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Hans Kretzschmar

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Kohji Mori; Kristin Rentzsch; Bettina Schmid; Christine Van Broeckhoven; Shih-Ming Weng; Christian Haass; Elisabeth Kremmer; Hans A Kretzschmar; Stephanie May; Thomas Arzberger; Marc Cruts; Dieter Edbauer
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
Kohji Mori; Manuela Neumann; Christine Van Broeckhoven; Sonja Zilow; Thomas Arzberger; Marc Cruts; Dieter Edbauer; Ignasi Forné; Jochen Herms; Jonathan Janssens; Gernot Kleinberger; Hans A Kretzschmar; Sven Lammich; Ian R A Mackenzie; Christian Haass
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations.
Julia Pöschl; Mario M Dorostkar; Daniel Grammel; Hans A Kretzschmar; Ulrich Schüller
Constitutive activation of β-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system.

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2013: Kohji Mori; Kristin Rentzsch; Bettina Schmid; Christine Van Broeckhoven; Shih-Ming Weng; Christian Haass; Elisabeth Kremmer; Hans A Kretzschmar; Stephanie May; Thomas Arzberger; Marc Cruts; Dieter Edbauer
The C9orf72 GGGGCC repeat is translated into aggregating dipeptide-repeat proteins in FTLD/ALS.
Science (New York, N.Y.) 2013;339(6125):1335-8.
2013: Kohji Mori; Manuela Neumann; Christine Van Broeckhoven; Sonja Zilow; Thomas Arzberger; Marc Cruts; Dieter Edbauer; Ignasi Forné; Jochen Herms; Jonathan Janssens; Gernot Kleinberger; Hans A Kretzschmar; Sven Lammich; Ian R A Mackenzie; Christian Haass
hnRNP A3 binds to GGGGCC repeats and is a constituent of p62-positive/TDP43-negative inclusions in the hippocampus of patients with C9orf72 mutations.
Acta neuropathologica 2013;125(3):413-23.
2013: Julia Pöschl; Mario M Dorostkar; Daniel Grammel; Hans A Kretzschmar; Ulrich Schüller
Constitutive activation of β-catenin in neural progenitors results in disrupted proliferation and migration of neurons within the central nervous system.
Developmental biology 2013;374(2):319-32.
2013: Annika Plate; Dan Rujescu; Elisabeth Wlasich; Jens Benninghoff; Kai Bötzel; Alexander Drzezga; Sabina Eigenbrod; Gerald H Jansen; Nathalie L Jansen; Hans A Kretzschmar; Adrian Danek
Atypical parkinsonism due to a D202N Gerstmann-Sträussler-Scheinker prion protein mutation: first in vivo diagnosed case.
Movement disorders : official journal of the Movement Disorder Society 2013;28(2):241-4.
2013: Gabi Schelzke; Katharina Stoeck; Sabina Eigenbrod; Eva Grasbon-Frodl; Hans A Kretzschmar; Claudia Ponto; Lena M Raddatz; Inga Zerr
Report about four novel mutations in the prion protein gene.
Dementia and geriatric cognitive disorders 2013;35(3-4):229-37.
2012: Nathalie L Jansen; Friedrich W Kreth; Hans A Kretzschmar; Christian la Fougère; Jürgen Lutz; Gabriele Pöpperl; Christoph Schwartz; Peter Bartenstein; Paul Cumming; Rupert Egensperger; Sabina Eigenbrod; Vera Graute; Jörg-Christian Tonn; Niklas Thon
Prediction of oligodendroglial histology and LOH 1p/19q using dynamic [(18)F]FET-PET imaging in intracranial WHO grade II and III gliomas.
Neuro-oncology 2012;14(12):1473-80.
2012: Tobias Bittner; Steffen Burgold; Mario M Dorostkar; Martin Fuhrmann; Hans A Kretzschmar; Boris Schmidt; Bettina M Wegenast-Braun; Jochen Herms
Amyloid plaque formation precedes dendritic spine loss.
Acta neuropathologica 2012;124(6):797-807.
2012: Pascal F Durrenberger; Peter Falkai; Francisca S Fernando; Isidro Ferrer; Peter J Gebicke-Haerter; Edna Grünblatt; Samira N Kashefi; Hans A Kretzschmar; Roberta Magliozzi; Brahim Nait-Oumesmar; Miklos Palkovits; Piero Parchi; Thomas Arzberger; Timothy P Bonnert; Sabina Capellari; David T Dexter; Federico Roncaroli; Andrea Schmitt; Danielle Seilhean; Richard Reynolds
Selection of novel reference genes for use in the human central nervous system: a BrainNet Europe Study.
Acta neuropathologica 2012;124(6):893-903.
2012: Manuela Neumann; Chiara F Valori; Osamu Yokota; David G Munoz; Lee Cyn Ang; Olaf Ansorge; Juan M Bilbao; Kenji Ishihara; Hans A Kretzschmar; Hirofumi Kusaka; Ian R A Mackenzie
Transportin 1 accumulates specifically with FET proteins but no other transportin cargos in FTLD-FUS and is absent in FUS inclusions in ALS with FUS mutations.
Acta neuropathologica 2012;124(5):705-16.
2012: S Alexandra Adam; Sabina Eigenbrod; Hans A Kretzschmar; Julia Pöschl; Oliver Schnell; Jörg-Christian Tonn; Ulrich Schüller
ALDH1A1 is a marker of astrocytic differentiation during brain development and correlates with better survival in glioblastoma patients.
Brain pathology (Zurich, Switzerland) 2012;22(6):788-97.
2012: Piero Parchi; Annemieke Rozemuller; Daniela Saverioni; Danielle Seilhean; Fabrizio Tagliavini; Mark L Cohen; Laura de Boni; Isidro Ferrer; Pierluigi Gambetti; Ellen Gelpi; Giorgio Giaccone; Armin Giese; JEAN-JACQUES HAUW; Romana Höftberger; James W Ironside; Casper Jansen; Gabor Geza Kovacs; Hans A Kretzschmar
Consensus classification of human prion disease histotypes allows reliable identification of molecular subtypes: an inter-rater study among surveillance centres in Europe and USA.
Acta neuropathologica 2012;124(4):517-29.
2012: Theo F J Kraus; Thomas Carell; Sabina Eigenbrod; Wolfgang Feiden; Daniel Globisch; Benjamin Hackner; Markus Müller; Martin Münzel; Toni Pfaffeneder; Ulrich Schüller; Mirko Wagner; David Widmann; Hans A Kretzschmar
Low values of 5-hydroxymethylcytosine (5hmC), the "sixth base," are associated with anaplasia in human brain tumors.
International journal of cancer. Journal international du cancer 2012;131(7):1577-90.
2012: Alexandra Frick; Daniel Grammel; Jochen Herms; Hans A Kretzschmar; Pierfrancesco Pagella; Aurelia Peraud; Julia Pöschl; Markus Priller; Stefan Rutkowski; Felix Schmidt; Jörg-Christian Tonn; André O von Bueren; Ulrich Schüller
Proper cerebellar development requires expression of β1-integrin in Bergmann glia, but not in granule neurons.
Glia 2012;60(5):820-32.
2012: Daniel Grammel; Marcel Kool; Hans A Kretzschmar; Stefan M Pfister; Torsten Pietsch; David H Rowitch; Stefan Rutkowski; André O von Bueren; Monika Warmuth-Metz; Ulrich Schüller
Sonic hedgehog-associated medulloblastoma arising from the cochlear nuclei of the brainstem.
Acta neuropathologica 2012;123(4):601-14.
2012: Gabi Schelzke; Hans A Kretzschmar; Inga Zerr
Clinical aspects of common genetic Creutzfeldt-Jakob disease.
European journal of epidemiology 2012;27(2):147-9.
2012: Christian Schön; Mathias W Seeliger; Sonja Steinbach; Thomas Arzberger; Steffen Burgold; Severin Filser; Michel Goedert; Nadine A Hoffmann; Hans A Kretzschmar; Simon M Ochs; Boris Schmidt; Jochen Herms
Long-term in vivo imaging of fibrillar tau in the retina of P301S transgenic mice.
PloS one 2012;7(12):e53547.
2012: Sarah Jesse; Hans A Kretzschmar; Hasan Kulaksiz; Stefan Lehnert; Martin Lenter; Manuela Neumann; Boris Ferger; Bastian Hengerer; Sanna-Kaisa Herukka; Olaf Jahn; Lucilla Parnetti; Hilkka Soininen; Petra Steinacker; Saskia Tawfik; Hayrettin Tumani; Christine A F Von Arnim; Jens Wiltfang; Markus Otto
Differential sialylation of serpin A1 in the early diagnosis of Parkinson's disease dementia.
PloS one 2012;7(11):e48783.
2012: Christian Schmidt; Jean-Philippe Brandel; Miguel Calero-Lara; Jesús de Pedro-Cuesta; Stephane Haïk; Jean-Jaques Hauw; Hans A Kretzschmar; Jean-Louis Laplanche; Pablo Martinez-Martin; Alberto Rábano; Sigrun Roeber; Katsuya Satoh; Inga Zerr
Rapidly progressive Alzheimer's disease: a multicenter update.
Journal of Alzheimer's disease : JAD 2012;30(4):751-6.
2011: L de Boni; Armin Giese; Sigrun Roeber; S Tierling; Jochen Walter; Hans A Kretzschmar
Next-generation sequencing reveals regional differences of the α-synuclein methylation state independent of Lewy body disease.
Neuromolecular medicine 2011;13(4):310-20.
2011: K L Roos; L A Gerdes; Hans A Kretzschmar; Tania Kümpfel; K Kurz; Joseph E Parisi; B M Keegan
An enhancing brainstem lesion in a patient with a history of worldwide travel.
Neurology 2011;77(19):1756-60.
2011: Sabina Eigenbrod; Armin Giese; Eva Grasbon-Frodl; Friedrich W Kreth; Anna Krieger; Sigrun Roeber; Niklas Thon; Jörg-Christian Tonn; Rupert Egensperger; Hans A Kretzschmar
α-Internexin in the diagnosis of oligodendroglial tumors and association with 1p/19q status.
Journal of neuropathology and experimental neurology 2011;70(11):970-8.
2011: Monika B Hartig; Katharina Heim; Maja Hempel; Arcangela Iuso; Sergiusz Jozwiak; Elzbieta Jurkiewicz; Thomas Klopstock; Tomasz Kmiec; Malgorzata Krajewska-Walasek; Hans A Kretzschmar; Thomas Meitinger; Wolfgang Mueller-Felber; Konrad Oexle; Sabrina Dusi; Matthias Elstner; Thomas Gasser; Tobias Haack; Sigrun Roeber; Gerd Schmitz; Tim M Strom; Victoria Tarabin; Valeria Tiranti; Claudia Trenkwalder; Juliane Winkelmann; Holger Prokisch
Absence of an orphan mitochondrial protein, c19orf12, causes a distinct clinical subtype of neurodegeneration with brain iron accumulation.
American journal of human genetics 2011;89(4):543-50.
2011: Markus Geissen; Armin Giese; Uwe Bertsch; Martin Eiden; Christine Fast; Thomas Hirschberger; Hans A Kretzschmar; Fabienne Leidel; Hermann M Schatzl; Paul Tavan; Martin H Groschup
From high-throughput cell culture screening to mouse model: identification of new inhibitor classes against prion disease.
ChemMedChem 2011;6(10):1928-37.
2011: Fabienne Leidel; Hermann M Schätzl; Paul Tavan; Thomas Hirschberger; Hans A Kretzschmar; Martin Eiden; Markus Geissen; Armin Giese; Martin H Groschup
Diphenylpyrazole-derived compounds increase survival time of mice after prion infection.
Antimicrobial agents and chemotherapy 2011;55(10):4774-81.
2011: Philipp Ottis; Svenja V Trossbach; Verian Bader; Hans A Kretzschmar; S Rutger Leliveld; Max Michel; Carsten Korth
Convergence of two independent mental disease genes on the protein level: recruitment of dysbindin to cell-invasive disrupted-in-schizophrenia 1 aggresomes.
Biological psychiatry 2011;70(7):604-10.
2011: Manuela Neumann; Rosa Rademakers; Sigrun Roeber; Osamu Yokota; David G Munoz; Lee Cyn Ang; Olaf Ansorge; Eva Bentmann; Juan Bilbao; Mariely DeJesus-Hernandez; Dorothee Dormann; Christian Haass; Ali Jawaid; Hans A Kretzschmar; Hirofumi Kusaka; Ian R A Mackenzie
FET proteins TAF15 and EWS are selective markers that distinguish FTLD with FUS pathology from amyotrophic lateral sclerosis with FUS mutations.
Brain : a journal of neurology 2011;134(Pt 9):2595-609.
2011: Markus Otto; M Schroeter; Adrian Danek; J Diehl-Schmid; hans förstl; J Kornhuber; Hans A Kretzschmar; B Landwehrmeyer; Albert C Ludolph; Manuela Neumann
[German consortium for frontotemporal lobar degeneration].
Der Nervenarzt 2011;82(8):1002-5.
2011: Andreas Lorenz; Catharina Prix; Ron Smits; Julia Ahlfeld; Markus Deutschmann; Riccardo Fodde; Arend Koch; Hans A Kretzschmar; Ulrich Schüller
Severe alterations of cerebellar cortical development after constitutive activation of Wnt signaling in granule neuron precursors.
Molecular and cellular biology 2011;31(16):3326-38.
2011: Benedikt Bader; Hans A Kretzschmar; Anja Mehle; Simona Nobile; Georg Nübling; Armin Giese
Single particle analysis of tau oligomer formation induced by metal ions and organic solvents.
Biochemical and biophysical research communications 2011;411(1):190-6.
2011: Ulrike K Resenberger; Anja Harmeier; Andreas C Woerner; Jessica L Goodman; Veronika Müller; Rajaraman Krishnan; R Martin Vabulas; Hans A Kretzschmar; Susan Lindquist; F Ulrich Hartl; Gerd Multhaup; Konstanze F Winklhofer; Jörg Tatzelt
The cellular prion protein mediates neurotoxic signalling of β-sheet-rich conformers independent of prion replication.
The EMBO journal 2011;30(10):2057-70.
2011: Brit Mollenhauer; Hermann Esselmann; Sigrun Roeber; Walter J Schulz-Schaeffer; Claudia Trenkwalder; Mirko Bibl; Petra Steinacker; Hans A Kretzschmar; Jens Wiltfang; Markus Otto
Different CSF β-amyloid processing in Alzheimer's and Creutzfeldt-Jakob disease.
Journal of neural transmission (Vienna, Austria : 1996) 2011;118(5):691-7.
2011: Giorgio Giaccone; Thomas Arzberger; Irina Alafuzoff; Safa Al-Sarraj; Herbert Budka; Charles Duyckaerts; Peter Falkai; Isidro Ferrer; James W Ironside; Gábor G Kovács; David Meyronet; Piero Parchi; Efstratios Patsouris; Tamas Revesz; Peter Riederer; Annemieke Rozemuller; Andrea Schmitt; Bengt Winblad; Hans A Kretzschmar
New lexicon and criteria for the diagnosis of Alzheimer's disease.
Lancet neurology 2011;10(4):298-9; author reply 300-1.
2011: Gabi Schelzke; Sabina Eigenbrod; Carlos Romero; Daniela Varges; Maren Breithaupt; Ana L Taratuto; Hans A Kretzschmar; Inga Zerr
Genetic prion disease with codon 196 PRNP mutation: clinical and pathological findings.
Neurobiology of aging 2011;32(4):756.e1-9.
2011: Andrea Schmitt; Fernando Leonardi-Essmann; Pascal F Durrenberger; Eleni Parlapani; Thomas Schneider-Axmann; Rainer Spanagel; Thomas Arzberger; Hans A Kretzschmar; Mario Herrera-Marschitz; Oliver Gruber; Richard Reynolds; Peter Falkai; Peter J Gebicke-Haerter
Regulation of immune-modulatory genes in left superior temporal cortex of schizophrenia patients: a genome-wide microarray study.
The world journal of biological psychiatry : the official journal of the World Federation of Societies of Biological Psychiatry 2011;12(3):201-15.
2011: Niklas Thon; Sabina Eigenbrod; Eva M Grasbon-Frodl; Juergen Lutz; Simone Kreth; Gabriele Popperl; Claus Belka; Hans A Kretzschmar; Joerg-Christian Tonn; Friedrich W Kreth
Predominant influence of MGMT methylation in non-resectable glioblastoma after radiotherapy plus temozolomide.
Journal of neurology, neurosurgery, and psychiatry 2011;82(4):441-6.
2011: Sabina Eigenbrod; Petra Frick; Armin Giese; Gabi Schelzke; Inga Zerr; Hans A Kretzschmar
Comprehensive neuropathologic analysis of genetic prion disease associated with the E196K mutation in PRNP reveals phenotypic heterogeneity.
Journal of neuropathology and experimental neurology 2011;70(3):192-200.
2011: M Kunz; N Thon; S Eigenbrod; C Hartmann; Rupert Egensperger; Jochen Herms; J Geisler; Christian la Fougere; J Lutz; J Linn; S Kreth; A von Deimling; Jörg-Christian Tonn; Hans A Kretzschmar; Gabriele Pöpperl; Friedrich W Kreth
Hot spots in dynamic (18)FET-PET delineate malignant tumor parts within suspected WHO grade II gliomas.
Neuro-oncology 2011;13(3):307-16.
2011: Steffen Burgold; Tobias Bittner; Mario M Dorostkar; Daniel Kieser; Martin Fuhrmann; Gerda Mitteregger; Hans A Kretzschmar; Boris Schmidt; Jochen Herms
In vivo multiphoton imaging reveals gradual growth of newborn amyloid plaques over weeks.
Acta neuropathologica 2011;121(3):327-35.
2011: Ian R A Mackenzie; David G Munoz; Hirofumi Kusaka; Osamu Yokota; Kenji Ishihara; Sigrun Roeber; Hans A Kretzschmar; Nigel J Cairns; Manuela Neumann
Distinct pathological subtypes of FTLD-FUS.
Acta neuropathologica 2011;121(2):207-18.
2011: Michael A Tranulis; Thierry Baron; Sylvie Benestad; Hans A Kretzschmar
Atypical prion diseases in humans and animals.
Topics in current chemistry 2011;305():23-50.
2011: Simone Kreth; Niklas Thon; Sabina Eigenbrod; Juergen Lutz; Carola Ledderose; Rupert Egensperger; Joerg C Tonn; Hans A Kretzschmar; Ludwig C Hinske; Friedrich W Kreth
O-methylguanine-DNA methyltransferase (MGMT) mRNA expression predicts outcome in malignant glioma independent of MGMT promoter methylation.
