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Olle Korsgren

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Oskar Skog; Stella Korsgren; Asa Melhus; Olle Korsgren
Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease.
Sara F Hansson; Stella Korsgren; Fredrik Pontén; Olle Korsgren
Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins.
Andrew S Friberg; Olle Korsgren; Mikko Hellgren
A vast amount of enzyme activity fails to be absorbed within the human pancreas: implications for cost-effective islet isolation procedures.

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2013: Oskar Skog; Stella Korsgren; Asa Melhus; Olle Korsgren
Revisiting the notion of type 1 diabetes being a T-cell-mediated autoimmune disease.
Current opinion in endocrinology, diabetes, and obesity 2013;20(2):118-23.
2013: Sara F Hansson; Stella Korsgren; Fredrik Pontén; Olle Korsgren
Enteroviruses and the pathogenesis of type 1 diabetes revisited: cross-reactivity of enterovirus capsid protein (VP1) antibodies with human mitochondrial proteins.
The Journal of pathology 2013;229(5):719-28.
2013: Andrew S Friberg; Olle Korsgren; Mikko Hellgren
A vast amount of enzyme activity fails to be absorbed within the human pancreas: implications for cost-effective islet isolation procedures.
Transplantation 2013;95(6):e36-8.
2013: A K Lidehäll; G Malm; Fredrik Sund; Thomas H Tötterman; U Ewald; E Karltorp; Olle Korsgren; Ilona Lewensohn-Fuchs; Mona-Lisa Engman; Britt-Marie Eriksson
Cytomegalovirus-specific CD4 and CD8 T cell responses in infants and children.
Scandinavian journal of immunology 2013;77(2):135-43.
2013: Di Yu; Rachel Adamson; Xiaolong Fan; Karin Forsberg-Nilsson; Chuan Jin; Olle Korsgren; Katarina Le Blanc; Norman Maitland; Berith Nilsson; Mohanraj Ramachandran; Lene Uhrbom; Bengt Westermark; Jing Xu; Magnus Essand
Adenovirus serotype 5 vectors with Tat-PTD modified hexon and serotype 35 fiber show greatly enhanced transduction capacity of primary cell cultures.
PloS one 2013;8(1):e54952.
2013: Christian Molnár; Gunnar Tufveson; Lars Wennberg; Christian Berne; Magnus Essand; Erik Larsson; Olle Korsgren
Islet engraftment and revascularization in clinical and experimental transplantation.
Cell transplantation 2013;22(2):243-51.
2012: Petri Ylipaasto; Tuulikki Seppänen-Laakso; Teemu Smura; H Ahlfors; Jochem M D Galama; P Gopalacharyulu; S Kaijalainen; Olle Korsgren; R Lahesmaa; J R T Lakey; M Oresic; Anja Paananen; Lorenzo Piemonti; Merja Roivainen
Enterovirus-induced gene expression profile is critical for human pancreatic islet destruction.
Diabetologia 2012;55(12):3273-83.
2012: Sana Asif; Heide Brandhorst; Simone Hoeger; Carl Jorns; Olle Korsgren; Erik Larsson; Tomas Lorant; Peetra U Magnusson; Johan Nordström; Greg Nowak; Amir Sedigh; Sonja Theisinger; Lars Wennberg; Daniel Brandhorst
Oxygen-charged HTK-F6H8 emulsion reduces ischemia-reperfusion injury in kidneys from brain-dead pigs.
The Journal of surgical research 2012;178(2):959-67.
2012: Stella Korsgren; Torbjörn Lundgren; Asa Melhus; Ylva Molin; Kaija Salmela; Olle Korsgren
On the etiology of type 1 diabetes: a new animal model signifying a decisive role for bacteria eliciting an adverse innate immunity response.
The American journal of pathology 2012;181(5):1735-48.
2012: Bengt von Zur-Mühlen; Gunnar Tufveson; Olle Korsgren
Insulin independence after conversion from tacrolimus to cyclosporine in islet transplantation.
Transplant international : official journal of the European Society for Organ Transplantation 2012;25(10):e108-10.
2012: Jalal Taneera; Petter Vikman; Claes B Wollheim; Enming Zhang; Yuedan Zhou; Emma Ahlqvist; Jonathan L S Esguerra; Joao Fadista; Ola Hansson; Xing-Jun Jing; Anna Jonsson; Olle Korsgren; Ulrika Krus; Stefan Lang; Valeriya Lyssenko; Hemang Parikh; Erik Renström; Anders Rosengren; Albert Salehi; Amitabh Sharma; Arvind Soni; Leif Groop
A systems genetics approach identifies genes and pathways for type 2 diabetes in human islets.
Cell metabolism 2012;16(1):122-34.
2012: Guido Moll; Bo Nilsson; Kristina Nilsson-Ekdahl; Ida Rasmusson-Duprez; Olle Ringdén; Javier Sanchez; Yuji Teramura; Lena von Bahr; Anne-Marie Connolly-Andersen; Graciela Elgue; Lillemor Funke; Osama A Hamad; Olle Korsgren; Helena Lönnies; Peetra U Magnusson; Katarina Le Blanc
Are therapeutic human mesenchymal stromal cells compatible with human blood?
Stem cells (Dayton, Ohio) 2012;30(7):1565-74.
2012: José Caballero-Corbalán; Marie Felldin; Aksel Foss; Olle Korsgren; Helene Malm; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Heide Brandhorst; Daniel Brandhorst
Using HTK for prolonged pancreas preservation prior to human islet isolation.
The Journal of surgical research 2012;175(1):163-8.
2012: Cecilia Lindskog; Fredrik Pontén; Jan W Eriksson; Lars Johansson; Olle Korsgren; Angelika Danielsson
Novel pancreatic beta cell-specific proteins: antibody-based proteomics for identification of new biomarker candidates.
Journal of proteomics 2012;75(9):2611-20.
2012: Meenal Banerjee; Olle Korsgren; Jaan Palgi; Ismo Virtanen; Timo Otonkoski
Proliferation and plasticity of human beta cells on physiologically occurring laminin isoforms.
Molecular and cellular endocrinology 2012;355(1):78-86.
2012: Olof Eriksson; Olle Korsgren; Bengt Långström; Anders Sundin; Elisabeth Blom; F Carlsson; Irina Velikyan
Preclinical evaluation of a 68Ga-labeled biotin analogue for applications in islet transplantation.
Nuclear medicine and biology 2012;39(3):415-21.
2012: Andrew S Friberg; Trond Jenssen; Marie Felldin; Lauri Kyllönen; Torbjörn Lundgren; Helene Malm; Bo Nilsson; Annika Tibell; Gunnar Tufveson; Olle Korsgren
Transplanted functional islet mass: donor, islet preparation, and recipient factors influence early graft function in islet-after-kidney patients.
Transplantation 2012;93(6):632-8.
2012: Gunilla T Westermark; Arne Andersson; Alberto M Davalli; Franco Folli; Tatsuya Kin; Olle Korsgren; Antonio Secchi; A M James Shapiro; Christian Toso; Gunnar Tufveson; Per Westermark
Further evidence for amyloid deposition in clinical pancreatic islet grafts.
Transplantation 2012;93(2):219-23.
2012: David Berglund; Olle Korsgren; Tomas Lorant; Karin Schneider; Gunnar Tufveson; Björn Carlsson
Isolation, expansion and functional assessment of CD4+CD25+FoxP3+ regulatory T cells and Tr1 cells from uremic patients awaiting kidney transplantation.
Transplant immunology 2012;26(1):27-33.
2011: Bo Nilsson; Kristina N Ekdahl; Olle Korsgren
Control of instant blood-mediated inflammatory reaction to improve islets of Langerhans engraftment.
Current opinion in organ transplantation 2011;16(6):620-6.
2011: Olof Eriksson; Olle Korsgren; Torbjörn Lundgren; Bo Nilsson; Arian Sadeghi; Björn Carlsson; Torsten Eich; Thomas Tötterman; Anders Sundin
Distribution of adoptively transferred porcine T-lymphoblasts tracked by (18)F-2-fluoro-2-deoxy-D-glucose and position emission tomography.
Nuclear medicine and biology 2011;38(6):827-33.
2011: Oskar Skog; Olle Korsgren; Gun Frisk
Modulation of innate immunity in human pancreatic islets infected with enterovirus in vitro.
Journal of medical virology 2011;83(4):658-64.
2011: Elisabet K Gustafson; Graciela Elgue; Robin D Hughes; Ragai R Mitry; Javier Sanchez; Ulf Haglund; Staffan Meurling; Anil Dhawan; Olle Korsgren; Bo Nilsson
The instant blood-mediated inflammatory reaction characterized in hepatocyte transplantation.
