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Jeroen Korving

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Johan H van Es; Alexander van Oudenaarden; Laura Zeinstra; Annie Ng Yee Nee; Nick Barker; Alex Gregorieff; Jeroen Korving; Anna Lyubimova; Anton C M Martens; Nobuo Sasaki; Toshiro Sato; Marc van de Wetering; Maaike van den Born; Hans Clevers
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage.
Johan H van Es; Alexander van Oudenaarden; Sylvia F Boj; Andrea Haegebarth; Shalev Itzkovitz; Bon-Kyoung Koo; Jeroen Korving; Pekka Kujala; Sylvie Robine; Maaike van den Born; Hans Clevers
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
Frank L Bos; Maresa Caunt; Henricus J Duckers; James A Ernst; Terhi Karpanen; Jeroen Korving; Joe Kowalski; Eckhard Lammert; Josi Peterson-Maduro; Lara Planas-Paz; Raymond Tong; Johan H van Es; Andreas van Impel; Stefan Schulte-Merker
CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo.

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All Publications

2012: Johan H van Es; Alexander van Oudenaarden; Laura Zeinstra; Annie Ng Yee Nee; Nick Barker; Alex Gregorieff; Jeroen Korving; Anna Lyubimova; Anton C M Martens; Nobuo Sasaki; Toshiro Sato; Marc van de Wetering; Maaike van den Born; Hans Clevers
Dll1+ secretory progenitor cells revert to stem cells upon crypt damage.
Nature cell biology 2012;14(10):1099-104.
2012: Johan H van Es; Alexander van Oudenaarden; Sylvia F Boj; Andrea Haegebarth; Shalev Itzkovitz; Bon-Kyoung Koo; Jeroen Korving; Pekka Kujala; Sylvie Robine; Maaike van den Born; Hans Clevers
A critical role for the Wnt effector Tcf4 in adult intestinal homeostatic self-renewal.
Molecular and cellular biology 2012;32(10):1918-27.
2011: Frank L Bos; Maresa Caunt; Henricus J Duckers; James A Ernst; Terhi Karpanen; Jeroen Korving; Joe Kowalski; Eckhard Lammert; Josi Peterson-Maduro; Lara Planas-Paz; Raymond Tong; Johan H van Es; Andreas van Impel; Stefan Schulte-Merker
CCBE1 is essential for mammalian lymphatic vascular development and enhances the lymphangiogenic effect of vascular endothelial growth factor-C in vivo.
Circulation research 2011;109(5):486-91.
2010: Ellen van Rooijen; Emile E Voest; Ive Logister; Jeroen Bussmann; Jeroen Korving; Fredericus J van Eeden; Rachel H Giles; Stefan Schulte-Merker
von Hippel-Lindau tumor suppressor mutants faithfully model pathological hypoxia-driven angiogenesis and vascular retinopathies in zebrafish.
Disease models & mechanisms 2010;3(5-6):343-53.
2010: Nick Barker; Meritxell Huch; Pekka Kujala; Marc van de Wetering; Hugo J Snippert; Johan H van Es; Toshiro Sato; Daniel E Stange; Harry Begthel; Maaike van den Born; Esther Danenberg; Stieneke van den Brink; Jeroen Korving; Arie Abo; Peter J Peters; Nick Wright; Richard Poulsom; Hans Clevers
Lgr5(+ve) stem cells drive self-renewal in the stomach and build long-lived gastric units in vitro.
Cell stem cell 2010;6(1):25-36.
2010: Tokameh Mahmoudi; Sylvia F Boj; Pantelis Hatzis; Vivian S W Li; Nadia Taouatas; Robert G J Vries; Hans Teunissen; Harry Begthel; Jeroen Korving; shabaz mohammed; Albert J R Heck; Hans Clevers
The leukemia-associated Mllt10/Af10-Dot1l are Tcf4/β-catenin coactivators essential for intestinal homeostasis.
PLoS biology 2010;8(11):e1000539.
2009: Alex Gregorieff; Daniel E Stange; Pekka Kujala; Harry Begthel; Maaike van den Born; Jeroen Korving; Peter J Peters; Hans Clevers
The ets-domain transcription factor Spdef promotes maturation of goblet and paneth cells in the intestinal epithelium.
Gastroenterology 2009;137(4):1333-45.e1-3.
2009: Ellen van Rooijen; Emile E Voest; Ive Logister; Jeroen Korving; Thorsten Schwerte; Stefan Schulte-Merker; Rachel H Giles; Fredericus J van Eeden
Zebrafish mutants in the von Hippel-Lindau tumor suppressor display a hypoxic response and recapitulate key aspects of Chuvash polycythemia.
Blood 2009;113(25):6449-60.
2009: Ana Faro; Sylvia F Boj; Raquel Ambrósio; Olaf van den Broek; Jeroen Korving; Hans Clevers
T-cell factor 4 (tcf7l2) is the main effector of Wnt signaling during zebrafish intestine organogenesis.
Zebrafish 2009;6(1):59-68.
2008: Harma Feitsma; Raoul V Kuiper; Jeroen Korving; Isaac J Nijman; Edwin Cuppen
Zebrafish with mutations in mismatch repair genes develop neurofibromas and other tumors.
Cancer research 2008;68(13):5059-66.
