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Evangelia Kranias
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23
Chu, Guoxiang
22
Dorn, Gerald
20
Hoit, Brian
19
Kadambi, Vivek
19
Fan, Guo-Chang
19
Schmidt, Albrecht
18
Édes, István Ferenc
15
Grupp, Ingrid
14
Haghighi, Kobra
12
Harrer, Judy
12
Ferguson, DG
12
Bers, Donald
11
Yatani, Atsuko
11
Zhao, Wen
11
Sato, Yoji
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All Publications
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2009: Papalouka Vasiliki; Arvanitis Demetrios A; Vafiadaki Elizabeth; Mavroidis Manolis; Papadodima Stavroula A; Spiliopoulou Chara A; Kremastinos Dimitrios T; Kranias Evangelia G; Sanoudou Despina
Muscle LIM protein interacts with cofilin 2 and regulates F-actin dynamics in cardiac and skeletal muscle.
Molecular and cellular biology 2009;29(22):6046-58.
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2009: Jones W Keith; Fan Guo-Chang; Liao Siyun; Zhang Jun-Ming; Wang Yang; Weintraub Neal L; Kranias Evangelia G; Schultz Jo El; Lorenz John; Ren Xiaoping
Peripheral nociception associated with surgical incision elicits remote nonischemic cardioprotection via neurogenic activation of protein kinase C signaling.
Circulation 2009;120(11 Suppl):S1-9.
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2009: Wang Xiaohong; Zingarelli Basilia; O'Connor Michael; Zhang Pengyuan; Adeyemo Adeola; Kranias Evangelia G; Wang Yigang; Fan Guo-Chang
Overexpression of Hsp20 prevents endotoxin-induced myocardial dysfunction and apoptosis via inhibition of NF-kappaB activation.
Journal of molecular and cellular cardiology 2009;47(3):382-90.
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2009: Nicolaou Persoulla; Hajjar Roger J; Kranias Evangelia G
Role of protein phosphatase-1 inhibitor-1 in cardiac physiology and pathophysiology.
Journal of molecular and cellular cardiology 2009;47(3):365-71.
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2009: Liu Qinghang; Chen Xiongwen; Macdonnell Scott M; Kranias Evangelia G; Lorenz John N; Leitges Michael; Houser Steven R; Molkentin Jeffery D
Protein kinase C{alpha}, but not PKC{beta} or PKC{gamma}, regulates contractility and heart failure susceptibility: implications for ruboxistaurin as a novel therapeutic approach.
Circulation research 2009;105(2):194-200.
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2009: Pritchard Tracy J; Kranias Evangelia G
Junctin and the histidine-rich Ca2+ binding protein: potential roles in heart failure and arrhythmogenesis.
The Journal of physiology 2009;587(Pt 13):3125-33.
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2009: Zhao Wen; Fan Guo-Chang; Zhang Zhi-Guo; Bandyopadhyay Arun; Zhou Xiaoyang; Kranias Evangelia G
Protection of peroxiredoxin II on oxidative stress-induced cardiomyocyte death and apoptosis.
Basic research in cardiology 2009;104(4):377-89.
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2009: Yuan Qunying; Han Peidong; Dong Min; Ren Xiaoping; Zhou Xiaoyang; Chen Shan; Jones W Keith; Chu Guoxiang; Wang Hong-Sheng; Kranias Evangelia G
Partial downregulation of junctin enhances cardiac calcium cycling without eliciting ventricular arrhythmias in mice.
American journal of physiology. Heart and circulatory physiology 2009;296(5):H1484-90.
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2009: Nicolaou Persoulla; Rodriguez Patricia; Ren Xiaoping; Zhou Xiaoyang; Qian Jiang; Sadayappan Sakthivel; Mitton Bryan; Pathak Anand; Robbins Jeffrey; Hajjar Roger J; Jones Keith; Kranias Evangelia G
Inducible expression of active protein phosphatase-1 inhibitor-1 enhances basal cardiac function and protects against ischemia/reperfusion injury.
Circulation research 2009;104(8):1012-20.
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2009: Waggoner Jason R; Ginsburg Kenneth S; Mitton Bryan; Haghighi Kobra; Robbins Jeffrey; Bers Donald M; Kranias Evangelia G
Phospholamban overexpression in rabbit ventricular myocytes does not alter sarcoplasmic reticulum Ca transport.
American journal of physiology. Heart and circulatory physiology 2009;296(3):H698-703.
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2009: Diwan Abhinav; Matkovich Scot J; Yuan Qunying; Zhao Wen; Yatani Atsuko; Brown Joan Heller; Molkentin Jeffery D; Kranias Evangelia G; Dorn Gerald W
Endoplasmic reticulum-mitochondria crosstalk in NIX-mediated murine cell death.
The Journal of clinical investigation 2009;119(1):203-12.
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2009: Vafiadaki Elizabeth; Arvanitis Demetrios A; Pagakis Stamatis N; Papalouka Vasiliki; Sanoudou Despina; Kontrogianni-Konstantopoulos Aikaterini; Kranias Evangelia G
The anti-apoptotic protein HAX-1 interacts with SERCA2 and regulates its protein levels to promote cell survival.
Molecular biology of the cell 2009;20(1):306-18.
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2009: Vafiadaki Elizabeth; Papalouka Vasiliki; Arvanitis Demetrios A; Kranias Evangelia G; Sanoudou Despina
The role of SERCA2a/PLN complex, Ca(2+) homeostasis, and anti-apoptotic proteins in determining cell fate.
Pflügers Archiv : European journal of physiology 2009;457(3):687-700.
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2009: Nicolaou Persoulla; Kranias Evangelia G
Role of PP1 in the regulation of Ca cycling in cardiac physiology and pathophysiology.
Frontiers in bioscience : a journal and virtual library 2009;14():3571-85.
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2009: Chen Guoli; Zhou Xiaoyang; Pathak Anand; Dorn Gerald W; Kranias Evangelia G
The human G147D-protein phosphatase 1 inhibitor-1 polymorphism is not associated with altered clinical characteristics in heart failure.
Cardiology 2009;112(3):224-31.
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2008: Fan Guo-Chang; Zhou Xiaoyang; Wang Xiaohong; Song Guojie; Qian Jiang; Nicolaou Persoulla; Chen Guoli; Ren Xiaoping; Kranias Evangelia G
Heat shock protein 20 interacting with phosphorylated Akt reduces doxorubicin-triggered oxidative stress and cardiotoxicity.
Circulation research 2008;103(11):1270-9.
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2008: Arvanitis Demetrios A; Sanoudou Despina; Kolokathis Fotis; Vafiadaki Elizabeth; Papalouka Vasiliki; Kontrogianni-Konstantopoulos Aikaterini; Theodorakis George N; Paraskevaidis Ioannis A; Adamopoulos Stamatios; Dorn Gerald W; Kremastinos Dimitrios Th; Kranias Evangelia G
The Ser96Ala variant in histidine-rich calcium-binding protein is associated with life-threatening ventricular arrhythmias in idiopathic dilated cardiomyopathy.
European heart journal 2008;29(20):2514-25.
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2008: Chen Guoli; Zhou Xiaoyang; Nicolaou Persoulla; Rodriguez Patricia; Song Guojie; Mitton Bryan; Pathak Anand; Zachariah Amit; Fan Guo-Chang; Dorn Gerald W; Kranias Evangelia G
A human polymorphism of protein phosphatase-1 inhibitor-1 is associated with attenuated contractile response of cardiomyocytes to beta-adrenergic stimulation.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2008;22(6):1790-6.
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2008: Haghighi Kobra; Chen Guoli; Sato Yoji; Fan Guo-Chang; He Suiwen; Kolokathis Fotis; Pater Luke; Paraskevaidis Ioannis; Jones W Keith; Dorn Gerald W; Kremastinos Dimitrios Th; Kranias Evangelia G
A human phospholamban promoter polymorphism in dilated cardiomyopathy alters transcriptional regulation by glucocorticoids.