Transplantation 2011;91(6):632-8.
2011: Andrew S Friberg; Heide Brandhorst; Peter Buchwald; Masafumi Goto; Camillo Ricordi; Daniel Brandhorst; Olle Korsgren
Quantification of the islet product: presentation of a standardized current good manufacturing practices compliant system with minimal variability.
Transplantation 2011;91(6):677-83.
2011: Karlis Purins; Amir Sedigh; Christian Molnar; Leif Jansson; Olle Korsgren; Tomas Lorant; Gunnar Tufveson; Lars Wennberg; Lars Wiklund; Anders Lewén; Per Enblad
Standardized experimental brain death model for studies of intracranial dynamics, organ preservation, and organ transplantation in the pig.
Critical care medicine 2011;39(3):512-7.
2011: Ida Rasmusson Duprez; Ulrika Johansson; Bo Nilsson; Olle Korsgren; Peetra U Magnusson
Preparatory studies of composite mesenchymal stem cell islets for application in intraportal islet transplantation.
Upsala journal of medical sciences 2011;116(1):8-17.
2011: Arian Sadeghi; Linnea Pauler; Cecilia Annerén; Andrew Friberg; Daniel Brandhorst; Olle Korsgren; Thomas H Tötterman
Large-scale bioreactor expansion of tumor-infiltrating lymphocytes.
Journal of immunological methods 2011;364(1-2):94-100.
2011: Monica Sandberg; Fredrik Carlsson; Bo Nilsson; Olle Korsgren; Per-Ola Carlsson; Leif Jansson
Syngeneic islet transplantations into the submandibular gland of mice.
Transplantation 2011;91(2):e17-9.
2011: Thierry Berney; Olle Korsgren; Andrew Posselt; Antonello Pileggi
Islet Transplantation & β-Cell Replacement Therapies for Diabetes.
Journal of transplantation 2011;2011():157840.
2011: Mahabuba Jahan; Lars Johansson; Peter Johnström; Olle Korsgren; Anders Sundin; Olof Eriksson; Christer Halldin
Decreased defluorination using the novel beta-cell imaging agent [18F]FE-DTBZ-d4 in pigs examined by PET.
EJNMMI research 2011;1(1):33.
2011: Magnus U Ståhle; Olle Korsgren; Daniel Brandhorst; Folke Knutson
Pathogen inactivation of human serum facilitates its clinical use for islet cell culture and subsequent transplantation.
Cell transplantation 2011;20(5):775-81.
2010: Gustaf Christoffersson; Johanna Henriksnäs; Lars Johansson; Charlotte Rolny; Håkan Ahlström; José Caballero-Corbalan; Ralf Segersvärd; Johan Permert; Olle Korsgren; Per-Ola Carlsson; Mia Phillipson
Clinical and experimental pancreatic islet transplantation to striated muscle: establishment of a vascular system similar to that in native islets.
Diabetes 2010;59(10):2569-78.
2010: Heide Brandhorst; Sana Asif; Karin Andersson; Johanna Mönch; Olaf Friedrich; Nicole Rämsch-Günther; Christian Rämsch; Melanie Steffens; Jörg Lambrecht; Thomas Schräder; Manfred Kurfürst; Helene H Andersson; Marie Felldin; Aksel Foss; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Olle Korsgren; Daniel Brandhorst
The effect of truncated collagenase class I isomers on human islet isolation outcome.
Transplantation 2010;90(3):334-5.
2010: Cecilia Lindskog; Anna Asplund; Margareta Engkvist; Mathias Uhlen; Olle Korsgren; Fredrik Ponten
Antibody-based proteomics for discovery and exploration of proteins expressed in pancreatic islets.
Discovery medicine 2010;9(49):565-78.
2010: Tormod Lund; Olle Korsgren; Ingrid A Aursnes; Hanne Scholz; Aksel Foss
Sustained reversal of diabetes following islet transplantation to striated musculature in the rat.
The Journal of surgical research 2010;160(1):145-54.
2010: Fredrik Sund; Anna-Karin Lidehäll; Kerstin Claesson; Aksel Foss; Thomas H Tötterman; Olle Korsgren; Britt-Marie Eriksson
CMV-specific T-cell immunity, viral load, and clinical outcome in seropositive renal transplant recipients: a pilot study.
Clinical transplantation 2010;24(3):401-9.
2010: M Ståhle; B Carlsson; K Le Blanc; Olle Korsgren; Folke Knutson
Photochemical pathogen inactivation of human serum enables its large-scale application in clinical cell transplantation.
Vox sanguinis 2010;98(3 Pt 1):e364-5.
2010: Olof Eriksson; Mahabuba Jahan; Peter Johnström; Olle Korsgren; Anders Sundin; Christer Halldin; Lars Johansson
In vivo and in vitro characterization of [18F]-FE-(+)-DTBZ as a tracer for beta-cell mass.
Nuclear medicine and biology 2010;37(3):357-63.
2010: T Lund; S M Mangsbo; Hanne Scholz; P Gjorstrup; T H Tötterman; Olle Korsgren; Aksel Foss
Resolvin E1 reduces proinflammatory markers in human pancreatic islets in vitro.
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association 2010;118(4):237-44.
2010: Sanja Cabric; Javier Sanchez; Ulrika Johansson; Rolf Larsson; Bo Nilsson; Olle Korsgren; Peetra U Magnusson
Anchoring of vascular endothelial growth factor to surface-immobilized heparin on pancreatic islets: implications for stimulating islet angiogenesis.
Tissue engineering. Part A 2010;16(3):961-70.
2010: Angela Koh; Peter Senior; Abdul Salam; Tatsuya Kin; Sharleen Imes; Parastoo Dinyari; Andrew Malcolm; Christian Toso; Bo Nilsson; Olle Korsgren; A M James Shapiro
Insulin-heparin infusions peritransplant substantially improve single-donor clinical islet transplant success.
Transplantation 2010;89(4):465-71.
2010: S Jacobson; F Heuts; J Juarez; Monica Hultcrantz; Olle Korsgren; M Svensson; Martin Rottenberg; Malin Flodström-Tullberg
Alloreactivity but failure to reject human islet transplants by humanized Balb/c/Rag2gc mice.
Scandinavian journal of immunology 2010;71(2):83-90.
2010: Heide Brandhorst; Sana Asif; Karin Andersson; Bastian Theisinger; Helene H Andersson; Marie Felldin; Aksel Foss; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Olle Korsgren; Daniel Brandhorst
A new oxygen carrier for improved long-term storage of human pancreata before islet isolation.
Transplantation 2010;89(2):155-60.
2010: Bo Nilsson; Olle Korsgren; John D Lambris; Kristina Nilsson Ekdahl
Can cells and biomaterials in therapeutic medicine be shielded from innate immune recognition?
Trends in immunology 2010;31(1):32-8.
2010: Heide Brandhorst; A Friberg; Bo Nilsson; H H Andersson; Marie Felldin; Aksel Foss; K Salmela; Annika Tibell; G Tufveson; Olle Korsgren; Daniel Brandhorst
Large-scale comparison of Liberase HI and collagenase NB1 utilized for human islet isolation.
Cell transplantation 2010;19(1):3-8.
2009: José Caballero-Corbalán; Andrew S Friberg; Heide Brandhorst; Bo Nilsson; Helene H Andersson; Marie Felldin; Aksel Foss; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Olle Korsgren; Daniel Brandhorst
Vitacyte collagenase HA: a novel enzyme blend for efficient human islet isolation.
Transplantation 2009;88(12):1400-2.
2009: Olof Eriksson; Torsten Eich; Anders Sundin; Annika Tibell; Gunnar Tufveson; H Andersson; Marie Felldin; Aksel Foss; L Kyllönen; Bengt Langstrom; Bo Nilsson; Olle Korsgren; Torbjörn Lundgren
Positron emission tomography in clinical islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2009;9(12):2816-24.
2009: Olle Korsgren; Bo Nilsson
Improving islet transplantation: a road map for a widespread application for the cure of persons with type I diabetes.
Current opinion in organ transplantation 2009;14(6):683-7.
2009: Heide Brandhorst; Bastian Theisinger; Hideyuki Yamaya; Johanna Henriksnäs; Per-Ola Carlsson; Olle Korsgren; Daniel Brandhorst
Perfluorohexyloctane improves long-term storage of rat pancreata for subsequent islet isolation.
Transplant international : official journal of the European Society for Organ Transplantation 2009;22(10):1017-22.
2009: Annika Moëll; Oskar Skog; Erik Ahlin; Olle Korsgren; Gun Frisk
Antiviral effect of nicotinamide on enterovirus-infected human islets in vitro: effect on virus replication and chemokine secretion.
Journal of medical virology 2009;81(6):1082-7.
