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Kenneth Kosik

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Margarita Giraldo; Julian Carvajal; Richard J Caselli; Jason J Corneveaux; Chris Gaiteri; Kenneth S Kosik; Francisco Lopera; Claudia Muñoz; Amanda Myers; Manuel Ramirez-Restrepo; Eric M Reiman; Isabelle Schrauwen; Ashley L Siniard; Matthew Huentelman
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease.
Kenneth S Kosik
Molecular biology: Circles reshape the RNA world.
Benoit J Smagghe; Andrew K Stewart; Kyle J Bernier; Amy K Calhoun; Mark G Carter; Brian A DiNardo; Eric J Hartman; Vasilios M Hatziioannou; Brian A Kirk; Kenneth S Kosik; Gabriele Lillacci; Laura M Shelton; Cynthia Bamdad
MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state.

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2013: Margarita Giraldo; Julian Carvajal; Richard J Caselli; Jason J Corneveaux; Chris Gaiteri; Kenneth S Kosik; Francisco Lopera; Claudia Muñoz; Amanda Myers; Manuel Ramirez-Restrepo; Eric M Reiman; Isabelle Schrauwen; Ashley L Siniard; Matthew Huentelman
Variants in triggering receptor expressed on myeloid cells 2 are associated with both behavioral variant frontotemporal lobar degeneration and Alzheimer's disease.
Neurobiology of aging 2013;34(8):2077.e11-8.
2013: Kenneth S Kosik
Molecular biology: Circles reshape the RNA world.
Nature 2013;495(7441):322-4.
2013: Benoit J Smagghe; Andrew K Stewart; Kyle J Bernier; Amy K Calhoun; Mark G Carter; Brian A DiNardo; Eric J Hartman; Vasilios M Hatziioannou; Brian A Kirk; Kenneth S Kosik; Gabriele Lillacci; Laura M Shelton; Cynthia Bamdad
MUC1* ligand, NM23-H1, is a novel growth factor that maintains human stem cells in a more naïve state.
PloS one 2013;8(3):e58601.
2012: Adam S Fleisher; Gloria Garcia; Margarita Giraldo; Madelyn Gutierrez Gomez; Matthew Huentelman; Laura J Jakimovich; Kenneth S Kosik; Jessica B S Langbaum; Carolyn M Langois; Wendy Lee; Francisco Lopera; Liliana Lopez; Hua Mo; Sonia Moreno; Yakeel T Quiroz; Rebecca A Reiman; Auttawut Roontiva; Pierre N. Tariot; Pradeep Thiyyagura; Natalia Acosta-Baena; Napatkamon Ayutyanont; Kewei Chen; Eric M Reiman
Florbetapir PET analysis of amyloid-β deposition in the presenilin 1 E280A autosomal dominant Alzheimer's disease kindred: a cross-sectional study.
Lancet neurology 2012;11(12):1057-65.
2012: Eric M Reiman; Rebecca A Reiman; Aarti R Shah; Reisa A Sperling; Chantal E Stern; Pierre N. Tariot; Victoria Tirado; Carlos Velez-Pardo; Natalia Acosta-Baena; Gene E Alexander; Sergio Alvarez; Andrés Arbelaez; Kewei Chen; Brad Dickerson; Anne M Fagan; Adam S Fleisher; Margarita Giraldo; Matthew Huentelman; Marlene Jimenez del Rio; Kenneth S Kosik; Jessica B S Langbaum; Claudia Munoz; Yakeel T Quiroz; Francisco Lopera
Brain imaging and fluid biomarker analysis in young adults at genetic risk for autosomal dominant Alzheimer's disease in the presenilin 1 E280A kindred: a case-control study.
Lancet neurology 2012;11(12):1048-56.
2012: Matthew A Lalli; L Madrigal; Mary Luz Arcila; Mauricio Arcos-Burgos; Gloria Garcia; Kenneth S Kosik; Francisco Lopera
Exploratory data from complete genomes of familial alzheimer disease age-at-onset outliers.
Human mutation 2012;33(12):1630-4.
2012: Hongjun Zhou; Mary Luz Arcila; Christine Henzler; Eun Joo Lee; Zhonghan Li; Jingya Liu; Tariq M Rana; Kenneth S Kosik
Deep annotation of mouse iso-miR and iso-moR variation.
Nucleic acids research 2012;40(13):5864-75.
2012: Cecilia Conaco; Bernard M Degnan; Sandie M Degnan; Mary Luz Arcila; Danielle S Bassett; Hongjun Zhou; Kenneth S Kosik
Functionalization of a protosynaptic gene expression network.
Proceedings of the National Academy of Sciences of the United States of America 2012;109 Suppl 1():10612-8.
2012: Kenneth S Kosik; Peter R Rapp; Naftali Raz; Scott A Small; J David Sweatt; Li-Huei Tsai
Mechanisms of age-related cognitive change and targets for intervention: epigenetics.
The journals of gerontology. Series A, Biological sciences and medical sciences 2012;67(7):741-6.
2012: Thales Papagiannakopoulos; David H Rowitch; Inder M Verma; H Zong; B A Barres; J C Dugas; Dinorah Friedmann-Morvinski; R M Gill; Emmanuelle Huillard; C Liu; P Neveu; Kenneth S Kosik
Pro-neural miR-128 is a glioma tumor suppressor that targets mitogenic kinases.
Oncogene 2012;31(15):1884-95.
2012: Cecilia Conaco; Bernard M Degnan; Sandie M Degnan; Pierre Neveu; Hongjun Zhou; Mary Luz Arcila; Kenneth S Kosik
Transcriptome profiling of the demosponge Amphimedon queenslandica reveals genome-wide events that accompany major life cycle transitions.
BMC genomics 2012;13():209.
2011: Eun Joo Lee; Sourav Banerjee; Hongjun Zhou; Aruna Jammalamadaka; Mary Arcila; B S Manjunath; Kenneth S Kosik
Identification of piRNAs in the central nervous system.
RNA (New York, N.Y.) 2011;17(6):1090-9.
2011: Kenneth S Kosik
PhDs: what's left if science abdicates?
Nature 2011;473(7347):284.
2011: Joydev K Laha; Xuemei Zhang; Lixin Qiao; Min Liu; Snigdha Chatterjee; Shaughnessy Robinson; Kenneth S Kosik; Gregory D Cuny
Structure-activity relationship study of 2,4-diaminothiazoles as Cdk5/p25 kinase inhibitors.
Bioorganic & medicinal chemistry letters 2011;21(7):2098-101.
2011: Eric Reiman; Napatkamon Ayutyanont; Richard Caselli; Kewei Chen; Adam S Fleisher; Kenneth S Kosik; Jessica B S Langbaum; Francisco Lopera; Yakeel T Quiroz; Pierre N. Tariot
Alzheimer's Prevention Initiative: a plan to accelerate the evaluation of presymptomatic treatments.
Journal of Alzheimer's disease : JAD 2011;26 Suppl 3():321-9.
2011: Min-Jeong Kye; Yong-Seok Lee; Pierre Neveu; Mustafa Sahin; Judith A Steen; Miou Zhou; Kenneth S Kosik; Alcino J Silva
NMDA mediated contextual conditioning changes miRNA expression.
PloS one 2011;6(9):e24682.
