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Luise Krauth-Siegel

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Chemicals & Drugs

Phenomena

Oxidation-Reduction

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Genes & Molecular Sequences

Amino Acid Sequences

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Tolga Eichhorn; Martin Frank; Corinna Hiller; Kerstin Hirschfelder; R Luise Krauth-Siegel; Rolf Mertens; Rolf Müller; Thomas Efferth
Identification by high-throughput in silico screening of radio-protecting compounds targeting the DNA-binding domain of the tumor suppressor p53.
Tolga Eichhorn; Martin Frank; Joachim Granzin; R Luise Krauth-Siegel; Wolf-Dieter Lehmann; Rolf Mertens; Thomas Simmet; Dominic Winter; Berthold Büchele; Natalie Dirdjaja; Thomas Efferth
Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum.
Federica Lizzi; Almudena López-Sánchez; Luis Rivas; Giacomo Veronesi; Reto Brun; Dennis G Hall; Marcel Kaiser; R Luise Krauth-Siegel; Federica Belluti; Christian Bergamini; Maria Laura Bolognesi
Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile.

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2013: Tolga Eichhorn; Martin Frank; Corinna Hiller; Kerstin Hirschfelder; R Luise Krauth-Siegel; Rolf Mertens; Rolf Müller; Thomas Efferth
Identification by high-throughput in silico screening of radio-protecting compounds targeting the DNA-binding domain of the tumor suppressor p53.
Cancer genomics & proteomics 2013;10(1):35-45.
2013: Tolga Eichhorn; Martin Frank; Joachim Granzin; R Luise Krauth-Siegel; Wolf-Dieter Lehmann; Rolf Mertens; Thomas Simmet; Dominic Winter; Berthold Büchele; Natalie Dirdjaja; Thomas Efferth
Molecular interaction of artemisinin with translationally controlled tumor protein (TCTP) of Plasmodium falciparum.
Biochemical pharmacology 2013;85(1):38-45.
2012: Federica Lizzi; Almudena López-Sánchez; Luis Rivas; Giacomo Veronesi; Reto Brun; Dennis G Hall; Marcel Kaiser; R Luise Krauth-Siegel; Federica Belluti; Christian Bergamini; Maria Laura Bolognesi
Conjugation of quinones with natural polyamines: toward an expanded antitrypanosomatid profile.
Journal of medicinal chemistry 2012;55(23):10490-500.
2012: R Luise Krauth-Siegel; Alejandro E Leroux
Low-molecular-mass antioxidants in parasites.
Antioxidants & redox signaling 2012;17(4):583-607.
2012: Florian Fueller; Britta Jehle; Joe D Lewis; Kerstin Putzker; R Luise Krauth-Siegel
High throughput screening against the peroxidase cascade of African trypanosomes identifies antiparasitic compounds that inactivate tryparedoxin.
The Journal of biological chemistry 2012;287(12):8792-802.
2011: Endalkachew Nibret; R Luise Krauth-Siegel; Mahamoud Youns; Michael Wink
Biological activities of xanthatin from Xanthium strumarium leaves.
Phytotherapy research : PTR 2011;25(12):1883-90.
2011: Angela Roldán; Marcelo A Comini; Martina Crispo; R Luise Krauth-Siegel
Lipoamide dehydrogenase is essential for both bloodstream and procyclic Trypanosoma brucei.
Molecular microbiology 2011;81(3):623-39.
2011: Christian Eberle; Birgit Sophia Lauber; Daniel Fankhauser; Marcel Kaiser; Reto Brun; R Luise Krauth-Siegel; François Diederich
Improved inhibitors of trypanothione reductase by combination of motifs: synthesis, inhibitory potency, binding mode, and antiprotozoal activities.
ChemMedChem 2011;6(2):292-301.
2010: Sevgi Ceylan; Vera Seidel; Nicole Ziebart; Carsten Berndt; Natalie Dirdjaja; R Luise Krauth-Siegel
The dithiol glutaredoxins of african trypanosomes have distinct roles and are closely linked to the unique trypanothione metabolism.
