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Kenji Kosaka

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Koji Kasanuki; Omi Katsuse; Kenji Kosaka; Michiko Minegishi; Kiyoshi Sato; Takashi Togo; Hirotake Uchikado; Ryoko Yamamoto; Hiroshige Fujishiro; Yoshiko Furukawa; Shinji Higashi; Hiroaki Hino; Eizo Iseki; Heii Arai
Neuropathological investigation of the hypometabolic regions on positron emission tomography with [18F] fluorodeoxyglucose in patients with dementia with Lewy bodies.
Shinji Higashi; Darren J Moore; Michiko Minegishi; Koji Kasanuki; Hiroshige Fujishiro; Tomohiro Kabuta; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Hiroaki Hino; Kenji Kosaka; Kiyoshi Sato; Heii Arai; Keiji Wada; Eizo Iseki
Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies.
Y Heianza; S Hara; Y Arase; K Saito; K Totsuka; H Tsuji; S Kodama; S D Hsieh; Nobuhiro Yamada; Kenji Kosaka; Hirohito Sone
Low serum potassium levels and risk of type 2 diabetes: the Toranomon Hospital Health Management Center Study 1 (TOPICS 1).

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All Publications

2012: Koji Kasanuki; Omi Katsuse; Kenji Kosaka; Michiko Minegishi; Kiyoshi Sato; Takashi Togo; Hirotake Uchikado; Ryoko Yamamoto; Hiroshige Fujishiro; Yoshiko Furukawa; Shinji Higashi; Hiroaki Hino; Eizo Iseki; Heii Arai
Neuropathological investigation of the hypometabolic regions on positron emission tomography with [18F] fluorodeoxyglucose in patients with dementia with Lewy bodies.
Journal of the neurological sciences 2012;314(1-2):111-9.
2011: Shinji Higashi; Darren J Moore; Michiko Minegishi; Koji Kasanuki; Hiroshige Fujishiro; Tomohiro Kabuta; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Hiroaki Hino; Kenji Kosaka; Kiyoshi Sato; Heii Arai; Keiji Wada; Eizo Iseki
Localization of MAP1-LC3 in vulnerable neurons and Lewy bodies in brains of patients with dementia with Lewy bodies.
Journal of neuropathology and experimental neurology 2011;70(4):264-80.
2011: Y Heianza; S Hara; Y Arase; K Saito; K Totsuka; H Tsuji; S Kodama; S D Hsieh; Nobuhiro Yamada; Kenji Kosaka; Hirohito Sone
Low serum potassium levels and risk of type 2 diabetes: the Toranomon Hospital Health Management Center Study 1 (TOPICS 1).
Diabetologia 2011;54(4):762-6.
2010: Hiroshige Fujishiro; Eizo Iseki; Shinji Higashi; Koji Kasanuki; Norio Murayama; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Naoya Aoki; Kenji Kosaka; Heii Arai; Kiyoshi Sato
Distribution of cerebral amyloid deposition and its relevance to clinical phenotype in Lewy body dementia.
Neuroscience letters 2010;486(1):19-23.
2010: Katsuyuki Ukai; Koji Matsuo; Ryoichi Nakamura; Gen Sobue; Kenji Kosaka; Hiroto Shibayama; Shuji Iritani; Ryoko Ishihara; Norio Ozaki
A case of dementia with Lewy bodies that temporarily showed symptoms similar to Creutzfeldt-Jakob disease.
Psychogeriatrics : the official journal of the Japanese Psychogeriatric Society 2010;10(4):201-5.
2009: Shinji Higashi; Darren J Moore; Ryoko Yamamoto; Michiko Minegishi; Kiyoshi Sato; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Hiroaki Hino; Kenji Kosaka; Piers C Emson; Keiji Wada; Valina Dawson; Ted M Dawson; Heii Arai; Eizo Iseki
Abnormal localization of leucine-rich repeat kinase 2 to the endosomal-lysosomal compartment in lewy body disease.
Journal of neuropathology and experimental neurology 2009;68(9):994-1005.
2009: Katsuyoshi Mizukami; Toshiaki Homma; Kazutaka Aonuma; Toru Kinoshita; Kenji Kosaka; Takashi Asada
Decreased ventilatory response to hypercapnia in dementia with Lewy bodies.
Annals of neurology 2009;65(5):614-7.
2009: Ryoko Yamamoto; Eizo Iseki; Shinji Higashi; Norio Murayama; Michiko Minegishi; Kiyoshi Sato; Hiroaki Hino; Koshiro Fujisawa; Kenji Kosaka; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Mari Yoshida; Yoshio Hashizume; Heii Arai
Neuropathological investigation of regions responsible for semantic aphasia in frontotemporal lobar degeneration.
Dementia and geriatric cognitive disorders 2009;27(3):214-23.
2008: Kenji Kosaka
[Kosaka's disease].
Brain and nerve = Shinkei kenkyū no shinpo 2008;60(1):13-6.
2007: Shinji Higashi; Eizo Iseki; Ryoko Yamamoto; Michiko Minegishi; Hiroaki Hino; Koshiro Fujisawa; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Kenji Kosaka; Heii Arai
Concurrence of TDP-43, tau and alpha-synuclein pathology in brains of Alzheimer's disease and dementia with Lewy bodies.
Brain research 2007;1184():284-94.
2007: Kenji Kosaka
[Dementia with Lewy bodies--from its finding to the present, including the CDLB guideline-revised].
Rinshō shinkeigaku = Clinical neurology 2007;47(11):703-7.
2007: Shinji Higashi; Eizo Iseki; Ryoko Yamamoto; Michiko Minegishi; Hiroaki Hino; Koshiro Fujisawa; Takashi Togo; Omi Katsuse; Hirotake Uchikado; Yoshiko Furukawa; Kenji Kosaka; Heii Arai
Appearance pattern of TDP-43 in Japanese frontotemporal lobar degeneration with ubiquitin-positive inclusions.
Neuroscience letters 2007;419(3):213-8.
2007: Ryoko Yamamoto; Eizo Iseki; Norio Murayama; Michiko Minegishi; Wami Marui; Takashi Togo; Omi Katsuse; Kenji Kosaka; Masanori Kato; Takeshi Iwatsubo; Heii Arai
Correlation in Lewy pathology between the claustrum and visual areas in brains of dementia with Lewy bodies.
Neuroscience letters 2007;415(3):219-24.
2007: Kenji Kosaka
[Trends in study of Wernicke-Korsakoff syndrome].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 2007;109(6):509-15.
2006: Eizo Iseki; Ryoko Yamamoto; Norio Murayama; Michiko Minegishi; Takashi Togo; Omi Katsuse; Kenji Kosaka; Haruhiko Akiyama; Kuniaki Tsuchiya; Rohan de Silva; Lees Andrew; Heii Arai
Immunohistochemical investigation of neurofibrillary tangles and their tau isoforms in brains of limbic neurofibrillary tangle dementia.
Neuroscience letters 2006;405(1-2):29-33.
2006: Daisuke Isojima; Takashi Togo; Kenji Kosaka; Hiroshige Fujishiro; Hiroyasu Akatsu; Omi Katsuse; Shuji Iritani; Toshihiko Matsumoto; Yoshio Hirayasu
Vascular complications in dementia with Lewy bodies: a postmortem study.
Neuropathology : official journal of the Japanese Society of Neuropathology 2006;26(4):293-7.
2006: Ryoko Yamamoto; Eizo Iseki; Norio Murayama; Michiko Minegishi; Wami Marui; Takashi Togo; Omi Katsuse; Masanori Kato; Takeshi Iwatsubo; Kenji Kosaka; Heii Arai
Investigation of Lewy pathology in the visual pathway of brains of dementia with Lewy bodies.
Journal of the neurological sciences 2006;246(1-2):95-101.
2006: Satoru Mori; Etsuro Mori; Eizo Iseki; Kenji Kosaka
Efficacy and safety of donepezil in patients with dementia with Lewy bodies: preliminary findings from an open-label study.
Psychiatry and clinical neurosciences 2006;60(2):190-5.
