: Juuso Juhila; Antti Haapalinna; Jouni Sirviö; Jukka Sallinen; Aapo Honkanen; Esa R Korpi; Mika Scheinin
The alpha2-adrenoceptor antagonist atipamezole reduces the development and expression of d-amphetamine-induced behavioural sensitization.
Naunyn-Schmiedeberg's archives of pharmacology 2003;367(3):274-80.
2003: Esa R Korpi; Perttu J Lindsberg
[New challenges of brain research].
Duodecim; lääketieteellinen aikakauskirja 2003;119(15):1461-3.
2002: william wisden; David Cope; Thomas Klausberger; B Hauer; Saku T Sinkkonen; Verena Tretter; R Lujan; Alison Jones; Esa R Korpi; I Mody; Werner Sieghart; Peter Somogyi
Ectopic expression of the GABA(A) receptor alpha6 subunit in hippocampal pyramidal neurons produces extrasynaptic receptors and an increased tonic inhibition.
Neuropharmacology 2002;43(4):530-49.
2002: Kristina Raatesalmi; Antti Virtanen; Maija Sarviharju; Markku Pelto-Huikko And; Esa R Korpi
Reduced adrenal activation in a rat line selected for high alcohol sensitivity.
Alcoholism, clinical and experimental research 2002;26(9):1344-9.
2002: Jason E Kralic; Esa R Korpi; Todd O'Buckley; Gregg E Homanics; A Leslie Morrow
Molecular and pharmacological characterization of GABA(A) receptor alpha1 subunit knockout mice.
The Journal of pharmacology and experimental therapeutics 2002;302(3):1037-45.
2002: Sanna L Soini; Petri Hyytiä; Esa R Korpi
Brain regional mu-opioid receptor function in rat lines selected for differences in alcohol preference.
European journal of pharmacology 2002;448(2-3):157-63.
2002: Esa R Korpi; Gerhard Gründer; Hartmut Lüddens
Drug interactions at GABA(A) receptors.
Progress in neurobiology 2002;67(2):113-59.
2002: Minnamaija Lintunen; Kristiina Raatesalmi; Tina Sallmen; Oleg V Anichtchik; Kaj Karlstedt; Jan Kaslin; Kalervo Kiianmaa; Esa R Korpi; Pertti Panula
Low brain histamine content affects ethanol-induced motor impairment.
Neurobiology of disease 2002;9(1):94-105.
2002: Esa R Korpi; Robert M Mihalek; Saku T Sinkkonen; Birgit Hauer; Wulf Hevers; Gregg E Homanics; Werner Sieghart; Hartmut Lüddens
Altered receptor subtypes in the forebrain of GABA(A) receptor delta subunit-deficient mice: recruitment of gamma 2 subunits.
Neuroscience 2002;109(4):733-43.
2001: Mikko Uusi-Oukari; Rauno Mäkelä; Sanna L Soini; Esa R Korpi
Cation modulation of GABA(A) receptors in brain sections of AT and ANT rats.
Alcohol (Fayetteville, N.Y.) 2001;25(2):69-75.
2001: A T Heikkilä; O Echenko; Mikko Uusi-Oukari; Saku T Sinkkonen; Esa R Korpi
Morphine withdrawal increases expression of GABA(A) receptor epsilon subunit mRNA in locus coeruleus neurons.
Neuroreport 2001;12(13):2981-5.
2001: Tommi Möykkynen; Mikko Uusi-Oukari; J Heikkilä; David M Lovinger; Hartmut Lüddens; Esa R Korpi
Magnesium potentiation of the function of native and recombinant GABA(A) receptors.
Neuroreport 2001;12(10):2175-9.
2001: Olga Vekovischeva; D Zamanillo; O Echenko; Timo Seppälä; Mikko Uusi-Oukari; Aapo Honkanen; Peter H Seeburg; Rolf Sprengel; Esa R Korpi
Morphine-induced dependence and sensitization are altered in mice deficient in AMPA-type glutamate receptor-A subunits.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(12):4451-9.