The Journal of biological chemistry 2010;285(45):35224-37.
2010: Barbara M Bakker; R Luise Krauth-Siegel; Christine Clayton; Keith Matthews; Mark Girolami; Hans V Westerhoff; Paul A M Michels; Rainer Breitling; Michael P Barrett
The silicon trypanosome.
Parasitology 2010;137(9):1333-41.
2010: Claudia Muhle-Goll; Florian Füller; Anne S Ulrich; R Luise Krauth-Siegel
The conserved Cys76 plays a crucial role for the conformation of reduced glutathione peroxidase-type tryparedoxin peroxidase.
FEBS letters 2010;584(5):1027-32.
2009: Christian Eberle; Johannes A Burkhard; Bernhard Stump; Marcel Kaiser; Reto Brun; R Luise Krauth-Siegel; François Diederich
Synthesis, inhibition potency, binding mode, and antiprotozoal activities of fluorescent inhibitors of trypanothione reductase based on mepacrine-conjugated diaryl sulfide scaffolds.
ChemMedChem 2009;4(12):2034-44.
2009: Marcelo A Comini; Natalie Dirdjaja; Mariel Kaschel; R Luise Krauth-Siegel
Preparative enzymatic synthesis of trypanothione and trypanothione analogues.
International journal for parasitology 2009;39(10):1059-62.
2009: I Nicole Wenzel; Pui E Wong; Louis Maes; Thomas J J Müller; R Luise Krauth-Siegel; Michael P Barrett; Elisabeth Davioud
Unsaturated Mannich bases active against multidrug-resistant Trypanosoma brucei brucei strains.
ChemMedChem 2009;4(3):339-51.
2009: Bernhard Stump; Christian Eberle; W Bernd Schweizer; Marcel Kaiser; Reto Brun; R Luise Krauth-Siegel; Dieter Lentz; François Diederich
Pentafluorosulfanyl as a novel building block for enzyme inhibitors: trypanothione reductase inhibition and antiprotozoal activities of diarylamines.
Chembiochem : a European journal of chemical biology 2009;10(1):79-83.
2009: Alexandra Wendler; Thorsten Irsch; Naila Rabbani; Paul J Thornalley; R Luise Krauth-Siegel
Glyoxalase II does not support methylglyoxal detoxification but serves as a general trypanothione thioesterase in African trypanosomes.
Molecular and biochemical parasitology 2009;163(1):19-27.
2008: Bernhard Stump; Christian Eberle; Marcel Kaiser; Reto Brun; R Luise Krauth-Siegel; François Diederich
Diaryl sulfide-based inhibitors of trypanothione reductase: inhibition potency, revised binding mode and antiprotozoal activities.
Organic & biomolecular chemistry 2008;6(21):3935-47.
2008: R Luise Krauth-Siegel; Marcelo A Comini
Redox control in trypanosomatids, parasitic protozoa with trypanothione-based thiol metabolism.
Biochimica et biophysica acta 2008;1780(11):1236-48.
2008: Johannes Melchers; Michael Diechtierow; Krisztina Feher; Irmgard Sinning; Ivo Tews; R Luise Krauth-Siegel; Claudia Muhle-Goll
Structural basis for a distinct catalytic mechanism in Trypanosoma brucei tryparedoxin peroxidase.
The Journal of biological chemistry 2008;283(44):30401-11.
2008: Marcelo A Comini; Jochen Rettig; Natalie Dirdjaja; Eva-Maria Hanschmann; Carsten Berndt; R Luise Krauth-Siegel
Monothiol glutaredoxin-1 is an essential iron-sulfur protein in the mitochondrion of African trypanosomes.
The Journal of biological chemistry 2008;283(41):27785-98.
