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Yashige Kotake

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Shigeru Oowada; Masashi Shimmei; Nobuyuki Endo; Hiromi Kameya; Yashige Kotake
Multiple free-radical scavenging capacity in serum.
Yoshimi Sueishi; Daisuke Yoshioka; Shigeru Oowada; Masashi Shimmei; Nobuyuki Endoh; Hirotada Fujii; Misa Ishikawa; Yashige Kotake
Oxygen radical absorbance capacity (ORAC) of cyclodextrin-solubilized flavonoids, resveratrol and astaxanthin as measured with the ORAC-EPR method.
Nobuyuki Endo; Shigeru Oowada; Yoshimi Sueishi; Masashi Shimmei; Keisuke Makino; Hirotada Fujii; Yashige Kotake
Serum hydroxyl radical scavenging capacity as quantified with iron-free hydroxyl radical source.

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All Publications

2012: Shigeru Oowada; Masashi Shimmei; Nobuyuki Endo; Hiromi Kameya; Yashige Kotake
Multiple free-radical scavenging capacity in serum.
Journal of clinical biochemistry and nutrition 2012;51(2):117-21.
2012: Yoshimi Sueishi; Daisuke Yoshioka; Shigeru Oowada; Masashi Shimmei; Nobuyuki Endoh; Hirotada Fujii; Misa Ishikawa; Yashige Kotake
Oxygen radical absorbance capacity (ORAC) of cyclodextrin-solubilized flavonoids, resveratrol and astaxanthin as measured with the ORAC-EPR method.
Journal of clinical biochemistry and nutrition 2012;50(2):127-32.
2009: Nobuyuki Endo; Shigeru Oowada; Yoshimi Sueishi; Masashi Shimmei; Keisuke Makino; Hirotada Fujii; Yashige Kotake
Serum hydroxyl radical scavenging capacity as quantified with iron-free hydroxyl radical source.
Journal of clinical biochemistry and nutrition 2009;45(2):193-201.
2009: Shunji Kohri; Hirotada Fujii; Shigeru Oowada; Nobuyuki Endoh; Yoshimi Sueishi; Miku Kusakabe; Masashi Shimmei; Yashige Kotake
An oxygen radical absorbance capacity-like assay that directly quantifies the antioxidant's scavenging capacity against AAPH-derived free radicals.
Analytical biochemistry 2009;386(2):167-71.
2008: Taketoshi Asanuma; Sabrina Doblas; Yasvir A Tesiram; Debra Saunders; Rebecca Cranford; Hironobu Yasui; Osamu Inanami; Nataliya Smith; Robert A Floyd; Yashige Kotake; Rheal A Towner
Visualization of the protective ability of a free radical trapping compound against rat C6 and F98 gliomas with diffusion tensor fiber tractography.
Journal of magnetic resonance imaging : JMRI 2008;28(3):574-87.
2007: Kaname Uno; Katsuaki Kato; Tomoaki Atsumi; Takehito Suzuki; Jun Yoshitake; Hidetoshi Morita; Shuichi Ohara; Yashige Kotake; Tooru Shimosegawa; Tetsuhiko Yoshimura
Toll-like receptor (TLR) 2 induced through TLR4 signaling initiated by Helicobacter pylori cooperatively amplifies iNOS induction in gastric epithelial cells.
American journal of physiology. Gastrointestinal and liver physiology 2007;293(5):G1004-12.
2007: Mitsuru Nonogawa; Seung Pil Pack; Toshiyuki Arai; Nobuyuki Endo; Piyanart Sommani; Tsutomu Kodaki; Yashige Kotake; Keisuke Makino
Synthesis of 6-formylpterin nucleoside analogs and their ROS generation activities in the presence of NADH in the dark.
Organic & biomolecular chemistry 2007;5(20):3314-9.
2007: Yoshiko Inoue; Taketoshi Asanuma; Nataliya Smith; Debra Saunders; Jenny Oblander; Yashige Kotake; Robert A Floyd; Rheal A Towner
Modulation of Fas-FasL related apoptosis by PBN in the early phases of choline deficient diet-mediated hepatocarcinogenesis in rats.
Free radical research 2007;41(9):972-80.
2007: Mitsuru Nonogawa; Piyanart Sommani; Toshiyuki Arai; Nobuyuki Endo; Seung Pil Pack; Tsutomu Kodaki; Yashige Kotake; Keisuke Makino
Chemical natures of 6-formylpterin nucleoside analogs.