2009: Heide Brandhorst; Andrew Friberg; Helena H Andersson; Marie Felldin; Aksel Foss; Kaija Salmela; Torbjörn Lundgren; Annika Tibell; Gunnar Tufveson; Olle Korsgren; Daniel Brandhorst
The importance of tryptic-like activity in purified enzyme blends for efficient islet isolation.
Transplantation 2009;87(3):370-5.
2008: Timo Otonkoski; M Banerjee; Olle Korsgren; Lars-Eric Thornell; Ismo Virtanen
Unique basement membrane structure of human pancreatic islets: implications for beta-cell growth and differentiation.
Diabetes, obesity & metabolism 2008;10 Suppl 4():119-27.
2008: Rolf Spirig; THUSITHA GAJANAYAKE; Olle Korsgren; Bo Nilsson; Robert Rieben
Low molecular weight dextran sulfate as complement inhibitor and cytoprotectant in solid organ and islet transplantation.
Molecular immunology 2008;45(16):4084-94.
2008: Ulrika Johansson; Ida Rasmusson; Simone Niclou; Naomi Forslund; Linda Gustavsson; Bo Nilsson; Olle Korsgren; Peetra U Magnusson
Formation of composite endothelial cell-mesenchymal stem cell islets: a novel approach to promote islet revascularization.
Diabetes 2008;57(9):2393-401.
2008: Gunilla T Westermark; Per Westermark; Christian Berne; Olle Korsgren
Widespread amyloid deposition in transplanted human pancreatic islets.
The New England journal of medicine 2008;359(9):977-9.
2008: Masafumi Goto; Jenny Tjernberg; Denis Dufrane; Graciela Elgue; Daniel Brandhorst; Kristina Nilsson Ekdahl; Heidi Brandhorst; Lars Wennberg; Yoshimochi Kurokawa; Susumu Satomi; John D Lambris; Pierre Gianello; Olle Korsgren; Bo Nilsson
Dissecting the instant blood-mediated inflammatory reaction in islet xenotransplantation.
Xenotransplantation 2008;15(4):225-34.
2008: I Virtanen; M Banerjee; Jaan Palgi; Olle Korsgren; A Lukinius; Lars-Eric Thornell; Y Kikkawa; K Sekiguchi; M Hukkanen; Y T Konttinen; Timo Otonkoski
Blood vessels of human islets of Langerhans are surrounded by a double basement membrane.
Diabetologia 2008;51(7):1181-91.
2008: Tormod Lund; Bjarte Fosby; Olle Korsgren; Hanne Scholz; Aksel Foss
Glucocorticoids reduce pro-inflammatory cytokines and tissue factor in vitro and improve function of transplanted human islets in vivo.
Transplant international : official journal of the European Society for Organ Transplantation 2008;21(7):669-78.
2008: Sanja Cabric; Torsten Eich; Javier Sanchez; Bo Nilsson; Olle Korsgren; Rolf Larsson
A new method for incorporating functional heparin onto the surface of islets of Langerhans.
Tissue engineering. Part C, Methods 2008;14(2):141-7.
2008: Henrik von Euler; Arian Sadeghi; Björn Carlsson; Patricio Rivera; Angelica Loskog; T Segall; Olle Korsgren; Thomas H Tötterman
Efficient adenovector CD40 ligand immunotherapy of canine malignant melanoma.
Journal of immunotherapy (Hagerstown, Md. : 1997) 2008;31(4):377-84.
2008: Jenny Tjernberg; Kristina N Ekdahl; John D Lambris; Olle Korsgren; Bo Nilsson
Acute antibody-mediated complement activation mediates lysis of pancreatic islets cells and may cause tissue loss in clinical islet transplantation.
Transplantation 2008;85(8):1193-9.
2008: Olle Korsgren; Carl G Groth
Co-transplantation of human and pig islets.
Xenotransplantation 2008;15(2):112.
2008: Heide Brandhorst; B Muehling; H Yamaya; J Henriksnaes; Per-Ola Carlsson; Olle Korsgren; Daniel Brandhorst
New class of oxygen carriers improves islet isolation from long-term stored rat pancreata.
Transplantation proceedings 2008;40(2):393-4.
2008: Heide Brandhorst; N Raemsch-Guenther; C Raemsch; O Friedrich; M Kurfuerst; Olle Korsgren; Daniel Brandhorst
Degraded collagenase deteriorates islet viability.
Transplantation proceedings 2008;40(2):370-1.
2008: Heide Brandhorst; Nicole Raemsch-Guenther; Christian Raemsch; Olaf Friedrich; Silke Huettler; Manfred Kurfuerst; Olle Korsgren; Daniel Brandhorst
The ratio between collagenase class I and class II influences the efficient islet release from the rat pancreas.
Transplantation 2008;85(3):456-61.
2008: Ehab Rafael; Annika Tibell; Mikael Rydén; Torbjörn Lundgren; Lars Sävendahl; B Borgström; Urban Arnelo; Bengt Isaksson; Bo Nilsson; Olle Korsgren; Johan Permert
Intramuscular autotransplantation of pancreatic islets in a 7-year-old child: a 2-year follow-up.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2008;8(2):458-62.
2008: Olle Korsgren; Torbjörn Lundgren; Marie Felldin; Aksel Foss; Bengt Isaksson; J Permert; Nils H Persson; Ehab Rafael; Mikael Rydén; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Bo Nilsson
Optimising islet engraftment is critical for successful clinical islet transplantation.
Diabetologia 2008;51(2):227-32.
2008: A S Friberg; M Ståhle; Heide Brandhorst; Olle Korsgren; Daniel Brandhorst
Human islet separation utilizing a closed automated purification system.
Cell transplantation 2008;17(12):1305-13.
2007: Torsten Eich; Olof Eriksson; Anders Sundin; Sergio Estrada; Daniel Brandhorst; Heide Brandhorst; Bengt Langstrom; Bo Nilsson; Olle Korsgren; Torbjörn Lundgren
Positron emission tomography: a real-time tool to quantify early islet engraftment in a preclinical large animal model.
Transplantation 2007;84(7):893-8.
2007: José Caballero-Corbalán; Torsten Eich; Torbjörn Lundgren; Aksel Foss; Marie Felldin; Ragnar Källen; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Olle Korsgren; Daniel Brandhorst
No beneficial effect of two-layer storage compared with UW-storage on human islet isolation and transplantation.
Transplantation 2007;84(7):864-9.
2007: Monica Hultcrantz; Michael H Hühn; Monika Wolf; Annika Olsson; Stella Jacobson; Bryan R Williams; Olle Korsgren; Malin Flodström-Tullberg
Interferons induce an antiviral state in human pancreatic islet cells.
Virology 2007;367(1):92-101.
2007: Sanja Cabric; Javier Sanchez; Torbjörn Lundgren; Aksel Foss; Marie Felldin; Ragnar Källen; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Rolf Larsson; Olle Korsgren; Bo Nilsson
Islet surface heparinization prevents the instant blood-mediated inflammatory reaction in islet transplantation.
Diabetes 2007;56(8):2008-15.
2007: Ru Gao; Jarkko Ustinov; Olle Korsgren; Timo Otonkoski
Effects of immunosuppressive drugs on in vitro neogenesis of human islets: mycophenolate mofetil inhibits the proliferation of ductal cells.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2007;7(4):1021-6.
2007: Anna-Karin Berg; Annika Olsson; Olle Korsgren; Gun Frisk
Antiviral treatment of Coxsackie B virus infection in human pancreatic islets.
Antiviral research 2007;74(1):65-71.
2007: Asma Elshebani; Annika Olsson; Jan Westman; Torsten Tuvemo; Olle Korsgren; Gun Frisk
Effects on isolated human pancreatic islet cells after infection with strains of enterovirus isolated at clinical presentation of type 1 diabetes.
Virus research 2007;124(1-2):193-203.
2007: Ru Gao; Jarkko Ustinov; Olle Korsgren; Milla Mikkola; Karolina Lundin; Timo Otonkoski
Maturation of in vitro-generated human islets after transplantation in nude mice.
Molecular and cellular endocrinology 2007;264(1-2):28-34.
2006: Mats Engstrand; Erik Larsson; Mansour Naghibi; Gunnar Tufveson; Olle Korsgren; Cecilia Johnsson
Lymphocyte propagation from biopsies of kidney allografts.
Transplant immunology 2006;16(3-4):215-9.
2006: Anna-Karin Berg; Olle Korsgren; Gun Frisk
Induction of the chemokine interferon-gamma-inducible protein-10 in human pancreatic islets during enterovirus infection.
Diabetologia 2006;49(11):2697-703.
