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Ron Kriz

Research Profile

Genes & Molecular Sequences

Amino Acid Sequences

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Xiaotian Zhong; J Christian Baber; Aaron D'Antona; Joel Desharnais; Lori Fitz; Tao He; Elizabeth Kieras; Ron Kriz; Laura Lin; Deborah Luxenberg; William S Somers; Eric Sousa; Mark Stahl; Lauren Wood; Jill F Wright
Pyroglutamate and O-linked glycan determine functional production of anti-IL17A and anti-IL22 peptide-antibody bispecific genetic fusions.
Xiaotian Zhong; Martin Allen; Cecilia Cooley; Z Sean Juo; Ravi Kumar; Lidia Mosyak; Ella Presman; Nicole Resendes; Nilufer Seth; William S Somers; Mark Stahl; Ron Kriz
Engineering novel Lec1 glycosylation mutants in CHO-DUKX cells: molecular insights and effector modulation of N-acetylglucosaminyltransferase I.
Xiaotian Zhong; Jennifer Pocas; Yan Liu; Paul W Wu; Lidia Mosyak; Will Somers; Ron Kriz
Swift residue-screening identifies key N-glycosylated asparagines sufficient for surface expression of neuroglycoprotein Lingo-1.

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All Publications

2013: Xiaotian Zhong; J Christian Baber; Aaron D'Antona; Joel Desharnais; Lori Fitz; Tao He; Elizabeth Kieras; Ron Kriz; Laura Lin; Deborah Luxenberg; William S Somers; Eric Sousa; Mark Stahl; Lauren Wood; Jill F Wright
Pyroglutamate and O-linked glycan determine functional production of anti-IL17A and anti-IL22 peptide-antibody bispecific genetic fusions.
The Journal of biological chemistry 2013;288(2):1409-19.
2012: Xiaotian Zhong; Martin Allen; Cecilia Cooley; Z Sean Juo; Ravi Kumar; Lidia Mosyak; Ella Presman; Nicole Resendes; Nilufer Seth; William S Somers; Mark Stahl; Ron Kriz
Engineering novel Lec1 glycosylation mutants in CHO-DUKX cells: molecular insights and effector modulation of N-acetylglucosaminyltransferase I.
Biotechnology and bioengineering 2012;109(7):1723-34.
2009: Xiaotian Zhong; Jennifer Pocas; Yan Liu; Paul W Wu; Lidia Mosyak; Will Somers; Ron Kriz
Swift residue-screening identifies key N-glycosylated asparagines sufficient for surface expression of neuroglycoprotein Lingo-1.
FEBS letters 2009;583(6):1034-8.
2009: Andrea M Olland; James Strand; Eleonora Presman; Robert Czerwinski; Diane Joseph-McCarthy; Rustem Krykbaev; Gerhard Schlingmann; Rajiv Chopra; Laura Lin; Margaret Fleming; Ron Kriz; Mark Stahl; William Somers; Lori Fitz; Lidia Mosyak
Triad of polar residues implicated in pH specificity of acidic mammalian chitinase.
Protein science : a publication of the Protein Society 2009;18(3):569-78.
2008: Xiaotian Zhong; Madhavan Buddha; Guido Guidotti; Ron Kriz; Will Somers; Lidia Mosyak
Expression, purification and crystallization of the ecto-enzymatic domain of rat E-NTPDase1 CD39.
Acta crystallographica. Section F, Structural biology and crystallization communications 2008;64(Pt 11):1063-5.
2008: Lidia Mosyak; Katy E Georgiadis; Tania Shane; Kristine Svenson; Tracy Hebert; Thomas McDonagh; Stewart Mackie; Stephane Olland; Laura Lin; Xiaotian Zhong; Ron Kriz; Erica L Reifenberg; Lisa A Collins-Racie; Chris Corcoran; Bethany Freeman; Richard Zollner; Tod Marvell; Matthew Vera; Phaik-Eng Sum; Edward R LaVallie; Mark L Stahl; William Somers
Crystal structures of the two major aggrecan degrading enzymes, ADAMTS4 and ADAMTS5.
Protein science : a publication of the Protein Society 2008;17(1):16-21.
2007: Xiaotian Zhong; Thamara Desilva; Laura Lin; Peter V N Bodine; Ramesh A Bhat; Eleonora Presman; Jennifer Pocas; Mark L Stahl; Ron Kriz
Regulation of secreted Frizzled-related protein-1 by heparin.
The Journal of biological chemistry 2007;282(28):20523-33.