Human mutation 2008;29(5):640-7.
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2008: Pattison James Scott; Waggoner Jason R; James Jeanne; Martin Lisa; Gulick James; Osinska Hanna; Klevitsky Raisa; Kranias Evangelia G; Robbins Jeffrey
Phospholamban overexpression in transgenic rabbits.
Transgenic research 2008;17(2):157-70.
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2008: Zhang Yin Hua; Zhang Mei Hua; Sears Claire E; Emanuel Krzysztof; Redwood Charles; El-Armouche Ali; Kranias Evangelia G; Casadei Barbara
Reduced phospholamban phosphorylation is associated with impaired relaxation in left ventricular myocytes from neuronal NO synthase-deficient mice.
Circulation research 2008;102(2):242-9.
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2008: Fan Guo-Chang; Yuan Qunying; Kranias Evangelia G
Regulatory roles of junctin in sarcoplasmic reticulum calcium cycling and myocardial function.
Trends in cardiovascular medicine 2008;18(1):1-5.
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2007: Arvanitis Demetrios A; Vafiadaki Elizabeth; Fan Guo-Chang; Mitton Bryan A; Gregory Kimberly N; Del Monte Federica; Kontrogianni-Konstantopoulos Aikaterini; Sanoudou Despina; Kranias Evangelia G
Histidine-rich Ca-binding protein interacts with sarcoplasmic reticulum Ca-ATPase.
American journal of physiology. Heart and circulatory physiology 2007;293(3):H1581-9.
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2007: Zhou Xiaoyang; Fan Guo-Chang; Ren Xiaoping; Waggoner Jason R; Gregory Kimberly N; Chen Guoli; Jones W Keith; Kranias Evangelia G
Overexpression of histidine-rich Ca-binding protein protects against ischemia/reperfusion-induced cardiac injury.
Cardiovascular research 2007;75(3):487-97.
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2007: Rodriguez Patricia; Mitton Bryan; Nicolaou Persoulla; Chen Guoli; Kranias Evangelia G
Phosphorylation of human inhibitor-1 at Ser67 and/or Thr75 attenuates stimulatory effects of protein kinase A signaling in cardiac myocytes.
American journal of physiology. Heart and circulatory physiology 2007;293(1):H762-9.
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2007: Vafiadaki Elizabeth; Sanoudou Despina; Arvanitis Demetrios A; Catino Dawn H; Kranias Evangelia G; Kontrogianni-Konstantopoulos Aikaterini
Phospholamban interacts with HAX-1, a mitochondrial protein with anti-apoptotic function.
Journal of molecular biology 2007;367(1):65-79.
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2007: Vila-Petroff Martin; Salas Margarita A; Said Matilde; Valverde Carlos A; Sapia Luciana; Portiansky Enrique; Hajjar Roger J; Kranias Evangelia G; Mundiña-Weilenmann Cecilia; Mattiazzi Alicia
CaMKII inhibition protects against necrosis and apoptosis in irreversible ischemia-reperfusion injury.
Cardiovascular research 2007;73(4):689-98.
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2007: Pathak Anand; Baldwin Brent; Kranias Evangelia G
Key protein alterations associated with hyperdynamic cardiac function: insights based on proteomic analysis of the protein phosphatase 1 inhibitor-1 overexpressing hearts.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2007;48(1):30-6.
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2007: Yuan Qunying; Fan Guo-Chang; Dong Min; Altschafl Beth; Diwan Abhinav; Ren Xiaoping; Hahn Harvey H; Zhao Wen; Waggoner Jason R; Jones Larry R; Jones W Keith; Bers Donald M; Dorn Gerald W; Wang Hong-Sheng; Valdivia Héctor H; Chu Guoxiang; Kranias Evangelia G
Sarcoplasmic reticulum calcium overloading in junctin deficiency enhances cardiac contractility but increases ventricular automaticity.
Circulation 2007;115(3):300-9.
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2007: Fan Guo-Chang; Yuan Qunying; Zhao Wen; Chu Guoxiang; Kranias Evangelia G
Junctin is a prominent regulator of contractility in cardiomyocytes.
Biochemical and biophysical research communications 2007;352(3):617-22.
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2007: Kranias E G; Bers D M
Calcium and cardiomyopathies.
Sub-cellular biochemistry 2007;45():523-37.
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2006: Rodriguez Patricia; Mitton Bryan; Waggoner Jason R; Kranias Evangelia G
Identification of a novel phosphorylation site in protein phosphatase inhibitor-1 as a negative regulator of cardiac function.
The Journal of biological chemistry 2006;281(50):38599-608.
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2006: Fan Guo-Chang; Yuan Qunying; Song Guojie; Wang Yigang; Chen Guoli; Qian Jiang; Zhou Xiaoyang; Lee Yong J; Ashraf Muhammad; Kranias Evangelia G
Small heat-shock protein Hsp20 attenuates beta-agonist-mediated cardiac remodeling through apoptosis signal-regulating kinase 1.
Circulation research 2006;99(11):1233-42.
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2006: McGraw Dennis W; Fogel Kevin M; Kong Sue; Litonjua Augusto A; Kranias Evangelia G; Aronow Bruce J; Liggett Stephen B
Transcriptional response to persistent beta2-adrenergic receptor signaling reveals regulation of phospholamban, which alters airway contractility.
Physiological genomics 2006;27(2):171-7.
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2006: Vangheluwe Peter; Tjwa Marc; Van Den Bergh An; Louch William E; Beullens Monique; Dode Leonard; Carmeliet Peter; Kranias Evangelia; Herijgers Paul; Sipido Karin R; Raeymaekers Luc; Wuytack Frank
A SERCA2 pump with an increased Ca2+ affinity can lead to severe cardiac hypertrophy, stress intolerance and reduced life span.
Journal of molecular and cellular cardiology 2006;41(2):308-17.
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2006: Gregory Kimberly N; Kranias Evangelia G
Targeting sarcoplasmic reticulum calcium handling proteins as therapy for cardiac disease.
Hellenic journal of cardiology : HJC = Hellenike kardiologike epitheorese 2006;47(3):132-43.
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2006: Mattiazzi A; Mundiña-Weilenmann C; Vittone L; Said M; Kranias E G
The importance of the Thr17 residue of phospholamban as a phosphorylation site under physiological and pathological conditions.
Brazilian journal of medical and biological research = Revista brasileira de pesquisas médicas e biológicas / Sociedade Brasileira de Biofísica ... [et al.] 2006;39(5):563-72.
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2006: Gregory Kimberly N; Ginsburg Kenneth S; Bodi Ilona; Hahn Harvey; Marreez Yehia M A; Song Qiujing; Padmanabhan Prabhu A; Mitton Bryan A; Waggoner Jason R; Del Monte Federica; Park Woo Jin; Dorn Gerald W; Bers Donald M; Kranias Evangelia G
Histidine-rich Ca binding protein: a regulator of sarcoplasmic reticulum calcium sequestration and cardiac function.
Journal of molecular and cellular cardiology 2006;40(5):653-65.
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2006: Valverde Carlos A; Mundiña-Weilenmann Cecilia; Reyes Mariano; Kranias Evangelia G; Escobar Ariel L; Mattiazzi Alicia
Phospholamban phosphorylation sites enhance the recovery of intracellular Ca2+ after perfusion arrest in isolated, perfused mouse heart.
Cardiovascular research 2006;70(2):335-45.