2008: Kathrin Buchholz; Marcelo A Comini; Dirk Wissenbach; R Heiner Schirmer; R Luise Krauth-Siegel; Stephan Gromer
Cytotoxic interactions of methylene blue with trypanosomatid-specific disulfide reductases and their dithiol products.
Molecular and biochemical parasitology 2008;160(1):65-9.
2008: Michael Filser; Marcelo A Comini; Maria M Molina-Navarro; Natalie Dirdjaja; Enrique Herrero; R Luise Krauth-Siegel
Cloning, functional analysis, and mitochondrial localization of Trypanosoma brucei monothiol glutaredoxin-1.
Biological chemistry 2008;389(1):21-32.
2007: Bernhard Stump; Marcel Kaiser; Reto Brun; R Luise Krauth-Siegel; François Diederich
Betraying the parasite's redox system: diaryl sulfide-based inhibitors of trypanothione reductase: subversive substrates and antitrypanosomal properties.
ChemMedChem 2007;2(12):1708-12.
2007: Williams Porcal; Paola Hernández; Mariana Boiani; Gabriela Aguirre; Lucía Boiani; Agustina Chidichimo; Juan J Cazzulo; Nuria E Campillo; Juan A Paez; Ana Castro; R Luise Krauth-Siegel; Carolina Davies; Miguel A Basombrío; Mercedes González; Hugo Cerecetto
In vivo anti-Chagas vinylthio-, vinylsulfinyl-, and vinylsulfonylbenzofuroxan derivatives.
Journal of medicinal chemistry 2007;50(24):6004-15.
2007: Tanja Schlecker; Marcelo A Comini; Johannes Melchers; Thomas Ruppert; R Luise Krauth-Siegel
Catalytic mechanism of the glutathione peroxidase-type tryparedoxin peroxidase of Trypanosoma brucei.
The Biochemical journal 2007;405(3):445-54.
2007: Johannes Melchers; Natalie Dirdjaja; Thomas Ruppert; R Luise Krauth-Siegel
Glutathionylation of trypanosomal thiol redox proteins.
The Journal of biological chemistry 2007;282(12):8678-94.
2007: Marcelo A Comini; R Luise Krauth-Siegel; Leopold Flohé
Depletion of the thioredoxin homologue tryparedoxin impairs antioxidative defence in African trypanosomes.
The Biochemical journal 2007;402(1):43-9.
2006: Lucía Otero; Marisol Vieites; Lucía Boiani; Ana Denicola; Carolina Rigol; Lucía Opazo; Claudio Olea-Azar; Juan Diego Maya; Antonio Morello; R Luise Krauth-Siegel; Oscar E Piro; Eduardo E Castellano; Mercedes González; Dinorah Gambino; Hugo Cerecetto
Novel antitrypanosomal agents based on palladium nitrofurylthiosemicarbazone complexes: DNA and redox metabolism as potential therapeutic targets.
Journal of medicinal chemistry 2006;49(11):3322-31.
2005: Brittany Lee; Holger Bauer; Johannes Melchers; Thomas Ruppert; Lauren Rattray; Vanessa Yardley; Elisabeth Davioud; R Luise Krauth-Siegel
Irreversible inactivation of trypanothione reductase by unsaturated Mannich bases: a divinyl ketone as key intermediate.
Journal of medicinal chemistry 2005;48(23):7400-10.
2005: Svea Meiering; Oliver Inhoff; Jan Mies; Adam Vincek; Gabriel Garcia; Bernd Kramer; Matthias Dormeyer; R Luise Krauth-Siegel
Inhibitors of Trypanosoma cruzi trypanothione reductase revealed by virtual screening and parallel synthesis.
Journal of medicinal chemistry 2005;48(15):4793-802.
2005: Christof Werner; Milton T Stubbs; R Luise Krauth-Siegel; Gerhard Klebe
The crystal structure of Plasmodium falciparum glutamate dehydrogenase, a putative target for novel antimalarial drugs.
Journal of molecular biology 2005;349(3):597-607.
