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Thomas Kozel

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

Research Profile (preview)

Living Beings

Chemicals & Drugs

Physiology

Disorders

Cryptococcosis

Concepts & Ideas

Kinetics

Anatomy

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Co-Publications
Name
20
Vecchiarelli, Anna
18
Monari, Claudia
14
Casadevall, Arturo
13
Bistoni, Francesco
10
Pietrella, Donatella
10
Thorkildson, Peter
10
Retini, Cinzia
8
MacGill, Randall
7
Zhang, Mason
4
Pericolini, Eva
4
Netski, Dale
4
Gates, Marcellene
3
Cutler, Jim
3
Brandt, Suzanne
3
Palazzetti, B

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Publications

TOP 3
Gates-Hollingsworth Marcellene A; Kozel Thomas R
Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule.
Monari Claudia; Bevilacqua Sara; Piccioni Miranda; Pericolini Eva; Perito Stefano; Calvitti Mario; Bistoni Francesco; Kozel Thomas R; Vecchiarelli Anna
A microbial polysaccharide reduces the severity of rheumatoid arthritis by influencing Th17 differentiation and proinflammatory cytokines production.
AuCoin David P; Sutherland Marjorie D; Percival Ann L; Lyons C Rick; Lovchik Julie A; Kozel Thomas R
Rapid detection of the poly-gamma-D-glutamic acid capsular antigen of Bacillus anthracis by latex agglutination.

