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T Kozu

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T Fukuyama; Eisaburo Sueoka; Yasuhiro Sugio; T Otsuka; Y Niho; K Akagi; T Kozu
MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes.
M Maeda; T Otsuka; N Kimura; T Kozu; T Fukuyama; N Uchida; Yasuhiro Sugio; Y Itoh; T Iino; S Inaba; Y Niho
Induction of MTG8-specific cytotoxic T-cell lines: MTG8 is probably a tumour antigen that is recognized by cytotoxic T cells in AML1-MTG8-fused gene-positive acute myelogenous leukaemia.
T Kozu; Yasuhiro Sugio; T Fukuyama; Eisaburo Sueoka; T Otsuka; K Akagi
Ribonuclease H attack of leukaemic fused transcripts AML1-MTG8 (ETO) by DNA/RNA chimeric hammerhead ribozymes.

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All Publications

2001: T Fukuyama; Eisaburo Sueoka; Yasuhiro Sugio; T Otsuka; Y Niho; K Akagi; T Kozu
MTG8 proto-oncoprotein interacts with the regulatory subunit of type II cyclic AMP-dependent protein kinase in lymphocytes.
Oncogene 2001;20(43):6225-32.
2000: M Maeda; T Otsuka; N Kimura; T Kozu; T Fukuyama; N Uchida; Yasuhiro Sugio; Y Itoh; T Iino; S Inaba; Y Niho
Induction of MTG8-specific cytotoxic T-cell lines: MTG8 is probably a tumour antigen that is recognized by cytotoxic T cells in AML1-MTG8-fused gene-positive acute myelogenous leukaemia.
British journal of haematology 2000;111(2):570-9.
2000: T Kozu; Yasuhiro Sugio; T Fukuyama; Eisaburo Sueoka; T Otsuka; K Akagi
Ribonuclease H attack of leukaemic fused transcripts AML1-MTG8 (ETO) by DNA/RNA chimeric hammerhead ribozymes.
Genes to cells : devoted to molecular & cellular mechanisms 2000;5(8):637-47.
1999: Eisaburo Sueoka; Y Goto; Naoko Sueoka; Y Kai; T Kozu; Hirota Fujiki
Heterogeneous nuclear ribonucleoprotein B1 as a new marker of early detection for human lung cancers.
Cancer research 1999;59(7):1404-7.
1999: A Komori; Eisaburo Sueoka; Hirota Fujiki; M Ishii; T Kozu
Association of MTG8 (ETO/CDR), a leukemia-related protein, with serine/threonine protein kinases and heat shock protein HSP90 in human hematopoietic cell lines.
Japanese journal of cancer research : Gann 1999;90(1):60-8.
1998: Hirota Fujiki; Masami Suganuma; S Okabe; Naoko Sueoka; A Komori; Eisaburo Sueoka; T Kozu; Y Tada; K Suga; K Imai; K Nakachi
Cancer inhibition by green tea.
Mutation research 1998;402(1-2):307-10.
1998: Eisaburo Sueoka; Naoko Sueoka; S Okabe; A Komori; M Suganuma; T Kozu; H Fujiki
Tumourigenicity of MTG8, a leukaemia-related gene, in concert with v-Ha-ras gene in BALB/3T3 cells.
British journal of haematology 1998;101(4):737-42.
1997: T Kozu; A Komori; Eisaburo Sueoka; H Fujiki; Y Kaneko; T Matsui; T Uehara; Y Seino; M Ishii
Significance of MTG8 in leukemogenesis.
Leukemia 1997;11 Suppl 3():297-8.
1997: Eisaburo Sueoka; Naoko Sueoka; S Okabe; T Kozu; A Komori; T Ohta; Masami Suganuma; S J Kim; In Kyoung Lim; Hirota Fujiki
Expression of the tumor necrosis factor alpha gene and early response genes by nodularin, a liver tumor promoter, in primary cultured rat hepatocytes.
Journal of cancer research and clinical oncology 1997;123(8):413-9.
1996: Hirota Fujiki; Masami Suganuma; S Okabe; A Komori; Eisaburo Sueoka; Naoko Sueoka; T Kozu; Y Sakai
Japanese green tea as a cancer preventive in humans.
Nutrition reviews 1996;54(11 Pt 2):S67-70.
1996: T Kozu; Eisaburo Sueoka; S Okabe; Naoko Sueoka; A Komori; Hirota Fujiki
In vitro catalytic activities of DNA/RNA chimeric hammerhead ribozymes against AML1-MTG8 mRNA, a fused gene transcript in acute myeloid leukemia with t(8;21).
Biochimie 1996;78(11-12):1067-73.
1996: T Kozu; Eisaburo Sueoka; S Okabe; Naoko Sueoka; A Komori; Hirota Fujiki
Designing of chimeric DNA/RNA hammerhead ribozymes to be targeted against AML1/MTG8 mRNA.
Journal of cancer research and clinical oncology 1996;122(4):254-6.
1995: T Kozu; B Henrich; K P Schäfer
Structure and expression of the gene (HNRPA2B1) encoding the human hnRNP protein A2/B1.
Genomics 1995;25(2):365-71.
1993: T Kozu; H Miyoshi; K Shimizu; N Maseki; Y Kaneko; H Asou; N Kamada; M Ohki
