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Nicholas Koszewski

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TOP 3
Nicholas J Koszewski; Ronald L Horst; Jesse P Goff
Importance of apical membrane delivery of 1,25-dihydroxyvitamin D3 to vitamin D-responsive gene expression in the colon.
Jesse P Goff; Joseph S Haynes; Nicholas J Koszewski; Ronald L Horst
Targeted delivery of vitamin D to the colon using β-glucuronides of vitamin D: therapeutic effects in a murine model of inflammatory bowel disease.
Nicholas J Koszewski; Johann Herberth; Hartmut H Malluche
Retinoic acid receptor gamma 2 interactions with vitamin D response elements.

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All Publications

2012: Nicholas J Koszewski; Ronald L Horst; Jesse P Goff
Importance of apical membrane delivery of 1,25-dihydroxyvitamin D3 to vitamin D-responsive gene expression in the colon.
American journal of physiology. Gastrointestinal and liver physiology 2012;303(7):G870-8.
2012: Jesse P Goff; Joseph S Haynes; Nicholas J Koszewski; Ronald L Horst
Targeted delivery of vitamin D to the colon using β-glucuronides of vitamin D: therapeutic effects in a murine model of inflammatory bowel disease.
American journal of physiology. Gastrointestinal and liver physiology 2012;302(4):G460-9.
2010: Nicholas J Koszewski; Johann Herberth; Hartmut H Malluche
Retinoic acid receptor gamma 2 interactions with vitamin D response elements.
The Journal of steroid biochemistry and molecular biology 2010;120(4-5):200-7.
2008: Johann Herberth; Alexander P Alimov; John P Williams; Hartmut H Malluche; Nicholas J Koszewski
PTH regulation of the human cytomegalovirus immediate-early gene promoter.
Biochemical and biophysical research communications 2008;368(4):977-82.
2006: Hartmut H Malluche; Nicholas J Koszewski; Marie-Claude Monier-Faugere; John P Williams; Hanna Mawad
Influence of the parathyroid glands on bone metabolism.
European journal of clinical investigation 2006;36 Suppl 2():23-33.
2005: Alexander P Alimov; Ok-Kyong Park-Sarge; Kevin D Sarge; Hartmut H Malluche; Nicholas J Koszewski
Transactivation of the parathyroid hormone promoter by specificity proteins and the nuclear factor Y complex.
Endocrinology 2005;146(8):3409-16.
2005: Nancy G Pedigo; Hongxing Zhang; Maria E C Bruno; Charlotte S Kaetzel; Amy R Dugan; Piam Shanehsaz; Robert F Hennigan; Zhenlan Xing; Nicholas J Koszewski; David Kaetzel
A 5'-distal enhanceosome in the PDGF-A gene is activated in choriocarcinoma cells via ligand-independent binding of vitamin D receptor and constitutive jun kinase signaling.
Oncogene 2005;24(16):2654-66.
2005: Nicholas J Koszewski; Alexander P Alimov; M Chris Langub; Ok-Kyong Park-Sarge; Hartmut H Malluche
Contrasting mammalian PTH promoters: identification of transcription factors controlling PTH gene expression.
Clinical nephrology 2005;63(2):158-62.
2004: Nicholas J Koszewski; Alexander P Alimov; Ok-Kyong Park-Sarge; Hartmut H Malluche
Suppression of the human parathyroid hormone promoter by vitamin D involves displacement of NF-Y binding to the vitamin D response element.
The Journal of biological chemistry 2004;279(41):42431-7.
2004: Alexander P Alimov; M Chris Langub; Hartmut H Malluche; Ok-Kyong Park-Sarge; Nicholas J Koszewski
Contrasting mammalian parathyroid hormone (PTH) promoters: nuclear factor-Y binds to a deoxyribonucleic acid element unique to the human PTH promoter and acts as a transcriptional enhancer.
Endocrinology 2004;145(6):2713-20.
