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Robert Kretsinger

Research Profile

Concepts & Ideas

Chemicals & Drugs

Genes & Molecular Sequences

Amino Acid Sequences

Procedures

X Ray Crystallography

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X-Ray Diffraction

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Publications

TOP 3
Lily Zhou; Jing Wu; Ronald Bauerle; Vijayalakshmi Janakiraman; Robert H Kretsinger; Igor A Shumilin; Ronald W Woodard
Structure and characterization of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Aeropyrum pernix.
Robert H Kretsinger
Neuronal calcium sensor proteins - recognizing a face in a crowd.
Norio Matsushima; Takanori Tanaka; Robert H Kretsinger
Non-globular structures of tandem repeats in proteins.

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All Publications

2012: Lily Zhou; Jing Wu; Ronald Bauerle; Vijayalakshmi Janakiraman; Robert H Kretsinger; Igor A Shumilin; Ronald W Woodard
Structure and characterization of the 3-deoxy-D-arabino-heptulosonate 7-phosphate synthase from Aeropyrum pernix.
Bioorganic chemistry 2012;40(1):79-86.
2012: Robert H Kretsinger
Neuronal calcium sensor proteins - recognizing a face in a crowd.
Frontiers in molecular neuroscience 2012;5():41.
2009: Norio Matsushima; Takanori Tanaka; Robert H Kretsinger
Non-globular structures of tandem repeats in proteins.
Protein and peptide letters 2009;16(11):1297-322.
2009: Eugene A Permyakov; Robert H Kretsinger
Cell signaling, beyond cytosolic calcium in eukaryotes.
Journal of inorganic biochemistry 2009;103(1):77-86.
2007: Alexander S Solodukhin; Robert H Kretsinger; Julianne J Sando
Initial three-dimensional reconstructions of protein kinase C delta from two-dimensional crystals on lipid monolayers.
Cellular signalling 2007;19(10):2035-45.
2006: Purevjav Enkhbayar; Kunio Hikichi; Mitsuru Osaki; Robert H Kretsinger; Norio Matsushima
3(10)-helices in proteins are parahelices.
Proteins 2006;64(3):691-9.
2005: Norio Matsushima; N Tachi; Y Kuroki; Purevjav Enkhbayar; Mitsuru Osaki; Masakatsu Kamiya; Robert H Kretsinger
Structural analysis of leucine-rich-repeat variants in proteins associated with human diseases.
Cellular and molecular life sciences : CMLS 2005;62(23):2771-91.
2005: Roger E Ison; Sven Hovmöller; Robert H Kretsinger
Proteins and their shape strings. An exemplary computer representation of protein structure.
IEEE engineering in medicine and biology magazine : the quarterly magazine of the Engineering in Medicine & Biology Society 2005;24(3):41-9.
2004: Igor A Shumilin; Ronald Bauerle; Jing Wu; Ronald W Woodard; Robert H Kretsinger
Crystal structure of the reaction complex of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Thermotoga maritima refines the catalytic mechanism and indicates a new mechanism of allosteric regulation.
Journal of molecular biology 2004;341(2):455-66.
2004: Robert H Kretsinger; Roger E Ison; Sven Hovmöller
Prediction of protein structure.
Methods in enzymology 2004;383():1-27.
2003: Igor A Shumilin; Ronald Bauerle; Robert H Kretsinger
The high-resolution structure of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase reveals a twist in the plane of bound phosphoenolpyruvate.
Biochemistry 2003;42(13):3766-76.
2003: Caroline Freye-Minks; Robert H Kretsinger; Carl E Creutz
Structural and dynamic changes in human annexin VI induced by a phosphorylation-mimicking mutation, T356D.
Biochemistry 2003;42(3):620-30.
2002: Igor A Shumilin; Chang Zhao; Ronald Bauerle; Robert H Kretsinger