2001: Esa R Korpi; Rauno Mäkelä; Elena Romeo; Alessandro Guidotti; Mikko Uusi-Oukari; C Furnari; Flavia di Michele; Maija Sarviharju; M Xu; P H Rosenberg
Increased behavioral neurosteroid sensitivity in a rat line selectively bred for high alcohol sensitivity.
European journal of pharmacology 2001;421(1):31-8.
2001: Minnamaija Lintunen; Petri Hyytiä; Tina Sallmen; Kaj Karlstedt; Leena Tuomisto; Rob Leurs; Kalervo Kiianmaa; Esa R Korpi; Pertti Panula
Increased brain histamine in an alcohol-preferring rat line and modulation of ethanol consumption by H(3) receptor mechanisms.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(6):1074-6.
2001: Saku T Sinkkonen; Robert M Mihalek; Gregg E Homanics; Hartmut Lüddens; Esa R Korpi
Altered atypical coupling of gamma-aminobutyrate type A receptor agonist and convulsant binding sites in subunit-deficient mouse lines.
Brain research. Molecular brain research 2001;86(1-2):179-83.
2001: Saku T Sinkkonen; Mikko Uusi-Oukari; Erkki Tupala; Terttu Särkioja; J Tiihonen; Pertti Panula; Hartmut Lüddens; Esa R Korpi
Characterization of gamma-aminobutyrate type A receptors with atypical coupling between agonist and convulsant binding sites in discrete brain regions.
Brain research. Molecular brain research 2001;86(1-2):168-78.
2001: Irma E Holopainen; H Kokkonen; Esa R Korpi
[Angelman syndrome--from the phenotype of a developmental disorder to the genes].
Duodecim; lääketieteellinen aikakauskirja 2001;117(4):383-7.
2001: Irma E Holopainen; Riikka Kivelä; Esa R Korpi
Do antiepileptics phenytoin, carbamazepine, and loreclezole show GABA(A) receptor subtype selectivity in rat brain sections?
Neurochemical research 2001;26(1):89-94.
2001: Irma E Holopainen; E L Metsähonkala; H Kokkonen; Riitta Parkkola; Tuula Manner; K Någren; Esa R Korpi
Decreased binding of [11C]flumazenil in Angelman syndrome patients with GABA(A) receptor beta3 subunit deletions.
Annals of neurology 2001;49(1):110-3.
2000: Wulf Hevers; Esa R Korpi; Hartmut Lüddens
Assembly of functional alpha6beta3gamma2delta GABA(A) receptors in vitro.
Neuroreport 2000;11(18):4103-6.
2000: Holger Rabe; R Picard; Mikko Uusi-Oukari; Wulf Hevers; Hartmut Lüddens; Esa R Korpi
Coupling between agonist and chloride ionophore sites of the GABA(A) receptor: agonist/antagonist efficacy of 4-PIOL.
European journal of pharmacology 2000;409(3):233-42.
2000: Olga Vekovischeva; Antti Haapalinna; R Näkki; Maija Sarviharju; Aapo Honkanen; J Heikkilä; Esa R Korpi
Enhanced locomotor stimulation by NMDA receptor antagonists in alcohol-sensitive ANT rats.
Pharmacology, biochemistry, and behavior 2000;67(4):793-9.
2000: Leonard L Firestone; Esa R Korpi; L Niemi; Per H Rosenberg; Gregg E Homanics; Joseph J Quinlan
Halothane and desflurane requirements in alcohol-tolerant and -nontolerant rats.
British journal of anaesthesia 2000;85(5):757-62.
2000: Olga Vekovischeva; Mikko Uusi-Oukari; Esa R Korpi
Chronic ethanol treatment and GABA(A) receptor α6 subunit gene expression: a study using α6 subunit-deficient mice.
Addiction biology 2000;5(4):463-7.
2000: Irina Podkletnova; Hannu Alho; Rauno Mäkelä; Hartmut Lüddens; P Helén; Esa R Korpi
Neonatal 6-hydroxydopamine treatment affects GABA(A) receptor subunit expression during postnatal development of the rat cerebellum.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 2000;18(6):565-72.
