Christos Kosmas

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Antineoplastic Combined Chemotherapy Protocols

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Kosmas C; Mylonakis N; Tsakonas G; Vorgias G; Karvounis N; Tsavaris N; Daladimos T; Kalinoglou N; Malamos N; Akrivos T; Karabelis A
Evaluation of the paclitaxel-ifosfamide-cisplatin (TIP) combination in relapsed and/or metastatic cervical cancer.
Tsavaris Nicolas; Lazaris Andreas; Kosmas Christos; Gouveris Panagiotis; Kavantzas Nikolaos; Kopterides Petros; Papathomas Thomas; Agrogiannis George; Zorzos Haralambos; Kyriakou Vassiliki; Patsouris Efstratios;
Topoisomerase I and IIalpha protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy.
Kosmas Christos; Tsakonas George; Evgenidi Katerina; Gassiamis Argyris; Savva Lefkothea; Mylonakis Nikolaos; Karabelis Athanasios
Malignant peripheral nerve sheath tumor in neurobifromatosis type-1: two case reports.

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2009: Kosmas C; Mylonakis N; Tsakonas G; Vorgias G; Karvounis N; Tsavaris N; Daladimos T; Kalinoglou N; Malamos N; Akrivos T; Karabelis A
Evaluation of the paclitaxel-ifosfamide-cisplatin (TIP) combination in relapsed and/or metastatic cervical cancer.
British journal of cancer 2009;101(7):1059-65.
2009: Tsavaris Nicolas; Lazaris Andreas; Kosmas Christos; Gouveris Panagiotis; Kavantzas Nikolaos; Kopterides Petros; Papathomas Thomas; Agrogiannis George; Zorzos Haralambos; Kyriakou Vassiliki; Patsouris Efstratios;
Topoisomerase I and IIalpha protein expression in primary colorectal cancer and recurrences following 5-fluorouracil-based adjuvant chemotherapy.
Cancer chemotherapy and pharmacology 2009;64(2):391-8.
2009: Kosmas Christos; Tsakonas George; Evgenidi Katerina; Gassiamis Argyris; Savva Lefkothea; Mylonakis Nikolaos; Karabelis Athanasios
Malignant peripheral nerve sheath tumor in neurobifromatosis type-1: two case reports.
Cases journal 2009;2():7612.
2009: Tsavaris Nikolas; Kavantzas Nicolaos; Tsigritis Kostantinos; Xynos Ioannis D; Papadoniou Nikitas; Lazaris Andreas; Kosmas Christos; Agrogiannis George; Dokou Anna; Felekouras Evangelos; Antoniou Efstathios; Polyzos Aris; Sarantonis John; Tsipras Heracles; Karatzas Gavrilos; Papalambros Alexandros; Patsouris Efstratios S
Evaluation of DNA ploidy in relation with established prognostic factors in patients with locally advanced (unresectable) or metastatic pancreatic adenocarcinoma: a retrospective analysis.
BMC cancer 2009;9():264.
2008: Tsavaris Nicolas; Kopterides Petros; Kosmas Christos; Efthymiou Athina; Skopelitis Hlias; Dimitrakopoulos Antonios; Pagouni Eyterpi; Pikazis Dimitrios; Zis Panagiotis-Vasilis; Koufos Christos
Gabapentin monotherapy for the treatment of chemotherapy-induced neuropathic pain: a pilot study.
Pain medicine (Malden, Mass.) 2008;9(8):1209-16.
2008: Kosmas Christos; Tsakonas George; Mylonakis Nikolaos
Treatment strategies in CNS metastases.
Expert opinion on pharmacotherapy 2008;9(12):2087-98.
2008: Tsavaris N; Kosmas C; Kopterides P; Vadiaka M; Kosmas N; Skopelitis H; Karadima D; Kolliokosta G; Tzima E; Loukeris D; Pagouni E; Batziou E; Xyla V; Koufos C
Efficacy of tropisetron in patients with advanced non-small-cell lung cancer receiving adjuvant chemotherapy with carboplatin and taxanes.
European journal of cancer care 2008;17(2):167-73.
2008: Papadoniou Nikitas; Kosmas Christos; Gennatas Kostadinos; Polyzos Aris; Mouratidou Despina; Skopelitis Elias; Tzivras Michalis; Sougioultzis Stavros; Papastratis George; Karatzas Gavrilos; Papalambros Efstathios; Tsavaris Nikolas
Prognostic factors in patients with locally advanced (unresectable) or metastatic pancreatic adenocarcinoma: a retrospective analysis.
Anticancer research 2008;28(1B):543-9.
2008: Kosmas Christos; Kallistratos Manolis S; Kopterides Petros; Syrios John; Skopelitis Helias; Mylonakis Nicolaos; Karabelis Athanasios; Tsavaris Nicolas
Cardiotoxicity of fluoropyrimidines in different schedules of administration: a prospective study.
Journal of cancer research and clinical oncology 2008;134(1):75-82.
2007: Kosmas Christos; Tsavaris Nicolas; Malamos Nikolaos; Tsakonas George; Gassiamis Argyris; Polyzos Aristidis; Mylonakis Nicolas; Karabelis Athanasios
Docetaxel-ifosfamide combination in patients with HER2-non-overexpressing advanced breast cancer failing prior anthracyclines.
Investigational new drugs 2007;25(5):463-70.
2007: Tsakonas G; Kosmas C
Integration of novel targeted therapies into the systemic treatment of breast cancer--a review.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2007;12(3):319-27.
2007: Gaglia A; Bobota A; Pectasides E; Kosmas C; Papaxoinis G; Pectasides D
Successful treatment with cyclosporine of thymoma-related aplastic anemia.
Anticancer research 2007;27(4C):3025-8.
2007: Kosmas C; Tsavaris N; Mylonakis N; Tsakonas G; Gassiamis A; Skopelitis H; Polyzos A; Malamos N; Karabelis A
Docetaxel-ifosfamide combination in patients with advanced breast cancer failing prior anthracycline-based regimens: results of a phase I-II study.
Journal of chemotherapy (Florence, Italy) 2007;19(3):322-31.
