Veli-Matti Kosma

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Närkiö-Mäkelä Mervi; Pukkila Matti; Lagerstedt Erja; Virtaniemi Jukka; Pirinen Risto; Johansson Risto; Kosunen Ari; Lappalainen Katriina; Hämäläinen Kirsi; Kosma Veli-Matti
Reduced gamma-catenin expression and poor survival in oral squamous cell carcinoma.
Hartmann-Petersen S; Tammi R H; Tammi M I; Kosma V-M
Depletion of cell surface CD44 in nonmelanoma skin tumours is associated with increased expression of matrix metalloproteinase 7.
Sallinen Hanna; Anttila Maarit; Narvainen Johanna; Koponen Jonna; Hamalainen Kirsi; Kholova Ivana; Heikura Tommi; Toivanen Pyry; Kosma Veli-Matti; Heinonen Seppo; Alitalo Kari; Yla-Herttuala Seppo
Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.

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2009: Närkiö-Mäkelä Mervi; Pukkila Matti; Lagerstedt Erja; Virtaniemi Jukka; Pirinen Risto; Johansson Risto; Kosunen Ari; Lappalainen Katriina; Hämäläinen Kirsi; Kosma Veli-Matti
Reduced gamma-catenin expression and poor survival in oral squamous cell carcinoma.
Archives of otolaryngology--head & neck surgery 2009;135(10):1035-40.
2009: Hartmann-Petersen S; Tammi R H; Tammi M I; Kosma V-M
Depletion of cell surface CD44 in nonmelanoma skin tumours is associated with increased expression of matrix metalloproteinase 7.
The British journal of dermatology 2009;160(6):1251-7.
2009: Sallinen Hanna; Anttila Maarit; Narvainen Johanna; Koponen Jonna; Hamalainen Kirsi; Kholova Ivana; Heikura Tommi; Toivanen Pyry; Kosma Veli-Matti; Heinonen Seppo; Alitalo Kari; Yla-Herttuala Seppo
Antiangiogenic gene therapy with soluble VEGFR-1, -2, and -3 reduces the growth of solid human ovarian carcinoma in mice.
Molecular therapy : the journal of the American Society of Gene Therapy 2009;17(2):278-84.
2009: Tuhkanen Hanna; Soini Ylermi; Kosma Veli-Matti; Anttila Maarit; Sironen Reijo; Hämäläinen Kirsi; Kukkonen Laura; Virtanen Ismo; Mannermaa Arto
Nuclear expression of Snail1 in borderline and malignant epithelial ovarian tumours is associated with tumour progression.
BMC cancer 2009;9():289.
2009: Nykopp Timo K; Rilla Kirsi; Sironen Reijo; Tammi Markku I; Tammi Raija H; Hämäläinen Kirsi; Heikkinen Anna-Mari; Komulainen Marja; Kosma Veli-Matti; Anttila Maarit
Expression of hyaluronan synthases (HAS1-3) and hyaluronidases (HYAL1-2) in serous ovarian carcinomas: inverse correlation between HYAL1 and hyaluronan content.
BMC cancer 2009;9():143.
2008: Kuulasmaa T; Jääskeläinen J; Suppola S; Pietiläinen T; Heikkilä P; Aaltomaa S; Kosma V-M; Voutilainen R
WNT-4 mRNA expression in human adrenocortical tumors and cultured adrenal cells.
Hormone and metabolic research = Hormon- und Stoffwechselforschung = Hormones et métabolisme 2008;40(10):668-73.
2008: Tammi Raija H; Kultti Anne; Kosma Veli-Matti; Pirinen Risto; Auvinen Päivi; Tammi Markku I
Hyaluronan in human tumors: pathobiological and prognostic messages from cell-associated and stromal hyaluronan.
Seminars in cancer biology 2008;18(4):288-95.
2008: Erkko Hannele; Dowty James G; Nikkilä Jenni; Syrjäkoski Kirsi; Mannermaa Arto; Pylkäs Katri; Southey Melissa C; Holli Kaija; Kallioniemi Anne; Jukkola-Vuorinen Arja; Kataja Vesa; Kosma Veli-Matti; Xia Bing; Livingston David M; Winqvist Robert; Hopper John L
Penetrance analysis of the PALB2 c.1592delT founder mutation.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(14):4667-71.
2008: Fagerholm Rainer; Hofstetter Barbara; Tommiska Johanna; Aaltonen Kirsimari; Vrtel Radek; Syrjäkoski Kirsi; Kallioniemi Anne; Kilpivaara Outi; Mannermaa Arto; Kosma Veli-Matti; Uusitupa Matti; Eskelinen Matti; Kataja Vesa; Aittomäki Kristiina; von Smitten Karl; Heikkilä Päivi; Lukas Jiri; Holli Kaija; Bartkova Jirina; Blomqvist Carl; Bartek Jiri; Nevanlinna Heli
NAD(P)H:quinone oxidoreductase 1 NQO1*2 genotype (P187S) is a strong prognostic and predictive factor in breast cancer.
Nature genetics 2008;40(7):844-53.
2008: Nyman H; Jantunen E; Juvonen E; Elonen E; Böhm J; Kosma V-M; Enblad G; Karjalainen-Lindsberg M-L; Leppä S
Impact of germinal center and non-germinal center phenotypes on overall and failure-free survival after high-dose chemotherapy and auto-SCT in primary diffuse large B-cell lymphoma.
Bone marrow transplantation 2008;42(2):93-8.
2008: Leinonen Tero; Pirinen Risto; Böhm Jan; Johansson Risto; Kosma Veli-Matti
Increased expression of matrix metalloproteinase-2 (MMP-2) predicts tumour recurrence and unfavourable outcome in non-small cell lung cancer.
Histology and histopathology 2008;23(6):693-700.
2008: Bergamaschi A; Tagliabue E; Sørlie T; Naume B; Triulzi T; Orlandi R; Russnes H G; Nesland J M; Tammi R; Auvinen P; Kosma V-M; Ménard S; Børresen-Dale A-L
Extracellular matrix signature identifies breast cancer subgroups with different clinical outcome.
The Journal of pathology 2008;214(3):357-67.
2008: Casalini Patrizia; Carcangiu Maria Luisa; Tammi Raija; Auvinen Päivi; Kosma Veli-Matti; Valagussa Pinuccia; Greco Marco; Balsari Andrea; Ménard Sylvie; Tagliabue Elda
Two distinct local relapse subtypes in invasive breast cancer: effect on their prognostic impact.
Clinical cancer research : an official journal of the American Association for Cancer Research 2008;14(1):25-31.
2008: Kemppainen Tarja A; Heikkinen Markku T; Ristikankare Matti K; Kosma Veli-Matti; Sontag-Strohm Tuula S; Brinck Outi; Salovaara Hannu O; Julkunen Risto J
Unkilned and large amounts of oats in the coeliac disease diet: a randomized, controlled study.
Scandinavian journal of gastroenterology 2008;43(9):1094-101.
2007: Karihtala Peeter; Soini Ylermi; Auvinen Päivi; Tammi Raija; Tammi Markku; Kosma Veli-Matti
Hyaluronan in breast cancer: correlations with nitric oxide synthases and tyrosine nitrosylation.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2007;55(12):1191-8.
2007: Hartikainen Jaana M; Mannermaa Arto; Heinonen Seppo; Kosma Veli-Matti; Kataja Vesa
A BRCA2 mutation, 4088insA, in a Finnish breast and ovarian cancer family associated with favourable clinical course.
Anticancer research 2007;27(6C):4295-300.
2007: Hartikainen J M; Kataja V; Pirskanen M; Arffman A; Ristonmaa U; Vahteristo P; Ryynänen M; Heinonen S; Kosma V-M; Mannermaa A
Screening for BRCA1 and BRCA2 mutations in Eastern Finnish breast/ovarian cancer families.
Clinical genetics 2007;72(4):311-20.
2007: Sillanpää Pia; Heikinheimo Liisa; Kataja Vesa; Eskelinen Matti; Kosma Veli-Matti; Uusitupa Matti; Vainio Harri; Metsola Katja; Hirvonen Ari
CYP1A1 and CYP1B1 genetic polymorphisms, smoking and breast cancer risk in a Finnish Caucasian population.
Breast cancer research and treatment 2007;104(3):287-97.
2007: Suhonen Kirsi A; Anttila Maarit A; Sillanpää Sari M; Hämäläinen Kirsi M; Saarikoski Seppo V; Juhola Matti; Kosma Veli-Matti
Quantification of angiogenesis by the Chalkley method and its prognostic significance in epithelial ovarian cancer.
European journal of cancer (Oxford, England : 1990) 2007;43(8):1300-7.