2003: Nicholas J Koszewski; Kenneth W Henry; Eric J Lubert; Holli Gravatte; Daniel J Noonan
Use of a modified yeast one-hybrid screen to identify BAF60a interactions with the Vitamin D receptor heterodimer.
The Journal of steroid biochemistry and molecular biology 2003;87(4-5):223-31.
2003: Nancy G Pedigo; Hongxing Zhang; Nicholas J Koszewski; David Kaetzel
A 5'-distal element mediates vitamin D-inducibility of PDGF-A gene transcription.
Growth factors (Chur, Switzerland) 2003;21(3-4):151-60.
2003: Alexander P Alimov; M Chris Langub; Hartmut H Malluche; Nicholas J Koszewski
Sp3/Sp1 in the parathyroid gland: identification of an Sp1 deoxyribonucleic acid element in the parathyroid hormone promoter.
Endocrinology 2003;144(7):3138-47.
2003: Nicholas J Koszewski; Anne Rowan
Heterodimer requirement for gene regulation by Vitamin D in variant OK cells.
Steroids 2003;68(4):307-14.
2003: M Chris Langub; Marie-Claude Monier-Faugere; Guodong Wang; John P Williams; Nicholas J Koszewski; Hartmut H Malluche
Administration of PTH-(7-84) antagonizes the effects of PTH-(1-84) on bone in rats with moderate renal failure.
Endocrinology 2003;144(4):1135-8.
2002: Hartmut H Malluche; Hanna Mawad; Nicholas J Koszewski
Update on vitamin D and its newer analogues: actions and rationale for treatment in chronic renal failure.
Kidney international 2002;62(2):367-74.
2002: Hartmut H Malluche; Marie-Claude Monier-Faugere; Nicholas J Koszewski
Use and indication of vitamin D and vitamin D analogues in patients with renal bone disease.
Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association 2002;17 Suppl 10():6-9.
2001: Nicholas J Koszewski; Stefan G Kiessling; Hartmut H Malluche
Isolation of genomic DNA sequences that bind vitamin D receptor complexes.
Biochemical and biophysical research communications 2001;283(1):188-94.
2001: M Chris Langub; Marie-Claude Monier-Faugere; Q Qi; Zhaopo Geng; Nicholas J Koszewski; Hartmut H Malluche
Parathyroid hormone/parathyroid hormone-related peptide type 1 receptor in human bone.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2001;16(3):448-56.
2001: M Chris Langub; James P Herman; Hartmut H Malluche; Nicholas J Koszewski
Evidence of functional vitamin D receptors in rat hippocampus.
Neuroscience 2001;104(1):49-56.
2000: M Chris Langub; Timothy Allen Reinhardt; Ronald L Horst; Hartmut H Malluche; Nicholas J Koszewski
Characterization of vitamin D receptor immunoreactivity in human bone cells.
Bone 2000;27(3):383-7.
2000: Nicholas J Koszewski; Hartmut H Malluche; J Russell
Vitamin D receptor interactions with positive and negative DNA response elements: an interference footprint comparison.
The Journal of steroid biochemistry and molecular biology 2000;72(3-4):125-32.
1999: J Russell; S Ashok; Nicholas J Koszewski
Vitamin D receptor interactions with the rat parathyroid hormone gene: synergistic effects between two negative vitamin D response elements.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(11):1828-37.
1999: Timothy Allen Reinhardt; Nicholas J Koszewski; J Omdahl; Ronald L Horst
1,25-Dihydroxyvitamin D(3) and 9-cis-retinoids are synergistic regulators of 24-hydroxylase activity in the rat and 1, 25-dihydroxyvitamin D(3) alters retinoic acid metabolism in vivo.
Archives of biochemistry and biophysics 1999;368(2):244-8.
1999: Nicholas J Koszewski; Timothy Allen Reinhardt; Ronald L Horst
Differential effects of 20-epi vitamin D analogs on the vitamin D receptor homodimer.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(4):509-17.
