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Barbara Kream

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TOP 3
Maobin Yang; Lorin B Trettel; Douglas J Adams; John R Harrison; Ernesto Canalis; Barbara E Kream
Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation.
Tripti Gaur; Sadiq Hussain; Rajini Mudhasani; Isha Parulkar; Jennifer L Colby; Dana Frederick; Barbara E Kream; Andre J van Wijnen; Janet L Stein; Gary S Stein; Stephen N Jones; Jane B Lian
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.
Hechang Huang; Daichi Chikazu; Olga S Voznesensky; Harvey R Herschman; Barbara E Kream; Hicham Drissi; Carol Pilbeam
Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.

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All Publications

2010: Maobin Yang; Lorin B Trettel; Douglas J Adams; John R Harrison; Ernesto Canalis; Barbara E Kream
Col3.6-HSD2 transgenic mice: a glucocorticoid loss-of-function model spanning early and late osteoblast differentiation.
Bone 2010;47(3):573-82.
2010: Tripti Gaur; Sadiq Hussain; Rajini Mudhasani; Isha Parulkar; Jennifer L Colby; Dana Frederick; Barbara E Kream; Andre J van Wijnen; Janet L Stein; Gary S Stein; Stephen N Jones; Jane B Lian
Dicer inactivation in osteoprogenitor cells compromises fetal survival and bone formation, while excision in differentiated osteoblasts increases bone mass in the adult mouse.
Developmental biology 2010;340(1):10-21.
2010: Hechang Huang; Daichi Chikazu; Olga S Voznesensky; Harvey R Herschman; Barbara E Kream; Hicham Drissi; Carol Pilbeam
Parathyroid hormone induction of cyclooxygenase-2 in murine osteoblasts: role of the calcium-calcineurin-NFAT pathway.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2010;25(4):819-29.
2008: Taranpreet K Chandhoke; Yu-Feng Huang; Fei Liu; Gloria A Gronowicz; Douglas J Adams; John R Harrison; Barbara E Kream
Osteopenia in transgenic mice with osteoblast-targeted expression of the inducible cAMP early repressor.
Bone 2008;43(1):101-9.
2008: Maobin Yang; Barbara E Kream
Calcitonin induces expression of the inducible cAMP early repressor in osteoclasts.
Endocrine 2008;33(3):245-53.
2007: Fei Liu; Sun-Kyeong Lee; Douglas J Adams; Gloria A Gronowicz; Barbara E Kream
CREM deficiency in mice alters the response of bone to intermittent parathyroid hormone treatment.
Bone 2007;40(4):1135-43.
2007: Amanda J Notini; Julie F McManus; Alison Moore; Mary L Bouxsein; Mark Jimenez; W S Maria Chiu; Vaida Glatt; Barbara E Kream; David J Handelsman; Howard A Morris; Jeffrey D Zajac; Rachel A Davey
Osteoblast deletion of exon 3 of the androgen receptor gene results in trabecular bone loss in adult male mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2007;22(3):347-56.
2007: Rebecca L Cochrane; Stephen H Clark; Adam Harris; Barbara E Kream
Rearrangement of a conditional allele regardless of inheritance of a Cre recombinase transgene.
Genesis (New York, N.Y. : 2000) 2007;45(1):17-20.
2006: Jin Jiang; Alexander C Lichtler; Gloria A Gronowicz; Douglas J Adams; Stephen H Clark; Clifford J Rosen; Barbara E Kream
Transgenic mice with osteoblast-targeted insulin-like growth factor-I show increased bone remodeling.
Bone 2006;39(3):494-504.
2006: L B Sher; John R Harrison; Douglas J Adams; Barbara E Kream
Impaired cortical bone acquisition and osteoblast differentiation in mice with osteoblast-targeted disruption of glucocorticoid signaling.
Calcified tissue international 2006;79(2):118-25.
2006: Krista M Delahunty; Kathryn L Shultz; Gloria A Gronowicz; Boguslawa Koczon-Jaremko; Martin Adamo; Lindsay G Horton; Joseph Lorenzo; Leah Rae Donahue; Cheryl L Ackert-Bicknell; Barbara E Kream; Wesley G Beamer; Clifford J Rosen
Congenic mice provide in vivo evidence for a genetic locus that modulates serum insulin-like growth factor-I and bone acquisition.
Endocrinology 2006;147(8):3915-23.
2006: Ante Ivkosić; Mark S Kronenberg; Alexander C Lichtler; Barbara E Kream
Analysis of internal deletions of a rat Col1a1 promoter fragment in transfected ROS17/2.8 cells.
Collegium antropologicum 2006;30(2):401-4.
2006: Jianing He; Clifford J Rosen; Douglas J Adams; Barbara E Kream
Postnatal growth and bone mass in mice with IGF-I haploinsufficiency.