2007: Pellikainen Johanna M; Kosma Veli-Matti
Activator protein-2 in carcinogenesis with a special reference to breast cancer--a mini review.
International journal of cancer. Journal international du cancer 2007;120(10):2061-7.
2007: Leinonen T; Pirinen R; Böhm J; Johansson R; Rinne A; Weber E; Kosma V-M
Biological and prognostic role of acid cysteine proteinase inhibitor (ACPI, cystatin A) in non-small-cell lung cancer.
Journal of clinical pathology 2007;60(5):515-9.
2007: Anttila Maarit A; Voutilainen Kirsi; Merivalo Satu; Saarikoski Seppo; Kosma Veli-Matti
Prognostic significance of iNOS in epithelial ovarian cancer.
Gynecologic oncology 2007;105(1):97-103.
2007: Happo M S; Salonen R O; Hälinen A I; Jalava P I; Pennanen A S; Kosma V M; Sillanpää M; Hillamo R; Brunekreef B; Katsouyanni K; Sunyer J; Hirvonen M-R
Dose and time dependency of inflammatory responses in the mouse lung to urban air coarse, fine, and ultrafine particles from six European cities.
Inhalation toxicology 2007;19(3):227-46.
2007: Erkko Hannele; Xia Bing; Nikkilä Jenni; Schleutker Johanna; Syrjäkoski Kirsi; Mannermaa Arto; Kallioniemi Anne; Pylkäs Katri; Karppinen Sanna-Maria; Rapakko Katrin; Miron Alexander; Sheng Qing; Li Guilan; Mattila Henna; Bell Daphne W; Haber Daniel A; Grip Mervi; Reiman Mervi; Jukkola-Vuorinen Arja; Mustonen Aki; Kere Juha; Aaltonen Lauri A; Kosma Veli-Matti; Kataja Vesa; Soini Ylermi; Drapkin Ronny I; Livingston David M; Winqvist Robert
A recurrent mutation in PALB2 in Finnish cancer families.
Nature 2007;446(7133):316-9.
2007: Pukkila Matti; Kosunen Ari; Ropponen Kirsi; Virtaniemi Jukka; Kellokoski Jari; Kumpulainen Eero; Pirinen Risto; Nuutinen Juhani; Johansson Risto; Kosma Veli-Matti
High stromal versican expression predicts unfavourable outcome in oral squamous cell carcinoma.
Journal of clinical pathology 2007;60(3):267-72.
2007: Sillanpää S; Anttila M; Voutilainen K; Ropponen K; Turpeenniemi-Hujanen T; Puistola U; Tammi R; Tammi M; Sironen R; Saarikoski S; Kosma V-M
Prognostic significance of matrix metalloproteinase-9 (MMP-9) in epithelial ovarian cancer.
Gynecologic oncology 2007;104(2):296-303.
2007: Kemppainen Tarja; Janatuinen Esko; Holm Kati; Kosma Veli-Matti; Heikkinen Markku; Mäki Markku; Laurila Kaija; Uusitupa Matti; Julkunen Risto
No observed local immunological response at cell level after five years of oats in adult coeliac disease.
Scandinavian journal of gastroenterology 2007;42(1):54-9.
2007: Kosunen A; Pirinen R; Ropponen K; Pukkila M; Kellokoski J; Virtaniemi J; Sironen R; Juhola M; Kumpulainen E; Johansson R; Nuutinen J; Kosma V-M
CD44 expression and its relationship with MMP-9, clinicopathological factors and survival in oral squamous cell carcinoma.
Oral oncology 2007;43(1):51-9.
2007: Sillanpää S; Anttila M; Suhonen K; Hämäläinen K; Turpeenniemi-Hujanen T; Puistola U; Tammi M; Sironen R; Saarikoski S; Kosma V-M
Prognostic significance of extracellular matrix metalloproteinase inducer and matrix metalloproteinase 2 in epithelial ovarian cancer.
Tumour biology : the journal of the International Society for Oncodevelopmental Biology and Medicine 2007;28(5):280-9.
2006: Karinen Hannele; Kärkkäinen Päivi; Pihlajamäki Jussi; Janatuinen Esko; Heikkinen Markku; Julkunen Risto; Kosma Veli-Matti; Naukkarinen Anita; Laakso Markku
HLA genotyping is useful in the evaluation of the risk for coeliac disease in the 1st-degree relatives of patients with coeliac disease.
Scandinavian journal of gastroenterology 2006;41(11):1299-304.
2006: Sillanpää Sari M; Anttila Maarit A; Voutilainen Kirsi A; Ropponen Kirsi M; Sironen Reijo K; Saarikoski Serpo V; Kosma Veli-Matti
Prognostic significance of matrix metalloproteinase-7 in epithelial ovarian cancer and its relation to beta-catenin expression.
International journal of cancer. Journal international du cancer 2006;119(8):1792-9.
2006: Sallinen Hanna; Anttila Maarit; Narvainen Johanna; Ordén Maija-Riitta; Ropponen Kirsi; Kosma Veli-Matti; Heinonen Seppo; Yla-Herttuala Seppo
A highly reproducible xenograft model for human ovarian carcinoma and application of MRI and ultrasound in longitudinal follow-up.
Gynecologic oncology 2006;103(1):315-20.
2006: Tuhkanen Hanna; Anttila Maarit; Kosma Veli-Matti; Heinonen Seppo; Juhola Matti; Helisalmi Seppo; Kataja Vesa; Mannermaa Arto
Frequent gene dosage alterations in stromal cells of epithelial ovarian carcinomas.
International journal of cancer. Journal international du cancer 2006;119(6):1345-53.
2006: Voutilainen K A; Anttila M A; Sillanpää S M; Ropponen K M; Saarikoski S V; Juhola M T; Kosma V-M
Prognostic significance of E-cadherin-catenin complex in epithelial ovarian cancer.
Journal of clinical pathology 2006;59(5):460-7.
2006: Hartikainen Jaana M; Tuhkanen Hanna; Kataja Vesa; Eskelinen Matti; Uusitupa Matti; Kosma Veli-Matti; Mannermaa Arto
Refinement of the 22q12-q13 breast cancer--associated region: evidence of TMPRSS6 as a candidate gene in an eastern Finnish population.
Clinical cancer research : an official journal of the American Association for Cancer Research 2006;12(5):1454-62.
2006: Leinonen Tero; Pirinen Risto; Böhm Jan; Johansson Risto; Ropponen Kirsi; Kosma Veli-Matti
Expression of matrix metalloproteinases 7 and 9 in non-small cell lung cancer. Relation to clinicopathological factors, beta-catenin and prognosis.
Lung cancer (Amsterdam, Netherlands) 2006;51(3):313-21.
2006: Karinen Hannele; Kärkkäinen Päivi; Pihlajamäki Jussi; Janatuinen Esko; Heikkinen Markku; Julkunen Risto; Kosma Veli-Matti; Naukkarinen Anita; Laakso Markku
Gene dose effect of the DQB1*0201 allele contributes to severity of coeliac disease.
Scandinavian journal of gastroenterology 2006;41(2):191-9.
2005: Auvinen P; Tammi R; Tammi M; Johansson R; Kosma V-M
Expression of CD 44 s, CD 44 v 3 and CD 44 v 6 in benign and malignant breast lesions: correlation and colocalization with hyaluronan.
Histopathology 2005;47(4):420-8.
2005: Sillanpää Pia; Kataja Vesa; Eskelinen Matti; Kosma Veli-Matti; Uusitupa Matti; Vainio Harri; Mitrunen Katja; Hirvonen Ari
Sulfotransferase 1A1 genotype as a potential modifier of breast cancer risk among premenopausal women.
Pharmacogenetics and genomics 2005;15(10):749-52.
2005: Sillanpää Pia; Hirvonen Ari; Kataja Vesa; Eskelinen Matti; Kosma Veli-Matti; Uusitupa Matti; Vainio Harri; Mitrunen Katja
NAT2 slow acetylator genotype as an important modifier of breast cancer risk.
International journal of cancer. Journal international du cancer 2005;114(4):579-84.
2005: Pirinen Risto; Leinonen Tero; Böhm Jan; Johansson Risto; Ropponen Kirsi; Kumpulainen Eero; Kosma Veli-Matti
Versican in nonsmall cell lung cancer: relation to hyaluronan, clinicopathologic factors, and prognosis.
Human pathology 2005;36(1):44-50.
2005: Hartikainen Jaana M; Tuhkanen Hanna; Kataja Vesa; Dunning Alison M; Antoniou Antonis; Smith Paula; Arffman Airi; Pirskanen Mia; Easton Douglas F; Eskelinen Matti; Uusitupa Matti; Kosma Veli-Matti; Mannermaa Arto
An autosome-wide scan for linkage disequilibrium-based association in sporadic breast cancer cases in eastern Finland: three candidate regions found.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2005;14(1):75-80.