2007: Polyzos Aristides; Kosmas Christos; Tsavaris Nikolas; Toufexi Helen; Lagadas Antonios; Gogas Helen; Giannakopoulos Kostas; Kouraklis Gregory; Griniatsos John; Felekouras Evagelos; Tsigris Christos; Nikiteas Nikolas; Papadopoulos Othon; Giannopoulos Athanasios
Paclitaxel-ifosfamide-cisplatin as salvage chemotherapy in ovarian cancer patients pretreated with platinum compounds and paclitaxel.
Anticancer research 2007;27(3B):1645-51.
2007: Tsakonas George P; Kallistratos Manolis S; Balamoti Eugenia K; Gassiamis Argyris; Zizi-Sermpetzoglou Adamadia; Mylonakis Nicolas; Karabelis Athanasios; Kosmas Christos
Rare and aggressive metastatic, axial multifocal local epithelioid sarcoma associated with paraneoplastic granulocytosis and hypoglycaemia.
The lancet oncology 2007;8(1):82-4.
2007: Kosmas Christos; Tsavaris Nicolas; Syrigos Konstantinos; Koutras Angelos; Tsakonas George; Makatsoris Thomas; Mylonakis Nicolas; Karabelis Athanasios; Stathopoulos George P; Kalofonos Haralambos P
A phase I-II study of bi-weekly gemcitabine and irinotecan as second-line chemotherapy in non-small cell lung cancer after prior taxane + platinum-based regimens.
Cancer chemotherapy and pharmacology 2007;59(1):51-9.
2007: Sipsas Nikolaos V; Kosmas Christos; Ziakas Panayiotis D; Karabelis Athanasios; Vadiaka Maria; Skopelitis Elias; Kordossis Theodore; Tsavaris Nikolaos
Comparison of two oral regimens for the outpatient treatment of low-risk cancer patients with chemotherapy-induced neutropenia and fever: ciprofloxacin plus cefuroxime axetil versus ciprofloxacin plus amoxicillin/clavulanate.
Scandinavian journal of infectious diseases 2007;39(9):786-91.
2007: Tsavaris Nicolas; Kosmas Christos; Skopelitis Helias; Papadoniou Nicitas; Polyzos Aristidis; Zografos George; Adoniou Efstathios; Gryniatsos John; Felekouras Evangelos; Zacharakis Michalis; Sigala Francheska; Bacoyiannis Christos; Papastratis George; Papalambros Efstathios
Sequential administration of 5-fluorouracil (5FU)/leucovorin (LV) followed by irinotecan (CPT-11) at relapse versus CPT-11 followed by 5-FU/LV in advanced colorectal carcinoma. A phase III randomized study.
Chemotherapy 2007;53(4):282-91.
2006: Kosmas Christos; Tsavaris Nicolas
A simplified premedication protocol for one-hour paclitaxel infusion in various combinations.
Medical science monitor : international medical journal of experimental and clinical research 2006;12(11):CR462-6.
2006: Tsavaris Nicolas; Kopterides Petros; Kosmas Christos; Vadiaka Maria; Dimitrakopoulos Antonios; Scopelitis Helias; Tenta Roxanni; Vaiopoulos George; Koufos Christos
Analgesic activity of high-dose intravenous calcitonin in cancer patients with bone metastases.
Oncology reports 2006;16(4):871-5.
2006: Polyzos Aristides; Tsavaris Nikolas; Kosmas Christos; Polyzos Kostas; Giannopoulos Athanasios; Felekouras Evangelos; Nikiteas Nikolas; Kouraklis Gregory; Griniatsos John; Safioleas Michael; Stamatakos Michael; Pikoulis Emmanuel; Papachristodoulou Antonios; Gogas Helen
Subsets of patients with advanced gastric cancer responding to second-line chemotherapy with docetaxel-cisplatin.
Anticancer research 2006;26(5B):3749-53.
2006: Tsavaris Nicolas; Kopterides Petros; Kosmas Christos; Siakantaris Marina; Patsouris Evangelos; Pangalis Gerasimos
Spontaneous remission of acute myeloid leukemia associated with GnRH agonist treatment.
Leukemia & lymphoma 2006;47(3):557-60.
2006: Nikolaou Maria; Koumpou Maria; Mylonakis Nicolaos; Karabelis Athanasios; Pectasides Dimitris; Kosmas Christos
Intramedullary spinal cord metastases from atypical small cell lung cancer: a case report and literature review.
Cancer investigation 2006;24(1):46-9.
2006: Gassiamis Argyris; Tsakonas George; Soukouli Georgia; Mylonakis Nicolas; Karabelis Athanasios; Kosmas Christos
Diffuse calcification of metastases after intensive multiagent chemotherapy in widespread osteosarcoma leading to death in a 18-year-old male: report of a case and literature review.
Medical oncology (Northwood, London, England) 2006;23(4):455-62.
2005: Tsavaris Nicolas; Kosmas Christos; Kopterides Petros; Tsikalakis Dimitrios; Skopelitis Hlias; Sakelaridi Fotini; Papadoniou Nikitas; Tzivras Michalis; Balatsos Vasilios; Koufos Christos; Archimandritis Athanasios
Retinol-binding protein, acute phase reactants and Helicobacter pylori infection in patients with gastric adenocarcinoma.
World journal of gastroenterology : WJG 2005;11(45):7174-8.
2005: Tsavaris Nicolas; Kosmas Christos; Skopelitis Elias; Gennatas Kostantinos; Zorbala Alexandra; Papas Paris; Gouveris Panagiotis; Antypas George; Rokana Sofia; Tzelepis George
A phase II study of the docetaxel-carboplatin chemotherapy regimen in advanced non-small-cell lung cancer.
Lung 2005;183(6):405-16.
2005: Polyzos Aristides; Kosmas Christos; Toufexi Helen; Malamos Nicholas; Lagadas Antonios; Kosmidis Christos; Ginopoulos Panagiotis; Ziras Nicholas; Kandilis Kostas; Georgoulias Vassilis
Docetaxel in combination with irinotecan (CPT-11) in platinum-resistant paclitaxel-pretreated ovarian cancer.