2000: Mikko Uusi-Oukari; Sanna L Soini; J Heikkilä; A Koivisto; Kari Neuvonen; Paavo Pasanen; Saku T Sinkkonen; Jarmo Laihia; Christer T Jansén; Esa R Korpi
Stereospecific modulation of GABA(A) receptor function by urocanic acid isomers.
European journal of pharmacology 2000;400(1):11-7.
2000: Mikko Uusi-Oukari; J Heikkilä; Saku T Sinkkonen; Rauno Mäkelä; Birgit Hauer; Gregg E Homanics; Werner Sieghart; william wisden; Esa R Korpi
Long-range interactions in neuronal gene expression: evidence from gene targeting in the GABA(A) receptor beta2-alpha6-alpha1-gamma2 subunit gene cluster.
Molecular and cellular neurosciences 2000;16(1):34-41.
2000: Saku T Sinkkonen; MC Hanna; E F Kirkness; Esa R Korpi
GABA(A) receptor epsilon and theta subunits display unusual structural variation between species and are enriched in the rat locus ceruleus.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(10):3588-95.
2000: Mikko Uusi-Oukari; R Kleinz; Rauno Mäkelä; Hartmut Lüddens; Esa R Korpi
Quantification of GABA(A) receptor subunit mRNAs by non-radioisotopic competitive RT-PCR utilizing plate-based EIA methodology.
Journal of neuroscience methods 2000;95(1):65-73.
2000: Irina Podkletnova; Rauno Mäkelä; Esa R Korpi; Hartmut Lüddens; P Helen; Hannu Alho
Neonatal 6-hydroxydopamine treatment affects GABA(A) receptor subunit expression in the frontal cortex but not the hippocampus of rats during postnatal development.
Developmental neuroscience 2000;22(4):296-302.
1999: Rauno Mäkelä; Mikko Uusi-Oukari; S S Oja; Hannu Alho; Ion Anghelescu; Christoph Klawe; Hartmut Lüddens; Esa R Korpi
Furosemide action on cerebellar GABA(A) receptors in alcohol-sensitive ANT rats.
Alcohol (Fayetteville, N.Y.) 1999;19(3):197-205.
1999: Robert M Mihalek; P K Banerjee; Esa R Korpi; Joseph J Quinlan; Leonard L Firestone; ZP Mi; Carl F Lagenaur; Verena Tretter; Werner Sieghart; Stephan Anagnostaras; J R Sage; Michael S Fanselow; Alessandro Guidotti; Igor Spigelman; Z Li; Timothy M DeLorey; Richard W Olsen; Gregg E Homanics
Attenuated sensitivity to neuroactive steroids in gamma-aminobutyrate type A receptor delta subunit knockout mice.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(22):12905-10.
1999: Petri Hyytiä; Kimmo Ingman; Sanna L Soini; J T Laitinen; Esa R Korpi
Effects of continuous opioid receptor blockade on alcohol intake and up-regulation of opioid receptor subtype signalling in a genetic model of high alcohol drinking.
Naunyn-Schmiedeberg's archives of pharmacology 1999;360(4):391-401.
1999: G Schmid; Giambattista Bonanno; Luca Raiteri; Maija Sarviharju; Esa R Korpi; Maurizio Raiteri
Enhanced benzodiazepine and ethanol actions on cerebellar GABA(A) receptors mediating glutamate release in an alcohol-sensitive rat line.
Neuropharmacology 1999;38(9):1273-9.
1999: Olga Vekovischeva; Antti Haapalinna; Maija Sarviharju; Aapo Honkanen; Esa R Korpi
Cerebellar GABA(A) receptors and anxiolytic action of diazepam.
Brain research 1999;837(1-2):184-7.
1999: Sanna L Soini; Aapo Honkanen; Petri Hyytiä; Esa R Korpi
[3H]ethylketocyclazocine binding to brain opioid receptor subtypes in alcohol-preferring AA and alcohol-avoiding ANA rats.
Alcohol (Fayetteville, N.Y.) 1999;18(1):27-34.