Bone 2006;38(6):826-35.
2006: Christopher J Lengner; Heather A Steinman; James Gagnon; Thomas W Smith; Janet E Henderson; Barbara E Kream; Gary S Stein; Jane B Lian; Stephen N Jones
Osteoblast differentiation and skeletal development are regulated by Mdm2-p53 signaling.
The Journal of cell biology 2006;172(6):909-21.
2005: F Liu; Y-F Huang; Barbara E Kream
Identification of novel cAMP responsive element modulator (CREM) isoforms expressed by osteoblasts.
Calcified tissue international 2005;77(2):91-5.
2004: Fei Liu; Henning W Woitge; Alen Braut; Mark S Kronenberg; Alexander C Lichtler; Mina Mina; Barbara E Kream
Expression and activity of osteoblast-targeted Cre recombinase transgenes in murine skeletal tissues.
The International journal of developmental biology 2004;48(7):645-53.
2004: Lorin B Sher; Henning W Woitge; Douglas J Adams; Gloria A Gronowicz; Zygmunt Krozowski; John R Harrison; Barbara E Kream
Transgenic expression of 11beta-hydroxysteroid dehydrogenase type 2 in osteoblasts reveals an anabolic role for endogenous glucocorticoids in bone.
Endocrinology 2004;145(2):922-9.
2003: Jeanne M Nervina; Sotirios Tetradis; Y-F Huang; D Harrison; C Molina; Barbara E Kream
Expression of inducible cAMP early repressor is coupled to the cAMP-protein kinase A signaling pathway in osteoblasts.
Bone 2003;32(5):483-90.
2002: John R Harrison; Henning W Woitge; Barbara E Kream
Genetic approaches to determine the role of glucocorticoid signaling in osteoblasts.
Endocrine 2002;17(1):37-42.
2001: Henning W Woitge; J Harrison; A Ivkosic; Z Krozowski; Barbara E Kream
Cloning and in vitro characterization of alpha 1(I)-collagen 11 beta-hydroxysteroid dehydrogenase type 2 transgenes as models for osteoblast-selective inactivation of natural glucocorticoids.
Endocrinology 2001;142(3):1341-8.
2000: Henning W Woitge; Barbara E Kream
Calvariae from fetal mice with a disrupted Igf1 gene have reduced rates of collagen synthesis but maintain responsiveness to glucocorticoids.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 2000;15(10):1956-64.
2000: Z Bogdanovic; Y F Huang; Milan Dodig; Stephen H Clark; Alexander C Lichtler; Barbara E Kream
Parathyroid hormone inhibits collagen synthesis and the activity of rat col1a1 transgenes mainly by a cAMP-mediated pathway in mouse calvariae.
Journal of cellular biochemistry 2000;77(1):149-58.
1999: Marja M Hurley; Sotirios Tetradis; Y F Huang; Janet Hock; Barbara E Kream; Lawrence G Raisz; Maria Giovanna Sabbieti
Parathyroid hormone regulates the expression of fibroblast growth factor-2 mRNA and fibroblast growth factor receptor mRNA in osteoblastic cells.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1999;14(5):776-83.
1998: Sotirios Tetradis; Jeanne M Nervina; K Nemoto; Barbara E Kream
Parathyroid hormone induces expression of the inducible cAMP early repressor in osteoblastic MC3T3-E1 cells and mouse calvariae.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(12):1846-51.
1998: Yu-Feng Huang; John R Harrison; J A Lorenzo; Barbara E Kream
Parathyroid hormone induces interleukin-6 heterogeneous nuclear and messenger RNA expression in murine calvarial organ cultures.
Bone 1998;23(4):327-32.
1998: A Bedalov; Roberto Salvatori; Milan Dodig; B Kapural; D Pavlin; Barbara E Kream; Stephen H Clark; C O Woody; David W Rowe; Alexander C Lichtler
1,25-Dihydroxyvitamin D3 inhibition of col1a1 promoter expression in calvariae from neonatal transgenic mice.
Biochimica et biophysica acta 1998;1398(3):285-93.
1998: John R Harrison; L M Kleinert; Penny L Kelly; Paul H Krebsbach; C Woody; S Clark; David W Rowe; Alexander C Lichtler; Barbara E Kream
Interleukin-1 represses COLIA1 promoter activity in calvarial bones of transgenic ColCAT mice in vitro and in vivo.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1998;13(7):1076-83.
1997: Sotirios Tetradis; Carol Pilbeam; Y Liu; Harvey R Herschman; Barbara E Kream
Parathyroid hormone increases prostaglandin G/H synthase-2 transcription by a cyclic adenosine 3',5'-monophosphate-mediated pathway in murine osteoblastic MC3T3-E1 cells.