2010: Pierre Neveu; Min Jeong Kye; Shuping Qi; David E Buchholz; Dennis O Clegg; Mustafa Sahin; In-Hyun Park; Kwang-Soo Kim; George Q Daley; Harley I Kornblum; Boris I Shraiman; Kenneth S Kosik
MicroRNA profiling reveals two distinct p53-related human pluripotent stem cell states.
Cell stem cell 2010;7(6):671-81.
2010: Yanhong Shi; Xinyu Zhao; Jenny Hsieh; Hynek Wichterle; Soren Impey; Sourav Banerjee; Pierre Neveu; Kenneth S Kosik
MicroRNA regulation of neural stem cells and neurogenesis.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(45):14931-6.
2010: Diego Piedrahita; Israel Hernández; Alejandro López-Tobón; Dmitry Fedorov; Boguslaw Obara; Bs Manjunath; Ryan L Boudreau; Beverly Davidson; Frank Laferla; Juan Carlos Gallego-Gómez; Kenneth S Kosik; Gloria Patricia Cardona-Gómez
Silencing of CDK5 reduces neurofibrillary tangles in transgenic alzheimer's mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2010;30(42):13966-76.
2010: Kenneth S Kosik
MicroRNAs and cellular phenotypy.
Cell 2010;143(1):21-6.
2010: Theresa M Yuraszeck; Pierre Neveu; Maria Rodriguez-Fernandez; Anne Robinson; Kenneth S Kosik; Francis J Doyle
Vulnerabilities in the tau network and the role of ultrasensitive points in tau pathophysiology.
PLoS computational biology 2010;6(11):e1000997.
2009: Sourav Banerjee; Pierre Neveu; Kenneth S Kosik
A coordinated local translational control point at the synapse involving relief from silencing and MOV10 degradation.
Neuron 2009;64(6):871-84.
2009: Sarah K Fineberg; Kenneth S Kosik; Beverly L Davidson
MicroRNAs potentiate neural development.
Neuron 2009;64(3):303-9.
2009: Kenneth S Kosik
MicroRNAs tell an evo-devo story.
Nature reviews. Neuroscience 2009;10(10):754-9.
2009: Kumi Sasaki; Hideki Shimura; Masako Itaya; Ryota Tanaka; Hideo Mori; Yoshikuni Mizuno; Kenneth S Kosik; Shigeki Tanaka; Nobutaka Hattori
Excitatory amino acid transporter 2 associates with phosphorylated tau and is localized in neurofibrillary tangles of tauopathic brains.
FEBS letters 2009;583(13):2194-200.
2009: Na Xu; Thales Papagiannakopoulos; Guangjin Pan; James A Thomson; Kenneth S Kosik
MicroRNA-145 regulates OCT4, SOX2, and KLF4 and represses pluripotency in human embryonic stem cells.
Cell 2009;137(4):647-58.
2009: Thales Papagiannakopoulos; Kenneth S Kosik
MicroRNA-124: micromanager of neurogenesis.
Cell stem cell 2009;4(5):375-6.
2009: Kenneth S Kosik
Exploring the early origins of the synapse by comparative genomics.
Biology letters 2009;5(1):108-11.
2009: Daniel C Carrettiero; Israel Hernandez; Pierre Neveu; Thales Papagiannakopoulos; Kenneth S Kosik
The cochaperone BAG2 sweeps paired helical filament- insoluble tau from the microtubule.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(7):2151-61.
2008: Tomoyo Ochiishi; Kensuke Futai; Kenichi Okamoto; Kimihiko Kameyama; Kenneth S Kosik
Regulation of AMPA receptor trafficking by delta-catenin.
Molecular and cellular neurosciences 2008;39(4):499-507.
2008: Kawther Abu-Elneel; Tomoyo Ochiishi; Miguel Medina; Monica Remedi; Laura Gastaldi; Alfredo Caceres; Kenneth S Kosik
A delta-catenin signaling pathway leading to dendritic protrusions.
The Journal of biological chemistry 2008;283(47):32781-91.
2008: Tim R Mercer; Marcel Dinger; Jean Mariani; Kenneth S Kosik; Mark F Mehler; John S Mattick
Noncoding RNAs in Long-Term Memory Formation.
The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry 2008;14(5):434-45.
2008: Thales Papagiannakopoulos; Alice Shapiro; Kenneth S Kosik
MicroRNA-21 targets a network of key tumor-suppressive pathways in glioblastoma cells.
Cancer research 2008;68(19):8164-72.
2008: Kenneth S Kosik; Francisco Lopera
Genetic testing must recognize impact of bad news on recipient.
Nature 2008;454(7201):158-9.
2008: Kawther Abu-Elneel; Tsunglin Liu; Francesca S Gazzaniga; Yuhei Nishimura; Dennis P Wall; Daniel Geschwind; kaiqin lao; Kenneth S Kosik
Heterogeneous dysregulation of microRNAs across the autism spectrum.
Neurogenetics 2008;9(3):153-61.
2008: Onur Sakarya; Kenneth S Kosik; Todd H Oakley
Reconstructing ancestral genome content based on symmetrical best alignments and Dollo parsimony.
Bioinformatics (Oxford, England) 2008;24(5):606-12.
2008: Sherry T Hikita; Kenneth S Kosik; Dennis O Clegg; Cynthia Bamdad
MUC1* mediates the growth of human pluripotent stem cells.
PloS one 2008;3(10):e3312.
2008: Thales Papagiannakopoulos; Kenneth S Kosik
MicroRNAs: regulators of oncogenesis and stemness.
BMC medicine 2008;6():15.
2007: Marcie A Glicksman; Gregory D Cuny; Min Liu; Brittany Dobson; Kenneth Auerbach; Ross L Stein; Kenneth S Kosik
New approaches to the discovery of cdk5 inhibitors.
Current Alzheimer research 2007;4(5):547-9.
2007: Min-Jeong Kye; Tsunglin Liu; Sasha Levy; Nan Lan Xu; Benjamin B Groves; Richard Bonneau; kaiqin lao; Kenneth S Kosik
Somatodendritic microRNAs identified by laser capture and multiplex RT-PCR.
RNA (New York, N.Y.) 2007;13(8):1224-34.
2007: Tsunglin Liu; Thales Papagiannakopoulos; Kathy Puskar; Shuping Qi; Fernando Santiago; William Clay; kaiqin lao; Yohan Lee; Stanley F Nelson; Harley I Kornblum; Francis J Doyle; Linda Petzold; Boris I Shraiman; Kenneth S Kosik
Detection of a microRNA signal in an in vivo expression set of mRNAs.
PloS one 2007;2(8):e804.
2007: Onur Sakarya; Kathryn A Armstrong; Maja Adamska; Marcin Adamski; I-Fan Wang; Bruce Tidor; Bernard M Degnan; Todd H Oakley; Kenneth S Kosik
A post-synaptic scaffold at the origin of the animal kingdom.
PloS one 2007;2(6):e506.
2006: Kenneth S Kosik
The neuronal microRNA system.
Nature reviews. Neuroscience 2006;7(12):911-20.
2006: Christine P Donahue; Christina Muratore; Jane Y Wu; Kenneth S Kosik; Michael S Wolfe
Stabilization of the tau exon 10 stem loop alters pre-mRNA splicing.
The Journal of biological chemistry 2006;281(33):23302-6.
