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Stanley Korsmeyer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Ren Decheng; Kim Hyungjin; Tu Ho-Chou; Westergard Todd D; Fisher Jill K; Rubens Jeff A; Korsmeyer Stanley J; Hsieh James J-D; Cheng Emily H-Y
The VDAC2-BAK rheostat controls thymocyte survival.
Danial Nika N; Walensky Loren D; Zhang Chen-Yu; Choi Cheol Soo; Fisher Jill K; Molina Anthony J A; Datta Sandeep Robert; Pitter Kenneth L; Bird Gregory H; Wikstrom Jakob D; Deeney Jude T; Robertson Kirsten; Morash Joel; Kulkarni Ameya; Neschen Susanne; Kim Sheene; Greenberg Michael E; Corkey Barbara E; Shirihai Orian S; Shulman Gerald I; Lowell Bradford B; Korsmeyer Stanley J
Dual role of proapoptotic BAD in insulin secretion and beta cell survival.
Woodland Robert T; Fox Casey J; Schmidt Madelyn R; Hammerman Peter S; Opferman Joseph T; Korsmeyer Stanley J; Hilbert David M; Thompson Craig B
Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.

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All Publications

2009: Ren Decheng; Kim Hyungjin; Tu Ho-Chou; Westergard Todd D; Fisher Jill K; Rubens Jeff A; Korsmeyer Stanley J; Hsieh James J-D; Cheng Emily H-Y
The VDAC2-BAK rheostat controls thymocyte survival.
Science signaling 2009;2(85):ra48.
2008: Danial Nika N; Walensky Loren D; Zhang Chen-Yu; Choi Cheol Soo; Fisher Jill K; Molina Anthony J A; Datta Sandeep Robert; Pitter Kenneth L; Bird Gregory H; Wikstrom Jakob D; Deeney Jude T; Robertson Kirsten; Morash Joel; Kulkarni Ameya; Neschen Susanne; Kim Sheene; Greenberg Michael E; Corkey Barbara E; Shirihai Orian S; Shulman Gerald I; Lowell Bradford B; Korsmeyer Stanley J
Dual role of proapoptotic BAD in insulin secretion and beta cell survival.
Nature medicine 2008;14(2):144-53.
2008: Woodland Robert T; Fox Casey J; Schmidt Madelyn R; Hammerman Peter S; Opferman Joseph T; Korsmeyer Stanley J; Hilbert David M; Thompson Craig B
Multiple signaling pathways promote B lymphocyte stimulator dependent B-cell growth and survival.
Blood 2008;111(2):750-60.
2007: Kirsch David G; Dinulescu Daniela M; Miller John B; Grimm Jan; Santiago Philip M; Young Nathan P; Nielsen G Petur; Quade Bradley J; Chaber Christopher J; Schultz Christian P; Takeuchi Osamu; Bronson Roderick T; Crowley Denise; Korsmeyer Stanley J; Yoon Sam S; Hornicek Francis J; Weissleder Ralph; Jacks Tyler
A spatially and temporally restricted mouse model of soft tissue sarcoma.
Nature medicine 2007;13(8):992-7.
2007: Ruiz-Vela Antonio; Korsmeyer Stanley J
Proapoptotic histone H1.2 induces CASP-3 and -7 activation by forming a protein complex with CYT c, APAF-1 and CASP-9.
FEBS letters 2007;581(18):3422-8.
2007: Bernal Federico; Tyler Andrew F; Korsmeyer Stanley J; Walensky Loren D; Verdine Gregory L
Reactivation of the p53 tumor suppressor pathway by a stapled p53 peptide.
Journal of the American Chemical Society 2007;129(9):2456-7.
2007: Kim Se Young; Levenson Jonathan M; Korsmeyer Stanley; Sweatt J David; Schumacher Armin
Developmental regulation of Eed complex composition governs a switch in global histone modification in brain.
The Journal of biological chemistry 2007;282(13):9962-72.
2006: Oh Kyoung Joon; Barbuto Scott; Pitter Kenneth; Morash Joel; Walensky Loren D; Korsmeyer Stanley J
A membrane-targeted BID BCL-2 homology 3 peptide is sufficient for high potency activation of BAX in vitro.
The Journal of biological chemistry 2006;281(48):36999-7008.
2006: Walensky Loren D; Pitter Kenneth; Morash Joel; Oh Kyoung Joon; Barbuto Scott; Fisher Jill; Smith Eric; Verdine Gregory L; Korsmeyer Stanley J
A stapled BID BH3 helix directly binds and activates BAX.
Molecular cell 2006;24(2):199-210.
2006: Takeda Shugaku; Chen David Y; Westergard Todd D; Fisher Jill K; Rubens Jeffrey A; Sasagawa Satoru; Kan Jason T; Korsmeyer Stanley J; Cheng Emily H-Y; Hsieh James J-D
Proteolysis of MLL family proteins is essential for taspase1-orchestrated cell cycle progression.
Genes & development 2006;20(17):2397-409.
2006: Lin Stephen S; Bassik Michael C; Suh Heikyung; Nishino Mari; Arroyo Jason D; Hahn William C; Korsmeyer Stanley J; Roberts Thomas M
PP2A regulates BCL-2 phosphorylation and proteasome-mediated degradation at the endoplasmic reticulum.
The Journal of biological chemistry 2006;281(32):23003-12.
2006: Certo Michael; Del Gaizo Moore Victoria; Nishino Mari; Wei Guo; Korsmeyer Stanley; Armstrong Scott A; Letai Anthony
Mitochondria primed by death signals determine cellular addiction to antiapoptotic BCL-2 family members.
Cancer cell 2006;9(5):351-65.
2006: Bermpohl Daniela; You Zerong; Korsmeyer Stanley J; Moskowitz Michael A; Whalen Michael J
Traumatic brain injury in mice deficient in Bid: effects on histopathology and functional outcome.
Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism 2006;26(5):625-33.
2006: Hetz Claudio; Bernasconi Paula; Fisher Jill; Lee Ann-Hwee; Bassik Michael C; Antonsson Bruno; Brandt Gabriel S; Iwakoshi Neal N; Schinzel Anna; Glimcher Laurie H; Korsmeyer Stanley J
Proapoptotic BAX and BAK modulate the unfolded protein response by a direct interaction with IRE1alpha.
Science (New York, N.Y.) 2006;312(5773):572-6.
2006: Zhou Huiqing; Spicuglia Salvatore; Hsieh James J-D; Mitsiou Dimitra J; Høiby Torill; Veenstra Gert Jan C; Korsmeyer Stanley J; Stunnenberg Hendrik G
Uncleaved TFIIA is a substrate for taspase 1 and active in transcription.
Molecular and cellular biology 2006;26(7):2728-35.
2005: Hetz Claudio; Vitte Pierre-Alain; Bombrun Agnes; Rostovtseva Tatiana K; Montessuit Sylvie; Hiver Agnes; Schwarz Matthias K; Church Dennis J; Korsmeyer Stanley J; Martinou Jean-Claude; Antonsson Bruno
Bax channel inhibitors prevent mitochondrion-mediated apoptosis and protect neurons in a model of global brain ischemia.
The Journal of biological chemistry 2005;280(52):42960-70.