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2006: Zhao Wen; Yuan Qunying; Qian Jiang; Waggoner Jason R; Pathak Anand; Chu Guoxiang; Mitton Bryan; Sun Xiaoyin; Jin Jay; Braz Julian C; Hahn Harvey S; Marreez Yehia; Syed Faisal; Pollesello Piero; Annila Arto; Wang Hong-Sheng; Schultz Jo El J; Molkentin Jeffery D; Liggett Stephen B; Dorn Gerald W; Kranias Evangelia G
The presence of Lys27 instead of Asn27 in human phospholamban promotes sarcoplasmic reticulum Ca2+-ATPase superinhibition and cardiac remodeling.
Circulation 2006;113(7):995-1004.
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2006: Gramolini Anthony O; Trivieri Maria G; Oudit Gavin Y; Kislinger Thomas; Li Wenping; Patel Mikin M; Emili Andrew; Kranias Evangelia G; Backx Peter H; Maclennan David H
Cardiac-specific overexpression of sarcolipin in phospholamban null mice impairs myocyte function that is restored by phosphorylation.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(7):2446-51.
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2006: Wu Yuejin; Shintani Ayumi; Grueter Chad; Zhang Rong; Hou Yue; Yang Jinying; Kranias Evangelia G; Colbran Roger J; Anderson Mark E
Suppression of dynamic Ca(2+) transient responses to pacing in ventricular myocytes from mice with genetic calmodulin kinase II inhibition.
Journal of molecular and cellular cardiology 2006;40(2):213-23.
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2006: Ji Yong; Zhao Wen; Li Bailing; Desantiago Jaime; Picht Eckard; Kaetzel Marcia A; Schultz Jo El J; Kranias Evangelia G; Bers Donald M; Dedman John R
Targeted inhibition of sarcoplasmic reticulum CaMKII activity results in alterations of Ca2+ homeostasis and cardiac contractility.
American journal of physiology. Heart and circulatory physiology 2006;290(2):H599-606.
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2006: Haghighi Kobra; Kolokathis Fotis; Gramolini Anthony O; Waggoner Jason R; Pater Luke; Lynch Roy A; Fan Guo-Chang; Tsiapras Dimitris; Parekh Rohan R; Dorn Gerald W; MacLennan David H; Kremastinos Dimitrios Th; Kranias Evangelia G
A mutation in the human phospholamban gene, deleting arginine 14, results in lethal, hereditary cardiomyopathy.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(5):1388-93.
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2006: Chu Guoxiang; Kranias Evangelia G
Phospholamban as a therapeutic modality in heart failure.
Novartis Foundation symposium 2006;274():156-71; discussion 172-5, 272-6.
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2005: Rodriguez P; Kranias E G
Phospholamban: a key determinant of cardiac function and dysfunction.
Archives des maladies du coeur et des vaisseaux 2005;98(12):1239-43.
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2005: Rodriguez Patricia; Mitton Bryan; Kranias Evangelia G
Phosphorylation of glutathione-S-transferase by protein kinase C-alpha implications for affinity-tag purification.
Biotechnology letters 2005;27(23-24):1869-73.
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2005: Mattiazzi Alicia; Mundiña-Weilenmann Cecilia; Guoxiang Chu; Vittone Leticia; Kranias Evangelia
Role of phospholamban phosphorylation on Thr17 in cardiac physiological and pathological conditions.
Cardiovascular research 2005;68(3):366-75.
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2005: Waggoner Jason R; Kranias Evangelia G
Role of phospholamban in the pathogenesis of heart failure.
Heart failure clinics 2005;1(2):207-18.
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2005: Fan Guo-Chang; Chu Guoxiang; Kranias Evangelia G
Hsp20 and its cardioprotection.
Trends in cardiovascular medicine 2005;15(4):138-41.
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2005: Sanoudou Despina; Vafiadaki Elizabeth; Arvanitis Demetrios A; Kranias Evangelia; Kontrogianni-Konstantopoulos Aikaterini
Array lessons from the heart: focus on the genome and transcriptome of cardiomyopathies.
Physiological genomics 2005;21(2):131-43.
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2005: Fan Guo-Chang; Ren Xiaoping; Qian Jiang; Yuan Qunying; Nicolaou Persoulla; Wang Yang; Jones W Keith; Chu Guoxiang; Kranias Evangelia G
Novel cardioprotective role of a small heat-shock protein, Hsp20, against ischemia/reperfusion injury.
Circulation 2005;111(14):1792-9.
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2005: Mundiña-Weilenmann Cecilia; Ferrero Paola; Said Matilde; Vittone Leticia; Kranias Evangelia G; Mattiazzi Alicia
Role of phosphorylation of Thr(17) residue of phospholamban in mechanical recovery during hypercapnic acidosis.
Cardiovascular research 2005;66(1):114-22.
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2005: Pathak Anand; del Monte Federica; Zhao Wen; Schultz Jo-El; Lorenz John N; Bodi Ilona; Weiser Doug; Hahn Harvey; Carr Andrew N; Syed Faisal; Mavila Nirmala; Jha Leena; Qian Jiang; Marreez Yehia; Chen Guoli; McGraw Dennis W; Heist E Kevin; Guerrero J Luis; DePaoli-Roach Anna A; Hajjar Roger J; Kranias Evangelia G
Enhancement of cardiac function and suppression of heart failure progression by inhibition of protein phosphatase 1.
Circulation research 2005;96(7):756-66.
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2004: Chu Guoxiang; Kerr Jaclyn P; Mitton Bryan; Egnaczyk Gregory F; Vazquez Jenny A; Shen Meilan; Kilby Greg W; Stevenson Tracy I; Maggio John E; Vockley Jerry; Rapundalo Stephen T; Kranias Evangelia G
Proteomic analysis of hyperdynamic mouse hearts with enhanced sarcoplasmic reticulum calcium cycling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(14):1725-7.
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2004: Szentesi Peter; Pignier Christophe; Egger Marcel; Kranias Evangelia G; Niggli Ernst
Sarcoplasmic reticulum Ca2+ refilling controls recovery from Ca2+-induced Ca2+ release refractoriness in heart muscle.
Circulation research 2004;95(8):807-13.
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2004: Haghighi Kobra; Gregory Kimberly N; Kranias Evangelia G
Sarcoplasmic reticulum Ca-ATPase-phospholamban interactions and dilated cardiomyopathy.
Biochemical and biophysical research communications 2004;322(4):1214-22.
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2004: Fan Guo-Chang; Gregory Kimberly N; Zhao Wen; Park Woo Jin; Kranias Evangelia G
Regulation of myocardial function by histidine-rich, calcium-binding protein.
American journal of physiology. Heart and circulatory physiology 2004;287(4):H1705-11.
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2004: Zhao Wen; Uehara Yoshiki; Chu Guoxiang; Song Qiujing; Qian Jiang; Young Karen; Kranias Evangelia G
Threonine-17 phosphorylation of phospholamban: a key determinant of frequency-dependent increase of cardiac contractility.
Journal of molecular and cellular cardiology 2004;37(2):607-12.
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2004: Sutliff Roy L; Conforti Laura; Weber Craig S; Kranias Evangelia G; Paul Richard J
Regulation of the spontaneous contractile activity of the portal vein by the sarcoplasmic reticulum: evidence from the phospholamban gene-ablated mouse.
Vascular pharmacology 2004;41(6):197-204.
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2004: Janczewski Andrzej M; Zahid Maliha; Lemster Bonnie H; Frye Carol S; Gibson Gregory; Higuchi Yoshihiro; Kranias Evangelia G; Feldman Arthur M; McTiernan Charles F
Phospholamban gene ablation improves calcium transients but not cardiac function in a heart failure model.
Cardiovascular research 2004;62(3):468-80.
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2004: Fan Guo-Chang; Chu Guoxiang; Mitton Bryan; Song Qiujing; Yuan Qunying; Kranias Evangelia G
Small heat-shock protein Hsp20 phosphorylation inhibits beta-agonist-induced cardiac apoptosis.