2006: Hiroshige Fujishiro; Hiroyuki Umegaki; Daisuke Isojima; Hiroyasu Akatsu; Akihisa Iguchi; Kenji Kosaka
Depletion of cholinergic neurons in the nucleus of the medial septum and the vertical limb of the diagonal band in dementia with Lewy bodies.
Acta neuropathologica 2006;111(2):109-14.
2005: Takashi Togo; Daisuke Isojima; Hiroyasu Akatsu; Kyoko Suzuki; Hirotake Uchikado; Omi Katsuse; Eizo Iseki; Kenji Kosaka; Yoshio Hirayasu
Clinical features of argyrophilic grain disease: a retrospective survey of cases with neuropsychiatric symptoms.
The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry 2005;13(12):1083-91.
2005: Kenji Kosaka
[Progress of research on dementia with Lewy bodies].
Nihon Ronen Igakkai zasshi. Japanese journal of geriatrics 2005;42(5):475-82.
2005: Ryoko Yamamoto; Eizo Iseki; Wami Marui; Takashi Togo; Omi Katsuse; Masanori Kato; Daisuke Isojima; Hiroyasu Akatsu; Kenji Kosaka; Heii Arai
Non-uniformity in the regional pattern of Lewy pathology in brains of dementia with Lewy bodies.
Neuropathology : official journal of the Japanese Society of Neuropathology 2005;25(3):188-94.
2005: Eizo Iseki; Wami Marui; Ryoko Yamamoto; Takashi Togo; Omi Katsuse; Masanori Kato; Takeshi Iwatsubo; Kenji Kosaka; Heii Arai
The nigro-striatal and nigro-amygdaloid pathways undergo different degeneration processes in brains of dementia with Lewy bodies.
Neuroscience letters 2005;380(1-2):161-5.
2005: Kenji Kosaka
[Clinical aspects of dementing illnesses in the elderly].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 2005;107(12):1361-6.
2005: Kenji Kosaka; Eizo Iseki; Takashi Togo; Omi Katsuse
[Dementia with Lewy bodies].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 2005;107(6):529-44.
2004: Yoshiko Furukawa; Eizo Iseki; Hiroaki Hino; Toshinari Odawara; K Ikeda; Kuniaki Tsuchiya; Kenji Kosaka
Ubiquitin and ubiquitin-related proteins in the brains of patients with atypical Pick's disease without Pick bodies and dementia with motor neuron disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2004;24(4):306-14.
2004: Hiroyuki Narita; Toshinari Odawara; Eizo Iseki; Kenji Kosaka; Yoshio Hirayasu
Psychomotor retardation correlates with frontal hypoperfusion and the Modified Stroop Test in patients under 60-years-old with major depression.
Psychiatry and clinical neurosciences 2004;58(4):389-95.
2004: Wami Marui; Eizo Iseki; Masanori Kato; Hiroyasu Akatsu; Kenji Kosaka
Pathological entity of dementia with Lewy bodies and its differentiation from Alzheimer's disease.
Acta neuropathologica 2004;108(2):121-8.
2004: Takashi Togo; Haruhiko Akiyama; Eizo Iseki; Hirotake Uchikado; Hiromi Kondo; K Ikeda; Kuniaki Tsuchiya; Rohan de Silva; Andrew J Lees; Kenji Kosaka
Immunohistochemical study of tau accumulation in early stages of Alzheimer-type neurofibrillary lesions.
Acta neuropathologica 2004;107(6):504-8.
2004: Hiroyuki Narita; Toshinari Odawara; Toshihiko Matsumoto; Shigeru Kimura; Tomoki Yamada; Eizo Iseki; Kazuya Miyakawa; Hiroaki Hino; Daiji Kato; Kenji Kosaka; Yoshio Hirayasu
[A case with late-onset MELAS with hallucination and delusion].
Nō to shinkei = Brain and nerve 2004;56(4):345-9.
2004: Hirotake Uchikado; Haruhiko Akiyama; Hiromi Kondo; K Ikeda; Kuniaki Tsuchiya; Masanori Kato; Tatsuro Oda; Takashi Togo; Eizo Iseki; Kenji Kosaka
Activation of vascular endothelial cells and perivascular cells by systemic inflammation-an immunohistochemical study of postmortem human brain tissues.
Acta neuropathologica 2004;107(4):341-51.
2004: Ikuko Kishida; Chiaki Kawanishi; Taku Furuno; Daiji Kato; T Ishigami; Kenji Kosaka
Association in Japanese patients between neuroleptic malignant syndrome and functional polymorphisms of the dopamine D(2) receptor gene.
Molecular psychiatry 2004;9(3):293-8.
2004: Yoshiko Furukawa; Eizo Iseki; Hiroaki Hino; Akiko Kanai; Toshinari Odawara; Kenji Kosaka
Ubiquitin and ubiquitin-related proteins in neurons and dendrites of brains of atypical Pick's disease without Pick bodies.
Neuropathology : official journal of the Japanese Society of Neuropathology 2004;24(1):38-45.
2004: T Matsumoto; Chiaki Kawanishi; Daisuke Isojima; Eizo Iseki; Ikuko Kishida; Kenji Kosaka
Neuroleptic malignant syndrome induced by donepezil.
The international journal of neuropsychopharmacology / official scientific journal of the Collegium Internationale Neuropsychopharmacologicum (CINP) 2004;7(1):101-3.
2004: Takashi Togo; Koichi Hasegawa; Satoshi Miura; Hideki Hosojima; Katsuo Kojima; Mika Shoji; Akihiko Kase; Hirotake Uchikado; Eizo Iseki; Kenji Kosaka
Serum ghrelin concentrations in patients receiving olanzapine or risperidone.
Psychopharmacology 2004;172(2):230-2.
2004: Takashi Togo; Katsuo Kojima; Mika Shoji; Akihiko Kase; Hirotake Uchikado; Omi Katsuse; Eizo Iseki; Kenji Kosaka
Serum adiponectin concentrations during treatment with olanzapine or risperidone: a pilot study.
International clinical psychopharmacology 2004;19(1):37-40.
2003: Reiko Sakai; Michiko Aihara; Mamiko Ishiwa; Aki Negishi; Setsuko Matsukura; Kazuo Takahashi; Hirokazu Kimura; Kenji Kosaka; Zenro Ikezawa
[Natural killer cell activity among patients with atopic dermatitis].
Arerugī = [Allergy] 2003;52(11):1074-80.
2003: Hiroyuki Narita; Toshinari Odawara; Chiaki Kawanishi; Ikuko Kishida; Eizo Iseki; Kenji Kosaka
Transient lesion in the splenium of the corpus callosum, possibly due to carbamazepine.
Psychiatry and clinical neurosciences 2003;57(5):550-1.
2003: Omi Katsuse; Eizo Iseki; Tetsuaki Arai; Haruhiko Akiyama; Takashi Togo; Hirotake Uchikado; Masanori Kato; Rohan de Silva; Andrew J Lees; Kenji Kosaka
4-repeat tauopathy sharing pathological and biochemical features of corticobasal degeneration and progressive supranuclear palsy.
Acta neuropathologica 2003;106(3):251-60.
2003: Kenji Kosaka
[Diffuse Lewy body disease].
Nihon Naika Gakkai zasshi. The Journal of the Japanese Society of Internal Medicine 2003;92(8):1414-8.
2003: Omi Katsuse; Eizo Iseki; Wami Marui; Kenji Kosaka
Developmental stages of cortical Lewy bodies and their relation to axonal transport blockage in brains of patients with dementia with Lewy bodies.
Journal of the neurological sciences 2003;211(1-2):29-35.
2003: Toshinari Odawara; Kazumasa Shiozaki; Eizo Iseki; Hiroaki Hino; Kenji Kosaka
Alterations of muscarinic acetylcholine receptors in atypical Pick's disease without Pick bodies.
Journal of neurology, neurosurgery, and psychiatry 2003;74(7):965-7.
2003: Megumi Takahashi; Kenji Kosaka
Efficacy of open-system social skills training in inpatients with mood, neurotic and eating disorders.
Psychiatry and clinical neurosciences 2003;57(3):295-302.