2005: Kemppainen T; Tammi R; Tammi M; Agren U; Julkunen R; Böhm J; Uusitupa M; Kosma V-M
Elevated expression of hyaluronan and its CD44 receptor in the duodenal mucosa of coeliac patients.
Histopathology 2005;46(1):64-72.
2005: Kosma Veli-Matti
[What is new in the biology and prognosis of breast cancer?]
Duodecim; lääketieteellinen aikakauskirja 2005;121(24):2621-2.
2005: Metsola Katja; Kataja Vesa; Sillanpää Pia; Siivola Päivi; Heikinheimo Liisa; Eskelinen Matti; Kosma Veli-Matti; Uusitupa Matti; Hirvonen Ari
XRCC1 and XPD genetic polymorphisms, smoking and breast cancer risk in a Finnish case-control study.
Breast cancer research : BCR 2005;7(6):R987-97.
2004: Gulbinowicz Monika; Berdel Bozena; Wójcik Slawomir; Dziewiatkowski Jerzy; Oikarinen Seija; Mutanen Marja; Kosma Veli-Matti; Mykkänen Hannu; Morys Janusz
Morphometric analysis of the small intestine in wild type mice C57BL/6L -- a developmental study.
Folia morphologica 2004;63(4):423-30.
2004: Pellikainen Johanna M; Ropponen Kirsi M; Kataja Vesa V; Kellokoski Jari K; Eskelinen Matti J; Kosma Veli-Matti
Expression of matrix metalloproteinase (MMP)-2 and MMP-9 in breast cancer with a special reference to activator protein-2, HER2, and prognosis.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(22):7621-8.
2004: Rioux John D; Karinen Hannele; Kocher Kerry; McMahon Sheila Guschwan; Kärkkäinen Päivi; Janatuinen Esko; Heikkinen Markku; Julkunen Risto; Pihlajamäki Jussi; Naukkarinen Anita; Kosma Veli-Matti; Daly Mark J; Lander Eric S; Laakso Markku
Genomewide search and association studies in a Finnish celiac disease population: Identification of a novel locus and replication of the HLA and CTLA4 loci.
American journal of medical genetics. Part A 2004;130A(4):345-50.
2004: Tuhkanen Hanna; Anttila Maarit; Kosma Veli-Matti; Puolakka Jukka; Juhola Matti; Heinonen Seppo; Mannermaa Arto
Marked allelic imbalance on chromosome 5q31 does not explain alpha-catenin expression in epithelial ovarian cancer.
Gynecologic oncology 2004;94(2):416-21.
2004: Aaltomaa Sirpa; Lipponen Pertti; Kärjä Vesa; Lundstedt Seppo; Lappi Jani; Kosma Veli-Matti
The expression and prognostic value of alpha-, beta- and gamma-catenins in renal cell carcinoma.
Anticancer research 2004;24(4):2407-13.
2004: Pukkila M J; Kosunen A S T; Virtaniemi J A; Kumpulainen E J; Johansson R T; Kellokoski J K; Nuutinen J; Kosma V-M
Versican expression in pharyngeal squamous cell carcinoma: an immunohistochemical study.
Journal of clinical pathology 2004;57(7):735-9.
2004: Pellikainen J; Naukkarinen A; Ropponen K; Rummukainen J; Kataja V; Kellokoski J; Eskelinen M; Kosma V-M
Expression of HER2 and its association with AP-2 in breast cancer.
European journal of cancer (Oxford, England : 1990) 2004;40(10):1485-95.
2004: Toivonen Sari; Heinonen Seppo; Anttila Maarit; Kosma Veli-Matti; Saarikoski Seppo
Obstetric prognosis after placental abruption.
Fetal diagnosis and therapy 2004;19(4):336-41.
2004: Sillanpää Pia; Hirvonen Ari; Kataja Vesa; Eskelinen Matti; Kosma Veli-Matti; Uusitupa Matti; Vainio Harri; Mitrunen Katja
Vitamin D receptor gene polymorphism as an important modifier of positive family history related breast cancer risk.
Pharmacogenetics 2004;14(4):239-45.
2004: Suwiwat Supaporn; Ricciardelli Carmela; Tammi Raija; Tammi Markku; Auvinen Paivi; Kosma Veli-Matti; LeBaron Richard G; Raymond Wendy A; Tilley Wayne D; Horsfall David J
Expression of extracellular matrix components versican, chondroitin sulfate, tenascin, and hyaluronan, and their association with disease outcome in node-negative breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(7):2491-8.
2004: Tuhkanen Hanna; Anttila Maarit; Kosma Veli-Matti; Ylä-Herttuala Seppo; Heinonen Seppo; Kuronen Arja; Juhola Matti; Tammi Raija; Tammi Markku; Mannermaa Arto
Genetic alterations in the peritumoral stromal cells of malignant and borderline epithelial ovarian tumors as indicated by allelic imbalance on chromosome 3p.
International journal of cancer. Journal international du cancer 2004;109(2):247-52.
2004: Kosunen A; Ropponen K; Kellokoski J; Pukkila M; Virtaniemi J; Valtonen H; Kumpulainen E; Johansson R; Tammi R; Tammi M; Nuutinen J; Kosma V-M
Reduced expression of hyaluronan is a strong indicator of poor survival in oral squamous cell carcinoma.
Oral oncology 2004;40(3):257-63.
2003: Julkunen Kristiina; Mäkinen Kimmo; Kärjä Vesa; Kosma Veli-Matti; Eskelinen Matti
alpha-, beta- and chi-catenin expression in human pancreatic cancer.
Anticancer research 2003;23(6D):5043-7.
2003: Sillanpää Sari; Anttila Maarit A; Voutilainen Kirsi; Tammi Raija H; Tammi Markku I; Saarikoski Seppo V; Kosma Veli-Matti
CD44 expression indicates favorable prognosis in epithelial ovarian cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2003;9(14):5318-24.
2003: Voutilainen Kirsi; Anttila Maarit; Sillanpää Sari; Tammi Raija; Tammi Markku; Saarikoski Seppo; Kosma Veli-Matti
Versican in epithelial ovarian cancer: relation to hyaluronan, clinicopathologic factors and prognosis.
International journal of cancer. Journal international du cancer 2003;107(3):359-64.
2003: Liu Jianqi; Kuulasmaa Tiina; Kosma Veli-Matti; Bützow Ralf; Vänttinen Teemu; Hydén-Granskog Christel; Voutilainen Raimo
Expression of betaglycan, an inhibin coreceptor, in normal human ovaries and ovarian sex cord-stromal tumors and its regulation in cultured human granulosa-luteal cells.
The Journal of clinical endocrinology and metabolism 2003;88(10):5002-8.
2003: Pajari Anne-Maria; Rajakangas Johanna; Päivärinta Essi; Kosma Veli-Matti; Rafter Joseph; Mutanen Marja
Promotion of intestinal tumor formation by inulin is associated with an accumulation of cytosolic beta-catenin in Min mice.
International journal of cancer. Journal international du cancer 2003;106(5):653-60.
2003: Keski-Nisula Leea T; Aalto Marja-Leena; Kirkinen Pertti P; Kosma Veli-Matti; Heinonen Seppo T
Myometrial inflammation in human delivery and its association with labor and infection.
American journal of clinical pathology 2003;120(2):217-24.
2003: Korpi A; Kasanen J-P; Kosma V-M; Rylander R; Pasanen A-L
Slight respiratory irritation but not inflammation in mice exposed to (1-->3)-beta-D-glucan aerosols.
Mediators of inflammation 2003;12(3):139-46.
2003: Hiltunen Mikko Olavi; Ruuskanen Markku; Huuskonen Jouni; Mähönen Anssi Juhani; Ahonen Mari; Rutanen Juha; Kosma Veli-Matti; Mahonen Anitta; Kröger Heikki; Ylä-Herttuala Seppo
Adenovirus-mediated VEGF-A gene transfer induces bone formation in vivo.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(9):1147-9.
2003: Heikkinen P; Kosma V-M; Alhonen L; Huuskonen H; Komulainen H; Kumlin T; Laitinen J T; Lang S; Puranen L; Juutilainen J
Effects of mobile phone radiation on UV-induced skin tumourigenesis in ornithine decarboxylase transgenic and non-transgenic mice.
International journal of radiation biology 2003;79(4):221-33.
2003: Pellikainen M J; Pekola T T; Ropponen K M; Kataja V V; Kellokoski J K; Eskelinen M J; Kosma V-M
p21WAF1 expression in invasive breast cancer and its association with p53, AP-2, cell proliferation, and prognosis.