2005: Nakatani Yoshihiro; Konishi Hiroaki; Vassilev Alex; Kurooka Hisanori; Ishiguro Keiichiro; Sawada Jun-ichi; Ikura Tsuyoshi; Korsmeyer Stanley J; Qin Jun; Herlitz Anna M
p600, a unique protein required for membrane morphogenesis and cell survival.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(42):15093-8.
2005: Zinkel Sandra S; Hurov Kristen E; Ong Christy; Abtahi Farvardean M; Gross Atan; Korsmeyer Stanley J
A role for proapoptotic BID in the DNA-damage response.
Cell 2005;122(4):579-91.
2005: Schinzel Anna C; Takeuchi Osamu; Huang Zhihong; Fisher Jill K; Zhou Zhipeng; Rubens Jeffery; Hetz Claudio; Danial Nika N; Moskowitz Michael A; Korsmeyer Stanley J
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(34):12005-10.
2005: Takeuchi Osamu; Fisher Jill; Suh Heikyung; Harada Hisashi; Malynn Barbara A; Korsmeyer Stanley J
Essential role of BAX,BAK in B cell homeostasis and prevention of autoimmune disease.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(32):11272-7.
2005: Dejean Laurent M; Martinez-Caballero Sonia; Guo Liang; Hughes Cynthia; Teijido Oscar; Ducret Thomas; Ichas François; Korsmeyer Stanley J; Antonsson Bruno; Jonas Elizabeth A; Kinnally Kathleen W
Oligomeric Bax is a component of the putative cytochrome c release channel MAC, mitochondrial apoptosis-induced channel.
Molecular biology of the cell 2005;16(5):2424-32.
2005: Ruiz-Vela Antonio; Opferman Joseph T; Cheng Emily H-Y; Korsmeyer Stanley J
Proapoptotic BAX and BAK control multiple initiator caspases.
EMBO reports 2005;6(4):379-85.
2005: Mandal Malay; Borowski Christine; Palomero Teresa; Ferrando Adolfo A; Oberdoerffer Philipp; Meng Fanyong; Ruiz-Vela Antonio; Ciofani Maria; Zuniga-Pflucker Juan-Carlos; Screpanti Isabella; Look A Thomas; Korsmeyer Stanley J; Rajewsky Klaus; von Boehmer Harald; Aifantis Iannis
The BCL2A1 gene as a pre-T cell receptor-induced regulator of thymocyte survival.
The Journal of experimental medicine 2005;201(4):603-14.
2005: Opferman Joseph T; Iwasaki Hiromi; Ong Christy C; Suh Heikyung; Mizuno Shin-ichi; Akashi Koichi; Korsmeyer Stanley J
Obligate role of anti-apoptotic MCL-1 in the survival of hematopoietic stem cells.
Science (New York, N.Y.) 2005;307(5712):1101-4.
2005: Wang Jing; Iwasaki Hiromi; Krivtsov Andrei; Febbo Phillip G; Thorner Aaron R; Ernst Patricia; Anastasiadou Ema; Kutok Jeffery L; Kogan Scott C; Zinkel Sandra S; Fisher Jill K; Hess Jay L; Golub Todd R; Armstrong Scott A; Akashi Koichi; Korsmeyer Stanley J
Conditional MLL-CBP targets GMP and models therapy-related myeloproliferative disease.
The EMBO journal 2005;24(2):368-81.
2005: Oakes Scott A; Scorrano Luca; Opferman Joseph T; Bassik Michael C; Nishino Mari; Pozzan Tullio; Korsmeyer Stanley J
Proapoptotic BAX and BAK regulate the type 1 inositol trisphosphate receptor and calcium leak from the endoplasmic reticulum.
Proceedings of the National Academy of Sciences of the United States of America 2005;102(1):105-10.
2005: Oh Kyoung Joon; Barbuto Scott; Meyer Natalie; Kim Ryung-Suk; Collier R John; Korsmeyer Stanley J
Conformational changes in BID, a pro-apoptotic BCL-2 family member, upon membrane binding. A site-directed spin labeling study.
The Journal of biological chemistry 2005;280(1):753-67.
2004: Ernst Patricia; Mabon Meghann; Davidson Alan J; Zon Leonard I; Korsmeyer Stanley J
An Mll-dependent Hox program drives hematopoietic progenitor expansion.
Current biology : CB 2004;14(22):2063-9.
2004: Mori M; Burgess D L; Gefrides L A; Foreman P J; Opferman J T; Korsmeyer S J; Cavalheiro E A; Naffah-Mazzacoratti Md G; Noebels J L
Expression of apoptosis inhibitor protein Mcl1 linked to neuroprotection in CNS neurons.
Cell death and differentiation 2004;11(11):1223-33.
2004: Harada Hisashi; Quearry Bonnie; Ruiz-Vela Antonio; Korsmeyer Stanley J
Survival factor-induced extracellular signal-regulated kinase phosphorylates BIM, inhibiting its association with BAX and proapoptotic activity.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(43):15313-7.
2004: Oakes Scott A; Korsmeyer Stanley J
Untangling the web: mitochondrial fission and apoptosis.
Developmental cell 2004;7(4):460-2.
2004: Seo So Young; Chen Ying-Bei; Ivanovska Iva; Ranger Ann M; Hong Suk J; Dawson Valina L; Korsmeyer Stanley J; Bellows David S; Fannjiang Yihru; Hardwick J Marie
BAD is a pro-survival factor prior to activation of its pro-apoptotic function.
The Journal of biological chemistry 2004;279(40):42240-9.
2004: Nam Young-Jae; Mani Kartik; Ashton Anthony W; Peng Chang-Fu; Krishnamurthy Barath; Hayakawa Yukihiro; Lee Peiyee; Korsmeyer Stanley J; Kitsis Richard N
Inhibition of both the extrinsic and intrinsic death pathways through nonhomotypic death-fold interactions.
Molecular cell 2004;15(6):901-12.
2004: Letai Anthony; Sorcinelli Mia D; Beard Caroline; Korsmeyer Stanley J
Antiapoptotic BCL-2 is required for maintenance of a model leukemia.
Cancer cell 2004;6(3):241-9.
2004: Walensky Loren D; Kung Andrew L; Escher Iris; Malia Thomas J; Barbuto Scott; Wright Renee D; Wagner Gerhard; Verdine Gregory L; Korsmeyer Stanley J
Activation of apoptosis in vivo by a hydrocarbon-stapled BH3 helix.
Science (New York, N.Y.) 2004;305(5689):1466-70.
2004: Guo Liang; Pietkiewicz Dawn; Pavlov Evgeny V; Grigoriev Sergey M; Kasianowicz John J; Dejean Laurent M; Korsmeyer Stanley J; Antonsson Bruno; Kinnally Kathleen W
Effects of cytochrome c on the mitochondrial apoptosis-induced channel MAC.
American journal of physiology. Cell physiology 2004;286(5):C1109-17.
2004: Armstrong Scott A; Mabon Meghann E; Silverman Lewis B; Li Aihong; Gribben John G; Fox Edward A; Sallan Stephen E; Korsmeyer Stanley J
FLT3 mutations in childhood acute lymphoblastic leukemia.