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All Publications

2009: Gates-Hollingsworth Marcellene A; Kozel Thomas R
Phenotypic heterogeneity in expression of epitopes in the Cryptococcus neoformans capsule.
Molecular microbiology 2009;74(1):126-38.
2009: Monari Claudia; Bevilacqua Sara; Piccioni Miranda; Pericolini Eva; Perito Stefano; Calvitti Mario; Bistoni Francesco; Kozel Thomas R; Vecchiarelli Anna
A microbial polysaccharide reduces the severity of rheumatoid arthritis by influencing Th17 differentiation and proinflammatory cytokines production.
Journal of immunology (Baltimore, Md. : 1950) 2009;183(1):191-200.
2009: AuCoin David P; Sutherland Marjorie D; Percival Ann L; Lyons C Rick; Lovchik Julie A; Kozel Thomas R
Rapid detection of the poly-gamma-D-glutamic acid capsular antigen of Bacillus anthracis by latex agglutination.
Diagnostic microbiology and infectious disease 2009;64(2):229-32.
2009: Tian Haijun; Weber Sarah; Thorkildson Peter; Kozel Thomas R; Pirofski Liise-Anne
Efficacy of opsonic and nonopsonic serotype 3 pneumococcal capsular polysaccharide-specific monoclonal antibodies against intranasal challenge with Streptococcus pneumoniae in mice.
Infection and immunity 2009;77(4):1502-13.
2009: Boxx Gayle M; Nishiya Casey T; Kozel Thomas R; Zhang Mason X
Characteristics of Fc-independent human antimannan antibody-mediated alternative pathway initiation of C3 deposition to Candida albicans.
Molecular immunology 2009;46(3):473-80.
2008: Monari Claudia; Paganelli Francesca; Bistoni Francesco; Kozel Thomas R; Vecchiarelli Anna
Capsular polysaccharide induction of apoptosis by intrinsic and extrinsic mechanisms.
Cellular microbiology 2008;10(10):2129-37.
2008: Sutherland Marjorie D; Thorkildson Peter; Parks Samuel D; Kozel Thomas R
In vivo fate and distribution of poly-gamma-D-glutamic acid, the capsular antigen from Bacillus anthracis.
Infection and immunity 2008;76(3):899-906.
2007: Zhou Qing; Gault Ruth A; Kozel Thomas R; Murphy William J
Protection from direct cerebral cryptococcus infection by interferon-gamma-dependent activation of microglial cells.
Journal of immunology (Baltimore, Md. : 1950) 2007;178(9):5753-61.
2007: Kozel Thomas R; Thorkildson Peter; Brandt Suzanne; Welch William H; Lovchik Julie A; AuCoin David P; Vilai Julpohng; Lyons C Rick
Protective and immunochemical activities of monoclonal antibodies reactive with the Bacillus anthracis polypeptide capsule.
Infection and immunity 2007;75(1):152-63.
2006: Monari Claudia; Kozel Thomas R; Paganelli Francesca; Pericolini Eva; Perito Stefano; Bistoni Francesco; Casadevall Arturo; Vecchiarelli Anna
Microbial immune suppression mediated by direct engagement of inhibitory Fc receptor.
Journal of immunology (Baltimore, Md. : 1950) 2006;177(10):6842-51.
2006: Gates Marcellene A; Kozel Thomas R
Differential localization of complement component 3 within the capsular matrix of Cryptococcus neoformans.
Infection and immunity 2006;74(6):3096-106.
2006: Lillegard Joseph B; Sim Robert B; Thorkildson Peter; Gates Marcellene A; Kozel Thomas R
Recognition of Candida albicans by mannan-binding lectin in vitro and in vivo.
The Journal of infectious diseases 2006;193(11):1589-97.
2006: Zhou Qing; Gault Ruth A; Kozel Thomas R; Murphy William J
Immunomodulation with CD40 stimulation and interleukin-2 protects mice from disseminated cryptococcosis.
Infection and immunity 2006;74(4):2161-8.
2006: Zhang Mason X; Bohlman M Charlotte; Itatani Carol; Burton Dennis R; Parren Paul W H I; St Jeor Stephen C; Kozel Thomas R
Human recombinant antimannan immunoglobulin G1 antibody confers resistance to hematogenously disseminated candidiasis in mice.
Infection and immunity 2006;74(1):362-9.
2006: Chang Zong Liang; Netski Dale; Thorkildson Peter; Kozel Thomas R
Binding and internalization of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, by murine peritoneal macrophages.
Infection and immunity 2006;74(1):144-51.
2005: Monari Claudia; Pericolini Eva; Bistoni Giovanni; Casadevall Arturo; Kozel Thomas R; Vecchiarelli Anna
Cryptococcus neoformans capsular glucuronoxylomannan induces expression of fas ligand in macrophages.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(6):3461-8.