2005: Tanja Schlecker; Armin Schmidt; Natalie Dirdjaja; Frank Voncken; Christine Clayton; R Luise Krauth-Siegel
Substrate specificity, localization, and essential role of the glutathione peroxidase-type tryparedoxin peroxidases in Trypanosoma brucei.
The Journal of biological chemistry 2005;280(15):14385-94.
2005: R Luise Krauth-Siegel; Holger Bauer; R Heiner Schirmer
Dithiol proteins as guardians of the intracellular redox milieu in parasites: old and new drug targets in trypanosomes and malaria-causing plasmodia.
Angewandte Chemie (International ed. in English) 2005;44(5):690-715.
2004: Thorsten Irsch; R Luise Krauth-Siegel
Glyoxalase II of African trypanosomes is trypanothione-dependent.
The Journal of biological chemistry 2004;279(21):22209-17.
2003: Heide Schmidt; R Luise Krauth-Siegel
Functional and physicochemical characterization of the thioredoxin system in Trypanosoma brucei.
The Journal of biological chemistry 2003;278(47):46329-36.
2003: Rosmarie Friemann; Heide Schmidt; S Ramaswamy; Michael Forstner; R Luise Krauth-Siegel; Hans Eklund
Structure of thioredoxin from Trypanosoma brucei brucei.
FEBS letters 2003;554(3):301-5.
2003: Sylke Müller; Eva Liebau; Rolf D Walter; R Luise Krauth-Siegel
Thiol-based redox metabolism of protozoan parasites.
Trends in parasitology 2003;19(7):320-8.
2003: R Luise Krauth-Siegel; Oliver Inhoff
Parasite-specific trypanothione reductase as a drug target molecule.
Parasitology research 2003;90 Suppl 2():S77-85.
2003: R Luise Krauth-Siegel; Svea K Meiering; Heide Schmidt
The parasite-specific trypanothione metabolism of trypanosoma and leishmania.
Biological chemistry 2003;384(4):539-49.
2003: José Gutiérrez-Correa; R Luise Krauth-Siegel; Andrés O M Stoppani
Phenothiazine radicals inactivate Trypanosoma cruzi dihydrolipoamide dehydrogenase: enzyme protection by radical scavengers.
Free radical research 2003;37(3):281-91.
2003: Henning Hillebrand; Armin Schmidt; R Luise Krauth-Siegel
A second class of peroxidases linked to the trypanothione metabolism.
The Journal of biological chemistry 2003;278(9):6809-15.
2002: Armin Schmidt; Christine E Clayton; R Luise Krauth-Siegel
Silencing of the thioredoxin gene in Trypanosoma brucei brucei.
Molecular and biochemical parasitology 2002;125(1-2):207-10.
2002: Armin Schmidt; R Luise Krauth-Siegel
Enzymes of the trypanothione metabolism as targets for antitrypanosomal drug development.
Current topics in medicinal chemistry 2002;2(11):1239-59.
2002: Oliver Inhoff; Jonathan M Richards; Jan Willem Brîet; Gordon Lowe; R Luise Krauth-Siegel
Coupling of a competitive and an irreversible ligand generates mixed type inhibitors of Trypanosoma cruzi trypanothione reductase.
Journal of medicinal chemistry 2002;45(20):4524-30.
2002: Nina Reckenfelderbäumer; R Luise Krauth-Siegel
Catalytic properties, thiol pK value, and redox potential of Trypanosoma brucei tryparedoxin.
The Journal of biological chemistry 2002;277(20):17548-55.
2002: Tanja Breidbach; Stefan Scory; R Luise Krauth-Siegel; Dietmar Steverding
Growth inhibition of bloodstream forms of Trypanosoma brucei by the iron chelator deferoxamine.
International journal for parasitology 2002;32(4):473-9.
2002: Sanjay K Shahi; R Luise Krauth-Siegel; Christine E Clayton
Overexpression of the putative thiol conjugate transporter TbMRPA causes melarsoprol resistance in Trypanosoma brucei.