PloS one 2011;6(2):e17156.
2011: Brit Mollenhauer; Hermann Esselmann; Claudia Trenkwalder; Walter Schulz-Schaeffer; Hans A Kretzschmar; Markus Otto; Jens Wiltfang; Mirko Bibl
CSF amyloid-β peptides in neuropathologically diagnosed dementia with Lewy bodies and Alzheimer's disease.
Journal of Alzheimer's disease : JAD 2011;24(2):383-91.
2011: Piero Parchi; Rosaria Strammiello; Armin Giese; Hans A Kretzschmar
Phenotypic variability of sporadic human prion disease and its molecular basis: past, present, and future.
Acta neuropathologica 2011;121(1):91-112.
2011: Sabina Capellari; Rosaria Strammiello; Daniela Saverioni; Hans A Kretzschmar; Piero Parchi
Genetic Creutzfeldt-Jakob disease and fatal familial insomnia: insights into phenotypic variability and disease pathogenesis.
Acta neuropathologica 2011;121(1):21-37.
2010: Piero Parchi; Maura Cescatti; Silvio Notari; Walter J Schulz-Schaeffer; Sabina Capellari; Armin Giese; Wen-Quan Zou; Hans A Kretzschmar; Bernardino Ghetti; Paul Brown
Agent strain variation in human prion disease: insights from a molecular and pathological review of the National Institutes of Health series of experimentally transmitted disease.
Brain : a journal of neurology 2010;133(10):3030-42.
2010: A Schmitt; Ingo M Westner; L Reznicek; W Michels; Gerda Mitteregger; Hans A Kretzschmar
Automated decontamination of surface-adherent prions.
The Journal of hospital infection 2010;76(1):74-9.
2010: Petra Sostak; Claudio S Padovan; S Eigenbrod; Sigrun Roeber; Stephan Segerer; C Schankin; Sabine I Siegert; Tobias Saam; Diethilde Theil; Hans-Jochem Kolb; Hans A Kretzschmar; Andreas Straube
Cerebral angiitis in four patients with chronic GVHD.
Bone marrow transplantation 2010;45(7):1181-8.
2010: Simone Kreth; Jens Heyn; Stefan Grau; Hans A Kretzschmar; Rupert Egensperger; Friedrich W Kreth
Identification of valid endogenous control genes for determining gene expression in human glioma.
Neuro-oncology 2010;12(6):570-9.
2010: Thomas Pfefferkorn; U Schüller; C Cyran; Katharina Hüfner; Gunther Fesl; Klaus Seelos; Martin Dichgans; Hans-Walter Pfister; K Nikolaou; Hans A Kretzschmar; Tobias Saam
Giant cell arteritis of the Basal cerebral arteries: correlation of MRI, dsa, and histopathology.
Neurology 2010;74(20):1651-3.
2010: Johannes Levin; Stefanie Bulst; Christian Thirion; Felix Schmidt; Kai Bötzel; Sabine Krause; Cordula Pertl; Hans A Kretzschmar; Maggie C Walter; Armin Giese; Hanns Lochmüller
Divergent molecular effects of desmin mutations on protein assembly in myofibrillar myopathy.
Journal of neuropathology and experimental neurology 2010;69(4):415-24.
2010: Martin Fuhrmann; Tobias Bittner; Christian K E Jung; Steffen Burgold; Richard M Page; Gerda Mitteregger; Christian Haass; Frank M LaFerla; Hans A Kretzschmar; Jochen Herms
Microglial Cx3cr1 knockout prevents neuron loss in a mouse model of Alzheimer's disease.
Nature neuroscience 2010;13(4):411-3.
2010: Jan Rémi; Thomas Pfefferkorn; Fatima B König; Hans Lassmann; Wolfgang Brück; Markus Holtmannspötter; Andreas Straube; Hans A Kretzschmar; Ulrich Schüller
A 76-year-old woman with paraplegia.
Brain pathology (Zurich, Switzerland) 2010;20(2):507-10.
2010: Vivianna M Van Deerlin; Patrick M A Sleiman; Maria Martinez-Lage; Alice Chen-Plotkin; Li-San Wang; Neill R Graff-Radford; dennis dickson; Rosa Rademakers; Bradley F Boeve; Murray Grossman; Steven E Arnold; D M A Mann; Stuart M Pickering-Brown; Harro Seelaar; Peter Heutink; John C van Swieten; Jill R Murrell; Bernardino Ghetti; Salvatore Spina; Jordan Grafman; John R Hodges; Maria Grazia Spillantini; Sid Gilman; Andrew P Lieberman; Jeffrey A Kaye; Randall L Woltjer; Eileen H Bigio; Marsel Mesulam; Safa Al-Sarraj; Claire Troakes; Roger N Rosenberg; Charles L White; Isidro Ferrer; Albert Lladó; Manuela Neumann; Hans A Kretzschmar; Christine Marie Hulette; Kathleen A Welsh-Bohmer; Bruce L Miller; Ainhoa Alzualde; Adolfo Lopez de Munain; Ann C McKee; Marla Gearing; Allan Levey; James J Lah; John Hardy; Jonathan D Rohrer; Tammaryn Lashley; Ian R A Mackenzie; Howard H Feldman; Ronald L Hamilton; Steven T DeKosky; Julie van der Zee; Samir Kumar-Singh; Christine Van Broeckhoven; Richard Mayeux; Jean Paul G Vonsattel; Juan C Troncoso; Jillian J Kril; John B J Kwok; Glenda M Halliday; Thomas D Bird; Paul Geoffrey Ince; Pamela J Shaw; Nigel J Cairns; John C Morris; Catriona Ann McLean; Charles DeCarli; William G Ellis; Stefanie H Freeman; Matthew P Frosch; John H Growdon; Daniel P Perl; Mary Sano; David A Bennett; Julie A Schneider; Thomas Beach; Eric Reiman; Bryan Woodruff; Jeffrey L Cummings; Harry V Vinters; Carol A Miller; Helena C Chui; Irina Alafuzoff; Päivi Hartikainen; Danielle Seilhean; Douglas Galasko; Eliezer Masliah; Carl W Cotman; M Teresa Tuñón; M Cristina Caballero Martínez; David G Munoz; Steven L Carroll; Daniel Marson; Peter F Riederer; Nenad Bogdanovic; Gerard D Schellenberg; Hakon Hakonarson; John Q Trojanowski; Virginia M-Y Lee
Common variants at 7p21 are associated with frontotemporal lobar degeneration with TDP-43 inclusions.
Nature genetics 2010;42(3):234-9.
2010: Yue Tang; Wei Xiang; Linda Terry; Hans A Kretzschmar; Otto Windl
Transcriptional analysis implicates endoplasmic reticulum stress in bovine spongiform encephalopathy.
PloS one 2010;5(12):e14207.
2010: Tobias Bittner; Martin Fuhrmann; Steffen Burgold; Simon M Ochs; Nadine Hoffmann; Gerda Mitteregger; Hans A Kretzschmar; Frank M LaFerla; Jochen Herms
Multiple events lead to dendritic spine loss in triple transgenic Alzheimer's disease mice.
PloS one 2010;5(11):e15477.
2010: Petra Steinacker; Hans Klafki; Stefan Lehnert; Sarah Jesse; Christine A F V Arnim; Hayrettin Tumani; Alice Pabst; Hans A Kretzschmar; Jens Wiltfang; Markus Otto
ERK2 is increased in cerebrospinal fluid of Creutzfeldt-Jakob disease patients.
Journal of Alzheimer's disease : JAD 2010;22(1):119-28.
2010: Christian Schmidt; Katharina Redyk; Bettina Meissner; Lennart Krack; Nicolas Von Ahsen; Sigrun Roeber; Hans A Kretzschmar; Inga Zerr
Clinical features of rapidly progressive Alzheimer's disease.
Dementia and geriatric cognitive disorders 2010;29(4):371-8.
2010: Alexander Baraniskin; Andreas Jähnert; Guido Ahle; Anja Theile; Hans A Kretzschmar; Wolff Schmiegel; Roland Schroers
Intravascular large B-cell lymphoma presenting as dementia and hemolytic anemia.
Onkologie 2010;33(4):174-7.
2010: Pascal F Durrenberger; Shama Fernando; Samira N Kashefi; Isidro Ferrer; JEAN-JACQUES HAUW; Danielle Seilhean; Colin Smith; Robert Walker; Safa Al-Sarraj; Claire Troakes; Miklós Palkovits; Magdalena Kasztner; Inge Huitinga; Thomas Arzberger; David T Dexter; Hans A Kretzschmar; Richard Reynolds
Effects of antemortem and postmortem variables on human brain mRNA quality: a BrainNet Europe study.
Journal of neuropathology and experimental neurology 2010;69(1):70-81.
2010: Andreas S Hillmer; Preeti Putcha; Johannes Levin; Tobias Högen; Bradley T Hyman; Hans A Kretzschmar; Pamela J McLean; Armin Giese
Converse modulation of toxic alpha-synuclein oligomers in living cells by N'-benzylidene-benzohydrazide derivates and ferric iron.
Biochemical and biophysical research communications 2010;391(1):461-6.
2010: Petra Steinacker; Wolfgang Rist; Magdalena Swiatek-de Lange; Stefan Lehnert; Sarah Jesse; Alice Pabst; Hayrettin Tumani; Christine A F Von Arnim; Eva Mitrova; Hans A Kretzschmar; Martin Lenter; Jens Wiltfang; Markus Otto
Ubiquitin as potential cerebrospinal fluid marker of Creutzfeldt-Jakob disease.
Proteomics 2010;10(1):81-9.
2009: Oliver Schnell; Bjarne Krebs; Janette Carlsen; Isabelle Miederer; Claudia Goetz; Roland Goldbrunner; Hans-Jürgen Wester; Roland Haubner; Gabriele Pöpperl; Markus Holtmannspötter; Hans A Kretzschmar; Horst Kessler; Jörg-Christian Tonn; Markus Schwaiger; Ambros J Beer
Imaging of integrin alpha(v)beta(3) expression in patients with malignant glioma by [18F] Galacto-RGD positron emission tomography.
Neuro-oncology 2009;11(6):861-70.
2009: Niklas Thon; Sabina Eigenbrod; Eva Grasbon-Frodl; Michael Ruiter; Jan H Mehrkens; Simone Kreth; Jörg-Christian Tonn; Hans A Kretzschmar; Friedrich W Kreth
Novel molecular stereotactic biopsy procedures reveal intratumoral homogeneity of loss of heterozygosity of 1p/19q and TP53 mutations in World Health Organization grade II gliomas.
Journal of neuropathology and experimental neurology 2009;68(11):1219-28.
2009: Piero Parchi; Rosaria Strammiello; Silvio Notari; Armin Giese; Jan P M Langeveld; Anna Ladogana; Inga Zerr; Federico Roncaroli; Patrick cras; Bernardino Ghetti; Maurizio Pocchiari; Hans A Kretzschmar; Sabina Capellari
Incidence and spectrum of sporadic Creutzfeldt-Jakob disease variants with mixed phenotype and co-occurrence of PrPSc types: an updated classification.
Acta neuropathologica 2009;118(5):659-71.
2009: Manuela Neumann; Rosa Rademakers; Sigrun Roeber; Matt Baker; Hans A Kretzschmar; Ian R A Mackenzie
A new subtype of frontotemporal lobar degeneration with FUS pathology.
Brain : a journal of neurology 2009;132(Pt 11):2922-31.
2009: Manuela Neumann; Sigrun Roeber; Hans A Kretzschmar; Rosa Rademakers; Matt Baker; Ian R A Mackenzie
Abundant FUS-immunoreactive pathology in neuronal intermediate filament inclusion disease.
Acta neuropathologica 2009;118(5):605-16.
2009: Kristina Endres; Gerda Mitteregger; Elzbieta Kojro; Hans A Kretzschmar; Falk Fahrenholz
Influence of ADAM10 on prion protein processing and scrapie infectiosity in vivo.
Neurobiology of disease 2009;36(2):233-41.
2009: K Gmitterová; U Heinemann; M Bodemer; A Krasnianski; B Meissner; Hans A Kretzschmar; I Zerr
14-3-3 CSF levels in sporadic Creutzfeldt-Jakob disease differ across molecular subtypes.
Neurobiology of aging 2009;30(11):1842-50.
2009: Gerda Mitteregger; Stefan Korte; Mehdi Shakarami; Jochen Herms; Hans A Kretzschmar
Role of copper and manganese in prion disease progression.
Brain research 2009;1292():155-64.
2009: Yue Tang; Wei Xiang; Steve A C Hawkins; Hans A Kretzschmar; Otto Windl
Transcriptional changes in the brains of cattle orally infected with the bovine spongiform encephalopathy agent precede detection of infectivity.
Journal of virology 2009;83(18):9464-73.
2009: Frank Winkler; Yvonne Kienast; Martin Fuhrmann; Louisa Von Baumgarten; Steffen Burgold; Gerda Mitteregger; Hans A Kretzschmar; Jochen Herms
Imaging glioma cell invasion in vivo reveals mechanisms of dissemination and peritumoral angiogenesis.
Glia 2009;57(12):1306-15.
2009: Tobias Bittner; Martin Fuhrmann; Steffen Burgold; Christian K E Jung; Christiane Volbracht; Harald Steiner; Gerda Mitteregger; Hans A Kretzschmar; Christian Haass; Jochen Herms
Gamma-secretase inhibition reduces spine density in vivo via an amyloid precursor protein-dependent pathway.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2009;29(33):10405-9.
2009: Christina Priller; Gerda Mitteregger; Sandra Paluch; Neville Vassallo; Matthias Staufenbiel; Hans A Kretzschmar; Mathias Jucker; Jochen Herms
Excitatory synaptic transmission is depressed in cultured hippocampal neurons of APP/PS1 mice.
Neurobiology of aging 2009;30(8):1227-37.
2009: Piero Parchi; Silvio Notari; Petra Frick; Heinz Schimmel; Herbert Budka; Isidre Ferrer; Stéphane Haik; JEAN-JACQUES HAUW; Mark W Head; James W Ironside; Lucia Limido; Agustin Rodriguez; Thomas Ströbel; Fabrizio Tagliavini; Hans A Kretzschmar
Inter-laboratory assessment of PrPSc typing in creutzfeldt-jakob disease: a Western blot study within the NeuroPrion Consortium.
Brain pathology (Zurich, Switzerland) 2009;19(3):384-91.
2009: Irina Alafuzoff; Paul Geoffrey Ince; Thomas Arzberger; Safa Al-Sarraj; Jeanne Bell; Istvan Bodi; Nenad Bogdanovic; Orso Bugiani; Isidro Ferrer; Ellen Gelpi; Stephen M Gentleman; Giorgio Giaccone; James W Ironside; Nikolaos Kavantzas; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; David Meyronet; Camelia Monoranu; Piero Parchi; Laura Parkkinen; Efstratios Patsouris; Wolfgang Roggendorf; Annemieke Rozemuller; Christine Stadelmann-Nessler; Nathalie Streichenberger; Dietmar R Thal; Hans A Kretzschmar
Staging/typing of Lewy body related alpha-synuclein pathology: a study of the BrainNet Europe Consortium.
Acta neuropathologica 2009;117(6):635-52.
2009: Heike Pflanz; Karen Vana; Gerda Mitteregger; Ingrid Renner-Müller; Claudia Pace; Helmut Küchenhoff; Hans A Kretzschmar; Eckhard Wolf; Stefan Weiss
Scrapie-infected transgenic mice expressing a laminin receptor decoy mutant reveal a prolonged incubation time associated with low levels of PrPres.
Journal of molecular biology 2009;388(4):721-9.
2009: Christina Wolschner; Armin Giese; Hans A Kretzschmar; Robert Huber; Luis Moroder; Nediljko Budisa
Design of anti- and pro-aggregation variants to assess the effects of methionine oxidation in human prion protein.
Proceedings of the National Academy of Sciences of the United States of America 2009;106(19):7756-61.
2009: Klaus Jahn; Viktor Arbusow; Vera C Zingler; Michael Strupp; Hans A Kretzschmar; Thomas Brandt
Bilateral vestibular failure as an early sign in Creutzfeldt-Jakob disease.
Annals of the New York Academy of Sciences 2009;1164():390-3.
2009: U Wüllner; I Schmitt; M Kammal; Hans A Kretzschmar; M Neumann
Definite multiple system atrophy in a German family.
Journal of neurology, neurosurgery, and psychiatry 2009;80(4):449-50.
2009: Anna Krasnianski; Nicolas Von Ahsen; Uta Heinemann; Bettina Meissner; Walter Schulz-Schaeffer; Hans A Kretzschmar; Victor W Armstrong; Inga Zerr
Increased frequency of positive family history of dementia in sporadic CJD.
Neurobiology of aging 2009;30(4):615-21.
2009: A C Ludolph; J Kassubek; B G Landwehrmeyer; Eva-Maria Mandelkow; Eckhard Mandelkow; David J Burn; D Caparros-Lefebvre; Kirk A Frey; J G de Yebenes; T Gasser; Peter Heutink; G Höglinger; Z Jamrozik; Kurt A Jellinger; A Kazantsev; Hans A Kretzschmar; Anthony E Lang; I Litvan; J J Lucas; Patrick L McGeer; S Melquist; Wolfgang H Oertel; M Otto; D Paviour; T Reum; A Saint-Raymond; J C Steele; M Tolnay; H Tumani; J C van Swieten; M T Vanier; J-P Vonsattel; S Wagner; Zbigniew K Wszolek
Tauopathies with parkinsonism: clinical spectrum, neuropathologic basis, biological markers, and treatment options.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2009;16(3):297-309.
2009: Irina Alafuzoff; Dietmar R Thal; Thomas Arzberger; Nenad Bogdanovic; Safa Al-Sarraj; Istvan Bodi; Susan Boluda; Orso Bugiani; Charles Duyckaerts; Ellen Gelpi; Stephen M Gentleman; Giorgio Giaccone; Manuel Graeber; Tibor Hortobagyi; Romana Höftberger; Paul Ince; James W Ironside; Nikolaos Kavantzas; Andrew King; Penelope Korkolopoulou; Gábor G Kovács; David Meyronet; Camelia Monoranu; Tatjana Nilsson; Piero Parchi; Efstratios Patsouris; Maria Pikkarainen; Tamas Revesz; Annemieke Rozemuller; Danielle Seilhean; Walter Schulz-Schaeffer; Nathalie Streichenberger; Stephen B Wharton; Hans A Kretzschmar
Assessment of beta-amyloid deposits in human brain: a study of the BrainNet Europe Consortium.
Acta neuropathologica 2009;117(3):309-20.
