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Marcus Kremer

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Kathrin Endt; Manja Barthel; Rina Käppeli; Marcus Kremer; Lisa Maier; Benjamin Misselwitz; Wolf-Dietrich Hardt
Peroral ciprofloxacin therapy impairs the generation of a protective immune response in a mouse model for Salmonella enterica serovar Typhimurium diarrhea, while parenteral ceftriaxone therapy does not.
Andreas J Müller; Pascal Songhet; Thomas C Weber; Christa Zellweger; Kurt E J Dittmar; Kathrin Endt; Hans-Jörg Fehling; Sabine Haueter; Patrick Kaiser; Marcus Kremer; Wolf-Dietrich Hardt
Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes.
Balamurugan Periaswamy; Emma Slack; Mrutyunjay Suar; Vikalp Vishwakarma; Helene L Andrews-Polymenis; Andrew J Grant; Marcus Kremer; Lisa Maier; Michael McClelland; Wolf-Dietrich Hardt
Live attenuated S. Typhimurium vaccine with improved safety in immuno-compromised mice.

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2012: Kathrin Endt; Manja Barthel; Rina Käppeli; Marcus Kremer; Lisa Maier; Benjamin Misselwitz; Wolf-Dietrich Hardt
Peroral ciprofloxacin therapy impairs the generation of a protective immune response in a mouse model for Salmonella enterica serovar Typhimurium diarrhea, while parenteral ceftriaxone therapy does not.
Antimicrobial agents and chemotherapy 2012;56(5):2295-304.
2012: Andreas J Müller; Pascal Songhet; Thomas C Weber; Christa Zellweger; Kurt E J Dittmar; Kathrin Endt; Hans-Jörg Fehling; Sabine Haueter; Patrick Kaiser; Marcus Kremer; Wolf-Dietrich Hardt
Salmonella gut invasion involves TTSS-2-dependent epithelial traversal, basolateral exit, and uptake by epithelium-sampling lamina propria phagocytes.
Cell host & microbe 2012;11(1):19-32.
2012: Balamurugan Periaswamy; Emma Slack; Mrutyunjay Suar; Vikalp Vishwakarma; Helene L Andrews-Polymenis; Andrew J Grant; Marcus Kremer; Lisa Maier; Michael McClelland; Wolf-Dietrich Hardt
Live attenuated S. Typhimurium vaccine with improved safety in immuno-compromised mice.
PloS one 2012;7(9):e45433.
2011: Pascal Songhet; Bärbel Stecher; Manja Barthel; Gunnar C Hansson; Marcus Kremer; Andreas J Müller; Wolf-Dietrich Hardt
Stromal IFN-γR-signaling modulates goblet cell function during Salmonella Typhimurium infection.
PloS one 2011;6(7):e22459.
2010: Jürgen den Hollander; Sara Rimpi; Joanne R Doherty; Martina Rudelius; Andreas Buck; Alexander Hoellein; Marcus Kremer; Nikolas Graf; Markus Scheerer; Mark A Hall; Andrei Goga; Nikolas von Bubnoff; Justus Duyster; Christian Peschel; John L Cleveland; Jonas A Nilsson; Ulrich Keller
Aurora kinases A and B are up-regulated by Myc and are essential for maintenance of the malignant state.
Blood 2010;116(9):1498-505.
2010: Volker R Jacobs; Iris Zemzoum; Marcus Kremer; Nina Gottschalk; Anne K Baumgärtner; Janna Krol; Marion Kiechle
Primary metastatic leiomyosarcoma of the fallopian tube: a rare case report.
Onkologie 2010;33(1-2):49-52.
2009: Andreas Schweikert; Marcus Kremer; Florian Ringel; Thomas Liebig; Justus Duyster; Olaf Stüve; Bernhard Hemmer; Achim Berthele
Primary central nervous system lymphoma in a patient treated with natalizumab.
Annals of neurology 2009;66(3):403-6.
2009: Mrutyunjay Suar; Balamurugan Periaswamy; Pascal Songhet; Benjamin Misselwitz; Andreas Müller; Rina Käppeli; Marcus Kremer; Mathias Heikenwalder; Wolf-Dietrich Hardt
Accelerated type III secretion system 2-dependent enteropathogenesis by a Salmonella enterica serovar enteritidis PT4/6 strain.