2003: Katsuhiko Shibuya; Toshiki Uchihara; Ayako Nakamura; Miyako Ishiyama; Keiko Yamaoka; Saburo Yagishita; Kiyoshi Iwabuchi; Kenji Kosaka
Reversible conformational change of tau2 epitope on exposure to detergent in glial cytoplasmic inclusions of multiple system atrophy.
Acta neuropathologica 2003;105(5):508-14.
2003: Wami Marui; Eizo Iseki; Masanori Kato; Kenji Kosaka
Degeneration of tyrosine hydroxylase-immunoreactive neurons in the cerebral cortex and hippocampus of patients with dementia with Lewy bodies.
Neuroscience letters 2003;340(3):185-8.
2003: Wami Marui; Eizo Iseki; Naoya Sugiyama; Takehiko Matsumura; Kyoko Suzuki; Toshinari Odawara; Hiroaki Hino; Kenji Kosaka
[A Japanese family with familial Alzheimer's disease associated with presenilin 1 mutation: relationship between younger age of onset and ApoE gene polymorphism].
Nō to shinkei = Brain and nerve 2003;55(4):349-53.
2003: Kyoko Suzuki; Eizo Iseki; Omi Katsuse; Akira Yamaguchi; Kayoko Katsuyama; Ichiro Aoki; Shoji Yamanaka; Kenji Kosaka
Neuronal accumulation of alpha- and beta-synucleins in the brain of a GM2 gangliosidosis mouse model.
Neuroreport 2003;14(4):551-4.
2003: Omi Katsuse; Eizo Iseki; Kenji Kosaka
Immunohistochemical study of the expression of cytokines and nitric oxide synthases in brains of patients with dementia with Lewy bodies.
Neuropathology : official journal of the Japanese Society of Neuropathology 2003;23(1):9-15.
2003: Takashi Togo; Eizo Iseki; Mika Shoji; Ikuo Oyama; Akihiko Kase; Hirotake Uchikado; Omi Katsuse; Kenji Kosaka
Prolactin levels in schizophrenic patients receiving perospirone in comparison to risperidone.
Journal of pharmacological sciences 2003;91(3):259-62.
2003: Ikuko Kishida; Chiaki Kawanishi; Taku Furuno; Takehiko Matsumura; Hana Hasegawa; Naoya Sugiyama; Kyoko Suzuki; Yoshiteru Yamada; Kenji Kosaka
Lack of association in Japanese patients between neuroleptic malignant syndrome and the TaqI A polymorphism of the dopamine D2 receptor gene.
Psychiatric genetics 2003;13(1):55-7.
2003: Eizo Iseki; Takashi Togo; Kyoko Suzuki; Omi Katsuse; Wami Marui; Rohan de Silva; Andrew J Lees; Takayuki Yamamoto; Kenji Kosaka
Dementia with Lewy bodies from the perspective of tauopathy.
Acta neuropathologica 2003;105(3):265-70.
2003: Hideki Onishi; Masanari Onose; Tomoki Yamada; Yasuhiro Mizuno; Mizuho Ito; Hiroko Sato; Hironobu Sato; Kenji Kosaka
Post-traumatic stress disorder associated with suspected lung cancer and bereavement: 4-year follow-up and review of the literature.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2003;11(2):123-5.
2003: Kenji Kosaka
[Amnestic syndrome].
Ryōikibetsu shōkōgun shirīzu 2003;(40):131-3.
2003: Kenji Kosaka
[Pathological dream states (twilight state, delirium, amentia, dreamy state, drunkenness)].
Ryōikibetsu shōkōgun shirīzu 2003;(40):127-30.
2003: Kenji Kosaka
[Clouding of consciousness].
Ryōikibetsu shōkōgun shirīzu 2003;(40):123-6.
2003: Toshinari Odawara; Eizo Iseki; Akiko Kanai; Tetsuaki Arai; Toshio Katsuragi; Hiroaki Hino; Yoshiko Furukawa; Masanori Kato; Takayuki Yamamoto; Kenji Kosaka
Clinicopathological study of two subtypes of Pick's disease in Japan.
Dementia and geriatric cognitive disorders 2003;15(1):19-25.
2002: Akihiko Nunomura; Shigeru Chiba; Kenji Kosaka; Atsushi Takeda; Rudy J Castellani; Mark A. Smith; George Perry
Neuronal RNA oxidation is a prominent feature of dementia with Lewy bodies.
Neuroreport 2002;13(16):2035-9.
2002: Hirotake Uchikado; Eizo Iseki; Kuniaki Tsuchiya; Takashi Togo; Omi Katsuse; Kenji Uéda; Masanori Kato; Kenji Kosaka
Dementia with Lewy bodies showing advanced Lewy pathology but minimal Alzheimer pathology--Lewy pathology causes neuronal loss inducing progressive dementia.
Clinical neuropathology 2002;21(6):269-77.
2002: Toshinari Odawara; Eizo Iseki; Yoshiko Furukawa; Kyoko Suzuki; Hiroaki Hino; Kenji Kosaka
Degeneration of Pick bodies visualized by methenamine-silver staining and immunohistochemistry.
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(3):180-5.
2002: Noriko Takayama; Eizo Iseki; Takayuki Yamamoto; Kenji Kosaka
Regional quantitative study of formation process of neurofibrillary tangles in the hippocampus of non-demented elderly brains: comparison with late-onset Alzheimer's disease brains.
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(3):147-53.
2002: Eizo Iseki; Noriko Takayama; Yoshiko Furukawa; Wami Marui; Toshiki Nakai; Satoshi Miura; Kenji Uéda; Kenji Kosaka
Immunohistochemical study of synphilin-1 in brains of patients with dementia with Lewy bodies - synphilin-1 is non-specifically implicated in the formation of different neuronal cytoskeletal inclusions.
Neuroscience letters 2002;326(3):211-5.
2002: K Ikeda; Haruhiko Akiyama; Tetsuaki Arai; Hideki Ueno; Kuniaki Tsuchiya; Kenji Kosaka
Morphometrical reappraisal of motor neuron system of Pick's disease and amyotrophic lateral sclerosis with dementia.
Acta neuropathologica 2002;104(1):21-8.
2002: Masanari Onose; Chiaki Kawanishi; Hideki Onishi; Tomoki Yamada; M Itoh; Kenji Kosaka; J Taguchi; S Fujisawa; H Kanamori
Neuroleptic malignant syndrome following BMT.
Bone marrow transplantation 2002;29(9):803-4.
2002: Wami Marui; Eizo Iseki; Toshiki Nakai; Satoshi Miura; Masanori Kato; Kenji Uéda; Kenji Kosaka
Progression and staging of Lewy pathology in brains from patients with dementia with Lewy bodies.
Journal of the neurological sciences 2002;195(2):153-9.
2002: Eizo Iseki; Noriko Takayama; Wami Marui; Kenji Uéda; Kenji Kosaka
Relationship in the formation process between neurofibrillary tangles and Lewy bodies in the hippocampus of dementia with Lewy bodies brains.
Journal of the neurological sciences 2002;195(1):85-91.
2002: Eizo Iseki; Sadaharu Tsunoda; Kyoko Suzuki; Noriko Takayama; Hiroyasu Akatsu; Takayuki Yamamoto; Kenji Kosaka
Regional quantitative analysis of NFT in brains of non-demented elderly persons: comparisons with findings in brains of late-onset Alzheimer's disease and limbic NFT dementia.
Neuropathology : official journal of the Japanese Society of Neuropathology 2002;22(1):34-9.
2002: Takashi Togo; Haruhiko Akiyama; Eizo Iseki; Hiromi Kondo; K Ikeda; Masanori Kato; Tatsuro Oda; Kuniaki Tsuchiya; Kenji Kosaka
Occurrence of T cells in the brain of Alzheimer's disease and other neurological diseases.
Journal of neuroimmunology 2002;124(1-2):83-92.
2002: Chiaki Kawanishi; Taku Furuno; Ikuko Kishida; Takehiko Matsumura; Kenji Kosaka
A patient with treatment-resistant schizophrenia and cytochrome P4502D6 gene duplication.
Clinical genetics 2002;61(2):152-4.