2009: B Meissner; Kai Kallenberg; P Sanchez-Juan; S Ramljak; Anna Krasnianski; Uta Heinemann; S Eigenbrod; E Gelpi; B Barsic; Hans A Kretzschmar; Walter Schulz-Schaeffer; Michael Knauth; Inga Zerr
MRI and clinical syndrome in dura mater-related Creutzfeldt-Jakob disease.
Journal of neurology 2009;256(3):355-63.
2009: Manuela Neumann; Linda K Kwong; Edward B Lee; Elisabeth Kremmer; Andrew Flatley; Yan Xu; Mark S Forman; Dirk Troost; Hans A Kretzschmar; John Q Trojanowski; Virginia M-Y Lee
Phosphorylation of S409/410 of TDP-43 is a consistent feature in all sporadic and familial forms of TDP-43 proteinopathies.
Acta neuropathologica 2009;117(2):137-49.
2009: Sarah Jesse; Petra Steinacker; Lukas Cepek; Christine A F Von Arnim; Hayrettin Tumani; Stefan Lehnert; Hans A Kretzschmar; Michael Baier; Markus Otto
Glial fibrillary acidic protein and protein S-100B: different concentration pattern of glial proteins in cerebrospinal fluid of patients with Alzheimer's disease and Creutzfeldt-Jakob disease.
Journal of Alzheimer's disease : JAD 2009;17(3):541-51.
2009: Heike Pflanz; Karen Vana; Gerda Mitteregger; Claudia Pace; Diana Messow; Cilli Sedlaczek; Daphne Nikles; Hans A Kretzschmar; Stefan F T Weiss
Microinjection of lentiviral vectors expressing small interfering RNAs directed against laminin receptor precursor mRNA prolongs the pre-clinical phase in scrapie-infected mice.
The Journal of general virology 2009;90(Pt 1):269-74.
2009: Hans A Kretzschmar; Thomas Illig
Are further genetic factors associated with the risk of developing variant Creutzfeldt-Jakob disease?
Lancet neurology 2009;8(1):25-6.
2009: Hans A Kretzschmar
Brain banking: opportunities, challenges and meaning for the future.
Nature reviews. Neuroscience 2009;10(1):70-8.
2009: Johannes Levin; Armin Giese; Kai Boetzel; Lars Israel; Tobias Högen; Georg Nübling; Hans A Kretzschmar; Stefan Lorenzl
Increased alpha-synuclein aggregation following limited cleavage by certain matrix metalloproteinases.
Experimental neurology 2009;215(1):201-8.
2008: Silvio Notari; Rosaria Strammiello; Sabina Capellari; Armin Giese; Maura Cescatti; Jacques Grassi; Bernardino Ghetti; Jan P M Langeveld; Wen-Quan Zou; Pierluigi Gambetti; Hans A Kretzschmar; Piero Parchi
Characterization of truncated forms of abnormal prion protein in Creutzfeldt-Jakob disease.
The Journal of biological chemistry 2008;283(45):30557-65.
2008: Petra Steinacker; Corinna Hendrich; Anne-Dorte Sperfeld; Sarah Jesse; Christine A F Von Arnim; Stefan Lehnert; Alice Pabst; Ingo Uttner; Hayrettin Tumani; Virginia M-Y Lee; John Q Trojanowski; Hans A Kretzschmar; Albert C Ludolph; Manuela Neumann; Markus Otto
TDP-43 in cerebrospinal fluid of patients with frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Archives of neurology 2008;65(11):1481-7.
2008: Manuela Neumann; Hans A Kretzschmar
[Molecular neuropathology of Non-Alzheimer dementia].
Der Pathologe 2008;29(6):434-41.
2008: Uta Heinemann; Anna Krasnianski; Bettina Meissner; Kai Kallenberg; Hans A Kretzschmar; Walter Schulz-Schaeffer; Inga Zerr
Brain biopsy in patients with suspected Creutzfeldt-Jakob disease.
Journal of neurosurgery 2008;109(4):735-41.
2008: Peter Brechlin; Olaf Jahn; Petra Steinacker; Lukas Cepek; Hartmut Kratzin; Stefan Lehnert; Sarah Jesse; Brit Mollenhauer; Hans A Kretzschmar; Jens Wiltfang; Markus Otto
Cerebrospinal fluid-optimized two-dimensional difference gel electrophoresis (2-D DIGE) facilitates the differential diagnosis of Creutzfeldt-Jakob disease.
Proteomics 2008;8(20):4357-66.
2008: Brit Mollenhauer; Valerie Cullen; Ilana Kahn; Bryan Krastins; Tiago Outeiro; Imelda Pepivani; Juliana Ng; Walter Schulz-Schaeffer; Hans A Kretzschmar; Pamela J McLean; Claudia Trenkwalder; David A Sarracino; Jean-Paul Vonsattel; Joseph J Locascio; Omar M A El-Agnaf; Michael G Schlossmacher
Direct quantification of CSF alpha-synuclein by ELISA and first cross-sectional study in patients with neurodegeneration.
Experimental neurology 2008;213(2):315-25.
2008: Irina Alafuzoff; Thomas Arzberger; Safa Al-Sarraj; Istvan Bodi; Nenad Bogdanovic; Heiko Braak; Orso Bugiani; Kelly Del Tredici; Isidro Ferrer; Ellen Gelpi; Giorgio Giaccone; Manuel B Graeber; Paul Ince; Wouter Kamphorst; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; Sergey Larionov; David Meyronet; Camelia Monoranu; Piero Parchi; Efstratios Patsouris; Wolfgang Roggendorf; Danielle Seilhean; Fabrizio Tagliavini; Christine Stadelmann; Nathalie Streichenberger; Dietmar R Thal; Stephen B Wharton; Hans A Kretzschmar
Staging of neurofibrillary pathology in Alzheimer's disease: a study of the BrainNet Europe Consortium.
Brain pathology (Zurich, Switzerland) 2008;18(4):484-96.
2008: Peter Kühnlein; Anne-Dorte Sperfeld; Ben Vanmassenhove; Vivianna Van Deerlin; Virginia M-Y Lee; John Q Trojanowski; Hans A Kretzschmar; Albert C Ludolph; Manuela Neumann
Two German kindreds with familial amyotrophic lateral sclerosis due to TARDBP mutations.
Archives of neurology 2008;65(9):1185-9.
2008: Anna Krasnianski; Kai Kallenberg; D A Collie; Bettina Meissner; W J Schulz-Schaeffer; Uta Heinemann; Daniela Varges; D M Summers; Hans A Kretzschmar; T Talbot; R G Will; Inga Zerr
MRI in the classical MM1 and the atypical MV2 subtypes of sporadic CJD: an inter-observer agreement study.
European journal of neurology : the official journal of the European Federation of Neurological Societies 2008;15(8):762-71.
2008: Chantal Zuber; Gerda Mitteregger; Natascha Schuhmann; Clémence Rey; Stefan Knackmuss; Wolfgang Rupprecht; Uwe Reusch; Claudia Pace; Melvyn Little; Hans A Kretzschmar; Michael Hallek; Hildegard Büning; Stefan Weiss
Delivery of single-chain antibodies (scFvs) directed against the 37/67 kDa laminin receptor into mice via recombinant adeno-associated viral vectors for prion disease gene therapy.
The Journal of general virology 2008;89(Pt 8):2055-61.
2008: Sigrun Roeber; Ian R A Mackenzie; Hans A Kretzschmar; Manuela Neumann
TDP-43-negative FTLD-U is a significant new clinico-pathological subtype of FTLD.
Acta neuropathologica 2008;116(2):147-57.
2008: Rüdiger Schmalzbauer; Sabina Eigenbrod; Supandi Winoto-Morbach; Wei Xiang; Stefan Schütze; Uwe Bertsch; Hans A Kretzschmar
Evidence for an association of prion protein and sphingolipid-mediated signaling.
Journal of neurochemistry 2008;106(3):1459-70.
2008: Anna C Crecelius; Derrick Helmstetter; Julia Strangmann; Gerda Mitteregger; Thomas Fröhlich; Georg J Arnold; Hans A Kretzschmar
The brain proteome profile is highly conserved between Prnp-/- and Prnp+/+ mice.
Neuroreport 2008;19(10):1027-31.
2008: Andreas Heiseke; Susanne Schöbel; Stefan F Lichtenthaler; Ina Vorberg; Martin H Groschup; Hans A Kretzschmar; Hermann M Schätzl; Max Nunziante
The novel sorting nexin SNX33 interferes with cellular PrP formation by modulation of PrP shedding.
Traffic (Copenhagen, Denmark) 2008;9(7):1116-29.
2008: Oliver Schnell; Bjarne Krebs; Erika Wagner; Alexander Romagna; Ambros J Beer; Stefan J Grau; Niklas Thon; Claudia Goetz; Hans A Kretzschmar; Jörg-Christian Tonn; Roland H Goldbrunner
Expression of integrin alphavbeta3 in gliomas correlates with tumor grade and is not restricted to tumor vasculature.
Brain pathology (Zurich, Switzerland) 2008;18(3):378-86.
2008: Kunihiro Uryu; Hanae Nakashima-Yasuda; Mark S Forman; Linda K Kwong; Christopher M Clark; Murray Grossman; Bruce L Miller; Hans A Kretzschmar; Virginia M-Y Lee; John Q Trojanowski; Manuela Neumann
Concomitant TAR-DNA-binding protein 43 pathology is present in Alzheimer disease and corticobasal degeneration but not in other tauopathies.
Journal of neuropathology and experimental neurology 2008;67(6):555-64.
2008: Petra Frick; Lukas Reznicek; Gerda Mitteregger; Hans A Kretzschmar; Armin Giese
Differential effects of prion particle size on infectivity in vivo and in vitro.
Biochemical and biophysical research communications 2008;369(3):924-8.
2008: Uta Heinemann; Anna Krasnianski; Bettina Meissner; Eva M Grasbon-Frodl; Hans A Kretzschmar; Inga Zerr
Novel PRNP mutation in a patient with a slow progressive dementia syndrome.
Medical science monitor : international medical journal of experimental and clinical research 2008;14(5):CS41-43.
2008: Jeanne E Bell; Irina Alafuzoff; Safa Al-Sarraj; Thomas Arzberger; Nenad Bogdanovic; Herbert Budka; David T Dexter; Peter Falkai; Isidro Ferrer; Ellen Gelpi; Stephen M Gentleman; Giorgio Giaccone; Inge Huitinga; James W Ironside; Natasja Klioueva; Gabor Geza Kovacs; David Meyronet; Miklós Palkovits; Piero Parchi; Efstatios Patsouris; Richard Reynolds; Peter Riederer; Wolfgang Roggendorf; Danielle Seilhean; Andrea Schmitt; Peer Schmitz; Nathalie Streichenberger; Ameli Schwalber; Hans A Kretzschmar
Management of a twenty-first century brain bank: experience in the BrainNet Europe consortium.
Acta neuropathologica 2008;115(5):497-507.
2008: Anna Krasnianski; Mario Bartl; Pascual J Sanchez Juan; Uta Heinemann; Bettina Meissner; Daniela Varges; Ulf Schulze-Sturm; Hans A Kretzschmar; Walter Schulz-Schaeffer; Inga Zerr
Fatal familial insomnia: Clinical features and early identification.
Annals of neurology 2008;63(5):658-61.
2008: Irina Alafuzoff; Maria Pikkarainen; Thomas Arzberger; Dietmar R Thal; Safa Al-Sarraj; Jeanne Bell; Istvan Bodi; Herbert Budka; Estibaliz Capetillo-Zarate; Isidro Ferrer; Ellen Gelpi; Stephen M Gentleman; Giorgio Giaccone; Nikolaos Kavantzas; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; David Meyronet; Camelia Monoranu; Piero Parchi; Efstratios Patsouris; Wolfgang Roggendorf; Christine Stadelmann; Nathalie Streichenberger; Fabricio Tagliavini; Hans A Kretzschmar
Inter-laboratory comparison of neuropathological assessments of beta-amyloid protein: a study of the BrainNet Europe consortium.
Acta neuropathologica 2008;115(5):533-46.
2008: Marcus Kostka; Tobias Högen; Karin M Danzer; Johannes Levin; Matthias Habeck; Andreas Wirth; Richard Wagner; Charles G Glabe; Sabine Finger; Udo Heinzelmann; Patrick Garidel; WENZHEN DUAN; Christopher A Ross; Hans A Kretzschmar; Armin Giese
Single particle characterization of iron-induced pore-forming alpha-synuclein oligomers.
The Journal of biological chemistry 2008;283(16):10992-1003.
2008: Anna Crecelius; Andrea Götz; Thomas Arzberger; Thomas Fröhlich; Georg J Arnold; Isidro Ferrer; Hans A Kretzschmar
Assessing quantitative post-mortem changes in the gray matter of the human frontal cortex proteome by 2-D DIGE.
Proteomics 2008;8(6):1276-91.
2008: Ulrich Schüller; Michael Ruiter; Jochen Herms; Hans A Kretzschmar; Eva Grasbon-Frodl
Absence of mutations in the AKT1 oncogene in glioblastomas and medulloblastomas.
Acta neuropathologica 2008;115(3):367-8.
2008: Irina Alafuzoff; Laura Parkkinen; Safa Al-Sarraj; Thomas Arzberger; Jeanne Bell; Istvan Bodi; Nenad Bogdanovic; Herbert Budka; Isidro Ferrer; Ellen Gelpi; Stephen M Gentleman; Giorgio Giaccone; Wouter Kamphorst; Andrew King; Penelope Korkolopoulou; Gabor Geza Kovacs; Sergey Larionov; David Meyronet; Camelia Monoranu; Jodie Morris; Piero Parchi; Efstratios Patsouris; Wolfgang Roggendorf; Danielle Seilhean; Nathalie Streichenberger; Dietmar R Thal; Hans A Kretzschmar
Assessment of alpha-synuclein pathology: a study of the BrainNet Europe Consortium.
Journal of neuropathology and experimental neurology 2008;67(2):125-43.
2008: Gabor Geza Kovacs; Irina Alafuzoff; Safa Al-Sarraj; Thomas Arzberger; Nenad Bogdanovic; Sabina Capellari; Isidro Ferrer; Ellen Gelpi; Viktor Kövari; Hans A Kretzschmar; Zoltan Nagy; Piero Parchi; Danielle Seilhean; Hilkka Soininen; Claire Troakes; Herbert Budka
Mixed brain pathologies in dementia: the BrainNet Europe consortium experience.
Dementia and geriatric cognitive disorders 2008;26(4):343-50.
2008: Michel Mittelbronn; David Capper; Benedikt Bader; Jens Schittenhelm; Johannes Haybaeck; Petra Frick; Richard Meyermann; Hans A Kretzschmar; Horst Wietholter
Severe hypoxia and multiple infarctions resembling Creutzfeldt-Jakob disease.
Folia neuropathologica / Association of Polish Neuropathologists and Medical Research Centre, Polish Academy of Sciences 2008;46(2):149-53.
2008: Sigrun Roeber; Eva Grasbon-Frodl; Otto Windl; Bjarne Krebs; Wei Xiang; Caren Vollmert; Thomas Illig; Andreas Schröter; Thomas Arzberger; Petra Frick; Inga Zerr; Hans A Kretzschmar
Evidence for a pathogenic role of different mutations at codon 188 of PRNP.
PloS one 2008;3(5):e2147.
2008: M Friedrich; R Körte; C Portero; T Arzberger; Hans A Kretzschmar; I Zerr; W Nacimiento
[Fatal familial insomnia--a rare differential diagnosis in dementia].
Fortschritte der Neurologie-Psychiatrie 2008;76(1):36-40.
2008: Anna Krasnianski; Nicolas Von Ahsen; Uta Heinemann; Bettina Meissner; Hans A Kretzschmar; Victor W Armstrong; Inga Zerr
ApoE distribution and family history in genetic prion diseases in Germany.
Journal of molecular neuroscience : MN 2008;34(1):45-50.
2008: Chantal Zuber; Stefan Knackmuss; Clémence Rey; Uwe Reusch; Peter Röttgen; Thomas Fröhlich; Georg J Arnold; Claudia Pace; Gerda Mitteregger; Hans A Kretzschmar; Melvyn Little; Stefan Weiss
Single chain Fv antibodies directed against the 37 kDa/67 kDa laminin receptor as therapeutic tools in prion diseases.
Molecular immunology 2008;45(1):144-51.
2007: Domenico Paludi; Stefano Thellung; Katia Chiovitti; Alessandro Corsaro; Valentina Villa; Claudio Russo; ADRIANA IANIERI; Uwe Bertsch; Hans A Kretzschmar; Antonio Aceto; Tullio Florio
Different structural stability and toxicity of PrP(ARR) and PrP(ARQ) sheep prion protein variants.
Journal of neurochemistry 2007;103(6):2291-300.
2007: Gabriele Pöpperl; Friedrich W Kreth; Jan H Mehrkens; Jochen Herms; Klaus Seelos; Walter Koch; Franz-Josef Gildehaus; Hans A Kretzschmar; Jörg C Tonn; Klaus Tatsch
FET PET for the evaluation of untreated gliomas: correlation of FET uptake and uptake kinetics with tumour grading.
European journal of nuclear medicine and molecular imaging 2007;34(12):1933-42.
2007: Eva Grasbon-Frodl; Friedrich W Kreth; Michael Ruiter; Oliver Schnell; Karl Bise; Jörg Felsberg; Guido Reifenberger; Jörg-Christian Tonn; Hans A Kretzschmar
Intratumoral homogeneity of MGMT promoter hypermethylation as demonstrated in serial stereotactic specimens from anaplastic astrocytomas and glioblastomas.
International journal of cancer. Journal international du cancer 2007;121(11):2458-64.
2007: Silvio Notari; Sabina Capellari; Jan Langeveld; Armin Giese; Rosaria Strammiello; Pierluigi Gambetti; Hans A Kretzschmar; Piero Parchi
A refined method for molecular typing reveals that co-occurrence of PrP(Sc) types in Creutzfeldt-Jakob disease is not the rule.
Laboratory investigation; a journal of technical methods and pathology 2007;87(11):1103-12.
2007: Christian Freichel; Manuela Neumann; Theresa M Ballard; Veronika Müller; Marie Woolley; Laurence Ozmen; Edilio Borroni; Hans A Kretzschmar; Christian Haass; Will Spooren; Philipp J Kahle
Age-dependent cognitive decline and amygdala pathology in alpha-synuclein transgenic mice.
Neurobiology of aging 2007;28(9):1421-35.
2007: Uta Heinemann; Anna Krasnianski; Bettina Meissner; Sara Friederike Gloeckner; Hans A Kretzschmar; Inga Zerr
Molecular subtype-specific clinical diagnosis of prion diseases.