1999: Nicholas J Koszewski; S Ashok; J Russell
Turning a negative into a positive: vitamin D receptor interactions with the avian parathyroid hormone response element.
Molecular endocrinology (Baltimore, Md.) 1999;13(3):455-65.
1998: Kenneth W Henry; X Yuan; Nicholas J Koszewski; H Onda; David J Kwiatkowski; Daniel J Noonan
Tuberous sclerosis gene 2 product modulates transcription mediated by steroid hormone receptor family members.
The Journal of biological chemistry 1998;273(32):20535-9.
1998: Nicholas J Koszewski; Timothy Allen Reinhardt; M Chris Langub; Hartmut H Malluche; Ronald L Horst
Selectivity of a C-terminal peptide antiserum for different DNA-binding states of the vitamin D receptor.
Archives of biochemistry and biophysics 1998;349(2):388-96.
1997: B Peter Sawaya; Nicholas J Koszewski; Q Qi; M Chris Langub; Marie-Claude Monier-Faugere; Hartmut H Malluche
Secondary hyperparathyroidism and vitamin D receptor binding to vitamin D response elements in rats with incipient renal failure.
Journal of the American Society of Nephrology : JASN 1997;8(2):271-8.
1996: Nicholas J Koszewski; Timothy Allen Reinhardt; Ronald L Horst
Vitamin D receptor interactions with the murine osteopontin response element.
The Journal of steroid biochemistry and molecular biology 1996;59(5-6):377-88.
1996: M Chris Langub; Nicholas J Koszewski; H V Turner; Marie-Claude Monier-Faugere; Zhaopo Geng; Hartmut H Malluche
Bone resorption and mRNA expression of IL-6 and IL-6 receptor in patients with renal osteodystrophy.
Kidney international 1996;50(2):515-20.
1996: Shun Mei Liu; Nicholas J Koszewski; M Lupez; Hartmut H Malluche; A Olivera; J Russell
Characterization of a response element in the 5'-flanking region of the avian (chicken) PTH gene that mediates negative regulation of gene transcription by 1,25-dihydroxyvitamin D3 and binds the vitamin D3 receptor.
Molecular endocrinology (Baltimore, Md.) 1996;10(2):206-15.
1995: Ronald L Horst; Timothy Allen Reinhardt; J P Goff; Nicholas J Koszewski; J L Napoli
9,13-Di-cis-retinoic acid is the major circulating geometric isomer of retinoic acid in the periparturient period.
Archives of biochemistry and biophysics 1995;322(1):235-9.
1990: Nicholas J Koszewski; Timothy Allen Reinhardt; Donald C Beitz; Ronald L Horst
Developmental changes in rat kidney 1,25-dihydroxyvitamin D receptor.
Biochemical and biophysical research communications 1990;170(1):65-72.
1990: Ronald L Horst; Nicholas J Koszewski; Timothy Allen Reinhardt
1 alpha-hydroxylation of 24-hydroxyvitamin D2 represents a minor physiological pathway for the activation of vitamin D2 in mammals.
Biochemistry 1990;29(2):578-82.
1988: Nicholas J Koszewski; Timothy Allen Reinhardt; J L Napoli; Donald C Beitz; Ronald L Horst
24,26-Dihydroxyvitamin D2: a unique physiological metabolite of vitamin D2.
Biochemistry 1988;27(15):5785-90.
1987: Nicholas J Koszewski; Timothy Allen Reinhardt; Donald C Beitz; J L Napoli; E G Baggiolini; M R Uskokovic; Ronald L Horst
Use of Fourier transform 1H NMR in the identification of vitamin D2 metabolites.
Analytical biochemistry 1987;162(2):446-52.
1986: Ronald L Horst; Timothy Allen Reinhardt; C F Ramberg; Nicholas J Koszewski; J L Napoli
24-Hydroxylation of 1,25-dihydroxyergocalciferol. An unambiguous deactivation process.
The Journal of biological chemistry 1986;261(20):9250-6.