1999: Aapo Honkanen; Petri Hyytiä; Esa R Korpi; Liisa Ahtee
Effects of morphine on metabolism of dopamine and serotonin in brains of alcohol-preferring AA and alcohol-avoiding ANA rats.
Alcohol (Fayetteville, N.Y.) 1999;18(1):3-10.
1999: Aapo Honkanen; Janne A V Mikkola; Esa R Korpi; Petri Hyytiä; Timo Seppälä; Liisa Ahtee
Enhanced morphine- and cocaine-induced behavioral sensitization in alcohol-preferring AA rats.
Psychopharmacology 1999;142(3):244-52.
1999: Rauno Mäkelä; william wisden; Esa R Korpi
Loreclezole and La3+ differentiate cerebellar granule cell GABA(A) receptor subtypes.
European journal of pharmacology 1999;367(1):101-5.
1999: Esa R Korpi; P Koikkalainen; Olga Vekovischeva; Rauno Mäkelä; R Kleinz; Mikko Uusi-Oukari; william wisden
Cerebellar granule-cell-specific GABAA receptors attenuate benzodiazepine-induced ataxia: evidence from alpha 6-subunit-deficient mice.
The European journal of neuroscience 1999;11(1):233-40.
1998: C Jackel; R Kleinz; Rauno Mäkelä; Wulf Hevers; S Jezequel; Esa R Korpi; Hartmut Lüddens
The main determinant of furosemide inhibition on GABA(A) receptors is located close to the first transmembrane domain.
European journal of pharmacology 1998;357(2-3):251-6.
1998: Sanna L Soini; T Ovaska; Aapo Honkanen; Petri Hyytiä; Esa R Korpi
Brain opioid receptor binding of [3H]CTOP and [3H]naltrindole in alcohol-preferring AA and alcohol-avoiding ANA rats.
Alcohol (Fayetteville, N.Y.) 1998;15(3):227-32.
1998: Hartmut Lüddens; H J Lang; Esa R Korpi
Structure-activity relationship of furosemide-derived compounds as antagonists of cerebellum-specific GABA(A) receptors.
European journal of pharmacology 1998;344(2-3):269-77.
1998: Esa R Korpi; Timo Seppälä
[Alcohol--mechanism of action, interactions and treatment of alcohol abuse].
Duodecim; lääketieteellinen aikakauskirja 1998;114(10):1029-36.
1997: Aapo Honkanen; Liisa Ahtee; Esa R Korpi
Voluntary alcohol drinking selectively accelerates dopamine release in the ventral striatum as reflected by 3-methoxytyramine levels.
Brain research 1997;774(1-2):207-10.
1997: Rauno Mäkelä; Mikko Uusi-Oukari; Gregg E Homanics; Joseph J Quinlan; Leonard L Firestone; william wisden; Esa R Korpi
Cerebellar gamma-aminobutyric acid type A receptors: pharmacological subtypes revealed by mutant mouse lines.
Molecular pharmacology 1997;52(3):380-8.
1997: Esa R Korpi; M J Mattila; william wisden; Hartmut Lüddens
GABA(A)-receptor subtypes: clinical efficacy and selectivity of benzodiazepine site ligands.
Annals of medicine 1997;29(4):275-82.
1997: M Toropainen; R Näkki; Aapo Honkanen; P H Rosenberg; D J Laurie; M Pelto-Huikko; J Koistinaho; C J Eriksson; Esa R Korpi
Behavioral sensitivity and ethanol potentiation of the N-methyl-D-aspartate receptor antagonist MK-801 in a rat line selected for high ethanol sensitivity.
Alcoholism, clinical and experimental research 1997;21(4):666-71.
1997: Gregg E Homanics; Timothy M DeLorey; Leonard L Firestone; Joseph J Quinlan; Adrian Handforth; Neil L Harrison; Matthew D Krasowski; CE Rick; Esa R Korpi; Rauno Mäkelä; M H Brilliant; N Hagiwara; Carolyn Ferguson; K Snyder; Richard W Olsen
Mice devoid of gamma-aminobutyrate type A receptor beta3 subunit have epilepsy, cleft palate, and hypersensitive behavior.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(8):4143-8.