2006: Helena Johansson; Masafumi Goto; Denis Dufrane; Agneta Siegbahn; Graciela Elgue; Pierre Gianello; Olle Korsgren; Bo Nilsson
Low molecular weight dextran sulfate: a strong candidate drug to block IBMIR in clinical islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2006;6(2):305-12.
2006: Sanja Cabric; Graciela Elgue; Bo Nilsson; Olle Korsgren; Peter Schmidt
Adenovirus-mediated expression of the anticoagulant hirudin in human islets: a tool to make the islets biocompatible to blood.
Cell transplantation 2006;15(8-9):759-67.
2005: Bo Nilsson; Christian Berne; Olle Korsgren
The recent finding that tissue factor is produced by the pancreatic islets constitutes a possible link between insulin resistance and cardiovascular disease.
American journal of therapeutics 2005;12(6):551-4.
2005: Ulrika Johansson; Graciela Elgue; Bo Nilsson; Olle Korsgren
Composite islet-endothelial cell grafts: a novel approach to counteract innate immunity in islet transplantation.
American journal of transplantation : official journal of the American Society of Transplantation and the American Society of Transplant Surgeons 2005;5(11):2632-9.
2005: Peter Schmidt; Anna Forsman; Göran Andersson; Jonas Blomberg; Olle Korsgren
Pig islet xenotransplantation: activation of porcine endogenous retrovirus in the immediate post-transplantation period.
Xenotransplantation 2005;12(6):450-6.
2005: Ru Gao; Jarkko Ustinov; Olle Korsgren; Timo Otonkoski
In vitro neogenesis of human islets reflects the plasticity of differentiated human pancreatic cells.
Diabetologia 2005;48(11):2296-304.
2005: L Moberg; Olle Korsgren; Bo Nilsson
Neutrophilic granulocytes are the predominant cell type infiltrating pancreatic islets in contact with ABO-compatible blood.
Clinical and experimental immunology 2005;142(1):125-31.
2005: Anna K Lidehall; Fredrik Sund; Tobias Lundberg; Britt-Marie Eriksson; Thomas H Tötterman; Olle Korsgren
T cell control of primary and latent cytomegalovirus infections in healthy subjects.
Journal of clinical immunology 2005;25(5):473-81.
2005: Petri Ylipaasto; Burak Kutlu; Suvi Rasilainen; Joanne Rasschaert; K Salmela; H Teerijoki; Olle Korsgren; R Lahesmaa; Tapani Hovi; Decio L Eizirik; Timo Otonkoski; Merja Roivainen
Global profiling of coxsackievirus- and cytokine-induced gene expression in human pancreatic islets.
Diabetologia 2005;48(8):1510-22.
2005: Helena Johansson; Agneta Lukinius; Lisa Moberg; Torbjörn Lundgren; Christian Berne; Aksel Foss; Marie Felldin; Ragnar Källen; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Kristina Nilsson Ekdahl; Graciela Elgue; Olle Korsgren; Bo Nilsson
Tissue factor produced by the endocrine cells of the islets of Langerhans is associated with a negative outcome of clinical islet transplantation.
Diabetes 2005;54(6):1755-62.
2005: Olle Korsgren; Bo Nilsson; Christian Berne; Marie Felldin; Aksel Foss; R Kallen; Torbjörn Lundgren; Kaija Salmela; Annika Tibell; Gunnar Tufveson
Current status of clinical islet transplantation.
Transplantation 2005;79(10):1289-93.
2005: Annika Olsson; Ulrika Johansson; Olle Korsgren; Gun Frisk
Inflammatory gene expression in Coxsackievirus B-4-infected human islets of Langerhans.
Biochemical and biophysical research communications 2005;330(2):571-6.
2005: Masafumi Goto; Ulrika Johansson; Torsten Eich; T Lundgrem; Margareta Engkvist; Marie Felldin; Aksel Foss; R Kallen; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Bo Nilsson; Olle Korsgren
Key factors for human islet isolation and clinical transplantation.
Transplantation proceedings 2005;37(2):1315-6.
2005: Masafumi Goto; Torsten Eich; M Stahle; A Malmborg; Margareta Engkvist; Olle Korsgren
Technical improvement of human pancreatic islet isolation.
Transplantation proceedings 2005;37(2):1313-4.
2005: Lars Wennberg; Masafumi Goto; Akira Maeda; Zhensung Song; Christopher Benjamin; Carl G Groth; Olle Korsgren
The efficacy of CD40 ligand blockade in discordant pig-to-rat islet xenotransplantation is correlated with an immunosuppressive effect of immunoglobulin.
Transplantation 2005;79(2):157-64.
2004: Masafumi Goto; Torsten Eich; Marie Felldin; Aksel Foss; Ragnar Källen; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Keisei Fujimori; Margareta Engkvist; Olle Korsgren
Refinement of the automated method for human islet isolation and presentation of a closed system for in vitro islet culture.
Transplantation 2004;78(9):1367-75.
2004: Peter Schmidt; Henrik Krook; Masafumi Goto; Olle Korsgren
MyD88-dependent toll-like receptor signalling is not a requirement for fetal islet xenograft rejection in mice.
Xenotransplantation 2004;11(4):347-52.
2004: Angelica Loskog; Helena Dzojic; Sofia Vikman; Christina Ninalga; Magnus Essand; Olle Korsgren; Thomas H Totterman
Adenovirus CD40 ligand gene therapy counteracts immune escape mechanisms in the tumor Microenvironment.
Journal of immunology (Baltimore, Md. : 1950) 2004;172(11):7200-5.
2004: Masafumi Goto; Helena Johansson; A Maeda; Graciela Elgue; Olle Korsgren; Bo Nilsson
Low-molecular weight dextran sulfate abrogates the instant blood-mediated inflammatory reaction induced by adult porcine islets both in vitro and in vivo.
Transplantation proceedings 2004;36(4):1186-7.
2004: Lars Wennberg; Zhensung Song; W Bennet; John Sandberg; B Sundberg; A Thall; Olle Korsgren
Importance of the Gal alpha1-3 Gal antigen in discordant islet xenotransplantation: immunosuppression, which inhibits porcine islet xenograft rejection in ordinary mice, is equally effective in Gal-knockout mice.
Transplantation 2004;77(8):1275-80.
2004: Bilal Mirza; Henrik Krook; Per Andersson; Lena C Larsson; Olle Korsgren; Håkan Widner
Intracerebral cytokine profiles in adult rats grafted with neural tissue of different immunological disparity.
Brain research bulletin 2004;63(2):105-18.
2004: Masafumi Goto; Helena Johansson; Akira Maeda; Graciela Elgue; Olle Korsgren; Bo Nilsson
Low molecular weight dextran sulfate prevents the instant blood-mediated inflammatory reaction induced by adult porcine islets.
Transplantation 2004;77(5):741-7.
2004: Masafumi Goto; Carl G Groth; Bo Nilsson; Olle Korsgren
Intraportal pig islet xenotransplantation into athymic mice as an in vivo model for the study of the instant blood-mediated inflammatory reaction.
Xenotransplantation 2004;11(2):195-202.
2004: Peter Schmidt; Göran Andersson; Jonas Blomberg; Anders Malmsten; Olle Korsgren
Possible transmission of zoonoses in xenotransplantation: porcine endogenous retroviruses (PERVs) from an immunological point of view.
Acta veterinaria Scandinavica. Supplementum 2004;99():27-34.
2004: Timo Otonkoski; Olle Korsgren; Kaija Salmela
[Replacement therapy with beta-cells: the way to treat diabetes in the future?].
Duodecim; lääketieteellinen aikakauskirja 2004;120(9):1133-4.
2003: Lisa Moberg; Annika Olsson; Christian Berne; Marie Felldin; Aksel Foss; Ragnar Källen; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Bo Nilsson; Olle Korsgren
Nicotinamide inhibits tissue factor expression in isolated human pancreatic islets: implications for clinical islet transplantation.
Transplantation 2003;76(9):1285-8.
2003: Ulrika Johansson; Annika Olsson; Susanne Gabrielsson; Bo Nilsson; Olle Korsgren
Inflammatory mediators expressed in human islets of Langerhans: implications for islet transplantation.
Biochemical and biophysical research communications 2003;308(3):474-9.
2003: Ru Gao; Jarkko Ustinov; Mari-Anne Pulkkinen; Karolina Lundin; Olle Korsgren; Timo Otonkoski
Characterization of endocrine progenitor cells and critical factors for their differentiation in human adult pancreatic cell culture.
Diabetes 2003;52(8):2007-15.
2003: Tomas Lorant; Henrik Krook; Jacob Wilton; Michael Olausson; Gunnar Tufveson; Olle Korsgren; Cecilia Johnsson
Intragraft cytokine mRNA expression in rejecting and non-rejecting vascularized xenografts.