Circulation research 2004;94(11):1474-82.
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2004: Song Qiujing; Young Karen B; Chu Guoxiang; Gulick James; Gerst Michael; Grupp Ingrid L; Robbins Jeffrey; Kranias Evangelia G
Overexpression of phospholamban in slow-twitch skeletal muscle is associated with depressed contractile function and muscle remodeling.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2004;18(9):974-6.
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2004: Yatani Atsuko; Kim Song-Jung; Kudej Raymond K; Wang Qian; Depre Christophe; Irie Keiichi; Kranias Evangelia G; Vatner Stephen F; Vatner Dorothy E
Insights into cardioprotection obtained from study of cellular Ca2+ handling in myocardium of true hibernating mammals.
American journal of physiology. Heart and circulatory physiology 2004;286(6):H2219-28.
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2004: Engelhardt Stefan; Hein Lutz; Dyachenkow Vitaly; Kranias Evangelia G; Isenberg Gerrit; Lohse Martin J
Altered calcium handling is critically involved in the cardiotoxic effects of chronic beta-adrenergic stimulation.
Circulation 2004;109(9):1154-60.
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2004: Braz Julian C; Gregory Kimberly; Pathak Anand; Zhao Wen; Sahin Bogachan; Klevitsky Raisa; Kimball Thomas F; Lorenz John N; Nairn Angus C; Liggett Stephen B; Bodi Ilona; Wang Su; Schwartz Arnold; Lakatta Edward G; DePaoli-Roach Anna A; Robbins Jeffrey; Hewett Timothy E; Bibb James A; Westfall Margaret V; Kranias Evangelia G; Molkentin Jeffery D
PKC-alpha regulates cardiac contractility and propensity toward heart failure.
Nature medicine 2004;10(3):248-54.
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2004: Pan Yan; Kislinger Thomas; Gramolini Anthony O; Zvaritch Elena; Kranias Evangelia G; MacLennan David H; Emili Andrew
Identification of biochemical adaptations in hyper- or hypocontractile hearts from phospholamban mutant mice by expression proteomics.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(8):2241-6.
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2004: Gregory Kimberly N; Hahn Harvey; Haghighi Kobra; Marreez Yehia; Odley Amy; Dorn Gerald W; Kranias Evangelia G
Increased particulate partitioning of PKC epsilon reverses susceptibility of phospholamban knockout hearts to ischemic injury.
Journal of molecular and cellular cardiology 2004;36(2):313-8.
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2004: Chu Guoxiang; Egnaczyk Gregory F; Zhao Wen; Jo Su-Hyun; Fan Guo-Chang; Maggio John E; Xiao Rui-Ping; Kranias Evangelia G
Phosphoproteome analysis of cardiomyocytes subjected to beta-adrenergic stimulation: identification and characterization of a cardiac heat shock protein p20.
Circulation research 2004;94(2):184-93.
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2003: Said M; Vittone L; Mundina-Weilenmann C; Ferrero P; Kranias E G; Mattiazzi A
Role of dual-site phospholamban phosphorylation in the stunned heart: insights from phospholamban site-specific mutants.
American journal of physiology. Heart and circulatory physiology 2003;285(3):H1198-205.
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2003: MacLennan David H; Kranias Evangelia G
Phospholamban: a crucial regulator of cardiac contractility.
Nature reviews. Molecular cell biology 2003;4(7):566-77.
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2003: Schmidt Albrecht G; Haghighi Kobra; Frank Beate; Pater Luke; Dorn Gerald W; Walsh Richard A; Kranias Evangelia G
Polymorphic SERCA2a variants do not account for inter-individual differences in phospholamban-SERCA2a interactions in human heart failure.
Journal of molecular and cellular cardiology 2003;35(7):867-70.
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2003: Brittsan Angela G; Ginsburg Kenneth S; Chu Guoxiang; Yatani Atsuko; Wolska Beata M; Schmidt Albrecht G; Asahi Michio; MacLennan David H; Bers Donald M; Kranias Evangelia G
Chronic SR Ca2+-ATPase inhibition causes adaptive changes in cellular Ca2+ transport.
Circulation research 2003;92(7):769-76.
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2003: Haghighi Kobra; Kolokathis Fotis; Pater Luke; Lynch Roy A; Asahi Michio; Gramolini Anthony O; Fan Guo-Chang; Tsiapras Dimitris; Hahn Harvey S; Adamopoulos Stamatis; Liggett Stephen B; Dorn Gerald W; MacLennan David H; Kremastinos Dimitrios T; Kranias Evangelia G
Human phospholamban null results in lethal dilated cardiomyopathy revealing a critical difference between mouse and human.
The Journal of clinical investigation 2003;111(6):869-76.
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2003: Song Qiujing; Schmidt Albrecht G; Hahn Harvey S; Carr Andrew N; Frank Beate; Pater Luke; Gerst Mike; Young Karen; Hoit Brian D; McConnell Bradley K; Haghighi Kobra; Seidman Christine E; Seidman Jonathan G; Dorn Gerald W; Kranias Evangelia G
Rescue of cardiomyocyte dysfunction by phospholamban ablation does not prevent ventricular failure in genetic hypertrophy.
The Journal of clinical investigation 2003;111(6):859-67.
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2003: Dash Rajesh; Schmidt Albrecht G; Pathak Anand; Gerst Michael J; Biniakiewicz Danuta; Kadambi Vivek J; Hoit Brian D; Abraham William T; Kranias Evangelia G
Differential regulation of p38 mitogen-activated protein kinase mediates gender-dependent catecholamine-induced hypertrophy.
Cardiovascular research 2003;57(3):704-14.
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2003: Schmitt Joachim P; Kamisago Mitsuhiro; Asahi Michio; Li Guo Hua; Ahmad Ferhaan; Mende Ulrike; Kranias Evangelia G; MacLennan David H; Seidman J G; Seidman Christine E
Dilated cardiomyopathy and heart failure caused by a mutation in phospholamban.
Science (New York, N.Y.) 2003;299(5611):1410-3.
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2003: Isoda Takayoshi; Paolocci Nazareno; Haghighi Kobra; Wang Congrong; Wang Yibin; Georgakopoulos Dimitrios; Servillo Giuseppe; Della Fazia Maria Agnese; Kranias Evangelia G; Depaoli-Roach Anna A; Sassone-Corsi Paolo; Kass David A
Novel regulation of cardiac force-frequency relation by CREM (cAMP response element modulator).
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2003;17(2):144-51.
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2003: Cross Heather R; Kranias Evangelia G; Murphy Elizabeth; Steenbergen Charles
Ablation of PLB exacerbates ischemic injury to a lesser extent in female than male mice: protective role of NO.
American journal of physiology. Heart and circulatory physiology 2003;284(2):H683-90.
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2003: Sato Yoji; Schmidt Albrecht G; Kiriazis Helen; Hoit Brian D; Kranias Evangelia G
Compensated hypertrophy of cardiac ventricles in aged transgenic FVB/N mice overexpressing calsequestrin.
Molecular and cellular biochemistry 2003;242(1-2):19-25.
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2003: Zhao Wen; Frank Konrad F; Chu Guoxiang; Gerst Michael J; Schmidt Albrecht G; Ji Yong; Periasamy Muthu; Kranias Evangelia G
Combined phospholamban ablation and SERCA1a overexpression result in a new hyperdynamic cardiac state.
Cardiovascular research 2003;57(1):71-81.
-
2002: Chu Guoxiang; Haghighi Kobra; Kranias Evangelia G
From mouse to man: understanding heart failure through genetically altered mouse models.
Journal of cardiac failure 2002;8(6 Suppl):S432-49.