2006: Christine P Donahue; Kenneth S Kosik; Tracey J Shors
Growth hormone is produced within the hippocampus where it responds to age, sex, and stress.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(15):6031-6.
2006: Anna M Krichevsky; Kai-Christian Sonntag; Ole Isacson; Kenneth S Kosik
Specific microRNAs modulate embryonic stem cell-derived neurogenesis.
Stem cells (Dayton, Ohio) 2006;24(4):857-64.
2006: Kenneth S Kosik
Neuroscience gears up for duel on the issue of brain versus deity.
Nature 2006;439(7073):138.
2006: Kenneth S Kosik
Traveling the tau pathway: a personal account.
Journal of Alzheimer's disease : JAD 2006;9(3 Suppl):251-6.
2005: Raajit Rampal; Joseph F Arboleda-Velasquez; Aleksandra Nita-Lazar; Kenneth S Kosik; Robert S Haltiwanger
Highly conserved O-fucose sites have distinct effects on Notch1 function.
The Journal of biological chemistry 2005;280(37):32133-40.
2005: Kenneth S Kosik; Anna M Krichevsky
The Elegance of the MicroRNAs: A Neuronal Perspective.
Neuron 2005;47(6):779-82.
2005: Kenneth S Kosik; Anna M Krichevsky
Teaching resources. A model for local regulation of translation near active synapses.
Science's STKE : signal transduction knowledge environment 2005;2005(300):tr25.
2005: Jennifer A Chan; Anna M Krichevsky; Kenneth S Kosik
MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells.
Cancer research 2005;65(14):6029-33.
2005: Jae Suk Ahn; Mala L Radhakrishnan; Marina Mapelli; Sungwoon Choi; Bruce Tidor; Gregory D Cuny; Andrea Musacchio; Li-An Yeh; Kenneth S Kosik
Defining Cdk5 ligand chemical space with small molecule inhibitors of tau phosphorylation.
Chemistry & biology 2005;12(7):811-23.
2005: Joseph F Arboleda-Velasquez; Raajit Rampal; Erik Fung; Diane C Darland; Min Liu; Maria C Martinez; Christine P Donahue; Manuel F Navarro-Gonzalez; Peter Libby; Patricia A D'Amore; Masanori Aikawa; Robert S Haltiwanger; Kenneth S Kosik
CADASIL mutations impair Notch3 glycosylation by Fringe.
Human molecular genetics 2005;14(12):1631-9.
2005: Kenneth S Kosik; Christine P Donahue; Inbal Israely; Xin Liu; Tomoyo Ochiishi
Delta-catenin at the synaptic-adherens junction.
Trends in cell biology 2005;15(3):172-8.
2005: Kenneth S Kosik; Hideki Shimura
Phosphorylated tau and the neurodegenerative foldopathies.
Biochimica et biophysica acta 2005;1739(2-3):298-310.
2005: Silvia Monticelli; K Mark Ansel; Changchun Xiao; Nicholas D Socci; Anna M Krichevsky; To-Ha Thai; Nikolaus Rajewsky; Debora S Marks; Chris Sander; Klaus Rajewsky; Anjana Rao; Kenneth S Kosik
MicroRNA profiling of the murine hematopoietic system.
Genome biology 2005;6(8):R71.
2004: Deguang Zhu; Kenneth S Kosik; Thomas E Meigs; Vijay Yanamadala; Bradley M Denker
Galpha12 directly interacts with PP2A: evidence FOR Galpha12-stimulated PP2A phosphatase activity and dephosphorylation of microtubule-associated protein, tau.
The Journal of biological chemistry 2004;279(53):54983-6.
2004: Min Liu; Jake Ni; Kenneth S Kosik; Li-An Yeh
Development of a fluorescent high throughput assay for tau aggregation.
Assay and drug development technologies 2004;2(6):609-19.
2004: Alejandra R Alvarez; Pablo C Sandoval; Nancy R Leal; Paula U Castro; Kenneth S Kosik
Activation of the neuronal c-Abl tyrosine kinase by amyloid-beta-peptide and reactive oxygen species.
Neurobiology of disease 2004;17(2):326-36.
2004: Inbal Israely; Rui M Costa; Cui Wei Xie; Alcino J Silva; Kenneth S Kosik; Xin Liu
Deletion of the neuron-specific protein delta-catenin leads to severe cognitive and synaptic dysfunction.
Current biology : CB 2004;14(18):1657-63.
2004: Peter J Morin; Miguel Medina; Mikhail Semenov; Anthony M C Brown; Kenneth S Kosik
Wnt-1 expression in PC12 cells induces exon 15 deletion and expression of L-APP.
Neurobiology of disease 2004;16(1):59-67.
2004: Hideki Shimura; Yuko Miura-Shimura; Kenneth S Kosik
Binding of tau to heat shock protein 27 leads to decreased concentration of hyperphosphorylated tau and enhanced cell survival.
The Journal of biological chemistry 2004;279(17):17957-62.
2004: Jae Suk Ahn; Andrea Musacchio; Marina Mapelli; Jake Ni; Leonard Scinto; Ross Stein; Kenneth S Kosik; Li-An Yeh
Development of an assay to screen for inhibitors of tau phosphorylation by cdk5.
Journal of biomolecular screening 2004;9(2):122-31.
2004: Hideki Shimura; Daniel Schwartz; Steven P Gygi; Kenneth S Kosik
CHIP-Hsc70 complex ubiquitinates phosphorylated tau and enhances cell survival.
The Journal of biological chemistry 2004;279(6):4869-76.
2004: Shih-Chu Kao; Anna M Krichevsky; Kenneth S Kosik; Li-Huei Tsai
BACE1 suppression by RNA interference in primary cortical neurons.
The Journal of biological chemistry 2004;279(3):1942-9.
2004: John Kim; Anna M Krichevsky; Yonatan Grad; Gabriel D Hayes; Kenneth S Kosik; George M Church; Gary Ruvkun
Identification of many microRNAs that copurify with polyribosomes in mammalian neurons.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(1):360-5.
2004: Michaela Monshausen; Niels H Gehring; Kenneth S Kosik
The mammalian RNA-binding protein Staufen2 links nuclear and cytoplasmic RNA processing pathways in neurons.
Neuromolecular medicine 2004;6(2-3):127-44.
2004: Nelson Ruiz-Opazo; Kenneth S Kosik; Lyle V Lopez; Pia Bagamasbad; Lorenz R B Ponce; Victoria L M Herrera
Attenuated hippocampus-dependent learning and memory decline in transgenic TgAPPswe Fischer-344 rats.
Molecular medicine (Cambridge, Mass.) 2004;10(1-6):36-44.
2004: Christine P Donahue; Kenneth S Kosik
Distribution pattern of Notch3 mutations suggests a gain-of-function mechanism for CADASIL.
Genomics 2004;83(1):59-65.
2003: Anna M Krichevsky; Kevin S King; Christine P Donahue; Konstantin Khrapko; Kenneth S Kosik
A microRNA array reveals extensive regulation of microRNAs during brain development.
RNA (New York, N.Y.) 2003;9(10):1274-81.