Blood 2004;103(9):3544-6.
2004: Ernst Patricia; Fisher Jill K; Avery William; Wade Stacey; Foy Daniel; Korsmeyer Stanley J
Definitive hematopoiesis requires the mixed-lineage leukemia gene.
Developmental cell 2004;6(3):437-43.
2004: Bassik Michael C; Scorrano Luca; Oakes Scott A; Pozzan Tullio; Korsmeyer Stanley J
Phosphorylation of BCL-2 regulates ER Ca2+ homeostasis and apoptosis.
The EMBO journal 2004;23(5):1207-16.
2004: Danial Nika N; Korsmeyer Stanley J
Cell death: critical control points.
Cell 2004;116(2):205-19.
2003: Chavez-Reyes Arturo; Parant John M; Amelse Lisa L; de Oca Luna Roberto Montes; Korsmeyer Stanley J; Lozano Guillermina
Switching mechanisms of cell death in mdm2- and mdm4-null mice by deletion of p53 downstream targets.
Cancer research 2003;63(24):8664-9.
2003: Opferman Joseph T; Letai Anthony; Beard Caroline; Sorcinelli Mia D; Ong Christy C; Korsmeyer Stanley J
Development and maintenance of B and T lymphocytes requires antiapoptotic MCL-1.
Nature 2003;426(6967):671-6.
2003: D'Sa Cleta; Klocke Barbara J; Cecconi Francesco; Lindsten Tulia; Thompson Craig B; Korsmeyer Stanley J; Flavell Richard A; Roth Kevin A
Caspase regulation of genotoxin-induced neural precursor cell death.
Journal of neuroscience research 2003;74(3):435-45.
2003: Hsieh James J-D; Cheng Emily H-Y; Korsmeyer Stanley J
Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression.
Cell 2003;115(3):293-303.
2003: Armstrong Scott A; Golub Todd R; Korsmeyer Stanley J
MLL-rearranged leukemias: insights from gene expression profiling.
Seminars in hematology 2003;40(4):268-73.
2003: Oakes Scott A; Opferman Joseph T; Pozzan Tullio; Korsmeyer Stanley J; Scorrano Luca
Regulation of endoplasmic reticulum Ca2+ dynamics by proapoptotic BCL-2 family members.
Biochemical pharmacology 2003;66(8):1335-40.
2003: Dong Hongxin; Fazzaro Alicia; Xiang Chuanxi; Korsmeyer Stanley J; Jacquin Mark F; McDonald John W
Enhanced oligodendrocyte survival after spinal cord injury in Bax-deficient mice and mice with delayed Wallerian degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(25):8682-91.
2003: Davidson Alan J; Ernst Patricia; Wang Yuan; Dekens Marcus P S; Kingsley Paul D; Palis James; Korsmeyer Stanley J; Daley George Q; Zon Leonard I
cdx4 mutants fail to specify blood progenitors and can be rescued by multiple hox genes.
Nature 2003;425(6955):300-6.
2003: Armstrong Scott A; Korsmeyer Stanley J
Comparison of human genomics and genetic models of cancer to identify novel therapeutic targets.
Cell cycle (Georgetown, Tex.) 2003;2(5):408-9.
2003: Danial Nika N; Gramm Colette F; Scorrano Luca; Zhang Chen-Yu; Krauss Stefan; Ranger Ann M; Datta Sandeep Robert; Greenberg Michael E; Licklider Lawrence J; Lowell Bradford B; Gygi Steven P; Korsmeyer Stanley J
BAD and glucokinase reside in a mitochondrial complex that integrates glycolysis and apoptosis.
Nature 2003;424(6951):952-6.
2003: Ranger Ann M; Zha Jiping; Harada Hisashi; Datta Sandeep Robert; Danial Nika N; Gilmore Andrew P; Kutok Jeffery L; Le Beau Michelle M; Greenberg Michael E; Korsmeyer Stanley J
Bad-deficient mice develop diffuse large B cell lymphoma.
Proceedings of the National Academy of Sciences of the United States of America 2003;100(16):9324-9.
2003: Cheng Emily H Y; Sheiko Tatiana V; Fisher Jill K; Craigen William J; Korsmeyer Stanley J
VDAC2 inhibits BAK activation and mitochondrial apoptosis.
Science (New York, N.Y.) 2003;301(5632):513-7.
2003: Ferrando Adolfo A; Armstrong Scott A; Neuberg Donna S; Sallan Stephen E; Silverman Lewis B; Korsmeyer Stanley J; Look A Thomas
Gene expression signatures in MLL-rearranged T-lineage and B-precursor acute leukemias: dominance of HOX dysregulation.
Blood 2003;102(1):262-8.
2003: Scorrano Luca; Korsmeyer Stanley J
Mechanisms of cytochrome c release by proapoptotic BCL-2 family members.
Biochemical and biophysical research communications 2003;304(3):437-44.
2003: Opferman Joseph T; Korsmeyer Stanley J
Apoptosis in the development and maintenance of the immune system.
Nature immunology 2003;4(5):410-5.
2003: Kandasamy Karthikeyan; Srinivasula Srinivasa M; Alnemri Emad S; Thompson Craig B; Korsmeyer Stanley J; Bryant Joseph L; Srivastava Rakesh K
Involvement of proapoptotic molecules Bax and Bak in tumor necrosis factor-related apoptosis-inducing ligand (TRAIL)-induced mitochondrial disruption and apoptosis: differential regulation of cytochrome c and Smac/DIABLO release.
Cancer research 2003;63(7):1712-21.
2003: Scorrano Luca; Oakes Scott A; Opferman Joseph T; Cheng Emily H; Sorcinelli Mia D; Pozzan Tullio; Korsmeyer Stanley J
BAX and BAK regulation of endoplasmic reticulum Ca2+: a control point for apoptosis.
Science (New York, N.Y.) 2003;300(5616):135-9.
2003: Johnson Hillary; Scorrano Luca; Korsmeyer Stanley J; Ley Timothy J
Cell death induced by granzyme C.
Blood 2003;101(8):3093-101.
2003: Perfettini Jean-Luc; Ojcius David M; Andrews Charles W; Korsmeyer Stanley J; Rank Roger G; Darville Toni
Role of proapoptotic BAX in propagation of Chlamydia muridarum (the mouse pneumonitis strain of Chlamydia trachomatis) and the host inflammatory response.
The Journal of biological chemistry 2003;278(11):9496-502.
2003: Armstrong Scott A; Kung Andrew L; Mabon Meghann E; Silverman Lewis B; Stam Ronald W; Den Boer Monique L; Pieters Rob; Kersey John H; Sallan Stephen E; Fletcher Jonathan A; Golub Todd R; Griffin James D; Korsmeyer Stanley J
Inhibition of FLT3 in MLL. Validation of a therapeutic target identified by gene expression based classification.
Cancer cell 2003;3(2):173-83.
2003: Stam Ronald W; den Boer Monique L; Meijerink Jules P P; Ebus Marli E G; Peters Godefridus J; Noordhuis Paul; Janka-Schaub Gritta E; Armstrong Scott A; Korsmeyer Stanley J; Pieters Rob
Differential mRNA expression of Ara-C-metabolizing enzymes explains Ara-C sensitivity in MLL gene-rearranged infant acute lymphoblastic leukemia.