-
2002: Schmidt Albrecht G; Zhai Jing; Carr Andrew N; Gerst Mike J; Lorenz John N; Pollesello Piero; Annila Arto; Hoit Brian D; Kranias Evangelia G
Structural and functional implications of the phospholamban hinge domain: impaired SR Ca2+ uptake as a primary cause of heart failure.
Cardiovascular research 2002;56(2):248-59.
-
2002: Schmidt Albrecht G; Gerst Mike; Zhai Jing; Carr Andrew N; Pater Luke; Kranias Evangelia G; Hoit Brian D
Evaluation of left ventricular diastolic function from spectral and color M-mode Doppler in genetically altered mice.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography 2002;15(10 Pt 1):1065-73.
-
2002: Kranias Evangelia
Introduction.
Journal of molecular and cellular cardiology 2002;34(8):883.
-
2002: Carr Andrew N; Kranias Evangelia G
Thyroid hormone regulation of calcium cycling proteins.
Thyroid : official journal of the American Thyroid Association 2002;12(6):453-7.
-
2002: Carr Andrew N; Schmidt Albrecht G; Suzuki Yoichi; del Monte Federica; Sato Yoji; Lanner Carita; Breeden Kristine; Jing Shao-Ling; Allen Patrick B; Greengard Paul; Yatani Atsuko; Hoit Brian D; Grupp Ingrid L; Hajjar Roger J; DePaoli-Roach Anna A; Kranias Evangelia G
Type 1 phosphatase, a negative regulator of cardiac function.
Molecular and cellular biology 2002;22(12):4124-35.
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2002: Wolska Beata M; Arteaga Grace M; Peña James R; Nowak Grzegorz; Phillips Ronald M; Sahai Shalini; de Tombe Pieter P; Martin Anne F; Kranias Evangelia G; Solaro R John
Expression of slow skeletal troponin I in hearts of phospholamban knockout mice alters the relaxant effect of beta-adrenergic stimulation.
Circulation research 2002;90(8):882-8.
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2002: Chu Guoxiang; Carr Andrew N; Young Karen B; Lester J William; Yatani Atsuko; Sanbe Atsushi; Colbert Melissa C; Schwartz Steven M; Frank Konrad F; Lampe Paul D; Robbins Jeffrey; Molkentin Jeffery D; Kranias Evangelia G
Enhanced myocyte contractility and Ca2+ handling in a calcineurin transgenic model of heart failure.
Cardiovascular research 2002;54(1):105-16.
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2002: Pi YeQing; Kemnitz Kara R; Zhang Dahua; Kranias Evangelia G; Walker Jeffery W
Phosphorylation of troponin I controls cardiac twitch dynamics: evidence from phosphorylation site mutants expressed on a troponin I-null background in mice.
Circulation research 2002;90(6):649-56.
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2002: Li Yanxia; Kranias Evangelia G; Mignery Gregory A; Bers Donald M
Protein kinase A phosphorylation of the ryanodine receptor does not affect calcium sparks in mouse ventricular myocytes.
Circulation research 2002;90(3):309-16.
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2002: Kiriazis Helen; Sato Yoji; Kadambi Vivek J; Schmidt Albrecht G; Gerst Michael J; Hoit Brian D; Kranias Evangelia G
Hypertrophy and functional alterations in hyperdynamic phospholamban-knockout mouse hearts under chronic aortic stenosis.
Cardiovascular research 2002;53(2):372-81.
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2002: Brixius Klara; Savvidou-Zaroti Persephone; Mehlhorn Uwe; Bloch Wilhelm; Kranias Evangelia G; Schwinger Robert H G
Increased Ca2+-sensitivity of myofibrillar tension in heart failure and its functional implication.
Basic research in cardiology 2002;97 Suppl 1():I111-7.
-
2002: Frank Konrad F; Bölck Birgit; Brixius Klara; Kranias Evangelia G; Schwinger Robert H G
Modulation of SERCA: implications for the failing human heart.
Basic research in cardiology 2002;97 Suppl 1():I72-8.
-
2002: Chu Guoxiang; Kranias Evangelia G
Functional interplay between dual site phospholambam phosphorylation: insights from genetically altered mouse models.
Basic research in cardiology 2002;97 Suppl 1():I43-8.
-
2002: Paul R J; Shull G E; Kranias E G
The sarcoplasmic reticulum and smooth muscle function: evidence from transgenic mice.
Novartis Foundation symposium 2002;246():228-38; discussion 238-43, 272-6.
-
2001: Frank K F; Mesnard-Rouiller L; Chu G; Young K B; Zhao W; Haghighi K; Sato Y; Kranias E G
Structure and expression of the mouse cardiac calsequestrin gene.
Basic research in cardiology 2001;96(6):636-44.
-
2001: Schmidt A G; Edes I; Kranias E G
Phospholamban: a promising therapeutic target in heart failure?
Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy 2001;15(5):387-96.
-
2001: Nobe K; Sutliff R L; Kranias E G; Paul R J
Phospholamban regulation of bladder contractility: evidence from gene-altered mouse models.
The Journal of physiology 2001;535(Pt 3):867-78.
-
2001: Sato Y; Schmidt A G; Kiriazis H; Hoit B D; Kranias E G
Letter to the editor: Re-evaluation of heart failure in transgenic mice with impaired SR Ca2+ release.
Journal of molecular and cellular cardiology 2001;33(9):1757-9.
-
2001: Carr A N; Sutliff R L; Weber C S; Allen P B; Greengard P; de Lanerolle P; Kranias E G; Paul R J
Is myosin phosphatase regulated in vivo by inhibitor-1? Evidence from inhibitor-1 knockout mice.
The Journal of physiology 2001;534(Pt. 2):357-66.
-
2001: Dash R; Frank K F; Carr A N; Moravec C S; Kranias E G
Gender influences on sarcoplasmic reticulum Ca2+-handling in failing human myocardium.
Journal of molecular and cellular cardiology 2001;33(7):1345-53.
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2001: Aronow B J; Toyokawa T; Canning A; Haghighi K; Delling U; Kranias E; Molkentin J D; Dorn G W
Divergent transcriptional responses to independent genetic causes of cardiac hypertrophy.
Physiological genomics 2001;6(1):19-28.
-
2001: Haghighi K; Schmidt A G; Hoit B D; Brittsan A G; Yatani A; Lester J W; Zhai J; Kimura Y; Dorn G W; MacLennan D H; Kranias E G
Superinhibition of sarcoplasmic reticulum function by phospholamban induces cardiac contractile failure.
The Journal of biological chemistry 2001;276(26):24145-52.
-
2001: Slack J P; Grupp I L; Dash R; Holder D; Schmidt A; Gerst M J; Tamura T; Tilgmann C; James P F; Johnson R; Gerdes A M; Kranias E G
The enhanced contractility of the phospholamban-deficient mouse heart persists with aging.
Journal of molecular and cellular cardiology 2001;33(5):1031-40.
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2001: Sato Y; Kiriazis H; Yatani A; Schmidt A G; Hahn H; Ferguson D G; Sako H; Mitarai S; Honda R; Mesnard-Rouiller L; Frank K F; Beyermann B; Wu G; Fujimori K; Dorn G W; Kranias E G
Rescue of contractile parameters and myocyte hypertrophy in calsequestrin overexpressing myocardium by phospholamban ablation.
The Journal of biological chemistry 2001;276(12):9392-9.
-
2001: Shannon T R; Chu G; Kranias E G; Bers D M
Phospholamban decreases the energetic efficiency of the sarcoplasmic reticulum Ca pump.
The Journal of biological chemistry 2001;276(10):7195-201.
-
2001: Dash R; Kadambi V; Schmidt A G; Tepe N M; Biniakiewicz D; Gerst M J; Canning A M; Abraham W T; Hoit B D; Liggett S B; Lorenz J N; Dorn G W; Kranias E G
Interactions between phospholamban and beta-adrenergic drive may lead to cardiomyopathy and early mortality.