Nucleic acids symposium series (2004) 2007;(51):227-8.
2006: Masato Kamibayashi; Shigeru Oowada; Hiroaki Kameda; Taiichi Okada; Osamu Inanami; Shunsaku Ohta; Toshihiko Ozawa; Keisuke Makino; Yashige Kotake
Synthesis and characterization of a practically better DEPMPO-type spin trap, 5-(2,2-dimethyl-1,3-propoxy cyclophosphoryl)-5-methyl-1-pyrroline N-oxide (CYPMPO).
Free radical research 2006;40(11):1166-72.
2006: Kiyoshi Asada; Rumiko Asada; Hitoshi Yoshiji; Hiroshi Fukui; Robert A Floyd; Yashige Kotake
DNA cytosine methylation profile in various cancer-related genes is altered in cultured rat hepatocyte cell lines as compared with primary hepatocytes.
Oncology reports 2006;15(5):1241-8.
2006: Yoshimi Sueishi; Daisuke Yoshioka; Chiharu Yoshioka; Shunzo Yamamoto; Yashige Kotake
High static pressure alters spin trapping rates in solution. Dependence on the structure of nitrone spin traps.
Organic & biomolecular chemistry 2006;4(5):896-901.
2006: Kiyoshi Asada; Yashige Kotake; Rumiko Asada; Deborah Saunders; Robert H Broyles; Rheal A Towner; Hiroshi Fukui; Robert A Floyd
LINE-1 hypomethylation in a choline-deficiency-induced liver cancer in rats: dependence on feeding period.
Journal of biomedicine & biotechnology 2006;2006(1):17142.
2005: Masaki Tanito; Michael H Elliott; Yashige Kotake; Robert E Anderson
Protein modifications by 4-hydroxynonenal and 4-hydroxyhexenal in light-exposed rat retina.
Investigative ophthalmology & visual science 2005;46(10):3859-68.
2005: Wei-Xing Guo; Quentin N Pye; Kelly S Williamson; Charles A Stewart; Kenneth Hensley; Yashige Kotake; Robert A Floyd; Robert H Broyles
Mitochondrial dysfunction in choline deficiency-induced apoptosis in cultured rat hepatocytes.
Free radical biology & medicine 2005;39(5):641-50.
2005: Hiroshi Tomita; Yashige Kotake; Robert E Anderson
Mechanism of protection from light-induced retinal degeneration by the synthetic antioxidant phenyl-N-tert-butylnitrone.
Investigative ophthalmology & visual science 2005;46(2):427-34.
2005: Yashige Kotake; Hideki Kishida; Dai Nakae; Robert A Floyd
Nitric oxide production by primary liver cells isolated from amino acid diet-fed rats.
Methods in enzymology 2005;396():535-41.
2004: Danny R Moore; Yashige Kotake; Mark M Huycke
Effects of iron and phytic acid on production of extracellular radicals by Enterococcus faecalis.
Experimental biology and medicine (Maywood, N.J.) 2004;229(11):1186-95.
2004: Wei-Xing Guo; Quentin N Pye; Kelly S Williamson; Charles A Stewart; Kenneth Hensley; Yashige Kotake; Robert A Floyd; Robert H Broyles
Reactive oxygen species in choline deficiency-induced apoptosis in rat hepatocytes.
Free radical biology & medicine 2004;37(7):1081-9.
2004: Tetsuhiko Yoshimura; Yashige Kotake
Spin trapping of nitric oxide with the iron-dithiocarbamate complex: chemistry and biology.
Antioxidants & redox signaling 2004;6(3):639-47.
2004: Dai Nakae; Fumiyuki Uematsu; Hideki Kishida; Osamu Kusuoka; Shin-Ichi Katsuda; Midori Yoshida; Masakazu Takahashi; Akihiko Maekawa; Ayumi Denda; Yoichi Konishi; Yashige Kotake; Robert A Floyd
Inhibition of the development of hepatocellular carcinomas by phenyl N-tert-butyl nitrone in rats fed with a choline-deficient, L-amino acid-defined diet.
Cancer letters 2004;206(1):1-13.
2003: Tahereh Tabatabaie; Angelica Vasquez-Weldon; Danny R Moore; Yashige Kotake
Free radicals and the pathogenesis of type 1 diabetes: beta-cell cytokine-mediated free radical generation via cyclooxygenase-2.