Anticancer research 2005;25(5):3559-64.
2005: Tsavaris N; Kosmas C; Skopelitis H; Dimitrakopoulos A; Kopterides P; Bougas D; Stravodimos K; Mitropoulos D; Alamanis C; Giannopoulos A
Methotrexate-paclitaxel-epirubicin-carboplatin (M-TEC) combination chemotherapy in patients with advanced bladder cancer: an open label phase II study.
Journal of chemotherapy (Florence, Italy) 2005;17(4):441-8.
2005: Kosmas Christos; Tsavaris Nicolas B; Tsakonas George; Soukouli Georgia; Gassiamis Argyris; Mylonakis Nicolas; Karabelis Athanasios
Cerebrospinal fluid tumor marker levels in predicting response to treatment and survival of carcinomatous meningitis in patients with advanced breast cancer.
Medical science monitor : international medical journal of experimental and clinical research 2005;11(8):CR398-401.
2005: Tsavaris Nicolas; Kosmas Christos; Skopelitis Helias; Gouveris Panagiotis; Kopterides Petros; Loukeris Dioynissis; Sigala Frantzeska; Zorbala-Sypsa Alexandra; Felekouras Evangelos; Papalambros Efstathios
Second-line treatment with oxaliplatin, leucovorin and 5-fluorouracil in gemcitabine-pretreated advanced pancreatic cancer: A phase II study.
Investigational new drugs 2005;23(4):369-75.
2005: Tsavaris N; Kosmas C; Vadiaka M; Skopelitis E; Kopteridis P; Pamouki S; Efremidis M; Kasparian H; Moisakis I; Sakelariou D; Koufos C
5-fluorouracil cardiotoxicity is a rare, dose and schedule-dependent adverse event: a prospective study.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2005;10(2):205-11.
2005: Tsavaris N; Kosmas C; Kavantzas N; Lazaris A; Skopelitis E; Dimitrakopoulos A; Siakantaris M P; Papalambros E; Diamantis N; Patsouris E; Pangalis G A
Breast cancer following curative chemotherapy for non-Hodgkin's lymphoma and the effect of drug resistance proteins to the final outcome. A retrospective study.
Journal of B.U.ON. : official journal of the Balkan Union of Oncology 2005;10(1):71-6.
2005: Tsavaris Nicolas; Kosmas Christos; Vadiaka Maria
A simplified premedication schedule for 1-hour paclitaxel administration.
The journal of supportive oncology 2005;3(1):77-81.
2005: Kosmas Christos; Koumpou Maria; Nikolaou Maria; Katselis John; Soukouli Georgia; Markoutsaki Nina; Kostopoulou Vassiliki; Gaglia Assimina; Mylonakis Nikolaos; Karabelis Athanassios; Pectasides Dimitrios
Intramedullary spinal cord metastases in breast cancer: report of four cases and review of the literature.
Journal of neuro-oncology 2005;71(1):67-72.
2005: Kosmas Christos; Tsavaris Nicolas; Koutras Aggelos; Makatsoris Thomas; Mylonakis Nicolas; Tzelepis George; Dimitrakopoulos Antonis; Spyropoulos Konstantinos; Polyzos Aristidis; Karabelis Athanasios; Kalofonos Haralambos P
A phase II study of the docetaxel-ifosfamide-carboplatin combination in advanced non-small-cell lung cancer.
Oncology 2005;69(4):333-41.
2005: Kosmas Christos; Tsavaris Nicolas B; Soukouli Georgia; Gouveris Panagiotis; Tsakonas George; Katselis John; Alexopoulos Heraklis; Mylonakis Nicolas; Karabelis Athanasios
Changes of cerebrospinal fluid tumor marker levels may predict response to treatment and survival of carcinomatous meningitis in patients with advanced breast cancer.
Medical oncology (Northwood, London, England) 2005;22(2):123-8.
2004: Tsavaris N; Gennatas K; Kosmas C; Skopelitis H M; Gouveris P; Dimitrakopoulos A; Zacharakis M; Kouraklis G; Vasiliou J; Felekouras E; Voros D; Zografos G; Balafouta M; Paraskevaidis M; Safioleas M; Fotiadis K; Papastratis G; Karatzas G; Papalambros E
Leucovorin and fluorouracil vs levamisole and fluorouracil as adjuvant chemotherapy in rectal cancer.
Oncology reports 2004;12(4):927-32.
2004: Tsavaris N; Kosmas C; Zorzos H; Lazaris A; Vadiaka M; Dimitrakopoulos A; Siakantaris M P; Rokana S; Papalambros E; Pangalis G A; Davaris P
Breast cancer after curative chemotherapy in non-Hodgkin's lymphoma: examination of the role of drug resistance and retrospective comparison to the outcome of de novo breast cancer.
Oncology reports 2004;11(4):899-903.
2004: Tsavaris Nikolas; Kosmas Christos; Gouveris Panagiotis; Gennatas Kostadinos; Polyzos Aris; Mouratidou Despina; Tsipras Heracles; Margaris Helias; Papastratis George; Tzima Evanthia; Papadoniou Nikitas; Karatzas Gavrilos; Papalambros Efstathios
Weekly gemcitabine for the treatment of biliary tract and gallbladder cancer.
Investigational new drugs 2004;22(2):193-8.
2004: Tsavaris Nicolas; Kosmas Christos; Gouveris Panagiotis; Vadiak Maria; Dimitrakopoulos Antonis; Karadima Dimitra; Pagouni Efterpi; Panagiotakopoulos George; Tzima Evanthia; Ispoglou Sevasti; Sakelariou Dimitris; Koufos Christos
G-CSF in solid tumor chemotherapy: a tailored regimen reduces febrile neutropenia, treatment delays and direct costs.
Medical science monitor : international medical journal of experimental and clinical research 2004;10(2):PI24-8.