Circulation 2001;103(6):889-96.
-
2000: Brittsan A G; Kranias E G
Phospholamban and cardiac contractile function.
Journal of molecular and cellular cardiology 2000;32(12):2131-9.
-
2000: Chu G; Lester J W; Young K B; Luo W; Zhai J; Kranias E G
A single site (Ser16) phosphorylation in phospholamban is sufficient in mediating its maximal cardiac responses to beta -agonists.
The Journal of biological chemistry 2000;275(49):38938-43.
-
2000: Frank K; Tilgmann C; Shannon T R; Bers D M; Kranias E G
Regulatory role of phospholamban in the efficiency of cardiac sarcoplasmic reticulum Ca2+ transport.
Biochemistry 2000;39(46):14176-82.
-
2000: Schmidt A G; Kadambi V J; Ball N; Sato Y; Walsh R A; Kranias E G; Hoit B D
Cardiac-specific overexpression of calsequestrin results in left ventricular hypertrophy, depressed force-frequency relation and pulsus alternans in vivo.
Journal of molecular and cellular cardiology 2000;32(9):1735-44.
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2000: Zvaritch E; Backx P H; Jirik F; Kimura Y; de Leon S; Schmidt A G; Hoit B D; Lester J W; Kranias E G; MacLennan D H
The transgenic expression of highly inhibitory monomeric forms of phospholamban in mouse heart impairs cardiac contractility.
The Journal of biological chemistry 2000;275(20):14985-91.
-
2000: Brittsan A G; Carr A N; Schmidt A G; Kranias E G
Maximal inhibition of SERCA2 Ca(2+) affinity by phospholamban in transgenic hearts overexpressing a non-phosphorylatable form of phospholamban.
The Journal of biological chemistry 2000;275(16):12129-35.
-
2000: Zhai J; Schmidt A G; Hoit B D; Kimura Y; MacLennan D H; Kranias E G
Cardiac-specific overexpression of a superinhibitory pentameric phospholamban mutant enhances inhibition of cardiac function in vivo.
The Journal of biological chemistry 2000;275(14):10538-44.
-
2000: Hoit B D; Kadambi V J; Tramuta D A; Ball N; Kranias E G; Walsh R A
Influence of sarcoplasmic reticulum calcium loading on mechanical and relaxation restitution.
American journal of physiology. Heart and circulatory physiology 2000;278(3):H958-63.
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2000: Li L; Desantiago J; Chu G; Kranias E G; Bers D M
Phosphorylation of phospholamban and troponin I in beta-adrenergic-induced acceleration of cardiac relaxation.
American journal of physiology. Heart and circulatory physiology 2000;278(3):H769-79.
-
2000: Schwinger R H; Brixius K; Savvidou-Zaroti P; Bölck B; Zobel C; Frank K; Kranias E G; Hoischen S; Erdmann E
The enhanced contractility in phospholamban deficient mouse hearts is not associated with alterations in (Ca2+)-sensitivity or myosin ATPase-activity of the contractile proteins.
Basic research in cardiology 2000;95(1):12-8.
-
2000: Kranias E G
Commentary on the special topic section on the use of transgenic models.
Annual review of physiology 2000;62():965-9.
-
2000: Kiriazis H; Kranias E G
Genetically engineered models with alterations in cardiac membrane calcium-handling proteins.
Annual review of physiology 2000;62():321-51.
-
1999: Tepe N M; Lorenz J N; Yatani A; Dash R; Kranias E G; Dorn G W; Liggett S B
Altering the receptor-effector ratio by transgenic overexpression of type V adenylyl cyclase: enhanced basal catalytic activity and function without increased cardiomyocyte beta-adrenergic signalling.
Biochemistry 1999;38(50):16706-13.
-
1999: Hoit B D; Tramuta D A; Kadambi V J; Dash R; Ball N; Kranias E G; Walsh R A
Influence of transgenic overexpression of phospholamban on postextrasystolic potentiation.
Journal of molecular and cellular cardiology 1999;31(11):2007-15.
-
1999: Lalli M J; Shimizu S; Sutliff R L; Kranias E G; Paul R J
[Ca2+]i homeostasis and cyclic nucleotide relaxation in aorta of phospholamban-deficient mice.
The American journal of physiology 1999;277(3 Pt 2):H963-70.
-
1999: Brittsan A G; Kiss E; Edes I; Grupp I L; Grupp G; Kranias E G
The effect of isoproterenol on phospholamban-deficient mouse hearts with altered thyroid conditions.
Journal of molecular and cellular cardiology 1999;31(9):1725-37.
-
1999: Yatani A; Frank K; Sako H; Kranias E G; Dorn G W
Cardiac-specific overexpression of Galphaq alters excitation-contraction coupling in isolated cardiac myocytes.
Journal of molecular and cellular cardiology 1999;31(7):1327-36.
-
1999: Kadambi V J; Ball N; Kranias E G; Walsh R A; Hoit B D
Modulation of force-frequency relation by phospholamban in genetically engineered mice.
The American journal of physiology 1999;276(6 Pt 2):H2245-50.
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1999: Sutliff R L; Hoying J B; Kadambi V J; Kranias E G; Paul R J
Phospholamban is present in endothelial cells and modulates endothelium-dependent relaxation. Evidence from phospholamban gene-ablated mice.
Circulation research 1999;84(3):360-4.
-
1998: Kadambi V J; Kranias E G
Genetically engineered mice: model systems for left ventricular failure.
Journal of cardiac failure 1998;4(4):349-61.
-
1998: Chu G; Li L; Sato Y; Harrer J M; Kadambi V J; Hoit B D; Bers D M; Kranias E G
Pentameric assembly of phospholamban facilitates inhibition of cardiac function in vivo.
The Journal of biological chemistry 1998;273(50):33674-80.
-
1998: Sato Y; Ferguson D G; Sako H; Dorn G W; Kadambi V J; Yatani A; Hoit B D; Walsh R A; Kranias E G
Cardiac-specific overexpression of mouse cardiac calsequestrin is associated with depressed cardiovascular function and hypertrophy in transgenic mice.
The Journal of biological chemistry 1998;273(43):28470-7.
-
1998: Chu G; Ferguson D G; Edes I; Kiss E; Sato Y; Kranias E G
Phospholamban ablation and compensatory responses in the mammalian heart.
Annals of the New York Academy of Sciences 1998;853():49-62.
-
1998: Kiss E; Brittsan A G; Edes I; Grupp I L; Grupp G; Kranias E G
Thyroid hormone-induced alterations in phospholamban-deficient mouse hearts.
Circulation research 1998;83(6):608-13.
-
1998: Kadambi V J; Koss K L; Grupp I L; Kranias E G
Phospholamban modulates murine atrial contractile parameters and responses to beta-adrenergic agonists.
Journal of molecular and cellular cardiology 1998;30(7):1275-84.
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1998: Takeishi Y; Chu G; Kirkpatrick D M; Li Z; Wakasaki H; Kranias E G; King G L; Walsh R A
In vivo phosphorylation of cardiac troponin I by protein kinase Cbeta2 decreases cardiomyocyte calcium responsiveness and contractility in transgenic mouse hearts.
The Journal of clinical investigation 1998;102(1):72-8.
-
1998: Li L; Chu G; Kranias E G; Bers D M
Cardiac myocyte calcium transport in phospholamban knockout mouse: relaxation and endogenous CaMKII effects.
The American journal of physiology 1998;274(4 Pt 2):H1335-47.
-
1998: Masaki H; Sako H; Kadambi V J; Sato Y; Kranias E G; Yatani A
Overexpression of phospholamban alters inactivation kinetics of L-type Ca2+ channel currents in mouse atrial myocytes.
Journal of molecular and cellular cardiology 1998;30(2):317-25.