2006: Lidia Mosyak; Andrew Wood; Brian Dwyer; Madhavan Buddha; Mark Johnson; Ann Aulabaugh; Xiaotian Zhong; Eleonora Presman; Susan Benard; Kerry Kelleher; James Wilhelm; Mark L Stahl; Ron Kriz; Ying Gao; Zixuan Cao; Huai-Ping Ling; Menelas Pangalos; Frank S Walsh; William S Somers
The structure of the Lingo-1 ectodomain, a module implicated in central nervous system repair inhibition.
The Journal of biological chemistry 2006;281(47):36378-90.
2006: Guixian Jin; Ann Aulabaugh; Jennifer Pocas; Hao Liu; Ron Kriz; Deepak Sampath
Development and comparison of nonradioactive in vitro kinase assays for NIMA-related kinase 2.
Analytical biochemistry 2006;358(1):59-69.
2006: Kristie Bridges; Rajiv Chopra; Laura Lin; Kristine Svenson; Amy Tam; Guixian Jin; Rebecca Cowling; Frank Lovering; Tatos N Akopian; Elizabeth DiBlasio-Smith; Bethany Annis-Freeman; Tod H Marvell; Edward R LaVallie; Richard Zollner; Jonathan Bard; William S Somers; Mark L Stahl; Ron Kriz
A novel approach to identifying beta-secretase inhibitors: bis-statine peptide mimetics discovered using structure and spot synthesis.
Peptides 2006;27(7):1877-85.
2006: Xiaoke Yang; Rita Capotosto; Elizabeth DiBlasio; Zhixiang Hu; Ron Kriz; Maria Lorenzo; Karl Malakian; Scott Wolfrom; James Wilhelm; Stanley Wolf
A homogeneous time-resolved fluorescence resonance energy transfer assay for IL-13/IL-13Ralpha1 interaction.
Analytical biochemistry 2006;351(1):158-60.
2005: Robert Czerwinski; Ann Aulabaugh; Rita M Greco; Stephane Olland; Karl Malakian; Scott Wolfrom; Laura Lin; Ron Kriz; Mark L Stahl; Ying Huang; Lin Liu; Divya Chaudhary
Characterization of protein kinase C theta activation loop autophosphorylation and the kinase domain catalytic mechanism.
Biochemistry 2005;44(28):9563-73.
2005: Xiaotian Zhong; Ron Kriz; Ravindra Kumar; Guido Guidotti
Distinctive roles of endoplasmic reticulum and golgi glycosylation in functional surface expression of mammalian E-NTPDase1, CD39.
Biochimica et biophysica acta 2005;1723(1-3):143-50.
2004: Xiaotian Zhong; Ron Kriz; Jasbir Seehra; Ravindra Kumar
N-linked glycosylation of platelet P2Y12 ADP receptor is essential for signal transduction but not for ligand binding or cell surface expression.
FEBS letters 2004;562(1-3):111-7.
2003: Cynthia Hess Kenny; Weidong Ding; Kerry Kelleher; Susan Benard; Elizabeth G Dushin; Alan G Sutherland; Lidia Mosyak; Ron Kriz; George Ellestad
Development of a fluorescence polarization assay to screen for inhibitors of the FtsZ/ZipA interaction.
Analytical biochemistry 2003;323(2):224-33.
2003: Kathryn W Underwood; Kevin D Parris; Elizabeth Federico; Lidia Mosyak; Robert Czerwinski; Tania Shane; Meggin Taylor; Kristine Svenson; Yan Liu; Chu-Lai Hsiao; Scott Wolfrom; Michelle Maguire; Karl Malakian; Jean-Baptiste Telliez; Lih-Ling Lin; Ron Kriz; Jasbir Seehra; William S Somers; Mark L Stahl
Catalytically active MAP KAP kinase 2 structures in complex with staurosporine and ADP reveal differences with the autoinhibited enzyme.
Structure (London, England : 1993) 2003;11(6):627-36.
1999: C Song; X J Chang; K M Bean; M S Proia; J L Knopf; Ron Kriz
Molecular characterization of cytosolic phospholipase A2-beta.
The Journal of biological chemistry 1999;274(24):17063-7.
1999: Kenneth A Jacobs; Lisa A Collins-Racie; M Colbert; M Duckett; C Evans; M Golden-Fleet; Kerry Kelleher; Ron Kriz; E R La Vallie; D Merberg; Vikki Spaulding; J Stover; M J Williamson; John McCoy
A genetic selection for isolating cDNA clones that encode signal peptides.