Veterinary microbiology 2007;123(4):328-35.
2007: Petra Frick; Armin Giese; Niklas Piening; Gerda Mitteregger; Achim Thomzig; Michael Beekes; Hans A Kretzschmar
Generation of genuine prion infectivity by serial PMCA.
Veterinary microbiology 2007;123(4):346-57.
2007: Andreas Weiss; Pablo del Pino; Uwe Bertsch; Christian Renner; Matthias Mentler; Klaus Grantner; Luis Moroder; Hans A Kretzschmar; Fritz G Parak
The configuration of the Cu(2+) binding region in full-length human prion protein compared with the isolated octapeptide.
Veterinary microbiology 2007;123(4):358-66.
2007: Karin M Danzer; Dorothea Haasen; Anne R Karow; Simon Moussaud; Matthias Habeck; Armin Giese; Hans A Kretzschmar; Bastian Hengerer; Marcus Kostka
Different species of alpha-synuclein oligomers induce calcium influx and seeding.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(34):9220-32.
2007: Runa Hamid; Ellen Kilger; Michael Willem; Neville Vassallo; Markus Kostka; Carsten Bornhövd; Andreas S Reichert; Hans A Kretzschmar; Christian Haass; Jochen Herms
Amyloid precursor protein intracellular domain modulates cellular calcium homeostasis and ATP content.
Journal of neurochemistry 2007;102(4):1264-75.
2007: Bjarne Krebs; Benedikt Bader; Juliane Klehmet; Eva Grasbon-Frodl; Wolfgang H Oertel; Inga Zerr; Sarah Stricker; Rolf Zschenderlein; Hans A Kretzschmar
A novel subtype of Creutzfeldt-Jakob disease characterized by a small 6 kDa PrP fragment.
Acta neuropathologica 2007;114(2):195-9.
2007: Wei Xiang; Manuela Hummel; Gerda Mitteregger; Claudia Pace; Otto Windl; Ulrich Mansmann; Hans A Kretzschmar
Transcriptome analysis reveals altered cholesterol metabolism during the neurodegeneration in mouse scrapie model.
Journal of neurochemistry 2007;102(3):834-47.
2007: Chantal Zuber; Gerda Mitteregger; Claudia Pace; Inga Zerr; Hans A Kretzschmar; Stefan Weiss
Anti-LRP/LR antibody W3 hampers peripheral PrPSc propagation in scrapie infected mice.
Prion 2007;1(3):207-12.
2007: Nigel J Cairns; Manuela Neumann; Eileen H Bigio; Ida E Holm; Dirk Troost; Kimmo J Hatanpaa; Chan Foong; Charles L White; Julie A Schneider; Hans A Kretzschmar; Deborah Carter; Lisa Taylor-Reinwald; Katherine Paulsmeyer; Jeffrey Strider; Michael Gitcho; Alison Goate; John C Morris; Manjari Mishra; Linda K Kwong; Anna Stieber; Yan Xu; Mark S Forman; John Q Trojanowski; Virginia M-Y Lee; Ian R A Mackenzie
TDP-43 in familial and sporadic frontotemporal lobar degeneration with ubiquitin inclusions.
The American journal of pathology 2007;171(1):227-40.
2007: Isidro Ferrer; Judith Armstrong; Sabina Capellari; Piero Parchi; Thomas Arzberger; Jeanne Bell; Herbert Budka; Thomas Ströbel; Giorgio Giaccone; Giacomina Rossi; Nenad Bogdanovic; Peter Fakai; Andrea Schmitt; Peter Riederers; Safa Al-Sarraj; Rivka Ravid; Hans A Kretzschmar
Effects of formalin fixation, paraffin embedding, and time of storage on DNA preservation in brain tissue: a BrainNet Europe study.
Brain pathology (Zurich, Switzerland) 2007;17(3):297-303.
2007: Martin Fuhrmann; Gerda Mitteregger; Hans A Kretzschmar; Jochen Herms
Dendritic pathology in prion disease starts at the synaptic spine.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2007;27(23):6224-33.
2007: Henriette J Tschampa; Kai Kallenberg; Hans A Kretzschmar; Bettina Meissner; Michael Knauth; Horst Urbach; Inga Zerr
Pattern of cortical changes in sporadic Creutzfeldt-Jakob disease.
AJNR. American journal of neuroradiology 2007;28(6):1114-8.
2007: Uta Heinemann; Anna Krasnianski; Bettina Meissner; Daniela Varges; Kai Kallenberg; Walter Schulz-Schaeffer; Bernhard J Steinhoff; E M Grasbon-Frodl; Hans A Kretzschmar; Inga Zerr
Creutzfeldt-Jakob disease in Germany: a prospective 12-year surveillance.
Brain : a journal of neurology 2007;130(Pt 5):1350-9.
2007: Ian R A Mackenzie; Eileen H Bigio; Paul Geoffrey Ince; Felix Geser; Manuela Neumann; Nigel J Cairns; Linda K Kwong; Mark S Forman; John Ravits; Heather Stewart; Andrew Eisen; Leo McClusky; Hans A Kretzschmar; Camelia M Monoranu; J Robin Highley; Janine Kirby; Teepu Siddique; Pamela J Shaw; Virginia M-Y Lee; John Q Trojanowski
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations.
Annals of neurology 2007;61(5):427-34.
2007: Manuela Neumann; Lionel Igaz; Linda K Kwong; Hanae Nakashima-Yasuda; Stephen J Kolb; Gideon Dreyfuss; Hans A Kretzschmar; John Q Trojanowski; Virginia M-Y Lee
Absence of heterogeneous nuclear ribonucleoproteins and survival motor neuron protein in TDP-43 positive inclusions in frontotemporal lobar degeneration.
Acta neuropathologica 2007;113(5):543-8.
2007: Shneh Sethi; Kristen M Kerksiek; Thomas Brocker; Hans A Kretzschmar
Role of the CD8+ dendritic cell subset in transmission of prions.
Journal of virology 2007;81(9):4877-80.
2007: Gerda Mitteregger; Milan R Vosko; Bjarne Krebs; Wei Xiang; Veronika Kohlmannsperger; Svenja Nölting; Gerhard F Hamann; Hans A Kretzschmar
The role of the octarepeat region in neuroprotective function of the cellular prion protein.
Brain pathology (Zurich, Switzerland) 2007;17(2):174-83.
2007: Rainer Seitz; Friedger von Auer; Johannes Blümel; Reinhard Burger; Anne Buschmann; Klaus Dietz; Margarethe Heiden; Walter E Hitzler; Horst Klamm; Thomas Kreil; Hans A Kretzschmar; Micha Nübling; Ruth Offergeld; Georg Pauli; Volkmar Schottstedt; Peter Volkers; Inga Zerr
Impact of vCJD on blood supply.
Biologicals : journal of the International Association of Biological Standardization 2007;35(2):79-97.
2007: Niclas W Schiffer; Sarah A Broadley; Thomas Hirschberger; Paul Tavan; Hans A Kretzschmar; Armin Giese; Christian Haass; F Ulrich Hartl; Bettina Schmid
Identification of anti-prion compounds as efficient inhibitors of polyglutamine protein aggregation in a zebrafish model.
The Journal of biological chemistry 2007;282(12):9195-203.
2007: Manuela Neumann; Linda K Kwong; Adam C Truax; Ben Vanmassenhove; Hans A Kretzschmar; Vivianna M Van Deerlin; Christopher M Clark; Murray Grossman; Bruce L Miller; John Q Trojanowski; Virginia M-Y Lee
TDP-43-positive white matter pathology in frontotemporal lobar degeneration with ubiquitin-positive inclusions.
Journal of neuropathology and experimental neurology 2007;66(3):177-83.
2007: Pablo del Pino; Andreas Weiss; Uwe Bertsch; Christian Renner; Matthias Mentler; Klaus Grantner; Ferdinando Fiorino; Wolfram Meyer-Klaucke; Luis Moroder; Hans A Kretzschmar; Fritz G Parak
The configuration of the Cu2+ binding region in full-length human prion protein.
European biophysics journal : EBJ 2007;36(3):239-52.
2007: Manuela Neumann; Ian R A Mackenzie; Nigel J Cairns; Philip J Boyer; William R Markesbery; Charles D Smith; J. Paul Taylor; Hans A Kretzschmar; Virginia E Kimonis; Mark S Forman
TDP-43 in the ubiquitin pathology of frontotemporal dementia with VCP gene mutations.
Journal of neuropathology and experimental neurology 2007;66(2):152-7.
2007: Petra Sostak; Diethilde Theil; Herbert Stepp; Sigrun Roeber; Hans A Kretzschmar; Andreas Straube
Detection of bone marrow-derived cells expressing a neural phenotype in the human brain.
Journal of neuropathology and experimental neurology 2007;66(2):110-6.
2007: Christina Priller; Ilse Dewachter; Neville Vassallo; Sandra Paluch; Claudia Pace; Hans A Kretzschmar; Fred Van Leuven; Jochen Herms
Mutant presenilin 1 alters synaptic transmission in cultured hippocampal neurons.
The Journal of biological chemistry 2007;282(2):1119-27.
2007: Isabella Wagner; Shneh Sethi; Wei Xiang; Armin Giese; Susanne Ebner; Hans A Kretzschmar
Repeated peripheral administrations of CpG oligodeoxynucleotides lead to sustained CNS immune activation.
Immunopharmacology and immunotoxicology 2007;29(3-4):413-24.
2007: Brit Mollenhauer; Petra Steinacker; Erik Bahn; Mirko Bibl; Peter Brechlin; Michael G Schlossmacher; Joseph J Locascio; Jens Wiltfang; Hans A Kretzschmar; Sigrid Poser; Claudia Trenkwalder; Markus Otto
Serum heart-type fatty acid-binding protein and cerebrospinal fluid tau: marker candidates for dementia with Lewy bodies.
Neuro-degenerative diseases 2007;4(5):366-75.
2007: Bjarne Krebs; Antje Wiebelitz; Beate Balitzki-Korte; Neville Vassallo; Sandra Paluch; Gerda Mitteregger; Takashi Onodera; Hans A Kretzschmar; Jochen Herms
Cellular prion protein modulates the intracellular calcium response to hydrogen peroxide.
Journal of neurochemistry 2007;100(2):358-67.
2007: Isidro Ferrer; Gabriel Santpere; Thomas Arzberger; Jeanne Bell; Rosa Blanco; Susana Boluda; Herbert Budka; Margarita Carmona; Giorgio Giaccone; Bjarne Krebs; Lucia Limido; Piero Parchi; Berta Puig; Rosaria Strammiello; Thomas Ströbel; Hans A Kretzschmar
Brain protein preservation largely depends on the postmortem storage temperature: implications for study of proteins in human neurologic diseases and management of brain banks: a BrainNet Europe Study.
Journal of neuropathology and experimental neurology 2007;66(1):35-46.
2007: A Schmitt; Martin Bauer; Helmut Heinsen; W Feiden; Peter Falkai; Irina Alafuzoff; Thomas Arzberger; Safa Al-Sarraj; J E Bell; Nenad Bogdanovic; W Brück; Herbert Budka; Isidro Ferrer; Giorgio Giaccone; Gabor Geza Kovacs; David Meyronet; Miklós Palkovits; Piero Parchi; Efstratios Patsouris; Rivka Ravid; R Reynolds; Peter Riederer; Wolfgang Roggendorf; Ameli Schwalber; Danielle Seilhean; Hans A Kretzschmar
How a neuropsychiatric brain bank should be run: a consensus paper of Brainnet Europe II.
Journal of neural transmission (Vienna, Austria : 1996) 2007;114(5):527-37.
2007: Lukas Cepek; Peter Brechlin; Petra Steinacker; Brit Mollenhauer; Enrico Klingebiel; Mirko Bibl; Hans A Kretzschmar; Jens Wiltfang; Markus Otto
Proteomic analysis of the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Dementia and geriatric cognitive disorders 2007;23(1):22-8.
2006: Alexander Pfeifer; Sabina Eigenbrod; Saba Al-Khadra; Andreas Hofmann; Gerda Mitteregger; Markus Moser; Uwe Bertsch; Hans A Kretzschmar
Lentivector-mediated RNAi efficiently suppresses prion protein and prolongs survival of scrapie-infected mice.
The Journal of clinical investigation 2006;116(12):3204-10.
2006: Marc Wermke; Stefan J Teipel; Thomas Fuchsberger; Hans A Kretzschmar; Ingo Westner; Mira Schröder; Harald Hampel; Alexander Drzezga
Frontal diaschisis in a German case of fatal familial insomnia.
Journal of neurology 2006;253(11):1510-2.
2006: Petra Frick; Armin Giese; Niklas Piening; Gerda Mitteregger; Achim Thomzig; Michael Beekes; Hans A Kretzschmar
Cell-free formation of misfolded prion protein with authentic prion infectivity.
Proceedings of the National Academy of Sciences of the United States of America 2006;103(43):15818-23.
2006: Manuela Neumann; Deepak M Sampathu; Linda K Kwong; Adam C Truax; Matthew Micsenyi; Thomas T Chou; Jennifer Bruce; Theresa Schuck; Murray Grossman; Christopher M Clark; Leo McCluskey; Bruce L Miller; Eliezer Masliah; Ian R A Mackenzie; Howard Feldman; Wolfgang Feiden; Hans A Kretzschmar; John Q Trojanowski; Virginia M-Y Lee
Ubiquitinated TDP-43 in frontotemporal lobar degeneration and amyotrophic lateral sclerosis.
Science (New York, N.Y.) 2006;314(5796):130-3.
2006: C Vollmert; Otto Windl; Wei Xiang; Albert Rosenberger; I Zerr; H-E Wichmann; Heike Bickeböller; Thomas Illig; Hans A Kretzschmar
Significant association of a M129V independent polymorphism in the 5' UTR of the PRNP gene with sporadic Creutzfeldt-Jakob disease in a large German case-control study.
Journal of medical genetics 2006;43(10):e53.
2006: Heiko Braak; Irina Alafuzoff; Thomas Arzberger; Hans A Kretzschmar; Kelly Del Tredici
Staging of Alzheimer disease-associated neurofibrillary pathology using paraffin sections and immunocytochemistry.
Acta neuropathologica 2006;112(4):389-404.
2006: Christian Behrends; Carola A Langer; Raina Boteva; Ulrike M K Böttcher; Markus J Stemp; Gregor Schaffar; Bharathi Vasudeva Rao; Armin Giese; Hans A Kretzschmar; Katja Siegers; F Ulrich Hartl
Chaperonin TRiC promotes the assembly of polyQ expansion proteins into nontoxic oligomers.
Molecular cell 2006;23(6):887-97.
2006: Martin Fuhrmann; Tobias Bittner; Gerda Mitteregger; Nicole Haider; Sven Moosmang; Hans A Kretzschmar; Jochen Herms
Loss of the cellular prion protein affects the Ca2+ homeostasis in hippocampal CA1 neurons.
Journal of neurochemistry 2006;98(6):1876-85.
2006: Michael Hamacher; Rolf Apweiler; Georg Arnold; Albert Becker; Martin Blüggel; Odile Carrette; Christine Colvis; Michael J Dunn; Thomas Fröhlich; Michael Fountoulakis; André van Hall; Friedrich Herberg; Jianguo Ji; Juango Ji; Hans A Kretzschmar; Piotr Lewczuk; Gert Lubec; Katrin Marcus; Lennart Martens; Nadine Palacios Bustamante; Young Mok Park; Stephen R Pennington; Johan Robben; Kai Stühler; Kai A Reidegeld; Peter Riederer; Jean Rossier; jean-charles sanchez; Michael Schrader; Christian Stephan; Danilo Tagle; Herbert Thiele; Jing Wang; Jens Wiltfang; Jong Shin Yoo; Chenggang Zhang; Joachim Klose; Helmut E Meyer
HUPO Brain Proteome Project: summary of the pilot phase and introduction of a comprehensive data reprocessing strategy.
Proteomics 2006;6(18):4890-8.
2006: Thomas Fröhlich; Derrick Helmstetter; Monica Zobawa; Anna C Crecelius; Thomas Arzberger; Hans A Kretzschmar; Georg J Arnold
Analysis of the HUPO Brain Proteome reference samples using 2-D DIGE and 2-D LC-MS/MS.
Proteomics 2006;6(18):4950-66.
2006: Anna Krasnianski; Walter Schulz-Schaeffer; Kai Kallenberg; Bettina Meissner; Donald A Collie; Sigrun Roeber; Mario Bartl; Uta Heinemann; Daniela Varges; Hans A Kretzschmar; Inga Zerr
Clinical findings and diagnostic tests in the MV2 subtype of sporadic CJD.
Brain : a journal of neurology 2006;129(Pt 9):2288-96.
2006: Irina Alafuzoff; Maria Pikkarainen; Safa Al-Sarraj; Thomas Arzberger; Jeanne Bell; Istvan Bodi; Nenad Bogdanovic; Herbert Budka; Orso Bugiani; Isidro Ferrer; Ellen Gelpi; Giorgio Giaccone; Manuel B Graeber; JEAN-JACQUES HAUW; Wouter Kamphorst; Andrew King; Nicolas Kopp; Penelope Korkolopoulou; Gabor Geza Kovacs; David Meyronet; Piero Parchi; Efstratios Patsouris; Matthias Preusser; Rivka Ravid; Wolfgang Roggendorf; Danielle Seilhean; Nathalie Streichenberger; Dietmar R Thal; Hans A Kretzschmar
Interlaboratory comparison of assessments of Alzheimer disease-related lesions: a study of the BrainNet Europe Consortium.
Journal of neuropathology and experimental neurology 2006;65(8):740-57.
2006: A-M Shiarli; R Jennings; Jing Shi; K Bailey; Yvonne Davidson; Jinzhou Tian; Eileen H Bigio; Bernardino Ghetti; Jill R Murrell; Marie-Bernadette Delisle; Suzanne S Mirra; Barbara J Crain; P Zolo; K Arima; E Iseki; S Murayama; Hans A Kretzschmar; M Neumann; Carol F Lippa; G Halliday; J Mackenzie; N Khan; Rivka Ravid; dennis dickson; Zbigniew K Wszolek; Takeshi Iwatsubo; Stuart Pickering-Brown; D M A Mann
Comparison of extent of tau pathology in patients with frontotemporal dementia with Parkinsonism linked to chromosome 17 (FTDP-17), frontotemporal lobar degeneration with Pick bodies and early onset Alzheimer's disease.
Neuropathology and applied neurobiology 2006;32(4):374-87.
