FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Guido Kroemer

Research Profile

Chemicals & Drugs

Anatomy

Living Beings

Physiology

Co-author Network

Publications

TOP 3
Laura Senovilla; Maria Castedo; Lorenzo Galluzzi; Guido Kroemer
Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Judith Michels; Ken A Olaussen; Cédric Oréar; Angélique Robin; Murat Saparbaev; Laura Senovilla; Jean-Charles Soria; Abdul Qader Sukkurwala; Monique Talbot; Ibtissam Talhaoui; Ilio Vitale; Gen Sheng Wu; Julien Adam; Parviz Behnam-Motlagh; Catherine Brenner; Maria Castedo; Philippe Dessen; David Pierre Enot; Lorenzo Galluzzi; Pauline Garcia; Philippe Girard; Justine Guegan; Oliver Kepp; Kimitoshi Kohno; Delphine Lissa; Guido Kroemer
Cisplatin resistance associated with PARP hyperactivation.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Guido Kroemer (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Laura Senovilla; Maria Castedo; Lorenzo Galluzzi; Guido Kroemer
Immunological control of cell cycle aberrations for the avoidance of oncogenesis: the case of tetraploidy.
Annals of the New York Academy of Sciences 2013;1284(1):57-61.
2013: Yuting Ma; Isabelle Martins; Stephen R Mattarollo; Laurie Menger; Mickaël Michaud; João Paulo Portela Catani; Frederic Schlemmer; Mark J Smyth; Eric Solary; Kim Steegh; Abdul Qader Sukkurwala; Philip R Taylor; Erika Vacchelli; Peter van Endert; Takahiro Yamazaki; Heng Yang; Laurence Zitvogel; Sandy Adjemian; Laetitia Aymeric; Nathalie Droin; Helene Duret; Lorenzo Galluzzi; Siamon Gordon; Dalil Hannani; Oliver Kepp; Roman Krzysiek; Guido Kroemer
Anticancer chemotherapy-induced intratumoral recruitment and differentiation of antigen-presenting cells.
Immunity 2013;38(4):729-41.
2013: Judith Michels; Ken A Olaussen; Cédric Oréar; Angélique Robin; Murat Saparbaev; Laura Senovilla; Jean-Charles Soria; Abdul Qader Sukkurwala; Monique Talbot; Ibtissam Talhaoui; Ilio Vitale; Gen Sheng Wu; Julien Adam; Parviz Behnam-Motlagh; Catherine Brenner; Maria Castedo; Philippe Dessen; David Pierre Enot; Lorenzo Galluzzi; Pauline Garcia; Philippe Girard; Justine Guegan; Oliver Kepp; Kimitoshi Kohno; Delphine Lissa; Guido Kroemer
Cisplatin resistance associated with PARP hyperactivation.
Cancer research 2013;73(7):2271-80.
2013: Judith Michels; Ken A Olaussen; Laura Senovilla; Jean-Charles Soria; Ilio Vitale; Catherine Brenner; Maria Castedo; David P Enot; Pauline Garcia; Delphine Lissa; Guido Kroemer
Synergistic interaction between cisplatin and PARP inhibitors in non-small cell lung cancer.
Cell cycle (Georgetown, Tex.) 2013;12(6):877-83.
2013: Mireia Niso-Santano; Laura Senovilla; Shensi Shen; Sandy Adjemian; Lorenzo Galluzzi; Oliver Kepp; Sylvie Lachkar; Maria Chiara Maiuri; Shoaib Ahmad Malik; Guillermo Mariño; Guido Kroemer
Direct interaction between STAT3 and EIF2AK2 controls fatty acid-induced autophagy.
Autophagy 2013;9(3):415-7.
2013: Sabrina Büttner; G Callewaert; Didac Carmona-Gutierrez; P D'hooge; Tobias Eisenberg; L Faes; Vanessa Franssens; P Freudenberger; R Ghillebert; L Habernig; A Harger; N Kourtis; Guido Kroemer; T R Pieber; W N Reichelt; Doris Ruli; Stephan J Sigrist; N Tavernarakis; Joris Winderickx; S Benke; F Broeskamp; Frank Madeo
The Ca2+/Mn2+ ion-pump PMR1 links elevation of cytosolic Ca(2+) levels to α-synuclein toxicity in Parkinson's disease models.
Cell death and differentiation 2013;20(3):465-77.
