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Vladimír Kren

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Pavla Bojarová; Vladimír Kren
Glycosidases in carbohydrate synthesis: when organic chemistry falls short.
Natallia Kulik; Lenka Weignerová; Tomás Filipi; Petr Pompach; Petr Novák; Hynek Mrázek; Kristyna Slámová; Karel Bezouska; Vladimír Kren; Rüdiger Ettrich
The α-galactosidase type A gene aglA from Aspergillus niger encodes a fully functional α-N-acetylgalactosaminidase.
Kristýna Slámová; Pavla Bojarová; Lucie Petrásková; Vladimír Kren
β-N-acetylhexosaminidase: what's in a name…?

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All Publications

2011: Pavla Bojarová; Vladimír Kren
Glycosidases in carbohydrate synthesis: when organic chemistry falls short.
Chimia 2011;65(1-2):65-70.
2010: Natallia Kulik; Lenka Weignerová; Tomás Filipi; Petr Pompach; Petr Novák; Hynek Mrázek; Kristyna Slámová; Karel Bezouska; Vladimír Kren; Rüdiger Ettrich
The α-galactosidase type A gene aglA from Aspergillus niger encodes a fully functional α-N-acetylgalactosaminidase.
Glycobiology 2010;20(11):1410-9.
2010: Kristýna Slámová; Pavla Bojarová; Lucie Petrásková; Vladimír Kren
β-N-acetylhexosaminidase: what's in a name…?
Biotechnology advances 2010;28(6):682-93.
2010: Kristyna Slámová; Radek Gazák; Pavla Bojarová; Natallia Kulik; Rüdiger Ettrich; Helena Pelantová; Petr Sedmera; Vladimír Kren
4-Deoxy-substrates for beta-N-acetylhexosaminidases: how to make use of their loose specificity.
Glycobiology 2010;20(8):1002-9.
2010: Kristýna Slámová; P Marhol; Karel Bezouska; Lise Lindkvist; Signe G Hansen; Vladimír Kren; Henrik H Jensen
Synthesis and biological activity of glycosyl-1H-1,2,3-triazoles.
Bioorganic & medicinal chemistry letters 2010;20(14):4263-5.
2010: Anna Kovalová; Miroslav Ledvina; David Saman; Daniel Zyka; Monika Kubícková; Lukás Zídek; Vladimír Sklenár; Petr Pompach; Daniel Kavan; Jan Bílý; Ondrej Vanek; Zuzana Kubínková; Martina Libigerová; Ljubina Ivanová; Mária Antolíková; Hynek Mrázek; Daniel Rozbeský; Katerina Hofbauerová; Vladimír Kren; Karel Bezouska
Synthetic N-acetyl-D-glucosamine based fully branched tetrasaccharide, a mimetic of the endogenous ligand for CD69, activates CD69+ killer lymphocytes upon dimerization via a hydrophilic flexible linker.
Journal of medicinal chemistry 2010;53(10):4050-65.
2010: Olivier Renaudet; Karel Krenek; Isabelle Bossu; Pascal DUMY; Alan Kádek; David Adámek; Ondrej Vanek; Daniel Kavan; Radek Gazák; Miroslav Sulc; Karel Bezouska; Vladimír Kren
Synthesis of multivalent glycoconjugates containing the immunoactive LELTE peptide: effect of glycosylation on cellular activation and natural killing by human peripheral blood mononuclear cells.
Journal of the American Chemical Society 2010;132(19):6800-8.
2010: Daniel Kavan; Monika Kubícková; Jan Bílý; Ondrej Vanek; Katerina Hofbauerová; Hynek Mrázek; Daniel Rozbeský; Pavla Bojarová; Vladimír Kren; Lukás Zídek; Vladimír Sklenár; Karel Bezouska
Cooperation between subunits is essential for high-affinity binding of N-acetyl-D-hexosamines to dimeric soluble and dimeric cellular forms of human CD69.
Biochemistry 2010;49(19):4060-7.
2010: Ludmila Martínková; Vladimír Kren
Biotransformations with nitrilases.
Current opinion in chemical biology 2010;14(2):130-7.
2010: Radek Gazák; Katerina Purchartová; P Marhol; Lucie Zivná; Petr Sedmera; Katerina Valentová; Nobuo Kato; Hiroyo Matsumura; Kunihiro Kaihatsu; Vladimír Kren
Antioxidant and antiviral activities of silybin fatty acid conjugates.
European journal of medicinal chemistry 2010;45(3):1059-67.
2010: Karel Bezouska; Renata Snajdrová; Karel Krenek; Markéta Vancurová; Alan Kádek; David Adámek; Pavel Lhoták; Daniel Kavan; Katerina Hofbauerová; Petr Man; Pavla Bojarová; Vladimír Kren
Carboxylated calixarenes bind strongly to CD69 and protect CD69(+) killer cells from suicidal cell death induced by tumor cell surface ligands.
Bioorganic & medicinal chemistry 2010;18(4):1434-40.
2010: Lenka Weignerová; Vladimír Kren
Enzymatic processing of bioactive glycosides from natural sources.
Topics in current chemistry 2010;295():121-46.
2010: Michaela Krupková; Lucie Sedová; Frantisek Liska; Drahomíra Krenová; Vladimír Kren; Ondrej Seda
Pharmacogenetic interaction between dexamethasone and Cd36-deficient segment of spontaneously hypertensive rat chromosome 4 affects triacylglycerol and cholesterol distribution into lipoprotein fractions.
Lipids in health and disease 2010;9():38.
2010: Yongming Wang; Frantisek Liska; Claudia Gosele; Lucie Sedová; Vladimír Kren; Drahomíra Krenová; Zoltán Ivics; Norbert Hubner; Zsuzsanna Izsvák
A novel active endogenous retrovirus family contributes to genome variability in rat inbred strains.
Genome research 2010;20(1):19-27.
2009: Michaela Krupková; Michaela Janků; Frantisek Liska; Lucie Sedová; Ludmila Kazdová; Drahomíra Krenová; Vladimír Kren; Ondrej Seda
Pharmacogenetic model of retinoic acid-induced dyslipidemia and insulin resistance.
Pharmacogenomics 2009;10(12):1915-27.
2009: Frantisek Liska; Claudia Gosele; Eugene Rivkin; Laura Tres; M Cristina Cardoso; Petra Domaing; Eliska Krejcí; Pavel Snajdr; Min Ae Lee-Kirsch; Dirk G de Rooij; Dirk G de Rooij; Vladimír Kren; Drahomíra Krenová; Abraham L Kierszenbaum; Norbert Hubner
Rat hd mutation reveals an essential role of centrobin in spermatid head shaping and assembly of the head-tail coupling apparatus.
Biology of reproduction 2009;81(6):1196-205.
2009: Ludmila Martínková; Vojtech Vejvoda; Ondrej Kaplan; David Kubác; Anna Malandra; Maria Cantarella; Karel Bezouska; Vladimír Kren
Fungal nitrilases as biocatalysts: Recent developments.
Biotechnology advances 2009;27(6):661-70.
2009: Céline Bourdon; Silvie Hojna; Melissa Jordan; Julie Bérubé; Vladimír Kren; Michal Pravenec; Peter Liu; Sara Arab; Zdenka Pausová
Genetic locus on rat chromosome 20 regulates diet-induced adipocyte hypertrophy: a microarray gene expression study.
Physiological genomics 2009;38(1):63-72.
2009: Pavla Bojarová; Karel Krenek; Katharina Wetjen; Kathrin Adamiak; Helena Pelantová; Karel Bezouska; Lothar Elling; Vladimír Kren
Synthesis of LacdiNAc-terminated glycoconjugates by mutant galactosyltransferase--a way to new glycodrugs and materials.
Glycobiology 2009;19(5):509-17.
2009: Pavla Bojarová; Vladimír Kren
Glycosidases: a key to tailored carbohydrates.
Trends in biotechnology 2009;27(4):199-209.
2009: Radek Gazák; Petr Sedmera; Marek Vrbacký; Jitka Vostálová; Zdenek Drahota; P Marhol; Daniela Walterová; Vladimír Kren
Molecular mechanisms of silybin and 2,3-dehydrosilybin antiradical activity--role of individual hydroxyl groups.
Free radical biology & medicine 2009;46(6):745-58.
2009: Frantisek Liska; Pavel Snajdr; Lucie Sedová; Ondrej Seda; Blanka Chylíková; Petra Slámová; Eliska Krejcí; David Sedmera; Milos Grim; Drahomíra Krenová; Vladimír Kren
Deletion of a conserved noncoding sequence in Plzf intron leads to Plzf down-regulation in limb bud and polydactyly in the rat.
Developmental dynamics : an official publication of the American Association of Anatomists 2009;238(3):673-84.
2009: Karen J Loft; Pavla Bojarová; Kristýna Slámová; Vladimír Kren; Spencer J Williams
Synthesis of sulfated glucosaminides for profiling substrate specificities of sulfatases and fungal beta-N-acetylhexosaminidases.
Chembiochem : a European journal of chemical biology 2009;10(3):565-76.
2009: Ludmila Martínková; Bronislava Uhnáková; Miroslav Pátek; Jan Nesvera; Vladimír Kren
Biodegradation potential of the genus Rhodococcus.
Environment international 2009;35(1):162-77.