2006: Christina Priller; Thomas Bauer; Gerda Mitteregger; Bjarne Krebs; Hans A Kretzschmar; Jochen Herms
Synapse formation and function is modulated by the amyloid precursor protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2006;26(27):7212-21.
2006: Sigrun Roeber; Hansjoerg Bäzner; Michael Hennerici; Romy Porstmann; Hans A Kretzschmar
Neurodegeneration with features of NIFID and ALS--extended clinical and neuropathological spectrum.
Brain pathology (Zurich, Switzerland) 2006;16(3):228-34.
2006: Niklas Piening; Petra Frick; Tobias Högen; Michael Beekes; Hans A Kretzschmar; Armin Giese
Photo-induced crosslinking of prion protein oligomers and prions.
Amyloid : the international journal of experimental and clinical investigation : the official journal of the International Society of Amyloidosis 2006;13(2):67-77.
2006: Anna Krasnianski; Bettina Meissner; Walter Schulz-Schaeffer; Kai Kallenberg; Mario Bartl; Uta Heinemann; Daniela Varges; Hans A Kretzschmar; Inga Zerr
Clinical features and diagnosis of the MM2 cortical subtype of sporadic Creutzfeldt-Jakob disease.
Archives of neurology 2006;63(6):876-80.
2006: Bjarne Krebs; Veronika Kohlmannsperger; Svenja Nölting; Rüdiger Schmalzbauer; Hans A Kretzschmar
A method to perform Western blots of microscopic areas of histological sections.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(5):559-65.
2006: Niklas Piening; Romolo Nonno; Michele Angelo Di Bari; Stephanie Walter; Otto Windl; Umberto Agrimi; Hans A Kretzschmar; Uwe Bertsch
Conversion efficiency of bank vole prion protein in vitro is determined by residues 155 and 170, but does not correlate with the high susceptibility of bank voles to sheep scrapie in vivo.
The Journal of biological chemistry 2006;281(14):9373-84.
2006: Kathrin Barnewitz; Marko Maringer; Gerda Mitteregger; Armin Giese; Uwe Bertsch; Hans A Kretzschmar
Unaltered prion protein cleavage in plasminogen-deficient mice.
Neuroreport 2006;17(5):527-30.
2006: Rohan de Silva; Tammaryn Lashley; Catherine Strand; Anna-Maria Shiarli; Jing Shi; Jinzhou Tian; Kathryn L Bailey; Peter Davies; Eileen H Bigio; Kunimasa Arima; Eizo Iseki; Shigeo Murayama; Hans A Kretzschmar; Manuela Neumann; Carol F Lippa; Glenda Halliday; James MacKenzie; Rivka Ravid; dennis dickson; Zbigniew K Wszolek; Takeshi Iwatsubo; Stuart Pickering-Brown; Janice Holton; Andrew J Lees; Tamas Revesz; D M A Mann
An immunohistochemical study of cases of sporadic and inherited frontotemporal lobar degeneration using 3R- and 4R-specific tau monoclonal antibodies.
Acta neuropathologica 2006;111(4):329-40.
2006: Gabriele Pöpperl; Friedrich W Kreth; Jochen Herms; Walter Koch; Jan H Mehrkens; Franz-Josef Gildehaus; Hans A Kretzschmar; Jörg-Christian Tonn; Klaus Tatsch
Analysis of 18F-FET PET for grading of recurrent gliomas: is evaluation of uptake kinetics superior to standard methods?
Journal of nuclear medicine : official publication, Society of Nuclear Medicine 2006;47(3):393-403.
2006: Bjarne Krebs; Cornelia Dorner-Ciossek; Rüdiger Schmalzbauer; Neville Vassallo; Jochen Herms; Hans A Kretzschmar
Prion protein induced signaling cascades in monocytes.
Biochemical and biophysical research communications 2006;340(1):13-22.
2006: Constanze Boesenberg-Grosse; Walter Schulz-Schaeffer; Monika Bodemer; Barbara Ciesielczyk; Bettina Meissner; Anna Krasnianski; Mario Bartl; Uta Heinemann; Daniela Varges; Sabina Eigenbrod; Hans A Kretzschmar; Alison Green; Inga Zerr
Brain-derived proteins in the CSF: do they correlate with brain pathology in CJD?
BMC neurology 2006;6():35.
2006: Katharina Buerger; Markus Otto; Stefan J Teipel; Raymond Zinkowski; Kaj Blennow; John DeBernardis; Daniel Kerkman; Johannes Schröder; Peter Schönknecht; Lukas Cepek; Cheryl McCulloch; Hans-Jürgen Möller; Jens Wiltfang; Hans A Kretzschmar; Harald Hampel
Dissociation between CSF total tau and tau protein phosphorylated at threonine 231 in Creutzfeldt-Jakob disease.
Neurobiology of aging 2006;27(1):10-5.
2005: Otto Windl; Malte Buchholz; Antonie Neubauer; Walter Schulz-Schaeffer; Martin H Groschup; S Walter; S Arendt; M Neumann; A K Voss; Hans A Kretzschmar
Breaking an absolute species barrier: transgenic mice expressing the mink PrP gene are susceptible to transmissible mink encephalopathy.
Journal of virology 2005;79(23):14971-5.
2005: Bettina Meissner; Ingo M Westner; Kai Kallenberg; Anna Krasnianski; Mario Bartl; Daniela Varges; C Bösenberg; Hans A Kretzschmar; Michael Knauth; Walter Schulz-Schaeffer; Inga Zerr
Sporadic Creutzfeldt-Jakob disease: clinical and diagnostic characteristics of the rare VV1 type.
Neurology 2005;65(10):1544-50.
2005: Gabor Geza Kovacs; Maria Puopolo; Anna Ladogana; Maurizio Pocchiari; Herbert Budka; C.M. Duijn; Steven J Collins; Alison Boyd; Antonio Giulivi; Michael B Coulthart; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; Inga Zerr; Hans A Kretzschmar; Jesús de Pedro-Cuesta; Miguel Calero-Lara; Markus Glatzel; Adriano Aguzzi; Matthew Bishop; Richard Knight; Girma Belay; Robert Will; Eva Mitrova
Genetic prion disease: the EUROCJD experience.
Human genetics 2005;118(2):166-74.
2005: Constanze Boesenberg; Walter Schulz-Schaeffer; Bettina Meissner; Kai Kallenberg; Mario Bartl; Uta Heinemann; Anna Krasnianski; Katharina Stoeck; Daniela Varges; Otto Windl; Hans A Kretzschmar; Inga Zerr
Clinical course in young patients with sporadic Creutzfeldt-Jakob disease.
Annals of neurology 2005;58(4):533-43.
2005: Henriette J Tschampa; Kai Kallenberg; Horst Urbach; Bettina Meissner; Claudia Nicolay; Hans A Kretzschmar; Michael Knauth; Inga Zerr
MRI in the diagnosis of sporadic Creutzfeldt-Jakob disease: a study on inter-observer agreement.
Brain : a journal of neurology 2005;128(Pt 9):2026-33.
2005: Armin Giese; Benedikt Bader; Jan Bieschke; Gregor Schaffar; Sabine Odoy; Philipp J Kahle; Christian Haass; Hans A Kretzschmar
Single particle detection and characterization of synuclein co-aggregation.
Biochemical and biophysical research communications 2005;333(4):1202-10.
2005: Wei Xiang; Otto Windl; Ingo M Westner; Manuela Neumann; Inga Zerr; Rosa M Lederer; Hans A Kretzschmar
Cerebral gene expression profiles in sporadic Creutzfeldt-Jakob disease.
Annals of neurology 2005;58(2):242-57.
2005: Manuela Neumann; M Mittelbronn; P Simon; Ben Vanmassenhove; R de Silva; Andrew J Lees; J Klapp; R Meyermann; Hans A Kretzschmar
A new family with frontotemporal dementia with intronic 10+3 splice site mutation in the tau gene: neuropathology and molecular effects.
Neuropathology and applied neurobiology 2005;31(4):362-73.
2005: Ronald Albrecht; B Krebs; E Reusche; M Nagel; Rebekka Lencer; Hans A Kretzschmar
Signs of rapidly progressive dementia in a case of intravascular lymphomatosis.
European archives of psychiatry and clinical neuroscience 2005;255(4):232-5.
2005: Harald Hampel; Andreas Haslinger; Michael Scheloske; Frank Padberg; Petra Fischer; Josef Unger; Stefan J Teipel; Michaela Neumann; Carlyn Rosenberg; Rusti Oshida; Christine M Hulette; Dieter Pongratz; Michael Ewers; Hans A Kretzschmar; Hans-Jürgen Möller
Pattern of interleukin-6 receptor complex immunoreactivity between cortical regions of rapid autopsy normal and Alzheimer's disease brain.
European archives of psychiatry and clinical neuroscience 2005;255(4):269-78.
2005: Brit Mollenhauer; Mirko Bibl; Claudia Trenkwalder; Gerthild Stiens; Lukas Cepek; Petra Steinacker; Barbara Ciesielczyk; Karin Neubert; Jens Wiltfang; Hans A Kretzschmar; Sigrid Poser; Markus Otto
Follow-up investigations in cerebrospinal fluid of patients with dementia with Lewy bodies and Alzheimer's disease.
Journal of neural transmission (Vienna, Austria : 1996) 2005;112(7):933-48.
2005: Nikolaus Ivo Sarafoff; Jan Bieschke; Armin Giese; Petra Frick; Uwe Bertsch; Hans A Kretzschmar
Automated PrPres amplification using indirect sonication.
Journal of biochemical and biophysical methods 2005;63(3):213-21.
2005: Neville Vassallo; Jochen Herms; Christina Behrens; Bjarne Krebs; Keiichi Saeki; Takashi Onodera; Otto Windl; Hans A Kretzschmar
Activation of phosphatidylinositol 3-kinase by cellular prion protein and its role in cell survival.
Biochemical and biophysical research communications 2005;332(1):75-82.
2005: Uwe Bertsch; Konstanze F Winklhofer; Thomas Hirschberger; Jan Bieschke; Petra Frick; F Ulrich Hartl; Paul Tavan; Jörg Tatzelt; Hans A Kretzschmar; Armin Giese
Systematic identification of antiprion drugs by high-throughput screening based on scanning for intensely fluorescent targets.
Journal of virology 2005;79(12):7785-91.
2005: Anna Ladogana; Maria Puopolo; Esther Croes; Herbert Budka; Christa Jarius; Steven Collins; Genevieve M Klug; T Sutcliffe; Antonio Giulivi; A Alperovitch; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; Sigrid Poser; Hans A Kretzschmar; I Rietveld; Eva Mitrova; J de Pedro Cuesta; P Martinez-Martin; Markus Glatzel; Adriano Aguzzi; Richard Knight; H Ward; Maurizio Pocchiari; C.M. Duijn; Robert G Will; Inga Zerr
Mortality from Creutzfeldt-Jakob disease and related disorders in Europe, Australia, and Canada.
Neurology 2005;64(9):1586-91.
2005: Bjarne Krebs; Rosa-Maria Lederer; Otto Windl; Eva Grasbon-Frodl; Inga Zerr; Hans A Kretzschmar
Creutzfeldt-Jakob disease associated with an R148H mutation of the prion protein gene.
Neurogenetics 2005;6(2):97-100.
2005: Manuela Neumann; Silvia Diekmann; Uwe Bertsch; Ben Vanmassenhove; Bernhard Bogerts; Hans A Kretzschmar
Novel G335V mutation in the tau gene associated with early onset familial frontotemporal dementia.
Neurogenetics 2005;6(2):91-5.
2005: Johannes Levin; Uwe Bertsch; Hans A Kretzschmar; Armin Giese
Single particle analysis of manganese-induced prion protein aggregates.
Biochemical and biophysical research communications 2005;329(4):1200-7.
2005: Vera Carina Zingler; Michael Strupp; Klaus Jahn; Miriam Glaser; Simone Herberger; Hans A Kretzschmar; Thomas Brandt
Upbeat nystagmus as the initial clinical sign of Creutzfeldt-Jakob disease.
Annals of neurology 2005;57(4):607-8.
2005: Sigrun Roeber; Bjarne Krebs; Manuela Neumann; Otto Windl; Inga Zerr; Eva Grasbon-Frodl; Hans A Kretzschmar
Creutzfeldt-Jakob disease in a patient with an R208H mutation of the prion protein gene (PRNP) and a 17-kDa prion protein fragment.
Acta neuropathologica 2005;109(4):443-8.
2005: Martina Stork; Armin Giese; Hans A Kretzschmar; Paul Tavan
Molecular dynamics simulations indicate a possible role of parallel beta-helices in seeded aggregation of poly-Gln.
Biophysical journal 2005;88(4):2442-51.
2005: Stefan Bleich; Markus Otto; Inga Zerr; Stefan Kropp; Hans A Kretzschmar; Jens Wiltfang
Creutzfeldt-Jakob disease and homocysteine levels in plasma and cerebrospinal fluid.
Gerontology 2005;51(2):142-4.
2005: Christian Jacobi; Sönke Arlt; Hansotto Reiber; Ingo M Westner; Hans A Kretzschmar; Sigrid Poser; Inga Zerr
Immunoglobulins and virus-specific antibodies in patients with Creutzfeldt-Jakob disease.
Acta neurologica Scandinavica 2005;111(3):185-90.
2005: Matthias Mentler; Andreas Weiss; Klaus Grantner; Pablo del Pino; Dominga Deluca; Stella Fiori; Christian Renner; Wolfram Meyer Klaucke; Luis Moroder; Uwe Bertsch; Hans A Kretzschmar; Paul Tavan; Fritz G Parak
A new method to determine the structure of the metal environment in metalloproteins: investigation of the prion protein octapeptide repeat Cu(2+) complex.
European biophysics journal : EBJ 2005;34(2):97-112.
2005: Christoph J Schankin; Tobias Birnbaum; Jennifer Linn; Roland Brüning; Hans A Kretzschmar; Andreas Straube; Bjarne Krebs
A fatal encephalitis.
Lancet 2005;365(9456):358.
2005: Niklas Piening; Petra Frick; Armin Giese; Hans A Kretzschmar
Breakage of PrP aggregates is essential for efficient autocatalytic propagation of misfolded prion protein.
Biochemical and biophysical research communications 2005;326(2):339-43.
2005: Armin Giese; Malte Buchholz; Jochen Herms; Hans A Kretzschmar
Mouse brain synaptosomes accumulate copper-67 efficiently by two distinct processes independent of cellular prion protein.
Journal of molecular neuroscience : MN 2005;27(3):347-54.
2005: Shneh Sethi; Susanne Ebner; C Hinske; Hans A Kretzschmar
Multiple administrations of oligodeoxynucleotides containing CpG motifs influence Ig isotype production.
Immunopharmacology and immunotoxicology 2005;27(3):447-60.
2005: Robert Perneczky; D Mösch; M Neumann; Hans A Kretzschmar; U Müller; R Busch; hans förstl; Alexander Kurz
The Alzheimer variant of lewy body disease: a pathologically confirmed case-control study.
Dementia and geriatric cognitive disorders 2005;20(2-3):89-94.
2005: Lukas Cepek; Petra Steinacker; Brit Mollenhauer; Birgitt Wiese; Barbara Ciesielczyk; Mirko Bibl; Jens Wiltfang; Inga Zerr; Walter Schulz-Schaeffer; Hans A Kretzschmar; Sigrid Poser; Markus Otto
Follow-up investigations of tau protein and S-100B levels in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Dementia and geriatric cognitive disorders 2005;19(5-6):376-82.
2005: Brit Mollenhauer; Lukas Cepek; Mirko Bibl; Jens Wiltfang; Walter Schulz-Schaeffer; Barbara Ciesielczyk; Manuela Neumann; Petra Steinacker; Hans A Kretzschmar; Sigrid Poser; Claudia Trenkwalder; Markus Otto
Tau protein, Abeta42 and S-100B protein in cerebrospinal fluid of patients with dementia with Lewy bodies.
Dementia and geriatric cognitive disorders 2005;19(2-3):164-70.
2004: Bettina Drisaldi; Janaky Coomaraswamy; Peter Mastrangelo; Bob Strome; Jing Yang; Joel C Watts; M Azhar Chishti; Melissa Marvi; Otto Windl; Rosemary Ahrens; François Major; Man-Sun Sy; Hans A Kretzschmar; Paul E Fraser; Howard T J Mount; David Westaway
Genetic mapping of activity determinants within cellular prion proteins: N-terminal modules in PrPC offset pro-apoptotic activity of the Doppel helix B/B' region.
The Journal of biological chemistry 2004;279(53):55443-54.
2004: Manuela Neumann; Veronika Müller; Hans A Kretzschmar; Christian Haass; Philipp J Kahle
Regional distribution of proteinase K-resistant alpha-synuclein correlates with Lewy body disease stage.
Journal of neuropathology and experimental neurology 2004;63(12):1225-35.
2004: Eva Grasbon-Frodl; Holger Lorenz; U Mann; Roger M Nitsch; Otto Windl; Hans A Kretzschmar
Loss of glycosylation associated with the T183A mutation in human prion disease.
Acta neuropathologica 2004;108(6):476-84.
2004: Eva Grasbon-Frodl; Rüdiger Schmalzbauer; Petra Frick; Bjarne Krebs; Otto Windl; Inga Zerr; Hans A Kretzschmar
A novel three extra-repeat insertion in the prion protein gene (PRNP) in a patient with Creutzfeldt-Jakob disease.
Neurogenetics 2004;5(4):249-50.
2004: Inga Zerr; Monika Bodemer; Ulrich Kaboth; Hans A Kretzschmar; Michael Oellerich; Victor W Armstrong
Plasminogen activities and concentrations in patients with sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 2004;371(2-3):163-6.
2004: Petra Steinacker; Brit Mollenhauer; Mirko Bibl; Lukas Cepek; Hermann Esselmann; Peter Brechlin; Piotr Lewczuk; Sigrid Poser; Hans A Kretzschmar; Jens Wiltfang; Claudia Trenkwalder; Markus Otto
Heart fatty acid binding protein as a potential diagnostic marker for neurodegenerative diseases.
Neuroscience letters 2004;370(1):36-9.
2004: Bernhard J Steinhoff; Inga Zerr; Maya Glatting; Walter Schulz-Schaeffer; Sigrid Poser; Hans A Kretzschmar
Diagnostic value of periodic complexes in Creutzfeldt-Jakob disease.
Annals of neurology 2004;56(5):702-8.
2004: Jochen Herms; Brigitte Anliker; Sabine Heber; Sabine Ring; Martin Fuhrmann; Hans A Kretzschmar; Sangram S Sisodia; Ulrike Müller
Cortical dysplasia resembling human type 2 lissencephaly in mice lacking all three APP family members.