2013: Lorenzo Galluzzi; Aicha Goubar; Carmen Behrens; Benjamin Besse; Nicolas Dorvault; Pierre Fouret; Judith Michels; Ken A Olaussen; Angélique Robin; Laura Senovilla; Jean-Charles Soria; Pierre Validire; Ilio Vitale; Ignacio Ivan Wistuba; Guido Kroemer
Prognostic value of LIPC in non-small cell lung carcinoma.
Cell cycle (Georgetown, Tex.) 2013;12(4):647-54.
2013: Alice Boilève; Maria Castedo; Hans Clevers; Lorenzo Galluzzi; Delphine Lissa; Isabelle Martins; Didier Métivier; Laura Senovilla; Stieneke van den Brink; Ilio Vitale; Guido Kroemer
Immunosurveillance against tetraploidization-induced colon tumorigenesis.
Cell cycle (Georgetown, Tex.) 2013;12(3):473-9.
2013: Lorenzo Galluzzi; Pauline Garcia; Maria Castedo; Etienne Chatelut; Sabrina Marsili; Judith Michels; Laura Senovilla; Erika Vacchelli; Ilio Vitale; Guido Kroemer
Vitamin B6 metabolism influences the intracellular accumulation of cisplatin.
Cell cycle (Georgetown, Tex.) 2013;12(3):417-21.
2013: Maria Anna Bauer; Didac Carmona-Gutiérrez; Tobias Eisenberg; Kai-Uwe Fröhlich; Helmut Jungwirth; Guido Kroemer; Christoph Magnes; Evgenia V Megalou; Thomas R Pieber; Angela Reisenbichler; Christoph Ruckenstuhl; Frank Sinner; Nektarios Tavernarakis; Frank Madeo
Spermidine promotes mating and fertilization efficiency in model organisms.
Cell cycle (Georgetown, Tex.) 2013;12(2):346-52.
2013: Judith Michels; Laura Senovilla; Maria Castedo; Oliver Kepp; Guido Kroemer; Delphine Lissa; Lorenzo Galluzzi
Functions of BCL-X L at the Interface between Cell Death and Metabolism.
International journal of cell biology 2013;2013():705294.
2013: Alexander Valent; Frédérique Penault-Llorca; Anne Cayre; Guido Kroemer
Change in HER2 (ERBB2) gene status after taxane-based chemotherapy for breast cancer: polyploidization can lead to diagnostic pitfalls with potential impact for clinical management.
Cancer genetics 2013;206(1-2):37-41.
2013: Oliver Kepp; Sandy Adjemian; Lorenzo Galluzzi; Isabelle Martins; Laurie Menger; Mickaël Michaud; Abdul Qader Sukkurwala; Guido Kroemer
Quantification of cell cycle-arresting proteins.
Methods in molecular biology (Clifton, N.J.) 2013;965():121-42.
2013: Ilio Vitale; Didier Metivier; Maria Castedo; Lorenzo Galluzzi; Mohamed Jemaà; Guido Kroemer
Cytofluorometric assessment of cell cycle progression.
Methods in molecular biology (Clifton, N.J.) 2013;965():93-120.
2013: Guido Kroemer; Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel
Immunogenic cell death in cancer therapy.
Annual review of immunology 2013;31():51-72.
2012: Shensi Shen; Sylvie Souquere; Tetsuo Takehara; Sandy Adjemian; Lorenzo Galluzzi; Hayato Hikita; Oliver Kepp; Romano Kroemer; Sylvie Lachkar; Maria Chiara Maiuri; Shoaib Ahmad Malik; Guillermo Mariño; Hervé Minoux; Mireia Niso-Santano; Gérard Pierron; Laura Senovilla; Guido Kroemer
Cytoplasmic STAT3 represses autophagy by inhibiting PKR activity.
Molecular cell 2012;48(5):667-80.
2012: Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
Mitochondria: master regulators of danger signalling.
Nature reviews. Molecular cell biology 2012;13(12):780-8.
2012: Laura Senovilla; Ilio Vitale; Maria Castedo; Lorenzo Galluzzi; Guillermo Marino; Guido Kroemer
Immunosurveillance against cancer-associated hyperploidy.
Oncotarget 2012;3(11):1270-1.
2012: Audrey Paoletti; Marina Caillet; Guido Kroemer; Frédéric Law; Juliana Pipoli da Fonseca; Syed Qasim RAZA; Laurent Voisin; Jean-Luc PERFETTINI
Multifaceted roles of purinergic receptors in viral infection.
Microbes and infection / Institut Pasteur 2012;14(14):1278-83.
2012: Lorenzo Galluzzi; Oliver Kepp; Christina Trojel-Hansen; Guido Kroemer
Mitochondrial control of cellular life, stress, and death.