Infection and immunity 2009;77(9):3569-77.
2009: Andreas J Müller; Claudia Hoffmann; Marlies Galle; Aeke Van Den Broeke; Mathias Heikenwalder; Laura Falter; Benjamin Misselwitz; Marcus Kremer; Rudi Beyaert; Wolf-Dietrich Hardt
The S. Typhimurium effector SopE induces caspase-1 activation in stromal cells to initiate gut inflammation.
Cell host & microbe 2009;6(2):125-36.
2009: Rupert Langer; Aurel Perren; Karen Becker; Robert B Brauer; Julia Dinges; Martin Dobritz; Marcus Kremer
Sclerosing angiomatoid nodular transformation of the spleen presenting as a rapidly growing tumour in a patient with rectal cancer.
BMJ case reports 2009;2009():.
2008: Marcus Kremer; Thomas Horn; Ina Koch; Tobias Dechow; Stefan Gattenloehner; Walter Pfeiffer; Leticia Quintanilla-Martínez; Falko Fend
Quantitation of the JAK2V617F mutation in microdissected bone marrow trephines: equal mutational load in myeloid lineages and rare involvement of lymphoid cells.
The American journal of surgical pathology 2008;32(6):928-35.
2008: Bärbel Stecher; Manja Barthel; Markus C Schlumberger; Lea Haberli; Wolfgang Rabsch; Marcus Kremer; Wolf-Dietrich Hardt
Motility allows S. Typhimurium to benefit from the mucosal defence.
Cellular microbiology 2008;10(5):1166-80.
2008: Siegfried Hapfelmeier; Andreas J Müller; Bärbel Stecher; Patrick Kaiser; Manja Barthel; Kathrin Endt; Matthias Eberhard; Riccardo Robbiani; Christoph A Jacobi; Mathias Heikenwalder; Carsten Kirschning; Steffen Jung; Thomas Stallmach; Marcus Kremer; Wolf-Dietrich Hardt
Microbe sampling by mucosal dendritic cells is a discrete, MyD88-independent step in DeltainvG S. Typhimurium colitis.
The Journal of experimental medicine 2008;205(2):437-50.
2008: Falko Fend; Alexandar Tzankov; Karin Bink; Stefan Seidl; Leticia Quintanilla-Martinez; Marcus Kremer; Stephan Dirnhofer
Modern techniques for the diagnostic evaluation of the trephine bone marrow biopsy: methodological aspects and applications.
Progress in histochemistry and cytochemistry 2008;42(4):203-52.
2008: Julia Slotta-Huspenina; Ina Koch; Manfred Richter; Karin Bink; Marcus Kremer; Katja Specht; Jens Krugmann; Leticia Quintanilla-Martinez; Falko Fend
Cyclin D1 positive multiple myeloma: predominance of the short, 3'UTR-deficient transcript is associated with high cyclin D1 mRNA levels in cases with t(11;14) translocation, but does not correlate with proliferation rate or genomic deletions.
Leukemia research 2008;32(1):79-88.
2007: Kareen Blechschmidt; Elisabeth Kremmer; Regina Hollweck; Ioannis Mylonas; Heinz Höfler; Marcus Kremer; Karl-Friedrich Becker
The E-cadherin repressor snail plays a role in tumor progression of endometrioid adenocarcinomas.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2007;16(4):222-8.
2007: Bärbel Stecher; Riccardo Robbiani; Alan W Walker; Astrid M Westendorf; Manja Barthel; Marcus Kremer; Samuel Chaffron; Andrew J Macpherson; Jan Buer; Julian Parkhill; Gordon Dougan; Christian von Mering; Wolf-Dietrich Hardt
Salmonella enterica serovar typhimurium exploits inflammation to compete with the intestinal microbiota.
PLoS biology 2007;5(10):2177-89.
2007: Markus C Schlumberger; Rina Käppeli; Michael Wetter; Andreas J Müller; Benjamin Misselwitz; Sabrina Dilling; Marcus Kremer; Wolf-Dietrich Hardt
Two newly identified SipA domains (F1, F2) steer effector protein localization and contribute to Salmonella host cell manipulation.