-
1998: Luo W; Chu G; Sato Y; Zhou Z; Kadambi V J; Kranias E G
Transgenic approaches to define the functional role of dual site phospholamban phosphorylation.
The Journal of biological chemistry 1998;273(8):4734-9.
-
1998: Zhou M; Sutliff R L; Paul R J; Lorenz J N; Hoying J B; Haudenschild C C; Yin M; Coffin J D; Kong L; Kranias E G; Luo W; Boivin G P; Duffy J J; Pawlowski S A; Doetschman T
Fibroblast growth factor 2 control of vascular tone.
Nature medicine 1998;4(2):201-7.
-
1997: Lorenz J N; Kranias E G
Regulatory effects of phospholamban on cardiac function in intact mice.
The American journal of physiology 1997;273(6 Pt 2):H2826-31.
-
1997: Haghighi K; Kadambi V J; Koss K L; Luo W; Harrer J M; Ponniah S; Zhou Z; Kranias E G
In vitro and in vivo promoter analyses of the mouse phospholamban gene.
Gene 1997;203(2):199-207.
-
1997: Sako H; Green S A; Kranias E G; Yatani A
Modulation of cardiac Ca2+ channels by isoproterenol studied in transgenic mice with altered SR Ca2+ content.
The American journal of physiology 1997;273(5 Pt 1):C1666-72.
-
1997: Kadambi V J; Kranias E G
Phospholamban: a protein coming of age.
Biochemical and biophysical research communications 1997;239(1):1-5.
-
1997: Chu G; Dorn G W; Luo W; Harrer J M; Kadambi V J; Walsh R A; Kranias E G
Monomeric phospholamban overexpression in transgenic mouse hearts.
Circulation research 1997;81(4):485-92.
-
1997: Slack J P; Grupp I L; Luo W; Kranias E G
Phospholamban ablation enhances relaxation in the murine soleus.
The American journal of physiology 1997;273(1 Pt 1):C1-6.
-
1997: Slack J P; Grupp I L; Ferguson D G; Rosenthal N; Kranias E G
Ectopic expression of phospholamban in fast-twitch skeletal muscle alters sarcoplasmic reticulum Ca2+ transport and muscle relaxation.
The Journal of biological chemistry 1997;272(30):18862-8.
-
1997: Lalli J; Harrer J M; Luo W; Kranias E G; Paul R J
Targeted ablation of the phospholamban gene is associated with a marked decrease in sensitivity in aortic smooth muscle.
Circulation research 1997;80(4):506-13.
-
1997: Kiss E; Edes I; Sato Y; Luo W; Liggett S B; Kranias E G
beta-Adrenergic regulation of cAMP and protein phosphorylation in phospholamban-knockout mouse hearts.
The American journal of physiology 1997;272(2 Pt 2):H785-90.
-
1997: Masaki H; Sato Y; Luo W; Kranias E G; Yatani A
Phospholamban deficiency alters inactivation kinetics of L-type Ca2+ channels in mouse ventricular myocytes.
The American journal of physiology 1997;272(2 Pt 2):H606-12.
-
1997: Harrer J M; Haghighi K; Kim H W; Ferguson D G; Kranias E G
Coordinate regulation of SR Ca(2+)-ATPase and phospholamban expression in developing murine heart.
The American journal of physiology 1997;272(1 Pt 2):H57-66.
-
1997: Koss K L; Grupp I L; Kranias E G
The relative phospholamban and SERCA2 ratio: a critical determinant of myocardial contractility.
Basic research in cardiology 1997;92 Suppl 1():17-24.
-
1996: Chu G; Luo W; Slack J P; Tilgmann C; Sweet W E; Spindler M; Saupe K W; Boivin G P; Moravec C S; Matlib M A; Grupp I L; Ingwall J S; Kranias E G
Compensatory mechanisms associated with the hyperdynamic function of phospholamban-deficient mouse hearts.
Circulation research 1996;79(6):1064-76.
-
1996: Koss K L; Kranias E G
Phospholamban: a prominent regulator of myocardial contractility.
Circulation research 1996;79(6):1059-63.
-
1996: Wolska B M; Stojanovic M O; Luo W; Kranias E G; Solaro R J
Effect of ablation of phospholamban on dynamics of cardiac myocyte contraction and intracellular Ca2+.
The American journal of physiology 1996;271(1 Pt 1):C391-7.
-
1996: Luo W; Wolska B M; Grupp I L; Harrer J M; Haghighi K; Ferguson D G; Slack J P; Grupp G; Doetschman T; Solaro R J; Kranias E G
Phospholamban gene dosage effects in the mammalian heart.
Circulation research 1996;78(5):839-47.
-
1996: Kadambi V J; Ponniah S; Harrer J M; Hoit B D; Dorn G W; Walsh R A; Kranias E G
Cardiac-specific overexpression of phospholamban alters calcium kinetics and resultant cardiomyocyte mechanics in transgenic mice.
The Journal of clinical investigation 1996;97(2):533-9.
-
1995: Kiss E; Ball N A; Kranias E G; Walsh R A
Differential changes in cardiac phospholamban and sarcoplasmic reticular Ca(2+)-ATPase protein levels. Effects on Ca2+ transport and mechanics in compensated pressure-overload hypertrophy and congestive heart failure.
Circulation research 1995;77(4):759-64.
-
1995: Szymanska G; Grupp I L; Slack J P; Harrer J M; Kranias E G
Alterations in sarcoplasmic reticulum calcium uptake, relaxation parameters and their responses to beta-adrenergic agonists in the developing rabbit heart.
Journal of molecular and cellular cardiology 1995;27(9):1819-29.
-
1995: Hoit B D; Khoury S F; Kranias E G; Ball N; Walsh R A
In vivo echocardiographic detection of enhanced left ventricular function in gene-targeted mice with phospholamban deficiency.
Circulation research 1995;77(3):632-7.
-
1995: Koss K L; Ponniah S; Jones W K; Grupp I L; Kranias E G
Differential phospholamban gene expression in murine cardiac compartments. Molecular and physiological analyses.
Circulation research 1995;77(2):342-53.
-
1995: Edes I; Kiss E; Kitada Y; Powers F M; Papp J G; Kranias E G; Solaro R J
Effects of Levosimendan, a cardiotonic agent targeted to troponin C, on cardiac function and on phosphorylation and Ca2+ sensitivity of cardiac myofibrils and sarcoplasmic reticulum in guinea pig heart.
Circulation research 1995;77(1):107-13.
-
1995: Harrer J M; Kiss E; Kranias E G
Application of the immunoblot technique for quantitation of protein levels in cardiac homogenates.
BioTechniques 1995;18(6):995-8.
-
1995: Harrer J M; Ponniah S; Ferguson D G; Kranias E G
Expression of phospholamban in C2C12 cells and regulation of endogenous SERCA1 activity.
Molecular and cellular biochemistry 1995;146(1):13-21.
-
1994: Harrer J M; Kranias E G
Characterization of the molecular form of cardiac phospholamban.
Molecular and cellular biochemistry 1994;140(2):185-93.
-
1994: Luo W; Grupp I L; Harrer J; Ponniah S; Grupp G; Duffy J J; Doetschman T; Kranias E G
Targeted ablation of the phospholamban gene is associated with markedly enhanced myocardial contractility and loss of beta-agonist stimulation.
Circulation research 1994;75(3):401-9.
-
1994: Kiss E; Jakab G; Kranias E G; Edes I
Thyroid hormone-induced alterations in phospholamban protein expression. Regulatory effects on sarcoplasmic reticulum Ca2+ transport and myocardial relaxation.
Circulation research 1994;75(2):245-51.
-
1994: Jakab G; Kiss E; Kranias E G; Edes I
Effect of thyroid status on basal phosphorylation of cardiac myofibrillar phosphoproteins in rats.