2008: Vladimír Kren; Tomás Rezanka
Sweet antibiotics - the role of glycosidic residues in antibiotic and antitumor activity and their randomization.
FEMS microbiology reviews 2008;32(5):858-89.
2008: Michal Pravenec; Paul C Churchill; Monique C Churchill; Ondrej Viklicky; Ludmila Kazdova; Timothy J Aitman; Enrico Petretto; Norbert Hubner; Caroline A Wallace; Heike Zimdahl; Vaclav Zidek; Vladimir Landa; Joseph Dunbar; Anil K Bidani; Karen Griffin; Nianning Qi; Martina Maxova; Vladimír Kren; Petr Mlejnek; Jiaming Wang; theodore kurtz
Identification of renal Cd36 as a determinant of blood pressure and risk for hypertension.
Nature genetics 2008;40(8):952-4.
2008: Lenka Weignerová; T Filipi; D Manglová; Vladimír Kren
Induction, purification and characterization of alpha-N-acetylgalactosaminidase from Aspergillus Niger.
Applied microbiology and biotechnology 2008;79(5):769-74.
2008: Ken Sugimoto; Ludmila Kazdová; Nianning Qi; Masaya Hyakukoku; Vladimír Kren; Miroslava Simáková; Václav Zídek; theodore kurtz; Michal Pravenec
Telmisartan increases fatty acid oxidation in skeletal muscle through a peroxisome proliferator-activated receptor-gamma dependent pathway.
Journal of hypertension 2008;26(6):1209-15.
2008: Enrico Petretto; Rizwan Sarwar; Ian Grieve; Han Lu; Mande K Kumaran; Phillip J Muckett; Jonathan Mangion; Blanche Schroen; Matthew Benson; Prakash P Punjabi; Sanjay K Prasad; Dudley J Pennell; Chris Kiesewetter; Elena S Tasheva; Lolita M Corpuz; Megan D Webb; Gary W Conrad; theodore kurtz; Vladimír Kren; Judith Fischer; Norbert Hubner; Yigal M Pinto; Michal Pravenec; Timothy J Aitman; Stuart A Cook
Integrated genomic approaches implicate osteoglycin (Ogn) in the regulation of left ventricular mass.
Nature genetics 2008;40(5):546-52.
2008: Patrick Trouillas; Philippe Marsal; Alena Svobodová; Jitka Vostálová; Radek Gazák; Jan Hrbác; Petr Sedmera; Vladimír Kren; Roberto Lazzaroni; Jean-Luc Duroux; Daniela Walterová
Mechanism of the antioxidant action of silybin and 2,3-dehydrosilybin flavonolignans: a joint experimental and theoretical study.
The journal of physical chemistry. A 2008;112(5):1054-63.
2008: Ondrej Seda; Lucie Sedová; Olena Oliyarnyk; Ludmila Kazdová; Drahomíra Krenová; Gilles Corbeil; Pavel Hamet; Johanne Tremblay; Vladimír Kren
Pharmacogenomics of metabolic effects of rosiglitazone.
Pharmacogenomics 2008;9(2):141-55.
2008: Ludmila Martínková; Vojtech Vejvoda; Vladimír Kren
Selection and screening for enzymes of nitrile metabolism.
Journal of biotechnology 2008;133(3):318-26.
2008: Frantisek Liska; Blanka Chylíková; Jindrich Martínek; Vladimír Kren
Microphthalmia and cataract in rats with a novel point mutation in connexin 50 - L7Q.
Molecular vision 2008;14():823-8.
2008: Michal Pravenec; Ludmila Kazdova; Vladimir Landa; Vaclav Zidek; Petr Mlejnek; Miroslava Simakova; Petr Jansa; Jiri Forejt; Vladimír Kren; Drahomira Krenova; Nianning Qi; Jia-Ming Wang; Derrick Chan; Timothy J Aitman; theodore kurtz
Identification of mutated Srebf1 as a QTL influencing risk for hepatic steatosis in the spontaneously hypertensive rat.
Hypertension 2008;51(1):148-53.
2007: Karel Krenek; Markéta Kuldová; Katarína Hulíková; Ivan Stibor; Pavel Lhoták; Miroslav Dudic; Jan Budka; Helena Pelantová; Karel Bezouska; Anna Fiserová; Vladimír Kren
N-acetyl-D-glucosamine substituted calix[4]arenes as stimulators of NK cell-mediated antitumor immune response.
Carbohydrate research 2007;342(12-13):1781-92.
2007: Vojtech Vejvoda; Ondrej Sveda; Ondrej Kaplan; Vera Prikrylová; Veronika Elisáková; Michal Himl; David Kubác; Helena Pelantová; Marek Kuzma; Vladimír Kren; Ludmila Martínková
Biotransformation of heterocyclic dinitriles by Rhodococcus erythropolis and fungal nitrilases.
Biotechnology letters 2007;29(7):1119-24.
2007: Lucie Sedová; Ondrej Seda; Ludmila Kazdová; Blanka Chylíková; Pavel Hamet; Johanne Tremblay; Vladimír Kren; Drahomíra Krenová
Sucrose feeding during pregnancy and lactation elicits distinct metabolic response in offspring of an inbred genetic model of metabolic syndrome.
American journal of physiology. Endocrinology and metabolism 2007;292(5):E1318-24.
2007: Ondrej Plíhal; Jan Sklenár; Katerina Hofbauerová; Petr Novák; Petr Man; Petr Pompach; Daniel Kavan; Helena Ryslavá; Lenka Weignerová; Andrea Charvátová-Pisvejcová; Vladimír Kren; Karel Bezouska
Large propeptides of fungal beta-N-acetylhexosaminidases are novel enzyme regulators that must be intracellularly processed to control activity, dimerization, and secretion into the extracellular environment.
Biochemistry 2007;46(10):2719-34.
2007: Pavla Simerská; Daniela Monti; Ivana Cechová; Helena Pelantová; Martina Macková; Karel Bezouska; Sergio Riva; Vladimír Kren
Induction and characterization of an unusual alpha-D-galactosidase from Talaromyces flavus.
Journal of biotechnology 2007;128(1):61-71.
2007: Rüdiger Ettrich; Vladimír Kopecký; Katerina Hofbauerová; Vladimír Baumruk; Petr Novák; Petr Pompach; Petr Man; Ondrej Plíhal; Michal Kutý; Natallia Kulik; Jan Sklenár; Helena Ryslavá; Vladimír Kren; Karel Bezouska
Structure of the dimeric N-glycosylated form of fungal beta-N-acetylhexosaminidase revealed by computer modeling, vibrational spectroscopy, and biochemical studies.
BMC structural biology 2007;7():32.
2007: Radek Gazák; Daniela Walterová; Vladimír Kren
Silybin and silymarin--new and emerging applications in medicine.
Current medicinal chemistry 2007;14(3):315-38.
2006: Ondrej Kaplan; Vojtech Vejvoda; Ondrej Plíhal; Petr Pompach; Daniel Kavan; Pavla Bojarová; Karel Bezouska; Martina Macková; Maria Cantarella; Vladimír Jirků; Vladimír Kren; Ludmila Martínková
Purification and characterization of a nitrilase from Aspergillus niger K10.
Applied microbiology and biotechnology 2006;73(3):567-75.
2006: Enrico Petretto; Jonathan Mangion; Nicholas J Dickens; Stuart A Cook; Mande K Kumaran; Han Lu; Judith Fischer; Henrike Maatz; Vladimír Kren; Michal Pravenec; Norbert Hubner; Timothy J Aitman
Heritability and tissue specificity of expression quantitative trait loci.
PLoS genetics 2006;2(10):e172.
2006: Ondrej Seda; Lucie Sedová; Frantisek Liska; Drahomíra Krenová; Vratislav Prejzek; Ludmila Kazdová; Johanne Tremblay; Pavel Hamet; Vladimír Kren
Novel double-congenic strain reveals effects of spontaneously hypertensive rat chromosome 2 on specific lipoprotein subfractions and adiposity.
Physiological genomics 2006;27(1):95-102.
2006: Lucie Petrásková; Andrea Charvátová; Vera Prikrylová; Veronika Kristová; Jana Rauvolfová; Ludmila Martínková; Jesús Jiménez-Barbero; Nuria Aboitiz; Ladislav Petrus; Vladimír Kren
Preparative production and separation of 2-acetamido-2-deoxymannopyranoside-containing saccharides using borate-saturated polyolic exclusion gels.
Journal of chromatography. A 2006;1127(1-2):126-36.
2006: Martina Buresova; Vaclav Zidek; Alena Musilova; Miroslava Simakova; Alena Fucikova; Vlasta Bila; Vladimír Kren; Ludmila Kazdova; Robert Di Nicolantonio; Michal Pravenec
Genetic relationship between placental and fetal weights and markers of the metabolic syndrome in rat recombinant inbred strains.
Physiological genomics 2006;26(3):226-31.
2006: Petr Dzubák; Marián Hajdúch; Radek Gazák; Alena Svobodová; Jitka Psotová; Daniela Walterová; Petr Sedmera; Vladimír Kren
New derivatives of silybin and 2,3-dehydrosilybin and their cytotoxic and P-glycoprotein modulatory activity.
Bioorganic & medicinal chemistry 2006;14(11):3793-810.