Diabetes 2003;52(8):1994-9.
2003: Isabelle Ranchon; Matthew M LaVail; Yashige Kotake; Robert E Anderson
Free radical trap phenyl-N-tert-butylnitrone protects against light damage but does not rescue P23H and S334ter rhodopsin transgenic rats from inherited retinal degeneration.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2003;23(14):6050-7.
2003: Monika Z Wrona; Xiang-Rong Jiang; Yashige Kotake; Glenn Dryhurst
Stability of the putative neurotoxin tryptamine-4,5-dione.
Chemical research in toxicology 2003;16(4):493-501.
2003: Stephen R Thom; Donald Fisher; Jie Zhang; Veena M Bhopale; S Tsuyoshi Ohnishi; Yashige Kotake; Tomoko Ohnishi; Donald G Buerk
Stimulation of perivascular nitric oxide synthesis by oxygen.
American journal of physiology. Heart and circulatory physiology 2003;284(4):H1230-9.
2003: Yashige Kotake; Danny R Moore; Angelica Vasquez-Walden; Tahereh Tabatabaie; Hong Sang
Antioxidant amplifies antibiotic protection in the cecal ligation and puncture model of microbial sepsis through interleukin-10 production.
Shock (Augusta, Ga.) 2003;19(3):252-6.
2003: Dai Nakae; Hideki Kishida; Tomonori Enami; Yoichi Konishi; Kenneth Hensley; Robert A Floyd; Yashige Kotake
Effects of phenyl N-tert-butyl nitrone and its derivatives on the early phase of hepatocarcinogenesis in rats fed a choline-deficient, L-amino acid-defined diet.
Cancer science 2003;94(1):26-31.
2002: Anat Biegon; M Alvarado; Thomas F Budinger; Rachel Grossman; Kenneth Hensley; M S West; Yashige Kotake; M Ono; Robert A Floyd
Region-selective effects of neuroinflammation and antioxidant treatment on peripheral benzodiazepine receptors and NMDA receptors in the rat brain.
Journal of neurochemistry 2002;82(4):924-34.
2002: Robert A Floyd; Yashige Kotake; Kenneth Hensley; Dai Nakae; Yoichi Konishi
Reactive oxygen species in choline deficiency induced carcinogenesis and nitrone inhibition.
Molecular and cellular biochemistry 2002;234-235(1-2):195-203.
2002: Yashige Kotake; Hong Sang; Tahereh Tabatabaie; Gemma L Wallis; Danny R Moore; Charles A Stewart
Interleukin-10 overexpression mediates phenyl-N-tert-butyl nitrone protection from endotoxemia.
Shock (Augusta, Ga.) 2002;17(3):210-6.
2002: Yuji Naito; Tomohisa Takagi; Takeshi Ishikawa; Osamu Handa; Naoyuki Matsumoto; Nobuaki Yagi; Kiichi Matsuyama; Norimasa Yoshida; Toshikazu Yoshikawa; Yashige Kotake
alpha-Phenyl-N-tert-butylnitrone provides protection from dextran sulfate sodium-induced colitis in mice.
Antioxidants & redox signaling 2002;4(1):195-206.
2001: H Endoh; N Kato; S Fujii; Y Suzuki; S Sato; T Kayama; Yashige Kotake; Tetsuhiko Yoshimura
Spin trapping agent, phenyl N-tert-butylnitrone, reduces nitric oxide production in the rat brain during experimental meningitis.
Free radical research 2001;35(5):583-91.
2001: Mark M Huycke; D Moore; W Joyce; P Wise; L Shepard; Yashige Kotake; Michael S Gilmore
Extracellular superoxide production by Enterococcus faecalis requires demethylmenaquinone and is attenuated by functional terminal quinol oxidases.
Molecular microbiology 2001;42(3):729-40.
2001: Tahereh Tabatabaie; A M Vasquez; Danny R Moore; Robert A Floyd; Yashige Kotake
Direct administration of interleukin-1 and interferon-gamma to rat pancreas leads to the in vivo production of nitric oxide and expression of inducible nitric oxide synthase and inducible cyclooxygenase.
Pancreas 2001;23(3):316-22.
2000: Tahereh Tabatabaie; A M Waldon; J M Jacob; Robert A Floyd; Yashige Kotake
COX-2 inhibition prevents insulin-dependent diabetes in low-dose streptozotocin-treated mice.
Biochemical and biophysical research communications 2000;273(2):699-704.