Cardioscience 1994;5(1):19-24.
-
1993: Jakab G; Kiss E; Kranias E G; Edes I
Effect of thyroid status on phosphatidylinositols in rat heart.
Cardioscience 1993;4(4):257-62.
-
1993: Hardin C D; Zhang C; Kranias E G; Steenaart N A; Raeymaekers L; Paul R J
Regulation of glycolytically fueled Ca2+ uptake in smooth muscle plasmalemmal vesicles by phosphorylation.
The American journal of physiology 1993;265(4 Pt 2):H1326-33.
-
1993: Talosi L; Edes I; Kranias E G
Intracellular mechanisms mediating reversal of beta-adrenergic stimulation in intact beating hearts.
The American journal of physiology 1993;264(3 Pt 2):H791-7.
-
1992: Ganim J R; Luo W; Ponniah S; Grupp I; Kim H W; Ferguson D G; Kadambi V; Neumann J C; Doetschman T; Kranias E G
Mouse phospholamban gene expression during development in vivo and in vitro.
Circulation research 1992;71(5):1021-30.
-
1992: Szymanska G; Kim H W; Cuppoletti J; Kranias E G
Regulation of the skeletal sarcoplasmic reticulum Ca(2+)-ATPase by phospholamban and negatively charged phospholipids in reconstituted phospholipid vesicles.
Molecular and cellular biochemistry 1992;114(1-2):65-71.
-
1992: Zhang C; Paul R J; Kranias E G
Calmodulin stimulation of smooth muscle plasmalemmal vesicle Ca2+ uptake: direct or indirect effect?
The American journal of physiology 1992;263(2 Pt 2):H366-71.
-
1992: Talosi L; Kranias E G
Effect of alpha-adrenergic stimulation on activation of protein kinase C and phosphorylation of proteins in intact rabbit hearts.
Circulation research 1992;70(4):670-8.
-
1992: Steenaart N A; Ganim J R; Di Salvo J; Kranias E G
The phospholamban phosphatase associated with cardiac sarcoplasmic reticulum is a type 1 enzyme.
Archives of biochemistry and biophysics 1992;293(1):17-24.
-
1991: Edes I; Talosi L; Kranias E G
The effect of alpha-adrenergic agents and protein kinase C activators on protein phosphorylation in isolated guinea pig hearts.
European heart journal 1991;12 Suppl F():143-4.
-
1991: Edes I; Talosi L; Kranias E G
Effect of alpha adrenergic agents and phorbol esters on phosphorylation of sarcolemmal proteins in beating guinea pig hearts.
Cardiovascular research 1991;25(6):510-5.
-
1991: Gupta R C; Young E F; Ferguson D G; Kranias E G
Regulation of rat cardiac nuclei-associated Mg(2+)-NTPase by phosphorylation.
Molecular and cellular biochemistry 1991;102(2):165-72.
-
1991: Szymanska G; Kim H W; Kranias E G
Reconstitution of the skeletal sarcoplasmic reticulum Ca2(+)-pump: influence of negatively charged phospholipids.
Biochimica et biophysica acta 1991;1091(2):127-34.
-
1990: Edes I; Kranias E G
The effect of phorbol esters and diacylglycerol analogues on the basal phosphoinositide turnover in isolated guinea pig hearts.
Cardioscience 1990;1(4):265-74.
-
1990: Davis B A; Edes I; Gupta R C; Young E F; Kim H W; Steenaart N A; Szymanska G; Kranias E G
The role of phospholamban in the regulation of calcium transport by cardiac sarcoplasmic reticulum.
Molecular and cellular biochemistry 1990;99(2):83-8.
-
1990: Edes I; Kranias E G
Phospholamban and troponin I are substrates for protein kinase C in vitro but not in intact beating guinea pig hearts.
Circulation research 1990;67(2):394-400.
-
1990: Szymanska G; Kim H W; Cuppoletti J; Kranias E G
Regulation of the skeletal sarcoplasmic reticulum Ca2+ pump by phospholamban in reconstituted phospholipid vesicles.
Membrane biochemistry 1990;9(3):191-202.
-
1990: Edes I; Kranias E G
Characterization of cytoplasmic and membrane-associated phosphatidylinositol 4,5-biphosphate phospholipase C activities in guinea pig ventricles.
Basic research in cardiology 1990;85(1):78-87.
-
1990: Kim H W; Steenaart N A; Ferguson D G; Kranias E G
Functional reconstitution of the cardiac sarcoplasmic reticulum Ca2(+)-ATPase with phospholamban in phospholipid vesicles.
The Journal of biological chemistry 1990;265(3):1702-9.
-
1989: Edes I; Solaro R J; Kranias E G
Changes in phosphoinositide turnover in isolated guinea pig hearts stimulated with isoproterenol.
Circulation research 1989;65(4):989-96.
-
1989: Gupta R C; Kranias E G
Purification and characterization of a calcium-calmodulin-dependent phospholamban kinase from canine myocardium.
Biochemistry 1989;28(14):5909-16.
-
1989: Rapundalo S T; Solaro R J; Kranias E G
Inotropic responses to isoproterenol and phosphodiesterase inhibitors in intact guinea pig hearts: comparison of cyclic AMP levels and phosphorylation of sarcoplasmic reticulum and myofibrillar proteins.
Circulation research 1989;64(1):104-11.
-
1989: Young E F; McKee M J; Ferguson D G; Kranias E G
Structural characterization of phospholamban in cardiac sarcoplasmic reticulum membranes by cross-linking.
Membrane biochemistry 1989;8(2):95-106.
-
1988: Kranias E G; Steenaart N A; Di Salvo J
Purification and characterization of phospholamban phosphatase from cardiac muscle.
The Journal of biological chemistry 1988;263(30):15681-7.
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1988: Ferguson D G; Young E F; Raeymaekers L; Kranias E G
Localization of phospholamban in smooth muscle using immunogold electron microscopy.
The Journal of cell biology 1988;107(2):555-62.
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1988: Kranias E G; Gupta R C; Jakab G; Kim H W; Steenaart N A; Rapundalo S T
The role of protein kinases and protein phosphatases in the regulation of cardiac sarcoplasmic reticulum function.
Molecular and cellular biochemistry 1988;82(1-2):37-44.
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1988: Jakab G; Kranias E G
Phosphorylation and dephosphorylation of purified phospholamban and associated phosphatidylinositides.
Biochemistry 1988;27(10):3799-806.
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1988: Jakab G; Rapundalo S T; Solaro R J; Kranias E G
Phosphorylation of phospholipids in isolated guinea pig hearts stimulated with isoprenaline.
The Biochemical journal 1988;251(1):189-94.
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1988: Garvey J L; Kranias E G; Solaro R J
Phosphorylation of C-protein, troponin I and phospholamban in isolated rabbit hearts.
The Biochemical journal 1988;249(3):709-14.
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1987: Kim H W; Kim D H; Ikemoto N; Kranias E G
Lack of effects of calcium X calmodulin-dependent phosphorylation on Ca2+ release from cardiac sarcoplasmic reticulum.
Biochimica et biophysica acta 1987;903(2):333-40.
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1987: Gupta R C; Davis B A; Kranias E G
Mechanism of the stimulation of cardiac sarcoplasmic reticulum calcium pump by calmodulin.
Membrane biochemistry 1987;7(2):73-86.
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1987: Edes I; Kranias E G
Regulation of cardiac sarcoplasmic reticulum function by phospholamban.
Membrane biochemistry 1987;7(3):175-92.
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1985: Kranias E G; Garvey J L; Srivastava R D; Solaro R J
Phosphorylation and functional modifications of sarcoplasmic reticulum and myofibrils in isolated rabbit hearts stimulated with isoprenaline.
The Biochemical journal 1985;226(1):113-21.
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