2006: Ondrej Seda; Ludmila Kazdová; Lucie Sedová; Frantisek Liska; Drahomíra Krenová; Vladimír Kren
Region of rat chromosome 8 determines complex nutrigenetic interactions under conditions of sucrose and cholesterol diets.
Prague medical report 2006;107(2):251-60.
2005: Martina Plísková; Jan Vondrácek; Vladimír Kren; Radek Gazák; Petr Sedmera; Daniela Walterová; Jitka Psotová; Vilím Simánek; Miroslav Machala
Effects of silymarin flavonolignans and synthetic silybin derivatives on estrogen and aryl hydrocarbon receptor activation.
Toxicology 2005;215(1-2):80-9.
2005: Vladimír Kren; Daniela Walterová
Silybin and silymarin--new effects and applications.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2005;149(1):29-41.
2005: Michal Pravenec; Vladimír Kren
Genetic analysis of complex cardiovascular traits in the spontaneously hypertensive rat.
Experimental physiology 2005;90(3):273-6.
2005: Ondrej Seda; Frantisek Liska; Drahomira Krenova; Ludmila Kazdova; Lucie Sedova; Tomáš Zima; Junzheng Peng; Kveta Pelinkova; Johanne Tremblay; Pavel Hamet; Vladimír Kren
Dynamic genetic architecture of metabolic syndrome attributes in the rat.
Physiological genomics 2005;21(2):243-52.
2005: Norbert Hubner; Caroline A Wallace; Heike Zimdahl; Enrico Petretto; Herbert Schulz; Fiona Maciver; Michael Mueller; Oliver Hummel; Jan Monti; Vaclav Zidek; Alena Musilova; Vladimír Kren; Helen C Causton; Laurence Game; Gabriele Born; Sabine Schmidt; Anita Müller; Stuart A Cook; theodore kurtz; John Whittaker; Michal Pravenec; Timothy J Aitman
Integrated transcriptional profiling and linkage analysis for identification of genes underlying disease.
Nature genetics 2005;37(3):243-53.
2005: Veronika Kristová; Ludmila Martínková; Lucie Husáková; Marek Kuzma; Jana Rauvolfová; Daniel Kavan; Petr Pompach; Karel Bezouska; Vladimír Kren
A chemoenzymatic route to mannosamine derivatives bearing different N-acyl groups.
Journal of biotechnology 2005;115(2):157-66.
2005: Ondrej Seda; Frantisek Liska; Lucie Sedová; Ludmila Kazdová; Drahomíra Krenová; Vladimír Kren
A 14-gene region of rat chromosome 8 in SHR-derived polydactylous congenic substrain affects muscle-specific insulin resistance, dyslipidaemia and visceral adiposity.
Folia biologica 2005;51(3):53-61.
2004: Zuzana Jirsová; Tomás Kucera; Jindrich Martínek; Frantisek Liska; Drahomíra Krenová; Vladimír Kren
Altered spermatogenesis in the hypodactylous rats.
Biomedical papers of the Medical Faculty of the University Palacký, Olomouc, Czechoslovakia 2004;148(2):213-5.
2004: Ondrej Plíhal; Jan Sklenár; J Kmonícková; Petr Man; Petr Pompach; Vladimír Havlícek; Vladimír Kren; Karel Bezouska
N-glycosylated catalytic unit meets O-glycosylated propeptide: complex protein architecture in a fungal hexosaminidase.
Biochemical Society transactions 2004;32(Pt 5):764-5.
2004: Radek Gazák; Alena Svobodová; Jitka Psotová; Petr Sedmera; Vera Prikrylová; Daniela Walterová; Vladimír Kren
Oxidised derivatives of silybin and their antiradical and antioxidant activity.
Bioorganic & medicinal chemistry 2004;12(21):5677-87.
2004: Daniela Monti; Andrea Pisvejcová; Vladimír Kren; Marco Lama; Sergio Riva
Generation of an alpha-L-rhamnosidase library and its application for the selective derhamnosylation of natural products.
Biotechnology and bioengineering 2004;87(6):763-71.
2004: L Sedova; Ondrej Seda; Drahomira Krenova; Vladimír Kren; Ludmila Kazdova
Isotretinoin and fenofibrate induce adiposity with distinct effect on metabolic profile in a rat model of the insulin resistance syndrome.
International journal of obesity and related metabolic disorders : journal of the International Association for the Study of Obesity 2004;28(5):719-25.
2004: Pavel Krist; Luca Vannucci; Marek Kuzma; Petr Man; Kashinath Sadalapure; Anupama Patel; Karel Bezouska; Miloslav Pospísil; Ladislav Petrus; Thisbe K Lindhorst; Vladimír Kren
Fluorescent labelled thiourea-bridged glycodendrons.
Chembiochem : a European journal of chemical biology 2004;5(4):445-52.
2004: Kristina Jenett-Siems; Inga Köhler; Carola Kraft; Heinz H Pertz; Vladimír Kren; Anna Fiserová; Marek Kuzma; Jitka Ulrichová; Ulrich Bienzle; Eckart Eich
In vitro antiplasmodial activities of semisynthetic N,N'-spacer-linked oligomeric ergolines.
Bioorganic & medicinal chemistry 2004;12(4):817-24.
2004: Robert Di Nicolantonio; Vladimír Kren; Vaclav Zidek; Michal Pravenec
Salt preference of congenic strains derived from the spontaneously hypertensive rat.
Physiology & behavior 2004;80(5):617-22.
2004: Frantisek Liska; Claudia Gösele; Vladimír Kren; Norbert Hübner; Drahomíra Krenová
Molecular analysis of the sex hormone-binding globulin gene in the rat hypodactylous mutation (Hd).
Folia biologica 2004;50(2):63-8.
2004: Michal Pravenec; Václav Zídek; Vladimir Landa; Miroslava Simáková; Petr Mlejnek; Ludmila Kazdová; Vlasta Bílá; Drahomíra Krenová; Vladimír Kren
Genetic analysis of "metabolic syndrome" in the spontaneously hypertensive rat.
Physiological research / Academia Scientiarum Bohemoslovaca 2004;53 Suppl 1():S15-22.
2004: Vladimír Kren; Eckart Eich; Heinz H Pertz
Pergolide, terguride and N,N'-spacer-linked oligomers of both interact with 5-HT2A receptors of rat tail artery.
Physiological research / Academia Scientiarum Bohemoslovaca 2004;53(1):35-43.
2003: Petr Mlejnek; Vladimír Kren; Frantisek Liska; Václav Zídek; Vladimir Landa; theodore kurtz; Michal Pravenec
The CD36 protein functions as an immunogenic domain of the RT8 alloantigen.
European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics 2003;30(5):325-7.
2003: Anita C M Bonné; Claudia Gösele; Maria G den Bieman; Gert F Gillissen; Thomas Kreitler; Michal Pravenec; Vladimír Kren; Hein A van Lith; Bert F M van Zutphen
Sequencing and chromosomal localization of Fabp6 and an intronless Fabp6 segment in the rat.
Molecular biology reports 2003;30(3):173-6.
2003: Jirí Pavlícek; Bruno Sopko; Rüdiger Ettrich; Vladimír Kopecký; Vladimír Baumruk; Petr Man; Vladimír Havlícek; Marek Vrbacký; Ludmila Martínková; Vladimír Kren; Miloslav Pospísil; Karel Bezouska
Molecular characterization of binding of calcium and carbohydrates by an early activation antigen of lymphocytes CD69.
Biochemistry 2003;42(31):9295-306.
2003: Martin Jirout; Drahomíra Krenová; Vladimír Kren; Laura Breen; Michal Pravenec; Nicholas J Schork; Morton P Printz
A new framework marker-based linkage map and SDPs for the rat HXB/BXH strain set.
Mammalian genome : official journal of the International Mammalian Genome Society 2003;14(8):537-46.
2003: Luca Vannucci; Anna Fiserová; Kashinath Sadalapure; Thisbe K Lindhorst; Markéta Kuldová; Pavel Rossmann; Ondrej Horváth; Vladimír Kren; Pavel Krist; Karel Bezouska; Martina Luptovcová; Franco Mosca; Miloslav Pospísil
Effects of N-acetyl-glucosamine-coated glycodendrimers as biological modulators in the B16F10 melanoma model in vivo.
International journal of oncology 2003;23(2):285-96.
2003: Morton P Printz; Martin Jirout; Rebecca Jaworski; Adamu Alemayehu; Vladimír Kren
Genetic Models in Applied Physiology. HXB/BXH rat recombinant inbred strain platform: a newly enhanced tool for cardiovascular, behavioral, and developmental genetics and genomics.
Journal of applied physiology (Bethesda, Md. : 1985) 2003;94(6):2510-22.
2003: Zdenka Pausova; Lucie Sedova; Julie Berube; Pavel Hamet; Johanne Tremblay; Marc Dumont; Daniel Gaudet; Michal Pravenec; Vladimír Kren; Jaroslav Kunes
Segment of rat chromosome 20 regulates diet-induced augmentations in adiposity, glucose intolerance, and blood pressure.
Hypertension 2003;41(5):1047-55.
2003: Lenka Weignerová; Petra Vavrusková; Andrea Pisvejcová; Joachim Thiem; Vladimír Kren
Fungal beta-N-acetylhexosaminidases with high beta-N-acetylgalactosaminidase activity and their use for synthesis of beta-GalNAc-containing oligosaccharides.
Carbohydrate research 2003;338(9):1003-8.