Journal of clinical pathology 2003;56(3):214-20.
2003: Karvinen S; Kosma V-M; Tammi M I; Tammi R
Hyaluronan, CD44 and versican in epidermal keratinocyte tumours.
The British journal of dermatology 2003;148(1):86-94.
2003: Jussila J; Pelkonen J; Kosma V-M; Mäki-Paakkanen J; Komulainen H; Hirvonen M-R
Systemic immunoresponses in mice after repeated exposure of lungs to spores of Streptomyces californicus.
Clinical and diagnostic laboratory immunology 2003;10(1):30-7.
2002: Jussila Juha; Komulainen Hannu; Kosma Veli-Matti; Nevalainen Aino; Pelkonen Jukka; Hirvonen Maija-Riitta
Spores of Aspergillus versicolor isolated from indoor air of a moisture-damaged building provoke acute inflammation in mouse lungs.
Inhalation toxicology 2002;14(12):1261-77.
2002: Toivonen Sari; Heinonen Seppo; Anttila Maarit; Kosma Veli-Matti; Saarikoski Seppo
Reproductive risk factors, Doppler findings, and outcome of affected births in placental abruption: a population-based analysis.
American journal of perinatology 2002;19(8):451-60.
2002: Hiltunen Essi L J; Anttila Maarit; Kultti Anne; Ropponen Kirsi; Penttinen Jorma; Yliskoski Merja; Kuronen Arja T; Juhola Matti; Tammi Raija; Tammi Markku; Kosma Veli-Matti
Elevated hyaluronan concentration without hyaluronidase activation in malignant epithelial ovarian tumors.
Cancer research 2002;62(22):6410-3.
2002: Pellikainen Johanna; Kataja Vesa; Ropponen Kirsi; Kellokoski Jari; Pietiläinen Timo; Böhm Jan; Eskelinen Matti; Kosma Veli-Matti
Reduced nuclear expression of transcription factor AP-2 associates with aggressive breast cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(11):3487-95.
2002: Jussila Juha; Komulainen Hannu; Huttunen Kati; Roponen Marjut; Iivanainen Eila; Torkko Pirjo; Kosma Veli-Matti; Pelkonen Jukka; Hirvonen Maija-Riitta
Mycobacterium terrae isolated from indoor air of a moisture-damaged building induces sustained biphasic inflammatory response in mouse lungs.
Environmental health perspectives 2002;110(11):1119-25.
2002: Pukkila Matti J; Kumpulainen Eero J; Virtaniemi Jukka A; Johansson Risto T; Halonen Pirjo M; Kellokoski Jari K; Kosunen Ari S T; Nuutinen Juhani; Kosma Veli-Matti
Nuclear and cytoplasmic p53 expression in pharyngeal squamous cell carcinoma: prognostic implications.
Head & neck 2002;24(8):784-91.
2002: Kumlin Timo; Heikkinen Päivi; Kosma Veli-Matti; Alhonen Leena; Jänne Juhani; Juutilainen Jukka
p53-independent apoptosis in UV-irradiated mouse skin: possible inhibition by 50 Hz magnetic fields.
Radiation and environmental biophysics 2002;41(2):155-8.
2002: Pukkila Matti J; Kellokoski Jari K; Virtaniemi Jukka A; Kumpulainen Eero J; Johansson Risto T; Halonen Pirjo M; Kosunen Ari S T; Nuutinen Juhani; Kosma Veli-Matti
Inducible nitric oxide synthase expression in pharyngeal squamous cell carcinoma: relation to p53 expression, clinicopathological data, and survival.
The Laryngoscope 2002;112(6):1084-8.
2002: Korpi Anne; Kasanen J-P; Raunio P; Kosma V-M; Virtanen T; Pasanen A-L
Effects of aerosols from nontoxic Stachybotrys chartarum on murine airways.
Inhalation toxicology 2002;14(5):521-40.
2002: Hakulinen Pasi; Kosma Veli-Matti; Komulainen Hannu
Expression of p53 and p21 Ki-ras proteins in rat thyroid gland tumors induced by 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).
Anticancer research 2002;22(2A):703-6.
2002: Janatuinen E K; Kemppainen T A; Julkunen R J K; Kosma V-M; Mäki M; Heikkinen M; Uusitupa M I J
No harm from five year ingestion of oats in coeliac disease.
Gut 2002;50(3):332-5.
2002: Liu Jianqi; Kosma Veli-Matti; Vänttinen Teemu; Hydén-Granskog Christel; Voutilainen Raimo
Gonadotrophins inhibit the expression of insulin-like growth factor binding protein-related protein-2 mRNA in cultured human granulosa-luteal cells.
Molecular human reproduction 2002;8(2):136-41.
2002: Böhm Jan; Niskanen Leo; Tammi Raija; Tammi Markku; Eskelinen Matti; Pirinen Risto; Hollmen Sinikka; Alhava Esko; Kosma Veli-Matti
Hyaluronan expression in differentiated thyroid carcinoma.
The Journal of pathology 2002;196(2):180-5.
2002: Mitrunen Katja; Kataja Vesa; Eskelinen Matti; Kosma Veli-Matti; Kang Daehee; Benhamou Simone; Vainio Harri; Uusitupa Matti; Hirvonen Ari
Combined COMT and GST genotypes and hormone replacement therapy associated breast cancer risk.
Pharmacogenetics 2002;12(1):67-72.
2002: Aaltomaa S; Lipponen P; Tammi R; Tammi M; Viitanen J; Kankkunen J-P; Kosma V-M
Strong Stromal Hyaluronan Expression Is Associated with PSA Recurrence in Local Prostate Cancer.
Urologia internationalis 2002;69(4):266-72.
2001: Heikkinen P; Kosma V M; Hongisto T; Huuskonen H; Hyysalo P; Komulainen H; Kumlin T; Lahtinen T; Lang S; Puranen L; Juutilainen J
Effects of mobile phone radiation on X-ray-induced tumorigenesis in mice.
Radiation research 2001;156(6):775-85.
2001: Virtaniemi J A; Hirvikoski P P; Kumpulainen E J; Johansson R T; Kosma V M
Surgical management of irradiation failures in T1-T2 squamous cell carcinoma of the glottic larynx.
Anticancer research 2001;21(6A):4185-8.
2001: Aaltoma S H; Lipponen P K; Kosma V M
Inducible nitric oxide synthase (iNOS) expression and its prognostic value in prostate cancer.
Anticancer research 2001;21(4B):3101-6.
2001: Ropponen K M; Kellokoski J K; Pirinen R T; Moisio K I; Eskelinen M J; Alhava E M; Kosma V M
Expression of transcription factor AP-2 in colorectal adenomas and adenocarcinomas; comparison of immunohistochemistry and in situ hybridisation.
Journal of clinical pathology 2001;54(7):533-8.
2001: Mitrunen K; Jourenkova N; Kataja V; Eskelinen M; Kosma V M; Benhamou S; Kang D; Vainio H; Uusitupa M; Hirvonen A
Polymorphic catechol-O-methyltransferase gene and breast cancer risk.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(6):635-40.
2001: Heikkilä A; Hiltunen M O; Turunen M P; Keski-Nisula L; Turunen A M; Räsänen H; Rissanen T T; Kosma V M; Manninen H; Heinonen S; Ylä-Herttuala S
Angiographically guided utero-placental gene transfer in rabbits with adenoviruses, plasmid/liposomes and plasmid/polyethyleneimine complexes.
Gene therapy 2001;8(10):784-8.
2001: Pirinen R T; Hirvikoski P; Johansson R T; Hollmén S; Kosma V M
Reduced expression of alpha-catenin, beta-catenin, and gamma-catenin is associated with high cell proliferative activity and poor differentiation in non-small cell lung cancer.
Journal of clinical pathology 2001;54(5):391-5.
2001: Mitrunen K; Sillanpää P; Kataja V; Eskelinen M; Kosma V M; Benhamou S; Uusitupa M; Hirvonen A
Association between manganese superoxide dismutase (MnSOD) gene polymorphism and breast cancer risk.
Carcinogenesis 2001;22(5):827-9.
2001: Lipponen P; Aaltomaa S; Tammi R; Tammi M; Agren U; Kosma V M
High stromal hyaluronan level is associated with poor differentiation and metastasis in prostate cancer.
European journal of cancer (Oxford, England : 1990) 2001;37(7):849-56.
2001: Heikkinen P; Kosma V M; Huuskonen H; Komulainen H; Kumlin T; Penttilä I; Väänänen A; Juutilainen J
Effects of 50 Hz magnetic fields on cancer induced by ionizing radiation in mice.