Endocrinology 1997;138(9):3594-600.
1997: Barbara E Kream; Sotirios Tetradis; D Lafrancis; P M Fall; J H Feyen; Lawrence G Raisz
Modulation of the effects of glucocorticoids on collagen synthesis in fetal rat calvariae by insulin-like growth factor binding protein-2.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1997;12(6):889-95.
1997: S Advani; D LaFrancis; E Bogdanovic; Pamela Taxel; Lawrence G Raisz; Barbara E Kream
Dexamethasone suppresses in vivo levels of bone collagen synthesis in neonatal mice.
Bone 1997;20(1):41-6.
1996: Sotirios Tetradis; Carol Pilbeam; Y Liu; Barbara E Kream
Parathyroid hormone induces prostaglandin G/H synthase-2 expression by a cyclic adenosine 3',5'-monophosphate-mediated pathway in the murine osteoblastic cell line MC3T3-E1.
Endocrinology 1996;137(12):5435-40.
1996: M Dodig; M S Kronenberg; A Bedalov; Barbara E Kream; G Gronowicz; S H Clark; K Mack; Y H Liu; R Maxon; Z Z Pan; William B Upholt; David W Rowe; Alexander C Lichtler
Identification of a TAAT-containing motif required for high level expression of the COL1A1 promoter in differentiated osteoblasts of transgenic mice.
The Journal of biological chemistry 1996;271(27):16422-9.
1995: A Bedalov; Roberto Salvatori; M Dodig; M S Kronenberg; B Kapural; Z Bogdanovic; Barbara E Kream; C O Woody; S H Clark; K Mack
Regulation of COL1A1 expression in type I collagen producing tissues: identification of a 49 base pair region which is required for transgene expression in bone of transgenic mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1995;10(10):1443-51.
1995: Barbara E Kream; John R Harrison; Paul H Krebsbach; Z Bogdanovic; A Bedalov; D Pavlin; C O Woody; S H Clark; D Rowe; Alexander C Lichtler
Regulation of type I collagen gene expression in bone.
Connective tissue research 1995;31(4):261-4.
1994: Alexander C Lichtler; M L Stover; J Angilly; Barbara E Kream; David W Rowe
Isolation and characterization of the rat alpha 1(I) collagen promoter. Regulation by vitamin D.
The Journal of biological chemistry 1994;269(23):16518.
1994: A Bedalov; D T Breault; B P Sokolov; Alexander C Lichtler; I Bedalov; S H Clark; K Mack; Jaspal Singh Khillan; C O Woody; Barbara E Kream
Regulation of the alpha 1(I) collagen promoter in vascular smooth muscle cells. Comparison with other alpha 1(I) collagen-producing cells in transgenic animals and cultured cells.
The Journal of biological chemistry 1994;269(7):4903-9.
1994: Z Bogdanovic; A Bedalov; Paul H Krebsbach; D Pavlin; C O Woody; S H Clark; H F Thomas; David W Rowe; Barbara E Kream; Alexander C Lichtler
Upstream regulatory elements necessary for expression of the rat COL1A1 promoter in transgenic mice.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1994;9(2):285-92.
1993: Lawrence G Raisz; P M Fall; B Y Gabbitas; T L McCarthy; Barbara E Kream; E Canalis
Effects of prostaglandin E2 on bone formation in cultured fetal rat calvariae: role of insulin-like growth factor-I.
Endocrinology 1993;133(4):1504-10.
1993: Paul H Krebsbach; John R Harrison; Alexander C Lichtler; C O Woody; David W Rowe; Barbara E Kream
Transgenic expression of COL1A1-chloramphenicol acetyltransferase fusion genes in bone: differential utilization of promoter elements in vivo and in cultured cells.
Molecular and cellular biology 1993;13(9):5168-74.
1993: Marja M Hurley; C Abreu; John R Harrison; Alexander C Lichtler; Lawrence G Raisz; Barbara E Kream
Basic fibroblast growth factor inhibits type I collagen gene expression in osteoblastic MC3T3-E1 cells.
The Journal of biological chemistry 1993;268(8):5588-93.
1993: Barbara E Kream; D LaFrancis; D N Petersen; C Woody; S Clark; David W Rowe; Alexander C Lichtler
Parathyroid hormone represses alpha 1(I) collagen promoter activity in cultured calvariae from neonatal transgenic mice.
Molecular endocrinology (Baltimore, Md.) 1993;7(3):399-408.
1993: Lawrence G Raisz; P M Fall; D N Petersen; Alexander C Lichtler; Barbara E Kream
Prostaglandin E2 inhibits alpha 1(I)procollagen gene transcription and promoter activity in the immortalized rat osteoblastic clonal cell line Py1a.