2003: Anita C M Bonné; Maria G den Bieman; Gert F Gillissen; Vladimír Kren; Drahomíra Krenová; Vlasta Bílá; Václav Zídek; Vlastimil Kostka; Alena Musilová; Michal Pravenec; Bert F M van Zutphen; Hein A van Lith
Genetic map of AFLP markers in the rat (Rattus norvegicus) derived from the H x B/Ipcv and B x H/Cub sets of recombinant inbred strains.
Biochemical genetics 2003;41(3-4):77-89.
2003: Ondrej Seda; Ludmila Kazdova; Drahomira Krenova; Vladimír Kren
Rosiglitazone fails to improve hypertriglyceridemia and glucose tolerance in CD36-deficient BN.SHR4 congenic rat strain.
Physiological genomics 2003;12(2):73-8.
2003: Ingeborg D de Wolf; Xandra M Fielmich-Bouman; Aegidius Lankhorst; Bernard A van Oost; Anton C Beynen; Vladimír Kren; Michal Pravenec; Bert F M van Zutphen; Hein A van Lith
Liver copper content of rats hypo- or hyperresponsive to dietary cholesterol.
Journal of trace elements in medicine and biology : organ of the Society for Minerals and Trace Elements (GMS) 2003;17(3):177-82.
2003: Ondrej Seda; Frantisek Liska; Drahomíra Krenová; Ludmila Kazdová; Lucie Sedová; Tomáš Zima; J Peng; Johanne Tremblay; Vladimír Kren; Pavel Hamet
Differential linkage of triglyceride and glucose levels on rat chromosome 4 in two segregating rat populations.
Folia biologica 2003;49(6):223-6.
2003: David Kemlink; V Jerábková; M Janků; Drahomíra Krenová; Vladimír Kren
PXO set of recombinant inbred strains of the rat: a new strain distribution pattern containing 448 markers.
Folia biologica 2003;49(4):165-76.
2003: P Simerská; Marek Kuzma; Andrea Pisvejcová; Lenka Weignerová; Martina Macková; Sergio Riva; Vladimír Kren
Application of selectively acylated glycosides for the alpha-galactosidase-catalyzed synthesis of disaccharides.
Folia microbiologica 2003;48(3):329-37.
2003: Michal Pravenec; Vladimír Kren; Drahomíra Krenová; Václav Zídek; Miroslava Simáková; Alena Musilová; J Vorlícek; E St Lezin; theodore kurtz
Genetic isolation of quantitative trait loci for blood pressure development and renal mass on chromosome 5 in the spontaneously hypertensive rat.
Physiological research / Academia Scientiarum Bohemoslovaca 2003;52(3):285-9.
2003: Johanne Tremblay; David Hum; Rocio Sanchez; Pierre Dumas; Michal Pravenec; Drahomira Krenova; Vladimír Kren; Jaroslav Kunes; Zdenka Pausova; Francis Gossard; Pavel Hamet
TA repeat variation, Npr1 expression, and blood pressure: impact of the Ace locus.
Hypertension 2003;41(1):16-24.
2002: Nianning Qi; Ludmila Kazdova; Vaclav Zidek; Vladimir Landa; Vladimír Kren; Harrihar A Pershadsingh; Elizabeth St Lezin; Nada A Abumrad; Michal Pravenec; theodore kurtz
Pharmacogenetic evidence that cd36 is a key determinant of the metabolic effects of pioglitazone.
The Journal of biological chemistry 2002;277(50):48501-7.
2002: Michal Pravenec; Václav Zídek; Alena Musilová; Miroslava Simáková; Vlastimil Kostka; Petr Mlejnek; Vladimír Kren; Drahomira Krenova; Vlasta Bílá; Blanka Míková; Marie Jáchymová; Karel Horký; Ludmila Kazdová; Elizabeth St Lezin; theodore kurtz
Genetic analysis of metabolic defects in the spontaneously hypertensive rat.
Mammalian genome : official journal of the International Mammalian Genome Society 2002;13(5):253-8.
2002: Pavel Kosina; Vladimír Kren; Rolf Gebhardt; Frantisek Grambal; Jitka Ulrichová; Daniela Walterová
Antioxidant properties of silybin glycosides.
Phytotherapy research : PTR 2002;16 Suppl 1():S33-9.
2002: Rebecca L Jaworski; Martin Jirout; Shamara Closson; Laura Breen; Pamela Flodman; M Anne Spence; Vladimír Kren; Drahomira Krenova; Michal Pravenec; Morton P Printz
Heart rate and blood pressure quantitative trait loci for the airpuff startle reaction.
Hypertension 2002;39(2 Pt 2):348-52.
2002: Pierre Dumas; Vladimír Kren; Drahomíra Krenová; Michal Pravenec; Pavel Hamet; Johanne Tremblay
Identification and chromosomal localization of ecogenetic components of electrolyte excretion.
Journal of hypertension 2002;20(2):209-17.
2002: Vladimír Kren; Anna Fiserová; Lenka Weignerová; Ivan Stibor; Petr Halada; Vera Prikrylová; Petr Sedmera; Miloslav Pospísil
Clustered ergot alkaloids modulate cell-mediated cytotoxicity.
Bioorganic & medicinal chemistry 2002;10(2):415-24.
2002: Monica Casali; Letizia Tarantini; Sergio Riva; Zdenka Hunkova; Lenka Weignerova; Vladimír Kren
Exploitation of a library of alpha-galactosidases for the synthesis of building blocks for glycopolymers.
Biotechnology and bioengineering 2002;77(1):105-10.
2002: Ondrej Seda; Ludmila Kazdová; Drahomíra Krenová; Vladimír Kren
Rosiglitazone improves insulin resistance, lipid profile and promotes adiposity in a genetic model of metabolic syndrome X.
Folia biologica 2002;48(6):237-41.
2002: Frantisek Liska; Göran Levan; Khalil Helou; M Sladká; Michal Pravenec; Václav Zídek; Vladimir Landa; Vladimír Kren
Chromosome assignment of Cd36 transgenes in two rat SHR lines by FISH and linkage mapping of transgenic insert in the SHR-TG19 line.
Folia biologica 2002;48(4):139-44.
2002: Ondrej Seda; Lucie Sedová; Ludmila Kazdová; Drahomíra Krenová; Vladimír Kren
Metabolic characterization of insulin resistance syndrome feature loci in three brown Norway-derived congenic strains.
Folia biologica 2002;48(3):81-8.
2002: Edita Bielavská; Vladimír Kren; Alena Musilová; Václav Zídek; Michal Pravenec
Genome scanning of the HXB/BXH sets of recombinant inbred strains of the rat for quantitative trait loci associated with conditioned taste aversion.
Behavior genetics 2002;32(1):51-6.
2002: Nicolas Solban; Pierre Dumas; Francis Gossard; Y Sun; Michal Pravenec; Vladimír Kren; Richard Z Lewanczuk; Pavel Hamet; Johanne Tremblay
Chromosomal mapping of HCaRG, a novel hypertension-related, calcium-regulated gene.
Folia biologica 2002;48(1):9-14.
2001: Ingeborg D de Wolf; Xandra M Fielmich-Bouman; Bernard A van Oost; Anton C Beynen; Vladimír Kren; Michal Pravenec; L F M van Zutphen; Hein A van Lith
Genetic and correlation analysis of hepatic copper content in the rat.
Biochemical and biophysical research communications 2001;289(5):1247-51.
2001: Ludmila Martínková; Vladimír Kren; L Cvak; M Ovesná; I Prepechalová
Hydrolysis of lysergamide to lysergic acid by Rhodococcus equi A4.
Journal of biotechnology 2001;84(1):63-6.
2001: T Semenuk; Pavel Krist; Jirí Pavlícek; Karel Bezouska; Marek Kuzma; Petr Novák; Vladimír Kren
Synthesis of chitooligomer-based glycoconjugates and their binding to the rat natural killer cell activation receptor NKR-P1.
Glycoconjugate journal 2001;18(10):817-26.
2001: Pavel Krist; E Herkommerová-Rajnochová; Jana Rauvolfová; T Semenuk; P Vavrusková; Jirí Pavlícek; Karel Bezouska; Ladislav Petrus; Vladimír Kren
Toward an optimal oligosaccharide ligand for rat natural killer cell activation receptor NKR-P1.
Biochemical and biophysical research communications 2001;287(1):11-20.
2001: Vladimír Kren; Ludmila Martínková
Glycosides in medicine: "The role of glycosidic residue in biological activity".
Current medicinal chemistry 2001;8(11):1303-28.
2001: Lenka Weignerová; Jaroslav Spizek; L Najmanová; Vladimír Kren
Enzymatic glycosylation of lincomycin.
Bioscience, biotechnology, and biochemistry 2001;65(8):1897-9.
2001: Michal Pravenec; Václav Zídek; Alena Musilová; J Vorlícek; Vladimír Kren; E St Lezin; theodore kurtz
Genetic isolation of a blood pressure quantitative trait locus on chromosome 2 in the spontaneously hypertensive rat.
Journal of hypertension 2001;19(6):1061-4.
2001: Michal Pravenec; Petr Jansa; Vlastimil Kostka; Václav Zídek; Vladimír Kren; Jiri Forejt; theodore kurtz
Identification of a mutation in ADD1/SREBP-1 in the spontaneously hypertensive rat.