International journal of radiation biology 2001;77(4):483-95.
2001: Mitrunen K; Jourenkova N; Kataja V; Eskelinen M; Kosma V M; Benhamou S; Vainio H; Uusitupa M; Hirvonen A
Glutathione S-transferase M1, M3, P1, and T1 genetic polymorphisms and susceptibility to breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2001;10(3):229-36.
2001: Aaltomaa S; Lipponen P; Ala-Opas M; Kosma V M
Expression and prognostic value of CD44 standard and variant v3 and v6 isoforms in prostate cancer.
European urology 2001;39(2):138-44.
2001: Jussila J; Komulainen H; Huttunen K; Roponen M; Hälinen A; Hyvärinen A; Kosma V M; Pelkonen J; Hirvonen M R
Inflammatory responses in mice after intratracheal instillation of spores of Streptomyces californicus isolated from indoor air of a moldy building.
Toxicology and applied pharmacology 2001;171(1):61-9.
2001: Pukkila M J; Virtaniemi J A; Kumpulainen E J; Pirinen R T; Johansson R T; Valtonen H J; Juhola M T; Kosma V M
Nuclear beta catenin expression is related to unfavourable outcome in oropharyngeal and hypopharyngeal squamous cell carcinoma.
Journal of clinical pathology 2001;54(1):42-7.
2001: Pirinen R; Tammi R; Tammi M; Hirvikoski P; Parkkinen J J; Johansson R; Böhm J; Hollmén S; Kosma V M
Prognostic value of hyaluronan expression in non-small-cell lung cancer: Increased stromal expression indicates unfavorable outcome in patients with adenocarcinoma.
International journal of cancer. Journal international du cancer 2001;95(1):12-7.
2001: Virtaniemi J A; Kumpulainen E J; Hirvikoski P P; Johansson R T; Kosma V M
The incidence and etiology of postlaryngectomy pharyngocutaneous fistulae.
Head & neck 2001;23(1):29-33.
2001: Setälä L; Lipponen P; Tammi R; Tammi M; Eskelinen M; Alhava E; Kosma V M
Expression of CD44 and its variant isoform v3 has no prognostic value in gastric cancer.
Histopathology 2001;38(1):13-20.
2001: Haapala J; Arokoski J P; Rönkkö S; Agren U; Kosma V M; Lohmander L S; Tammi M; Helminen H J; Kiviranta I
Decline after immobilisation and recovery after remobilisation of synovial fluid IL1, TIMP, and chondroitin sulphate levels in young beagle dogs.
Annals of the rheumatic diseases 2001;60(1):55-60.
2000: Virtaniemi J; Hirvikoski P; Pukkila M; Kumpulainen E; Johansson R; Kosma V M
Merkel cell carcinoma of the auricle.
European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery 2000;257(10):558-60.
2000: Viluksela M; Bager Y; Tuomisto J T; Scheu G; Unkila M; Pohjanvirta R; Flodström S; Kosma V M; Mäki-Paakkanen J; Vartiainen T; Klimm C; Schramm K W; Wärngård L; Tuomisto J
Liver tumor-promoting activity of 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD) in TCDD-sensitive and TCDD-resistant rat strains.
Cancer research 2000;60(24):6911-20.
2000: Mitrunen K; Jourenkova N; Kataja V; Eskelinen M; Kosma V M; Benhamou S; Vainio H; Uusitupa M; Hirvonen A
Steroid metabolism gene CYP17 polymorphism and the development of breast cancer.
Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2000;9(12):1343-8.
2000: Böhm J; Niskanen L; Kiraly K; Kellokoski J; Eskelinen M; Hollmen S; Alhava E; Kosma V M
Expression and prognostic value of alpha-, beta-, and gamma-catenins indifferentiated thyroid carcinoma.
The Journal of clinical endocrinology and metabolism 2000;85(12):4806-11.
2000: Ropponen K M; Kellokoski J K; Lipponen P K; Eskelinen M J; Alanne L; Alhava E M; Kosma V M
Expression of inducible nitric oxide synthase in colorectal cancer and its association with prognosis.
Scandinavian journal of gastroenterology 2000;35(11):1204-11.
2000: Aaltomaa S; Lipponen P; Viitanen J; Kankkunen J P; Ala-Opas M; Kosma V M
Prognostic value of CD44 standard, variant isoforms 3 and 6 and -catenin expression in local prostate cancer treated by radical prostatectomy.
European urology 2000;38(5):555-62.
2000: Böhm J P; Niskanen L K; Pirinen R T; Kiraly K; Kellokoski J K; Moisio K I; Eskelinen M J; Tulla H E; Hollmen S; Alhava E M; Kosma V M
Reduced CD44 standard expression is associated with tumour recurrence and unfavourable outcome in differentiated thyroid carcinoma.
The Journal of pathology 2000;192(3):321-7.
2000: Hiltunen M O; Turunen M P; Turunen A M; Rissanen T T; Laitinen M; Kosma V M; Ylä-Herttuala S
Biodistribution of adenoviral vector to nontarget tissues after local in vivo gene transfer to arterial wall using intravascular and periadventitial gene delivery methods.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(14):2230-6.
2000: Kumpulainen E J; Hirvikoski P P; Virtaniemi J A; Johansson R T; Simonen P M; Terävä M T; Asikainen R J; Nykänen K J; Kosma V
Hypothyroidism after radiotherapy for laryngeal cancer.
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology 2000;57(1):97-101.
2000: Pirinen R; Hirvikoski P; Böhm J; Kellokoski J; Moisio K; Virén M; Johansson R; Hollmén S; Kosma V M
Reduced expression of CD44v3 variant isoform is associated with unfavorable outcome in non-small cell lung carcinoma.
Human pathology 2000;31(9):1088-95.
2000: Karjalainen J M; Tammi R H; Tammi M I; Eskelinen M J; Agren U M; Parkkinen J J; Alhava E M; Kosma V M
Reduced level of CD44 and hyaluronan associated with unfavorable prognosis in clinical stage I cutaneous melanoma.
The American journal of pathology 2000;157(3):957-65.
2000: Hälinen A I; Salonen R O; Pennanen A S; Kosma V M
Combined respiratory effects of cold air with SO(2) or NO(2) in single 1-hour exposures of hyperventilating guinea pigs.
Inhalation toxicology 2000;12(8):693-713.
2000: Hälinen A I; Salonen R O; Pennanen A S; Kosma V M
Combined respiratory effects of cold air with SO(2) or NO(2) in repeated 10-minute exposures of hyperventilating guinea pigs.
Inhalation toxicology 2000;12(8):671-91.
2000: Karjalainen J M; Kellokoski J K; Mannermaa A J; Kujala H E; Moisio K I; Mitchell P J; Eskelinen M J; Alhava E M; Kosma V M
Failure in post-transcriptional processing is a possible inactivation mechanism of AP-2alpha in cutaneous melanoma.
British journal of cancer 2000;82(12):2015-21.
2000: Anttila M A; Kellokoski J K; Moisio K I; Mitchell P J; Saarikoski S; Syrjänen K; Kosma V M
Expression of transcription factor AP-2alpha predicts survival in epithelial ovarian cancer.
British journal of cancer 2000;82(12):1974-83.
2000: Lipponen P; Aaltomaa S; Kellokoski J; Ala-Opas M; Kosma V
Expression of activator protein 2 in prostate cancer is related to tumor differentiation and cell proliferation.
European urology 2000;37(5):573-8.
2000: Janatuinen E K; Kemppainen T A; Pikkarainen P H; Holm K H; Kosma V M; Uusitupa M I; Mäki M; Julkunen R J
Lack of cellular and humoral immunological responses to oats in adults with coeliac disease.
Gut 2000;46(3):327-31.
2000: Servomaa K; Kiuru A; Kosma V M; Hirvikoski P; Rytömaa T
p53 and K-ras gene mutations in carcinoma of the rectum among Finnish women.
Molecular pathology : MP 2000;53(1):24-30.
2000: Auvinen P; Tammi R; Parkkinen J; Tammi M; Agren U; Johansson R; Hirvikoski P; Eskelinen M; Kosma V M
Hyaluronan in peritumoral stroma and malignant cells associates with breast cancer spreading and predicts survival.
The American journal of pathology 2000;156(2):529-36.
2000: Dunder U; Kaartinen V; Valtonen P; Väänänen E; Kosma V M; Heisterkamp N; Groffen J; Mononen I
Enzyme replacement therapy in a mouse model of aspartylglycosaminuria.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(2):361-7.
2000: Anttila M A; Tammi R H; Tammi M I; Syrjänen K J; Saarikoski S V; Kosma V M
High levels of stromal hyaluronan predict poor disease outcome in epithelial ovarian cancer.