Junctions of the AML1/MTG8(ETO) fusion are constant in t(8;21) acute myeloid leukemia detected by reverse transcription polymerase chain reaction.
Blood 1993;82(4):1270-6.
1993: H Miyoshi; T Kozu; K Shimizu; K Enomoto; N Maseki; Y Kaneko; N Kamada; M Ohki
The t(8;21) translocation in acute myeloid leukemia results in production of an AML1-MTG8 fusion transcript.
The EMBO journal 1993;12(7):2715-21.
1992: K Shimizu; H Miyoshi; T Kozu; J Nagata; K Enomoto; N Maseki; Y Kaneko; M Ohki
Consistent disruption of the AML1 gene occurs within a single intron in the t(8;21) chromosomal translocation.
Cancer research 1992;52(24):6945-8.
1991: H Miyoshi; K Shimizu; T Kozu; N Maseki; Y Kaneko; M Ohki
t(8;21) breakpoints on chromosome 21 in acute myeloid leukemia are clustered within a limited region of a single gene, AML1.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(23):10431-4.
1990: T Kozu; K Nikaido; T Yagura
Structure of DNA polymerase alpha-primase complexes from mammalian cells analyzed by using monoclonal antibodies.
Journal of biochemistry 1990;107(4):535-8.
1987: T Yagura; T Kozu; T Seno; S Tanaka
Immunochemical detection of a primase activity related subunit of DNA polymerase alpha from human and mouse cells using the monoclonal antibody.
Biochemistry 1987;26(24):7749-54.
1986: T Kozu; T Seno; T Yagura
Activity levels of mouse DNA polymerase alpha-primase complex (DNA replicase) and DNA polymerase alpha, free from primase activity in synchronized cells, and a comparison of their catalytic properties.
European journal of biochemistry / FEBS 1986;157(2):251-9.
1986: T Yagura; T Kozu; T Seno
Size difference in catalytic polypeptides of two active forms of mouse DNA polymerase alpha and separation of the primase subunit from one form, DNA replicase.
Biochimica et biophysica acta 1986;870(1):1-11.
1983: T Yagura; T Kozu; T Seno; M Saneyoshi; S Hiraga; H Nagano
Novel form of DNA polymerase alpha associated with DNA primase activity of vertebrates. Detection with mouse stimulating factor.
The Journal of biological chemistry 1983;258(21):13070-5.
1983: T Kozu; T Yagura; T Seno
Size maturation process of nascent DNA intermediates into chromosomal-sized DNA in Tetrahymena pyriformis macronuclear DNA replication.
Experimental cell research 1983;149(1):189-200.
1983: T Yagura; T Kozu; T Seno
Mechanism of stimulation by a specific protein factor of de novo DNA synthesis by mouse DNA replicase with fd phage single stranded circular DNA.
Nucleic acids research 1983;11(18):6369-80.
1983: T Yagura; S Tanaka; T Kozu; T Seno; D Korn
Tight association of DNA primase with a subspecies of mouse DNA polymerase alpha.
The Journal of biological chemistry 1983;258(11):6698-700.
1982: T Yagura; T Kozu; T Seno
Mouse DNA replicase. DNA polymerase associated with a novel RNA polymerase activity to synthesize initiator RNA of strict size.
The Journal of biological chemistry 1982;257(18):11121-7.
1982: T Kozu; T Yagura; T Seno
De novo DNA synthesis by a novel mouse DNA polymerase associated with primase activity.
Nature 1982;298(5870):180-2.
1982: T Yagura; T Kozu; T Seno
Arrest of chain growth of replicon-sized intermediates by aphidicolin during rat fibroblast cell chromosome replication.
European journal of biochemistry / FEBS 1982;123(1):15-21.
1982: T Yagura; T Kozu; I Seno; T Nishijima; E Ohtsuka; M Ikehara
Inhibition of a novel subspecies of DNA polymerase alpha by 2'-deoxy-2'-azidoadenosine 5'-triphosphate.
Biochemical and biophysical research communications 1982;104(4):1189-95.
1982: T Yagura; T Kozu; T Seno
Mouse DNA polymerase accompanied by a novel RNA polymerase activity: purification and partial characterization.
Journal of biochemistry 1982;91(2):607-18.
1981: T Yagura; T Kozu; T Seno
Inhibition of DNA polymerases alpha and gamma by rifamycin derivative AF/013.
Journal of biochemistry 1981;90(5):1397-403.
1980: T Yagura; T Kozu; T Seno
Partial purification and characterization of poly(dC)-dependent DNA polymerase and its stimulating factor.
Biochemical and biophysical research communications 1980;92(4):1289-96.