Mammalian genome : official journal of the International Mammalian Genome Society 2001;12(4):295-8.
2001: Vladimír Kren; Nianning Qi; Drahomira Krenova; Vaclav Zidek; M Sladká; Marie Jáchymová; Blanka Míková; K Horky; A Bonne; Hein A van Lith; Bert F M van Zutphen; Y F Lau; Michal Pravenec; Elizabeth St Lezin
Y-chromosome transfer induces changes in blood pressure and blood lipids in SHR.
Hypertension 2001;37(4):1147-52.
2001: L Husáková; Sergio Riva; Monica Casali; S Nicotra; Marek Kuzma; Z Hunková; Vladimír Kren
Enzymatic glycosylation using 6-O-acylated sugar donors and acceptors: beta-N-acetylhexosaminidase-catalysed synthesis of 6-O,N,N'-triacetylchitobiose and 6'-O,N,N'-triacetylchitobiose.
Carbohydrate research 2001;331(2):143-8.
2001: I Prepechalová; Ludmila Martínková; A Stolz; M Ovesná; Karel Bezouska; J Kopecký; Vladimír Kren
Purification and characterization of the enantioselective nitrile hydratase from Rhodococcus equi A4.
Applied microbiology and biotechnology 2001;55(2):150-6.
2001: Vilím Simánek; Daniela Walterová; Jaroslav Vicar; J Urbaníková; Vladimír Kren; Martin Modrianský; Nina Skottová; Jitka Ulrichová
["Silymarin"--an extract from the milk thistle (Silybum marianum)--is it a drug or nutritional supplement?].
Ceská a Slovenská farmacie : casopis Ceské farmaceutické spolecnosti a Slovenské farmaceutické spolecnosti 2001;50(2):66-9.
2001: Pavel Hamet; Nathalie Thorin-Trescases; Pierre Moreau; Pierre Dumas; Bun-Seng Tea; Denis deBlois; Vladimír Kren; Michal Pravenec; Jaroslav Kunes; Y Sun; Johanne Tremblay
Workshop: excess growth and apoptosis: is hypertension a case of accelerated aging of cardiovascular cells?
Hypertension 2001;37(2 Pt 2):760-6.
2001: Michal Pravenec; Vladimir Landa; Vaclav Zidek; Alena Musilova; Vladimír Kren; Ludmila Kazdova; Timothy J Aitman; Anne M Glazier; Azeddine Ibrahimi; Nada A Abumrad; Nianning Qi; Jia-Ming Wang; Elizabeth St Lezin; theodore kurtz
Transgenic rescue of defective Cd36 ameliorates insulin resistance in spontaneously hypertensive rats.
Nature genetics 2001;27(2):156-8.
2001: Miloslav Pospisil; Luca Vannucci; Anna Fiserova; K Krausova; Ondrej Horvath; Vladimír Kren; Franco Mosca; Thisbe K Lindhorst; Kashinath Sadalapure; Karel Bezouska
Glycodendrimeric ligands of c-type lectin receptors as therapeutic agents in experimental cancer.
Advances in experimental medicine and biology 2001;495():343-7.
2000: Vladimír Kren; Jitka Ulrichová; Pavel Kosina; D Stevenson; Petr Sedmera; Vera Prikrylová; Petr Halada; Vilím Simánek
Chemoenzymatic preparation of silybin beta-glucuronides and their biological evaluation.
Drug metabolism and disposition: the biological fate of chemicals 2000;28(12):1513-7.
2000: Vilím Simánek; Vladimír Kren; Jitka Ulrichová; Jaroslav Vicar; L Cvak
Silymarin: What is in the name...? An appeal for a change of editorial policy.
Hepatology (Baltimore, Md.) 2000;32(2):442-4.
2000: Michal Pravenec; Vaclav Zidek; Alena Musilova; Vladimír Kren; Vlasta Bila; Robert Di Nicolantonio
Chromosomal mapping of a major quantitative trait locus regulating compensatory renal growth in the rat.
Journal of the American Society of Nephrology : JASN 2000;11(7):1261-5.
2000: Pierre Dumas; Y Sun; G Corbeil; S Tremblay; Zdenka Pausova; Vladimír Kren; Drahomira Krenova; Michal Pravenec; Pavel Hamet; Johanne Tremblay
Mapping of quantitative trait loci (QTL) of differential stress gene expression in rat recombinant inbred strains.
Journal of hypertension 2000;18(5):545-51.
2000: Pierre Dumas; Zdenka Pausová; Vladimír Kren; Drahomíra Krenová; Michal Pravenec; Marc Dumont; D Ely; M Turner; Y Sun; Johanne Tremblay; Pavel Hamet
Contribution of autosomal loci and the Y chromosome to the stress response in rats.
Hypertension 2000;35(2):568-73.
2000: J Dvoráková; Jan Kopecký; Vladimír Havlícek; Vladimír Kren
Formation of myo-inositol phosphates by Aspergillus niger 3-phytase.
Folia microbiologica 2000;45(2):128-32.
2000: V Bíla; Vladimír Kren; Frantisek Liska
The influence of the genetic background on the interaction of retinoic acid with Lx mutation of the rat.
Folia biologica 2000;46(6):264-72.
2000: Michal Pravenec; Václav Zídek; Vladimir Landa; Vlastimil Kostka; Alena Musilová; Ludmila Kazdová; A Fucíková; Drahomíra Krenová; V Bíla; Vladimír Kren
Genetic analysis of cardiovascular risk factor clustering in spontaneous hypertension.
Folia biologica 2000;46(6):233-40.
2000: Lucie Sedová; Ludmila Kazdová; Ondrej Seda; Drahomíra Krenová; Vladimír Kren
Rat inbred PD/cub strain as a model of dyslipidemia and insulin resistance.
Folia biologica 2000;46(3):99-106.
2000: Vladimír Kren; Miroslava Simáková; Alena Musilová; Václav Zídek; Michal Pravenec
SHR.BN-congenic strains for genetic analysis of multifactorially determined traits.
Folia biologica 2000;46(1):25-9.
2000: E St Lezin; W Liu; Jia-Ming Wang; Y Yang; Nianning Qi; Vladimír Kren; Vaclav Zidek; theodore kurtz; Michal Pravenec
Genetic analysis of rat chromosome 1 and the Sa gene in spontaneous hypertension.
Hypertension 2000;35(1 Pt 2):225-30.
1999: E St Lezin; Karen A Griffin; Maria M Picken; Monique C Churchill; Paul C Churchill; theodore kurtz; W Liu; N Wang; Vladimír Kren; Vaclav Zidek; Michal Pravenec; Anil K Bidani
Genetic isolation of a chromosome 1 region affecting susceptibility to hypertension-induced renal damage in the spontaneously hypertensive rat.
Hypertension 1999;34(2):187-91.
1999: Václav Zídek; J Pintír; Alena Musilová; Vlasta Bílá; Vladimír Kren; Michal Pravenec
Mapping of quantitative trait loci for seminal vesicle mass and litter size to rat chromosome 8.
Journal of reproduction and fertility 1999;116(2):329-33.
1999: Michal Pravenec; Vaclav Zidek; Miroslava Simakova; Vladimír Kren; Drahomira Krenova; K Horky; M Jachymova; Blanka Mikova; Ludmila Kazdova; Timothy J Aitman; Paul C Churchill; R Clinton Webb; N H Hingarh; Y Yang; Jia-Ming Wang; E M Lezin; theodore kurtz
Genetics of Cd36 and the clustering of multiple cardiovascular risk factors in spontaneous hypertension.
The Journal of clinical investigation 1999;103(12):1651-7.
1999: Zdenka Pausova; Jaroslav Kunes; Vladimír Kren; Drahomira Krenova; Michal Pravenec; Johanne Tremblay; Pavel Hamet
Contribution of the TNF alpha gene region of rat chromosome 20 to the body temperature response to endotoxin.
Transplantation proceedings 1999;31(3):1622-3.
1999: Drahomíra Krenová; Michal Pravenec; Daniel Housa; Frantisek Liska; Vlasta Bílá; R Kaspárek; Vladimír Kren
Linkage mapping of rat hypodactyly locus to chromosome 10.
Transplantation proceedings 1999;31(3):1620.
1999: Vladimír Kren; Michal Pravenec; Vlasta Bílá; Drahomíra Krenová; Václav Zídek; Miroslava Simáková; Morton P Printz
Rat congenic and recombinant inbred strains: a genetic model for the study of quantitative trait loci.
Transplantation proceedings 1999;31(3):1592-3.
1999: A Panczak; Vladimír Kren; Vlasta Bílá; Michal Pravenec; M Matousková; Drahomíra Krenová; Berta Otová; M Sladká
Graft-versus-host disease in the rat: a genetic analysis in recombinant inbred strains of SHR x BN. Lx and BN. Lx x SHR sets.
Transplantation proceedings 1999;31(3):1569-70.
1999: Michal Pravenec; Drahomíra Krenová; Vladimír Kren; Václav Zídek; Miroslava Simáková; Alena Musilová; A Bottger; Bert F M van Zutphen; E St Lezin; theodore kurtz
Congenic strains for genetic analysis of hypertension and dyslipidemia in the spontaneously hypertensive rat.
Transplantation proceedings 1999;31(3):1555-6.