2003: Pau Pastor; Catherine M Roe; Andrés Villegas; Gabriel Bedoya; Sumi Chakraverty; Gloria García; Victoria Tirado; Joanne Norton; Silvia Ríos; Maribel Martínez; Kenneth S Kosik; Francisco Lopera; Alison Goate
Apolipoprotein Eepsilon4 modifies Alzheimer's disease onset in an E280A PS1 kindred.
Annals of neurology 2003;54(2):163-9.
2003: Maria Cruz Martinez; Tomoyo Ochiishi; Michael Majewski; Kenneth S Kosik
Dual regulation of neuronal morphogenesis by a delta-catenin-cortactin complex and Rho.
The Journal of cell biology 2003;162(1):99-111.
2003: Kenneth S Kosik
Beyond phrenology, at last.
Nature reviews. Neuroscience 2003;4(3):234-9.
2002: Kenneth S Kosik; Jae Ahn; Ross Stein; Li-An Yeh
Discovery of compounds that will prevent tau pathology.
Journal of molecular neuroscience : MN 2002;19(3):261-6.
2002: Kelsey C Martin; Kenneth S Kosik
Synaptic tagging -- who's it?
Nature reviews. Neuroscience 2002;3(10):813-20.
2002: Anna M Krichevsky; Kenneth S Kosik
RNAi functions in cultured mammalian neurons.
Proceedings of the National Academy of Sciences of the United States of America 2002;99(18):11926-9.
2002: Meredith D Temple; Kenneth S Kosik; Oswald Steward
Spatial learning and memory is preserved in rats after early development in a microgravity environment.
Neurobiology of learning and memory 2002;78(2):199-216.
2002: Joseph F Arboleda-Velasquez; Francisco Lopera; E Lopez; M P Frosch; D Sepulveda-Falla; J E Gutierrez; S Vargas; Miguel Medina; C Martinez De Arrieta; R V Lebo; S A Slaugenhaupt; Rebecca A Betensky; A Villegas; Mauricio Arcos-Burgos; Dora Rivera; J C Restrepo; Kenneth S Kosik
C455R notch3 mutation in a Colombian CADASIL kindred with early onset of stroke.
Neurology 2002;59(2):277-9.
2002: Michael G Schlossmacher; Matthew P Frosch; Wei Ping Gai; Miguel Medina; Nutan Sharma; Lysia Forno; Tomoyo Ochiishi; Hideki Shimura; Ronit Sharon; Nobutaka Hattori; J William Langston; Yoshikuni Mizuno; Bradley T Hyman; Dennis J Selkoe; Kenneth S Kosik
Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies.
The American journal of pathology 2002;160(5):1655-67.
2002: Richard P Laura; Andrea S Witt; Heike A Held; Resi Gerstner; Kurt Deshayes; Michael F T Koehler; Kenneth S Kosik; Sachdev S Sidhu; Laurence A Lasky
The Erbin PDZ domain binds with high affinity and specificity to the carboxyl termini of delta-catenin and ARVCF.
The Journal of biological chemistry 2002;277(15):12906-14.
2002: Kenneth S Kosik; Anna M Krichevsky
The message and the messenger: delivering RNA in neurons.
Science's STKE : signal transduction knowledge environment 2002;2002(126):pe16.
2002: Q Lu; Nishit K Mukhopadhyay; James D Griffin; M Paredes; Miguel Medina; Kenneth S Kosik
Brain armadillo protein delta-catenin interacts with Abl tyrosine kinase and modulates cellular morphogenesis in response to growth factors.
Journal of neuroscience research 2002;67(5):618-24.
2002: Christine P Donahue; Roderick V Jensen; Tomoyo Ochiishi; Ingrid Eisenstein; Mingrui Zhao; Tracey J Shors; Kenneth S Kosik
Transcriptional profiling reveals regulated genes in the hippocampus during memory formation.
Hippocampus 2002;12(6):821-33.
2001: Anna M Krichevsky; Kenneth S Kosik
Neuronal RNA granules: a link between RNA localization and stimulation-dependent translation.
Neuron 2001;32(4):683-96.
2001: Peter J Neumann; Sally S Araki; A Arcelus; A Longo; George Papadopoulos; Kenneth S Kosik; Karen M Kuntz; Ashoke Bhattacharjya
Measuring Alzheimer's disease progression with transition probabilities: estimates from CERAD.
Neurology 2001;57(6):957-64.
2001: Peter J Neumann; James K Hammitt; C Mueller; H M Fillit; J Hill; N A Tetteh; Kenneth S Kosik
Public attitudes about genetic testing for Alzheimer's disease.
Health affairs (Project Hope) 2001;20(5):252-64.
2001: Hideki Shimura; Michael G Schlossmacher; Nobutaka Hattori; Matthew P Frosch; A Trockenbacher; R Schneider; Yoshikuni Mizuno; Kenneth S Kosik; Dennis J Selkoe
Ubiquitination of a new form of alpha-synuclein by parkin from human brain: implications for Parkinson's disease.
Science (New York, N.Y.) 2001;293(5528):263-9.
2001: Keith A Johnson; Francisco Lopera; K Jones; A Becker; Reisa Sperling; J Hilson; J Londono; I Siegert; M Arcos; S Moreno; L Madrigal; Jorge E Ossa; N Pineda; Alfredo Ardila; M Roselli; Marilyn S Albert; Kenneth S Kosik; A Rios
Presenilin-1-associated abnormalities in regional cerebral perfusion.
Neurology 2001;56(11):1545-51.
2001: P Kunda; Gabriela Paglini; Santiago Quiroga; Kenneth S Kosik; A Caceres
Evidence for the involvement of Tiam1 in axon formation.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(7):2361-72.
2001: Kenneth S Kosik
The high flying genome.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(2):203-5.
2001: M Lu; Kenneth S Kosik
Competition for microtubule-binding with dual expression of tau missense and splice isoforms.
Molecular biology of the cell 2001;12(1):171-84.
2000: Elizabeth Noll; Miguel Medina; D Hartley; J Zhou; Norbert Perrimon; Kenneth S Kosik
Presenilin affects arm/beta-catenin localization and function in Drosophila.
Developmental biology 2000;227(2):450-64.
2000: M S Rook; M Lu; Kenneth S Kosik
CaMKIIalpha 3' untranslated region-directed mRNA translocation in living neurons: visualization by GFP linkage.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(17):6385-93.
2000: Alfredo Ardila; Francisco Lopera; Mónica Rosselli; Sonia Moreno; L Madrigal; Juan Carlos Arango Lasprilla; M Arcos; C Murcia; JC Arango-Viana; Jorge E Ossa; Alison Goate; Kenneth S Kosik
Neuropsychological profile of a large kindred with familial Alzheimer's disease caused by the E280A single presenilin-1 mutation.
Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists 2000;15(6):515-28.
2000: Mónica Rosselli; Alfredo Ardila; S C Moreno; V C Standish; Juan Carlos Arango Lasprilla; Victoria Tirado; J M Ossa; Alison Goate; Kenneth S Kosik; Francisco Lopera
Cognitive decline in patients with familial Alzheimer's disease associated with E280a presenilin-1 mutation: a longitudinal study.
Journal of clinical and experimental neuropsychology 2000;22(4):483-95.
2000: C Ho; J Zhou; Miguel Medina; T Goto; M Jacobson; P G Bhide; Kenneth S Kosik
delta-catenin is a nervous system-specific adherens junction protein which undergoes dynamic relocalization during development.