2000: Kenneth Hensley; Yashige Kotake; Hong Sang; Quentin N Pye; Gemma L Wallis; L M Kolker; Tahereh Tabatabaie; Charles A Stewart; Yoichi Konishi; Dai Nakae; Robert A Floyd
Dietary choline restriction causes complex I dysfunction and increased H(2)O(2) generation in liver mitochondria.
Carcinogenesis 2000;21(5):983-9.
2000: Tahereh Tabatabaie; K L Graham; A M Vasquez; Robert A Floyd; Yashige Kotake
Inhibition of the cytokine-mediated inducible nitric oxide synthase expression in rat insulinoma cells by phenyl N-tert-butylnitrone.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 2000;4(2):157-67.
2000: Lester A Reinke; Danny R Moore; Hong Sang; EG Janzen; Yashige Kotake
Aromatic hydroxylation in PBN spin trapping by hydroxyl radicals and cytochrome P-450.
Free radical biology & medicine 2000;28(3):345-50.
1999: Yashige Kotake; Hong Sang; Gemma L Wallis; Charles A Stewart
Phenyl N-tert-butylnitrone provides protection from endotoxin shock through amplified production of the anti-inflammatory cytokine interleukin-10.
Archives of biochemistry and biophysics 1999;371(1):129-31.
1999: Charles A Stewart; K Hyam; Gemma L Wallis; Hong Sang; KA Robinson; Robert A Floyd; Yashige Kotake; Kenneth Hensley
Phenyl-N-tert-butylnitrone demonstrates broad-spectrum inhibition of apoptosis-associated gene expression in endotoxin-treated rats.
Archives of biochemistry and biophysics 1999;365(1):71-4.
1999: Hong Sang; Gemma L Wallis; Charles A Stewart; Yashige Kotake
Expression of cytokines and activation of transcription factors in lipopolysaccharide-administered rats and their inhibition by phenyl N-tert-butylnitrone (PBN).
Archives of biochemistry and biophysics 1999;363(2):341-8.
1999: Yashige Kotake
Pharmacologic properties of phenyl N-tert-butylnitrone.
Antioxidants & redox signaling 1999;1(4):481-99.
1999: Yashige Kotake; Danny R Moore; Hong Sang; Lester A Reinke
Continuous monitoring of in vivo nitric oxide formation using EPR analysis in biliary flow.
Nitric oxide : biology and chemistry / official journal of the Nitric Oxide Society 1999;3(2):114-22.
1998: Yashige Kotake; Hong Sang; T Miyajima; Gemma L Wallis
Inhibition of NF-kappaB, iNOS mRNA, COX2 mRNA, and COX catalytic activity by phenyl-N-tert-butylnitrone (PBN).
Biochimica et biophysica acta 1998;1448(1):77-84.
1998: Dai Nakae; Yashige Kotake; Hideki Kishida; Kenneth Hensley; Ayumi Denda; Y Kobayashi; Wakashi Kitayama; Toshifumi Tsujiuchi; Hong Sang; Charles A Stewart; Tahereh Tabatabaie; Robert A Floyd; Yoichi Konishi
Inhibition by phenyl N-tert-butyl nitrone of early phase carcinogenesis in the livers of rats fed a choline-deficient, L-amino acid-defined diet.
Cancer research 1998;58(20):4548-51.
1998: Lester A Reinke; Yashige Kotake; Danny R Moore; Amin A Nanji
Free radical formation during ketamine anesthesia in rats: a cautionary note.
Free radical biology & medicine 1998;24(6):1002-6.
1997: Tahereh Tabatabaie; Yashige Kotake; Gemma L Wallis; J M Jacob; Robert A Floyd
Spin trapping agent phenyl N-tert-butylnitrone protects against the onset of drug-induced insulin-dependent diabetes mellitus.
FEBS letters 1997;407(2):148-52.
1997: T Miyajima; Yashige Kotake
Optimal time and dosage of phenyl N-tert-butyl nitrone (PBN) for the inhibition of nitric oxide synthase induction in mice.
Free radical biology & medicine 1997;22(3):463-70.
1996: Gemma L Wallis; Daniel J Brackett; M Lerner; Yashige Kotake; Roberto Bolli; PB McCay
In vivo spin trapping of nitric oxide generated in the small intestine, liver, and kidney during the development of endotoxemia: a time-course study.
Shock (Augusta, Ga.) 1996;6(4):274-8.