Allosteric inhibition of 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase alters the coordination of both substrates.
Journal of molecular biology 2002;320(5):1147-56.
2002: Alexander S Solodukhin; Heather L Caldwell; Julianne J Sando; Robert H Kretsinger
Two-dimensional crystal structures of protein kinase C-delta, its regulatory domain, and the enzyme complexed with myelin basic protein.
Biophysical journal 2002;82(5):2700-8.
2002: Carl E Creutz; Sarina Mohanty; Tony Defalco; Robert H Kretsinger
Purine composition of the crystalline cytoplasmic inclusions of Paramecium tetraurelia.
Protist 2002;153(1):39-45.
2000: T Wagner; Igor A Shumilin; Ronald Bauerle; Robert H Kretsinger
Structure of 3-deoxy-d-arabino-heptulosonate-7-phosphate synthase from Escherichia coli: comparison of the Mn(2+)*2-phosphoglycolate and the Pb(2+)*2-phosphoenolpyruvate complexes and implications for catalysis.
Journal of molecular biology 2000;301(2):389-99.
2000: T Wagner; Robert H Kretsinger; Ronald Bauerle; WD Tolbert
3-Deoxy-D-manno-octulosonate-8-phosphate synthase from Escherichia coli. Model of binding of phosphoenolpyruvate and D-arabinose-5-phosphate.
Journal of molecular biology 2000;301(2):233-8.
2000: A J Avila-Sakar; Robert H Kretsinger; Carl E Creutz
Membrane-bound 3D structures reveal the intrinsic flexibility of annexin VI.
Journal of structural biology 2000;130(1):54-62.
2000: Norio Matsushima; T Ohyanagi; T Tanaka; Robert H Kretsinger
Super-motifs and evolution of tandem leucine-rich repeats within the small proteoglycans--biglycan, decorin, lumican, fibromodulin, PRELP, keratocan, osteoadherin, epiphycan, and osteoglycin.
Proteins 2000;38(2):210-25.
1999: Igor A Shumilin; Robert H Kretsinger; Ronald Bauerle
Crystal structure of phenylalanine-regulated 3-deoxy-D-arabino-heptulosonate-7-phosphate synthase from Escherichia coli.
Structure (London, England : 1993) 1999;7(7):865-75.
1999: WD Tolbert; S Chatterji; Ronald Bauerle; Robert H Kretsinger
Crystallization and preliminary crystallographic studies of the anthranilate synthase partial complex from Salmonella typhimurium.
Acta crystallographica. Section D, Biological crystallography 1999;55(Pt 1):305-6.
1998: Julianne J Sando; Olga Chertihin; J M Owens; Robert H Kretsinger
Contributions to maxima in protein kinase C activation.
The Journal of biological chemistry 1998;273(51):34022-7.
1998: A J Avila-Sakar; Carl E Creutz; Robert H Kretsinger
Crystal structure of bovine annexin VI in a calcium-bound state.
Biochimica et biophysica acta 1998;1387(1-2):103-16.
1998: J M Owens; Robert H Kretsinger; Julianne J Sando; Olga Chertihin
Two-dimensional crystals of protein kinase C.
Journal of structural biology 1998;121(1):61-7.
1996: H Kawasaki; A Avila-Sakar; Carl E Creutz; Robert H Kretsinger
The crystal structure of annexin VI indicates relative rotation of the two lobes upon membrane binding.
Biochimica et biophysica acta 1996;1313(3):277-82.
1994: S Raghunathan; R J Chandross; Robert H Kretsinger; Timothy Allison; C J Penington; Gordon S Rule
Crystal structure of human class mu glutathione transferase GSTM2-2. Effects of lattice packing on conformational heterogeneity.
Journal of molecular biology 1994;238(5):815-32.
1993: S Raghunathan; R J Chandross; B P Cheng; A Persechini; S E Sobottka; Robert H Kretsinger
The linker of des-Glu84-calmodulin is bent.
Proceedings of the National Academy of Sciences of the United States of America 1993;90(14):6869-73.
1993: Robert H Kretsinger; S Nakayama