Blood 2003;101(4):1270-6.
2003: Zinkel Sandra S; Ong Christy C; Ferguson David O; Iwasaki Hiromi; Akashi Koichi; Bronson Roderick T; Kutok Jeffery L; Alt Frederick W; Korsmeyer Stanley J
Proapoptotic BID is required for myeloid homeostasis and tumor suppression.
Genes & development 2003;17(2):229-39.
2003: Takai Yasushi; Canning Jacqueline; Perez Gloria I; Pru James K; Schlezinger Jennifer J; Sherr David H; Kolesnick Richard N; Yuan Junying; Flavell Richard A; Korsmeyer Stanley J; Tilly Jonathan L
Bax, caspase-2, and caspase-3 are required for ovarian follicle loss caused by 4-vinylcyclohexene diepoxide exposure of female mice in vivo.
Endocrinology 2003;144(1):69-74.
2003: Hsieh James J-D; Ernst Patricia; Erdjument-Bromage Hediye; Tempst Paul; Korsmeyer Stanley J
Proteolytic cleavage of MLL generates a complex of N- and C-terminal fragments that confers protein stability and subnuclear localization.
Molecular and cellular biology 2003;23(1):186-94.
2002: Datta Sandeep Robert; Ranger Ann M; Lin Michael Z; Sturgill James Fitzhugh; Ma Yong-Chao; Cowan Chris W; Dikkes Pieter; Korsmeyer Stanley J; Greenberg Michael E
Survival factor-mediated BAD phosphorylation raises the mitochondrial threshold for apoptosis.
Developmental cell 2002;3(5):631-43.
2002: Sax Joanna K; Fei Peiwen; Murphy Maureen E; Bernhard Eric; Korsmeyer Stanley J; El-Deiry Wafik S
BID regulation by p53 contributes to chemosensitivity.
Nature cell biology 2002;4(11):842-9.
2002: Letai Anthony; Bassik Michael C; Walensky Loren D; Sorcinelli Mia D; Weiler Solly; Korsmeyer Stanley J
Distinct BH3 domains either sensitize or activate mitochondrial apoptosis, serving as prototype cancer therapeutics.
Cancer cell 2002;2(3):183-92.
2002: Juin Philippe; Hunt Abigail; Littlewood Trevor; Griffiths Beatrice; Swigart Lamorna Brown; Korsmeyer Stanley; Evan Gerard
c-Myc functionally cooperates with Bax to induce apoptosis.
Molecular and cellular biology 2002;22(17):6158-69.
2002: Gilmore Andrew P; Valentijn Anthony J; Wang Pengbo; Ranger Ann M; Bundred Nigel; O'Hare Michael J; Wakeling Alan; Korsmeyer Stanley J; Streuli Charles H
Activation of BAD by therapeutic inhibition of epidermal growth factor receptor and transactivation by insulin-like growth factor receptor.
The Journal of biological chemistry 2002;277(31):27643-50.
2002: Fantin Valeria R; Berardi Marcelo J; Scorrano Luca; Korsmeyer Stanley J; Leder Philip
A novel mitochondriotoxic small molecule that selectively inhibits tumor cell growth.
Cancer cell 2002;2(1):29-42.
2002: Armstrong Scott A; Hsieh James J-D; Korsmeyer Stanley J
Genomic approaches to the pathogenesis and treatment of acute lymphoblastic leukemias.
Current opinion in hematology 2002;9(4):339-44.
2002: Ernst Patricia; Wang Jing; Korsmeyer Stanley J
The role of MLL in hematopoiesis and leukemia.
Current opinion in hematology 2002;9(4):282-7.
2002: McGill Gaël G; Horstmann Martin; Widlund Hans R; Du Jinyan; Motyckova Gabriela; Nishimura Emi K; Lin Yi-Ling; Ramaswamy Sridhar; Avery William; Ding Han-Fei; Jordan Siobhán A; Jackson Ian J; Korsmeyer Stanley J; Golub Todd R; Fisher David E
Bcl2 regulation by the melanocyte master regulator Mitf modulates lineage survival and melanoma cell viability.
Cell 2002;109(6):707-18.
2002: Eischen Christine M; Rehg Jerold E; Korsmeyer Stanley J; Cleveland John L
Loss of Bax alters tumor spectrum and tumor numbers in ARF-deficient mice.
Cancer research 2002;62(7):2184-91.
2002: Russell Lonnie D; Chiarini-Garcia Helio; Korsmeyer Stanley J; Knudson C Michael
Bax-dependent spermatogonia apoptosis is required for testicular development and spermatogenesis.
Biology of reproduction 2002;66(4):950-8.
2002: Matikainen Tiina M; Moriyama Toshitake; Morita Yutaka; Perez Gloria I; Korsmeyer Stanley J; Sherr David H; Tilly Jonathan L
Ligand activation of the aromatic hydrocarbon receptor transcription factor drives Bax-dependent apoptosis in developing fetal ovarian germ cells.
Endocrinology 2002;143(2):615-20.
2002: Plesnila Nikolaus; Zinkel Sandra; Amin-Hanjani Sepideh; Qiu Jianhua; Korsmeyer Stanley J; Moskowitz Michael A
Function of BID -- a molecule of the bcl-2 family -- in ischemic cell death in the brain.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 2002;34(1-2):37-41.
2002: Scorrano Luca; Ashiya Mona; Buttle Karolyn; Weiler Solly; Oakes Scott A; Mannella Carmen A; Korsmeyer Stanley J
A distinct pathway remodels mitochondrial cristae and mobilizes cytochrome c during apoptosis.
Developmental cell 2002;2(1):55-67.
2002: Armstrong Scott A; Staunton Jane E; Silverman Lewis B; Pieters Rob; den Boer Monique L; Minden Mark D; Sallan Stephen E; Lander Eric S; Golub Todd R; Korsmeyer Stanley J
MLL translocations specify a distinct gene expression profile that distinguishes a unique leukemia.
Nature genetics 2002;30(1):41-7.
2001: Plesnila N; Zinkel S; Le D A; Amin-Hanjani S; Wu Y; Qiu J; Chiarugi A; Thomas S S; Kohane D S; Korsmeyer S J; Moskowitz M A
BID mediates neuronal cell death after oxygen/ glucose deprivation and focal cerebral ischemia.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(26):15318-23.
2001: Ross A J; Amy S P; Mahar P L; Lindsten T; Knudson C M; Thompson C B; Korsmeyer S J; MacGregor G R
BCLW mediates survival of postmitotic Sertoli cells by regulating BAX activity.
Developmental biology 2001;239(2):295-308.
2001: Pavlov E V; Priault M; Pietkiewicz D; Cheng E H; Antonsson B; Manon S; Korsmeyer S J; Mannella C A; Kinnally K W
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast.
The Journal of cell biology 2001;155(5):725-31.
2001: Eischen C M; Roussel M F; Korsmeyer S J; Cleveland J L
Bax loss impairs Myc-induced apoptosis and circumvents the selection of p53 mutations during Myc-mediated lymphomagenesis.
Molecular and cellular biology 2001;21(22):7653-62.