1996: E G Janzen; M S West; Yashige Kotake; C M DuBose
Biological spin trapping methodology. III. Octanol-water partition coefficients of spin-trapping compounds.
Journal of biochemical and biophysical methods 1996;32(3):183-90.
1996: E G Janzen; N Sankuratri; Yashige Kotake
Chiral spin traps. The spin trapping chemistry of 5-methyl-5-phenylpyrroline-N-oxide (MPPO).
Journal of magnetic resonance. Series B 1996;111(3):254-61.
1996: Yashige Kotake; T Tanigawa; M Tanigawa; I Ueno; D R Allen; C S Lai
Continuous monitoring of cellular nitric oxide generation by spin trapping with an iron-dithiocarbamate complex.
Biochimica et biophysica acta 1996;1289(3):362-8.
1996: Tahereh Tabatabaie; C Stewart; Quentin N Pye; Yashige Kotake; Robert A Floyd
In vivo trapping of nitric oxide in the brain of neonatal rats treated with the HIV-1 envelope protein gp 120: protective effects of alpha-phenyl-tert-butylnitrone.
Biochemical and biophysical research communications 1996;221(2):386-90.
1996: N Sankuratri; Yashige Kotake; E G Janzen
Studies on the stability of oxygen radical spin adducts of a new spin trap: 5-methyl-5-phenylpyrroline-1-oxide (MPPO).
Free radical biology & medicine 1996;21(6):889-94.
1996: Yashige Kotake
Continuous and quantitative monitoring of rate of cellular nitric oxide generation.
Methods in enzymology 1996;268():222-9.
1995: T Miyajima; Yashige Kotake
Spin trapping agent, phenyl N-tert-butyl nitrone, inhibits induction of nitric oxide synthase in endotoxin-induced shock in mice.
Biochemical and biophysical research communications 1995;215(1):114-21.
1995: Yashige Kotake; T Tanigawa; M Tanigawa; I Ueno
Spin trapping isotopically-labelled nitric oxide produced from [15N]L-arginine and [17O]dioxygen by activated macrophages using a water soluble Fe(++)-dithiocarbamate spin trap.
Free radical research 1995;23(3):287-95.
1995: L Seawright; M Tanigawa; T Tanigawa; Yashige Kotake; E G Janzen
Can spin trapping compounds like PBN protect against self-inflicted damage in polymorphonuclear leukocytes?
Free radical research 1995;23(1):73-80.
1995: T Tanigawa; Yashige Kotake; M Tanigawa; Lester A Reinke
Mutual contact of adherent polymorphonuclear leukocytes inhibits their generation of superoxide.
Free radical research 1995;22(4):361-73.
1994: Yashige Kotake; Lester A Reinke; T Tanigawa; H Koshida
Determination of the rate of superoxide generation from biological systems by spin trapping: use of rapid oxygen depletion to measure the decay rate of spin adducts.
Free radical biology & medicine 1994;17(3):215-23.
1994: H Koshida; Yashige Kotake
Corticotropin-releasing hormone enhances the superoxide anion production of rabbit peritoneal macrophages stimulated with N-formyl-methionyl-leucyl-phenylalanine.
Life sciences 1994;54(8):539-43.
1994: H Koshida; Yashige Kotake
Nitric oxide does not contribute to superoxide-mediated sulfhydryl oxidation in human polymorphonuclear leukocytes.
Life sciences 1994;55(6):463-70.
1993: T Tanigawa; Yashige Kotake; Lester A Reinke
Spin trapping of superoxide radicals following stimulation of neutrophils with fMLP is temperature dependent.
Free radical biology & medicine 1993;15(4):425-33.
1993: H Koshida; Yashige Kotake
Thyrotropin-releasing hormone enhances the superoxide anion production of rabbit peritoneal macrophages stimulated with N-formyl-methionyl-leucyl-phenylalanine and opsonized zymosan.
Life sciences 1993;53(9):725-31.
1993: T Tanigawa; Yashige Kotake; Lester A Reinke
Spin trapping of superoxide from glass adherent polymorphonuclear leukocytes induced by N-formylmethionyl-leucyl-phenylalanine.
Free radical research communications 1993;19(2):101-10.
1992: E G Janzen; Yashige Kotake; R D Hinton
Stabilities of hydroxyl radical spin adducts of PBN-type spin traps.
Free radical biology & medicine 1992;12(2):169-73.