Xenotransplantation 2003;10(4):311-24.
2003: Olle Korsgren; Leo H Buhler; Carl-Gustav Groth
Toward clinical trials of islet xenotransplantation.
Xenotransplantation 2003;10(4):289-92.
2003: Peter Schmidt; Henrik Krook; Akira Maeda; Olle Korsgren; Birgitta Benda
A new murine model of islet xenograft rejection: graft destruction is dependent on a major histocompatibility-specific interaction between T-cells and macrophages.
Diabetes 2003;52(5):1111-8.
2003: Guosheng Wu; Olle Korsgren; Shibo Sun; Nico van Rooijen; Annika Tibell
Effect of plasma exchange in combination with deoxyspergualin on the survival of guinea-pig hearts in macrophage-depleted C6-deficient rats.
Xenotransplantation 2003;10(3):214-22.
2003: A Maeda; M Goto; J Zhang; W Bennet; Carl G Groth; Olle Korsgren; Lars Wennberg
Immunosuppression with FTY720 and cyclosporine A inhibits rejection of adult porcine islet xenografts in rats.
Transplantation 2003;75(8):1409-14.
2003: Mats Engstrand; A K Lidehall; Thomas H Totterman; B Herrman; Britt-Marie Eriksson; Olle Korsgren
Cellular responses to cytomegalovirus in immunosuppressed patients: circulating CD8+ T cells recognizing CMVpp65 are present but display functional impairment.
Clinical and experimental immunology 2003;132(1):96-104.
2003: Peter Schmidt; Masafumi Goto; Brigitte Le Mauff; Ignacio Anegon; Olle Korsgren
Adenovirus-mediated expression of human CD55 or CD59 protects adult porcine islets from complement-mediated cell lysis by human serum.
Transplantation 2003;75(5):697-702.
2002: Lisa Moberg; H Johansson; Agneta Lukinius; Christian Berne; Aksel Foss; Ragnar Källen; Ø Østraat; Kaija Salmela; Annika Tibell; Gunnar Tufveson; Graciela Elgue; K Nilsson Ekdahl; Olle Korsgren; Bo Nilsson
Production of tissue factor by pancreatic islet cells as a trigger of detrimental thrombotic reactions in clinical islet transplantation.
Lancet 2002;360(9350):2039-45.
2002: Henrik Krook; Lars Wennberg; Anette Hagberg; Zhenshun Song; Carl-Gustav Groth; Olle Korsgren
Immunosuppressive drugs in islet xenotransplantation: a tool for gaining further insights in the mechanisms of the rejection process.
Transplantation 2002;74(8):1084-9.
2002: Mats Engstrand; Cecilia Johnsson; Erik Larsson; Gunnar Tufveson; Olle Korsgren
Quantification of lymphocytes propagating from rat-kidney allografts--a tool to monitor anti-rejection treatment.
Transplant immunology 2002;10(1):31-6.
2002: Lisa Ozmen; Kristina Nilsson Ekdahl; Graciela Elgue; Rolf Larsson; Olle Korsgren; Bo Nilsson
Inhibition of thrombin abrogates the instant blood-mediated inflammatory reaction triggered by isolated human islets: possible application of the thrombin inhibitor melagatran in clinical islet transplantation.
Diabetes 2002;51(6):1779-84.
2002: Birgitta Benda; Hans-Gustaf Ljunggren; Robert Peach; Jan-Olov Sandberg; Olle Korsgren
Co-stimulatory molecules in islet xenotransplantation: CTLA4Ig treatment in CD40 ligand-deficient mice.
Cell transplantation 2002;11(7):715-20.
2002: Henrik Krook; Anette Hagberg; Zhenshun Song; Ulf Landegren; Lars Wennberg; Olle Korsgren
A distinct Th1 immune response precedes the described Th2 response in islet xenograft rejection.
Diabetes 2002;51(1):79-86.
2001: Guosheng Wu; Olle Korsgren; Nico van Rooijen; Annika Tibell
Suppression of T cells results in long-term survival of mouse heart xenografts in C6-deficient rats.
Xenotransplantation 2001;8(4):303-9.
2001: Angelica Loskog; A Björkland; M P Brown; Olle Korsgren; Per-Uno Malmstrom; Thomas H Tötterman
Potent antitumor effects of CD154 transduced tumor cells in experimental bladder cancer.
The Journal of urology 2001;166(3):1093-7.
2001: W Bennet; B Sundberg; Graciela Elgue; Rolf Larsson; Olle Korsgren; Bo Nilsson
A new in vitro model for the study of pig-to-human vascular hyperacute rejection.
Xenotransplantation 2001;8(3):176-84.
2001: W Bennet; A Björkland; B Sundberg; D Brandhorst; MD Brendel; A Richards; DJ White; Bo Nilsson; Carl G Groth; Olle Korsgren
Expression of complement regulatory proteins on islets of Langerhans: a comparison between human islets and islets isolated from normal and hDAF transgenic pigs.
Transplantation 2001;72(2):312-9.
2001: KJ Rydgård; Zhensung Song; Aksel Foss; Gunnar Tufveson; Lars Wennberg; Torbjörn Lundgren; Annika Tibell; Carl G Groth; Olle Korsgren
Procurement of human pancreases for islet isolation-the initiation of a Scandinavian collaborative network.
Transplantation proceedings 2001;33(4):2538.
2001: Lars Wennberg; Zhensung Song; KJ Rydgård; W Bennet; S Nava; Torbjörn Lundgren; B Sundberg; Carl G Groth; Olle Korsgren
Experience with 450 adult porcine islet isolation procedures.
Transplantation proceedings 2001;33(4):2537.
2001: Annika Tibell; Jan Bolinder; Eva Hagström-Toft; J Tollemar; Mathias D Brendel; Michael Eckhard; Daniel Brandhorst; Reinhard Bretzel; Olle Korsgren; Carl G Groth
Experience with human islet transplantation in Sweden.
Transplantation proceedings 2001;33(4):2535-6.
2001: Lars Wennberg; Zhensung Song; W Bennet; J Zhang; S Nava; B Sundberg; S Bari; Carl G Groth; Olle Korsgren
Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine A, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days.
Transplantation 2001;71(8):1024-33.
2001: Lars Wennberg; B Sundberg; K Ekdahl-Nilsson; Olle Korsgren
C-Peptide determinations in islet xenotransplantation: A study in the pig-to-mouse model.
Cell transplantation 2001;10(2):165-73.
2001: Torbjörn Lundgren; W Bennet; Annika Tibell; Johan Söderlund; B Sundberg; Z Song; Graciela Elgue; R Harrison; A Richards; DJ White; Bo Nilsson; Carl G Groth; Olle Korsgren
Soluble complement receptor 1 (TP10) preserves adult porcine islet morphology after intraportal transplantation into cynomolgus monkeys.
Transplantation proceedings 2001;33(1-2):725.
2001: Guosheng S Wu; S Petersson; A K Spiik; Olle Korsgren; Annika Tibell
Antisense NF-kappaB p65 prolongs experimental allo- and xenograft survival.
Transplantation proceedings 2001;33(1-2):360.
2001: Olle Korsgren; Leif Jansson; E Ekblad; F Sundler
Reinnervation of syngeneic pancreatico-duodenal grafts in rats.
Transplantation 2001;71(1):8-13.
2001: Birgitta Benda; Olle Korsgren
Interleukin-6 in islet xenograft rejection.
Transplant international : official journal of the European Society for Organ Transplantation 2001;14(2):63-71.
2000: Guosheng Wu; Olle Korsgren; J Zhang; Z Song; Nico van Rooijen; Annika Tibell
Pig islet xenograft rejection is markedly delayed in macrophage-depleted mice: a study in streptozotocin diabetic animals.
Xenotransplantation 2000;7(3):214-20.
2000: Birgitta Benda; N Lycke; Maria Holstad; Olle Korsgren
Delayed type hypersensitivity-associated cytokines in islet xenotransplantation: limited efficacy of interleukin-2- and tumor necrosis factor-alpha-blockade in interferon-gamma receptor-deficient mice.
Xenotransplantation 2000;7(3):206-13.
2000: Guosheng S Wu; Olle Korsgren; J G Zhang; Z S Song; Nico van Rooijen; Annika Tibell
Role of macrophages and natural killer cells in the rejection of pig islet xenografts in mice.
Transplantation proceedings 2000;32(5):1069.
2000: W Bennet; B Sundberg; Graciela Elgue; MD Brendel; A Richards; DJ White; Carl G Groth; Olle Korsgren
Complement regulatory proteins on human and porcine nontransgenic and hDAF transgenic islet cells: expression and role in susceptibility to lysis by human serum.