1997: Esa R Korpi; Hartmut Lüddens
Furosemide interactions with brain GABAA receptors.
British journal of pharmacology 1997;120(5):741-8.
1997: Alison Jones; Esa R Korpi; R M McKernan; R Pelz; Zoltan Nusser; Rauno Mäkelä; J R Mellor; Simon Pollard; S Bahn; F Anne Stephenson; Andrew D Randall; Werner Sieghart; Peter Somogyi; A J Smith; william wisden
Ligand-gated ion channel subunit partnerships: GABAA receptor alpha6 subunit gene inactivation inhibits delta subunit expression.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1997;17(4):1350-62.
1997: Hartmut Lüddens; Esa R Korpi
Methods for transient expression of hetero-oligomeric ligand-gated ion channels.
Methods in molecular biology (Clifton, N.J.) 1997;83():55-63.
1997: Y Yildirim; L Niemi; G Wong; Esa R Korpi; Per H Rosenberg
Propofol-induced ataxia and hypnosis in rat lines selected for differential alcohol sensitivity.
Pharmacology & toxicology 1997;80(1):44-8.
1996: G Wong; M Kuoppamäki; Jarmo Hietala; Hartmut Lüddens; Erkka Syvälahti; Esa R Korpi
Effects of clozapine metabolites and chronic clozapine treatment on rat brain GABAA receptors.
European journal of pharmacology 1996;314(3):319-23.
1996: Aapo Honkanen; L Vilamo; K Wegelius; Maija Sarviharju; Petri Hyytiä; Esa R Korpi
Alcohol drinking is reduced by a mu 1- but not by a delta-opioid receptor antagonist in alcohol-preferring rats.
European journal of pharmacology 1996;304(1-3):7-13.
1996: Esa R Korpi; P H Seeburg; Hartmut Lüddens
Modulation of GABAA receptor tert-[35S]butylbicyclophosphorothionate binding by antagonists: relationship to patterns of subunit expression.
Journal of neurochemistry 1996;66(5):2179-87.
1996: G Wong; M Sarviharju; M Toropainen; D Matecka; Esa R Korpi
Pharmacologic actions of subtype-selective and novel GABAergic ligands in rat lines with differential sensitivity to ethanol.
Pharmacology, biochemistry, and behavior 1996;53(3):723-30.
1996: Rauno Mäkelä; M Lehtonen; william wisden; Hartmut Lüddens; Esa R Korpi
Blunted furosemide action on cerebellar GABAA receptors in ANT rats selectively bred for high alcohol sensitivity.
Neuropharmacology 1996;35(9-10):1493-502.
1996: william wisden; Esa R Korpi; S Bahn
The cerebellum: a model system for studying GABAA receptor diversity.
Neuropharmacology 1996;35(9-10):1139-60.
1995: Rauno Mäkelä; G Wong; Hartmut Lüddens; Esa R Korpi
Phenotypic and genotypic analysis of rats with cerebellar GABAA receptors composed from mutant and wild-type alpha 6 subunits.
Journal of neurochemistry 1995;65(6):2401-8.
1995: Esa R Korpi; G Wong; H Lüddens
Subtype specificity of gamma-aminobutyric acid type A receptor antagonism by clozapine.
Naunyn-Schmiedeberg's archives of pharmacology 1995;352(4):365-73.
1995: Esa R Korpi; A Herb; Hartmut Lüddens
Effects of ethanol on recombinant rat GABAA receptors: [35S]t-butylbicyclophosphorothionate ([35S]TBPS) binding study.
Pharmacology & toxicology 1995;77(2):87-90.
1995: R Näkki; G Wong; Esa R Korpi
[3H]MK-801 binding in various brain regions of rat lines selected for differential alcohol sensitivity.
Alcohol (Fayetteville, N.Y.) 1995;12(4):335-40.
1995: Aapo Honkanen; T Ovaska; Esa R Korpi
Defective habituation to nociceptive stimulation in alcohol-avoiding ANA rats.
Psychopharmacology 1995;120(1):21-7.
1995: K Wegelius; Esa R Korpi
Ethanol inhibits NMDA-induced toxicity and trophism in cultured cerebellar granule cells.