2001: Zaidi A U; McDonough J S; Klocke B J; Latham C B; Korsmeyer S J; Flavell R A; Schmidt R E; Roth K A
Chloroquine-induced neuronal cell death is p53 and Bcl-2 family-dependent but caspase-independent.
Journal of neuropathology and experimental neurology 2001;60(10):937-45.
2001: Cheng E H; Wei M C; Weiler S; Flavell R A; Mak T W; Lindsten T; Korsmeyer S J
BCL-2, BCL-X(L) sequester BH3 domain-only molecules preventing BAX- and BAK-mediated mitochondrial apoptosis.
Molecular cell 2001;8(3):705-11.
2001: Harada H; Andersen J S; Mann M; Terada N; Korsmeyer S J
p70S6 kinase signals cell survival as well as growth, inactivating the pro-apoptotic molecule BAD.
Proceedings of the National Academy of Sciences of the United States of America 2001;98(17):9666-70.
2001: Matikainen T; Perez G I; Jurisicova A; Pru J K; Schlezinger J J; Ryu H Y; Laine J; Sakai T; Korsmeyer S J; Casper R F; Sherr D H; Tilly J L
Aromatic hydrocarbon receptor-driven Bax gene expression is required for premature ovarian failure caused by biohazardous environmental chemicals.
Nature genetics 2001;28(4):355-60.
2001: Morita Y; Maravei D V; Bergeron L; Wang S; Perez G I; Tsutsumi O; Taketani Y; Asano M; Horai R; Korsmeyer S J; Iwakura Y; Yuan J; Tilly J L
Caspase-2 deficiency prevents programmed germ cell death resulting from cytokine insufficiency but not meiotic defects caused by loss of ataxia telangiectasia-mutated (Atm) gene function.
Cell death and differentiation 2001;8(6):614-20.
2001: Leonard J R; D'Sa C; Cahn B R; Korsmeyer S J; Roth K A
Bid regulation of neuronal apoptosis.
Brain research. Developmental brain research 2001;128(2):187-90.
2001: Ranger A M; Malynn B A; Korsmeyer S J
Mouse models of cell death.
Nature genetics 2001;28(2):113-8.
2001: Wei M C; Zong W X; Cheng E H; Lindsten T; Panoutsakopoulou V; Ross A J; Roth K A; MacGregor G R; Thompson C B; Korsmeyer S J
Proapoptotic BAX and BAK: a requisite gateway to mitochondrial dysfunction and death.
Science (New York, N.Y.) 2001;292(5517):727-30.
2001: Ernst P; Wang J; Huang M; Goodman R H; Korsmeyer S J
MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein.
Molecular and cellular biology 2001;21(7):2249-58.
2001: Mootha V K; Wei M C; Buttle K F; Scorrano L; Panoutsakopoulou V; Mannella C A; Korsmeyer S J
A reversible component of mitochondrial respiratory dysfunction in apoptosis can be rescued by exogenous cytochrome c.
The EMBO journal 2001;20(4):661-71.
2001: Wen R; Wang D; McKay C; Bunting K D; Marine J C; Vanin E F; Zambetti G P; Korsmeyer S J; Ihle J N; Cleveland J L
Jak3 selectively regulates Bax and Bcl-2 expression to promote T-cell development.
Molecular and cellular biology 2001;21(2):678-89.
2000: Korsmeyer S J; Wei M C; Saito M; Weiler S; Oh K J; Schlesinger P H
Pro-apoptotic cascade activates BID, which oligomerizes BAK or BAX into pores that result in the release of cytochrome c.
Cell death and differentiation 2000;7(12):1166-73.
2000: Lindsten T; Ross A J; King A; Zong W X; Rathmell J C; Shiels H A; Ulrich E; Waymire K G; Mahar P; Frauwirth K; Chen Y; Wei M; Eng V M; Adelman D M; Simon M C; Ma A; Golden J A; Evan G; Korsmeyer S J; MacGregor G R; Thompson C B
The combined functions of proapoptotic Bcl-2 family members bak and bax are essential for normal development of multiple tissues.
Molecular cell 2000;6(6):1389-99.
2000: Zha J; Weiler S; Oh K J; Wei M C; Korsmeyer S J
Posttranslational N-myristoylation of BID as a molecular switch for targeting mitochondria and apoptosis.
Science (New York, N.Y.) 2000;290(5497):1761-5.
2000: Wei M C; Lindsten T; Mootha V K; Weiler S; Gross A; Ashiya M; Thompson C B; Korsmeyer S J
tBID, a membrane-targeted death ligand, oligomerizes BAK to release cytochrome c.
Genes & development 2000;14(16):2060-71.
2000: Gross A; Pilcher K; Blachly-Dyson E; Basso E; Jockel J; Bassik M C; Korsmeyer S J; Forte M
Biochemical and genetic analysis of the mitochondrial response of yeast to BAX and BCL-X(L).
Molecular and cellular biology 2000;20(9):3125-36.
2000: Shirasawa S; Arata A; Onimaru H; Roth K A; Brown G A; Horning S; Arata S; Okumura K; Sasazuki T; Korsmeyer S J
Rnx deficiency results in congenital central hypoventilation.
Nature genetics 2000;24(3):287-90.
1999: Pritchard D M; Potten C S; Korsmeyer S J; Roberts S; Hickman J A
Damage-induced apoptosis in intestinal epithelia from bcl-2-null and bax-null mice: investigations of the mechanistic determinants of epithelial apoptosis in vivo.
Oncogene 1999;18(51):7287-93.
1999: Hanson R D; Hess J L; Yu B D; Ernst P; van Lohuizen M; Berns A; van der Lugt N M; Shashikant C S; Ruddle F H; Seto M; Korsmeyer S J
Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(25):14372-7.
1999: Yamamoto K; Ichijo H; Korsmeyer S J
BCL-2 is phosphorylated and inactivated by an ASK1/Jun N-terminal protein kinase pathway normally activated at G(2)/M.
Molecular and cellular biology 1999;19(12):8469-78.
1999: Yin X M; Wang K; Gross A; Zhao Y; Zinkel S; Klocke B; Roth K A; Korsmeyer S J
Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis.
Nature 1999;400(6747):886-91.
1999: Lewis J; Oyler G A; Ueno K; Fannjiang Y R; Chau B N; Vornov J; Korsmeyer S J; Zou S; Hardwick J M
Inhibition of virus-induced neuronal apoptosis by Bax.
Nature medicine 1999;5(7):832-5.
1999: Schorr K; Li M; Bar-Peled U; Lewis A; Heredia A; Lewis B; Knudson C M; Korsmeyer S J; Jäger R; Weiher H; Furth P A
Gain of Bcl-2 is more potent than bax loss in regulating mammary epithelial cell survival in vivo.
Cancer research 1999;59(11):2541-5.
1999: Harada H; Becknell B; Wilm M; Mann M; Huang L J; Taylor S S; Scott J D; Korsmeyer S J
Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A.
Molecular cell 1999;3(4):413-22.
1999: Korsmeyer S J
BCL-2 gene family and the regulation of programmed cell death.
Cancer research 1999;59(7 Suppl):1693s-1700s.
1999: Bar-Peled O; Knudson M; Korsmeyer S J; Rothstein J D
Motor neuron degeneration is attenuated in bax-deficient neurons in vitro.