2005: Monari Claudia; Bistoni Francesco; Casadevall Arturo; Pericolini Eva; Pietrella Donatella; Kozel Thomas R; Vecchiarelli Anna
Glucuronoxylomannan, a microbial compound, regulates expression of costimulatory molecules and production of cytokines in macrophages.
The Journal of infectious diseases 2005;191(1):127-37.
2005: Deyde Varough; Rizvanov Albert; Otteson Elmer; Brandt Suzanne; Bego Mariana; Pari Gregory; Kozel Thomas; St Jeor Stephen
Identification of a monoclonal antibody from Peromyscus maniculatus (deer mouse) cytomegalovirus (PCMV) which binds to a protein with homology to the human CMV matrix protein HCMV pp71.
Journal of virological methods 2005;123(1):9-15.
2004: Tissi Luciana; Puliti Manuela; Bistoni Francesco; Mosci Paolo; Kozel Thomas R; Vecchiarelli Anna
Glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans, inhibits the progression of group B streptococcal arthritis.
Infection and immunity 2004;72(11):6367-72.
2004: Kozel Thomas R; Murphy William J; Brandt Suzanne; Blazar Bruce R; Lovchik Julie A; Thorkildson Peter; Percival Ann; Lyons C Rick
mAbs to Bacillus anthracis capsular antigen for immunoprotection in anthrax and detection of antigenemia.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(14):5042-7.
2004: Gates Marcellene A; Thorkildson Peter; Kozel Thomas R
Molecular architecture of the Cryptococcus neoformans capsule.
Molecular microbiology 2004;52(1):13-24.
2004: Kozel Thomas R; MacGill Randall S; Percival Ann; Zhou Qing
Biological activities of naturally occurring antibodies reactive with Candida albicans mannan.
Infection and immunity 2004;72(1):209-18.
2003: Brandt Suzanne; Thorkildson Peter; Kozel Thomas R
Monoclonal antibodies reactive with immunorecessive epitopes of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans.
Clinical and diagnostic laboratory immunology 2003;10(5):903-9.
2003: Kozel Thomas R; Levitz Stuart M; Dromer Françoise; Gates Marcellene A; Thorkildson Peter; Janbon Guilhem
Antigenic and biological characteristics of mutant strains of Cryptococcus neoformans lacking capsular O acetylation or xylosyl side chains.
Infection and immunity 2003;71(5):2868-75.
2003: Monari Claudia; Retini Cinzia; Casadevall Arturo; Netski Dale; Bistoni Francesco; Kozel Thomas R; Vecchiarelli Anna
Differences in outcome of the interaction between Cryptococcus neoformans glucuronoxylomannan and human monocytes and neutrophils.
European journal of immunology 2003;33(4):1041-51.
2003: Duro Raymond M; Netski Dale; Thorkildson Peter; Kozel Thomas R
Contribution of epitope specificity to the binding of monoclonal antibodies to the capsule of Cryptococcus neoformans and the soluble form of its major polysaccharide, glucuronoxylomannan.
Clinical and diagnostic laboratory immunology 2003;10(2):252-8.
2002: Monari Claudia; Kozel Thomas R; Bistoni Francesco; Vecchiarelli Anna
Modulation of C5aR expression on human neutrophils by encapsulated and acapsular Cryptococcus neoformans.
Infection and immunity 2002;70(7):3363-70.
2002: Vecchiarelli Anna; Pietrella Donatella; Bistoni Francesco; Kozel Thomas R; Casadevall Arturo
Antibody to Cryptococcus neoformans capsular glucuronoxylomannan promotes expression of interleukin-12Rbeta2 subunit on human T cells in vitro through effects mediated by antigen-presenting cells.
Immunology 2002;106(2):267-72.
2002: Netski Dale; Kozel Thomas R
Fc-dependent and Fc-independent opsonization of Cryptococcus neoformans by anticapsular monoclonal antibodies: importance of epitope specificity.
Infection and immunity 2002;70(6):2812-9.
2002: Rosas A L; MacGill R S; Nosanchuk J D; Kozel T R; Casadevall A
Activation of the alternative complement pathway by fungal melanins.
Clinical and diagnostic laboratory immunology 2002;9(1):144-8.
2001: Zhang M X; Brandhorst T T; Kozel T R; Klein B S
Role of glucan and surface protein BAD1 in complement activation by Blastomyces dermatitidis yeast.
Infection and immunity 2001;69(12):7559-64.
2001: Retini C; Kozel T R; Pietrella D; Monari C; Bistoni F; Vecchiarelli A