Acta physiologica Scandinavica 1995;154(1):25-34.
1995: G Wong; Mikko Uusi-Oukari; H C Hansen; PD Suzdak; Esa R Korpi
Characterization of novel ligands for wild-type and natural mutant diazepam-insensitive benzodiazepine receptors.
European journal of pharmacology 1995;289(2):335-42.
1995: Hartmut Lüddens; Esa R Korpi; Peter H Seeburg
GABAA/benzodiazepine receptor heterogeneity: neurophysiological implications.
Neuropharmacology 1995;34(3):245-54.
1995: Esa R Korpi; Thomas Kuner; Peter H Seeburg; Hartmut Lüddens
Selective antagonist for the cerebellar granule cell-specific gamma-aminobutyric acid type A receptor.
Molecular pharmacology 1995;47(2):283-9.
1994: K Wegelius; Aapo Honkanen; Esa R Korpi
Benzodiazepine receptor ligands modulate ethanol drinking in alcohol-preferring rats.
European journal of pharmacology 1994;263(1-2):141-7.
1994: Esa R Korpi; Thomas Kuner; P Kristo; M Köhler; A Herb; Hartmut Lüddens; Peter H Seeburg
Small N-terminal deletion by splicing in cerebellar alpha 6 subunit abolishes GABAA receptor function.
Journal of neurochemistry 1994;63(3):1167-70.
1994: K Tuominen; Maija Sarviharju; Aapo Honkanen; Esa R Korpi
Phenotypic characterization of second generation offspring of alcohol-sensitive ANT and alcohol-insensitive AT rat lines.
Alcohol (Fayetteville, N.Y.) 1994;11(5):379-84.
1994: Erkka Syvälahti; Tiina Pohjalainen; Esa R Korpi; E P Pälvimäki; T Ovaska; M Kuoppamäki; Jarmo Hietala
Dopamine D2 receptor gene expression in rat lines selected for differences in voluntary alcohol consumption.
Alcoholism, clinical and experimental research 1994;18(4):1029-31.
1994: Aapo Honkanen; S J Chrapusta; F Karoum; Esa R Korpi
Alterations in dopamine metabolism by intraperitoneal ethanol in rats selected for high and low ethanol preference: a 3-methoxytyramine study.
Alcohol (Fayetteville, N.Y.) 1994;11(4):323-8.
1993: Thomas Kuner; R Schoepfer; Esa R Korpi
Ethanol inhibits glutamate-induced currents in heteromeric NMDA receptor subtypes.
Neuroreport 1993;5(3):297-300.
1993: Esa R Korpi; Peter H Seeburg
Natural mutation of GABAA receptor alpha 6 subunit alters benzodiazepine affinity but not allosteric GABA effects.
European journal of pharmacology 1993;247(1):23-7.
1993: K Wegelius; T Halonen; Esa R Korpi
Gamma-vinyl GABA decreases voluntary alcohol consumption in alcohol-preferring AA rats.
Pharmacology & toxicology 1993;73(3):150-2.
1993: Maija Sarviharju; Esa R Korpi
Ethanol sensitivity and consumption in F2 hybrid crosses of ANT and AT rats.
Alcohol (Fayetteville, N.Y.) 1993;10(5):415-8.
1993: Esa R Korpi; Hartmut Lüddens
Regional gamma-aminobutyric acid sensitivity of t-butylbicyclophosphoro[35S]thionate binding depends on gamma-aminobutyric acidA receptor alpha subunit.
Molecular pharmacology 1993;44(1):87-92.
1993: Esa R Korpi; Mikko Uusi-Oukari; J Kaivola
Postnatal development of diazepam-insensitive [3H]Ro 15-4513 binding sites.
Neuroscience 1993;53(2):483-8.
1993: C Kleingoor; H A Wieland; Esa R Korpi; Peter H Seeburg; Helmut Kettenmann
Current potentiation by diazepam but not GABA sensitivity is determined by a single histidine residue.
Neuroreport 1993;4(2):187-90.