2001: Kazumasa Shiozaki; Eizo Iseki; Hiroaki Hino; Kenji Kosaka
Distribution of m1 muscarinic acetylcholine receptors in the hippocampus of patients with Alzheimer's disease and dementia with Lewy bodies-an immunohistochemical study.
Journal of the neurological sciences 2001;193(1):23-8.
2001: Omi Katsuse; Eizo Iseki; Kyoko Suzuki; Kenji Kosaka
Frequency and distribution of TUNEL-positive neurons in brains of dementia with Lewy bodies: comparison with those in brains of Alzheimer's disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2001;21(4):272-7.
2001: Eizo Iseki; T Matsumura; Wami Marui; H Hino; Toshinari Odawara; N Sugiyama; K Suzuki; H Sawada; T Arai; Kenji Kosaka
Familial frontotemporal dementia and parkinsonism with a novel N296H mutation in exon 10 of the tau gene and a widespread tau accumulation in the glial cells.
Acta neuropathologica 2001;102(3):285-92.
2001: Kazuhiro Niizato; Kuniaki Tsuchiya; Ryosuke Nakamura; Shuji Iritani; K Ikeda; Kenji Kosaka
[An autopsied case of presenile dementia with tangles].
Nō to shinkei = Brain and nerve 2001;53(7):659-64.
2001: Eizo Iseki; Masanori Kato; Wami Marui; Kenji Uéda; Kenji Kosaka
A neuropathological study of the disturbance of the nigro-amygdaloid connections in brains from patients with dementia with Lewy bodies.
Journal of the neurological sciences 2001;185(2):129-34.
2001: Taku Furuno; Chiaki Kawanishi; Eizo Iseki; Hideki Onishi; Naoya Sugiyama; Kyoko Suzuki; Kenji Kosaka
No evidence of an association between CYP2D6 polymorphisms among Japanese and dementia with Lewy bodies.
Psychiatry and clinical neurosciences 2001;55(2):89-92.
2001: J Fujishiro; T Imanishi; J Baba; Kenji Kosaka
Comparison of noradrenergic and serotonergic antidepressants in reducing immobility time in the tail suspension test.
Japanese journal of pharmacology 2001;85(3):327-30.
2001: Takashi Togo; Eizo Iseki; Wami Marui; Haruhiko Akiyama; Kenji Uéda; Kenji Kosaka
Glial involvement in the degeneration process of Lewy body-bearing neurons and the degradation process of Lewy bodies in brains of dementia with Lewy bodies.
Journal of the neurological sciences 2001;184(1):71-5.
2001: H Hino; Haruhiko Akiyama; Eizo Iseki; Masanori Kato; H Kondo; K Ikeda; Kenji Kosaka
Immunohistochemical localization of plasminogen activator inhibitor-1 in rat and human brain tissues.
Neuroscience letters 2001;297(2):105-8.
2001: T Matsumura; H Osaka; K Inoue; N Sugiyama; H Onishi; Y Yamada; M Hayashi; Kenji Kosaka
A novel deletion (c663delC) at exon 5 of the proteolipid protein gene in Pelizaeus-Merzbacher disease.
Human mutation 2001;17(1):80.
2000: Takashi Togo; Haruhiko Akiyama; Hiromi Kondo; K Ikeda; Masanori Kato; Eizo Iseki; Kenji Kosaka
Expression of CD40 in the brain of Alzheimer's disease and other neurological diseases.
Brain research 2000;885(1):117-21.
2000: Chiaki Kawanishi; Taku Furuno; Hideki Onishi; Naoya Sugiyama; Kyoko Suzuki; Takehiko Matsumura; T Ishigami; Kenji Kosaka
Lack of association in Japanese patients between neuroleptic malignant syndrome and a debrisoquine 4-hydroxylase genotype with low enzyme activity.
Psychiatric genetics 2000;10(3):145-7.
2000: F Li; Eizo Iseki; Masanori Kato; Y Adachi; M Akagi; Kenji Kosaka
An autopsy case of Alzheimer's disease presenting with primary progressive aphasia: a clinicopathological and immunohistochemical study.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20(3):239-45.
2000: Kenji Kosaka
Diffuse Lewy body disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20 Suppl():S73-8.
2000: Eizo Iseki; Wami Marui; H Sawada; Kenji Uéda; Kenji Kosaka
Accumulation of human alpha-synuclein in different cytoskeletons in Lewy bodies in brains of dementia with Lewy bodies.
Neuroscience letters 2000;290(1):41-4.
2000: Hideki Onishi; Akira Miyashita; Kenji Kosaka
A manic episode associated with bereavement in a patient with lung cancer. A case report.
Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer 2000;8(4):339-40.
2000: Eizo Iseki; Wami Marui; Haruhiko Akiyama; Kenji Uéda; Kenji Kosaka
Degeneration process of Lewy bodies in the brains of patients with dementia with Lewy bodies using alpha-synuclein-immunohistochemistry.
Neuroscience letters 2000;286(1):69-73.
2000: Mikio Shoji; Yasuo Harigaya; A Sasaki; K Uéda; Koichi Ishiguro; Etsuro Matsubara; Mitsunori Watanabe; Masaki Ikeda; Mitsuyasu Kanai; Yasushi Tomidokoro; M Shizuka; Masakuni Amari; Kenji Kosaka; Yoichi Nakazato; Koichi Okamoto; Shunsaku Hirai
Accumulation of NACP/alpha-synuclein in lewy body disease and multiple system atrophy.
Journal of neurology, neurosurgery, and psychiatry 2000;68(5):605-8.
2000: M Takahashi; Eizo Iseki; Kenji Kosaka
Cyclin-dependent kinase 5 (Cdk5) associated with Lewy bodies in diffuse Lewy body disease.
Brain research 2000;862(1-2):253-6.
2000: Wami Marui; Eizo Iseki; Kenji Uéda; Kenji Kosaka
Occurrence of human alpha-synuclein immunoreactive neurons with neurofibrillary tangle formation in the limbic areas of patients with Alzheimer's disease.
Journal of the neurological sciences 2000;174(2):81-4.
2000: Kenji Kosaka; Eizo Iseki
Clinicopathological studies on diffuse Lewy body disease.
Neuropathology : official journal of the Japanese Society of Neuropathology 2000;20(1):1-7.
2000: M Takahashi; Eizo Iseki; Kenji Kosaka
Cdk5 and munc-18/p67 co-localization in early stage neurofibrillary tangles-bearing neurons in Alzheimer type dementia brains.
Journal of the neurological sciences 2000;172(1):63-9.
1999: T Miyakawa; Eizo Iseki; M Shiraishi; S Fujiwara; Kenji Kosaka
[An autopsied case of subacute progressive dementia with flactuated disturbance of consciousness, myoclonus and periodic synchronous discharges on EEGs].
Nō to shinkei = Brain and nerve 1999;51(11):969-74.
1999: Toshiki Nakai; A Yamasaki; M Sakaguchi; Kenji Kosaka; K Mihara; Y Amaya; S Miura
Membrane topology of Alzheimer's disease-related presenilin 1. Evidence for the existence of a molecular species with a seven membrane-spanning and one membrane-embedded structure.
The Journal of biological chemistry 1999;274(33):23647-58.
1999: Kenji Kosaka
[Non-Alzheimer degenerative dementias].
Nō to shinkei = Brain and nerve 1999;51(8):691-7.
1999: Kazumasa Shiozaki; Eizo Iseki; H Uchiyama; Y Watanabe; T Haga; K Kameyama; T Ikeda; Takayuki Yamamoto; Kenji Kosaka
Alterations of muscarinic acetylcholine receptor subtypes in diffuse lewy body disease: relation to Alzheimer's disease.
Journal of neurology, neurosurgery, and psychiatry 1999;67(2):209-13.
1999: Eizo Iseki; Wami Marui; Kenji Kosaka; Kenji Uéda
Frequent coexistence of Lewy bodies and neurofibrillary tangles in the same neurons of patients with diffuse Lewy body disease.
Neuroscience letters 1999;265(1):9-12.