2004: Polyzos Aristides; Tsavaris Nicholas; Kosmas Christos; Gogas Helen; Koutinos George; Nikiteas Nicholas I; Felekouras Evangelos; Kouraklis Gregory; Papadopoulos Othon; Papachristodoulou Antonios; Stamatiadis Demetrios; Safioleas Michael; Nikou George
Weekly Gemcitabine plus Fluorouracil-Folinic Acid Given Weekly for Two Days in Patients with Advanced Pancreatic Cancer : A Phase II Study.
Clinical drug investigation 2004;24(11):661-70.
2004: Tsavaris Nick B; Katsoulas Haralabos L; Kosmas Christos; Papalambros Efstathios; Gouveris Panayiotis; Papantoniou Nikitas; Rokana Sophia; Kosmas Nicolaos; Skopeliti Margarita; Tsitsilonis Ourania E
The effect of Edrecolomab (Mo17-1A) or fluorouracil-based chemotherapy on specific immune parameters in patients with colorectal cancer. A comparative study.
Oncology 2004;67(5-6):403-10.
2003: Polyzos A; Tsavaris N; Kosmas C; Gogas H; Toufexi H; Kosmidis C; Markopoulos C; Giannopoulos A; Papadopoulos O; Stamatiadis D; Kouraklis G
Full dose paclitaxel plus vinorelbine as salvage chemotherapy in anthracycline-resistant advanced breast cancer: a phase II study.
Journal of chemotherapy (Florence, Italy) 2003;15(6):607-12.
2003: Tsavaris N; Ziras N; Kosmas C; Giannakakis T; Gouveris P; Vadiaka M; Dimitrakopoulos A; Karadima D; Rokana S; Papalambros E; Papastratis G; Margaris H; Tsipras H; Polyzos A
Two different schedules of irinotecan (CPT-11) in patients with advanced colorectal carcinoma relapsing after a 5-fluorouracil and leucovorin combination. A randomized study.
Cancer chemotherapy and pharmacology 2003;52(6):514-9.
2003: Sofroniadou S; Kosmas C; Kourelis T; Makatsoris T; Koutras A; Onienadoum A; Kalofonos H P
Absence of chemotherapy-induced alopecia with paclitaxel in a case of hypothyroidism: case report.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(11):1690-1.
2003: Pectasides Dimitrios; Mylonakis Nikolaos; Farmakis Dimitrios; Nikolaou Maria; Koumpou Maria; Katselis Ioannis; Gaglia Asimina; Kostopoulou Vassiliki; Karabelis Athanasios; Kosmas Christos
Irinotecan and gemcitabine in patients with advanced non-small cell lung cancer, previously treated with cisplatin-based chemotherapy. A phase II study.
Anticancer research 2003;23(5b):4205-11.
2003: Tsavaris Nicolas; Kosmas Christos; Vadiaka Maria; Zonios Dimitris; Papalambros Efstathios; Papantoniou Nikitas; Margaris Heraklis; Zografos George; Rokana Sofia; Retalis George; Koufos Christos
Amifostine, in a reduced dose, protects against severe diarrhea associated with weekly fluorouracil and folinic acid chemotherapy in advanced colorectal cancer: a pilot study.
Journal of pain and symptom management 2003;26(3):849-54.
2003: Tsitsilonis O E; Tsavaris N B; Kosmas C; Gouveris P; Papalambros E
Immune changes in patients with colorectal cancer treated by adjuvant therapy with monoclonal antibody 17-1A: a pilot study.
Journal of chemotherapy (Florence, Italy) 2003;15(4):387-93.
2003: Polyzos Aristides; Tsavaris Nicholas; Kosmas Christos; Gogas Helen; Vadiaka Maria; Markopoulos Christos; Giannopoulos Athanasios; Kalahanis Nicholas; Stamatiadis Demetrios; Kouraklis Gregory; Karatzas Gabriel; Liapis Christos; Syrigos Konstantinos
Docetaxel and epirubicin supported by granulocyte colony-stimulating factor first-line in advanced breast cancer.
Anticancer research 2003;23(3C):2917-23.
2003: Kosmas C; Tsavaris N; Malamos N; Stavroyianni N; Gregoriou A; Rokana S; Polyzos A
Phase I-II study of docetaxel and ifosfamide combination in patients with anthracycline pretreated advanced breast cancer.
British journal of cancer 2003;88(8):1168-74.
2003: Pectasides D; Pectasides M; Farmakis D; Bountouroglou N; Nikolaou M; Koumpou M; Mylonakis N; Kosmas C
Oxaliplatin plus high-dose leucovorin and 5-fluorouracil in pretreated advanced breast cancer: a phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2003;14(4):537-42.
2003: Kosmas Christos; Tsavaris Nicolas; Mylonakis Nicolas; Kalofonos Haralambos P
An overview of current results with the gemcitabine and docetaxel combination as initial and salvage chemotherapy regimen in advanced non-small cell lung cancer.
Critical reviews in oncology/hematology 2003;45(3):265-75.
2002: Kyriazopoulos Panayiotis; Stamatopoulos Kostas; Kosmas Christos; Belessi Chryssoula; Stavroyianni Niki; Yataganas Xenophon; Papadaki Theodora
Absence of somatic hypermutation in the open reading frame of the bcl-2 gene participating in the t(14;18) chromosomal translocation in follicular lymphoma.
Leukemia & lymphoma 2002;43(12):2391-3.
2002: Kosmas C; Malamos N A; Stefanou S; Gregoriou A; Tsavaris N
Intramedullary spinal cord metastases in breast carcinoma: report of two cases and review of the literature.
Journal of chemotherapy (Florence, Italy) 2002;14(6):631-4.
2002: Kosmas C; Stamatopoulos K; Stavroyianni N; Tsavaris N; Papadaki T
Anti-CD20-based therapy of B cell lymphoma: state of the art.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2002;16(10):2004-15.
2002: Tsavaris Nicolas; Kosmas Christos; Gennatas Kostas; Vadiaka Maria; Paliaros Platon; Dimitrakopoulos Antonis; Diamantis Theodoros; Tsipras Heraklis; Papastratis George
Etoposide added to weekly leucovorin (LV)/5-fluorouracil (5-FU) in LV/5-FU pre-treated patients with advanced colorectal cancer.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(9):PI65-9.