Interdependency of interleukin-10 and interleukin-12 in regulation of T-cell differentiation and effector function of monocytes in response to stimulation with Cryptococcus neoformans.
Infection and immunity 2001;69(10):6064-73.
2001: Grinsell M; Weinhold L C; Cutler J E; Han Y; Kozel T R
In vivo clearance of glucuronoxylomannan, the major capsular polysaccharide of Cryptococcus neoformans: a critical role for tissue macrophages.
The Journal of infectious diseases 2001;184(4):479-87.
2001: Han Y; Kozel T R; Zhang M X; MacGill R S; Carroll M C; Cutler J E
Complement is essential for protection by an IgM and an IgG3 monoclonal antibody against experimental, hematogenously disseminated candidiasis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1550-7.
2001: MacGill T C; MacGill R S; Kozel T R
Capsular reactions of Cryptococcus neoformans with polyspecific and oligospecific polyclonal anticapsular antibodies.
Infection and immunity 2001;69(2):1189-91.
2001: Pietrella D; Kozel T R; Monari C; Bistoni F; Vecchiarelli A
Interleukin-12 counterbalances the deleterious effect of human immunodeficiency virus type 1 envelope glycoprotein gp120 on the immune response to Cryptococcus neoformans.
The Journal of infectious diseases 2001;183(1):51-8.
2000: Feldmesser M; Rivera J; Kress Y; Kozel T R; Casadevall A
Antibody interactions with the capsule of Cryptococcus neoformans.
Infection and immunity 2000;68(6):3642-50.
2000: Vecchiarelli A; Retini C; Pietrella D; Monari C; Kozel T R
T lymphocyte and monocyte interaction by CD40/CD40 ligand facilitates a lymphoproliferative response and killing of Cryptococcus neoformans in vitro.
European journal of immunology 2000;30(5):1385-93.
2000: MacGill T C; MacGill R S; Casadevall A; Kozel T R
Biological correlates of capsular (quellung) reactions of Cryptococcus neoformans.
Journal of immunology (Baltimore, Md. : 1950) 2000;164(9):4835-42.
1999: Pietrella D; Monari C; Retini C; Palazzetti B; Kozel T R; Vecchiarelli A
HIV type 1 envelope glycoprotein gp120 induces development of a T helper type 2 response to Cryptococcus neoformans.
AIDS (London, England) 1999;13(16):2197-207.
1999: Monari C; Kozel T R; Casadevall A; Pietrella D; Palazzetti B; Vecchiarelli A
B7 costimulatory ligand regulates development of the T-cell response to Cryptococcus neoformans.
Immunology 1999;98(1):27-35.
1998: Zhang M X; Cutler J E; Han Y; Kozel T R
Contrasting roles of mannan-specific monoclonal immunoglobulin M antibodies in the activation of classical and alternative pathways by Candida albicans.
Infection and immunity 1998;66(12):6027-9.
1998: Pietrella D; Monari C; Retini C; Palazzetti B; Kozel T R; Vecchiarelli A
Cryptococcus neoformans and Candida albicans regulate CD4 expression on human monocytes.
The Journal of infectious diseases 1998;178(5):1464-71.
1998: Mukherjee J; Kozel T R; Casadevall A
Monoclonal antibodies reveal additional epitopes of serotype D Cryptococcus neoformans capsular glucuronoxylomannan that elicit protective antibodies.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(7):3557-68.
1998: Zhang M X; Kozel T R
Mannan-specific immunoglobulin G antibodies in normal human serum accelerate binding of C3 to Candida albicans via the alternative complement pathway.
Infection and immunity 1998;66(10):4845-50.
1998: Vecchiarelli A; Retini C; Casadevall A; Monari C; Pietrella D; Kozel T R
Involvement of C3a and C5a in interleukin-8 secretion by human polymorphonuclear cells in response to capsular material of Cryptococcus neoformans.
Infection and immunity 1998;66(9):4324-30.
1998: Casadevall A; Cleare W; Feldmesser M; Glatman-Freedman A; Goldman D L; Kozel T R; Lendvai N; Mukherjee J; Pirofski L A; Rivera J; Rosas A L; Scharff M D; Valadon P; Westin K; Zhong Z
Characterization of a murine monoclonal antibody to Cryptococcus neoformans polysaccharide that is a candidate for human therapeutic studies.
Antimicrobial agents and chemotherapy 1998;42(6):1437-46.
1998: Kozel T R
Complement activation by pathogenic fungi.
Research in immunology 1998;149(4-5):309-20; discussion 514-5.
1998: Kozel T R; MacGill R S; Wall K K
Bivalency is required for anticapsular monoclonal antibodies to optimally suppress activation of the alternative complement pathway by the Cryptococcus neoformans capsule.