1999: Kenji Kosaka; Eizo Iseki; Heii Arai
Recent advances in dementia research in Japan: Alzheimer-type dementia.
Psychiatry and clinical neurosciences 1999;53(1):1-10.
1999: Naoya Sugiyama; Kyoko Suzuki; Takehiko Matsumura; Chiaki Kawanishi; Hideki Onishi; Y Yamada; Eizo Iseki; Kenji Kosaka
A novel missense mutation (G209R) in exon 8 of the presenilin 1 gene in a Japanese family with presenile familial Alzheimer's disease. Mutation in brief no. 254. Online.
Human mutation 1999;14(1):90.
1999: Kenji Kosaka
[Diffuse Lewy body disease].
Ryōikibetsu shōkōgun shirīzu 1999;(27 Pt 2):82-5.
1999: Hitoshi Osaka; Chiaki Kawanishi; K Inoue; Hideki Onishi; T Kobayashi; Naoya Sugiyama; Kenji Kosaka; A Nezu; K Fujii; Kanji Sugita; K Kodama; K Murayama; S Murayama; I Kanazawa; S Kimura
Pelizaeus-Merzbacher disease: three novel mutations and implication for locus heterogeneity.
Annals of neurology 1999;45(1):59-64.
1999: K Ikeda; Haruhiko Akiyama; Tetsuaki Arai; T Oda; M Kato; E Iseki; Kenji Kosaka; K Wakabayashi; H Takahashi
Clinical aspects of 'senile dementia of the tangle type'-- a subset of dementia in the senium separable from late-onset Alzheimer's disease.
Dementia and geriatric cognitive disorders 1999;10(1):6-11.
1998: Eizo Iseki; Wami Marui; Kenji Kosaka; Haruhiko Akiyama; K Ueda; Takeshi Iwatsubo
Degenerative terminals of the perforant pathway are human alpha-synuclein-immunoreactive in the hippocampus of patients with diffuse Lewy body disease.
Neuroscience letters 1998;258(2):81-4.
1998: H Kishimoto; K Yamada; E Iseki; Kenji Kosaka; T Okoshi
Brain imaging of affective disorders and schizophrenia.
Psychiatry and clinical neurosciences 1998;52 Suppl():S212-4.
1998: T Miyakawa; K Inoue; Eizo Iseki; C Kawanishi; N Sugiyama; H Onishi; Y Yamada; K Suzuki; K Iwabuchi; Kenji Kosaka
Japanese Creutzfeldt-Jakob disease patients exhibiting high incidence of the E200K PRNP mutation and located in the basin of a river.
Neurological research 1998;20(8):684-8.
1998: Eizo Iseki; Kenji Kosaka
[Hippocampal pathology in diffuse Lewy body disease].
Nō to shinkei = Brain and nerve 1998;50(10):907-12.
1998: Chiaki Kawanishi; Y Shimoda; J Fujimaki; Hideki Onishi; Kyoko Suzuki; Tokiji Hanihara; Naoya Sugiyama; Kenji Kosaka
Mutation involving cytochrome P450IID6 in two Japanese patients with neuroleptic malignant syndrome.
Journal of the neurological sciences 1998;160(1):102-4.
1998: Chiaki Kawanishi; Tokiji Hanihara; Y Shimoda; Kyoko Suzuki; Naoya Sugiyama; Hideki Onishi; T Miyakawa; Yoshiteru Yamada; Kenji Kosaka
Lack of association between neuroleptic malignant syndrome and polymorphisms in the 5-HT1A and 5-HT2A receptor genes.
The American journal of psychiatry 1998;155(9):1275-7.
1998: Eizo Iseki; F Li; Toshinari Odawara; Hiroaki Hino; Kyoko Suzuki; Kenji Kosaka; Haruhiko Akiyama; K Ikeda; Masanori Kato
Ubiquitin-immunohistochemical investigation of atypical Pick's disease without Pick bodies.
Journal of the neurological sciences 1998;159(2):194-201.
1998: Kenji Kosaka; Eizo Iseki
Recent advances in dementia research in Japan: non-Alzheimer-type degenerative dementias.
Psychiatry and clinical neurosciences 1998;52(4):367-73.
1998: F Li; Eizo Iseki; Toshinari Odawara; Kenji Kosaka; Saburo Yagishita; Naoji Amano
Regional quantitative analysis of tau-positive neurons in progressive supranuclear palsy: comparison with Alzheimer's disease.
Journal of the neurological sciences 1998;159(1):73-81.
1998: Y Maruyama; Hideki Onishi; T Miura; Kenji Kosaka
A case of depressive disorder with neuronal heterotopia.
Psychiatry and clinical neurosciences 1998;52(3):361-2.
1998: Hideki Onishi; Tokiji Hanihara; Naoya Sugiyama; Chiaki Kawanishi; Eizo Iseki; Y Maruyama; Yoshiteru Yamada; Kenji Kosaka; Saburo Yagishita; H Sekihara; S Satoh
Pancreatic exocrine dysfunction associated with mitochondrial tRNA(Leu)(UUR) mutation.
Journal of medical genetics 1998;35(3):255-7.
1998: Toshinari Odawara; Eizo Iseki; F Li; Kenji Kosaka; K Ikeda
Heparan sulfate proteoglycans recognize ghost Pick bodies.
Neuroscience letters 1998;242(2):120-2.
1998: T Matsumura; Hitoshi Osaka; Naoya Sugiyama; Chiaki Kawanishi; Y Maruyama; K Suzuki; Hideki Onishi; Y Yamada; M Morita; M Aoki; Kenji Kosaka
Novel acceptor splice site mutation in the invariant AG of intron 6 of alpha-galactosidase A gene, causing Fabry disease. Mutations in brief no. 146. Online.
Human mutation 1998;11(6):483.
1998: Kenji Kosaka
Diffuse Lewy body disease.
Internal medicine (Tokyo, Japan) 1998;37(1):6-10.
1997: Eizo Iseki; F Li; Toshinari Odawara; Kenji Kosaka
Hippocampal pathology in diffuse Lewy body disease using ubiquitin immunohistochemistry.
Journal of the neurological sciences 1997;149(2):165-9.
1997: Hideki Onishi; Chiaki Kawanishi; T Iwasawa; Hitoshi Osaka; Tokiji Hanihara; K Inoue; Yoshiteru Yamada; Kenji Kosaka
Depressive disorder due to mitochondrial transfer RNALeu(UUR) mutation.
Biological psychiatry 1997;41(11):1137-9.
1997: Tokiji Hanihara; K Inoue; Chiaki Kawanishi; Naoya Sugiyama; T Miyakawa; Hideki Onishi; Yoshiteru Yamada; Hitoshi Osaka; Kenji Kosaka; K Iwabuchi; M Owada
6-Pyruvoyl-tetrahydropterin synthase deficiency with generalized dystonia and diurnal fluctuation of symptoms: a clinical and molecular study.
Movement disorders : official journal of the Movement Disorder Society 1997;12(3):408-11.
1997: H Hino; K Mori; Y Yoshihara; Eizo Iseki; Haruhiko Akiyama; T Nishimura; K Ikeda; Kenji Kosaka
Reduction of telencephalin immunoreactivity in the brain of patients with Alzheimer's disease.
Brain research 1997;753(2):353-7.
1997: Eizo Iseki; F Li; Kenji Kosaka
Close relationship between spongiform change and ubiquitin-positive granular structures in diffuse Lewy body disease.
Journal of the neurological sciences 1997;146(1):53-7.
1997: Chiaki Kawanishi; Tokiji Hanihara; Y Maruyama; Takehiko Matsumura; Hideki Onishi; K Inoue; Naoya Sugiyama; Kyoko Suzuki; Yoshiteru Yamada; Kenji Kosaka
Neuroleptic malignant syndrome and hydroxylase gene mutations: no association with CYP2D6A or CYP2D6B.
Psychiatric genetics 1997;7(3):127-9.
1997: Chiaki Kawanishi; Hitoshi Osaka; K Owa; K Inoue; T Miyakawa; Hideki Onishi; Y Yamada; Kyoko Suzuki; S Kimura; Kenji Kosaka
A new missense mutation in exon 6 of the proteolipid protein gene in a patient with Pelizaeus-Merzbacher disease.