The Journal of comparative neurology 2000;420(2):261-76.
2000: Miguel Medina; RC Marinescu; J Overhauser; Kenneth S Kosik
Hemizygosity of delta-catenin (CTNND2) is associated with severe mental retardation in cri-du-chat syndrome.
Genomics 2000;63(2):157-64.
2000: Kenneth S Kosik
The long reach of evolution and development. Effects on the Alzheimer brain.
Annals of the New York Academy of Sciences 2000;924():76-80.
2000: Peter T Lansbury; Kenneth S Kosik
Neurodegeneration: new clues on inclusions.
Chemistry & biology 2000;7(1):R9-R12.
1999: T Gómez-Isla; Whitfield B Growdon; MJ McNamara; David Nochlin; Thomas D Bird; JC Arango; Francisco Lopera; Kenneth S Kosik; P L Lantos; Nigel J Cairns; Bradley T Hyman
The impact of different presenilin 1 andpresenilin 2 mutations on amyloid deposition, neurofibrillary changes and neuronal loss in the familial Alzheimer's disease brain: evidence for other phenotype-modifying factors.
Brain : a journal of neurology 1999;122 ( Pt 9)():1709-19.
1999: Kenneth S Kosik
A notable cleavage: winding up with beta-amyloid.
Proceedings of the National Academy of Sciences of the United States of America 1999;96(6):2574-6.
1999: Q Lu; M Paredes; Miguel Medina; J Zhou; R Cavallo; Mark Peifer; L Orecchio; Kenneth S Kosik
delta-catenin, an adhesive junction-associated protein which promotes cell scattering.
The Journal of cell biology 1999;144(3):519-32.
1999: Kenneth S Kosik
A partnership that delivers.
Nature medicine 1999;5(2):149-50.
1998: Gabriela Paglini; P Kunda; Santiago Quiroga; Kenneth S Kosik; Alfredo Cáceres
Suppression of radixin and moesin alters growth cone morphology, motility, and process formation in primary cultured neurons.
The Journal of cell biology 1998;143(2):443-55.
1998: S J Lee; U Liyanage; P E Bickel; Weiming Xia; Peter T Lansbury; Kenneth S Kosik
A detergent-insoluble membrane compartment contains A beta in vivo.
Nature medicine 1998;4(6):730-4.
1998: Q Lu; M Paredes; J Zhang; Kenneth S Kosik
Basal extracellular signal-regulated kinase activity modulates cell-cell and cell-matrix interactions.
Molecular and cellular biology 1998;18(6):3257-65.
1998: Kenneth S Kosik
Presenilin interactions and Alzheimer's disease.
Science (New York, N.Y.) 1998;279(5350):463-5.
1998: Kenneth S Kosik
Neurolab: learning how the nervous system adapts to microgravity.
Neuroscience news 1998;1(5):36-8.
1998: Adriana Ferreira; L S Chin; L Li; Lorene Lanier; Kenneth S Kosik; Paul Greengard
Distinct roles of synapsin I and synapsin II during neuronal development.
Molecular medicine (Cambridge, Mass.) 1998;4(1):22-8.
1998: Gary J. Bassell; Honglai Zhang; A L Byrd; Andrea M Femino; Robert H Singer; K L Taneja; Lawrence Lifshitz; I M Herman; Kenneth S Kosik
Sorting of beta-actin mRNA and protein to neurites and growth cones in culture.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1998;18(1):251-65.
1997: R B Knowles; Kenneth S Kosik
Neurotrophin-3 signals redistribute RNA in neurons.
Proceedings of the National Academy of Sciences of the United States of America 1997;94(26):14804-8.
1997: G F Hall; J Yao; M E Selzer; Kenneth S Kosik
Cytoskeletal changes correlated with the loss of neuronal polarity in axotomized lamprey central neurons.
Journal of neurocytology 1997;26(11):733-53.
1997: M Lu; W Witke; D J Kwiatkowski; Kenneth S Kosik
Delayed retraction of filopodia in gelsolin null mice.
The Journal of cell biology 1997;138(6):1279-87.
1997: LA Flanagan; C C Cunningham; J Chen; G D Prestwich; Kenneth S Kosik; Paul A Janmey
The structure of divalent cation-induced aggregates of PIP2 and their alteration by gelsolin and tau.
Biophysical journal 1997;73(3):1440-7.
1997: Gerardo Morfini; Santiago Quiroga; A Rosa; Kenneth S Kosik; Alfredo Cáceres
Suppression of KIF2 in PC12 cells alters the distribution of a growth cone nonsynaptic membrane receptor and inhibits neurite extension.
The Journal of cell biology 1997;138(3):657-69.
1997: J Zhou; U Liyanage; Miguel Medina; C Ho; AD Simmons; M Lovett; Kenneth S Kosik
Presenilin 1 interaction in the brain with a novel member of the Armadillo family.
Neuroreport 1997;8(8):2085-90.
1997: J Zhou; U Liyanage; Miguel Medina; C Ho; AD Simmons; M Lovett; Kenneth S Kosik
Presenilin 1 interaction in the brain with a novel member of the Armadillo family.
Neuroreport 1997;8(6):1489-94.
1997: Francisco Lopera; A Ardilla; A Martínez; L Madrigal; JC Arango-Viana; Cynthia A Lemere; Juan Carlos Arango Lasprilla; L Hincapíe; Mauricio Arcos-Burgos; Jorge E Ossa; I M Behrens; Joanne Norton; Corinne Lendon; Alison Goate; Andres Ruiz-Linares; Mónica Rosselli; Kenneth S Kosik
Clinical features of early-onset Alzheimer disease in a large kindred with an E280A presenilin-1 mutation.
JAMA : the journal of the American Medical Association 1997;277(10):793-9.
1997: C C Cunningham; N Leclerc; LA Flanagan; M Lu; Paul A Janmey; Kenneth S Kosik
Microtubule-associated protein 2c reorganizes both microtubules and microfilaments into distinct cytological structures in an actin-binding protein-280-deficient melanoma cell line.
The Journal of cell biology 1997;136(4):845-57.
1997: Corinne Lendon; A Martinez; I M Behrens; Kenneth S Kosik; L Madrigal; Joanne Norton; Rosalind J Neuman; Amanda Myers; F Busfield; MA Wragg; M Arcos; JC Arango-Viana; Jorge E Ossa; A Ruiz; Alison Goate; Francisco Lopera
E280A PS-1 mutation causes Alzheimer's disease but age of onset is not modified by ApoE alleles.
Human mutation 1997;10(3):186-95.
1997: Adriana Ferreira; Q Lu; L Orecchio; Kenneth S Kosik
Selective phosphorylation of adult tau isoforms in mature hippocampal neurons exposed to fibrillar A beta.
Molecular and cellular neurosciences 1997;9(3):220-34.
1996: R B Knowles; J H Sabry; Maryann E Martone; Thomas J Deerinck; M H Ellisman; Gary J. Bassell; Kenneth S Kosik
Translocation of RNA granules in living neurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1996;16(24):7812-20.
1996: Cynthia A Lemere; Francisco Lopera; Kenneth S Kosik; Corinne Lendon; Jorge E Ossa; Takaomi C Saido; Haruyasu Yamaguchi; A Ruiz; A Martinez; L Madrigal; L Hincapie; JC Arango; D C Anthony; Edward H Koo; Alison Goate; Dennis J Selkoe; J C Arango
The E280A presenilin 1 Alzheimer mutation produces increased A beta 42 deposition and severe cerebellar pathology.