Circulation research 2012;111(9):1198-207.
2012: Lorenzo Galluzzi; Philippe Hupé; Nora Jägemann; Emmanuel Barillot; Didac Carmona-Gutierrez; Philippe Dessen; Tobias Eisenberg; Vladimir Lazar; Frank Madeo; Caroline Paccard; Hugues Ripoche; Thomas Robert; Laura Senovilla; Nicolas Servant; Erika Vacchelli; Ilio Vitale; Hans Zischka; Guido Kroemer
Independent transcriptional reprogramming and apoptosis induction by cisplatin.
Cell cycle (Georgetown, Tex.) 2012;11(18):3472-80.
2012: M Tailler; S Thépot; V Baud; K Billot; Simone Boehrer; P Fenaux; L Galluzzi; Guido Kroemer; E Lainey; Didier Métivier; M Sébert; Laura Senovilla; O Kepp
Antineoplastic activity of ouabain and pyrithione zinc in acute myeloid leukemia.
Oncogene 2012;31(30):3536-46.
2012: Laurie Menger; Mickaël Michaud; Grégoire Mignot; Nazanine Modjtahedi; Frederic Schlemmer; Shensi Shen; Abdul Qader Sukkurwala; Eric Sulpice; Erika Vacchelli; Takahiro Yamazaki; Laurence Zitvogel; Sandy Adjemian; Fabrice André; Lorenzo Galluzzi; François Ghiringhelli; Xavier Gidrol; Oliver Kepp; Clara Locher; Yuting Ma; Isabelle Martins; Guido Kroemer
Cardiac glycosides exert anticancer effects by inducing immunogenic cell death.
Science translational medicine 2012;4(143):143ra99.
2012: Didac Carmona-Gutierrez; Guido Kroemer; Frank Madeo
When death was young: an ancestral apoptotic network in bacteria.
Molecular cell 2012;46(5):552-4.
2012: L Galluzzi; O Kepp; Guido Kroemer
Caspase-3 and prostaglandins signal for tumor regrowth in cancer therapy.
Oncogene 2012;31(23):2805-8.
2012: Laurence Zitvogel; Isabelle Martins; Laetitia Aymeric; Dalil Hannani; Oliver Kepp; Guido Kroemer
[Antitumoral immunization during cancer chemotherapy].
Bulletin de l'Académie nationale de médecine 2012;196(6):1075-86.
2012: Mohamed Jemaà; Oliver Kepp; Antonio Antoccia; Francesco Berardinelli; Alice Boilève; Maria Castedo; Lorenzo Galluzzi; Francis Harper; Delphine Lissa; Gérard Pierron; Laura Senovilla; Ilio Vitale; Guido Kroemer
Preferential killing of p53-deficient cancer cells by reversine.
Cell cycle (Georgetown, Tex.) 2012;11(11):2149-58.
2012: Didac Carmona-Gutierrez; Guido Kroemer; A Andryushkova; C Sommer; Frank Madeo
A higher spirit: avoiding yeast suicide during alcoholic fermentation.
Cell death and differentiation 2012;19(6):913-4.
2012: Mohamed Jemaà; Oliver Kepp; Antonio Antoccia; Francesco Berardinelli; Maria Castedo; Lorenzo Galluzzi; Francis Harper; Delphine Lissa; Shoaib Ahmad Malik; Guillermo Mariño; Gérard Pierron; Santiago Rello-Varona; Frederic Schlemmer; Laura Senovilla; Maximilien Tailler; Ilio Vitale; Guido Kroemer
Selective killing of p53-deficient cancer cells by SP600125.
EMBO molecular medicine 2012;4(6):500-14.
2012: Magali Terme; Evelyn Ullrich; Sophie Viaud; Hideo Yagita; Laetitia Aymeric; Nathalie Chaput; Lieping Chen; Jerome Coudert; Mariapia Degli-Esposti; Mélanie Desbois; François Ghiringhelli; Gilles Kaplanski; Masashi Kato; Guido Kroemer; Salaheddine Mécheri; Kathrin Meinhardt; Armelle Prévost-Blondel; Bernard Ryffel; Joachim L Schultze; Eric Tartour; Laurence Zitvogel
Cancer-induced immunosuppression: IL-18-elicited immunoablative NK cells.
Cancer research 2012;72(11):2757-67.