Human mutation 1997;9(5):475-6.
1997: Chiaki Kawanishi; Hitoshi Osaka; K Inoue; Hideki Onishi; Y Yamada; Kenji Kosaka
A new restriction-site polymorphism in the human proteolipid protein gene.
Clinical genetics 1997;51(1):75.
1997: Toshinari Odawara; Eizo Iseki; Kenji Kosaka
[Parkinsonism in Alzheimer's disease].
Nihon rinsho. Japanese journal of clinical medicine 1997;55(1):149-52.
1997: K Inoue; Hitoshi Osaka; Chiaki Kawanishi; Naoya Sugiyama; M Ishii; Kanji Sugita; Y Yamada; Kenji Kosaka
Mutations in the proteolipid protein gene in Japanese families with Pelizaeus-Merzbacher disease.
Neurology 1997;48(1):283-5.
1996: T Katsuragi; Eizo Iseki; Kenji Kosaka; T Nishimura; Haruhiko Akiyama; K Ikeda; M Kato
Immunohistochemical investigation of human leukocyte antigen (HLA)-DR-positive astrocytes in adrenoleukodystrophy brain.
Neuroscience letters 1996;219(3):207-10.
1996: F Li; Eizo Iseki; Kenji Kosaka; T Nishimura; Haruhiko Akiyama; M Kato
Progressive supranuclear palsy with fronto-temporal atrophy and various tau-positive abnormal structures.
Clinical neuropathology 1996;15(6):319-23.
1996: K Ikeda; Haruhiko Akiyama; Shuji Iritani; K Kase; Tetsuaki Arai; Kazuhiro Niizato; Noriomi Kuroki; Kenji Kosaka
Corticobasal degeneration with primary progressive aphasia and accentuated cortical lesion in superior temporal gyrus: case report and review.
Acta neuropathologica 1996;92(5):534-9.
1996: Eizo Iseki; Toshinari Odawara; F Li; Kenji Kosaka; T Nishimura; Haruhiko Akiyama; K Ikeda
Age-related ubiquitin-positive granular structures in non-demented subjects and neurodegenerative disorders.
Journal of the neurological sciences 1996;142(1-2):25-9.
1996: Kenji Kosaka; Eizo Iseki
Dementia with Lewy bodies.
Current opinion in neurology 1996;9(4):271-5.
1996: Kenji Kosaka; K Ikeda
Diffuse neurofibrillary tangles with calcification in a non-demented woman.
Journal of neurology, neurosurgery, and psychiatry 1996;61(1):116.
1996: K Inoue; Hitoshi Osaka; Naoya Sugiyama; Chiaki Kawanishi; Hideki Onishi; Atsuo Nezu; K Kimura; Y Yamada; Kenji Kosaka
A duplicated PLP gene causing Pelizaeus-Merzbacher disease detected by comparative multiplex PCR.
American journal of human genetics 1996;59(1):32-9.
1996: K Inoue; Tokiji Hanihara; Y Yamada; Kenji Kosaka; T Katsuragi; K Iwabuchi
Clinical and genetic evaluation of Japanese autosomal dominant cerebellar ataxias; is Machado-Joseph disease common in the Japanese?
Journal of neurology, neurosurgery, and psychiatry 1996;60(6):697-8.
1996: Katsuyoshi Mizukami; M Sasaki; H Shiraishi; K Ikeda; Kenji Kosaka
A neuropathologic study of long-term, Economo-type postencephalitic parkinsonism with a prolonged clinical course.
Psychiatry and clinical neurosciences 1996;50(2):79-83.
1996: Chiaki Kawanishi; Kyoko Suzuki; Toshinari Odawara; Eizo Iseki; Hideki Onishi; T Miyakawa; Y Yamada; Kenji Kosaka; N Kondo; T Yamamoto
Neuropathological evaluation and apolipoprotein E gene polymorphism analysis in diffuse Lewy body disease.
Journal of the neurological sciences 1996;136(1-2):140-2.
1996: Chiaki Kawanishi; Naoya Sugiyama; Hitoshi Osaka; K Inoue; Kyoko Suzuki; Hideki Onishi; Y Yamada; Atsuo Nezu; Seiji Kimura; Kenji Kosaka
Pelizaeus-Merzbacher disease: a novel mutation in the 5'-untranslated region of the proteolipid protein gene.
Human mutation 1996;7(4):355-7.
1995: T Nishimura; K Ikeda; Haruhiko Akiyama; H Kondo; M Kato; F Li; Eizo Iseki; Kenji Kosaka
Immunohistochemical investigation of tau-positive structures in the cerebral cortex of patients with progressive supranuclear palsy.
Neuroscience letters 1995;201(2):123-6.
1995: Kenji Kosaka
[Diffuse Lewy body disease].
Rinshō shinkeigaku = Clinical neurology 1995;35(12):1455-6.
1995: T Nishimura; Haruhiko Akiyama; S Yonehara; H Kondo; K Ikeda; M Kato; Eizo Iseki; Kenji Kosaka
Fas antigen expression in brains of patients with Alzheimer-type dementia.
Brain research 1995;695(2):137-45.
1995: T Uchihara; H Kondo; K Ikeda; Kenji Kosaka
Alzheimer-type pathology in melanin-bleached sections of substantia nigra.
Journal of neurology 1995;242(8):485-9.
1995: Toshinari Odawara; Eizo Iseki; Kenji Kosaka; Haruhiko Akiyama; K Ikeda; Takayuki Yamamoto
Investigation of tau-2 positive microglia-like cells in the subcortical nuclei of human neurodegenerative disorders.
Neuroscience letters 1995;192(3):145-8.
1994: Chie Haga; K Ikeda; K Iwabuchi; Haruhiko Akiyama; H Kondoh; Kenji Kosaka
Methenamine-silver staining: a simple and sensitive staining method for senile plaques and neurofibrillary tangles.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1994;69(5):295-300.
1994: K Ohara; N Kondo; D Xie; K Tanabe; T Yamamoto; Kenji Kosaka; K Miyasato; K Ohara
Normal sequences of muscarinic acetylcholine receptors (m1 and m2) in patients with Alzheimer's disease and vascular dementia.
Neuroscience letters 1994;178(1):23-6.
1994: Kenji Kosaka
Diffuse neurofibrillary tangles with calcification: a new presenile dementia.
Journal of neurology, neurosurgery, and psychiatry 1994;57(5):594-6.
1994: T Miyauchi; H Hagimoto; M Ishii; S Endo; K Tanaka; S Kajiwara; K Endo; A Kajiwara; Kenji Kosaka
Quantitative EEG in patients with presenile and senile dementia of the Alzheimer type.
Acta neurologica Scandinavica 1994;89(1):56-64.
1993: T Nishinaka; D Iwata; S Shimada; Kenji Kosaka; Y Suzuki
Anti-ganglioside GD1a monoclonal antibody recognizes senile plaques in the brains of patients with Alzheimer-type dementia.
Neuroscience research 1993;17(2):171-6.
1993: K Iwabuchi; S Yagishita; N Amano; H Nagatomo; Kyoko Suzuki; Kenji Kosaka
[An autopsied Japanese case of hereditary olivo-ponto-cerebellar atrophy compatible with the original one of Menzel's report (1891)].
Nō to shinkei = Brain and nerve 1993;45(4):381-7.
1993: K Iwabuchi; T Kogure; T Oda; Y Kato; K Ohtani; K Endo; Kenji Kosaka; N Amano; S Yagishita
[Some problems on the clinical phenotype of Machado-Joseph disease in relation between their ages at onset].
Nō to shinkei = Brain and nerve 1993;45(3):246-54.
1993: H Kondoh; M Matsushita; Kenji Kosaka; N Miyazaki
Staining senile plaques using Bodian's method modified with methenamine.
Biotechnic & histochemistry : official publication of the Biological Stain Commission 1993;68(2):113-6.
1993: Hideki Onishi; K Inoue; Hitoshi Osaka; Seiji Kimura; H Nagatomo; Tokiji Hanihara; S Kawamoto; K Okuda; Y Yamada; Kenji Kosaka
Mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes (MELAS) and diabetes mellitus: molecular genetic analysis and family study.