2002: Tsavaris N; Kosmas C; Gennatas K; Vadiaka M; Skopelitis E; Xila V; Rokana S; Margaris E; Zografos G; Papastratis G; Kouraklis G
Etoposide, leucovorin (LV) and 5-fluorouracil (5-FU) in 5-FU+LV pre-treated patients with advanced colorectal cancer.
Journal of chemotherapy (Florence, Italy) 2002;14(4):406-11.
2002: Tsavaris N; Kosmas C; Vadiaka M; Kanelopoulos P; Boulamatsis D
Immune changes in patients with advanced breast cancer undergoing chemotherapy with taxanes.
British journal of cancer 2002;87(1):21-7.
2002: Kosmas Christos; Tsavaris Nicolas; Kalofonos Haralambos P
Salvage chemotherapy with the gemcitabine/docetaxel combination in non-small cell lung cancer: an overview of recent phase II studies.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(6):PI58-63.
2002: Tsavaris Nicolas; Kosmas Christos; Vadiaka Maria; Efremidis Michalis; Zinelis Andreas; Beldecos Dimitris; Sakelariou Dimitris; Koufos Christos; Stamatelos George
Cardiotoxicity following different doses and schedules of 5-fluorouracil administration for malignancy -- a survey of 427 patients.
Medical science monitor : international medical journal of experimental and clinical research 2002;8(6):PI51-7.
2002: Tsavaris Nikolas; Kosmas Christos; Vadiaka Maria; Giannouli Stavroula; Siakantaris Marina P; Vassilakopoulos Theodoros; Pangalis Gerassimos A
Pegylated liposomal doxorubicin in the CHOP regimen for older patients with aggressive (stages III/IV) non-Hodgkin's lymphoma.
Anticancer research 2002;22(3):1845-8.
2002: Kosmas Christos; Tsavaris Nicolas B; Makatsoris Thomas; Onyenadum Adimchi; Vadiaka Maria; Stavroyianni Niki; Sepsas Evangelos; Dimitropoulos Dimitris; Rokana Sofia; Kalofonos Haralambos P
A phase I-II study of docetaxel-ifosfamide-cisplatin (DIP) combination chemotherapy regimen in advanced nonsmall cell lung cancer.
International journal of cancer. Journal international du cancer 2002;98(1):141-7.
2002: Kosmas Christos; Malamos Nikolaos A; Tsavaris Nicolas B; Stamataki Melina; Stefanou Stefanos; Gregoriou Achilleas; Rokana Sofia; Vartholomeou Maria; Antonopoulos Minas J
Leptomeningeal carcinomatosis after major remission to taxane-based front-line therapy in patients with advanced breast cancer.
Journal of neuro-oncology 2002;56(3):265-73.
2002: Tsavaris N; Kosmas C; Vadiaka M; Kontos A; Fotia M; Angelopoulou A; Vrizidis N; Soulla M; Sougioultzis S; Koufos Ch
Raltitrexed (tomudex) administration in patients failing multiple prior chemotherapy regimens in advanced colorectal cancer: a pilot study.
Investigational new drugs 2002;20(1):133-6.
2002: Tsavaris N; Karargyris G; Pikazis D; Vadiaka M; Kosmas C; Sakellaropoulos N; Vaiopoulos G
Adenocarcinoma of the colon presenting as polymyositis: case report.
Journal of chemotherapy (Florence, Italy) 2002;14(1):102-5.
2002: Kosmas Christos; Malamos Nikolaos A; Tsavaris Nikolas B; Stamataki Melina; Gregoriou Achilleas; Rokana Sofia; Vartholomeou Maria; Antonopoulos Minas J
Isolated leptomeningeal carcinomatosis (carcinomatous meningitis) after taxane-induced major remission in patients with advanced breast cancer.
Oncology 2002;63(1):6-15.
2002: Kosmas C; Agelaki S; Giannakakis Th; Mavroudis D; Kouroussis Ch; Kalbakis K; Papadouris S; Souglakos J; Malamos N; Georgoulias V
Phase I study of vinorelbine and carboplatin combination in patients with taxane and anthracycline pretreated advanced breast cancer.
Oncology 2002;62(2):103-9.
2002: Tsavaris Nicolas; Kosmas Christos; Vadiaka Maria; Koufos Christos
Raltitrexed (Tomudex) administration in patients with relapsed metastatic colorectal cancer after weekly irinotecan/5-Fluorouracil/Leucovorin chemotherapy.
BMC cancer 2002;2():2.
2001: Tsavaris N; Kosmas C; Vadiaka M; Sougioultzis S; Kontos A; Agelopoulou A; Boulamatsis D; Koufos C
Comparative study of tropisetron with the addition of dexamethasone or alprazolam in breast cancer patients receiving adjuvant chemotherapy with CEF (cyclophosphamide, epirubicin and 5-fluorouracil).
Journal of chemotherapy (Florence, Italy) 2001;13(6):641-7.
2001: Kosmas C; Tsavaris N; Vadiaka M; Stavroyianni N; Koutras A; Malamos N; Onyenadum A; Rokana S; Polyzos A; Kalofonos H P
Gemcitabine and docetaxel as second-line chemotherapy for patients with nonsmall cell lung carcinoma who fail prior paclitaxel plus platinum-based regimens.
Cancer 2001;92(11):2902-10.
2001: Kalofonos H P; Onyenadum A; Kosmas C; Koutras A; Petsas T; Efthimiou V; Koukouras D; Tzoracolefterakis E; Andrikopoulos P; Androulakis J
Mitomycin C and vinblastine in anthracycline-resistant metastatic breast cancer: a phase II study.
Tumori 2001;87(6):394-7.
2001: Belessi C; Stamatopoulos K; Stavroyianni N; Zoi K; Papadaki T; Kosmas C
Somatic hypermutation targeting to intrinsic hotspots of immunoglobulin genes in follicular lymphoma and multiple myeloma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2001;15(11):1772-8.