2012: Diego A Rodriguez; Diego Rojas-Rivera; Hery Urra; Tomas Vaisar; Sebastian Zamorano; Emily H Cheng; Ricardo Armisen; Juan R Cubillos-Ruiz; Christian Gonzalez-Billault; Daniel R Henriquez; Thergiory Irrazabal; Guido Kroemer; Anthony Letai; Michal Letek; Fernanda Lisbona; Felipe X Pimentel-Muiños; Claudio A Hetz
BH3-only proteins are part of a regulatory network that control the sustained signalling of the unfolded protein response sensor IRE1α.
The EMBO journal 2012;31(10):2322-35.
2012: Lorenzo Galluzzi; Guido Kroemer
Autophagy mediates the metabolic benefits of endurance training.
Circulation research 2012;110(10):1276-8.
2012: Lorenzo Galluzzi; Oliver Kepp; Christina Trojel-Hansen; Guido Kroemer
Non-apoptotic functions of apoptosis-regulatory proteins.
EMBO reports 2012;13(4):322-30.
2012: Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
Reverse Warburg: straight to cancer.
Cell cycle (Georgetown, Tex.) 2012;11(6):1059.
2012: Lorenzo Galluzzi; Laura Senovilla; Laurence Zitvogel; Guido Kroemer
The secret ally: immunostimulation by anticancer drugs.
Nature reviews. Drug discovery 2012;11(3):215-33.
2012: Alfredo Criollo; Lorenzo Galluzzi; Véronique Baud; Fanny Chereau; Maria Chiara Maiuri; Shoaib Ahmad Malik; Guillermo Mariño; Mireia Niso-Santano; Guido Kroemer
Autophagy is required for the activation of NFκB.
Cell cycle (Georgetown, Tex.) 2012;11(1):194-9.
2012: Lorenzo Galluzzi; Oliver Kepp; Maria Chiara Maiuri; Eugenia Morselli; Ilio Vitale; Aména Ben Younes; Guido Kroemer
Evaluation of rapamycin-induced cell death.
Methods in molecular biology (Clifton, N.J.) 2012;821():125-69.
2011: Elodie Lainey; Marie Sébert; Maximilien Tailler; Sylvain Thépot; Cyrielle Bouteloup; Stéphane de Botton; Pierre Fenaux; Claude Gardin; Guido Kroemer; Lionel Adès; André Baruchel; Simone Boehrer
Tyrosine kinase inhibitors for the treatment of acute myeloid leukemia: delineation of anti-leukemic mechanisms of action.
Biochemical pharmacology 2011;82(10):1457-66.
2011: Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
FADD: an endogenous inhibitor of RIP3-driven regulated necrosis.
Cell research 2011;21(10):1383-5.
2011: Simone Boehrer; Cyrielle Bouteloup; Stéphane de Botton; Pierre Fenaux; Lorenzo Galluzzi; Claude Gardin; Francis Harper; Elodie Lainey; Gérard Pierron; Marie Sébert; Maximilien Tailler; Sylvain Thépot; Lionel Adès; Guido Kroemer
Erlotinib antagonizes constitutive activation of SRC family kinases and mTOR in acute myeloid leukemia.
Cell cycle (Georgetown, Tex.) 2011;10(18):3168-75.
2011: Lorenzo Galluzzi; Oliver Kepp; Eugenia Morselli; Marcello Pinti; Ilio Vitale; Guido Kroemer
Mitochondrial liaisons of p53.
Antioxidants & redox signaling 2011;15(6):1691-714.
2011: Isabelle Martins; Lorenzo Galluzzi; Guido Kroemer
Hormesis, cell death and aging.
Aging 2011;3(9):821-8.
2011: Laurence Zitvogel; Guido Kroemer
Anticancer effects of imatinib via immunostimulation.
Nature medicine 2011;17(9):1050-1.
2011: Simone Boehrer; Elodie Lainey; Guido Kroemer
Coordinated epigenetic regulation of autophagy and apoptosis.
Cell cycle (Georgetown, Tex.) 2011;10(17):2832-3.
2011: Shoaib Ahmad Malik; Guillermo Mariño; Shensi Shen; Amena BenYounès; Francis Harper; Maria Chiara Maiuri; Guido Kroemer
Neuroendocrine regulation of autophagy by leptin.
Cell cycle (Georgetown, Tex.) 2011;10(17):2917-23.
2011: Wolf Herman Fridman; Jérôme Galon; Franck Pagès; Catherine Sautès-Fridman; Eric Tartour; Guido Kroemer
Prognostic and predictive impact of intra- and peritumoral immune infiltrates.
Cancer research 2011;71(17):5601-5.