1993: Esa R Korpi; C Kleingoor; Helmut Kettenmann; Peter H Seeburg
Benzodiazepine-induced motor impairment linked to point mutation in cerebellar GABAA receptor.
Nature 1993;361(6410):356-9.
1993: T Taira; Mikko Uusi-Oukari; Esa R Korpi
Early postnatal treatment with muscimol transiently alters brain GABAA receptors and open-field behavior in rat.
European journal of pharmacology 1993;230(3):307-12.
1993: P Päivärinta; Esa R Korpi
Voluntary ethanol drinking increases locomotor activity in alcohol-preferring AA rats.
Pharmacology, biochemistry, and behavior 1993;44(1):127-32.
1992: Esa R Korpi; P Päivärinta; Anissa Abi-Dargham; Aapo Honkanen; Marc Laruelle; K Tuominen; L A Hilakivi
Binding of serotonergic ligands to brain membranes of alcohol-preferring AA and alcohol-avoiding ANA rats.
Alcohol (Fayetteville, N.Y.) 1992;9(5):369-74.
1992: Esa R Korpi; Mikko Uusi-Oukari; E Castren; PD Suzdak; T Seppälä; Maija Sarviharju; K Tuominen
Cerebellar GABAA receptors in two rat lines selected for high and low sensitivity to moderate alcohol doses: pharmacological and genetic studies.
Alcohol (Fayetteville, N.Y.) 1992;9(3):225-31.
1992: Esa R Korpi; Mikko Uusi-Oukari; K Wegelius; M Casanova; M Zito; J E Kleinman
Cerebellar and frontal cortical benzodiazepine receptors in human alcoholics and chronically alcohol-drinking rats.
Biological psychiatry 1992;31(8):774-86.
1992: Esa R Korpi; K Tuominen; P T Männistö
Hormone responses to sedative drugs and cold exposure in two rat lines with high and low alcohol sensitivity.
Pharmacology, biochemistry, and behavior 1992;41(4):795-9.
1992: Esa R Korpi; Mikko Uusi-Oukari; K Wegelius
Substrate specificity of diazepam-insensitive cerebellar [3H]Ro 15-4513 binding sites.
European journal of pharmacology 1992;213(3):323-9.
1992: Esa R Korpi; Hartmut Lüddens; Peter H Seeburg
GABAA antagonists reveal binding sites for [35S]TBPS in cerebellar granular cell layer.
European journal of pharmacology 1992;211(3):427-8.
1992: T Táira; Tarja Porkka-Heiskanen; Esa R Korpi
Neonatal administration of a GABA-T inhibitor alters central GABAA receptor mechanisms and alcohol drinking in adult rats.
Psychopharmacology 1992;109(1-2):191-7.
1992: Esa R Korpi; Mikko Uusi-Oukari
Cerebellar GABAA receptors and alcohol-related behaviors: focus on diazepam-insensitive [3H]Ro 15-4513 binding.
Advances in biochemical psychopharmacology 1992;47():289-99.
1991: K Tuominen; Esa R Korpi
Diminished stress responses in the alcohol-sensitive ANT rat line.
Pharmacology, biochemistry, and behavior 1991;40(2):409-15.
1991: Esa R Korpi; P Päivärinta; B Sjöholm; Markku Koulu
Hypothalamic monoamines and food intake in alcohol-preferring AA and alcohol-avoiding ANA rats.
Alcohol (Fayetteville, N.Y.) 1991;8(2):137-41.
1991: K Tuominen; Esa R Korpi
Lack of effects of handling habituation and swimming stress on ethanol-induced motor impairment and GABAA receptor function.
Acta physiologica Scandinavica 1991;141(3):409-13.
1990: K Tuominen; L A Hilakivi; P Päivärinta; Esa R Korpi
Behavior of alcohol-preferring AA and alcohol-avoiding ANA rat lines in tests of anxiety and aggression.
Alcohol (Fayetteville, N.Y.) 1990;7(4):349-53.
1990: Mikko Uusi-Oukari; Esa R Korpi
Diazepam sensitivity of the binding of an imidazobenzodiazepine, [3H]Ro 15-4513, in cerebellar membranes from two rat lines developed for high and low alcohol sensitivity.