Cancer research 2000;60(1):150-5.
2000: Komulainen H; Hakulinen P; Servomaa K; Makkonen K; Vasara R; Mäki-Paakkanen J; Kosma V M
No consistent pattern of mutations in p53 and ras genes in liver tumors of rat treated with the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone (MX).
Environmental and molecular mutagenesis 2000;36(4):292-300.
2000: Mäkinen K; Loimas S; Kosma V M; Wahlfors J; Ylä-Herttuala S; Alhava E; Jänne J
Adenovirus-mediated gene transfer into an experimental pancreatic tumour.
Annales chirurgiae et gynaecologiae 2000;89(2):99-103.
2000: Virtaniemi J A; Hirvikoski P P; Kumpulainen E J; Johansson R T; Pukkala E; Kosma V M
Is the subsite distribution of laryngeal cancer related to smoking habits?
Acta oncologica (Stockholm, Sweden) 2000;39(1):77-9.
1999: Hirvonen M R; Ruotsalainen M; Roponen M; Hyvärinen A; Husman T; Kosma V M; Komulainen H; Savolainen K; Nevalainen A
Nitric oxide and proinflammatory cytokines in nasal lavage fluid associated with symptoms and exposure to moldy building microbes.
American journal of respiratory and critical care medicine 1999;160(6):1943-6.
1999: Böhm J; Kosma V M; Eskelinen M; Hollmen S; Niskanen M; Tulla H; Alhava E; Niskanen L
Non-suppressed thyrotropin and elevated thyroglobulin are independent predictors of recurrence in differentiated thyroid carcinoma.
European journal of endocrinology / European Federation of Endocrine Societies 1999;141(5):460-7.
1999: Keskikuru R; Kataja V; Kosma V M; Eskelinen M; Uusitupa M; Johansson R; Risteli L; Risteli J; Jukkola A
Preoperative high type I collagen degradation marker ICTP reflects advanced breast cancer.
Anticancer research 1999;19(5C):4481-4.
1999: Korpi A; Kasanen J P; Alarie Y; Kosma V M; Pasanen A L
Sensory irritating potency of some microbial volatile organic compounds (MVOCs) and a mixture of five MVOCs.
Archives of environmental health 1999;54(5):347-52.
1999: Kemppainen T; Kröger H; Janatuinen E; Arnala I; Lamberg-Allardt C; Kärkkäinen M; Kosma V M; Julkunen R; Jurvelin J; Alhava E; Uusitupa M
Bone recovery after a gluten-free diet: a 5-year follow-up study.
Bone 1999;25(3):355-60.
1999: Ropponen K M; Kellokoski J K; Lipponen P K; Pietiläinen T; Eskelinen M J; Alhava E M; Kosma V M
p22/WAF1 expression in human colorectal carcinoma: association with p53, transcription factor AP-2 and prognosis.
British journal of cancer 1999;81(1):133-40.
1999: Aaltomaa S; Lipponen P; Ala-Opas M; Eskelinen M; Syrjänen K; Kosma V M
Expression of cyclins A and D and p21(waf1/cip1) proteins in renal cell cancer and their relation to clinicopathological variables and patient survival.
British journal of cancer 1999;80(12):2001-7.
1999: Eskelinen M; Kataja V; Hämäläinen E; Kosma V M
Receiver-operating characteristic (ROC) curve analysis of cathepsin D and pS2 in breast disease; results from a prospective study.
Anticancer research 1999;19(4C):3463-7.
1999: Hirvikoski P; Kellokoski J K; Kumpulainen E J; Virtaniemi J A; Johansson R T; Kosma V M
Downregulation of p21/WAF1 is related to advanced and dedifferentiated laryngeal squamous cell carcinoma.
Journal of clinical pathology 1999;52(6):440-4.
1999: Aaltomaa S; Lipponen P; Ala-Opas M; Eskelinen M; Kosma V M
Alpha-catenin expression has prognostic value in local and locally advanced prostate cancer.
British journal of cancer 1999;80(3-4):477-82.
1999: Kasanen J P; Pasanen A L; Pasanen P; Liesivuori J; Kosma V M; Alarie Y
Evaluation of sensory irritation of delta3-carene and turpentine, and acceptable levels of monoterpenes in occupational and indoor environment.
Journal of toxicology and environmental health. Part A 1999;57(2):89-114.
1999: Anttila M A; Kosma V M; Hongxiu J; Puolakka J; Juhola M; Saarikoski S; Syrjänen K
p21/WAF1 expression as related to p53, cell proliferation and prognosis in epithelial ovarian cancer.
British journal of cancer 1999;79(11-12):1870-8.
1999: Romppanen J; Keskikuru R; Kataja V; Eskelinen M; Kosma V M; Savolainen K; Uusitupa M; Mononen I
Measurement of prostate-specific antigen in detection of benign or malignant breast disease in women.
British journal of cancer 1999;79(9-10):1583-7.
1999: Setälä L P; Tammi M I; Tammi R H; Eskelinen M J; Lipponen P K; Agren U M; Parkkinen J; Alhava E M; Kosma V M
Hyaluronan expression in gastric cancer cells is associated with local and nodal spread and reduced survival rate.
British journal of cancer 1999;79(7-8):1133-8.
1999: Kemppainen T; Kröger H; Janatuinen E; Arnala I; Kosma V M; Pikkarainen P; Julkunen R; Jurvelin J; Alhava E; Uusitupa M
Osteoporosis in adult patients with celiac disease.
Bone 1999;24(3):249-55.
1999: Hirvikoski P; Kumpulainen E; Virtaniemi J; Pirinen R; Salmi L; Halonen P; Johansson R; Kosma V M
Enhanced apoptosis correlates with poor survival in patients with laryngeal cancer but not with cell proliferation, bcl-2 or p53 expression.
European journal of cancer (Oxford, England : 1990) 1999;35(2):231-7.
1999: Karjalainen J M; Eskelinen M J; Kellokoski J K; Reinikainen M; Alhava E M; Kosma V M
p21(WAF1/CIP1) expression in stage I cutaneous malignant melanoma: its relationship with p53, cell proliferation and survival.
British journal of cancer 1999;79(5-6):895-902.
1999: Ropponen K M; Eskelinen M J; Lipponen P K; Alhava E M; Kosma V M
Reduced expression of alpha catenin is associated with poor prognosis in colorectal carcinoma.
Journal of clinical pathology 1999;52(1):10-6.
1999: Hirvikoski P; Auvinen A; Servomaa K; Kiuru A; Rytömaa T; Makkonen K; Kosma V M
K-ras and p53 mutations and overexpressions as prognostic factors in female rectal carcinoma.
Anticancer research 1999;19(1B):685-91.
1999: Hirvikoski P; Tammi R; Kumpulainen E; Virtaniemi J; Parkkinen J J; Tammi M; Johansson R; Agren U; Karhunen J; Kosma V M
Irregular expression of hyaluronan and its CD44 receptor is associated with metastatic phenotype in laryngeal squamous cell carcinoma.
Virchows Archiv : an international journal of pathology 1999;434(1):37-44.
1999: Virtaniemi J A; Hirvikoski P P; Kumpulainen E J; Johansson R T; Kosma V M
Laterality of laryngeal cancer.
Acta oncologica (Stockholm, Sweden) 1999;38(5):666.
1999: Kosma V M; Lang P S; Servomaa M K; Leszczynski D; Rytömaa T J
Association of p53, K-ras and proliferating cell nuclear antigen with rat lung lesions following exposure to simulated nuclear fuel particles.
Cancer detection and prevention 1999;23(3):194-203.
1998: Karjalainen J M; Kellokoski J K; Eskelinen M J; Alhava E M; Kosma V M
Downregulation of transcription factor AP-2 predicts poor survival in stage I cutaneous malignant melanoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(11):3584-91.
1998: Lipponen P; Aaltoma S; Kosma V M; Ala-Opas M; Eskelinen M
Expression of CD44 standard and variant-v6 proteins in transitional cell bladder tumours and their relation to prognosis during a long-term follow-up.
The Journal of pathology 1998;186(2):157-64.
1998: Hirvikoski P; Kumpulainen E J; Virtaniemi J A; Helin H J; Rantala I; Johansson R T; Juhola M; Kosma V M
Cytoplasmic accumulation of alpha-catenin is associated with aggressive features in laryngeal squamous-cell carcinoma.
International journal of cancer. Journal international du cancer 1998;79(5):546-50.
1998: Lipponen P; Aaltomaa S; Eskelinen M; Ala-Opas M; Kosma V M
Expression of p21(waf1/cip1) protein in transitional cell bladder tumours and its prognostic value.