Transplantation proceedings 2000;32(5):1066.
2000: W Bennet; B Sundberg; Zhensung Song; Graciela Elgue; Lars Wennberg; A Richards; DJ White; Rolf Larsson; Bo Nilsson; Carl G Groth; Olle Korsgren
Porcine islets of langerhans isolated from normal and hDAF transgenic pigs elicit the same acute inflammatory reaction during exposure to human blood; inhibition of the response with soluble complement receptor 1 and heparin.
Transplantation proceedings 2000;32(5):1065.
2000: Lars Wennberg; Zhensung Song; J Zhang; W Bennet; S Nava; S Bari; B Sundberg; Olle Korsgren; Carl G Groth
Diabetic rats transplanted with adult porcine islets and immunosuppressed with cyclosporine, mycophenolate mofetil, and leflunomide remain normoglycemic for up to 100 days.
Transplantation proceedings 2000;32(5):1061.
2000: Lars Wennberg; Zhensung Song; M Wijkström; J Zhang; S Bari; B Sundberg; Carl G Groth; Olle Korsgren
Brequinar in combination with cyclosporine a inhibits islet xenograft rejection for up to 24 days: a study in the pig-to-rat model.
Transplantation proceedings 2000;32(5):1026.
2000: Zhensung Song; Lars Wennberg; J Zhang; B Sundberg; S Bari; Carl G Groth; Olle Korsgren
Protective effect of FK-506 in pig-to-rat islet xenotransplantation is abrogated by prednisolone.
Transplantation proceedings 2000;32(5):1025.
2000: M Wijkström; Zhensung Song; J Zhang; S Bari; B Sundberg; Carl G Groth; Olle Korsgren; Lars Wennberg
Efficacy of malononitriloamide 279 and 715 in islet xenotransplantation: a study in the pig-to-rat model.
Transplantation proceedings 2000;32(5):1024.
2000: J Zhang; Zhensung Song; M Wijkström; S Bari; B Sundberg; S Nava; Carl G Groth; Olle Korsgren; Lars Wennberg
FTY720 in combination with CsA inhibits islet xenograft rejection: a study in the pig-to-rat model.
Transplantation proceedings 2000;32(5):1017.
2000: Guosheng S Wu; Olle Korsgren; Annika Tibell
Cyclosporine induces long-term xenograft survival in the mouse-to-C6-deficient rat heart transplantation model.
Transplantation proceedings 2000;32(5):1015.
2000: Mats Engstrand; C Tournay; Marie-Alix Peyrat; Britt-Marie Eriksson; Jonas Wadström; Benita Zweygberg Wirgart; François Romagné; Marc Bonneville; Thomas H Tötterman; Olle Korsgren
Characterization of CMVpp65-specific CD8+ T lymphocytes using MHC tetramers in kidney transplant patients and healthy participants.
Transplantation 2000;69(11):2243-50.
2000: W Bennet; A Björkland; B Sundberg; H Davies; J Liu; Jan Holgersson; Olle Korsgren
A comparison of fetal and adult porcine islets with regard to Gal alpha (1,3)Gal expression and the role of human immunoglobulins and complement in islet cell cytotoxicity.
Transplantation 2000;69(8):1711-7.
2000: W Bennet; B Sundberg; Torbjörn Lundgren; Annika Tibell; Carl G Groth; A Richards; DJ White; Graciela Elgue; Rolf Larsson; Bo Nilsson; Olle Korsgren
Damage to porcine islets of Langerhans after exposure to human blood in vitro, or after intraportal transplantation to cynomologus monkeys: protective effects of sCR1 and heparin.
Transplantation 2000;69(5):711-9.
2000: Carl G Groth; Annika Tibell; Lars Wennberg; W Bennet; Torbjörn Lundgren; KJ Rydgård; S Lundin; Ellinor Lindeborg; Olle Korsgren
Clinical aspects and perspectives in islet xenotransplantation.
Journal of hepato-biliary-pancreatic surgery 2000;7(4):364-9.
2000: W Bennet; Carl G Groth; Rolf Larsson; Bo Nilsson; Olle Korsgren
Isolated human islets trigger an instant blood mediated inflammatory reaction: implications for intraportal islet transplantation as a treatment for patients with type 1 diabetes.
Upsala journal of medical sciences 2000;105(2):125-33.
1999: Olle Korsgren; Rolf Christofferson; Leif Jansson
Angiogenesis and angioarchitecture of transplanted fetal porcine islet-like cell clusters.
Transplantation 1999;68(11):1761-6.
1999: Timo Otonkoski; Jarkko Ustinov; Suvi Rasilainen; Erkki A Kallio; Olle Korsgren; Pekka Häyry
Differentiation and maturation of porcine fetal islet cells in vitro and after transplantation.
Transplantation 1999;68(11):1674-83.
1999: Mats Engstrand; Cecilia Johnsson; Olle Korsgren; Gunnar Tufveson
Ex vivo propagation and characterization of lymphocytes from rejecting rat-kidney allografts.
Transplant immunology 1999;7(4):189-96.
1999: Olle Korsgren; Arne Wallgren; M Satake; Alex Karlsson-Parra
Xenograft rejection of fetal porcine islet-like cell clusters in the rat: effects of active and passive immunization.
Xenotransplantation 1999;6(4):271-80.
1999: Guosheng Wu; Olle Korsgren; Nico van Rooijen; Lars Wennberg; Annika Tibell
The effect of macrophage depletion on delayed xenograft rejection: studies in the guinea pig-to-C6-deficient rat heart transplantation model.
Xenotransplantation 1999;6(4):262-70.
1999: Lena C Larsson; Kimberly Ann Czech; Håkan Widner; Olle Korsgren
Discordant neural tissue xenografts survive longer in immunoglobulin deficient mice.
Transplantation 1999;68(8):1153-60.
1999: W Bennet; B Sundberg; Carl G Groth; MD Brendel; D Brandhorst; Heide Brandhorst; R G Bretzel; Graciela Elgue; Rolf Larsson; Bo Nilsson; Olle Korsgren
Incompatibility between human blood and isolated islets of Langerhans: a finding with implications for clinical intraportal islet transplantation?
Diabetes 1999;48(10):1907-14.
1999: Johan Söderlund; Lars Wennberg; Esmeralda Castaños-Velez; Peter Biberfeld; S Zhu; Annika Tibell; Carl G Groth; Olle Korsgren
Fetal porcine islet-like cell clusters transplanted to cynomolgus monkeys: an immunohistochemical study.
Transplantation 1999;67(6):784-91.
1999: Zhensung Song; Lars Wennberg; W Bennet; B Sundberg; Carl G Groth; Olle Korsgren
FK 506 prevents islet xenograft rejection: a study in the pig-to-rat model.
Transplantation proceedings 1999;31(1-2):981.
1999: Guosheng S Wu; Olle Korsgren; Lars Wennberg; Annika Tibell
Deoxyspergualin delays xenograft rejection in the guinea pig-to-C6-deficient rat heart transplantation model.
Transplant international : official journal of the European Society for Organ Transplantation 1999;12(6):415-22.
1999: Carl G Groth; Annika Tibell; Lars Wennberg; Olle Korsgren
Xenoislet transplantation: experimental and clinical aspects.
Journal of molecular medicine (Berlin, Germany) 1999;77(1):153-4.
1998: J Topp; Olle Korsgren; N Welsh; Leif Jansson
Evidence of a negative feedback system regulating the total beta-cell volume in nondiabetic rats that received pancreas transplants.
Transplantation 1998;66(10):1392-4.
1998: Carl G Groth; Olle Korsgren; Lars Wennberg; Zhensung Song; G Wu; F Reinholt; Annika Tibell
Pig-to-human islet transplantation.
Transplantation proceedings 1998;30(7):3809-10.
1998: Birgitta Benda; Jan-Olov Sandberg; Maria Holstad; Olle Korsgren
T cells in islet-like cell cluster xenograft rejection: a study in the pig-to-mouse model.
Transplantation 1998;66(4):435-40.
1998: Birgitta Benda; Olle Korsgren
Xenograft rejection of fetal porcine islet-like cell clusters in normal, T-cell receptor beta-, delta-, beta x delta-; perforin-; or granzyme B-deficient mice.
Transplantation proceedings 1998;30(2):586.
1997: Jan-Olov Sandberg; Olle Korsgren
Islet allo- and xenotransplantation in normal, intercellular adhesion molecule-1-deficient, and P selectin-deficient mice.
Transplantation 1997;64(4):584-9.
1997: Lars Wennberg; Carl G Groth; Annika Tibell; S Zhu; J Liu; Ehab Rafael; Johan Söderlund; Peter Biberfeld; R E Morris; A Karlsson-Parra; Olle Korsgren
Triple drug treatment with cyclosporine, leflunomide and mycophenolate mofetil prevents rejection of pig islets transplanted into rats and primates.