Journal of neurochemistry 1990;54(6):1980-7.
1990: Esa R Korpi
Effects of alpha 2-adrenergic drugs on the alcohol consumption of alcohol-preferring rats.
Pharmacology & toxicology 1990;66(4):283-6.
1990: K Tuominen; K Hellevuo; Esa R Korpi
Plus-maze behavior and susceptibility to 3-mercaptopropionate-induced seizures in rat lines selected for high and low alcohol sensitivity.
Pharmacology, biochemistry, and behavior 1990;35(3):721-5.
1990: Esa R Korpi; K Tuominen; Mikko Uusi-Oukari; P Saransaari; S S Oja; PD Suzdak
Mechanisms of alcohol intoxication in a rodent model: blunted alcohol-opposing reaction in "alcohol-sensitive" rats.
Annals of medicine 1990;22(4):253-8.
1989: K Hellevuo; K Kiianmaa; Esa R Korpi
Effect of GABAergic drugs on motor impairment from ethanol, barbital and lorazepam in rat lines selected for differential sensitivity to ethanol.
Pharmacology, biochemistry, and behavior 1989;34(2):399-404.
1989: Mikko Uusi-Oukari; Esa R Korpi
Cerebellar GABAA receptor binding and function in vitro in two rat lines developed for high and low alcohol sensitivity.
Neurochemical research 1989;14(8):733-9.
1989: P Päivärinta; Esa R Korpi
Automated method for measuring fighting behavior and locomotor activity of mice.
Physiology & behavior 1989;45(4):857-60.
1989: Esa R Korpi; Mikko Uusi-Oukari
GABAA receptor-mediated chloride flux in brain homogenates from rat lines with differing innate alcohol sensitivities.
Neuroscience 1989;32(2):387-92.
1988: Esa R Korpi; J D Sinclair; P Kaheinen; T Viitamaa; K Hellevuo; K Kiianmaa
Brain regional and adrenal monoamine concentrations and behavioral responses to stress in alcohol-preferring AA and alcohol-avoiding ANA rats.
Alcohol (Fayetteville, N.Y.) 1988;5(5):417-25.
1988: F Lindroos; Esa R Korpi
Effects of moderate ethanol sedation on brain regional 2-deoxyglucose uptake in alcohol-sensitive and alcohol-insensitive rat lines.
Pharmacology, biochemistry, and behavior 1988;30(3):781-6.
1988: P Kaheinen; Esa R Korpi; I Pyykkö; S Mäntysalo; Jaakko Ignatius
Hippocampal rhythmic slow activity in rat lines selected for differences in ethanol-induced motor impairment.
Pharmacology, biochemistry, and behavior 1988;30(1):177-81.
1988: K Hellevuo; Esa R Korpi
Failure of Ro 15-4513 to antagonize ethanol in rat lines selected for differential sensitivity to ethanol and in Wistar rats.
Pharmacology, biochemistry, and behavior 1988;30(1):183-8.
1987: Esa R Korpi; J D Sinclair; O Malminen
Dopamine D2 receptor binding in striatal membranes of rat lines selected for differences in alcohol-related behaviours.
Pharmacology & toxicology 1987;61(2):94-7.
1987: Esa R Korpi; F Lindroos; I Pyykkö; O Malminen; P Kaheinen; Jaakko Ignatius; S Mäntysalo
Ethanol-induced modulation of hippocampal EEG and cerebral 2-deoxyglucose accumulation in rat lines with differing alcohol sensitivities.
Alcohol and alcoholism (Oxford, Oxfordshire). Supplement 1987;1():713-7.
1983: Esa R Korpi; Simo S Oja
Mechanism of l-histidine-induced stimulation of amino acid transport in slices of rat cerebral cortex.
Neurochemistry international 1983;5(6):793-801.
1983: J Heredero; Esa R Korpi; Simo S Oja
Tetanus toxin treatment in vitro inhibits the release of GABA from rat cerebral cortex slices evoked by high K(+) and Na(+)-free media.
Neurochemistry international 1983;5(1):137-43.