Journal of neuroscience research 1999;55(5):542-56.
1999: Perez G I; Robles R; Knudson C M; Flaws J A; Korsmeyer S J; Tilly J L
Prolongation of ovarian lifespan into advanced chronological age by Bax-deficiency.
Nature genetics 1999;21(2):200-3.
1999: Gross A; Yin X M; Wang K; Wei M C; Jockel J; Milliman C; Erdjument-Bromage H; Tempst P; Korsmeyer S J
Caspase cleaved BID targets mitochondria and is required for cytochrome c release, while BCL-XL prevents this release but not tumor necrosis factor-R1/Fas death.
The Journal of biological chemistry 1999;274(2):1156-63.
1999: Korsmeyer S J
Programmed cell death and the regulation of homeostasis.
Harvey lectures 1999;95():21-41.
1999: Korsmeyer S J; Gross A; Harada H; Zha J; Wang K; Yin X M; Wei M; Zinkel S
Death and survival signals determine active/inactive conformations of pro-apoptotic BAX, BAD, and BID molecules.
Cold Spring Harbor symposia on quantitative biology 1999;64():343-50.
1998: Yu B D; Hanson R D; Hess J L; Horning S E; Korsmeyer S J
MLL, a mammalian trithorax-group gene, functions as a transcriptional maintenance factor in morphogenesis.
Proceedings of the National Academy of Sciences of the United States of America 1998;95(18):10632-6.
1998: Gross A; Jockel J; Wei M C; Korsmeyer S J
Enforced dimerization of BAX results in its translocation, mitochondrial dysfunction and apoptosis.
The EMBO journal 1998;17(14):3878-85.
1998: Chao D T; Korsmeyer S J
BCL-2 family: regulators of cell death.
Annual review of immunology 1998;16():395-419.
1997: Perez G I; Knudson C M; Leykin L; Korsmeyer S J; Tilly J L
Apoptosis-associated signaling pathways are required for chemotherapy-mediated female germ cell destruction.
Nature medicine 1997;3(11):1228-32.
1997: Schlesinger P H; Gross A; Yin X M; Yamamoto K; Saito M; Waksman G; Korsmeyer S J
Comparison of the ion channel characteristics of proapoptotic BAX and antiapoptotic BCL-2.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(21):11357-62.
1997: Chao D T; Korsmeyer S J
BCL-XL-regulated apoptosis in T cell development.
International immunology 1997;9(9):1375-84.
1997: Zha J; Harada H; Osipov K; Jockel J; Waksman G; Korsmeyer S J
BH3 domain of BAD is required for heterodimerization with BCL-XL and pro-apoptotic activity.
The Journal of biological chemistry 1997;272(39):24101-4.
1997: Hess J L; Yu B D; Li B; Hanson R; Korsmeyer S J
Defects in yolk sac hematopoiesis in Mll-null embryos.
Blood 1997;90(5):1799-806.
1997: Kawabe T; Muslin A J; Korsmeyer S J
HOX11 interacts with protein phosphatases PP2A and PP1 and disrupts a G2/M cell-cycle checkpoint.
Nature 1997;385(6615):454-8.
1997: Merry D E; Korsmeyer S J
Bcl-2 gene family in the nervous system.
Annual review of neuroscience 1997;20():245-67.
1996: Xiang J; Chao D T; Korsmeyer S J
BAX-induced cell death may not require interleukin 1 beta-converting enzyme-like proteases.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(25):14559-63.
1996: Zha J; Harada H; Yang E; Jockel J; Korsmeyer S J
Serine phosphorylation of death agonist BAD in response to survival factor results in binding to 14-3-3 not BCL-X(L)
Cell 1996;87(4):619-28.
1996: Wang K; Yin X M; Chao D T; Milliman C L; Korsmeyer S J
BID: a novel BH3 domain-only death agonist.
Genes & development 1996;10(22):2859-69.
1996: Linette G P; Li Y; Roth K; Korsmeyer S J
Cross talk between cell death and cell cycle progression: BCL-2 regulates NFAT-mediated activation.
Proceedings of the National Academy of Sciences of the United States of America 1996;93(18):9545-52.
1996: Yang E; Korsmeyer S J
Molecular thanatopsis: a discourse on the BCL2 family and cell death.
Blood 1996;88(2):386-401.
1995: Yu B D; Hess J L; Horning S E; Brown G A; Korsmeyer S J
Altered Hox expression and segmental identity in Mll-mutant mice.
Nature 1995;378(6556):505-8.
1995: Knudson C M; Tung K S; Tourtellotte W G; Brown G A; Korsmeyer S J
Bax-deficient mice with lymphoid hyperplasia and male germ cell death.
Science (New York, N.Y.) 1995;270(5233):96-9.
1995: Chao D T; Linette G P; Boise L H; White L S; Thompson C B; Korsmeyer S J
Bcl-XL and Bcl-2 repress a common pathway of cell death.
The Journal of experimental medicine 1995;182(3):821-8.
1995: Sedlak T W; Oltvai Z N; Yang E; Wang K; Boise L H; Thompson C B; Korsmeyer S J
Multiple Bcl-2 family members demonstrate selective dimerizations with Bax.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(17):7834-8.
1995: Linette G P; Hess J L; Sentman C L; Korsmeyer S J
Peripheral T-cell lymphoma in lckpr-bcl-2 transgenic mice.
Blood 1995;86(4):1255-60.
1995: Korsmeyer S J; Yin X M; Oltvai Z N; Veis-Novack D J; Linette G P
Reactive oxygen species and the regulation of cell death by the Bcl-2 gene family.
Biochimica et biophysica acta 1995;1271(1):63-6.
1995: Sorenson C M; Rogers S A; Korsmeyer S J; Hammerman M R
Fulminant metanephric apoptosis and abnormal kidney development in bcl-2-deficient mice.
The American journal of physiology 1995;268(1 Pt 2):F73-81.
1995: Yang E; Zha J; Jockel J; Boise L H; Thompson C B; Korsmeyer S J
Bad, a heterodimeric partner for Bcl-XL and Bcl-2, displaces Bax and promotes cell death.
Cell 1995;80(2):285-91.
1995: Yin X M; Oltvai Z N; Korsmeyer S J
Heterodimerization with Bax is required for Bcl-2 to repress cell death.
Current topics in microbiology and immunology 1995;194():331-8.
1994: Kim H R; Upadhyay S; Korsmeyer S; Deuel T F
Platelet-derived growth factor (PDGF) B and A homodimers transform murine fibroblasts depending on the genetic background of the cell.
The Journal of biological chemistry 1994;269(48):30604-8.
1994: Linette G P; Grusby M J; Hedrick S M; Hansen T H; Glimcher L H; Korsmeyer S J
Bcl-2 is upregulated at the CD4+ CD8+ stage during positive selection and promotes thymocyte differentiation at several control points.
Immunity 1994;1(3):197-205.
1994: Yin X M; Oltvai Z N; Korsmeyer S J
BH1 and BH2 domains of Bcl-2 are required for inhibition of apoptosis and heterodimerization with Bax.
Nature 1994;369(6478):321-3.