European urology 1998;34(3):237-43.
1998: Anttila M; Kosma V M; Ji H; Wei-Ling X; Puolakka J; Juhola M; Saarikoski S; Syrjänen K
Clinical significance of alpha-catenin, collagen IV, and Ki-67 expression in epithelial ovarian cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1998;16(8):2591-600.
1998: Kasanen J P; Pasanen A L; Pasanen P; Liesivuori J; Kosma V M; Alarie Y
Stereospecificity of the sensory irritation receptor for nonreactive chemicals illustrated by pinene enantiomers.
Archives of toxicology 1998;72(8):514-23.
1998: Karjalainen J M; Eskelinen M J; Nordling S; Lipponen P K; Alhava E M; Kosma V M
Mitotic rate and S-phase fraction as prognostic factors in stage I cutaneous malignant melanoma.
British journal of cancer 1998;77(11):1917-25.
1998: Pirinen R T; Tammi R H; Tammi M I; Pääkkö P K; Parkkinen J J; Agren U M; Johansson R T; Viren M M; Törmänen U; Soini Y M; Kosma V M
Expression of hyaluronan in normal and dysplastic bronchial epithelium and in squamous cell carcinoma of the lung.
International journal of cancer. Journal international du cancer 1998;79(3):251-5.
1998: Väätäinen U; Lohmander L S; Thonar E; Hongisto T; Agren U; Rönkkö S; Jaroma H; Kosma V M; Tammi M; Kiviranta I
Markers of cartilage and synovial metabolism in joint fluid and serum of patients with chondromalacia of the patella.
Osteoarthritis and cartilage / OARS, Osteoarthritis Research Society 1998;6(2):115-24.
1998: Ropponen K M; Eskelinen M J; Lipponen P K; Alhava E; Kosma V M
Expression of CD44 and variant proteins in human colorectal cancer and its relevance for prognosis.
Scandinavian journal of gastroenterology 1998;33(3):301-9.
1998: Mäkinen K; Loimas S; Kosma V M; Wahlfors J; Pettengill O S; Longnecker D S; Johansson R; Alhava E
Azaserine-induced rat pancreas tumor model with transplantable cultured cells.
Pancreas 1998;16(2):160-4.
1998: Kemppainen T A; Kosma V M; Janatuinen E K; Julkunen R J; Pikkarainen P H; Uusitupa M I
Nutritional status of newly diagnosed celiac disease patients before and after the institution of a celiac disease diet--association with the grade of mucosal villous atrophy.
The American journal of clinical nutrition 1998;67(3):482-7.
1998: Kumlin T; Kosma V M; Alhonen L; Jänne J; Komulainen H; Lang S; Rytömaa T; Servomaa K; Juutilainen J
Effects of 50 Hz magnetic fields on UV-induced skin tumourigenesis in ODC-transgenic and non-transgenic mice.
International journal of radiation biology 1998;73(1):113-21.
1998: Ropponen K; Tammi M; Parkkinen J; Eskelinen M; Tammi R; Lipponen P; Agren U; Alhava E; Kosma V M
Tumor cell-associated hyaluronan as an unfavorable prognostic factor in colorectal cancer.
Cancer research 1998;58(2):342-7.
1998: Setälä L; Kosma V M; Lipponen P; Naukkarinen A; Nordling S; Hollmén S; Eskelinen M; Syrjänen K; Alhava E
Clinical relevance of p53 index and expression of proliferating cell nuclear antigen and Ki-67 in gastric cancer.
Journal of cancer research and clinical oncology 1998;124(9):497-502.
1998: Kumlin T; Alhonen L; Jänne J; Lang S; Kosma V M; Juutilainen J
Epidermal ornithine decarboxylase and polyamines in mice exposed to 50 Hz magnetic fields and UV radiation.
Bioelectromagnetics 1998;19(6):388-91.
1997: Setälä L P; Nordling S; Kosma V M; Lipponen P K; Eskelinen M J; Hollmén S M; Syrjänen K J; Alhava E M
Comparison of DNA ploidy and S-phase fraction with prognostic factors in gastric cancer.
Analytical and quantitative cytology and histology / the International Academy of Cytology [and] American Society of Cytology 1997;19(6):524-32.
1997: Hietala K A; Kosma V M; Syrjänen K J; Syrjänen S M; Kellokoski J K
Correlation of MIB-1 antigen expression with transcription factors Skn-1, Oct-1, AP-2, and HPV type in cervical intraepithelial neoplasia.
The Journal of pathology 1997;183(3):305-10.
1997: Auvinen P K; Parkkinen J J; Johansson R T; Agren U M; Tammi R H; Eskelinen M J; Kosma V M
Expression of hyaluronan in benign and malignant breast lesions.
International journal of cancer. Journal international du cancer 1997;74(5):477-81.
1997: Hirvikoski P; Kumpulainen E; Virtaniemi J; Johansson R; Haapasalo H; Marin S; Halonen P; Helin H; Raitiola H; Pukander J; Kellokumpu-Lehtinen P; Kosma V M
p53 expression and cell proliferation as prognostic factors in laryngeal squamous cell carcinoma.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(9):3111-20.
1997: Ropponen K M; Eskelinen M J; Lipponen P K; Alhava E; Kosma V M
Prognostic value of tumour-infiltrating lymphocytes (TILs) in colorectal cancer.
The Journal of pathology 1997;182(3):318-24.
1997: Komulainen H; Kosma V M; Vaittinen S L; Vartiainen T; Kaliste-Korhonen E; Lötjönen S; Tuominen R K; Tuomisto J
Carcinogenicity of the drinking water mutagen 3-chloro-4-(dichloromethyl)-5-hydroxy-2(5H)-furanone in the rat.
Journal of the National Cancer Institute 1997;89(12):848-56.
1997: Eskelinen M; Kataja V; Hämäläinen E; Kosma V M; Penttilä I; Alhava E
Serum tumour markers CEA, AFP, CA 15-3, TPS and Neu in diagnosis of breast cancer.
Anticancer research 1997;17(2B):1231-4.
1997: Hiltunen M O; Alhonen L; Koistinaho J; Myöhänen S; Pääkkönen M; Marin S; Kosma V M; Jänne J
Hypermethylation of the APC (adenomatous polyposis coli) gene promoter region in human colorectal carcinoma.
International journal of cancer. Journal international du cancer 1997;70(6):644-8.
1997: Setälä L; Lipponen P; Kosma V M; Marin S; Eskelinen M; Syrjänen K; Alhava E
Nuclear morphometry as a predictor of disease outcome in gastric cancer.
The Journal of pathology 1997;181(1):46-50.
1997: Hiltunen M O; Koistinaho J; Alhonen L; Myöhänen S; Marin S; Kosma V M; Pääkkönen M; Jänne J
Hypermethylation of the WT1 and calcitonin gene promoter regions at chromosome 11p in human colorectal cancer.
British journal of cancer 1997;76(9):1124-30.
1996: Ropponen K; Eskelinen M; Kosma V M; Lipponen P; Paakkinen P; Alhava E
Comparison of classic and quantitative prognostic factors in colorectal cancer.
Anticancer research 1996;16(6B):3875-82.
1996: Setälä L P; Kosma V M; Marin S; Lipponen P K; Eskelinen M J; Syrjänen K J; Alhava E M
Prognostic factors in gastric cancer: the value of vascular invasion, mitotic rate and lymphoplasmacytic infiltration.
British journal of cancer 1996;74(5):766-72.
1996: Pietiläinen T; Lipponen P; Aaltomaa S; Eskelinen M; Kosma V M; Syrjänen K
The important prognostic value of Ki-67 expression as determined by image analysis in breast cancer.
Journal of cancer research and clinical oncology 1996;122(11):687-92.
1995: Pietiläinen T; Lipponen P; Aaltomaa S; Eskelinen M; Kosma V M; Syrjänen K
Expression of p53 protein has no independent prognostic value in breast cancer.
The Journal of pathology 1995;177(3):225-32.
1995: Alhonen L; Halmekytö M; Kosma V M; Wahlfors J; Kauppinen R; Jänne J
Life-long over-expression of ornithine decarboxylase (ODC) gene in transgenic mice does not lead to generally enhanced tumorigenesis or neuronal degeneration.
International journal of cancer. Journal international du cancer 1995;63(3):402-4.
1995: Lang S; Servomaa K; Kosma V M; Rytömaa T
Biokinetics of nuclear fuel compounds and biological effects of nonuniform radiation.
Environmental health perspectives 1995;103(10):920-34.
1995: Janatuinen E K; Pikkarainen P H; Kemppainen T A; Kosma V M; Järvinen R M; Uusitupa M I; Julkunen R J
A comparison of diets with and without oats in adults with celiac disease.