The EMBO journal 2004;23(20):4106-15.
2004: Hans H Klünemann; Ekaterina Rogaeva; Manuela Neumann; Hans A Kretzschmar; Michael Kandel; Anna Toulina; Christine Sato; Shabnam Salehi-Rad; Karin Pfister; Helmfried E Klein; Peter St George-Hyslop
Novel PS1 mutation in a Bavarian kindred with familial Alzheimer disease.
Alzheimer disease and associated disorders 2004;18(4):256-8.
2004: U Schüller; F Schober; Hans A Kretzschmar; Jochen Herms
Bcl-2 expression inversely correlates with tumour cell differentiation in medulloblastoma.
Neuropathology and applied neurobiology 2004;30(5):513-21.
2004: Wei Xiang; Otto Windl; Gerda Wünsch; Martin Dugas; Alexander Kohlmann; Nicola Dierkes; Ingo M Westner; Hans A Kretzschmar
Identification of differentially expressed genes in scrapie-infected mouse brains by using global gene expression technology.
Journal of virology 2004;78(20):11051-60.
2004: Maurizio Pocchiari; Maria Puopolo; Esther Croes; Herbert Budka; Ellen Gelpi; Steven Collins; V Lewis; T Sutcliffe; A Guilivi; Nicole Delasnerie-Laupretre; Jean-Philippe Brandel; A Alperovitch; Inga Zerr; Sigrid Poser; Hans A Kretzschmar; Anna Ladogana; I Rietvald; Eva Mitrova; P Martinez-Martin; Jesús de Pedro-Cuesta; Markus Glatzel; Adriano Aguzzi; S Cooper; J Mackenzie; C.M. Duijn; Robert G Will
Predictors of survival in sporadic Creutzfeldt-Jakob disease and other human transmissible spongiform encephalopathies.
Brain : a journal of neurology 2004;127(Pt 10):2348-59.
2004: Jan Bieschke; Petra Frick; Nikolaus Sarafoff; Michael Beekes; Armin Giese; Hans A Kretzschmar
Autocatalytic self-propagation of misfolded prion protein.
Proceedings of the National Academy of Sciences of the United States of America 2004;101(33):12207-11.
2004: Bettina Meissner; K Körtner; Mario Bartl; Ute Jastrow; Brit Mollenhauer; Andreas Schröter; M Finkenstaedt; Otto Windl; Sigrid Poser; Hans A Kretzschmar; Inga Zerr
Sporadic Creutzfeldt-Jakob disease: magnetic resonance imaging and clinical findings.
Neurology 2004;63(3):450-6.
2004: Armin Giese; Johannes Levin; Uwe Bertsch; Hans A Kretzschmar
Effect of metal ions on de novo aggregation of full-length prion protein.
Biochemical and biophysical research communications 2004;320(4):1240-6.
2004: Matthias Riemenschneider; Norman Klopp; W Xiang; Stefan Wagenpfeil; C Vollmert; U Müller; hans förstl; Thomas Illig; Hans A Kretzschmar; Alexander Kurz
Prion protein codon 129 polymorphism and risk of Alzheimer disease.
Neurology 2004;63(2):364-6.
2004: Ozlem Ozen; Bjarne Krebs; Bernhard Hemmerlein; Arnulf Pekrun; Hans A Kretzschmar; Jochen Herms
Expression of matrix metalloproteinases and their inhibitors in medulloblastomas and their prognostic relevance.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(14):4746-53.
2004: A Harder; A Gregor; T Wirth; F Kreuz; Walter Schulz-Schaeffer; Otto Windl; Michail Plotkin; H Amthauer; K Neukirch; Hans A Kretzschmar; T Kuhlmann; R Braas; H H Hahne; K Jendroska
Early age of onset in fatal familial insomnia. Two novel cases and review of the literature.
Journal of neurology 2004;251(6):715-24.
2004: Manuela Neumann; Veronika Müller; Karin Görner; Hans A Kretzschmar; Christian Haass; Philipp J Kahle
Pathological properties of the Parkinson's disease-associated protein DJ-1 in alpha-synucleinopathies and tauopathies: relevance for multiple system atrophy and Pick's disease.
Acta neuropathologica 2004;107(6):489-96.
2004: Silvio Notari; Sabina Capellari; Armin Giese; Ingo Westner; Agostino Baruzzi; Bernardino Ghetti; Pierluigi Gambetti; Hans A Kretzschmar; Piero Parchi
Effects of different experimental conditions on the PrPSc core generated by protease digestion: implications for strain typing and molecular classification of CJD.
The Journal of biological chemistry 2004;279(16):16797-804.
2004: Gabor C Petzold; I Westner; Georg Bohner; Karl M Einhäupl; Hans A Kretzschmar; José Manuel Valdueza
False-positive pulvinar sign on MRI in sporadic Creutzfeldt-Jakob disease.
Neurology 2004;62(7):1235-6.
2004: Markus Otto; Lukas Cepek; Peter Ratzka; S Doehlinger; I Boekhoff; Jens Wiltfang; Eva Irle; G Pergande; B Ellers-Lenz; Otto Windl; Hans A Kretzschmar; Sigrid Poser; Hilmar Prange
Efficacy of flupirtine on cognitive function in patients with CJD: A double-blind study.
Neurology 2004;62(5):714-8.
2004: Christian Renner; Stella Fiori; Ferdinando Fiorino; Dirk Landgraf; Dominga Deluca; Matthias Mentler; Klaus Grantner; Fritz G Parak; Hans A Kretzschmar; Luis Moroder
Micellar environments induce structuring of the N-terminal tail of the prion protein.
Biopolymers 2004;73(4):421-33.
2004: Aurelia Peraud; Jochen Herms; Jürgen Schlegel; P Müller; Hans A Kretzschmar; Jörg-Christian Tonn
Recurrent spinal cord astrocytoma with intraventricular seeding.
Child's nervous system : ChNS : official journal of the International Society for Pediatric Neurosurgery 2004;20(2):114-8.
2004: H Schmidt; Markus Otto; Paul Dieter Niedmann; Lukas Cepek; Andreas Schröter; Hans A Kretzschmar; Sigrid Poser
CSF lactate dehydrogenase activity in patients with Creutzfeldt-Jakob disease exceeds that in other dementias.
Dementia and geriatric cognitive disorders 2004;17(3):204-6.
2003: Stefan Korte; Neville Vassallo; Michael L Kramer; Hans A Kretzschmar; Jochen Herms
Modulation of L-type voltage-gated calcium channels by recombinant prion protein.
Journal of neurochemistry 2003;87(4):1037-42.
2003: Alexander Hopt; Stefan Korte; Herbert Fink; Ulrich Panne; Reinhard Niessner; Reinhard Jahn; Hans A Kretzschmar; Jochen Herms
Methods for studying synaptosomal copper release.
Journal of neuroscience methods 2003;128(1-2):159-72.
2003: Jens Wiltfang; Hermann Esselmann; Alexandr Smirnov; Mirko Bibl; Lukas Cepek; Petra Steinacker; Brit Mollenhauer; Katharina Buerger; Harald Hampel; Sabine Paul; Manuela Neumann; Manuel Maler; Inga Zerr; Johannes Kornhuber; Hans A Kretzschmar; Sigrid Poser; Markus Otto
Beta-amyloid peptides in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Annals of neurology 2003;54(2):263-7.
2003: Hans A Kretzschmar; Shneh Sethi; Zsuzsanna Földvári; Otto Windl; Veronika Querner; Inga Zerr; Sigrid Poser
Latrogenic Creutzfeldt-Jakob disease with florid plaques.
Brain pathology (Zurich, Switzerland) 2003;13(3):245-9.
2003: Peter Ratzka; Susanne Döhlinger; Lukas Cepek; Petra Steinacker; Sönke Arlt; Christian Jacobi; Andreas Schröter; Jens Wiltfang; Hilmar Prange; Hans A Kretzschmar; Sigrid Poser; Markus Otto
Different binding pattern of antibodies to prion protein on lymphocytes from patients with sporadic Creutzfeldt-Jakob disease.
Neuroscience letters 2003;343(1):29-32.
2003: Hans A Kretzschmar
Diagnosis of prion diseases.
Clinics in laboratory medicine 2003;23(1):109-28, viii.
2003: Matthias Riemenschneider; Stefan Wagenpfeil; hugo vanderstichele; M Otto; J Wiltfang; Hans A Kretzschmar; Eugeen Vanmechelen; hans förstl; Alexander Kurz
Phospho-tau/total tau ratio in cerebrospinal fluid discriminates Creutzfeldt-Jakob disease from other dementias.
Molecular psychiatry 2003;8(3):343-7.
2003: Jochen Herms; Ilka Schneider; Ilse Dewachter; Nathalie Caluwaerts; Hans A Kretzschmar; Fred Van Leuven
Capacitive calcium entry is directly attenuated by mutant presenilin-1, independent of the expression of the amyloid precursor protein.
The Journal of biological chemistry 2003;278(4):2484-9.
2002: Manuela Neumann; Philipp J Kahle; Benoit I Giasson; Laurence Ozmen; Edilio Borroni; Will Spooren; Veronika Müller; Sabine Odoy; Hideo Fujiwara; Masato Hasegawa; Takeshi Iwatsubo; John Q Trojanowski; Hans A Kretzschmar; Christian Haass
Misfolded proteinase K-resistant hyperphosphorylated alpha-synuclein in aged transgenic mice with locomotor deterioration and in human alpha-synucleinopathies.
The Journal of clinical investigation 2002;110(10):1429-39.
2002: Henriette J Tschampa; Jochen Herms; Walter Schulz-Schaeffer; Brigitte Maruschak; Otto Windl; Ute Jastrow; Inga Zerr; Bernhard J Steinhoff; Sigrid Poser; Hans A Kretzschmar
Clinical findings in sporadic Creutzfeldt-Jakob disease correlate with thalamic pathology.
Brain : a journal of neurology 2002;125(Pt 11):2558-66.
2002: Philipp J Kahle; Christian Haass; Hans A Kretzschmar; Manuela Neumann
Structure/function of alpha-synuclein in health and disease: rational development of animal models for Parkinson's and related diseases.
Journal of neurochemistry 2002;82(3):449-57.
2002: Shneh Sethi; Grayson Lipford; Hermann Wagner; Hans A Kretzschmar
Postexposure prophylaxis against prion disease with a stimulator of innate immunity.
Lancet 2002;360(9328):229-30.
2002: Hans A Kretzschmar; W Feiden
[Human prion diseases].
Der Pathologe 2002;23(4):241-51.
2002: Hans A Kretzschmar
[Etiology, pathology and diagnosis of prion diseases in humans].
Der Internist 2002;43(6):716-22, 724-30.
2002: Philipp J Kahle; Manuela Neumann; Laurence Ozmen; Veronika Muller; Helmut Jacobsen; Will Spooren; Babette Fuss; Barbara S Mallon; Wendy B Macklin; Hideo Fujiwara; Masato Hasegawa; Takeshi Iwatsubo; Hans A Kretzschmar; Christian Haass
Hyperphosphorylation and insolubility of alpha-synuclein in transgenic mouse oligodendrocytes.
EMBO reports 2002;3(6):583-8.
2002: Herbert Budka; Dominique Dormont; Hans A Kretzschmar; Maurizio Pocchiari; C.M. Duijn
BSE and variant Creutzfeldt-Jakob disease: never say never.
Acta neuropathologica 2002;103(6):627-8.
2002: C Wegner; A Römer; Rüdiger Schmalzbauer; Holger Lorenz; Otto Windl; Hans A Kretzschmar
Mutant prion protein acquires resistance to protease in mouse neuroblastoma cells.
The Journal of general virology 2002;83(Pt 5):1237-45.
2002: Holger Lorenz; Otto Windl; Hans A Kretzschmar
Cellular phenotyping of secretory and nuclear prion proteins associated with inherited prion diseases.
The Journal of biological chemistry 2002;277(10):8508-16.
2002: Hayrettin Tumani; O Windl; Hans A Kretzschmar; A C Ludolph
[Clinically atypical CJD: diagnostic relevance of cerebrospinal fluid markers and molecular genetic analysis?].
Deutsche medizinische Wochenschrift (1946) 2002;127(7):318-20.
2002: Brit Mollenhauer; Inga Zerr; D Ruge; G Krause; W H Mehnert; Hans A Kretzschmar; Sigrid Poser
[Epidemiology and clinical symptomatology of Creutzfeldt-Jakob disease].
Deutsche medizinische Wochenschrift (1946) 2002;127(7):312-7.
2002: Markus Otto; Jens Wiltfang; Lukas Cepek; Manuela Neumann; Brit Mollenhauer; Petra Steinacker; Barbara Ciesielczyk; Walter Schulz-Schaeffer; Hans A Kretzschmar; Sigrid Poser
Tau protein and 14-3-3 protein in the differential diagnosis of Creutzfeldt-Jakob disease.
Neurology 2002;58(2):192-7.
2001: S Kastenbauer; W J Schulz-Schaeffer; K Tatsch; T A Yousry; Hans A Kretzschmar; H W Pfister
Crossed cerebellar diaschisis: a clue to the mechanism of ataxic hemiparesis in Creutzfeldt-Jakob disease?
Journal of neurology 2001;248(12):1093-5.
2001: Philipp J Kahle; Manuela Neumann; Laurence Ozmen; Veronika Müller; Sabine Odoy; N Okamoto; Helmut Jacobsen; Takeshi Iwatsubo; John Q Trojanowski; H Takahashi; K Wakabayashi; Nenad Bogdanovic; Peter Riederer; Hans A Kretzschmar; Christian Haass
Selective insolubility of alpha-synuclein in human Lewy body diseases is recapitulated in a transgenic mouse model.
The American journal of pathology 2001;159(6):2215-25.
2001: Jens Wiltfang; Hermann Esselmann; P Cupers; M Neumann; Hans A Kretzschmar; M Beyermann; D Schleuder; Holger Jahn; E Rüther; J Kornhuber; Willem ANNAERT; Bart De Strooper; Paul Saftig
Elevation of beta-amyloid peptide 2-42 in sporadic and familial Alzheimer's disease and its generation in PS1 knockout cells.
The Journal of biological chemistry 2001;276(46):42645-57.
2001: Manuela Neumann; Walter Schulz-Schaeffer; R A Crowther; M J Smith; Maria Grazia Spillantini; Michel Goedert; Hans A Kretzschmar
Pick's disease associated with the novel Tau gene mutation K369I.
Annals of neurology 2001;50(4):503-13.
2001: P A McBride; Walter Schulz-Schaeffer; M Donaldson; M Bruce; H Diringer; Hans A Kretzschmar; Michael Beekes
Early spread of scrapie from the gastrointestinal tract to the central nervous system involves autonomic fibers of the splanchnic and vagus nerves.
Journal of virology 2001;75(19):9320-7.
2001: B Schröder; B Franz; P Hempfling; M Selbert; T Jürgens; Hans A Kretzschmar; Monika Bodemer; Sigrid Poser; Inga Zerr
Polymorphisms within the prion-like protein gene (Prnd) and their implications in human prion diseases, Alzheimer's disease and other neurological disorders.
Human genetics 2001;109(3):319-25.
2001: Peter Ratzka; Andreas Schröter; Lukas Cepek; Karsten Henkel; Jens Wiltfang; Hans A Kretzschmar; Hilmar Prange; Sigrid Poser; Markus Otto
Unaltered apoptotic behaviour of mononuclear cells from patients with sporadic Creutzfeldt-Jakob disease.
Journal of neurology 2001;248(8):690-4.
2001: N Itoh; Hiroyuki Arai; Katsuya Urakami; K Ishiguro; H Ohno; Harald Hampel; Katharina Buerger; J Wiltfang; M Otto; Hans A Kretzschmar; H- J Moeller; M Imagawa; H Kohno; K Nakashima; Shigeki Kuzuhara; Hidetada Sasaki; K Imahori
Large-scale, multicenter study of cerebrospinal fluid tau protein phosphorylated at serine 199 for the antemortem diagnosis of Alzheimer's disease.
Annals of neurology 2001;50(2):150-6.
2001: Henriette J Tschampa; Manuela Neumann; Inga Zerr; Karsten Henkel; Andreas Schröter; Walter Schulz-Schaeffer; Bernhard J Steinhoff; Hans A Kretzschmar; Sigrid Poser
Patients with Alzheimer's disease and dementia with Lewy bodies mistaken for Creutzfeldt-Jakob disease.
Journal of neurology, neurosurgery, and psychiatry 2001;71(1):33-9.
2001: Michael L Kramer; Hartmut Kratzin; Bernhard Schmidt; A Römer; Otto Windl; S Liemann; Simone Hornemann; Hans A Kretzschmar
Prion protein binds copper within the physiological concentration range.
The Journal of biological chemistry 2001;276(20):16711-9.
2001: Manfred Oehmichen; Walter Schulz-Schaeffer; Hans A Kretzschmar; I Theuerkauf; I Gerling; Otto Windl; Christoph Meissner
Creutzfeldt-Jakob disease (CJD) in a case of suspected chronic heavy metal poisoning.
Journal of forensic sciences 2001;46(3):702-7.
2001: I Schneider; D Reverse; Ilse Dewachter; Laurence Ris; Nathalie Caluwaerts; Cuno Kuiperi; M Gilis; Hugo Geerts; Hans A Kretzschmar; Emile Godaux; Dieder Moechars; Fred Van Leuven; Jochen Herms
Mutant presenilins disturb neuronal calcium homeostasis in the brain of transgenic mice, decreasing the threshold for excitotoxicity and facilitating long-term potentiation.
The Journal of biological chemistry 2001;276(15):11539-44.
2001: Jochen Herms; Tobias Tings; S Dunker; Hans A Kretzschmar
Prion protein affects Ca2+-activated K+ currents in cerebellar purkinje cells.
Neurobiology of disease 2001;8(2):324-30.
2001: Harald Steiner; Tamas Revesz; M Neumann; H Romig; MG Grim; B Pesold; Hans A Kretzschmar; John Hardy; Janice L Holton; Ralf Baumeister; Henry Houlden; Christian Haass
A pathogenic presenilin-1 deletion causes abberrant Abeta 42 production in the absence of congophilic amyloid plaques.
The Journal of biological chemistry 2001;276(10):7233-9.
2001: M Papós; Arnulf Pekrun; Jochen Herms; Thomas M Behr; J Meller; Hans-Heino Rustenbeck; Hans A Kretzschmar; Wolfgang Becker
Somatostatin receptor scintigraphy in the management of cerebral malignant ectomesenchymoma: a case report.
Pediatric radiology 2001;31(3):169-72.