Molecular microbiology 2007;65(3):741-60.
2007: Falko Fend; Marcus Kremer
Diagnosis and classification of malignant lymphoma and related entities in the bone marrow trephine biopsy.
Pathobiology : journal of immunopathology, molecular and cellular biology 2007;74(2):133-43.
2006: Bärbel Stecher; Guenther Paesold; Manja Barthel; Marcus Kremer; Jonathan Jantsch; Thomas Stallmach; Mathias Heikenwalder; Wolf-Dietrich Hardt
Chronic Salmonella enterica serovar Typhimurium-induced colitis and cholangitis in streptomycin-pretreated Nramp1+/+ mice.
Infection and immunity 2006;74(9):5047-57.
2006: Thomas Horn; Marcus Kremer; Tobias Dechow; Walther M Pfeifer; Birgit Geist; Michael Perker; Justus Duyster; Leticia Quintanilla-Martinez; Falko Fend
Detection of the activating JAK2 V617F mutation in paraffin-embedded trephine bone marrow biopsies of patients with chronic myeloproliferative diseases.
The Journal of molecular diagnostics : JMD 2006;8(3):299-304.
2006: Marcus Kremer; T Horn; Tobias Dechow; A Tzankov; Leticia Quintanilla-Martínez; Falko Fend
The JAK2 V617F mutation occurs frequently in myelodysplastic/myeloproliferative diseases, but is absent in true myelodysplastic syndromes with fibrosis.
Leukemia 2006;20(7):1315-6.
2006: Michael Rosemann; Virginija Kuosaite; Marcus Kremer; Jack Favor; Leticia Quintanilla-Martinez; Michael J Atkinson
Multilocus inheritance determines predisposition to alpha-radiation induced bone tumourigenesis in mice.
International journal of cancer. Journal international du cancer 2006;118(9):2132-8.
2006: Mrutyunjay Suar; Jonathan Jantsch; Siegfried Hapfelmeier; Marcus Kremer; Thomas Stallmach; Paul A Barrow; Wolf-Dietrich Hardt
Virulence of broad- and narrow-host-range Salmonella enterica serovars in the streptomycin-pretreated mouse model.
Infection and immunity 2006;74(1):632-44.
2005: Falko Fend; Oliver Bock; Marcus Kremer; Katja Specht; Leticia Quintanilla-Martinez
Ancillary techniques in bone marrow pathology: molecular diagnostics on bone marrow trephine biopsies.
Virchows Archiv : an international journal of pathology 2005;447(6):909-19.
2005: Marcus Kremer; Leticia Quintanilla-Martínez; Jörg Nährig; Christoph von Schilling; Falko Fend
Immunohistochemistry in bone marrow pathology: a useful adjunct for morphologic diagnosis.
Virchows Archiv : an international journal of pathology 2005;447(6):920-37.
2005: Bärbel Stecher; Andrew J Macpherson; Siegfried Hapfelmeier; Marcus Kremer; Thomas Stallmach; Wolf-Dietrich Hardt
Comparison of Salmonella enterica serovar Typhimurium colitis in germfree mice and mice pretreated with streptomycin.
Infection and immunity 2005;73(6):3228-41.
2005: Siegfried Hapfelmeier; Bärbel Stecher; Manja Barthel; Marcus Kremer; Andreas J Müller; Mathias Heikenwalder; Thomas Stallmach; Michael Hensel; Klaus Pfeffer; Shizuo Akira; Wolf-Dietrich Hardt
The Salmonella pathogenicity island (SPI)-2 and SPI-1 type III secretion systems allow Salmonella serovar typhimurium to trigger colitis via MyD88-dependent and MyD88-independent mechanisms.
Journal of immunology (Baltimore, Md. : 1950) 2005;174(3):1675-85.
2005: Stephan Schulz; Antonello Domenico Cabras; Marcus Kremer; Gregor Weirich; Thomas Miethke; Hans-Christian Bösmüller; Heinz Höfler; Martin Werner; Falko Fend
Species identification of mycobacteria in paraffin-embedded tissues: frequent detection of nontuberculous mycobacteria.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2005;18(2):274-82.