Methods in enzymology 1999;303():468-79.
1998: Kathryn W Underwood; C Song; Ron Kriz; X J Chang; J L Knopf; Lih-Ling Lin
A novel calcium-independent phospholipase A2, cPLA2-gamma, that is prenylated and contains homology to cPLA2.
The Journal of biological chemistry 1998;273(34):21926-32.
1998: F X Sullivan; R Kumar; Ron Kriz; Mark L Stahl; GY Xu; J Rouse; X J Chang; A Boodhoo; B Potvin; DA Cumming
Molecular cloning of human GDP-mannose 4,6-dehydratase and reconstitution of GDP-fucose biosynthesis in vitro.
The Journal of biological chemistry 1998;273(14):8193-202.
1997: Kenneth A Jacobs; Lisa A Collins-Racie; M Colbert; M Duckett; M Golden-Fleet; Kerry Kelleher; Ron Kriz; Edward R LaVallie; D Merberg; Vikki Spaulding; J Stover; M J Williamson; John McCoy
A genetic selection for isolating cDNAs encoding secreted proteins.
Gene 1997;198(1-2):289-96.
1997: J Tang; Ron Kriz; N Wolfman; M Shaffer; Jasbir Seehra; S S Jones
A novel cytosolic calcium-independent phospholipase A2 contains eight ankyrin motifs.
The Journal of biological chemistry 1997;272(13):8567-75.
1994: E A Nalefski; L A Sultzman; D M Martin; Ron Kriz; P S Towler; J L Knopf; J D Clark
Delineation of two functionally distinct domains of cytosolic phospholipase A2, a regulatory Ca(2+)-dependent lipid-binding domain and a Ca(2+)-independent catalytic domain.
The Journal of biological chemistry 1994;269(27):18239-49.
1994: M R Bowman; M A Crimmins; J Yetz-Aldape; Ron Kriz; K Kelleher; S Herrmann
The cloning of CD70 and its identification as the ligand for CD27.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(4):1756-61.
1993: HF Finnerty; Kerry Kelleher; G E Morris; K Bean; D M Merberg; Ron Kriz; J C Morris; H Sookdeo; KJ Turner; Clive R Wood
Molecular cloning of murine FLT and FLT4.
Oncogene 1993;8(8):2293-8.
1992: S R Paul; D Merberg; HF Finnerty; G E Morris; J C Morris; S S Jones; Ron Kriz; KJ Turner; Clive R Wood
Molecular cloning of the cDNA encoding a receptor tyrosine kinase-related molecule with a catalytic region homologous to c-met.
International journal of cell cloning 1992;10(5):309-14.
1992: D Park; D Y Jhon; Ron Kriz; J Knopf; Sue Goo Rhee
Cloning, sequencing, expression, and Gq-independent activation of phospholipase C-beta 2.
The Journal of biological chemistry 1992;267(23):16048-55.
1991: A J Dorner; F Bonneville; Ron Kriz; Kerry Kelleher; K Bean; Randal J Kaufman
Molecular cloning and characterization of a complete Chinese hamster provirus related to intracisternal A particle genomes.
Journal of virology 1991;65(9):4713-9.
1991: J D Clark; Lih-Ling Lin; Ron Kriz; C S Ramesha; L A Sultzman; A Y Lin; N Milona; J L Knopf
A novel arachidonic acid-selective cytosolic PLA2 contains a Ca(2+)-dependent translocation domain with homology to PKC and GAP.
Cell 1991;65(6):1043-51.
1991: E Meldrum; Ron Kriz; Nick Totty; Peter J Parker
A second gene product of the inositol-phospholipid-specific phospholipase C delta subclass.
European journal of biochemistry / FEBS 1991;196(1):159-65.
1990: Ron Kriz; L L Lin; L Sultzman; C Ellis; C H Heldin; T Pawson; J Knopf
Phospholipase C isozymes: structural and functional similarities.
Ciba Foundation symposium 1990;150():112-23; discussion 124-7.
1989: D Schaap; Peter J Parker; A Bristol; Ron Kriz; J Knopf
Unique substrate specificity and regulatory properties of PKC-epsilon: a rationale for diversity.
FEBS letters 1989;243(2):351-7.
1988: J M Wozney; V Rosen; Arkady Celeste; L M Mitsock; M J Whitters; Ron Kriz; R M Hewick; E A Wang
Novel regulators of bone formation: molecular clones and activities.