1994: Merry D E; Veis D J; Hickey W F; Korsmeyer S J
bcl-2 protein expression is widespread in the developing nervous system and retained in the adult PNS.
Development (Cambridge, England) 1994;120(2):301-11.
1994: Yin X M; Oltvai Z N; Veis-Novack D J; Linette G P; Korsmeyer S J
Bcl-2 gene family and the regulation of programmed cell death.
Cold Spring Harbor symposia on quantitative biology 1994;59():387-93.
1993: Korsmeyer S J; Shutter J R; Veis D J; Merry D E; Oltvai Z N
Bcl-2/Bax: a rheostat that regulates an anti-oxidant pathway and cell death.
Seminars in cancer biology 1993;4(6):327-32.
1993: Veis D J; Sorenson C M; Shutter J R; Korsmeyer S J
Bcl-2-deficient mice demonstrate fulminant lymphoid apoptosis, polycystic kidneys, and hypopigmented hair.
Cell 1993;75(2):229-40.
1993: Hockenbery D M; Oltvai Z N; Yin X M; Milliman C L; Korsmeyer S J
Bcl-2 functions in an antioxidant pathway to prevent apoptosis.
Cell 1993;75(2):241-51.
1993: Veis D J; Sentman C L; Bach E A; Korsmeyer S J
Expression of the Bcl-2 protein in murine and human thymocytes and in peripheral T lymphocytes.
Journal of immunology (Baltimore, Md. : 1950) 1993;151(5):2546-54.
1993: Oltvai Z N; Milliman C L; Korsmeyer S J
Bcl-2 heterodimerizes in vivo with a conserved homolog, Bax, that accelerates programmed cell death.
Cell 1993;74(4):609-19.
1993: Domer P H; Fakharzadeh S S; Chen C S; Jockel J; Johansen L; Silverman G A; Kersey J H; Korsmeyer S J
Acute mixed-lineage leukemia t(4;11)(q21;q23) generates an MLL-AF4 fusion product.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(16):7884-8.
1993: Young R L; Korsmeyer S J
A negative regulatory element in the bcl-2 5'-untranslated region inhibits expression from an upstream promoter.
Molecular and cellular biology 1993;13(6):3686-97.
1992: McGuire E A; Rintoul C E; Sclar G M; Korsmeyer S J
Thymic overexpression of Ttg-1 in transgenic mice results in T-cell acute lymphoblastic leukemia/lymphoma.
Molecular and cellular biology 1992;12(9):4186-96.
1992: Korsmeyer S J
Bcl-2 initiates a new category of oncogenes: regulators of cell death.
Blood 1992;80(4):879-86.
1992: Korsmeyer S J
Chromosomal translocations in lymphoid malignancies reveal novel proto-oncogenes.
Annual review of immunology 1992;10():785-807.
1992: Korsmeyer S J
Bcl-2: an antidote to programmed cell death.
Cancer surveys 1992;15():105-18.
1991: Sentman C L; Shutter J R; Hockenbery D; Kanagawa O; Korsmeyer S J
bcl-2 inhibits multiple forms of apoptosis but not negative selection in thymocytes.
Cell 1991;67(5):879-88.
1991: Nuñez G; Hockenbery D; McDonnell T J; Sorensen C M; Korsmeyer S J
Bcl-2 maintains B cell memory.
Nature 1991;353(6339):71-3.
1991: Hockenbery D M; Zutter M; Hickey W; Nahm M; Korsmeyer S J
BCL2 protein is topographically restricted in tissues characterized by apoptotic cell death.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(16):6961-5.
1991: Zutter M; Hockenbery D; Silverman G A; Korsmeyer S J
Immunolocalization of the Bcl-2 protein within hematopoietic neoplasms.
Blood 1991;78(4):1062-8.
1991: Hatano M; Roberts C W; Minden M; Crist W M; Korsmeyer S J
Deregulation of a homeobox gene, HOX11, by the t(10;14) in T cell leukemia.
Science (New York, N.Y.) 1991;253(5015):79-82.
1991: Silverman G A; Jockel J I; Domer P H; Mohr R M; Taillon-Miller P; Korsmeyer S J
Yeast artificial chromosome cloning of a two-megabase-size contig within chromosomal band 18q21 establishes physical linkage between BCL2 and plasminogen activator inhibitor type-2.
Genomics 1991;9(2):219-28.
1991: McGuire E A; Davis A R; Korsmeyer S J
T-cell translocation gene 1 (Ttg-1) encodes a nuclear protein normally expressed in neural lineage cells.
Blood 1991;77(3):599-606.
1991: McDonnell T J; Korsmeyer S J
Progression from lymphoid hyperplasia to high-grade malignant lymphoma in mice transgenic for the t(14; 18).
Nature 1991;349(6306):254-6.
1990: Silverman G A; Green E D; Young R L; Jockel J I; Domer P H; Korsmeyer S J
Meiotic recombination between yeast artificial chromosomes yields a single clone containing the entire BCL2 protooncogene.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(24):9913-7.
1990: Hockenbery D; Nuñez G; Milliman C; Schreiber R D; Korsmeyer S J
Bcl-2 is an inner mitochondrial membrane protein that blocks programmed cell death.
Nature 1990;348(6299):334-6.
1990: Nuñez G; London L; Hockenbery D; Alexander M; McKearn J P; Korsmeyer S J
Deregulated Bcl-2 gene expression selectively prolongs survival of growth factor-deprived hemopoietic cell lines.
Journal of immunology (Baltimore, Md. : 1950) 1990;144(9):3602-10.
1990: McDonnell T J; Nunez G; Platt F M; Hockenberry D; London L; McKearn J P; Korsmeyer S J
Deregulated Bcl-2-immunoglobulin transgene expands a resting but responsive immunoglobulin M and D-expressing B-cell population.
Molecular and cellular biology 1990;10(5):1901-7.
1990: Zutter M; Hockett R D; Roberts C W; McGuire E A; Bloomstone J; Morton C C; Deaven L L; Crist W M; Carroll A J; Korsmeyer S J
The t(10;14)(q24;q11) of T-cell acute lymphoblastic leukemia juxtaposes the delta T-cell receptor with TCL3, a conserved and activated locus at 10q24.
Proceedings of the National Academy of Sciences of the United States of America 1990;87(8):3161-5.
1990: Korsmeyer S J; McDonnell T J; Nunez G; Hockenbery D; Young R
Bcl-2: B cell life, death and neoplasia.
Current topics in microbiology and immunology 1990;166():203-7.
1989: Hockett R D; Nuñez G; Korsmeyer S J
Evolutionary comparison of murine and human delta T-cell receptor deleting elements.
The New biologist 1989;1(3):266-74.
1989: Silverman G A; Ye R D; Pollock K M; Sadler J E; Korsmeyer S J
Use of yeast artificial chromosome clones for mapping and walking within human chromosome segment 18q21.3.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(19):7485-9.
1989: Nunez G; Seto M; Seremetis S; Ferrero D; Grignani F; Korsmeyer S J; Dalla-Favera R
Growth- and tumor-promoting effects of deregulated BCL2 in human B-lymphoblastoid cells.
Proceedings of the National Academy of Sciences of the United States of America 1989;86(12):4589-93.