Infection and immunity 1998;66(4):1547-53.
1998: Kozel T R; deJong B C; Grinsell M M; MacGill R S; Wall K K
Characterization of anticapsular monoclonal antibodies that regulate activation of the complement system by the Cryptococcus neoformans capsule.
Infection and immunity 1998;66(4):1538-46.
1998: Retini C; Vecchiarelli A; Monari C; Bistoni F; Kozel T R
Encapsulation of Cryptococcus neoformans with glucuronoxylomannan inhibits the antigen-presenting capacity of monocytes.
Infection and immunity 1998;66(2):664-9.
1997: Zhang M X; Lupan D M; Kozel T R
Mannan-specific immunoglobulin G antibodies in normal human serum mediate classical pathway initiation of C3 binding to Candida albicans.
Infection and immunity 1997;65(9):3822-7.
1997: Savoy A C; Lupan D M; Manalo P B; Roberts J S; Schlageter A M; Weinhold L C; Kozel T R
Acute lethal toxicity following passive immunization for treatment of murine cryptococcosis.
Infection and immunity 1997;65(5):1800-7.
1997: Chang Y C; Cherniak R; Kozel T R; Granger D L; Morris L C; Weinhold L C; Kwon-Chung K J
Structure and biological activities of acapsular Cryptococcus neoformans 602 complemented with the CAP64 gene.
Infection and immunity 1997;65(5):1584-92.
1997: Levitz S M; Tabuni A; Kozel T R; MacGill R S; Ingalls R R; Golenbock D T
Binding of Cryptococcus neoformans to heterologously expressed human complement receptors.
Infection and immunity 1997;65(3):931-5.
1997: Belay T; Cherniak R; Kozel T R; Casadevall A
Reactivity patterns and epitope specificities of anti-Cryptococcus neoformans monoclonal antibodies by enzyme-linked immunosorbent assay and dot enzyme assay.
Infection and immunity 1997;65(2):718-28.
1996: Kozel T R; Weinhold L C; Lupan D M
Distinct characteristics of initiation of the classical and alternative complement pathways by Candida albicans.
Infection and immunity 1996;64(8):3360-8.
1996: Retini C; Vecchiarelli A; Monari C; Tascini C; Bistoni F; Kozel T R
Capsular polysaccharide of Cryptococcus neoformans induces proinflammatory cytokine release by human neutrophils.
Infection and immunity 1996;64(8):2897-903.
1996: Vecchiarelli A; Retini C; Monari C; Tascini C; Bistoni F; Kozel T R
Purified capsular polysaccharide of Cryptococcus neoformans induces interleukin-10 secretion by human monocytes.
Infection and immunity 1996;64(7):2846-9.
1996: Kozel T R; Tabuni A; Young B J; Levitz S M
Influence of opsonization conditions on C3 deposition and phagocyte binding of large- and small-capsule Cryptococcus neoformans cells.
Infection and immunity 1996;64(6):2336-8.
1996: Kozel T R
Activation of the complement system by pathogenic fungi.
Clinical microbiology reviews 1996;9(1):34-46.
1995: Kozel T R
Virulence factors of Cryptococcus neoformans.
Trends in microbiology 1995;3(8):295-9.
1995: Vecchiarelli A; Retini C; Pietrella D; Monari C; Tascini C; Beccari T; Kozel T R
Downregulation by cryptococcal polysaccharide of tumor necrosis factor alpha and interleukin-1 beta secretion from human monocytes.
Infection and immunity 1995;63(8):2919-23.
1994: Casadevall A; DeShaw M; Fan M; Dromer F; Kozel T R; Pirofski L A
Molecular and idiotypic analysis of antibodies to Cryptococcus neoformans glucuronoxylomannan.
Infection and immunity 1994;62(9):3864-72.
1994: Houpt D C; Pfrommer G S; Young B J; Larson T A; Kozel T R
Occurrences, immunoglobulin classes, and biological activities of antibodies in normal human serum that are reactive with Cryptococcus neoformans glucuronoxylomannan.
Infection and immunity 1994;62(7):2857-64.
1994: Otteson E W; Welch W H; Kozel T R
Protein-polysaccharide interactions. A monoclonal antibody specific for the capsular polysaccharide of Cryptococcus neoformans.
The Journal of biological chemistry 1994;269(3):1858-64.
1994: Keller R G; Pfrommer G S; Kozel T R
Occurrences, specificities, and functions of ubiquitous antibodies in human serum that are reactive with the Cryptococcus neoformans cell wall.
Infection and immunity 1994;62(1):215-20.
1993: Pfrommer G S; Dickens S M; Wilson M A; Young B J; Kozel T R
Accelerated decay of C3b to iC3b when C3b is bound to the Cryptococcus neoformans capsule.