Journal of the neurological sciences 1993;114(2):205-8.
1993: Kenji Kosaka
Dementia and neuropathology in Lewy body disease.
Advances in neurology 1993;60():456-63.
1992: Takahiro Jimi; Yoshihiro Wakayama; Seiji Shibuya; H Nakata; T Tomaru; Y Takahashi; Kenji Kosaka; T Asano; K Kato
High levels of nervous system-specific proteins in cerebrospinal fluid in patients with early stage Creutzfeldt-Jakob disease.
Clinica chimica acta; international journal of clinical chemistry 1992;211(1-2):37-46.
1992: Katsuyoshi Mizukami; M Sasaki; H Shiraishi; J Koizumi; T Ogata; Kenji Kosaka
An autopsied case of dentatorubropallidoluysian atrophy with atypical pathological features.
The Japanese journal of psychiatry and neurology 1992;46(3):749-54.
1992: M Takahashi; O Hasegawa; H Fujita; H Kishimoto; Kenji Kosaka
[A case of general paresis with marked improvement of cerebral blood flow after antiluetic therapy--case report].
Nō to shinkei = Brain and nerve 1992;44(7):645-8.
1992: Toshinari Odawara; Eizo Iseki; S Yagishita; N Amano; Kenji Kosaka; K Hasegawa; Y Matsuda; H Kowa
An autopsied case of juvenile parkinsonism and dementia, with a widespread occurrence of Lewy bodies and spheroids.
Clinical neuropathology 1992;11(3):131-4.
1992: K Ikeda; Chie Haga; S Oyanagi; Shuji Iritani; Kenji Kosaka
Ultrastructural and immunohistochemical study of degenerate neurite-bearing ghost tangles.
Journal of neurology 1992;239(4):191-4.
1992: Katsuyoshi Mizukami; M Sasaki; Toshihito Suzuki; H Shiraishi; J Koizumi; N Ohkoshi; T Ogata; N Mori; S Ban; Kenji Kosaka
Central nervous system changes in mitochondrial encephalomyopathy: light and electron microscopic study.
Acta neuropathologica 1992;83(4):449-52.
1992: N Arai; S Yagishita; K Misugi; M Oda; Kenji Kosaka; T Mizutani; Yoshio Morimatsu
Peculiar axonal debris with subsequent astrocytic response (foamy spheroid body). A topographic, light microscopic, immunohistochemical and electron microscopic study.
Virchows Archiv. A, Pathological anatomy and histopathology 1992;420(3):243-52.
1992: Heii Arai; Y Ichimiya; Kenji Kosaka; T Moroji; R Iizuka
Neurotransmitter changes in early- and late-onset Alzheimer-type dementia.
Progress in neuro-psychopharmacology & biological psychiatry 1992;16(6):883-90.
1992: T Uchihara; H Kondo; Kenji Kosaka; H Tsukagoshi
Selective loss of nigral neurons in Alzheimer's disease: a morphometric study.
Acta neuropathologica 1992;83(3):271-6.
1991: K Iwabuchi; S Yagishita; N Amano; Kenji Kosaka
[A new type of complicated form of hereditary spastic paraplegia showing mental deterioration, quadriplegia with muscular atrophy, sensory disturbance, extrapyramidal disorders, and epilepsy].
Rinshō shinkeigaku = Clinical neurology 1991;31(9):945-52.
1991: Heii Arai; I Noguchi; Y Makino; Kenji Kosaka; C W Heizmann; R Iizuka
Parvalbumin-immunoreactive neurons in the cortex in Pick's disease.
Journal of neurology 1991;238(4):200-2.
1991: Kenji Kosaka; K Ikeda; K Kobayashi; P Mehraein
Striatopallidonigral degeneration in Pick's disease: a clinicopathological study of 41 cases.
Journal of neurology 1991;238(3):151-60.
1991: K Iwabuchi; Kenji Kosaka; Chie Haga; K Tuchiya; N Amano; K Itoh; S Yagishita; Y Mizutani
[Study on argyrophilic inclusions of multisystem atrophy (Oppenheimer)].
Nō to shinkei = Brain and nerve 1991;43(6):561-8.
1990: K Tsuchiya; Kenji Kosaka
Neuropathological study of the amygdala in presenile Alzheimer's disease.
Journal of the neurological sciences 1990;100(1-2):165-73.
1990: K Iwabuchi; S Yagishita; N Amano; S Yokoi; H Honda; T Tanabe; J Kinoshita; Kenji Kosaka
[An autopsy case of complicated form of spastic paraplegia with amyotrophy, mental deficiency, sensory impairment, and parkinsonism].
Nō to shinkei = Brain and nerve 1990;42(11):1075-83.
1990: N Iwamoto; Y Suzuki; Y Makino; C Haga; Kenji Kosaka; R Iizuka
Cell membrane changes in brains manifesting senile plaques: an immunohistochemical study of GM1 membranous ganglioside.
Brain research 1990;522(1):152-6.
1990: T Kito-Yamashita; Chie Haga; K Hirai; T Uemura; H Kondo; Kenji Kosaka
Localization of serotonin immunoreactivity in cephalopod visual system.
Brain research 1990;521(1-2):81-8.
1990: Kenji Kosaka
Diffuse Lewy body disease in Japan.
Journal of neurology 1990;237(3):197-204.
1990: K Ikeda; Chie Haga; Kenji Kosaka
Light and electron microscopic examination of amyloid-rich primitive plaques: comparison with diffuse plaques.
Journal of neurology 1990;237(2):88-93.
1990: T Uchihara; K Tsuchiya; Kenji Kosaka
Selective loss of nigral neurons in Pick's disease: a morphometric study.
Acta neuropathologica 1990;81(2):155-61.
1990: Eizo Iseki; M Matsushita; Kenji Kosaka; K Suzuki; N Amano; A Saito
Morphological characteristics of senile plaques in familial Alzheimer's disease.
Acta neuropathologica 1990;80(3):227-32.
1990: Haruyasu Yamaguchi; C Haga; Shunsaku Hirai; Yoichi Nakazato; Kenji Kosaka
Distinctive, rapid, and easy labeling of diffuse plaques in the Alzheimer brains by a new methenamine silver stain.
Acta neuropathologica 1990;79(5):569-72.
1989: R Okiyama; K Tsuchiya; T Furukawa; H Tsukagoshi; Kenji Kosaka
[An autopsy case of panencephalopathic type of Creutzfeldt-Jakob disease: an early clinical sign documented by magnetic resonance imaging].
Rinshō shinkeigaku = Clinical neurology 1989;29(8):1048-51.
1989: Heii Arai; N Sagi; I Noguchi; S Haga; T Ishii; Y Makino; Kenji Kosaka
An immunohistochemical study of beta-protein in Alzheimer-type dementia brains.
Journal of neurology 1989;236(4):214-7.
1989: N Iwamoto; K Kobayashi; Kenji Kosaka
The formation of prostaglandins in the postmortem cerebral cortex of Alzheimer-type dementia patients.
Journal of neurology 1989;236(2):80-4.
1989: K Mizukami; Kenji Kosaka
Neuropathological study on the nucleus basalis of Meynert in Pick's disease.
Acta neuropathologica 1989;78(1):52-6.
1989: Eizo Iseki; M Matsushita; Kenji Kosaka; H Kondo; T Ishii; N Amano
Distribution and morphology of brain stem plaques in Alzheimer's disease.
Acta neuropathologica 1989;78(2):131-6.
1989: K Ikeda; Chie Haga; Kenji Kosaka; S Oyanagi
Senile plaque-like structures: observation of a probably unknown type of senile plaque by periodic-acid methenamine silver (PAM) electron microscopy.
Acta neuropathologica 1989;78(2):137-42.
1988: Kenji Kosaka; K Tsuchiya; M Yoshimura
Lewy body disease with and without dementia: a clinicopathological study of 35 cases.
Clinical neuropathology 1988;7(6):299-305.
1988: H Shini; Y Ichimiya; Kenji Kosaka; R Iitsuka
[Changes in brain level of neurotransmitters in Alzheimer's disease].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1988;90(10):863-9.