Transplantation proceedings 1997;29(5):2498.
1997: Jan-Olov Sandberg; Birgitta Benda; N Lycke; Olle Korsgren
Xenograft rejection of porcine islet-like cell clusters in normal, interferon-gamma, and interferon-gamma receptor deficient mice.
Transplantation 1997;63(10):1446-52.
1997: Lars Wennberg; A Karlsson-Parra; B Sundberg; Ehab Rafael; J Liu; S Zhu; Carl G Groth; Olle Korsgren
Efficacy of immunosuppressive drugs in islet xenotransplantation: leflunomide in combination with cyclosporine and mycophenolate mofetil prevents islet xenograft rejection in the pig-to-rat model.
Transplantation 1997;63(9):1234-42.
1997: Agneta Lukinius; Olle Korsgren; Lars Grimelius; Erik Wilander
Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells.
Endocrinology 1997;138(4):5319-25.
1997: Birgitta Benda; Olle Korsgren
Transfer of immunocompetent cells to athymic nude mice previously transplanted with fetal porcine islet-like cell clusters.
Transplantation proceedings 1997;29(1-2):930.
1996: Carl G Groth; Annika Tibell; Lars Wennberg; Olle Korsgren
Experimental and clinical experience with xenoislet transplantation.
Transplantation proceedings 1996;28(6):3515.
1996: Agneta Lukinius; Olle Korsgren; Lars Grimelius; E Wilander
Expression of islet amyloid polypeptide in fetal and adult porcine and human pancreatic islet cells.
Endocrinology 1996;137(12):5319-25.
1996: Birgitta Benda; A Karlsson-Parra; A Ridderstad; Olle Korsgren
Xenograft rejection of porcine islet-like cell clusters in immunoglobulin- or Fc-receptor gamma-deficient mice.
Transplantation 1996;62(9):1207-11.
1996: Olle Korsgren; Leif Jansson; F Sundler
Reinnervation of transplanted fetal porcine endocrine pancreas. Evidence for initial growth and subsequent degeneration of nerve fibers in the islet grafts.
Transplantation 1996;62(3):352-7.
1996: A Karlsson-Parra; A Ridderstad; A C Wallgren; E Möller; H G Ljunggren; Olle Korsgren
Xenograft rejection of porcine islet-like cell clusters in normal and natural killer cell-depleted mice.
Transplantation 1996;61(9):1313-20.
1996: Lars Wennberg; A C Wallgren; B Sundberg; Ehab Rafael; S Zhu; J Liu; Annika Tibell; A Karlsson-Parra; Carl G Groth; Olle Korsgren
Immunosuppression with cyclosporin A in combination with leflunomide and mycophenolate mofetil prevents rejection of pig-islets transplanted into rats.
Transplantation proceedings 1996;28(2):819.
1996: Carl G Groth; Olle Korsgren; Lars Wennberg; Annika Tibell; S Zhu; B Sundberg; Johan Söderlund; Peter Biberfeld; M Satake; E Möller; A C Wallgren; A Karlsson-Parra
Xenoislet rejection following pig-to-rat, pig-to-primate, and pig-to-man transplantation.
Transplantation proceedings 1996;28(2):538-9.
1995: Lars Wennberg; A C Wallgren; B Sundberg; Ehab Rafael; S Zhu; J Liu; Annika Tibell; A Karlsson-Parra; Carl G Groth; Olle Korsgren
Immunosuppression with leflunomide and cyclosporine prevents pig-to-rat islet xenograft rejection.
Transplantation proceedings 1995;27(6):3314-5.
1995: A C Wallgren; A Karlsson-Parra; Olle Korsgren
The main infiltrating cell in xenograft rejection is a CD4+ macrophage and not a T lymphocyte.
Transplantation 1995;60(6):594-601.
1995: Jan-Olov Sandberg; B Margulis; Leif Jansson; Rolf Karlsten; Olle Korsgren
Transplantation of fetal porcine pancreas to diabetic or normoglycemic nude mice. Evidence of a rapid engraftment process demonstrated by blood flow and heat shock protein 70 measurements.
Transplantation 1995;59(12):1665-9.
1995: Olle Korsgren; A Wallgren; A Ridderstad; M Satake; E Möller; A Karlsson-Parra
The CD4+ effector cell in islet xenotransplantation is a macrophage and not a T-lymphocyte.
Transplantation proceedings 1995;27(1):251.
1995: Lars Wennberg; A C Wallgren; A Karlsson-Parra; Tomasz Kozlowski; B Sundberg; Annika Tibell; Carl G Groth; Olle Korsgren
Efficacy of various immunosuppressive drugs in preventing pig-to-rat islet xenograft rejection.
Transplantation proceedings 1995;27(1):266-7.
1995: Agneta Lukinius; Leif Jansson; Olle Korsgren
Ultrastructural evidence for blood microvessels devoid of an endothelial cell lining in transplanted pancreatic islets.
The American journal of pathology 1995;146(2):429-35.
1994: Carl G Groth; Olle Korsgren; Annika Tibell; J Tollemar; E Möller; Jan Bolinder; J Ostman; F P Reinholt; C Hellerström; A Andersson
Transplantation of porcine fetal pancreas to diabetic patients.
Lancet 1994;344(8934):1402-4.
1994: M Satake; Olle Korsgren; A Ridderstad; A Karlsson-Parra; A C Wallgren; E Möller
Immunological characteristics of islet cell xenotransplantation in humans and rodents.
Immunological reviews 1994;141():191-211.
1994: M Satake; N Kawagishi; M Kumagai-Braesch; B E Samuelsson; L Rydberg; Annika Tibell; A Andersson; Olle Korsgren; Carl G Groth; E Möller
Specificity of human xenoantibodies formed in response to fetal porcine isletlike cell clusters.
Transplantation proceedings 1994;26(3):1122.
1994: Annika Tibell; F P Reinholt; Olle Korsgren; A Andersson; C Hellerström; E Möller; Carl G Groth
Morphologic identification of porcine islet cells three weeks after transplantation into a diabetic patient.
Transplantation proceedings 1994;26(3):1121.
1994: Lars Wennberg; B Sundberg; Olle Korsgren; Carl G Groth
Validity of urinary C-peptide determinations in xenogeneic islet transplantation.
Transplantation proceedings 1994;26(3):1105.
1994: Olle Korsgren; Leif Jansson
Discordant cellular xenografts revascularized in intermediate athymic hosts fail to induce a hyperacute rejection when transplanted to immunocompetent rats.
Transplantation 1994;57(9):1408-11.
1994: Annika Tibell; Carl G Groth; E Möller; Olle Korsgren; A Andersson; C Hellerström
Pig-to-human islet transplantation in eight patients.
Transplantation proceedings 1994;26(2):762-3.
1994: Olle Korsgren; Leif Jansson
Characterization of mixed syngeneic-allogeneic and syngeneic-xenogeneic islet-graft rejections in mice. Evidence of functional impairment of the remaining syngeneic islets in xenograft rejections.
The Journal of clinical investigation 1994;93(3):1113-9.
1994: Olle Korsgren; Leif Jansson
Porcine islet-like cell clusters cure diabetic nude rats when transplanted under the kidney capsule, but not when implanted into the liver or spleen.
Cell transplantation 1994;3(1):49-54.
1994: Leif Jansson; Olle Korsgren
Washout kinetics of blood cells from the perfused pancreas of normoglycemic and diabetic rats.
Upsala journal of medical sciences 1994;99(2):139-45.
1993: Jan-Olov Sandberg; Olle Korsgren; Carl G Groth; A Andersson
15-Deoxyspergualin prolongs pancreatic islet allo- and xenograft survival in mice.
Pharmacology & toxicology 1993;73(1):24-8.
1993: Olle Korsgren; Leif Jansson; A Andersson; F Sundler
Reinnervation of transplanted pancreatic islets. A comparison among islets implanted into the kidney, spleen, and liver.
Transplantation 1993;56(1):138-43.
1993: Leif Jansson; Olle Korsgren; J Wahlberg; A Andersson
Effects of cyclosporin A on the blood flow of the native and transplanted rat pancreas and duodenum.
Transplant international : official journal of the European Society for Organ Transplantation 1993;6(3):143-7.
1993: Carl G Groth; A Andersson; Olle Korsgren; Annika Tibell; J Tollemar; M Kumagai-Braesch; E Möller; Jan Bolinder; J Ostman; A Bjöersdorff
Transplantation of porcine fetal islet-like cell clusters into eight diabetic patients.
Transplantation proceedings 1993;25(1 Pt 2):970.