1999: Václav Zídek; A Fucíková; Alena Musilová; Vlasta Bílá; Vladimír Kren; Michal Pravenec
Hematocrit and hemoglobin values are negatively correlated with insulin resistance in spontaneous hypertension.
Folia biologica 1999;45(6):247-51.
1999: Zdenka Pausova; Jaroslav Kunes; Vladimír Kren; Drahomíra Krenová; Michal Pravenec; Johanne Tremblay; Pavel Hamet
Endotoxin response in spontaneously hypertensive rats: a role of the TNFalpha-gene region.
Folia biologica 1999;45(1):3-6.
1999: Drahomíra Krenová; Zuzana Jirsová; Daniel Housa; Frantisek Liska; L Soltysová; R Kaspárek; Vlasta Bílá; Michal Pravenec; Vladimír Kren
Genetic analysis of the rat hypodactylous mutation.
Folia biologica 1999;45(3):81-6.
1999: Michal Pravenec; Vladimír Kren; Drahomíra Krenová; V Bíla; Václav Zídek; Miroslava Simáková; Alena Musilová; Hein A van Lith; L F M van Zutphen
HXB/Ipcv and BXH/Cub recombinant inbred strains of the rat: strain distribution patterns of 632 alleles.
Folia biologica 1999;45(5):203-15.
1999: E St Lezin; L Zhang; Y Yang; Jia-Ming Wang; N Wang; Nianning Qi; J S Steadman; W Liu; Vladimír Kren; Vaclav Zidek; Drahomira Krenova; Paul C Churchill; Monique C Churchill; Michal Pravenec
Effect of chromosome 19 transfer on blood pressure in the spontaneously hypertensive rat.
Hypertension 1999;33(1 Pt 2):256-60.
1999: Timothy J Aitman; Anne M Glazier; Caroline A Wallace; LD Cooper; Penny J Norsworthy; FN Wahid; K M Al-Majali; P M Trembling; Christopher J Mann; Carol C Shoulders; D Graf; E St Lezin; theodore kurtz; Vladimír Kren; Michal Pravenec; Azeddine Ibrahimi; Nada A Abumrad; L W Stanton; James Scott
Identification of Cd36 (Fat) as an insulin-resistance gene causing defective fatty acid and glucose metabolism in hypertensive rats.
Nature genetics 1999;21(1):76-83.
1998: Pavel Hamet; Zdenka Pausova; Pierre Dumas; Yu-Lin Sun; Johanne Tremblay; Michal Pravenec; Jaroslav Kunes; Drahomira Krenova; Vladimír Kren
Newborn and adult recombinant inbred strains: a tool to search for genetic determinants of target organ damage in hypertension.
Kidney international 1998;53(6):1488-92.
1998: Karel Bezouska; Vladimír Kren; C Kieburg; Thisbe K Lindhorst
GlcNAc-terminated glycodendrimers form defined precipitates with the soluble dimeric receptor of rat natural killer cells, sNKR-P1A.
FEBS letters 1998;426(2):243-7.
1998: Michal Pravenec; Václav Zídek; Miroslava Simáková; J Vorlícek; Vladimír Kren
Linkage mapping of the Fos cellular oncogene (Fos) to rat chromosome 6 and its possible role in the regulation of compensatory renal growth.
Folia biologica 1998;44(5):151-3.
1998: Sixtus Hynie; Vladimír Kren; M Mráz; Hassan Farghali
Phase I and phase II xenobiotic biotransformation in different inbred strains of rats: study in immobilized perfused hepatocytes.
Folia biologica 1998;44(4):127-32.
1998: Michal Pravenec; Vladimír Kren; M Hope; Jia-Ming Wang; E St Lezin
Linkage mapping of the interleukin 1beta converting enzyme (Il1bc) and the glutamate receptor subunit KA1 (Grik4) genes to rat chromosome 8.
Folia biologica 1998;44(3):107-9.
1998: E St Lezin; W Liu; N Wang; Jia-Ming Wang; Vladimír Kren; Vaclav Zidek; M Zdobinska; Drahomira Krenova; A Bottger; Bert F M van Zutphen; Michal Pravenec
Effect of renin gene transfer on blood pressure in the spontaneously hypertensive rat.
Hypertension 1998;31(1 Pt 2):373-7.
1997: Vladimír Kren; J Dvoráková; U Gambert; Petr Sedmera; Vladimír Havlícek; Joachim Thiem; Karel Bezouska
beta-Glucosylation of chitooligomers by galactosyltransferase.
Carbohydrate research 1997;305(3-4):517-23.
1997: E St Lezin; W Liu; Jia-Ming Wang; N Wang; Vladimír Kren; Drahomira Krenova; Alena Musilova; M Zdobinska; Vaclav Zidek; D Lau; Michal Pravenec
Genetic isolation of a chromosome 1 region affecting blood pressure in the spontaneously hypertensive rat.
Hypertension 1997;30(4):854-9.
1997: Paul C Churchill; Monique C Churchill; Anil K Bidani; Karen A Griffin; Maria M Picken; Michal Pravenec; Vladimír Kren; E St Lezin; Jia-Ming Wang; N Wang; theodore kurtz
Genetic susceptibility to hypertension-induced renal damage in the rat. Evidence based on kidney-specific genome transfer.
The Journal of clinical investigation 1997;100(6):1373-82.
1997: Karel Bezouska; Jan Sklenár; J Dvoráková; Vladimír Havlícek; Miloslav Pospísil; Joachim Thiem; Vladimír Kren
NKR-P1A protein, an activating receptor of rat natural killer cells, binds to the chitobiose core of uncompletely glycosylated N-linked glycans, and to linear chitooligomers.
Biochemical and biophysical research communications 1997;238(1):149-53.
1997: Michal Pravenec; Jiaming Wang; Vladimír Kren; E St Lezin
Linkage mapping of the mixed-lineage leukemia (Mll) gene to rat chromosome 8.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(8):625-6.
1997: Timothy J Aitman; T Gotoda; A L Evans; H Imrie; K E Heath; P M Trembling; H Truman; Caroline A Wallace; A Rahman; C Doré; J Flint; Vladimír Kren; Vaclav Zidek; theodore kurtz; Michal Pravenec; James Scott
Quantitative trait loci for cellular defects in glucose and fatty acid metabolism in hypertensive rats.
Nature genetics 1997;16(2):197-201.
1997: Michal Pravenec; Vladimír Kren; Jiaming Wang; theodore kurtz
Linkage mapping of the cellular retinoic acid-binding protein 1 (Crabp1) gene to rat chromosome 8.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(6):455-6.
1997: Michal Pravenec; Vaclav Zidek; M Zdobinska; Vladimír Kren; Drahomira Krenova; A Bottger; L F M van Zutphen; Jiaming Wang; E St Lezin
Mapping genes controlling hematocrit in the spontaneously hypertensive rat.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(6):387-9.
1997: Drahomíra Krenová; theodore kurtz; Jia-Ming Wang; Michal Pravenec; Vladimír Kren
Map of the differential segment of rat chromosome 8 in the SHR-Lx congenic strain.
Transplantation proceedings 1997;29(3):1769.
1997: Vladimír Kren; theodore kurtz; Drahomira Krenova; Vlasta Bila; Morton P Printz; Michal Pravenec
Rat genome mapping using recombinant inbred strains.
Transplantation proceedings 1997;29(3):1768.
1997: A Panczak; Vlasta Bílá; M Sladká; Drahomíra Krenová; Berta Otová; Michal Pravenec; Vladimír Kren
Genetic analysis of graft-versus-host disease using rat recombinant inbred strains.
Transplantation proceedings 1997;29(3):1734-5.
1997: Vlasta Bílá; Vladimír Kren
Retinoic acid teratogenicity in rat congenic and recombinant inbred strains with malformation syndrome.
Transplantation proceedings 1997;29(3):1707-8.
1997: Jiaming Wang; Michal Pravenec; Vladimír Kren; theodore kurtz
Linkage mapping of the Na-K-2Cl cotransporter gene (Slc12a1) to rat chromosome 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1997;8(5):379.
1997: Vladimír Kren; Michal Pravenec; S Lu; Drahomira Krenova; Jia-Ming Wang; N Wang; T Merriouns; A Wong; E St Lezin; D Lau; Claude Szpirer; J Szpirer; theodore kurtz
Genetic isolation of a region of chromosome 8 that exerts major effects on blood pressure and cardiac mass in the spontaneously hypertensive rat.
The Journal of clinical investigation 1997;99(4):577-81.
1997: Anna Fiserová; H Kovárů; Z Hajduová; Vladislav Mares; Miroslav Starec; Vladimír Kren; M Flieger
Neuroimmunomodulation of natural killer (NK) cells by ergot alkaloid derivatives.
Physiological research / Academia Scientiarum Bohemoslovaca 1997;46(2):119-25.
1997: Michal Pravenec; Vladimír Kren; Claude Szpirer; J Szpirer
Assignment of the cellular retinol binding protein 1 (Rbp1) and hepatic lipase (Lipc) genes to rat chromosome 8.
Folia biologica 1997;43(3):97-9.
1996: Pavel Hamet; M A Kaiser; Y Sun; V Pagé; M Vincent; Vladimír Kren; Michal Pravenec; Jaroslav Kunes; Johanne Tremblay; Nilesh J Samani
HSP27 locus cosegregates with left ventricular mass independently of blood pressure.