Molecular microbiology 2002;43(5):1129-38.
2002: R Luise Krauth-Siegel; Heide Schmidt
Trypanothione and tryparedoxin in ribonucleotide reduction.
Methods in enzymology 2002;347():259-66.
2001: Matthias Dormeyer; Nina Reckenfelderbäumer; H Ludemann; R Luise Krauth-Siegel
Trypanothione-dependent synthesis of deoxyribonucleotides by Trypanosoma brucei ribonucleotide reductase.
The Journal of biological chemistry 2001;276(14):10602-6.
2001: L Salmon-Chemin; E Buisine; Vanessa Yardley; S Kohler; MA Debreu; Valérie Landry; Christian Sergheraert; S L Croft; R Luise Krauth-Siegel; Elisabeth Davioud
2- and 3-substituted 1,4-naphthoquinone derivatives as subversive substrates of trypanothione reductase and lipoamide dehydrogenase from Trypanosoma cruzi: synthesis and correlation between redox cycling activities and in vitro cytotoxicity.
Journal of medicinal chemistry 2001;44(4):548-65.
2000: S Bonse; J M Richards; S A Ross; G Lowe; R Luise Krauth-Siegel
(2,2':6',2"-Terpyridine)platinum(II) complexes are irreversible inhibitors of Trypanosoma cruzi trypanothione reductase but not of human glutathione reductase.
Journal of medicinal chemistry 2000;43(25):4812-21.
2000: José Gutiérrez-Correa; R Luise Krauth-Siegel; Andrés O M Stoppani
Inactivation of Trypanosoma cruzi dihydrolipoamide dehydrogenase by leukocyte myeloperoxidase systems: role of hypochloride and nitrite related radicals.
Revista Argentina de microbiología 2000;32(3):136-43.
2000: J Gutierrez-Correa; R Luise Krauth-Siegel; Andrés O M Stoppani
Trypanosoma cruzi dihydrolipoamide dehydrogenase is inactivated by myeloperoxidase-generated "reactive species".
Free radical research 2000;33(1):13-22.
2000: Tanja Breidbach; R Luise Krauth-Siegel; Dietmar Steverding
Ribonucleotide reductase is regulated via the R2 subunit during the life cycle of Trypanosoma brucei.
FEBS letters 2000;473(2):212-6.
2000: Nina Reckenfelderbäumer; H Lüdemann; Heide Schmidt; Dietmar Steverding; R Luise Krauth-Siegel
Identification and functional characterization of thioredoxin from Trypanosoma brucei brucei.
The Journal of biological chemistry 2000;275(11):7547-52.
2000: S Krieger; W Schwarz; Mark R Ariyanayagam; Alan H Fairlamb; R Luise Krauth-Siegel; Christine Clayton
Trypanosomes lacking trypanothione reductase are avirulent and show increased sensitivity to oxidative stress.
Molecular microbiology 2000;35(3):542-52.
1999: S Bonse; Christiane Santelli-Rouvier; Jacques Barbe; R Luise Krauth-Siegel
Inhibition of Trypanosoma cruzi trypanothione reductase by acridines: kinetic studies and structure-activity relationships.
Journal of medicinal chemistry 1999;42(26):5448-54.
1999: Klaus Blumenstiel; R Schöneck; Vanessa Yardley; S L Croft; R Luise Krauth-Siegel
Nitrofuran drugs as common subversive substrates of Trypanosoma cruzi lipoamide dehydrogenase and trypanothione reductase.
Biochemical pharmacology 1999;58(11):1791-9.
1999: R Luise Krauth-Siegel; G H Coombs
Enzymes of parasite thiol metabolism as drug targets.
Parasitology today (Personal ed.) 1999;15(10):404-9.
1999: H Gallwitz; S Bonse; A Martinez-Cruz; Ilme Schlichting; K Schumacher; R Luise Krauth-Siegel
Ajoene is an inhibitor and subversive substrate of human glutathione reductase and Trypanosoma cruzi trypanothione reductase: crystallographic, kinetic, and spectroscopic studies.