2001: Tsavaris N; Kosmas C; Polyzos A; Genatas K; Vadiaka M; Paliaros P; Dimitrakopoulos A; Rokana S; Karatzas G; Vachiotis P; Fotiadis K
Leucovorin + 5-fluorouracil plus dipyridamole in leucovorin + 5-fluorouracil-pretreated patients with advanced colorectal cancer: a pilot study of three different dipyridamole regimens.
Tumori 2001;87(5):303-7.
2001: Alexopoulos A; Kouroussis C; Malamos N; Kakolyris S; Kalbakis K; Kosmas C; Mavroudis D; Agelaki S; Vlachonicolis J; Sarra E; Rigatos G; Georgoulias V
Docetaxel in combination with mitoxantrone and granulocyte colony-stimulating factor as front-line chemotherapy in metastatic breast cancer: a multicenter phase II study.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 2001;12(6):793-8.
2001: Kosmas C; Tsavaris N; Panopoulos C; Vadiaka M; Stavroyianni N; Kourelis T; Malamos N; Antonopoulos M; Kalofonos H P
Gemcitabine and vinorelbine as second-line therapy in non-small-cell lung cancer after prior treatment with taxane+platinum-based regimens.
European journal of cancer (Oxford, England : 1990) 2001;37(8):972-8.
2001: Tsavaris N; Kosmas C H; Vadiaka M; Kontos A; Katsorida M; Dimitrakopoulos A; Zerai A; Koufos C H
Efficacy of ondansentron treatment for acute emesis with different dosing schedules 8 vs 32 mg. A randomized study.
Journal of experimental & clinical cancer research : CR 2001;20(1):29-34.
2001: Kosmas C; Tsavaris N B; Malamos N A; Vadiaka M; Koufos C
Phase II study of paclitaxel, ifosfamide, and cisplatin as second-line treatment in relapsed small-cell lung cancer.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 2001;19(1):119-26.
2001: Kosmas C; Tsavaris N B; Vadiaka M; Chiras T; Boletis J; Kostakis A
Extragonadal seminoma after renal transplantation and immunosuppression; treatment in the presence of renal dysfunction: a case report and literature review.
Medical oncology (Northwood, London, England) 2001;18(3):221-5.
2001: Polyzos A; Tsavaris N; Kosmas C; Arnaouti T; Kalahanis N; Tsigris C; Giannopoulos A; Karatzas G; Giannikos L; Sfikakis P P
Hypersensitivity reactions to carboplatin administration are common but not always severe: a 10-year experience.
Oncology 2001;61(2):129-33.
2000: Tsavaris N; Kosmas C; Mylonakis N; Bacoyiannis C; Kalergis G; Vadiaka M; Boulamatsis D; Iakovidis V; Kosmidis P
Parameters that influence the outcome of nausea and emesis in cisplatin based chemotherapy.
Anticancer research 2000;20(6C):4777-83.
2000: Kosmas C; Stamatopoulos K; Stavroyianni N; Zoi K; Belessi C; Viniou N; Kollia P; Yataganas X
Origin and diversification of the clonogenic cell in multiple myeloma: lessons from the immunoglobulin repertoire.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 2000;14(10):1718-26.
2000: Tsavaris N; Kosmas C; Vadiaka M; Kanelopoulos P; Kontos A; Katsorida M; Agelopoulou A; Vrizidis N; Fotia M; Papoutsis K; Koufos C
Ondansentron and dexamethasone treatment with different dosing schedules (24 versus 32 mg) in patients with non-small-cell lung cancer under cisplatin-based chemotherapy: a randomized study.
Chemotherapy 2000;46(5):364-70.
2000: Tsavaris N; Skarlos D; Bacoyiannis C; Aravantinos G; Kosmas C; Retalis G; Panopoulos C; Vadiaka M; Dimitrakopoulos A; Kostantinidis K; Mitropoulos D; Bougas D; Pantazopoulos D; Kosmidis P
Combined treatment with low-dose interferon plus vinblastine is associated with less toxicity than conventional interferon monotherapy in patients with metastatic renal cell carcinoma.
Journal of interferon & cytokine research : the official journal of the International Society for Interferon and Cytokine Research 2000;20(8):685-90.
2000: Kosmas C; Tsavaris N B; Polyzos A; Kalofonos H P; Sepsas E; Malamos N A; Vadiaka M; Dosios T; Antonopoulos M J
A phase II study of paclitaxel-ifosfamide-cisplatin combination in advanced nonsmall cell lung carcinoma.
Cancer 2000;89(4):774-82.
2000: Stamatopoulos K; Kosmas C; Belessi C; Stavroyianni N; Kyriazopoulos P; Papadaki T
Molecular insights into the immunopathogenesis of follicular lymphoma.
Immunology today 2000;21(6):298-305.
2000: Kosmas C; Malamos N A; Tsavaris N; Antonopoulos M
Chemotherapy-induced complete regression of choroidal metastases and subsequent isolated leptomeningeal carcinomatosis in advanced breast cancer: a case report and literature review.
Journal of neuro-oncology 2000;47(2):161-5.
2000: Kosmas C; Malamos N A; Antonopoulos M
Complete regression of choroidal metastases from breast cancer after docetaxel-based systemic chemotherapy.
Medical and pediatric oncology 2000;34(3):229-30.
2000: Giannakenas C; Kalofonos H P; Apostolopoulos D J; Zarakovitis J; Kosmas C; Vassilakos P J
Preliminary results of the use of Re-186-HEDP for palliation of pain in patients with metastatic bone disease.
American journal of clinical oncology 2000;23(1):83-8.
2000: Kosmas C; Tsavaris N B; Polyzos A; Malamos N A; Katsikas M; Antonopoulos M J
Phase I study of dose-escalated paclitaxel, ifosfamide, and cisplatin (PIC) combination chemotherapy in advanced solid tumours.
British journal of cancer 2000;82(2):300-7.
1999: Kosmas C; Stamatopoulos K
Immunoglobulin light chain variable region genes in multiple myeloma.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(5):827-30.
1999: Polyzos A; Tsavaris N; Kosmas C; Petrikos G; Giannikos L; Kalahanis N; Papadopoulos O; Christodoulou K; Giannakopoulos K; Veslemes M; Katsilambros N
Second-line chemotherapy with cisplatin-ifosfamide in patients with ovarian cancer previously treated with carboplatin-cyclophosphamide.