Infection and immunity 1993;61(10):4360-6.
1993: Young B J; Kozel T R
Effects of strain variation, serotype, and structural modification on kinetics for activation and binding of C3 to Cryptococcus neoformans.
Infection and immunity 1993;61(7):2966-72.
1993: Kozel T R
Opsonization and phagocytosis of Cryptococcus neoformans.
Archives of medical research 1993;24(3):211-8.
1993: Kozel T R
Activation of the complement system by the capsule of Cryptococcus neoformans.
Current topics in medical mycology 1993;5():1-26.
1992: Truelsen K; Young T; Kozel T R
In vivo complement activation and binding of C3 to encapsulated Cryptococcus neoformans.
Infection and immunity 1992;60(9):3937-9.
1992: Kozel T R; Wilson M A; Welch W H
Kinetic analysis of the amplification phase for activation and binding of C3 to encapsulated and nonencapsulated Cryptococcus neoformans.
Infection and immunity 1992;60(8):3122-7.
1992: Wilson M A; Kozel T R
Contribution of antibody in normal human serum to early deposition of C3 onto encapsulated and nonencapsulated Cryptococcus neoformans.
Infection and immunity 1992;60(3):754-61.
1992: Kwon-Chung K J; Kozel T R; Edman J C; Polacheck I; Ellis D; Shinoda T; Dromer F
Recent advances in biology and immunology of Cryptococcus neoformans.
Journal of medical and veterinary mycology : bi-monthly publication of the International Society for Human and Animal Mycology 1992;30 Suppl 1():133-42.
1991: Kozel T R; Wilson M A; Murphy J W
Early events in initiation of alternative complement pathway activation by the capsule of Cryptococcus neoformans.
Infection and immunity 1991;59(9):3101-10.
1990: Sanford J E; Lupan D M; Schlageter A M; Kozel T R
Passive immunization against Cryptococcus neoformans with an isotype-switch family of monoclonal antibodies reactive with cryptococcal polysaccharide.
Infection and immunity 1990;58(6):1919-23.
1990: Schlageter A M; Kozel T R
Opsonization of Cryptococcus neoformans by a family of isotype-switch variant antibodies specific for the capsular polysaccharide.
Infection and immunity 1990;58(6):1914-8.
1989: Kozel T R; Wilson M A; Farrell T P; Levitz S M
Activation of C3 and binding to Aspergillus fumigatus conidia and hyphae.
Infection and immunity 1989;57(11):3412-7.
1989: Spiropulu C; Eppard R A; Otteson E; Kozel T R
Antigenic variation within serotypes of Cryptococcus neoformans detected by monoclonal antibodies specific for the capsular polysaccharide.
Infection and immunity 1989;57(10):3240-2.
1989: Kozel T R; Wilson M A; Pfrommer G S; Schlageter A M
Activation and binding of opsonic fragments of C3 on encapsulated Cryptococcus neoformans by using an alternative complement pathway reconstituted from six isolated proteins.
Infection and immunity 1989;57(7):1922-7.
1988: Kozel T R; Pfrommer G S; Guerlain A S; Highison B A; Highison G J
Strain variation in phagocytosis of Cryptococcus neoformans: dissociation of susceptibility to phagocytosis from activation and binding of opsonic fragments of C3.
Infection and immunity 1988;56(11):2794-800.
1988: Kozel T R; Pfrommer G S; Guerlain A S; Highison B A; Highison G J
Role of the capsule in phagocytosis of Cryptococcus neoformans.
Reviews of infectious diseases 1988;10 Suppl 2():S436-9.
1988: Kozel T R; Hermerath C A
Benzoquinone activation of Cryptococcus neoformans capsular polysaccharide for construction of an immunoaffinity column.
Journal of immunological methods 1988;107(1):53-8.
1987: Kozel T R; Pfrommer G S; Redelman D
Activated neutrophils exhibit enhanced phagocytosis of Cryptococcus neoformans opsonized with normal human serum.
Clinical and experimental immunology 1987;70(1):238-46.
1987: Kozel T R; Brown R R; Pfrommer G S
Activation and binding of C3 by Candida albicans.
Infection and immunity 1987;55(8):1890-4.
1986: Kozel T R; Pfrommer G S
Activation of the complement system by Cryptococcus neoformans leads to binding of iC3b to the yeast.
Infection and immunity 1986;52(1):1-5.
1984: Kozel T R; Hermerath C A
Binding of cryptococcal polysaccharide to Cryptococcus neoformans.
Infection and immunity 1984;43(3):879-86.

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