Nature medicine 1996;2(10):1146-50.
1996: M Morishima-Kawashima; Kenneth S Kosik
The pool of map kinase associated with microtubules is small but constitutively active.
Molecular biology of the cell 1996;7(6):893-905.
1996: Adriana Ferreira; Kenneth S Kosik
Accelerated neuronal differentiation induced by p53 suppression.
Journal of cell science 1996;109 ( Pt 6)():1509-16.
1996: A Andreadis; B K Wagner; J A Broderick; Kenneth S Kosik
A tau promoter region without neuronal specificity.
Journal of neurochemistry 1996;66(6):2257-63.
1996: Nicole Leclerc; Peter W Baas; C C Garner; Kenneth S Kosik
Juvenile and mature MAP2 isoforms induce distinct patterns of process outgrowth.
Molecular biology of the cell 1996;7(3):443-55.
1996: M C DiTella; F Feiguin; N Carri; Kenneth S Kosik; Alfredo Cáceres
MAP-1B/TAU functional redundancy during laminin-enhanced axonal growth.
Journal of cell science 1996;109 ( Pt 2)():467-77.
1996: Kenneth S Kosik; W Q Qiu; Steven A Greenberg
Cellular signaling pathways and cytoskeletal organization.
Annals of the New York Academy of Sciences 1996;777():114-20.
1996: Adriana Ferreira; L Li; L S Chin; Paul Greengard; Kenneth S Kosik
Postsynaptic element contributes to the delay in synaptogenesis in synapsin I-deficient neurons.
Molecular and cellular neurosciences 1996;8(4):286-99.
1995: M Mercken; I Fischer; Kenneth S Kosik; Ralph A. Nixon
Three distinct axonal transport rates for tau, tubulin, and other microtubule-associated proteins: evidence for dynamic interactions of tau with microtubules in vivo.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1995;15(12):8259-67.
1995: L S Chin; L Li; Adriana Ferreira; Kenneth S Kosik; Paul Greengard
Impairment of axonal development and of synaptogenesis in hippocampal neurons of synapsin I-deficient mice.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9230-4.
1995: Adriana Ferreira; H Q Han; Paul Greengard; Kenneth S Kosik
Suppression of synapsin II inhibits the formation and maintenance of synapses in hippocampal culture.
Proceedings of the National Academy of Sciences of the United States of America 1995;92(20):9225-9.
1995: Steven M Greenberg; Wei Qiao Qiu; Dennis J Selkoe; A Ben-Itzhak; Kenneth S Kosik
Amino-terminal region of the beta-amyloid precursor protein activates mitogen-activated protein kinase.
Neuroscience letters 1995;198(1):52-6.
1995: A Andreadis; J A Broderick; Kenneth S Kosik
Relative exon affinities and suboptimal splice site signals lead to non-equivalence of two cassette exons.
Nucleic acids research 1995;23(17):3585-93.
1995: Steven M Greenberg; Kenneth S Kosik
Secreted beta-APP stimulates MAP kinase and phosphorylation of tau in neurons.
Neurobiology of aging 1995;16(3):403-7; discussion 407-8.
1995: A Amaratunga; Susan E Leeman; Kenneth S Kosik; Richard E Fine
Inhibition of kinesin synthesis in vivo inhibits the rapid transport of representative proteins for three transport vesicle classes into the axon.
Journal of neurochemistry 1995;64(5):2374-6.
1994: Kenneth S Kosik
The Alzheimer's disease sphinx: a riddle with plaques and tangles.
The Journal of cell biology 1994;127(6 Pt 1):1501-4.
1994: F Feiguin; Adriana Ferreira; Kenneth S Kosik; A Caceres
Kinesin-mediated organelle translocation revealed by specific cellular manipulations.
The Journal of cell biology 1994;127(4):1021-39.
1994: Steven M Greenberg; Edward H Koo; Dennis J Selkoe; Wei Qiao Qiu; Kenneth S Kosik
Secreted beta-amyloid precursor protein stimulates mitogen-activated protein kinase and enhances tau phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 1994;91(15):7104-8.
1994: Adriana Ferreira; Kenneth S Kosik; Paul Greengard; H Q Han
Aberrant neurites and synaptic vesicle protein deficiency in synapsin II-depleted neurons.
Science (New York, N.Y.) 1994;264(5161):977-9.
1994: Gary J. Bassell; Robert H Singer; Kenneth S Kosik
Association of poly(A) mRNA with microtubules in cultured neurons.
Neuron 1994;12(3):571-82.
1994: Peter W Baas; T P Pienkowski; K A Cimbalnik; K Toyama; S Bakalis; Fridoon J Ahmad; Kenneth S Kosik
Tau confers drug stability but not cold stability to microtubules in living cells.
Journal of cell science 1994;107 ( Pt 1)():135-43.
1994: R Knowles; N LeClerc; Kenneth S Kosik
Organization of actin and microtubules during process formation in tau-expressing Sf9 cells.
Cell motility and the cytoskeleton 1994;28(3):256-64.
1994: Kenneth S Kosik; L McConlogue
Microtubule-associated protein function: lessons from expression in Spodoptera frugiperda cells.
Cell motility and the cytoskeleton 1994;28(3):195-8.
1994: Kenneth S Kosik
Alzheimer's disease: which way is forward?
Neurobiology of aging 1994;15 Suppl 2():S91-2.
1993: A Watanabe; M Hasegawa; M Suzuki; Koji Takio; Maho Morishima-Kawashima; K Titani; T Arai; Kenneth S Kosik; Yasuo Ihara
In vivo phosphorylation sites in fetal and adult rat tau.
The Journal of biological chemistry 1993;268(34):25712-7.
1993: Adriana Ferreira; R Kincaid; Kenneth S Kosik
Calcineurin is associated with the cytoskeleton of cultured neurons and has a role in the acquisition of polarity.
Molecular biology of the cell 1993;4(12):1225-38.
1993: A Amaratunga; P J Morin; Kenneth S Kosik; Richard E Fine
Inhibition of kinesin synthesis and rapid anterograde axonal transport in vivo by an antisense oligonucleotide.
The Journal of biological chemistry 1993;268(23):17427-30.
1993: William R Markesbery; H Z Wang; Neil W Kowall; Kenneth S Kosik; A C McKee
Morphometric image analysis of neuropil threads in Alzheimer's disease.
Neurobiology of aging 1993;14(4):303-7.
1993: Adriana Ferreira; A Caceres; Kenneth S Kosik
Intraneuronal compartments of the amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1993;13(7):3112-23.
1993: Nicole Leclerc; Kenneth S Kosik; N Cowan; T P Pienkowski; Peter W Baas
Process formation in Sf9 cells induced by the expression of a microtubule-associated protein 2C-like construct.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(13):6223-7.
1993: A Andreadis; P E Nisson; Kenneth S Kosik; P C Watkins
The exon trapping assay partly discriminates against alternatively spliced exons.
Nucleic acids research 1993;21(9):2217-21.