1987: K Ikeda; Kenji Kosaka; A Hori
Intraneuronal polyglucosan bodies and peculiar inclusions in the midbrain-tegmentum of the aged.
The Japanese journal of psychiatry and neurology 1987;41(4):719-23.
1987: Kenji Kosaka; K Hama; I Nagatsu; J Y Wu; O P Ottersen; J Storm-Mathisen; T Kosaka
Postnatal development of neurons containing both catecholaminergic and GABAergic traits in the rat main olfactory bulb.
Brain research 1987;403(2):355-60.
1987: Kenji Kosaka
[Cortical dementia and subcortical dementia--comparison with Lewy body disease].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1987;89(9):661-9.
1987: K Arima; S Oyanagi; Kenji Kosaka; M Matsushita
[Distribution of Pick bodies in the central nervous system of Pick's disease with special reference to their association with neuronal loss].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1987;89(1):43-72.
1986: Kenji Kosaka; K Ikeda; M Matsushita; R Iizuka
A combination of Alzheimer's and Binswanger's diseases--a clinicopathological study of four cases.
The Japanese journal of psychiatry and neurology 1986;40(4):685-92.
1986: Heii Arai; T Moroji; Kenji Kosaka; R Iizuka
Extrahypophyseal distribution of alpha-melanocyte stimulating hormone (alpha-MSH)-like immunoreactivity in postmortem brains from normal subjects and Alzheimer-type dementia patients.
Brain research 1986;377(2):305-10.
1986: Y Ichimiya; K Kobayashi; Heii Arai; K Ikeda; Kenji Kosaka
A computed tomography study of Alzheimer's disease by regional volumetric and parenchymal density measurements.
Journal of neurology 1986;233(3):164-7.
1986: H Sasaki; O Muramoto; I Kanazawa; Heii Arai; Kenji Kosaka; R Iizuka
Regional distribution of amino acid transmitters in postmortem brains of presenile and senile dementia of Alzheimer type.
Annals of neurology 1986;19(3):263-9.
1986: Y Ichimiya; Heii Arai; Kenji Kosaka; R Iizuka
Morphological and biochemical changes in the cholinergic and monoaminergic systems in Alzheimer-type dementia.
Acta neuropathologica 1986;70(2):112-6.
1985: Heii Arai; K Kobayashi; Y Ichimiya; Kenji Kosaka; R Iizuka
Free amino acids in post-mortem cerebral cortices from patients with Alzheimer-type dementia.
Neuroscience research 1985;2(6):486-90.
1985: Kenji Kosaka; Heii Arai; K Ikeda
Familial presenile dementia with CJD-like lesions: preliminary results.
Clinical neuropathology 1985;4(4):149-55.
1984: Heii Arai; T Moroji; Kenji Kosaka
Somatostatin and vasoactive intestinal polypeptide in postmortem brains from patients with Alzheimer-type dementia.
Neuroscience letters 1984;52(1-2):73-8.
1984: Heii Arai; Kenji Kosaka; O Muramoto; R Iizuka
[A biochemical study of cholinergic neurons of the post-mortem brains from the patients with Alzheimer-type dementia].
Rinshō shinkeigaku = Clinical neurology 1984;24(11):1128-35.
1984: N Horita; Kenji Kosaka; M Matsushita
[Chronic neuropathologic change of experimental Wernicke's encephalopathy].
Rinshō shinkeigaku = Clinical neurology 1984;24(9):891-900.
1984: Kenji Kosaka; M Yoshimura; K Ikeda; Herbert Budka
Diffuse type of Lewy body disease: progressive dementia with abundant cortical Lewy bodies and senile changes of varying degree--a new disease?
Clinical neuropathology 1984;3(5):185-92.
1984: Heii Arai; Kenji Kosaka; R Iizuka
Changes of biogenic amines and their metabolites in postmortem brains from patients with Alzheimer-type dementia.
Journal of neurochemistry 1984;43(2):388-93.
1984: Y Ichimiya; K Kobayashi; Heii Arai; K Ikeda; Kenji Kosaka
[A comparative study of Alzheimer's disease and Pick's disease by CT].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1984;86(11):879-96.
1984: K Kobayashi; Heii Arai; K Ikeda; Kenji Kosaka
[A computed tomography study of Pick's disease].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1984;86(6):401-16.
1984: Heii Arai; K Kobayashi; Y Ichimiya; Kenji Kosaka; R Iizuka
A preliminary study of free amino acids in the postmortem temporal cortex from Alzheimer-type dementia patients.
Neurobiology of aging 1984;5(4):319-21.
1983: Heii Arai; K Kobayashi; K Ikeda; Y Nagao; R Ogihara; Kenji Kosaka
[CT study in Alzheimer's disease].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1983;85(1):1-14.
1983: Heii Arai; K Kobayashi; K Ikeda; Y Nagao; R Ogihara; Kenji Kosaka
A computed tomography study of Alzheimer's disease.
Journal of neurology 1983;229(2):69-77.
1982: Kenji Kosaka; M Matsushita; R Iizuka; P Mehraein
Pick's disease and head trauma.
Folia psychiatrica et neurologica japonica 1982;36(2):125-35.
1982: Kenji Kosaka; M Matsushita; P Mehraein
[A clinicopathological study of Pick's disease--our sixty autopsied cases (author's transl)].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1982;84(2):101-13.
1982: O Muramoto; S Nanko; Kenji Kosaka; K Nagao; K Ando; T Takasu
[Suspected cases of familial Alzheimer's disease-a case report and a study on aneuploidy in leukocytes (author's transl)].
Nō to shinkei = Brain and nerve 1982;34(1):71-6.
1981: Kenji Kosaka; R Iizuka; Y Mizutani; T Kondo; Toshiharu Nagatsu
Striatonigral degeneration combined with Alzheimer's disease.
Acta neuropathologica 1981;54(3):253-6.
1980: Kenji Kosaka; M Matsushita; S Oyanagi; K Hato; P Mehraein
[Pick's disease with concomitant traumatic brain damage--five autopsied cases and a critical review of literatures (author's transl)].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1980;82(1):33-47.
1980: Kenji Kosaka; M Matsushita; S Oyanagi; P Mehraein
[A cliniconeurophathological study of the "Lewy body disease"].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1980;82(5):292-311.
1979: Kenji Kosaka; P Mehraein
Dementia-Parkinsonism syndrome with numerous Lewy bodies and senile plaques in cerebral cortex.
Archiv für Psychiatrie und Nervenkrankheiten 1979;226(4):241-50.
1978: Kenji Kosaka
Lewy bodies in cerebral cortex, report of three cases.
Acta neuropathologica 1978;42(2):127-34.
1977: Kenji Kosaka; S Oyanagi; M Matsushita; A Hori; S Iwase
Multiple system degeneration and involving thalamus, reticular formation, pallido-nigral, pallido-luysian and dentato-rubral systems. A case report.
Acta neuropathologica 1977;39(1):89-95.
1976: Kenji Kosaka; S Oyanagi; M Matsushita; A Hori
Presenile dementia with Alzheimer-, Pick- and Lewy-body changes.
Acta neuropathologica 1976;36(3):221-33.
1976: Kenji Kosaka
[On the therapeutic approach to out-patients with organic dementia based on ageing processes of the brain (author's transl)].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1976;78(10-11):719-30.
1976: M Matushita; Kenji Kosaka; A Hori; S Hanawa; Y Machii
[On the combined cases with vascular dementia and senile dementia--analysis of the clincal findings of 8 cases (author's transl)].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1976;78(10-11):703-17.
1974: Kenji Kosaka; H Kobayashi; T Hoshino; H Shibayama; S Iwase
[Cinico-pathological study of three cases diagnosed as alcoholic Wernicke's disease (author's transl)].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1974;76(5):367-87.
1973: Kenji Kosaka; H Shibayama; H Kobayashi; T Hoshino; S Iwase
[An autopsy case of unclassifiable presenile dementia].
Seishin shinkeigaku zasshi = Psychiatria et neurologia Japonica 1973;75(1):18-34.