Evolution of EF-hand calcium-modulated proteins. IV. Exon shuffling did not determine the domain compositions of EF-hand proteins.
Journal of molecular evolution 1993;36(5):477-88.
1993: S Nakayama; Robert H Kretsinger
Evolution of EF-hand calcium-modulated proteins. III. Exon sequences confirm most dendrograms based on protein sequences: calmodulin dendrograms show significant lack of parallelism.
Journal of molecular evolution 1993;36(5):458-76.
1992: Robert H Kretsinger
Calmodulin and myosin light chain kinase: how helices are bent.
Science (New York, N.Y.) 1992;258(5079):50-1.
1992: Robert H Kretsinger
The linker of calmodulin--to helix or not to helix.
Cell calcium 1992;13(6-7):363-76.
1992: S Nakayama; N D Moncrief; Robert H Kretsinger
Evolution of EF-hand calcium-modulated proteins. II. Domains of several subfamilies have diverse evolutionary histories.
Journal of molecular evolution 1992;34(5):416-48.
1992: S A Amero; Robert H Kretsinger; N D Moncrief; Keith R Yamamoto; W R Pearson
The origin of nuclear receptor proteins: a single precursor distinct from other transcription factors.
Molecular endocrinology (Baltimore, Md.) 1992;6(1):3-7.
1991: B L Gabriel; K Taylor; Carl E Creutz; Robert H Kretsinger
Microcrystals of the annexin, p68: paracrystal to crystal transition and molecular packing as determined by electron microscopy and image reconstruction.
Journal of structural biology 1991;107(1):29-37.
1991: A Persechini; Robert H Kretsinger; Trisha Davis
Calmodulins with deletions in the central helix functionally replace the native protein in yeast cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(2):449-52.
1990: N D Moncrief; Robert H Kretsinger; Morris Goodman
Evolution of EF-hand calcium-modulated proteins. I. Relationships based on amino acid sequences.
Journal of molecular evolution 1990;30(6):522-62.
1989: A Persechini; N D Moncrief; Robert H Kretsinger
The EF-hand family of calcium-modulated proteins.
Trends in neurosciences 1989;12(11):462-7.
1989: A Persechini; D K Blumenthal; Harry Jarrett; C B Klee; D O Hardy; Robert H Kretsinger
The effects of deletions in the central helix of calmodulin on enzyme activation and peptide binding.
The Journal of biological chemistry 1989;264(14):8052-8.
1989: Robert H Kretsinger; N D Moncrief
Evolution of calcium modulated proteins.
The Virginia explorer 1989;5(5):7-9.
1988: A Persechini; Robert H Kretsinger
The central helix of calmodulin functions as a flexible tether.
The Journal of biological chemistry 1988;263(25):12175-8.
1988: D O Hardy; P K Bender; Robert H Kretsinger
Two calmodulin genes are expressed in Arbacia punctulata. An ancient gene duplication is indicated.
Journal of molecular biology 1988;199(1):223-7.
1988: A Persechini; Robert H Kretsinger
Toward a model of the calmodulin-myosin light-chain kinase complex: implications for calmodulin function.
Journal of cardiovascular pharmacology 1988;12 Suppl 5():S1-12.
1987: J Vitali; William W Young; V B Schatz; S E Sobottka; Robert H Kretsinger
Crystal structure of an anti-Lewis alpha Fab determined by molecular replacement methods.
Journal of molecular biology 1987;198(2):351-5.
1986: Robert H Kretsinger; S E Rudnick; L J Weissman
Crystal structure of calmodulin.
Journal of inorganic biochemistry 1986;28(2-3):289-302.
1980: Robert H Kretsinger; S E Rudnick; D A Sneden; V B Schatz
Calmodulin, S-100, and crayfish sarcoplasmic calcium-binding protein crystals suitable for X-ray diffraction studies.
The Journal of biological chemistry 1980;255(17):8154-6.