1993: G F Hall; Kenneth S Kosik
Axotomy-induced neurofilament phosphorylation is inhibited in situ by microinjection of PKA and PKC inhibitors into identified lamprey neurons.
Neuron 1993;10(4):613-25.
1993: Kenneth S Kosik
The molecular and cellular biology of tau.
Brain pathology (Zurich, Switzerland) 1993;3(1):39-43.
1992: A Andreadis; William Brown; Kenneth S Kosik
Structure and novel exons of the human tau gene.
Biochemistry 1992;31(43):10626-33.
1992: A Caceres; J Mautino; Kenneth S Kosik
Suppression of MAP2 in cultured cerebellar macroneurons inhibits minor neurite formation.
Neuron 1992;9(4):607-18.
1992: J M Gallo; Diane P Hanger; E C Twist; Kenneth S Kosik; Brian H Anderton
Expression and phosphorylation of a three-repeat isoform of tau in transfected non-neuronal cells.
The Biochemical journal 1992;286 ( Pt 2)():399-404.
1992: Stephen Cheley; Kenneth S Kosik; P Paskevich; S Bakalis; Hagan Bayley
Phosphorylated baculovirus p10 is a heat-stable microtubule-associated protein associated with process formation in Sf9 cells.
Journal of cell science 1992;102 ( Pt 4)():739-52.
1992: Kenneth S Kosik
Alzheimer's disease: a cell biological perspective.
Science (New York, N.Y.) 1992;256(5058):780-3.
1992: Adriana Ferreira; J Niclas; Ronald D Vale; Gary Banker; Kenneth S Kosik
Suppression of kinesin expression in cultured hippocampal neurons using antisense oligonucleotides.
The Journal of cell biology 1992;117(3):595-606.
1992: Kenneth S Kosik
Cellular aspects of Alzheimer neurofibrillary pathology.
Progress in clinical and biological research 1992;379():183-93.
1991: Peter W Baas; T P Pienkowski; Kenneth S Kosik
Processes induced by tau expression in Sf9 cells have an axon-like microtubule organization.
The Journal of cell biology 1991;115(5):1333-44.
1991: A C McKee; Kenneth S Kosik; Neil W Kowall
Neuritic pathology and dementia in Alzheimer's disease.
Annals of neurology 1991;30(2):156-65.
1991: MM Oblinger; A Argasinski; J Wong; Kenneth S Kosik
Tau gene expression in rat sensory neurons during development and regeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(8):2453-9.
1991: J Knops; Kenneth S Kosik; Gloria Lee; J D Pardee; L Cohen-Gould; Lisa McConlogue
Overexpression of tau in a nonneuronal cell induces long cellular processes.
The Journal of cell biology 1991;114(4):725-33.
1991: M Morishima-Kawashima; T Arai; M Ogawara; Koji Takio; K Titani; T Saitoh; Kenneth S Kosik; Yasuo Ihara
A possible fetal antigen of Mr 70,000 in neurofibrillary tangles.
Brain research 1991;554(1-2):316-20.
1991: G F Hall; Virginia M-Y Lee; Kenneth S Kosik
Microtubule destabilization and neurofilament phosphorylation precede dendritic sprouting after close axotomy of lamprey central neurons.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(11):5016-20.
1991: A Caceres; S Potrebic; Kenneth S Kosik
The effect of tau antisense oligonucleotides on neurite formation of cultured cerebellar macroneurons.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1991;11(6):1515-23.
1991: Kenneth S Kosik
Alzheimer plaques and tangles: advances on both fronts.
Trends in neurosciences 1991;14(6):218-9.
1991: Barbara R Talamo; W H Feng; M Perez-Cruet; L Adelman; Kenneth S Kosik; M Y Lee; L C Cork; John S Kauer
Pathologic changes in olfactory neurons in Alzheimer's disease.
Annals of the New York Academy of Sciences 1991;640():1-7.
1991: Kenneth S Kosik; A Caceres
Tau protein and the establishment of an axonal morphology.
Journal of cell science. Supplement 1991;15():69-74.
1990: K Uéda; Eliezer Masliah; T Saitoh; S L Bakalis; H Scoble; Kenneth S Kosik
Alz-50 recognizes a phosphorylated epitope of tau protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1990;10(10):3295-304.
1990: Kenneth S Kosik
Tau protein and neurodegeneration.
Molecular neurobiology 1990;4(3-4):171-9.
1990: Kenneth S Kosik; L D Orecchio; Bruce J Schnapp; H Inouye; Rachael L Neve
The primary structure and analysis of the squid kinesin heavy chain.
The Journal of biological chemistry 1990;265(6):3278-83.
1990: Kenneth S Kosik
Tau protein and Alzheimer's disease.
Current opinion in cell biology 1990;2(1):101-4.
1990: A Caceres; Kenneth S Kosik
Inhibition of neurite polarity by tau antisense oligonucleotides in primary cerebellar neurons.
Nature 1990;343(6257):461-3.
1990: A C McKee; Kenneth S Kosik; M B Kennedy; Neil W Kowall
Hippocampal neurons predisposed to neurofibrillary tangle formation are enriched in type II calcium/calmodulin-dependent protein kinase.
Journal of neuropathology and experimental neurology 1990;49(1):49-63.
1990: Dennis J Selkoe; Marcia B Podlisny; A Gronbeck; ANDREW MAMMEN; Kenneth S Kosik
Molecular relation of amyloid filaments and paired helical filaments in Alzheimer's disease.
Advances in neurology 1990;51():171-9.
1989: A C McKee; Neil W Kowall; Kenneth S Kosik
Microtubular reorganization and dendritic growth response in Alzheimer's disease.
Annals of neurology 1989;26(5):652-9.
1989: Kenneth S Kosik; J E Crandall; Elliott J Mufson; R L Neve
Tau in situ hybridization in normal and Alzheimer brain: localization in the somatodendritic compartment.
Annals of neurology 1989;26(3):352-61.
1989: Gloria Lee; Rachael L Neve; Kenneth S Kosik
The microtubule binding domain of tau protein.
Neuron 1989;2(6):1615-24.
1989: Kenneth S Kosik
The molecular and cellular pathology of Alzheimer neurofibrillary lesions.
Journal of gerontology 1989;44(3):B55-8.
1989: Kenneth S Kosik; L D Orecchio; S Bakalis; Rachael L Neve
Developmentally regulated expression of specific tau sequences.
Neuron 1989;2(4):1389-97.
1989: Barbara R Talamo; R Rudel; Kenneth S Kosik; Virginia M-Y Lee; S Neff; L Adelman; John S Kauer
Pathological changes in olfactory neurons in patients with Alzheimer's disease.
Nature 1989;337(6209):736-9.
1989: S K Shankar; R Yanagihara; R M Garruto; Inge Grundke-Iqbal; Kenneth S Kosik; D Carleton Gajdusek
Immunocytochemical characterization of neurofibrillary tangles in amyotrophic lateral sclerosis and parkinsonism-dementia of Guam.
Annals of neurology 1989;25(2):146-51.
1989: Kenneth S Kosik
Pyramidal cell topography of microtubule-associated proteins and their precipitation into paired helical filaments.
Annals of the New York Academy of Sciences 1989;568():125-30.
1989: Kenneth S Kosik; Neil W Kowall; A McKee
Along the way to a neurofibrillary tangle: a look at the structure of tau.