Journal of chemotherapy (Florence, Italy) 1999;11(2):144-9.
1999: Stamatopoulos K; Kosmas C; Belessi C; Kyriazopoulos P; Papadaki T; Anagnostou D; Loukopoulos D
Molecular analysis of bcl-1/IgH junctional sequences in mantle cell lymphoma: potential mechanism of the t(11;14) chromosomal translocation.
British journal of haematology 1999;105(1):190-7.
1999: Kosmas C; Stamatopoulos K; Stavroyianni N; Belessi C; Viniou N; Yataganas X
Molecular analysis of immunoglobulin genes in multiple myeloma.
Leukemia & lymphoma 1999;33(3-4):253-65.
1999: Stamatopoulos K; Kosmas C; Stavroyianni N; Belessi C; Papadaki T
Selection of immunoglobulin diversity gene reading frames in B cell lymphoproliferative disorders.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1999;13(4):601-4.
1999: Mavroudis D; Malamos N; Alexopoulos A; Kourousis C; Agelaki S; Sarra E; Potamianou A; Kosmas C; Rigatos G; Giannakakis T; Kalbakis K; Apostolaki F; Vlachonicolis J; Kakolyris S; Samonis G; Georgoulias V
Salvage chemotherapy in anthracycline-pretreated metastatic breast cancer patients with docetaxel and gemcitabine: a multicenter phase II trial. Greek Breast Cancer Cooperative Group.
Annals of oncology : official journal of the European Society for Medical Oncology / ESMO 1999;10(2):211-5.
1999: Kalofonos H P; Giannakenas C; Kosmas C; Apostolopoulos D; Onienadum A; Petsas T; Dimopoulos D; Epenetos A A; Vassilakos P J
Radioimmunoscintigraphy in patients with ovarian cancer.
Acta oncologica (Stockholm, Sweden) 1999;38(5):629-34.
1999: Polyzos A; Tsavaris N; Kosmas C; Giannikos L; Katsikas M; Kalahanis N; Karatzas G; Christodoulou K; Giannakopoulos K; Stamatiadis D; Katsilambros N
A comparative study of intraperitoneal carboplatin versus intravenous carboplatin with intravenous cyclophosphamide in both arms as initial chemotherapy for stage III ovarian cancer.
Oncology 1999;56(4):291-6.
1998: Tsavaris N; Fountzilas G; Mylonakis N; Athanassiadis A; Kosmas C; Karakousis C; Bacoyiannis C; Kosmidis P
A randomized comparative study of antiemetic prophylaxis with ondansentron in a single 32-mg loading dose versus 8 mg every 6 h in patients undergoing cisplatin-based chemotherapy.
Oncology 1998;55(6):513-6.
1998: Kosmas C; Kalofonos H P; Hird V; Epenetos A A
Monoclonal antibody targeting of ovarian carcinoma.
Oncology 1998;55(5):435-46.
1998: Tsavaris N; Mylonakis N; Bacoyiannis C; Kosmas C; Kalergis G; Iakovidis V; Tzaninis D; Kosmidis P
Factors that influence the antiemetic activity of metoclopramide to cisplatin based chemotherapy.
Oncology reports 1998;5(5):1147-55.
1998: Tsavaris N; Tentas K; Tzivras M; Kosmas C; Kalachanis N; Katsikas M; Dimitrakopoulos A; Papastratis G; Macheras A; Karatzas G; Sechas M
Combined epirubicin, 5-fluorouracil and folinic acid vs no treatment for patients with advanced pancreatic cancer: a prospective comparative study.
Journal of chemotherapy (Florence, Italy) 1998;10(4):331-7.
1998: Tsavaris N; Tsigalacis D; Kosmas C; Koufos C; Vaiopoulos G; Tzivras M; Kouraklis G; Papadimas V; Georgoulis V; Archimandritis A; Sechas M
Preliminary evaluation of the potential prognostic value of serum levels of immunoglobulins (IgA, IgM, IgG, IgE) in patients with gastric cancer.
The International journal of biological markers 1998;13(2):87-91.
1998: Kosmas C; Stamatopoulos K; Papadaki T; Belessi C; Yataganas X; Anagnostou D; Loukopoulos D
Somatic hypermutation of immunoglobulin variable region genes: focus on follicular lymphoma and multiple myeloma.
Immunological reviews 1998;162():281-92.
1998: Tsavaris N B; Kosmas C
Risk of severe acute hypersensitivity reactions after rapid paclitaxel infusion of less than 1-h duration.
Cancer chemotherapy and pharmacology 1998;42(6):509-11.
1997: Stamatopoulos K; Kosmas C; Belessi C; Papadaki T; Afendaki S; Anagnostou D; Loukopoulos D
t(14;18) chromosomal translocation in follicular lymphoma: an event occurring with almost equal frequency both at the D to J(H) and at later stages in the rearrangement process of the immunoglobulin heavy chain gene locus.
British journal of haematology 1997;99(4):866-72.
1997: Polyzos A; Tsavaris N; Veslemes M; Dardoufas K; Dosios T; Kosmas C
Chemotherapy of non small cell lung cancer. A prospectively randomized study of cisplatin-etoposide versus cisplatin-mitomycin-vinblastine.
Journal of chemotherapy (Florence, Italy) 1997;9(2):102-5.
1997: Stamatopoulos K; Kosmas C; Papadaki T; Pouliou E; Belessi C; Afendaki S; Anagnostou D; Loukopoulos D
Follicular lymphoma immunoglobulin kappa light chains are affected by the antigen selection process, but to a lesser degree than their partner heavy chains.
British journal of haematology 1997;96(1):132-46.
1997: Tsavaris N; Polyzos A; Kosmas C; Giannikos L; Gogas J
A feasibility study of 1-h paclitaxel infusion in patients with solid tumors.
Cancer chemotherapy and pharmacology 1997;40(4):353-7.