Molecular endocrinology (Baltimore, Md.) 1993;7(1):17-22.
1992: D Pavlin; Alexander C Lichtler; A Bedalov; Barbara E Kream; John R Harrison; H F Thomas; G A Gronowicz; S H Clark; C O Woody; David W Rowe
Differential utilization of regulatory domains within the alpha 1(I) collagen promoter in osseous and fibroblastic cells.
The Journal of cell biology 1992;116(1):227-36.
1990: Marja M Hurley; Barbara E Kream; Lawrence G Raisz
Structural determinants of the capacity of heparin to inhibit collagen synthesis in 21-day fetal rat calvariae.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1990;5(11):1127-33.
1990: Barbara E Kream; D N Petersen; Lawrence G Raisz
Cortisol enhances the anabolic effects of insulin-like growth factor I on collagen synthesis and procollagen messenger ribonucleic acid levels in cultured 21-day fetal rat calvariae.
Endocrinology 1990;126(3):1576-83.
1990: Marja M Hurley; G Gronowicz; Barbara E Kream; Lawrence G Raisz
Effect of heparin on bone formation in cultured fetal rat calvaria.
Calcified tissue international 1990;46(3):183-8.
1990: John R Harrison; S J Vargas; D N Petersen; J A Lorenzo; Barbara E Kream
Interleukin-1 alpha and phorbol ester inhibit collagen synthesis in osteoblastic MC3T3-E1 cells by a transcriptional mechanism.
Molecular endocrinology (Baltimore, Md.) 1990;4(2):184-90.
1990: Marja M Hurley; D L Martin; Barbara E Kream; Lawrence G Raisz
Effects of ethanol and acetaldehyde on collagen synthesis, prostaglandin release and resorption of fetal rat bone in organ culture.
Bone 1990;11(1):47-51.
1990: Barbara E Kream; D N Petersen; Lawrence G Raisz
Parathyroid hormone blocks the stimulatory effect of insulin-like growth factor-I on collagen synthesis in cultured 21-day fetal rat calvariae.
Bone 1990;11(6):411-5.
1989: Marja M Hurley; P Fall; John R Harrison; D N Petersen; Barbara E Kream; Lawrence G Raisz
Effects of transforming growth factor alpha and interleukin-1 on DNA synthesis, collagen synthesis, procollagen mRNA levels, and prostaglandin E2 production in cultured fetal rat calvaria.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1989;4(5):731-6.
1989: R G Craig; David W Rowe; D N Petersen; Barbara E Kream
Insulin increases the steady state level of alpha-1(I) procollagen mRNA in the osteoblast-rich segment of fetal rat calvaria.
Endocrinology 1989;125(3):1430-7.
1989: John R Harrison; D N Petersen; Alexander C Lichtler; A T Mador; David W Rowe; Barbara E Kream
1,25-Dihydroxyvitamin D3 inhibits transcription of type I collagen genes in the rat osteosarcoma cell line ROS 17/2.8.
Endocrinology 1989;125(1):327-33.
1989: Alexander C Lichtler; M L Stover; J Angilly; Barbara E Kream; David W Rowe
Isolation and characterization of the rat alpha 1(I) collagen promoter. Regulation by 1,25-dihydroxyvitamin D.
The Journal of biological chemistry 1989;264(6):3072-7.
1989: Barbara E Kream; J Harrison; R Bailey; D Petersen; D Rowe; Alexander C Lichtler
Hormonal regulation of collagen gene expression in osteoblastic cell-overview and new findings.
Connective tissue research 1989;20(1-4):187-92.
1988: Hyun-Duck Nah; B J Rodgers; W M Kulyk; Barbara E Kream; Robert A Kosher; William B Upholt
In situ hybridization analysis of the expression of the type II collagen gene in the developing chicken limb bud.
Collagen and related research 1988;8(4):277-94.
1988: B O Hodge; Barbara E Kream
Variable effects of dexamethasone on protein synthesis in clonal rat osteosarcoma cells.
Endocrinology 1988;122(5):2127-33.
1988: J H Feyen; D N Petersen; Barbara E Kream
Inhibition of bone collagen synthesis by the tumor promoter phorbol 12-myristate 13-acetate.
Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research 1988;3(2):173-9.
1982: David W Rowe; Barbara E Kream
Regulation of collagen synthesis in fetal rat calvaria by 1,25-dihydroxyvitamin D3.
The Journal of biological chemistry 1982;257(14):8009-15.
1980: Barbara E Kream; David W Rowe; S C Gworek; L G Raisz
Parathyroid hormone alters collagen synthesis and procollagen mRNA levels in fetal rat calvaria.
Proceedings of the National Academy of Sciences of the United States of America 1980;77(10):5654-8.