Journal of medicinal chemistry 1999;42(3):364-72.
1998: J T Wagner; H Lüdemann; P M Färber; F Lottspeich; R Luise Krauth-Siegel
Glutamate dehydrogenase, the marker protein of Plasmodium falciparum--cloning, expression and characterization of the malarial enzyme.
European journal of biochemistry / FEBS 1998;258(2):813-9.
1998: R Luise Krauth-Siegel; L David Arscott; A Schönleben-Janas; R Heiner Schirmer; Charles H Williams
Role of active site tyrosine residues in catalysis by human glutathione reductase.
Biochemistry 1998;37(40):13968-77.
1998: H Lüdemann; Matthias Dormeyer; C Sticherling; D Stallmann; H Follmann; R Luise Krauth-Siegel
Trypanosoma brucei tryparedoxin, a thioredoxin-like protein in African trypanosomes.
FEBS letters 1998;431(3):381-5.
1997: Matthias Dormeyer; R Schöneck; G A Dittmar; R Luise Krauth-Siegel
Cloning, sequencing and expression of ribonucleotide reductase R2 from Trypanosoma brucei.
FEBS letters 1997;414(2):449-53.
1997: R Schöneck; O Billaut-Mulot; P Numrich; M A Ouaissi; R Luise Krauth-Siegel
Cloning, sequencing and functional expression of dihydrolipoamide dehydrogenase from the human pathogen Trypanosoma cruzi.
European journal of biochemistry / FEBS 1997;243(3):739-47.
1996: R Luise Krauth-Siegel; H Lüdemann
Reduction of dehydroascorbate by trypanothione.
Molecular and biochemical parasitology 1996;80(2):203-8.
1996: C H Faerman; S N Savvides; C Strickland; M A Breidenbach; J A Ponasik; B Ganem; Daniel R Ripoll; R Luise Krauth-Siegel; P Andrew Karplus
Charge is the major discriminating factor for glutathione reductase versus trypanothione reductase inhibitors.
Bioorganic & medicinal chemistry 1996;4(8):1247-53.
1996: A Schönleben-Janas; P Kirsch; P R Mittl; R Heiner Schirmer; R Luise Krauth-Siegel
Inhibition of human glutathione reductase by 10-arylisoalloxazines: crystalline, kinetic, and electrochemical studies.
Journal of medicinal chemistry 1996;39(7):1549-54.
1996: R Luise Krauth-Siegel; J G Müller; F Lottspeich; R Heiner Schirmer
Glutathione reductase and glutamate dehydrogenase of Plasmodium falciparum, the causative agent of tropical malaria.
European journal of biochemistry / FEBS 1996;235(1-2):345-50.
1996: E M Jacoby; Ilme Schlichting; C B Lantwin; W Kabsch; R Luise Krauth-Siegel
Crystal structure of the Trypanosoma cruzi trypanothione reductase.mepacrine complex.
Proteins 1996;24(1):73-80.
1995: R Luise Krauth-Siegel; R Schöneck
Flavoprotein structure and mechanism. 5. Trypanothione reductase and lipoamide dehydrogenase as targets for a structure-based drug design.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(12):1138-46.
1995: R Luise Krauth-Siegel; E M Jacoby; R Heiner Schirmer
Trypanothione and N1-glutathionylspermidine: isolation and determination.
Methods in enzymology 1995;251():287-94.
1994: C B Lantwin; Ilme Schlichting; W Kabsch; Emil F Pai; R Luise Krauth-Siegel
The structure of Trypanosoma cruzi trypanothione reductase in the oxidized and NADPH reduced state.
Proteins 1994;18(2):161-73.
1993: J G Müller; U S Bücheler; K Kayser; R Heiner Schirmer; D Werner; R Luise Krauth-Siegel
Glutathione reductase in human and murine lung tumors: high levels of mRNA and enzymatic activity.