Annals of medicine 1989;21(2):109-12.
1988: Kenneth S Kosik; L D Orecchio; L Binder; John Q Trojanowski; Virginia M-Y Lee; Gloria Lee
Epitopes that span the tau molecule are shared with paired helical filaments.
Neuron 1988;1(9):817-25.
1988: Kenneth S Kosik; L D Orecchio; S Bakalis; L Duffy; Rachael L Neve
Partial sequence of MAP2 in the region of a shared epitope with Alzheimer neurofibrillary tangles.
Journal of neurochemistry 1988;51(2):587-98.
1988: K B Sims; J E Crandall; Kenneth S Kosik; R S Williams
Microtubule-associated protein 2 (MAP 2) immunoreactivity in human fetal neocortex.
Brain research 1988;449(1-2):192-200.
1988: N Nukina; Kenneth S Kosik; Dennis J Selkoe
The monoclonal antibody, Alz 50, recognizes tau proteins in Alzheimer's disease brain.
Neuroscience letters 1988;87(3):240-6.
1988: Kenneth S Kosik; L D Orecchio; G A Bruns; Larry I Benowitz; G P MacDonald; D R Cox; Rachael L Neve
Human GAP-43: its deduced amino acid sequence and chromosomal localization in mouse and human.
Neuron 1988;1(2):127-32.
1987: Itzhak Fischer; Kenneth S Kosik; V S Sapirstein
Heterogeneity of microtubule-associated protein (MAP2) in vertebrate brains.
Brain research 1987;436(1):39-48.
1987: Neil W Kowall; Kenneth S Kosik
Axonal disruption and aberrant localization of tau protein characterize the neuropil pathology of Alzheimer's disease.
Annals of neurology 1987;22(5):639-43.
1987: Catherine Joachim; J H Morris; Dennis J Selkoe; Kenneth S Kosik
Tau epitopes are incorporated into a range of lesions in Alzheimer's disease.
Journal of neuropathology and experimental neurology 1987;46(6):611-22.
1987: Catherine Joachim; J H Morris; Kenneth S Kosik; Dennis J Selkoe
Tau antisera recognize neurofibrillary tangles in a range of neurodegenerative disorders.
Annals of neurology 1987;22(4):514-20.
1987: Kenneth S Kosik; E A Finch
MAP2 and tau segregate into dendritic and axonal domains after the elaboration of morphologically distinct neurites: an immunocytochemical study of cultured rat cerebrum.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1987;7(10):3142-53.
1987: N Nukina; Kenneth S Kosik; Dennis J Selkoe
Recognition of Alzheimer paired helical filaments by monoclonal neurofilament antibodies is due to crossreaction with tau protein.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(10):3415-9.
1987: P G Galloway; George Perry; Kenneth S Kosik; P Gambetti
Hirano bodies contain tau protein.
Brain research 1987;403(2):337-40.
1987: Kenneth S Kosik; Joseph Rogers; Neil W Kowall
Senile plaques are located between apical dendritic clusters.
Journal of neuropathology and experimental neurology 1987;46(1):1-11.
1986: R L Neve; P Harris; Kenneth S Kosik; D M Kurnit; T A Donlon
Identification of cDNA clones for the human microtubule-associated protein tau and chromosomal localization of the genes for tau and microtubule-associated protein 2.
Brain research 1986;387(3):271-80.
1986: R L Neve; Dennis J Selkoe; D M Kurnit; Kenneth S Kosik
A cDNA for a human microtubule associated protein 2 epitope in the Alzheimer neurofibrillary tangle.
Brain research 1986;387(2):193-6.
1986: J E Crandall; M Jacobson; Kenneth S Kosik
Ontogenesis of microtubule-associated protein 2 (MAP2) in embryonic mouse cortex.
Brain research 1986;393(1):127-33.
1986: Kenneth S Kosik; C L Joachim; Dennis J Selkoe
Microtubule-associated protein tau (tau) is a major antigenic component of paired helical filaments in Alzheimer disease.
Proceedings of the National Academy of Sciences of the United States of America 1986;83(11):4044-8.
1986: M I Escobar; H Pimienta; V S Caviness; M Jacobson; J E Crandall; Kenneth S Kosik
Architecture of apical dendrites in the murine neocortex: dual apical dendritic systems.
Neuroscience 1986;17(4):975-89.
1986: I Fischer; Thomas B Shea; V S Sapirstein; Kenneth S Kosik
Expression and distribution of microtubule-associated protein 2 (MAP2) in neuroblastoma and primary neuronal cells.
Brain research 1986;390(1):99-109.
1986: Kenneth S Kosik; S Bakalis; L Galibert; Dennis J Selkoe; L K Duffy
Age-related modifications of MAP-2.
Annals of the New York Academy of Sciences 1986;466():420-2.
1986: Kenneth S Kosik; S F Bakalis; Dennis J Selkoe; M W Pierce; L K Duffy
High molecular weight microtubule-associated proteins: purification by electro-elution and amino acid compositions.
Journal of neuroscience research 1986;15(4):543-51.
1985: Dennis J Selkoe; Carmela Abraham; C G Rasool; A McCluskey; Kenneth S Kosik; L K Duffy
Paired helical filaments in human neurons: relationship to neurofilaments.
Annals of the New York Academy of Sciences 1985;455():583-96.
1985: Kenneth S Kosik; A H McCluskey; F X Walsh; Dennis J Selkoe
Axonal transport of cytoskeletal proteins in aluminum toxicity. Aluminum toxicity and axonal transport.
Neurochemical pathology 1985;3(2):99-108.
1984: Kenneth S Kosik; L K Duffy; M M Dowling; Carmela Abraham; A McCluskey; Dennis J Selkoe
Microtubule-associated protein 2: monoclonal antibodies demonstrate the selective incorporation of certain epitopes into Alzheimer neurofibrillary tangles.
Proceedings of the National Academy of Sciences of the United States of America 1984;81(24):7941-5.
1984: Kenneth S Kosik; Dennis J Selkoe; V Sapirstein
Possible modifications of vimentin following acquisition of triton insolubility.
Biochemistry international 1984;9(4):483-90.
1983: Kenneth S Kosik; Walter G Bradley; Paul F Good; C G Rasool; Dennis J Selkoe
Cholinergic function in lumbar aluminum myelopathy.
Journal of neuropathology and experimental neurology 1983;42(4):365-75.
1982: Kenneth S Kosik; J M Gilbert; Dennis J Selkoe; P Strocchi
Characterization of postmortem human brain proteins by two-dimensional gel electrophoresis.
Journal of neurochemistry 1982;39(6):1529-38.
1982: Dennis J Selkoe; F J Salazar; Carmela Abraham; Kenneth S Kosik
Huntington's disease: changes in striatal proteins reflect astrocytic gliosis.
Brain research 1982;245(1):117-25.
1980: Kenneth S Kosik; B Furie
Thrombotic stroke associated with elevated plasma factor VIII.
Annals of neurology 1980;8(4):435-7.
1980: Kenneth S Kosik; T F Mullins; Walter G Bradley; L D Tempelis; A J Cretella
Coma and axonal degeneration in vitamin B12 deficiency.
Archives of neurology 1980;37(9):590-2.
1980: Kenneth S Kosik
Language after bilateral cerebral infarctions.
Neurology 1980;30(2):219-20.