2001: Jan Dürig; A Giese; U Schmücker; Hans A Kretzschmar; Ulrich Dührsen
Decreased prion protein expression in human peripheral blood leucocytes from patients with paroxysmal nocturnal haemoglobinuria.
British journal of haematology 2001;112(3):658-62.
2001: Henriette J Tschampa; Walter Schulz-Schaeffer; J Wiltfang; Sigrid Poser; M Otto; Manuela Neumann; Hans A Kretzschmar
Decreased CSF amyloid beta42 and normal tau levels in dementia with Lewy bodies.
Neurology 2001;56(4):576.
2001: Martin Enders; E Fröhlich; Dieter Hassler; Hans A Kretzschmar
[BSE (bovine spongiform encephalopathy) and the new variant of Creutzfeldt-Jakob disease].
Deutsche medizinische Wochenschrift (1946) 2001;126(4):A55-6.
2001: Hans A Kretzschmar; T Tings; A Madlung; A Giese; J Herms
Prion protein as copper-binding protein at the synapse.
Methods in molecular medicine 2001;59():17-30.
2001: Christoph J G Lang; Josef G Heckmann; V Querner; Bernhard Neundörfer; Johannes Kornhuber; M Buchfelder; Hans A Kretzschmar
Disease latency in Creutzfeldt-Jakob disease via dural grafting: a case report.
European journal of epidemiology 2001;17(11):1013-4.
2001: Armin Giese; Hans A Kretzschmar
Prion-induced neuronal damage--the mechanisms of neuronal destruction in the subacute spongiform encephalopathies.
Current topics in microbiology and immunology 2001;253():203-17.
2001: Iris Augustin; S Korte; M Rickmann; Hans A Kretzschmar; Thomas C Südhof; Jochen Herms; Nils Brose
The cerebellum-specific Munc13 isoform Munc13-3 regulates cerebellar synaptic transmission and motor learning in mice.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2001;21(1):10-7.
2000: M Neumann; S Adler; O Schlüter; Elisabeth Kremmer; R Benecke; Hans A Kretzschmar
Alpha-synuclein accumulation in a case of neurodegeneration with brain iron accumulation type 1 (NBIA-1, formerly Hallervorden-Spatz syndrome) with widespread cortical and brainstem-type Lewy bodies.
Acta neuropathologica 2000;100(5):568-74.
2000: T Gasser; M Dichgans; K Jurkat-Rott; T Klockgether; Thomas Klopstock; Hans A Kretzschmar; F Lehmann-Horn; Heinz Reichmann; A Rolfs; T Sander; F Stögbauer
[Molecular diagnosis of hereditary neurologic diseases. Position paper].
Der Nervenarzt 2000;71(10):774-96.
2000: Francesco Scaravilli; Rebecca Cordery; Hans A Kretzschmar; P Gambetti; B Brink; V Fritz; J Temlett; C Kaplan; D Fish; Shu F An; W J Schulz-Schaeffer; Martin N Rossor
Sporadic fatal insomnia: a case study.
Annals of neurology 2000;48(4):665-8.
2000: Jochen Herms; S Korte; S Gall; I Schneider; S Dunker; Hans A Kretzschmar
Altered intracellular calcium homeostasis in cerebellar granule cells of prion protein-deficient mice.
Journal of neurochemistry 2000;75(4):1487-92.
2000: K Bürger; Harald Hampel; M Neumann; Hans-Jürgen Möller; Hans A Kretzschmar
[Your help is needed! Autopsy brings new knowledge regarding Alzheimer dementia].
MMW Fortschritte der Medizin 2000;142(39):40-1.
2000: Hans A Kretzschmar
[Interesting not only as differential Alzheimer dementia diagnosis. Bovine spongiform encephalopathy and other prion diseases].
MMW Fortschritte der Medizin 2000;142(39):34-8.
2000: Jochen Herms; I Neidt; B Lüscher; A Sommer; P Schürmann; T Schröder; M Bergmann; Bernd Wilken; S Probst-Cousin; P Hernáiz-Driever; J Behnke; Folker Hanefeld; T Pietsch; Hans A Kretzschmar
C-MYC expression in medulloblastoma and its prognostic value.
International journal of cancer. Journal international du cancer 2000;89(5):395-402.
2000: Hans A Kretzschmar; M Neumann
[Neuropathological diagnosis of neurodegenerative and dementia diseases].
Der Pathologe 2000;21(5):364-74.
2000: Inga Zerr; Walter Schulz-Schaeffer; Armin Giese; Monika Bodemer; Andreas Schröter; Karsten Henkel; Henriette J Tschampa; Otto Windl; A Pfahlberg; Bernhard J Steinhoff; Olaf Gefeller; Hans A Kretzschmar; Sigrid Poser
Current clinical diagnosis in Creutzfeldt-Jakob disease: identification of uncommon variants.
Annals of neurology 2000;48(3):323-9.
2000: Philipp J Kahle; Manuela Neumann; Laurence Ozmen; V Muller; Helmut Jacobsen; A Schindzielorz; Masayasu Okochi; U Leimer; H van Der Putten; A Probst; Elisabeth Kremmer; Hans A Kretzschmar; Christian Haass
Subcellular localization of wild-type and Parkinson's disease-associated mutant alpha -synuclein in human and transgenic mouse brain.
The Journal of neuroscience : the official journal of the Society for Neuroscience 2000;20(17):6365-73.
2000: Piero Parchi; Wenquan Zou; W Wang; P Brown; Sabina Capellari; Bernardino Ghetti; Nicolas Kopp; Walter Schulz-Schaeffer; Hans A Kretzschmar; M W Head; James W Ironside; Pierluigi Gambetti; Shu G Chen
Genetic influence on the structural variations of the abnormal prion protein.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(18):10168-72.
2000: Kefeng Qin; Dun-Sheng Yang; Ying Yang; M Azhar Chishti; L J Meng; Hans A Kretzschmar; Christopher M Yip; Paul E Fraser; David Westaway
Copper(II)-induced conformational changes and protease resistance in recombinant and cellular PrP. Effect of protein age and deamidation.
The Journal of biological chemistry 2000;275(25):19121-31.
2000: Jan Bieschke; Armin Giese; W Schulz-Schaeffer; I Zerr; S Poser; Manfred Eigen; Hans A Kretzschmar
Ultrasensitive detection of pathological prion protein aggregates by dual-color scanning for intensely fluorescent targets.
Proceedings of the National Academy of Sciences of the United States of America 2000;97(10):5468-73.
2000: Stefan Bleich; Stefan Kropp; Detlef Degner; Inga Zerr; Jürgen Pilz; Christoph H Gleiter; Markus Otto; Eckart Rüther; Hans A Kretzschmar; Jens Wiltfang; Johannes Kornhuber; Sigrid Poser
Creutzfeldt-Jakob disease and oxidative stress.
Acta neurologica Scandinavica 2000;101(5):332-4.
2000: Markus Otto; Hermann Esselmann; W Schulz-Shaeffer; Manuela Neumann; Andreas Schröter; Peter Ratzka; Lukas Cepek; Inga Zerr; Petra Steinacker; Otto Windl; Johannes Kornhuber; Hans A Kretzschmar; Sigrid Poser; Jens Wiltfang
Decreased beta-amyloid1-42 in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Neurology 2000;54(5):1099-102.
2000: Jan Dürig; A Giese; W Schulz-Schaeffer; C Rosenthal; U Schmücker; Jan Bieschke; Ulrich Dührsen; Hans A Kretzschmar
Differential constitutive and activation-dependent expression of prion protein in human peripheral blood leucocytes.
British journal of haematology 2000;108(3):488-95.
2000: K Post; D R Brown; Martin H Groschup; Hans A Kretzschmar; Detlev Riesner
Neurotoxicity but not infectivity of prion proteins can be induced reversibly in vitro.
Archives of virology. Supplementum 2000;(16):265-73.
2000: Hans A Kretzschmar; Tobias Tings; A Madlung; Armin Giese; Jochen Herms
Function of PrP(C) as a copper-binding protein at the synapse.
Archives of virology. Supplementum 2000;(16):239-49.
2000: Walter Schulz-Schaeffer; Rosmarie Fatzer; Marc Vandevelde; Hans A Kretzschmar
Detection of PrP(Sc) in subclinical BSE with the paraffin-embedded tissue (PET) blot.
Archives of virology. Supplementum 2000;(16):173-80.
2000: Armin Giese; Jan Bieschke; Manfred Eigen; Hans A Kretzschmar
Putting prions into focus: application of single molecule detection to the diagnosis of prion diseases.
Archives of virology. Supplementum 2000;(16):161-71.
2000: Sigrid Poser; Inga Zerr; A Schroeter; Markus Otto; Armin Giese; Bernhard J Steinhoff; Hans A Kretzschmar
Clinical and differential diagnosis of Creutzfeldt-Jakob disease.
Archives of virology. Supplementum 2000;(16):153-9.
2000: Walter Schulz-Schaeffer; S Tschöke; N Kranefuss; W Dröse; D Hause-Reitner; Armin Giese; M H Groschup; Hans A Kretzschmar
The paraffin-embedded tissue blot detects PrP(Sc) early in the incubation time in prion diseases.
The American journal of pathology 2000;156(1):51-6.
1999: A Harder; K Jendroska; F Kreuz; T Wirth; C Schafranka; N Karnatz; A Théallier-Janko; J Dreier; K Lohan; D Emmerich; J Cervós-Navarro; Otto Windl; Hans A Kretzschmar; Peter Nürnberg; R Witkowski
Novel twelve-generation kindred of fatal familial insomnia from germany representing the entire spectrum of disease expression.
American journal of medical genetics 1999;87(4):311-6.
1999: Jens Wiltfang; Markus Otto; Helen C Baxter; Monika Bodemer; Petra Steinacker; Erik Bahn; Inga Zerr; Johannes Kornhuber; Hans A Kretzschmar; Sigrid Poser; Eckart Rüther; Alastair Aitken
Isoform pattern of 14-3-3 proteins in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Journal of neurochemistry 1999;73(6):2485-90.
1999: Sigrid Poser; Brit Mollenhauer; A Kraubeta; Inga Zerr; Bernhard J Steinhoff; A Schroeter; M Finkenstaedt; Walter Schulz-Schaeffer; Hans A Kretzschmar; K Felgenhauer
How to improve the clinical diagnosis of Creutzfeldt-Jakob disease.
Brain : a journal of neurology 1999;122 ( Pt 12)():2345-51.
1999: KH Skworc; Otto Windl; Walter Schulz-Schaeffer; Armin Giese; J Bergk; A Nägele; Peter Vieregge; Inga Zerr; Sigrid Poser; Hans A Kretzschmar
Familial Creutzfeldt-Jakob disease with a novel 120-bp insertion in the prion protein gene.
Annals of neurology 1999;46(5):693-700.
1999: Alexander Bürkle; Hans A Kretzschmar; D R Brown
Poly(ADP-ribose) immunostaining to detect apoptosis induced by a neurotoxic fragment of prion protein.
The Histochemical journal 1999;31(11):711-6.
1999: I Samman; W J Schulz-Schaeffer; J C Wöhrle; A Sommer; Hans A Kretzschmar; Michael Hennerici
Clinical range and MRI in Creutzfeldt-Jakob disease with heterozygosity at codon 129 and prion protein type 2.
Journal of neurology, neurosurgery, and psychiatry 1999;67(5):678-81.
1999: Jochen Herms; Tobias Tings; S Gall; A Madlung; Armin Giese; Heike Siebert; P Schürmann; Otto Windl; Nils Brose; Hans A Kretzschmar
Evidence of presynaptic location and function of the prion protein.
The Journal of neuroscience : the official journal of the Society for Neuroscience 1999;19(20):8866-75.
1999: Otto Windl; Armin Giese; Walter Schulz-Schaeffer; Inga Zerr; KH Skworc; S Arendt; C Oberdieck; Monika Bodemer; Sigrid Poser; Hans A Kretzschmar
Molecular genetics of human prion diseases in Germany.
Human genetics 1999;105(3):244-52.
1999: Piero Parchi; A Giese; Sabina Capellari; P Brown; Walter Schulz-Schaeffer; Otto Windl; I Zerr; Herbert Budka; Nicolas Kopp; Pedro Piccardo; S Poser; A Rojiani; N Streichemberger; J Julien; Claude Vital; Bernardino Ghetti; Pierluigi Gambetti; Hans A Kretzschmar
Classification of sporadic Creutzfeldt-Jakob disease based on molecular and phenotypic analysis of 300 subjects.
Annals of neurology 1999;46(2):224-33.
1999: A Alperovitch; Inga Zerr; Maurizio Pocchiari; Eva Mitrova; Jesús de Pedro-Cuesta; I Hegyi; Steven Collins; Hans A Kretzschmar; C.M. Duijn; Robert G Will
Codon 129 prion protein genotype and sporadic Creutzfeldt-Jakob disease.
Lancet 1999;353(9165):1673-4.
1999: Jochen Herms; F D von Loewenich; J Behnke; Evagelos Markakis; Hans A Kretzschmar
c-myc oncogene family expression in glioblastoma and survival.
Surgical neurology 1999;51(5):536-42.
1999: Stefan Kropp; Inga Zerr; Walter Schulz-Schaeffer; C Riedemann; Monika Bodemer; C Laske; Hans A Kretzschmar; Sigrid Poser
Increase of neuron-specific enolase in patients with Creutzfeldt-Jakob disease.
Neuroscience letters 1999;261(1-2):124-6.
1999: Hans A Kretzschmar
Molecular pathogenesis of prion diseases.
European archives of psychiatry and clinical neuroscience 1999;249 Suppl 3():56-63.
1999: G Almer; Johannes A Hainfellner; Thomas Brücke; Kurt A Jellinger; Reinhold Kleinert; Guenther Bayer; O Windl; Hans A Kretzschmar; A Hill; K Sidle; J Collinge; Herbert Budka
Fatal familial insomnia: a new Austrian family.
Brain : a journal of neurology 1999;122 ( Pt 1)():5-16.
1999: Otto Windl; Holger Lorenz; C Behrens; A Römer; Hans A Kretzschmar
Construction and characterization of murine neuroblastoma cell clones allowing inducible and high expression of the prion protein.
The Journal of general virology 1999;80 ( Pt 1)():15-21.
1999: Stefan Kropp; Walter Schulz-Schaeffer; M Finkenstaedt; C Riedemann; Otto Windl; Bernhard J Steinhoff; Inga Zerr; Hans A Kretzschmar; Sigrid Poser
The Heidenhain variant of Creutzfeldt-Jakob disease.
Archives of neurology 1999;56(1):55-61.
1998: Inga Zerr; Armin Giese; Otto Windl; Stefan Kropp; Walter Schulz-Schaeffer; C Riedemann; KH Skworc; Monika Bodemer; Hans A Kretzschmar; Sigrid Poser
Phenotypic variability in fatal familial insomnia (D178N-129M) genotype.
Neurology 1998;51(5):1398-405.
1998: B Behring; Wolfgang Beuche; Hans A Kretzschmar
Progressive dementia with parkinsonism in corticobasal and brainstem degeneration with neuronal inclusions.
Neurology 1998;51(1):285-8.
1998: Hans A Kretzschmar; Armin Giese; Inga Zerr; Otto Windl; Walter Schulz-Schaeffer; KH Skworc; Sigrid Poser
The German FFI cases.
Brain pathology (Zurich, Switzerland) 1998;8(3):559-61.
1998: Armin Giese; David Brown; M H Groschup; C Feldmann; I Haist; Hans A Kretzschmar
Role of microglia in neuronal cell death in prion disease.
Brain pathology (Zurich, Switzerland) 1998;8(3):449-57.
1998: David Brown; A Besinger; Jochen Herms; Hans A Kretzschmar
Microglial expression of the prion protein.
Neuroreport 1998;9(7):1425-9.
1998: D R Brown; B Schmidt; Hans A Kretzschmar
Prion protein fragment interacts with PrP-deficient cells.
Journal of neuroscience research 1998;52(3):260-7.
1998: D R Brown; B Schmidt; Hans A Kretzschmar
A prion protein fragment primes type 1 astrocytes to proliferation signals from microglia.
Neurobiology of disease 1998;4(6):410-22.
1998: D R Brown; B Schmidt; Hans A Kretzschmar
Effects of copper on survival of prion protein knockout neurons and glia.
Journal of neurochemistry 1998;70(4):1686-93.
1998: Markus Otto; Jens Wiltfang; E Schütz; Inga Zerr; A Otto; A Pfahlberg; Olaf Gefeller; M Uhr; Armin Giese; T Weber; Hans A Kretzschmar; Sigrid Poser
Diagnosis of Creutzfeldt-Jakob disease by measurement of S100 protein in serum: prospective case-control study.
BMJ (Clinical research ed.) 1998;316(7131):577-82.
1998: D R Brown; Hans A Kretzschmar
The glio-toxic mechanism of alpha-aminoadipic acid on cultured astrocytes.
Journal of neurocytology 1998;27(2):109-18.
1998: Hans A Kretzschmar
[Transmissible spongiform encephalopathies (prion diseases)--molecular principles and in vitro models].
Wiener medizinische Wochenschrift (1946) 1998;148(4):67-73.
1998: D R Brown; B Schmidt; Martin H Groschup; Hans A Kretzschmar
Prion protein expression in muscle cells and toxicity of a prion protein fragment.
European journal of cell biology 1998;75(1):29-37.
1998: Inga Zerr; Monika Bodemer; Olaf Gefeller; Markus Otto; Sigrid Poser; Jens Wiltfang; Otto Windl; Hans A Kretzschmar; T Weber
Detection of 14-3-3 protein in the cerebrospinal fluid supports the diagnosis of Creutzfeldt-Jakob disease.
Annals of neurology 1998;43(1):32-40.
1997: David Brown; K Qin; Jochen Herms; A Madlung; J Manson; R Strome; Paul E Fraser; T Kruck; A von Bohlen; Walter Schulz-Schaeffer; Armin Giese; David Westaway; Hans A Kretzschmar
The cellular prion protein binds copper in vivo.
Nature 1997;390(6661):684-7.
1997: D R Brown; B Schmidt; Hans A Kretzschmar
Effects of oxidative stress on prion protein expression in PC12 cells.
International journal of developmental neuroscience : the official journal of the International Society for Developmental Neuroscience 1997;15(8):961-72.
1997: Carsten Korth; Beat Stierli; Peter Streit; Markus Moser; Olivier Schaller; R Fischer; W Schulz-Schaeffer; Hans A Kretzschmar; Alex J Raeber; U Braun; Felix Ehrensperger; Simone Hornemann; Rudi Glockshuber; Roland Riek; M Billeter; Kurt Wüthrich; Bruno Oesch
Prion (PrPSc)-specific epitope defined by a monoclonal antibody.