The New England journal of medicine 1995;333(16):1033-7.
1995: Lipponen P; Pietiläinen T; Kosma V M; Aaltomaa S; Eskelinen M; Syrjänen K
Apoptosis suppressing protein bcl-2 is expressed in well-differentiated breast carcinomas with favourable prognosis.
The Journal of pathology 1995;177(1):49-55.
1995: Pasanen M; Lang S; Kojo A; Kosma V M
Effects of simulated nuclear fuel particles on the histopathology and CYP enzymes in the rat lung and liver.
Environmental research 1995;70(2):126-33.
1995: Pietiläinen T; Lipponen P; Aaltomaa S; Eskelinen M; Kosma V M; Syrjänen K
Expression of c-myc proteins in breast cancer as related to established prognostic factors and survival.
Anticancer research 1995;15(3):959-64.
1995: Aaltonen M; Lipponen P; Kosma V M; Aaltomaa S; Syrjänen K
Prognostic value of cathepsin-D expression in female breast cancer.
Anticancer research 1995;15(3):1033-7.
1995: Pietiläinen T; Lipponen P; Aaltomaa S; Eskelinen M; Kosma V M; Syrjänen K
Expression of retinoblastoma gene protein (Rb) in breast cancer as related to established prognostic factors and survival.
European journal of cancer (Oxford, England : 1990) 1995;31A(3):329-33.
1994: Hyvönen P M; Karhi T; Kosma V M; Liimola-Luoma L; Hanhijärvi H
The influence of dichloromethylene bisphosphonate on the healing of a long bone fracture, composition of bone mineral and histology of bone in the rat.
Pharmacology & toxicology 1994;75(6):384-90.
1994: Mäkinen K; Nuutinen P; Eskelinen M; Kosma V M; Alhava E
Sapphire probe versus bare fiber in interstitial laser hyperthermia (ILH). An experimental study with Wistar rats.
Anticancer research 1994;14(3A):1023-6.
1994: Lang S; Kosma V M; Kumlin T; Hälinen A; Salonen R O; Servomaa K; Rytömaa T; Ruuskanen J
Distribution and short-term effects of intratracheally instilled neutron-irradiated UO2 particles in the rat.
Environmental research 1994;65(1):119-31.
1994: Lipponen P; Aaltomaa S; Kosma V M; Syrjänen K
Apoptosis in breast cancer as related to histopathological characteristics and prognosis.
European journal of cancer (Oxford, England : 1990) 1994;30A(14):2068-73.
1993: Aaltomaa S; Lipponen P; Papinaho S; Kosma V M
Mast cells in breast cancer.
Anticancer research 1993;13(3):785-8.
1993: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Comparison of classic and quantitative prognostic factors in hormone receptor-positive and hormone receptor-negative female breast cancer.
American journal of surgery 1993;165(3):307-11.
1993: Lang S; Kosma V M; Servomaa K; Ruuskanen J; Rytömaa T
Tumour induction in mouse epidermal cells irradiated by hot particles.
International journal of radiation biology 1993;63(3):375-81.
1993: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Predictive value of a morphometric prognostic index in female breast cancer.
Oncology 1993;50(1):57-62.
1992: Lipponen P; Papinaho S; Eskelinen M; Klemi P J; Aaltomaa S; Kosma V M; Marin S; Syrjänen K
DNA ploidy, S-phase fraction and mitotic indices as prognostic predictors of female breast cancer.
Anticancer research 1992;12(5):1533-8.
1992: Karjalainen J; Eskelinen M; Kosma V M; Lipponen P; Tuominen L; Alhava E
Clinical, histological and quantitative prognostic factors in cutaneous malignant melanoma.
Anticancer research 1992;12(5):1507-11.
1992: Lipponen P; Aaltomaa S; Eskelinen M; Kosma V M; Marin S; Syrjänen K
The changing importance of prognostic factors in breast cancer during long-term follow-up.
International journal of cancer. Journal international du cancer 1992;51(5):698-702.
1992: Eskelinen M; Lipponen P; Aaltomaa S; Kosma V M; Syrjänen K; Alhava E
Breast cancer in young women: clinical, histological and morphometric prognostic factors.
Anticancer research 1992;12(4):1237-42.
1992: Eskelinen M; Lipponen P; Papinaho S; Aaltomaa S; Kosma V M; Klemi P; Syrjänen K
DNA flow cytometry, nuclear morphometry, mitotic indices and steroid receptors as independent prognostic factors in female breast cancer.
International journal of cancer. Journal international du cancer 1992;51(4):555-61.
1992: Lipponen P; Eskelinen M; Papinaho S; Klemi P J; Aaltomaa S; Kosma V M; Marin S; Syrjänen K
Sex steroid receptors, S-phase fraction and DNA ploidy as determinants of the risk of relapse and death of female breast cancer.
Anticancer research 1992;12(3):677-82.
1992: Aaltomaa S; Lipponen P; Papinaho S; Klemi P; Kosma V M; Marin S; Eskelinen M; Alhava E; Syrjänen K
Nuclear morphometry and DNA flow cytometry as prognostic factors in female breast cancer.
The European journal of surgery = Acta chirurgica 1992;158(3):135-41.
1992: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Prediction of outcome after first recurrence of breast cancer.
The European journal of surgery = Acta chirurgica 1992;158(1):13-8.
1992: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Mitotic indexes as prognostic predictors in female breast cancer.
Journal of cancer research and clinical oncology 1992;118(1):75-81.
1992: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Prognostic factors after 5 years follow-up in female breast cancer.
Oncology 1992;49(2):93-8.
1992: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Mari S; Alhava E; Syrjänen K
Histological assessment of the prognostic factors in female breast cancer.
Oncology 1992;49(1):1-8.
1992: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Lymphocyte infiltrates as a prognostic variable in female breast cancer.
European journal of cancer (Oxford, England : 1990) 1992;28A(4-5):859-64.
1992: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Tumor size, nuclear morphometry, mitotic indices as prognostic factors in axillary-lymph-node-positive breast cancer.
European surgical research. Europäische chirurgische Forschung. Recherches chirurgicales européennes 1992;24(3):160-8.
1991: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Prognostic scores combining clinical, histological and morphometric variables in assessment of the disease outcome in female breast cancer.
International journal of cancer. Journal international du cancer 1991;49(6):886-92.
1991: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Hormone receptors as prognostic factors in female breast cancer.
Annals of medicine 1991;23(6):643-8.
1991: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Hormone receptor status and mitotic activity as risk factors for recurrence and death in female breast carcinoma.
Anticancer research 1991;11(5):1701-6.
1991: Viluksela M; Kosma V M
Dithranol (anthralin)-induced skin irritation in C57BL/6, NMRI and SENCAR mice.
Pharmacology & toxicology 1991;69(2):96-104.
1991: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
The significance of nuclear morphometric variables as prognostic predictors in breast cancer.
Anticancer research 1991;11(4):1663-9.
1991: Aaltomaa S; Lipponen P; Eskelinen M; Kosma V M; Marin S; Alhava E; Syrjänen K
Prognostic factors in axillary lymph node-negative (pN-) breast carcinomas.
European journal of cancer (Oxford, England : 1990) 1991;27(12):1555-9.
1990: Chang F; Kosunen O; Kosma V M; Syrjänen S; Lahtinen J; Syrjänen K
Verrucous carcinoma of the anus containing human papillomavirus type 16 DNA detected by in situ hybridisation: a case report.
Genitourinary medicine 1990;66(5):342-5.
1990: Lipponen P K; Kosma V M; Collan Y; Kulju T; Kosunen O; Eskelinen M
Potential of nuclear morphometry and volume-corrected mitotic index in grading transitional cell carcinoma of the urinary bladder.
European urology 1990;17(4):333-7.
1989: Jantunen E; Halinen M O; Romppanen T; Kosma V M; Collan Y
Morphometric study of human myocardium in acquired valvular diseases.
Annals of medicine 1989;21(6):435-40.
1987: Hanhijärvi H; Ylinen M; Kojo A; Kosma V M
Elimination and toxicity of perfluorooctanoic acid during subchronic administration in the Wistar rat.
Pharmacology & toxicology 1987;61(1):66-8.
1987: Jantunen E; Collan Y; Halinen M O; Kosma V M
[Cardiac amyloidosis]
Duodecim; lääketieteellinen aikakauskirja 1987;103(4):192-8.
1986: Kojo A; Hanhijärvi H; Ylinen M; Kosma V M
Toxicity and kinetics of perfluoro-octanoic acid in the Wistar rat.
Archives of toxicology. Supplement. = Archiv für Toxikologie. Supplement 1986;9():465-8.

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