2005: Marcus Kremer; German Ott; Michaela Nathrath; Katja Specht; Katrin Stecker; Christoph Alexiou; Leticia Quintanilla-Martinez; Falko Fend
Primary extramedullary plasmacytoma and multiple myeloma: phenotypic differences revealed by immunohistochemical analysis.
The Journal of pathology 2005;205(1):92-101.
2004: Katja Specht; Eugenia Haralambieva; Karin Bink; Marcus Kremer; Sonja Mandl-Weber; Ina Koch; Raju Tomer; Heinz Hofler; Ed Schuuring; Philip M Kluin; Falko Fend; Leticia Quintanilla-Martinez
Different mechanisms of cyclin D1 overexpression in multiple myeloma revealed by fluorescence in situ hybridization and quantitative analysis of mRNA levels.
Blood 2004;104(4):1120-6.
2004: Bärbel Stecher; Siegfried Hapfelmeier; Catherine Müller; Marcus Kremer; Thomas Stallmach; Wolf-Dietrich Hardt
Flagella and chemotaxis are required for efficient induction of Salmonella enterica serovar Typhimurium colitis in streptomycin-pretreated mice.
Infection and immunity 2004;72(7):4138-50.
2004: Siegfried Hapfelmeier; Kristin Ehrbar; Bärbel Stecher; Manja Barthel; Marcus Kremer; Wolf-Dietrich Hardt
Role of the Salmonella pathogenicity island 1 effector proteins SipA, SopB, SopE, and SopE2 in Salmonella enterica subspecies 1 serovar Typhimurium colitis in streptomycin-pretreated mice.
Infection and immunity 2004;72(2):795-809.
2003: Marcus Kremer; Leticia Quintanilla-Martinez; Margit Fuchs; Armando Gamboa-Dominguez; Sieglinde Haye; Holger Kalthoff; Erika Rosivatz; Christine Hermannstädter; Raymonde Busch; Heinz Höfler; Birgit Luber
Influence of tumor-associated E-cadherin mutations on tumorigenicity and metastasis.
Carcinogenesis 2003;24(12):1879-86.
2003: Leticia Quintanilla-Martinez; Marcus Kremer; Katja Specht; Julia Calzada-Wack; Michaela Nathrath; Robert Schaich; Heinz Höfler; Falko Fend
Analysis of signal transducer and activator of transcription 3 (Stat 3) pathway in multiple myeloma: Stat 3 activation and cyclin D1 dysregulation are mutually exclusive events.
The American journal of pathology 2003;162(5):1449-61.
2003: Manja Barthel; Siegfried Hapfelmeier; Leticia Quintanilla-Martínez; Marcus Kremer; Manfred Rohde; Michael Hogardt; Klaus Pfeffer; Holger Rüssmann; Wolf-Dietrich Hardt
Pretreatment of mice with streptomycin provides a Salmonella enterica serovar Typhimurium colitis model that allows analysis of both pathogen and host.
Infection and immunity 2003;71(5):2839-58.
2003: Falko Fend; Marcus Kremer; Katja Specht; Leticia Quintanilla-Martinez
Laser microdissection in hematopathology.
Pathology, research and practice 2003;199(6):425-30.
2003: Marcus Kremer; Martin Spitzer; Sonja Mandl-Weber; Katrin Stecker; Burkhard Schmidt; Heinz Höfler; Leticia Quintanilla-Martínez; Falko Fend
Discordant bone marrow involvement in diffuse large B-cell lymphoma: comparative molecular analysis reveals a heterogeneous group of disorders.
Laboratory investigation; a journal of technical methods and pathology 2003;83(1):107-14.
2002: Katja Specht; Marcus Kremer; Ulrike Müller; Stephan Dirnhofer; Michael Rosemann; Heinz Höfler; Leticia Quintanilla-Martinez; Falko Fend
Identification of cyclin D1 mRNA overexpression in B-cell neoplasias by real-time reverse transcription-PCR of microdissected paraffin sections.
Clinical cancer research : an official journal of the American Association for Cancer Research 2002;8(9):2902-11.