Cellular and molecular biology (Noisy-le-Grand, France) 1993;39(4):389-96.
1993: R Luise Krauth-Siegel; C Sticherling; I Jöst; C T Walsh; Emil F Pai; W Kabsch; C B Lantwin
Crystallization and preliminary crystallographic analysis of trypanothione reductase from Trypanosoma cruzi, the causative agent of Chagas' disease.
FEBS letters 1993;317(1-2):105-8.
1990: H Lohrer; R Luise Krauth-Siegel
Purification and characterization of lipoamide dehydrogenase from Trypanosoma cruzi.
European journal of biochemistry / FEBS 1990;194(3):863-9.
1989: R Luise Krauth-Siegel; M C Jockers-Scherübl; Katja Becker; R Heiner Schirmer
NADPH-dependent disulphide reductases.
Biochemical Society transactions 1989;17(2):315-7.
1989: M C Jockers-Scherübl; R Heiner Schirmer; R Luise Krauth-Siegel
Trypanothione reductase from Trypanosoma cruzi. Catalytic properties of the enzyme and inhibition studies with trypanocidal compounds.
European journal of biochemistry / FEBS 1989;180(2):267-72.
1988: P Andrew Karplus; R Luise Krauth-Siegel; R Heiner Schirmer; Georg E Schulz
Inhibition of human glutathione reductase by the nitrosourea drugs 1,3-bis(2-chloroethyl)-1-nitrosourea and 1-(2-chloroethyl)-3-(2-hydroxyethyl)-1-nitrosourea. A crystallographic analysis.
European journal of biochemistry / FEBS 1988;171(1-2):193-8.
1987: R Luise Krauth-Siegel; B Enders; G B Henderson; Alan H Fairlamb; R Heiner Schirmer
Trypanothione reductase from Trypanosoma cruzi. Purification and characterization of the crystalline enzyme.
European journal of biochemistry / FEBS 1987;164(1):123-8.
1987: R Heiner Schirmer; T Schöllhammer; G Eisenbrand; R Luise Krauth-Siegel
Oxidative stress as a defense mechanism against parasitic infections.
Free radical research communications 1987;3(1-5):3-12.
1987: W Stahl; R Luise Krauth-Siegel; R Heiner Schirmer; Gerhard Eisenbrand
A method to determine the carbamoylating potential of 1-(2-chloroethyl)-1-nitrosoureas.
IARC scientific publications 1987;(84):191-3.
1986: R Frank; M Trosin; A G Tomasselli; L Noda; R Luise Krauth-Siegel; R Heiner Schirmer
Mitochondrial adenylate kinase (AK2) from bovine heart. The complete primary structure.
European journal of biochemistry / FEBS 1986;154(1):205-11.
1985: R Luise Krauth-Siegel; R Heiner Schirmer; S Ghisla
FAD analogues as prosthetic groups of human glutathione reductase. Properties of the modified enzyme species and comparisons with the active site structure.
European journal of biochemistry / FEBS 1985;148(2):335-44.
1984: M Bilzer; R Luise Krauth-Siegel; R Heiner Schirmer; T P Akerboom; H Sies; G E Schulz
Interaction of a glutathione S-conjugate with glutathione reductase. Kinetic and X-ray crystallographic studies.
European journal of biochemistry / FEBS 1984;138(2):373-8.
1982: R Luise Krauth-Siegel; R Blatterspiel; M Saleh; E Schiltz; R Heiner Schirmer; R Untucht-Grau
Glutathione reductase from human erythrocytes. The sequences of the NADPH domain and of the interface domain.
European journal of biochemistry / FEBS 1982;121(2):259-67.
1981: R Untucht-Grau; R Heiner Schirmer; I Schirmer; R Luise Krauth-Siegel
Glutathione reductase from human erythrocytes: amino-acid sequence of the structurally known FAD-binding domain.
European journal of biochemistry / FEBS 1981;120(2):407-19.