1993: Olle Korsgren; Leif Jansson; E Möller; Carl G Groth
Pancreatic islet transplantation in the human.
Advances in nephrology from the Necker Hospital 1993;22():371-86.
1993: Olle Korsgren; A Andersson; Stellan Sandler
In vitro screening of putative compounds inducing fetal porcine pancreatic beta-cell differentiation: implications for cell transplantation in insulin-dependent diabetes mellitus.
Upsala journal of medical sciences 1993;98(1):39-52.
1992: Agneta Lukinius; J L Ericsson; Lars Grimelius; Olle Korsgren
Ultrastructural studies of the ontogeny of fetal human and porcine endocrine pancreas, with special reference to colocalization of the four major islet hormones.
Developmental biology 1992;153(2):376-85.
1992: Stellan Sandler; Leif Jansson; Olle Korsgren; A Andersson; Claes Hellerström
Engraftment of isolated islets after syngeneic transplantation into normal and diabetic mice.
Transplantation proceedings 1992;24(3):983-4.
1992: Carl G Groth; Olle Korsgren; A Andersson; C Hellerström; A Bjöersdorff; Annika Tibell; J Tollemar; Jan Bolinder; J Ostman; M Kumagai
Evidence of xenograft function in a diabetic patient grafted with porcine fetal pancreas.
Transplantation proceedings 1992;24(3):972-3.
1992: Leif Jansson; Olle Korsgren; J Wahlberg; A Andersson
Whole pancreatic and islet blood flow after syngeneic pancreaticoduodenal transplantation in the rat.
Transplantation proceedings 1992;24(3):877-8.
1992: Olle Korsgren; Leif Jansson; A Andersson; F Sundler
Reinnervation of transplanted pancreatic islets: a comparison between islets implanted into the kidney, spleen, or liver.
Transplantation proceedings 1992;24(3):1025-6.
1992: M Kumagai Braesch; Carl G Groth; Olle Korsgren; A Andersson; C Hellerström; A Bjöersdorff; Annika Tibell; J Tollemar; Jan Bolinder; J Ostman
Immune response of diabetic patients against transplanted porcine fetal islet cells.
Transplantation proceedings 1992;24(2):679-80.
1992: A Andersson; Carl G Groth; Olle Korsgren; Annika Tibell; J Tollemar; M Kumagai; E Möller; Jan Bolinder; J Ostman; A Bjöersdorff
Transplantation of porcine fetal islet-like cell clusters to three diabetic patients.
Transplantation proceedings 1992;24(2):677-8.
1992: A Bjöersdorff; Olle Korsgren; A Andersson; J Tollemar; A S Malmborg; C G Ehrnst Groth
Microbiologic screening as a preparatory step for clinical xenografting of porcine fetal islet-like cell clusters.
Transplantation proceedings 1992;24(2):674-6.
1992: J Tollemar; Carl G Groth; Olle Korsgren; A Andersson; M Blombäck; P Olsson
Transplantation of discordant xenogeneic endocrine pancreatic cell clusters into the liver: effects on coagulation, liver function, and hepatic hemodynamics. A safety study in the pig to dog model.
Transplantation proceedings 1992;24(2):665-6.
1992: Leif Jansson; Olle Korsgren; J Wahlberg; A Andersson
Pancreatic islet blood flow after syngeneic pancreaticoduodenal transplantation in rats. Differences between the blood perfusion of the native and the transplanted gland.
Transplantation 1992;53(3):517-21.
1992: Olle Korsgren; Carl G Groth; A Andersson; Claes Hellerström; Annika Tibell; J Tollemar; Jan Bolinder; J Ostman; M Kumagai; E Möller
Transplantation of porcine fetal pancreas to a diabetic patient.
Transplantation proceedings 1992;24(1):352-3.
1992: Olle Korsgren; A Andersson; Leif Jansson; F Sundler
Reinnervation of syngeneic mouse pancreatic islets transplanted into renal subcapsular space.
Diabetes 1992;41(2):130-5.
1992: J Tollemar; Carl G Groth; Olle Korsgren; A Andersson; M Blombäck; P Olsson
Injection of xenogeneic endocrine pancreatic tissue into the portal vein--effects on coagulation, liver function, and hepatic hemodynamics. A study in the pig-to-dog model.
Transplantation 1992;53(1):139-42.
1991: Olle Korsgren; Leif Jansson; Decio L Eizirik; A Andersson
Functional and morphological differentiation of fetal porcine islet-like cell clusters after transplantation into nude mice.
Diabetologia 1991;34(6):379-86.
1991: Olle Korsgren; A Andersson; Leif Jansson; F Sundler
Reinnervation of transplanted mouse pancreatic islets.
Transplantation proceedings 1991;23(1 Pt 1):750-1.
1991: C Hellerström; Decio L Eizirik; Nils Welsh; A Sjöholm; Leif Jansson; C Svensson; E Strandell; Olle Korsgren; Z Q Li; A Andersson
New perspectives on the structure and function of the normal and diabetic beta-cell.
Upsala journal of medical sciences 1991;96(1):1-16.
1990: Olle Korsgren; Leif Jansson; Stellan Sandler; A Andersson
Hyperglycemia-induced B cell toxicity. The fate of pancreatic islets transplanted into diabetic mice is dependent on their genetic background.
The Journal of clinical investigation 1990;86(6):2161-8.
1990: Olle Korsgren; Leif Jansson; A Andersson
Functional maturation of fetal porcine isletlike cell clusters after transplantation into nude mice.
Transplantation proceedings 1990;22(2):832-3.
1990: A Dunger; Olle Korsgren; A Andersson
DNA replication in mouse pancreatic islets transplanted subcapsularly into the kidney or intraportally into the liver. Influence of unilateral nephrectomy or partial hepatectomy.
Transplantation 1990;49(4):686-9.
1990: Leif Jansson; Olle Korsgren; Stellan Sandler; A Andersson
Influence of persistent hyperglycemia on transplanted pancreatic islets.
Hormone and metabolic research. Supplement series 1990;25():137-42.
1989: Decio L Eizirik; Stellan Sandler; Olle Korsgren; Leif Jansson; A Andersson
Persistent impairment of the insulin response to glucose both in vivo and in vitro after streptozotocin exposure: studies with grafted pancreatic islets and islets maintained in culture.
Acta endocrinologica 1989;121(6):849-56.
1989: A Andersson; Olle Korsgren; P Naeser
DNA replication in transplanted and endogenous pancreatic islets of obese-hyperglycemic mice at different stages of the syndrome.
Metabolism: clinical and experimental 1989;38(10):974-8.
1989: Olle Korsgren; Leif Jansson; A Andersson
Effects of hyperglycemia on function of isolated mouse pancreatic islets transplanted under kidney capsule.
Diabetes 1989;38(4):510-5.
1989: Olle Korsgren; Stellan Sandler; Leif Jansson; Carl G Groth; Claes Hellerström; A Andersson
Effects of culture conditions on formation and hormone content of fetal porcine isletlike cell clusters.
Diabetes 1989;38 Suppl 1():209-12.
1989: Stellan Sandler; A Andersson; Olle Korsgren; J Tollemar; B Petersson; Carl G Groth; Claes Hellerström
Tissue culture of human fetal pancreas. Effects of nicotinamide on insulin production and formation of isletlike cell clusters.
Diabetes 1989;38 Suppl 1():168-71.
1989: A Andersson; Olle Korsgren; Leif Jansson
Intraportally transplanted pancreatic islets revascularized from hepatic arterial system.
Diabetes 1989;38 Suppl 1():192-5.
1988: Claes Hellerström; A Andersson; Carl G Groth; Stellan Sandler; Leif Jansson; Olle Korsgren; I Swenne; B Petersson; J Tollemar; G Tydén
Experimental pancreatic transplantation in diabetes.
Diabetes care 1988;11 Suppl 1():45-53.
1988: E Strandell; Decio L Eizirik; Olle Korsgren; Stellan Sandler
Functional characteristics of cultured mouse pancreatic islets following exposure to different streptozotocin concentrations.
Molecular and cellular endocrinology 1988;59(1-2):83-91.
1988: Olle Korsgren; Stellan Sandler; A S Landström; Leif Jansson; A Andersson
Large-scale production of fetal porcine pancreatic isletlike cell clusters. An experimental tool for studies of islet cell differentiation and xenotransplantation.
Transplantation 1988;45(3):509-14.
1987: Stellan Sandler; A Andersson; Olle Korsgren; J Tollemar; B Petersson; Carl G Groth; Claes Hellerström
Tissue culture of human fetal pancreas: growth hormone stimulates the formation and insulin production of islet-like cell clusters.
The Journal of clinical endocrinology and metabolism 1987;65(6):1154-8.