1989: McGuire E A; Hockett R D; Pollock K M; Bartholdi M F; O'Brien S J; Korsmeyer S J
The t(11;14)(p15;q11) in a T-cell acute lymphoblastic leukemia cell line activates multiple transcripts, including Ttg-1, a gene encoding a potential zinc finger protein.
Molecular and cellular biology 1989;9(5):2124-32.
1989: McDonnell T J; Deane N; Platt F M; Nunez G; Jaeger U; McKearn J P; Korsmeyer S J
bcl-2-immunoglobulin transgenic mice demonstrate extended B cell survival and follicular lymphoproliferation.
Cell 1989;57(1):79-88.
1988: Hockett R D; de Villartay J P; Pollock K; Poplack D G; Cohen D I; Korsmeyer S J
Human T-cell antigen receptor (TCR) delta-chain locus and elements responsible for its deletion are within the TCR alpha-chain locus.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(24):9694-8.
1988: Guglielmi P; Bakhshi A; Cogne M; Seligmann M; Korsmeyer S J
Multiple genomic defects result in an alternative RNA splice creating a human gamma H chain disease protein.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(5):1762-8.
1988: Cogné M; Bakhshi A; Korsmeyer S J; Guglielmi P
Gene mutations and alternate RNA splicing result in truncated Ig L chains in human gamma H chain disease.
Journal of immunology (Baltimore, Md. : 1950) 1988;141(5):1738-44.
1988: de Villartay J P; Hockett R D; Coran D; Korsmeyer S J; Cohen D I
Deletion of the human T-cell receptor delta-gene by a site-specific recombination.
Nature 1988;335(6186):170-4.
1988: Crescenzi M; Seto M; Herzig G P; Weiss P D; Griffith R C; Korsmeyer S J
Thermostable DNA polymerase chain amplification of t(14;18) chromosome breakpoints and detection of minimal residual disease.
Proceedings of the National Academy of Sciences of the United States of America 1988;85(13):4869-73.
1988: Graninger W B; Goldman P L; Morton C C; O'Brien S J; Korsmeyer S J
The kappa-deleting element. Germline and rearranged, duplicated and dispersed forms.
The Journal of experimental medicine 1988;167(2):488-501.
1988: Seto M; Jaeger U; Hockett R D; Graninger W; Bennett S; Goldman P; Korsmeyer S J
Alternative promoters and exons, somatic mutation and deregulation of the Bcl-2-Ig fusion gene in lymphoma.
The EMBO journal 1988;7(1):123-31.
1988: Korsmeyer S J
B-lymphoid neoplasms: immunoglobulin genes as molecular determinants of clonality, lineage, differentiation, and translocation.
Advances in internal medicine 1988;33():1-15.
1988: Korsmeyer S J; Hockett R D; McGuire E A; Nunez G
Human delta T cell receptor: rearrangement, deletion, and translocation.
Princess Takamatsu symposia 1988;19():137-45.
1987: de Villartay J P; Lewis D; Hockett R; Waldmann T A; Korsmeyer S J; Cohen D I
Deletional rearrangement in the human T-cell receptor alpha-chain locus.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(23):8608-12.
1987: Lipford E; Wright J J; Urba W; Whang-Peng J; Kirsch I R; Raffeld M; Cossman J; Longo D L; Bakhshi A; Korsmeyer S J
Refinement of lymphoma cytogenetics by the chromosome 18q21 major breakpoint region.
Blood 1987;70(6):1816-23.
1987: Graninger W B; Seto M; Boutain B; Goldman P; Korsmeyer S J
Expression of Bcl-2 and Bcl-2-Ig fusion transcripts in normal and neoplastic cells.
The Journal of clinical investigation 1987;80(5):1512-5.
1987: Wright J J; Poplack D G; Bakhshi A; Reaman G; Cole D; Jensen J P; Korsmeyer S J
Gene rearrangements as markers of clonal variation and minimal residual disease in acute lymphoblastic leukemia.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1987;5(5):735-41.
1987: Raffeld M; Wright J J; Lipford E; Cossman J; Longo D L; Bakhshi A; Korsmeyer S J
Clonal evolution of t(14;18) follicular lymphomas demonstrated by immunoglobulin genes and the 18q21 major breakpoint region.
Cancer research 1987;47(10):2537-42.
1987: Bakhshi A; Wright J J; Graninger W; Seto M; Owens J; Cossman J; Jensen J P; Goldman P; Korsmeyer S J
Mechanism of the t(14;18) chromosomal translocation: structural analysis of both derivative 14 and 18 reciprocal partners.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(8):2396-400.
1986: Bakhshi A; Guglielmi P; Coligan J E; Gamza F; Waldmann T A; Korsmeyer S J
A pre-translational defect in a case of human mu heavy chain disease.
Molecular immunology 1986;23(7):725-32.
1986: Bakhshi A; Guglielmi P; Siebenlist U; Ravetch J V; Jensen J P; Korsmeyer S J
A DNA insertion/deletion necessitates an aberrant RNA splice accounting for a mu heavy chain disease protein.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(8):2689-93.
1985: Siminovitch K A; Bakhshi A; Goldman P; Korsmeyer S J
A uniform deleting element mediates the loss of kappa genes in human B cells.
Nature 1985;316(6025):260-2.
1985: Bakhshi A; Jensen J P; Goldman P; Wright J J; McBride O W; Epstein A L; Korsmeyer S J
Cloning the chromosomal breakpoint of t(14;18) human lymphomas: clustering around JH on chromosome 14 and near a transcriptional unit on 18.
Cell 1985;41(3):899-906.
1985: Waldmann T A; Korsmeyer S J; Bakhshi A; Arnold A; Kirsch I R
NIH conference. Molecular genetic analysis of human lymphoid neoplasms. Immunoglobulin genes and the c-myc oncogene.
Annals of internal medicine 1985;102(4):497-510.
1984: Korsmeyer S J; Bakhshi A; Arnold A; Siminovitch K A; Waldmann T A
Human B-cell precursor leukemias.
Survey and synthesis of pathology research 1984;3(6):510-9.
1983: Bakhshi A; Minowada J; Arnold A; Cossman J; Jensen J P; Whang-Peng J; Waldmann T A; Korsmeyer S J
Lymphoid blast crises of chronic myelogenous leukemia represent stages in the development of B-cell precursors.
The New England journal of medicine 1983;309(14):826-31.
1983: Korsmeyer S J; Greene W C; Cossman J; Hsu S M; Jensen J P; Neckers L M; Marshall S L; Bakhshi A; Depper J M; Leonard W J; Jaffe E S; Waldmann T A
Rearrangement and expression of immunoglobulin genes and expression of Tac antigen in hairy cell leukemia.
Proceedings of the National Academy of Sciences of the United States of America 1983;80(14):4522-6.
1983: Korsmeyer S J; Arnold A; Bakhshi A; Ravetch J V; Siebenlist U; Hieter P A; Sharrow S O; LeBien T W; Kersey J H; Poplack D G; Leder P; Waldmann T A
Immunoglobulin gene rearrangement and cell surface antigen expression in acute lymphocytic leukemias of T cell and B cell precursor origins.
The Journal of clinical investigation 1983;71(2):301-13.

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