Hypertension 1996;28(6):1112-7.
1996: M Otsen; M den Bieman; Martin Kuiper; Michal Pravenec; Vladimír Kren; theodore kurtz; H J Jacob; A Lankhorst; Bert F M van Zutphen
Use of AFLP markers for gene mapping and QTL detection in the rat.
Genomics 1996;37(3):289-94.
1996: A Bottger; Hein A van Lith; Vladimír Kren; Drahomíra Krenová; Vlasta Bílá; J Vorlícek; Václav Zídek; Alena Musilová; M Zdobinská; Jia-Ming Wang; Bert F M van Zutphen; theodore kurtz; Michal Pravenec
Quantitative trait loci influencing cholesterol and phospholipid phenotypes map to chromosomes that contain genes regulating blood pressure in the spontaneously hypertensive rat.
The Journal of clinical investigation 1996;98(3):856-62.
1996: Michal Pravenec; Vladimír Kren; Jiaming Wang; A Bottger; L F M van Zutphen; theodore kurtz
Linkage mapping of the carboxyl ester lipase gene (Cel) to rat chromosome 3.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(7):559-60.
1996: Vladimír Kren; A Fiserová; C Augé; Petr Sedmera; Vladimír Havlícek; P Síma
Ergot alkaloid glycosides with immunomodulatory activities.
Bioorganic & medicinal chemistry 1996;4(6):869-76.
1996: Michal Pravenec; Dominique Gauguier; Jean-Jacques Schott; Jérôme Buard; Vladimír Kren; Vlasta Bílá; Claude Szpirer; J Szpirer; Jia-Ming Wang; H Huang; E St Lezin; M A Spence; Pamela Flodman; M Printz; G M Lathrop; Gilles Vergnaud; theodore kurtz
A genetic linkage map of the rat derived from recombinant inbred strains.
Mammalian genome : official journal of the International Mammalian Genome Society 1996;7(2):117-27.
1996: Vlasta Bílá; Vladimír Kren
The teratogenic action of retinoic acid in rat congenic and recombinant inbred strains.
Folia biologica 1996;42(4):167-73.
1996: Vladimír Kren; Vlasta Bílá; R Kaspárek; Drahomíra Krenová; Michal Pravenec; K Rapp
Recombinant inbred and congenic strains of the rat for genetic analysis of limb morphogenesis.
Folia biologica 1996;42(4):159-66.
1996: Vladimír Kren; Drahomíra Krenová; Vlasta Bílá; M Zdobinská; Václav Zídek; Michal Pravenec
Recombinant inbred and congenic strains for mapping of genes that are responsible for spontaneous hypertension and other risk factors of cardiovascular disease.
Folia biologica 1996;42(4):155-8.
1996: Michal Pravenec; Vladimír Kren; Vlasta Bílá; Drahomíra Krenová; M Zdobinská; theodore kurtz
Genetic linkage maps of the rat derived from an intercross and recombinant inbred strains originating from the BN.Lx and SHR progenitors.
Folia biologica 1996;42(4):147-53.
1995: H Huang; Michal Pravenec; Jia-Ming Wang; Vladimír Kren; E St Lezin; Claude Szpirer; J Szpirer; theodore kurtz
Mapping and sequence analysis of the gene encoding the beta subunit of the epithelial sodium channel in experimental models of hypertension.
Journal of hypertension 1995;13(11):1247-51.
1995: Michal Pravenec; Dominique Gauguier; Jean-Jacques Schott; Jérôme Buard; Vladimír Kren; V Bila; Claude Szpirer; J Szpirer; Jia-Ming Wang; H Huang
Mapping of quantitative trait loci for blood pressure and cardiac mass in the rat by genome scanning of recombinant inbred strains.
The Journal of clinical investigation 1995;96(4):1973-8.
1995: Vladimír Kren; Drahomíra Krenová; Michal Pravenec; M Zdobinská
Chromosome 8 congenic strains: tools for genetic analysis of limb malformation, plasma triglycerides, and blood pressure in the rat.
Folia biologica 1995;41(6):284-93.
1994: Pavel Hamet; Y L Sun; D Malo; D Kong; Vladimír Kren; Michal Pravenec; Jaroslav Kunes; P Dumas; L Richard; France Gagnon
Genes of stress in experimental hypertension.
Clinical and experimental pharmacology & physiology 1994;21(11):907-11.
1994: J Kunes; Vladimír Kren; Michal Pravenec; Josef Zicha
Use of recombinant inbred strains for evaluation of intermediate phenotypes in spontaneous hypertension.
Clinical and experimental pharmacology & physiology 1994;21(11):903-6.
1994: Vladimír Havlícek; Miroslav Flieger; Vladimír Kren; M Ryska
Fast atom bombardment mass spectrometry of elymoclavine glycosides.
Biological mass spectrometry 1994;23(2):57-60.
1994: Michal Pravenec; E St Lezin; Vladimír Kren; J M Wang; theodore kurtz
Linkage mapping of alkaline phosphatase 1, inhibin alpha subunit, and gamma-crystallin 1 on rat chromosome 9 and Na+, K(+)-ATPase alpha 2 subunit, renin, and leukocyte common antigen on rat chromosome 13.
Genomics 1994;19(1):190-1.
1994: Sixtus Hynie; Vladimír Kren; Vlasta Bílá; M Mráz; N Gaier; L Kameníková; Hassan Farghali
A preliminary evaluation of drug biotransformation in hepatocytes of genetically defined rat strains.
Physiological research / Academia Scientiarum Bohemoslovaca 1994;43(2):131-5.
1994: Vlasta Bílá; Vladimír Kren
Evidence for teratogenicity of thalidomide using congenic and recombinant inbred rat strains.
Folia biologica 1994;40(4):161-71.
1993: A Panczak; D Schlegerová; Michal Pravenec; Josef Stejskal; Vladimír Kren
Further study of the anti-TBM response in the spontaneously hypertensive rat using a panel of recombinant inbred strains.
Transplantation proceedings 1993;25(5):2828.
1993: Vladimír Kren; Berta Otová; Daniel Elleder; Milan Elleder; A Panczak; M Sladká
Model of acute graft-vs-host-disease in adult (SHR x BN.lx)F1 rats and its inhibition by adenine analog.
Transplantation proceedings 1993;25(5):2822-3.
1993: Drahomira Krenova; B Otova; Vladimír Kren
THY 1.1 and CD43 antigen expression on rat tumor cells.
Transplantation proceedings 1993;25(5):2797-8.
1993: Vladimír Kren; Michal Pravenec; V Bila; D Svobodova; E St Lezin; theodore kurtz
Linkage between the RT8 alloantigen and interleukin 6 loci on the rat chromosome 4.
Transplantation proceedings 1993;25(5):2777.
1993: A Vrána; Ludmila Kazdová; Zdenka Dobesová; J Kunes; Vladimír Kren; V Bílá; P Stolba; Iwar Klimes
Triglyceridemia, glucoregulation, and blood pressure in various rat strains. Effects of dietary carbohydrates.
Annals of the New York Academy of Sciences 1993;683():57-68.
1993: I Pohlová; Josef Zicha; Vladimír Kren; J Kunes; Michal Pravenec
Renal renin activity is associated with alterations of the renin gene in recombinant inbred rat strains.
Clinical science (London, England : 1979) 1993;84(2):129-32.
1993: Vladimír Kren; Berta Otová; Daniel Elleder; Milan Elleder; A Panczak; Antonín Holý
Prevention of acute graft-versus-host disease in rats using 9-(2-phosphonomethoxyethyl) adenine (PMEA).
Folia biologica 1993;39(2):78-86.
1993: Vlasta Bílá; Berta Otová; R Jelínek; M Sladká; B Mejsnarová; Antonín Holý; Vladimír Kren
Antimitotic and teratogenic effects of acyclic nucleotide analogues 1-(S)-(3-hydroxy-2-phosphonomethoxyethyl)cytosine (HPMPC) and 9-(2-phosphonomethoxyethyl) adenine (PMEA).
Folia biologica 1993;39(3):150-61.
1993: Berta Otová; M Sladká; Ivan Votruba; Antonín Holý; Vladimír Kren
Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). I. Lymphatic leukemia KHP-Lw-I in Lewis rats.
Folia biologica 1993;39(3):136-41.
1993: Berta Otová; Drahomíra Krenová; Zdenek Zídek; Antonín Holý; Ivan Votruba; Vladimír Kren
Cytostatic effect of 9-(2-phosphonomethoxyethyl) adenine (PMEA). III. Rat and mouse carcinomas and sarcomas.
Folia biologica 1993;39(6):311-4.
1992: Michal Pravenec; J Kunes; Josef Zicha; Vladimír Kren; P Klír
Platelet aggregation in spontaneous hypertension: genetic determination and correlation analysis.
Journal of hypertension 1992;10(12):1453-6.
1992: H K Talib; Zdenka Dobesová; P Klír; Vladimír Kren; J Kunes; Michal Pravenec; Josef Zicha
Association of red blood cell sodium leak with blood pressure in recombinant inbred strains.
Hypertension 1992;20(4):575-82.
1992: Pavel Hamet; D Kong; M Pravenec; Jaroslav Kunes; Vladimír Kren; P Klir; Y L Sun; Johanne Tremblay
Restriction fragment length polymorphism of hsp70 gene, localized in the RT1 complex, is associated with hypertension in spontaneously hypertensive rats.