2008: Ruben van Boxtel; Pim W Toonen; Henk S van Roekel; Mark Verheul; Bart M G Smits; Jeroen Korving; Alain de Bruin; Edwin Cuppen
Lack of DNA mismatch repair protein MSH6 in the rat results in hereditary non-polyposis colorectal cancer-like tumorigenesis.
Carcinogenesis 2008;29(6):1290-7.
2007: Nick Barker; Johan H van Es; Jeroen Kuipers; Pekka Kujala; Maaike van den Born; Miranda Cozijnsen; Andrea Haegebarth; Jeroen Korving; Harry Begthel; Peter J Peters; Hans Clevers
Identification of stem cells in small intestine and colon by marker gene Lgr5.
Nature 2007;449(7165):1003-7.
2007: Linda W van Laake; Passier Robert; Jantine Monshouwer-Kloots; Arie J Verkleij; Daniel J Lips; Christian Freund; Krista den Ouden; Dorien Ward-van Oostwaard; Jeroen Korving; Leon Tertoolen; Cees J A van Echteld; Pieter A Doevendans; Christine L Mummery
Human embryonic stem cell-derived cardiomyocytes survive and mature in the mouse heart and transiently improve function after myocardial infarction.
Stem cell research 2007;1(1):9-24.
2007: Vanesa Muncan; Ana Faro; Anna-Pavlina G Haramis; Adam F L Hurlstone; Erno Wienholds; Johan H van Es; Jeroen Korving; Harry Begthel; Danica Zivkovic; Hans Clevers
T-cell factor 4 (Tcf7l2) maintains proliferative compartments in zebrafish intestine.
EMBO reports 2007;8(10):966-73.
2007: Marc Vooijs; Chin-Tong Ong; Brandon K Hadland; Stacey S Huppert; Zhenyi Liu; Jeroen Korving; Maaike van den Born; Thaddeus S Stappenbeck; Yumei Wu; Hans Clevers; Raphael Kopan
Mapping the consequence of Notch1 proteolysis in vivo with NIP-CRE.
Development (Cambridge, England) 2007;134(3):535-44.
2005: Sanne Kuijper; Harma Feitsma; Rushikesh Sheth; Jeroen Korving; Mark Reijnen; Frits Meijlink
Function and regulation of Alx4 in limb development: complex genetic interactions with Gli3 and Shh.
Developmental biology 2005;285(2):533-44.
2004: Susana M Chuva de Sousa Lopes; Alie Feijen; Jeroen Korving; Olexander Korchynskyi; Jonas Larsson; Stefan Karlsson; Peter ten Dijke; Karen M Lyons; roel goldschmeding; Pieter A Doevendans; Christine L Mummery
Connective tissue growth factor expression and Smad signaling during mouse heart development and myocardial infarction.
Developmental dynamics : an official publication of the American Association of Anatomists 2004;231(3):542-50.
2003: Adam F L Hurlstone; Anna-Pavlina G Haramis; Erno Wienholds; Harry Begthel; Jeroen Korving; Fredericus J M van Eeden; Edwin Cuppen; Danica Zivkovic; Ronald H Plasterk; Hans Clevers
The Wnt/beta-catenin pathway regulates cardiac valve formation.
Nature 2003;425(6958):633-7.
2001: Annemiek Beverdam; Antje Brouwer; Mark Reijnen; Jeroen Korving; Frits Meijlink
Severe nasal clefting and abnormal embryonic apoptosis in Alx3/Alx4 double mutant mice.
Development (Cambridge, England) 2001;128(20):3975-86.
2001: Derk ten Berge; Antje Brouwer; Jeroen Korving; Mark Reijnen; E J van Raaij; FJ Verbeek; W Gaffield; Frits Meijlink
Prx1 and Prx2 are upstream regulators of sonic hedgehog and control cell proliferation during mandibular arch morphogenesis.
Development (Cambridge, England) 2001;128(15):2929-38.
2001: AK Braat; Sandra van de Water; Jeroen Korving; Danica Zivkovic
A zebrafish vasa morphant abolishes vasa protein but does not affect the establishment of the germline.
Genesis (New York, N.Y. : 2000) 2001;30(3):183-5.
1999: Eric van den Akker; Mark Reijnen; Jeroen Korving; Antje Brouwer; Frits Meijlink; Jacqueline Deschamps
Targeted inactivation of Hoxb8 affects survival of a spinal ganglion and causes aberrant limb reflexes.
Mechanisms of development 1999;89(1-2):103-14.
1999: Kirstie A Lawson; N R Dunn; Bernard A J Roelen; Laura M Zeinstra; A M Davis; C V Wright; Jeroen Korving; B L Hogan
Bmp4 is required for the generation of primordial germ cells in the mouse embryo.
Genes & development 1999;13(4):424-36.
1998: Jeroen Charité; Wim de Graaff; D Consten; Mark Reijnen; Jeroen Korving; Jacqueline Deschamps
Transducing positional information to the Hox genes: critical interaction of cdx gene products with position-sensitive regulatory elements.
Development (Cambridge, England) 1998;125(22):4349-58.
1998: Derk ten Berge; Antje Brouwer; Jeroen Korving; J F Martin; Frits Meijlink
Prx1 and Prx2 in skeletogenesis: roles in the craniofacial region, inner ear and limbs.
Development (Cambridge, England) 1998;125(19):3831-42.