Science (New York, N.Y.) 1988;242(4885):1528-34.
1988: M Katan; Ron Kriz; Nick Totty; R Philp; E Meldrum; R A Aldape; J L Knopf; Peter J Parker
Determination of the primary structure of PLC-154 demonstrates diversity of phosphoinositide-specific phospholipase C activities.
Cell 1988;54(2):171-7.
1988: G G Wong; J S Witek-Giannotti; P A Temple; Ron Kriz; C Ferenz; R M Hewick; S C Clark; K Ikebuchi; M Ogawa
Stimulation of murine hemopoietic colony formation by human IL-6.
Journal of immunology (Baltimore, Md. : 1950) 1988;140(9):3040-4.
1988: Y C Yang; S Kovacic; Ron Kriz; Stanley Wolf; S C Clark; Thomas E Wellems; A Nienhuis; N Epstein
The human genes for GM-CSF and IL 3 are closely linked in tandem on chromosome 5.
Blood 1988;71(4):958-61.
1988: M L Stahl; C R Ferenz; K L Kelleher; Ron Kriz; J L Knopf
Sequence similarity of phospholipase C with the non-catalytic region of src.
Nature 1988;332(6161):269-72.
1988: M Katan; Ron Kriz; Nick Totty; R Philp; E Meldrum; R A Aldape; J Knopf; Peter J Parker
Primary structure of PLC-154.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():921-6.
1988: A Bristol; S M Hall; Ron Kriz; M L Stahl; Yao-Shan Fan; M G Byers; R L Eddy; TB Shows; J L Knopf
Phospholipase C-148: chromosomal location and deletion mapping of functional domains.
Cold Spring Harbor symposia on quantitative biology 1988;53 Pt 2():915-20.
1987: E Legouy; Ronald A DePinho; K Zimmerman; R Collum; G Yancopoulos; L Mitsock; Ron Kriz; F W Alt
Structure and expression of the murine L-myc gene.
The EMBO journal 1987;6(11):3359-66.
1987: Kenneth A Jacobs; David S Phelps; R Steinbrink; J Fisch; Ron Kriz; L Mitsock; J P Dougherty; H W Taeusch; Joanna Floros
Isolation of a cDNA clone encoding a high molecular weight precursor to a 6-kDa pulmonary surfactant-associated protein.
The Journal of biological chemistry 1987;262(20):9808-11.
1987: R J Jenny; D D Pittman; J J Toole; Ron Kriz; R A Aldape; R M Hewick; Randal J Kaufman; K G Mann
Complete cDNA and derived amino acid sequence of human factor V.
Proceedings of the National Academy of Sciences of the United States of America 1987;84(14):4846-50.
1987: G G Wong; P A Temple; A C Leary; J S Witek-Giannotti; Y C Yang; A B Ciarletta; M Chung; P Murtha; Ron Kriz; Randal J Kaufman
Human CSF-1: molecular cloning and expression of 4-kb cDNA encoding the human urinary protein.
Science (New York, N.Y.) 1987;235(4795):1504-8.
1987: J Ting; S K Wooden; Ron Kriz; Kerry Kelleher; Randal J Kaufman; Amy S Lee
The nucleotide sequence encoding the hamster 78-kDa glucose-regulated protein (GRP78) and its conservation between hamster and rat.
Gene 1987;55(1):147-52.
1986: Y C Yang; A B Ciarletta; P A Temple; M P Chung; S Kovacic; J S Witek-Giannotti; A C Leary; Ron Kriz; Robert E Donahue; G G Wong
Human IL-3 (multi-CSF): identification by expression cloning of a novel hematopoietic growth factor related to murine IL-3.
Cell 1986;47(1):3-10.
1986: J L Knopf; M H Lee; L A Sultzman; Ron Kriz; C R Loomis; R M Hewick; R M Bell
Cloning and expression of multiple protein kinase C cDNAs.
Cell 1986;46(4):491-502.
1986: Arkady Celeste; V Rosen; J L Buecker; Ron Kriz; E A Wang; J M Wozney
Isolation of the human gene for bone gla protein utilizing mouse and rat cDNA clones.
The EMBO journal 1986;5(8):1885-90.
1986: Joanna Floros; R Steinbrink; K Jacobs; D Phelps; Ron Kriz; M Recny; L Sultzman; S Jones; H W Taeusch; H A Frank
Isolation and characterization of cDNA clones for the 35-kDa pulmonary surfactant-associated protein.
The Journal of biological chemistry 1986;261(19):9029-33.