2002: Michaela Nathrath; Virginija Kuosaite; Michael Rosemann; Marcus Kremer; Christopher Poremba; Shigeharu Wakana; Masayuki Yanagi; Walter B J Nathrath; Heinz Höfler; Kenji Imai; Michael J Atkinson
Two novel tumor suppressor gene loci on chromosome 6q and 15q in human osteosarcoma identified through comparative study of allelic imbalances in mouse and man.
Oncogene 2002;21(38):5975-80.
2002: Michaela Nathrath; Marcus Kremer; H Letzel; K Remberger; Heinz Höfler; T Ulle
[Expression of genes of potential importance in the response to chemotherapy in osteosarcoma patients].
Klinische Pädiatrie 2002;214(4):230-5.
2002: Falko Fend; Katja Specht; Marcus Kremer; Leticia Quintanilla-Martínez
Laser capture microdissection in pathology.
Methods in enzymology 2002;356():196-206.
2001: Leticia Quintanilla-Martinez; Marcus Kremer; G Keller; Michaela Nathrath; Armando Gamboa-Dominguez; A Meneses; L Luna-Contreras; Antonello Domenico Cabras; Heinz Hoefler; Alejandro Mohar; Falko Fend
p53 Mutations in nasal natural killer/T-cell lymphoma from Mexico: association with large cell morphology and advanced disease.
The American journal of pathology 2001;159(6):2095-105.
2001: Marcus Kremer; S Dirnhofer; A Nickl; Heinz Hoefler; Leticia Quintanilla-Martínez; Falko Fend
p27(Kip1) immunostaining for the differential diagnosis of small b-cell neoplasms in trephine bone marrow biopsies.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(10):1022-9.
2001: Antonello Domenico Cabras; S Candidus; Falko Fend; Marcus Kremer; S Schulz; Cesare Bordi; Gregor Weirich; Heinz Höfler; Martin Werner
Biclonality of gastric lymphomas.
Laboratory investigation; a journal of technical methods and pathology 2001;81(7):961-7.
2001: Marcus Kremer; M Sandherr; B Geist; Antonello Domenico Cabras; Heinz Höfler; Falko Fend
Epstein-Barr virus-negative Hodgkin's lymphoma after mycosis fungoides: molecular evidence for distinct clonal origin.
Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc 2001;14(2):91-7.
2000: Marcus Kremer; Antonello Domenico Cabras; Falko Fend; S Schulz; K Schwarz; Heinz Hoefler; Martin Werner
PCR analysis of IgH-gene rearrangements in small lymphoid infiltrates microdissected from sections of paraffin-embedded bone marrow biopsy specimens.
Human pathology 2000;31(7):847-53.
2000: Michaela Aubele; M C Cummings; AE Mattis; Horst Zitzelsberger; Axel Walch; Marcus Kremer; Heinz Höfler; Martin Werner
Accumulation of chromosomal imbalances from intraductal proliferative lesions to adjacent in situ and invasive ductal breast cancer.
Diagnostic molecular pathology : the American journal of surgical pathology, part B 2000;9(1):14-9.
2000: Falko Fend; Marcus Kremer; Leticia Quintanilla-Martinez
Laser capture microdissection: methodical aspects and applications with emphasis on immuno-laser capture microdissection.
Pathobiology : journal of immunopathology, molecular and cellular biology 2000;68(4-5):209-14.
2000: Michaela Aubele; AE Mattis; Horst Zitzelsberger; Axel Walch; Marcus Kremer; Gerhard Welzl; Heinz Höfler; Martin Werner
Extensive ductal carcinoma In situ with small foci of invasive ductal carcinoma: evidence of genetic resemblance by CGH.
International journal of cancer. Journal international du cancer 2000;85(1):82-6.
1999: Michaela Aubele; AE Mattis; Horst Zitzelsberger; Axel Walch; Marcus Kremer; Peter Hutzler; Heinz Höfler; Martin Werner
Intratumoral heterogeneity in breast carcinoma revealed by laser-microdissection and comparative genomic hybridization.
Cancer genetics and cytogenetics 1999;110(2):94-102.