1996: Tsavaris N B; Tentas K; Kosmidis P; Mylonakis N; Sakelaropoulos N; Kosmas C; Lisaios B; Soumilas A; Mandrekois D; Tsetis A; Klonaris C
5-Fluorouracil, epirubicin, and mitomycin C versus 5-fluorouracil, epirubicin, mitomycin C, and leucovorin in advanced gastric carcinoma. A randomized trial.
American journal of clinical oncology 1996;19(5):517-21.
1996: Stamatopoulos K; Kosmas C; Stavroyianni N; Loukopoulos D
Evidence for immunoglobulin heavy chain variable region gene replacement in a patient with B cell chronic lymphocytic leukemia.
Leukemia : official journal of the Leukemia Society of America, Leukemia Research Fund, U.K 1996;10(9):1551-6.
1996: Kosmas C; Viniou N A; Stamatopoulos K; Courtenay-Luck N S; Papadaki T; Kollia P; Paterakis G; Anagnostou D; Yataganas X; Loukopoulos D
Analysis of the kappa light chain variable region in multiple myeloma.
British journal of haematology 1996;94(2):306-17.
1996: Tsavaris N; Tentas K; Kosmidis P; Mylonakis N; Sakelaropoulos N; Kosmas C; Lisaios B; Soumilas A; Mandrekas D; Tsetis A; Klonaris C
A randomized trial comparing adjuvant fluorouracil, epirubicin, and mitomycin with no treatment in operable gastric cancer.
Chemotherapy 1996;42(3):220-6.
1996: Polyzos A; Tsavaris N; Giannopoulos A; Bacoyiannis C; Papadimas V; Kalahanis N; Karatzas G; Kosmas C; Sakelaropoulos N; Archimandritis A; Papachristodoulou A; Kosmidis P
Biochemical modulation of fluorouracil: comparison of methotrexate, folinic acid, and fluorouracil versus folinic acid and fluorouracil in advanced colorectal cancer: a randomized trial.
Cancer chemotherapy and pharmacology 1996;38(3):292-7.
1995: Konstantopoulos K; Delladetsima I; Kosmas C; Androulaki A; Stamatopoulos K; Rekoumi L; Patsouris S; Loukopoulos D
Diffuse hepatic calcinosis and hypercalcemia in association with a B-cell (centroblastic) lymphoma.
American journal of hematology 1995;50(1):67.
1995: Tsavaris N; Tentas K; Bacoyiannis C; Katsikas M; Sakelaropoulos N; Kosmas C; Daliani D; Kosmidis P
5-Fluorouracil, folinic acid and cisplatin in advanced colorectal cancer: a pilot study.
Anti-cancer drugs 1995;6(4):599-603.
1995: Kosmas C; Maraveyas A; Gooden C S; Snook D; Epenetos A A
Anti-chelate antibodies after intraperitoneal yttrium-90-labeled monoclonal antibody immunoconjugates for ovarian cancer therapy.
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 1995;36(5):746-53.
1994: Kosmas C; Epenetos A A; Courtenay-Luck N S
Activation of cellular immunity after intracavitary monoclonal antibody therapy of ovarian cancer.
Cancer 1994;73(12):3000-10.
1994: Maraveyas A; Snook D; Hird V; Kosmas C; Meares C F; Lambert H E; Epenetos A A
Pharmacokinetics and toxicity of an yttrium-90-CITC-DTPA-HMFG1 radioimmunoconjugate for intraperitoneal radioimmunotherapy of ovarian cancer.
Cancer 1994;73(3 Suppl):1067-75.
1994: Kalofonos H P; Kosmas C; Hird V; Snook D E; Epenetos A A
Targeting of tumours with murine and reshaped human monoclonal antibodies against placental alkaline phosphatase: immunolocalisation, pharmacokinetics and immune response.
European journal of cancer (Oxford, England : 1990) 1994;30A(12):1842-50.
1993: Kosmas C; Linardou H; Epenetos A A
Review: advances in monoclonal antibody tumour targeting.
Journal of drug targeting 1993;1(2):81-91.
1992: Kosmas C; Epenetos A A; Courtenay-Luck N S
Effects of phorbol esters and cytokines (interleukin-2,-4, and -6) on the proliferation and surface phenotype of Epstein-Barr virus immortalised human B lymphocytes.
Leukemia & lymphoma 1992;8(1-2):109-15.
1992: Kosmas C; Snook D; Gooden C S; Courtenay-Luck N S; McCall M J; Meares C F; Epenetos A A
Development of humoral immune responses against a macrocyclic chelating agent (DOTA) in cancer patients receiving radioimmunoconjugates for imaging and therapy.
Cancer research 1992;52(4):904-11.
1991: Hird V; Verhoeyen M; Badley R A; Price D; Snook D; Kosmas C; Gooden C; Bamias A; Meares C; Lavender J P
Tumour localisation with a radioactively labelled reshaped human monoclonal antibody.
British journal of cancer 1991;64(5):911-4.
1991: Kosmas C; Epenetos A A; Courtenay-Luck N S
Patients receiving murine monoclonal antibody therapy for malignancy develop T cells that proliferate in vitro in response to these antibodies as antigens.
British journal of cancer 1991;64(3):494-500.
1990: Kalofonos H P; Kosmas C; Pawlikowska T R; Bamias A; Snook D; Dhokia B; Sivolapenko G B; Courtenay-Luck N S; Epenetos A A
Immunolocalisation of testicular tumours using radiolabelled monoclonal antibody to placental alkaline phosphatase.
The Journal of nuclear medicine and allied sciences 1990;34(4):294-8.
1990: Kosmas C; Man S; Epenetos A A; Courtenay-Luck N S
The role of humoral and cellular immunity in patients developing human anti-murine immunoglobulin antibody responses after radioimmunotherapy.
The British journal of cancer. Supplement 1990;10():85-8.
1990: Kosmas C; Kalofonos H P; Epenetos A A
Radiolabelled monoclonal antibodies in tumour diagnosis and therapy.
Developments in biological standardization 1990;71():93-102.
1989: Epenetos A A; Kosmas C
Monoclonal antibodies for imaging and therapy.
British journal of cancer 1989;59(2):152-5.

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