Nature 1997;390(6655):74-7.
1997: Jochen Herms; J Behnke; M Bergmann; HJ Christen; R Kolb; M Wilkening; Evagelos Markakis; Folker Hanefeld; Hans A Kretzschmar
Potential prognostic value of C-erbB-2 expression in medulloblastomas in very young children.
Journal of pediatric hematology/oncology 1997;19(6):510-5.
1997: S Weiss; Daniela Proske; M Neumann; M H Groschup; Hans A Kretzschmar; Michael Famulok; Ernst-L Winnacker
RNA aptamers specifically interact with the prion protein PrP.
Journal of virology 1997;71(11):8790-7.
1997: Jochen Herms; A Madlung; David Brown; Hans A Kretzschmar
Increase of intracellular free Ca2+ in microglia activated by prion protein fragment.
Glia 1997;21(2):253-7.
1997: Sigrid Poser; Inga Zerr; Walter Schulz-Schaeffer; Hans A Kretzschmar; K Felgenhauer
[The Creutzfeld-Jakob disease. A sphinx of current neurobiology].
Deutsche medizinische Wochenschrift (1946) 1997;122(37):1099-105.
1997: Markus Otto; H Stein; A Szudra; Inga Zerr; Monika Bodemer; Olaf Gefeller; Sigrid Poser; Hans A Kretzschmar; Michael Mäder; T Weber
S-100 protein concentration in the cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Journal of neurology 1997;244(9):566-70.
1997: M Schwaninger; R Winter; W Hacke; R von Kummer; C Sommer; Marika Kiessling; W J Schulz-Schaeffer; Hans A Kretzschmar
Magnetic resonance imaging in Creutzfeldt-Jakob disease: evidence of focal involvement of the cortex.
Journal of neurology, neurosurgery, and psychiatry 1997;63(3):408-9.
1997: D R Brown; Walter Schulz-Schaeffer; B Schmidt; Hans A Kretzschmar
Prion protein-deficient cells show altered response to oxidative stress due to decreased SOD-1 activity.
Experimental neurology 1997;146(1):104-12.
1997: David Brown; Hans A Kretzschmar
Microglia and prion disease: a review.
Histology and histopathology 1997;12(3):883-92.
1997: T Weber; C Trebst; Stephan Frye; Paola Cinque; L Vago; C J M Sindic; W J Schulz-Schaeffer; Hans A Kretzschmar; W Enzensberger; Gerhard Hunsmann; Wolfgang Lüke
Analysis of the systemic and intrathecal humoral immune response in progressive multifocal leukoencephalopathy.
The Journal of infectious diseases 1997;176(1):250-4.
1997: David Brown; Jochen Herms; B Schmidt; Hans A Kretzschmar
PrP and beta-amyloid fragments activate different neurotoxic mechanisms in cultured mouse cells.
The European journal of neuroscience 1997;9(6):1162-9.
1997: K Schallock; Walter Schulz-Schaeffer; A Giese; Hans A Kretzschmar
Postmortem delay and temperature conditions affect the in situ end-labeling (ISEL) assay in brain tissue of mice.
Clinical neuropathology 1997;16(3):133-6.
1997: Markus Otto; Jens Wiltfang; Hayrettin Tumani; Inga Zerr; M Lantsch; Johannes Kornhuber; T Weber; Hans A Kretzschmar; Sigrid Poser
Elevated levels of tau-protein in cerebrospinal fluid of patients with Creutzfeldt-Jakob disease.
Neuroscience letters 1997;225(3):210-2.
1997: Piero Parchi; Sabina Capellari; S G Chen; Robert B Petersen; P Gambetti; Nicolas Kopp; P Brown; Tetsuyuki Kitamoto; Jun Tateishi; A Giese; Hans A Kretzschmar
Typing prion isoforms.
Nature 1997;386(6622):232-4.
1997: Hans A Kretzschmar; Armin Giese; David Brown; Jochen Herms; B Keller; B Schmidt; Martin H Groschup
Cell death in prion disease.
Journal of neural transmission. Supplementum 1997;50():191-210.
1996: Juergen Kohlhase; Reinhard Schuh; G Dowe; Ronald P Kühnlein; Herbert Jäckle; B Schroeder; Walter Schulz-Schaeffer; Hans A Kretzschmar; A Köhler; U Müller; M Raab-Vetter; E Burkhardt; Wolfgang Engel; R Stick
Isolation, characterization, and organ-specific expression of two novel human zinc finger genes related to the Drosophila gene spalt.
Genomics 1996;38(3):291-8.
1996: J Weis; Hans A Kretzschmar; Otto Windl; K Podoll; M Schwarz
Fatal spongiform encephalopathy in a patient who had handled animal feed.
Lancet 1996;348(9036):1240.
1996: Jun Tateishi; Tetsuyuki Kitamoto; Hans A Kretzschmar; P Mehraein
Immunhistological evaluation of Creutzfeldt-Jakob disease with reference to the type PrPres deposition.
Clinical neuropathology 1996;15(6):358-60.
1996: Walter Schulz-Schaeffer; Armin Giese; Otto Windl; Hans A Kretzschmar
Polymorphism at codon 129 of the prion protein gene determines cerebellar pathology in Creutzfeldt-Jakob disease.
Clinical neuropathology 1996;15(6):353-7.
1996: W Brück; N Sommermeier; M Bergmann; Uwe K Zettl; H H Goebel; Hans A Kretzschmar; H Lassmann
Macrophages in multiple sclerosis.
Immunobiology 1996;195(4-5):588-600.
1996: Inga Zerr; Monika Bodemer; Markus Otto; Sigrid Poser; Otto Windl; Hans A Kretzschmar; Olaf Gefeller; T Weber
Diagnosis of Creutzfeldt-Jakob disease by two-dimensional gel electrophoresis of cerebrospinal fluid.
Lancet 1996;348(9031):846-9.
1996: D R Brown; B Schmidt; Hans A Kretzschmar
A neurotoxic prion protein fragment enhances proliferation of microglia but not astrocytes in culture.
Glia 1996;18(1):59-67.
1996: Hans A Kretzschmar; J W Ironside; S J DeArmond; J Tateishi
Diagnostic criteria for sporadic Creutzfeldt-Jakob disease.
Archives of neurology 1996;53(9):913-20.
1996: M Bergmann; Klaus Kuchelmeister; Kurt W Schmid; Hans A Kretzschmar; R Schröder
Different variants of frontotemporal dementia: a neuropathological and immunohistochemical study.
Acta neuropathologica 1996;92(2):170-9.
1996: Hans A Kretzschmar
[Bovine spongiform encephalopathy--a challenge for modern medicine].
Der Internist 1996;37(6):658-60.
1996: David Brown; B Schmidt; Hans A Kretzschmar
Role of microglia and host prion protein in neurotoxicity of a prion protein fragment.
Nature 1996;380(6572):345-7.
1996: Herbert Budka; A Aguzzi; P Brown; J M Brucher; O Bugiani; John Collinge; H Diringer; F Gullotta; M Haltia; JEAN-JACQUES HAUW; J W Ironside; Hans A Kretzschmar; P L Lantos; Carlo Masullo; Maurizio Pocchiari; W Schlote; J Tateishi; Robert G Will
[Consensus report: tissue handling in suspected Creutzfeldt-Jakob disease and other spongiform encephalopathies (prion diseases) in the human. European Union Biomed-1 Concerted Action].
Der Pathologe 1996;17(2):171-5.
1996: Y Brück; W Brück; Hans A Kretzschmar; H Lassmann
Evidence for neuronal apoptosis in pontosubicular neuron necrosis.
Neuropathology and applied neurobiology 1996;22(1):23-9.
1996: Bernhard J Steinhoff; S Räcker; Gregor Herrendorf; Sigrid Poser; S Grosche; Inga Zerr; Hans A Kretzschmar; T Weber
Accuracy and reliability of periodic sharp wave complexes in Creutzfeldt-Jakob disease.
Archives of neurology 1996;53(2):162-6.
1996: B Behring; W Brück; H H Goebel; J Behnke; Arnulf Pekrun; H J Christen; Hans A Kretzschmar
Immunohistochemistry of primary central nervous system malignant rhabdoid tumors: report of five cases and review of the literature.
Acta neuropathologica 1996;91(6):578-86.
1995: S Krasemann; Inga Zerr; T Weber; Sigrid Poser; Hans A Kretzschmar; Gerhard Hunsmann; Walter Bodemer
Prion disease associated with a novel nine octapeptide repeat insertion in the PRNP gene.
Brain research. Molecular brain research 1995;34(1):173-6.
1995: G Obermaier; Hans A Kretzschmar; A Hafner; D Heubeck; E Dahme
Spongiform central nervous system myelinopathy in African dwarf goats.
Journal of comparative pathology 1995;113(4):357-72.
1995: W Brück; P Porada; Sigrid Poser; Peter Rieckmann; Folker Hanefeld; Hans A Kretzschmar; H Lassmann
Monocyte/macrophage differentiation in early multiple sclerosis lesions.
Annals of neurology 1995;38(5):788-96.
1995: Armin Giese; Martin H Groschup; B Hess; Hans A Kretzschmar
Neuronal cell death in scrapie-infected mice is due to apoptosis.
Brain pathology (Zurich, Switzerland) 1995;5(3):213-21.
1995: Inga Zerr; Monika Bodemer; S Räcker; S Grosche; Sigrid Poser; Hans A Kretzschmar; T Weber
Cerebrospinal fluid concentration of neuron-specific enolase in diagnosis of Creutzfeldt-Jakob disease.
Lancet 1995;345(8965):1609-10.
1995: David Brown; Hans A Kretzschmar
Topographical reinnervation of the toad glutaeus muscle by axons of only one spinal nerve.
Neuroreport 1995;6(7):989-93.
1995: K H Frenzel; Norbert Müller; D Heidmann; Harald Hampel; Hans A Kretzschmar; Randolph Penning; Manfred Ackenheil
Expression of T cell receptor gamma delta antigens in human brain tissue.
Neuroimmunomodulation 1995;2(2):115-20.
1995: Hans A Kretzschmar; M Neumann; D Stavrou
Codon 178 mutation of the human prion protein gene in a German family (Backer family): sequencing data from 72-year-old celloidin-embedded brain tissue.
Acta neuropathologica 1995;89(1):96-8.
1994: T Bogumil; Wolfgang Beuche; C Schindler; W Schachenmayr; Hans A Kretzschmar
[Creutzfeldt-Jakob disease. Report of a case with an unusually long course and immunohistochemical localization of the prion protein and overview of current information].
Der Nervenarzt 1994;65(12):865-73.
1994: U Schumacher; E Adam; Hans A Kretzschmar; U Pfüller
Binding patterns of mistletoe lectins I, II and III to microglia and Alzheimer plaque glycoproteins in human brains.
Acta histochemica 1994;96(4):399-403.
1994: David Brown; Jochen Herms; Hans A Kretzschmar
Mouse cortical cells lacking cellular PrP survive in culture with a neurotoxic PrP fragment.
Neuroreport 1994;5(16):2057-60.
1994: Oskar-Rüger Kaaden; Uwe Truyen; M H Groschup; A Uysal; E Kaiser; Hans A Kretzschmar; T Bogumil; J Pohlenz; H Diringer; P Steinhagen
Bovine spongiform encephalopathy in Germany.
Zentralblatt für Veterinärmedizin. Reihe B. Journal of veterinary medicine. Series B 1994;41(4):294-304.
1994: S Treiber-Held; H Budjarjo-Welim; D Reimann; J Richter; Hans A Kretzschmar; Folker Hanefeld
Giant axonal neuropathy: a generalized disorder of intermediate filaments with longitudinal grooves in the hair.
Neuropediatrics 1994;25(2):89-93.
1994: T Weber; R W Turner; Stephan Frye; Wolfgang Lüke; Hans A Kretzschmar; W Lüer; Gerhard Hunsmann
Progressive multifocal leukoencephalopathy diagnosed by amplification of JC virus-specific DNA from cerebrospinal fluid.
AIDS (London, England) 1994;8(1):49-57.
1994: U Schumacher; Hans A Kretzschmar; U Pfüller
Staining of cerebral amyloid plaque glycoproteins in patients with Alzheimer's disease with the microglia-specific lectin from mistletoe.
Acta neuropathologica 1994;87(4):422-4.
1993: A Thiel; M E Pilichowska; B Hemmerlein; H J Kunert; I Lange; Hans A Kretzschmar; E Rüther
[Dementia and psychotic symptoms in amyotrophic lateral sclerosis].
Der Nervenarzt 1993;64(9):618-22.
1993: E Patsouris; Hans A Kretzschmar; Dimitrios Stavrou; Parviz Mehraein
Cellular composition and distribution of gliomesenchymal nodules in the CNS of AIDS patients.
Clinical neuropathology 1993;12(3):130-7.
1993: T Weber; Hayrettin Tumani; B Holdorff; J Collinge; M Palmer; Hans A Kretzschmar; K Felgenhauer
Transmission of Creutzfeldt-Jakob disease by handling of dura mater.
Lancet 1993;341(8837):123-4.
1993: Hans A Kretzschmar
Neuropathology of human prion diseases (spongiform encephalopathies).
Developments in biological standardization 1993;80():71-90.
1993: Hans A Kretzschmar
Human prion diseases (spongiform encephalopathies).
Archives of virology. Supplementum 1993;7():261-93.
1992: Jean-Marc Gabriel; Bruno Oesch; Hans A Kretzschmar; Michael Scott; Stanley B Prusiner
Molecular cloning of a candidate chicken prion protein.
Proceedings of the National Academy of Sciences of the United States of America 1992;89(19):9097-101.
1992: Hans A Kretzschmar; M Neumann; Gert Riethmüller; Stanley B Prusiner
Molecular cloning of a mink prion protein gene.
The Journal of general virology 1992;73 ( Pt 10)():2757-61.
1992: U Schumacher; Hans A Kretzschmar; S Brooks; A J C Leathem
Helix pomatia lectin binding pattern of brain metastases originating from breast cancers.
Pathology, research and practice 1992;188(3):284-6.
1992: Hans A Kretzschmar; Peter Kufer; Gert Riethmüller; S DeArmond; Stanley B Prusiner; D Schiffer
Prion protein mutation at codon 102 in an Italian family with Gerstmann-Sträussler-Scheinker syndrome.
Neurology 1992;42(4):809-10.
1991: K Jendroska; Frederick P Heinzel; M Torchia; L Stowring; Hans A Kretzschmar; Alexander A Kon; A Stern; Stanley B Prusiner; Stephen J DeArmond
Proteinase-resistant prion protein accumulation in Syrian hamster brain correlates with regional pathology and scrapie infectivity.
Neurology 1991;41(9):1482-90.
1991: Hans A Kretzschmar; G Honold; F Seitelberger; M Feucht; P Wessely; P Mehraein; Herbert Budka
Prion protein mutation in family first reported by Gerstmann, Sträussler, and Scheinker.
Lancet 1991;337(8750):1160.
1991: U Schumacher; Hans A Kretzschmar; J Tateishi
Carbohydrate histochemistry of amyloid plaques in Gerstmann-Sträussler syndrome.
European journal of basic and applied histochemistry 1991;35(4):331-40.
1991: Hans A Kretzschmar; T Kitamoto; J Doerr-Schott; Parviz Mehraein; J Tateishi
Diffuse deposition of immunohistochemically labeled prion protein in the granular layer of the cerebellum in a patient with Creutzfeldt-Jakob disease.
Acta neuropathologica 1991;82(6):536-40.
1990: Hans A Kretzschmar; H Wagner; G Hübner; Adrian Danek; T N Witt; Parviz Mehraein
Aneurysms and vacuolar degeneration of cerebral arteries in late-onset acid maltase deficiency.
Journal of the neurological sciences 1990;98(2-3):169-83.
1990: H Bertalanffy; Hans A Kretzschmar; Joachim M Gilsbach; D Ott; M Mohadjer
Large colloid cyst in lateral ventricle simulating brain tumour. Case report.
Acta neurochirurgica 1990;104(3-4):151-5.
1990: Hans A Kretzschmar; H R Eggert
Mesenchymal chondrosarcoma of the craniocervical junction.
Clinical neurology and neurosurgery 1990;92(4):343-7.
1989: Dimitrios Stavrou; Karl Bise; J Groeneveld; U Stocker; Hans A Kretzschmar; E Keiditsch; Parviz Mehraein
Antigenic heterogeneity of human brain tumors defined by monoclonal antibodies.
Anticancer research 1989;9(6):1489-96.
1989: Hans A Kretzschmar; H R Eggert; U Beck; R Fürmaier
Intracranial chondroma. Case report.
Surgical neurology 1989;32(2):121-5.
1987: Hans A Kretzschmar; S J DeArmond; Thomas K Koch; M S Patel; Christopher Newth; K A Schmidt; Seymour Packman
Pyruvate dehydrogenase complex deficiency as a cause of subacute necrotizing encephalopathy (Leigh disease).
Pediatrics 1987;79(3):370-3.
1987: Hans A Kretzschmar; B O Berg; R L Davis
Giant axonal neuropathy. A neuropathological study.
Acta neuropathologica 1987;73(2):138-44.
1986: S J DeArmond; Y L Lee; Hans A Kretzschmar; L F Eng
Turnover of glial filaments in mouse spinal cord.
Journal of neurochemistry 1986;47(6):1749-53.
1986: Hans A Kretzschmar; L E Stowring; D Westaway; W H Stubblebine; Stanley B Prusiner; S J Dearmond
Molecular cloning of a human prion protein cDNA.
DNA (Mary Ann Liebert, Inc.) 1986;5(4):315-24.
1986: U Dickmann; G Ritter; Hans A Kretzschmar
[Pemphigoid and cerebral infarct. Syntropy of 2 diseases? Case report].
Der Nervenarzt 1986;57(5):309-10.
1986: Hans A Kretzschmar; Stanley B Prusiner; L E Stowring; Stephen J DeArmond
Scrapie prion proteins are synthesized in neurons.
The American journal of pathology 1986;122(1):1-5.
1985: Hans A Kretzschmar; S J DeArmond; L S Forno
Measurement of GFAP in hepatic encephalopathy by ELISA and transblots.
Journal of neuropathology and experimental neurology 1985;44(5):459-71.
1985: D F Sobel; E Baker; B Anderson; Hans A Kretzschmar
Cerebral amyloid angiopathy associated with massive intracerebral hemorrhage.
Neuroradiology 1985;27(4):318-21.
1980: Hans A Kretzschmar; F Kirchner; K Takano
Relations between the effect of tetanus toxin on the neuromuscular transmission and histological functional properties of various muscles of the rat.
Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale 1980;38(2):181-7.