Hypertension 1992;19(6 Pt 2):611-4.
1992: Michal Pravenec; L Simonet; Vladimír Kren; E St Lezin; G Levan; J Szpirer; Claude Szpirer; T Kurtz
Assignment of rat linkage group V to chromosome 19 by single-strand conformation polymorphism analysis of somatic cell hybrids.
Genomics 1992;12(2):350-6.
1992: Vlasta Bílá; Vladimír Kren
Teratogenicity testing based on the interaction with a mutant allele.
Folia biologica 1992;38(1):40-7.
1992: M Sladká; Kyra Michalová; J Hejnar; Michal Pravenec; Jiri Forejt; Vladimír Kren
In situ hybridization of a rat cDNA probe for glutathione S-transferase gene Ya subunit (GST Ya) to rat chromosome 8.
Folia biologica 1992;38(2):84-9.
1991: Michal Pravenec; Vladimír Kren; P Klír; L Simonet; T Kurtz
Identification of genes determining spontaneous hypertension. Review article.
Sborník lékar̆ský 1991;93(5-6):136-41.
1991: Michal Pravenec; L Simonet; Vladimír Kren; J Kunes; G Levan; J Szpirer; Claude Szpirer; T Kurtz
The rat renin gene: assignment to chromosome 13 and linkage to the regulation of blood pressure.
Genomics 1991;9(3):466-72.
1991: Michal Pravenec; Vladimír Kren; J Kunes; A Guillermo Scicli; Oscar Carretero; L Simonet; theodore kurtz
Cosegregation of blood pressure with a kallikrein gene family polymorphism.
Hypertension 1991;17(2):242-6.
1990: Vladimír Kren; Michal Pravenec; Vlasta Bílá; R Daniel; P Stursa; P Hĕvkovský; theodore kurtz
Genetic analysis of polydactyly-luxate syndrome in the rat.
Transplantation proceedings 1990;22(6):2588-9.
1990: A Panczak; D Schlegerová; Josef Stejskal; Vladimír Kren
Complex genetic determination of the antitubular basement membrane disease in the rat.
Transplantation proceedings 1990;22(6):2568-9.
1990: M Sladká; Vladimír Kren; Michal Pravenec
Question of homology between rat chromosome 8 and mouse chromosome 9.
Transplantation proceedings 1990;22(6):2563.
1990: Michal Pravenec; Vladimír Kren; Vlasta Bílá; P Kabra; M Krsiaková; L Simonet; theodore kurtz
HXB and BXH sets of recombinant inbred strains: strain distribution patterns of some genetic markers.
Transplantation proceedings 1990;22(6):2557-8.
1990: M Krsiaková; A Panczak; D Schlegerová; Josef Stejskal; Drahomíra Krenová; Vladimír Kren
Lewis kidney grafts in RT4- and/or RT6-incompatible recipients.
Transplantation proceedings 1990;22(6):2545-6.
1990: D Schlegerová; A Panczak; Josef Stejskal; Vladimír Kren
Anti-tubular basement membrane rejection nephropathy in rat kidney transplantation across multiple non-major histocompatibility complex alloantigenic differences.
Transplantation proceedings 1990;22(6):2539-40.
1990: Michal Pravenec; P Kabra; Vladimír Kren; L Simonet; theodore kurtz
Linkage between renin and fumarate hydratase genes in the rat.
Transplantation proceedings 1990;22(6):2555.
1990: J Kunes; Vladimír Kren; P Klír; Josef Zicha; Michal Pravenec
Genetic determination of heart and kidney weights studied using a set of recombinant inbred strains: the relationship to blood pressure.
Journal of hypertension 1990;8(12):1091-5.
1990: Vlasta Bílá; Vladimír Kren
The interaction of rat mutant allele lx with 5-azacytidine.
Transplantation proceedings 1990;22(6):2590.
1990: L Antalíková; Vladimír Kren; Vlasta Bílá; R Kaspárek
Contribution to the morphometry of limb bud structures in the normodactylous and polydactylous rat. II. Density of filopodia in the subectodermal zone.
Folia morphologica 1990;38(4):418-22.
1990: L Antalíková; Vladimír Kren; Vlasta Bílá; R Kaspárek; Jirí Rozinek
Contribution to the morphometry of limb bud structures in the normodactylous and polydactylous rat. I. Apical ectodermal ridge.
Folia morphologica 1990;38(4):402-7.
1989: Michal Pravenec; P Klír; Vladimír Kren; Josef Zicha; J Kunes
An analysis of spontaneous hypertension in spontaneously hypertensive rats by means of new recombinant inbred strains.
Journal of hypertension 1989;7(3):217-21.
1989: Frantisek Smíd; Vladimír Kren; V Bradová; Pavel Veselý; Drahomíra Krenová
Ganglioside composition in experimental tumors with different growth properties.
Neoplasma 1989;36(5):519-27.
1989: Pavel Veselý; H Melezínková; Drahomíra Krenová; Vladimír Kren; Eva Matousková; A Chaloupková
Spontaneously metastasizing rat sarcomas LW13K2 and RPS: assessment by the immunogenetic test of malignancy, in vitro behaviour and karyology.
Folia biologica 1989;35(1):1-12.
1989: L Antalíková; Vladimír Kren; R Kaspárek; Vlasta Bílá
Patterns of physiological cell death and mitoses in the apical ectodermal ridge in normodactylous and polydactylous rat limb buds. A quantitative evaluation.
Folia biologica 1989;35(5):339-46.
1988: Berta Otová; Vladimír Kren; Vlasta Bílá; A Bukovský
[Homology of class II antigens of the major histocompatibility complex in humans and rats].
Sborník lékar̆ský 1988;90(5):129-32.
1988: M Sladká; Vladimír Kren; P Klír
Spontaneous acute lymphoblastic leukemia in Sprague-Dawley rats. II. Cytogenetic analysis of nine individual leukemias.
Neoplasma 1988;35(4):379-88.
1988: A Myslivecková; L Antalíková; Vladimír Kren; Vlasta Bílá
Morphological analysis of apical structures of the limb bud of the laboratory rats in the polydactyly-luxate syndrome.
Folia morphologica 1988;36(1):32-7.
1988: Berta Otová; Vladimír Kren; M Sladká; P Klír
Spontaneous acute lymphoblastic leukemia in Sprague-Dawley rats. I. Immunogenetic analysis of four individual leukemias.
Neoplasma 1988;35(3):315-20.
1987: M Pravenec; Vladimír Kren; P Klír
Assignment of the Es-6 locus to linkage group VII of the rat (Rattus norvegicus) by the use of HXB recombinant inbred rat strains.
Journal of immunogenetics 1987;14(6):313-6.
1987: Drahomíra Krenová; Berta Otová; Vladimír Kren
Antigenic phenotype of LEW rat lymphatic leukemia.
Neoplasma 1987;34(2):139-49.
1987: Berta Otová; I Stefanová; Václav Horejsí; M Nĕmec; Vladimír Kren; V Viklický
HLA-DQ1 + DQ3-specific monoclonal antibody cross-reacts with a rat MHC-encoded polymorphic determinant.
Folia biologica 1987;33(6):424-9.
1987: Berta Otová; Vladimír Kren; A Bukovský; J Pospíchalová
The cross-reaction patterns of the MRC OX-3, OX-6, and OX-17 monoclonal antibodies on rat inbred and congenic strains.
Folia biologica 1987;33(5):363-6.
1986: L Kameníková; Zdenek Zídek; Evzen Buchar; Vladimír Kren; Drahomíra Krenová; I Janků
Study of relationship between allogeneic transplantability of tumors and their effects on drug-metabolizing system in rats.
Neoplasma 1986;33(1):21-5.
1985: A Panczak; Vladimír Kren; Josef Stejskal; D Schlegerová
Genetic analysis of anti-TBM disease in the Norway rat.
Folia biologica 1985;31(4):261-72.
1983: F Smid; Vladimír Kren; V Bradová
[Composition of gangliosides in experimental rat tumors].
Ceskoslovenská patologie 1983;19(3):149-53.
1983: P Panczak; Vladimír Kren; Josef Stejskal; D Schlegerová
[Immunogenetic conditions for the development of autoimmune tubulointerstitial nephritis (TIN) in rats (Rattus norvegicus)].
Sborník lékar̆ský 1983;85(5):129-32.
1983: A Panczak; Vladimír Kren; Josef Stejskal; D Schlegerová
MHC control of autoimmune anti-TBM reaction in the Norway rat.
Folia biologica 1983;29(5):337-48.
1981: Pavel Veselý; Vladimír Kren; P Urbanec; E Krchnáková
A contribution to the relationship between tumour cell social behaviour in vitro and malignancy in vivo.
Folia biologica 1981;27(2):140-7.
1980: Vlasta Bílá; Vladimír Kren; A Jirásek; R Kaspárek; P Hnĕvkovský
The morphology of the dominant polydactyly-luxate syndrome (DPLS) and the interaction of DPLS and PLS.
Folia morphologica 1980;28(1):39-44.
1980: Vladimír Kren; Vlasta Bílá; P Hnĕvkovský; R Kaspárek; H Patrná
Genetically controlled morphological variability of the polydactyly-luxate syndrome (PLS) of the Norway rat.
Folia morphologica 1980;28(1):28-38.