2011: Eugenia Morselli; Christoph Ruckenstuhl; Shensi Shen; Maria Anna Bauer; Tokuhiro Chano; Alfredo Criollo; Lorenzo Galluzzi; Frank Madeo; Maria Chiara Maiuri; Guillermo Mariño; Mickael Michaud; Guido Kroemer
p53 inhibits autophagy by interacting with the human ortholog of yeast Atg17, RB1CC1/FIP200.
Cell cycle (Georgetown, Tex.) 2011;10(16):2763-9.
2011: Magali Terme; Evelyn Ullrich; Laetitia Aymeric; Kathrin Meinhardt; Mélanie Desbois; Nicolas Delahaye; Sophie Viaud; Bernard Ryffel; Hideo Yagita; Gilles Kaplanski; Armelle Prévost-Blondel; Masashi Kato; Joachim L Schultze; Eric Tartour; Guido Kroemer; Nathalie Chaput; Laurence Zitvogel
IL-18 induces PD-1-dependent immunosuppression in cancer.
Cancer research 2011;71(16):5393-9.
2011: Amena BenYounès; Oliver Kepp; Maria Chiara Maiuri; Shoaib Ahmad Malik; Didier Métivier; Shensi Shen; Maximilien Tailler; Nicolas Tajeddine; Ilio Vitale; Guido Kroemer
A fluorescence-microscopic and cytofluorometric system for monitoring the turnover of the autophagic substrate p62/SQSTM1.
Autophagy 2011;7(8):883-91.
2011: Sabrina Büttner; Didac Carmona-Gutierrez; Tobias Eisenberg; Kai-Uwe Fröhlich; Lorenzo Galluzzi; Lukas Habernig; Oliver Kepp; Chamel Khoury; Guido Kroemer; Peter Laun; Chris Meisinger; Barbara Moitzi; Gerald Rechberger; Patrick Rockenfeller; Doris Ruli; F-Nora Vögtle; Michael Breitenbach; Frank Madeo
A yeast BH3-only protein mediates the mitochondrial pathway of apoptosis.
The EMBO journal 2011;30(14):2779-92.
2011: Eugenia Morselli; Lorenzo Galluzzi; Oliver Kepp; Guillermo Mariño; Mickael Michaud; Ilio Vitale; Maria Chiara Maiuri; Guido Kroemer
Oncosuppressive functions of autophagy.
Antioxidants & redox signaling 2011;14(11):2251-69.
2011: Guillermo Mariño; Isabelle Martins; Guido Kroemer
Autophagy in Ras-induced malignant transformation: fatal or vital?
Molecular cell 2011;42(1):1-3.
2011: Hans Zischka; Josef Lichtmannegger; Sabine Schmitt; Nora Jägemann; Sabine Schulz; Daniela Wartini; Luise Jennen; Christian Rust; Nathanael Larochette; Lorenzo Galluzzi; Veronique Chajes; Nathan Bandow; Valérie S Gilles; Alan A DiSpirito; Irene Esposito; Martin Goettlicher; Karl H Summer; Guido Kroemer
Liver mitochondrial membrane crosslinking and destruction in a rat model of Wilson disease.
The Journal of clinical investigation 2011;121(4):1508-18.
2011: Guillermo Mariño; Frank Madeo; Guido Kroemer
Autophagy for tissue homeostasis and neuroprotection.
Current opinion in cell biology 2011;23(2):198-206.
2011: Christophe Massard; Jean-Charles Soria; D Alan Anthoney; A Proctor; Angela Scaburri; Maria Adele Pacciarini; Bernard Laffranchi; Cinzia Pellizzoni; Guido Kroemer; Jean-Pierre Armand; Rastilav Balheda; Christopher J Twelves
A first in man, phase I dose-escalation study of PHA-793887, an inhibitor of multiple cyclin-dependent kinases (CDK2, 1 and 4) reveals unexpected hepatotoxicity in patients with solid tumors.
Cell cycle (Georgetown, Tex.) 2011;10(6):963-70.
2011: Yuting Ma; Laetitia Aymeric; Clara Locher; Stephen R Mattarollo; Nicolas F Delahaye; Pablo Pereira; Laurent Boucontet; Lionel Apetoh; François Ghiringhelli; Noelia Casares; Juan José Lasarte; Goro Matsuzaki; Koichi Ikuta; Bernard Ryffel; Kamel Benlagha; Antoine Tesnière; Nicolas Ibrahim; Julie Déchanet-Merville; Nathalie Chaput; Mark J Smyth; Guido Kroemer; Laurence Zitvogel
Contribution of IL-17-producing gamma delta T cells to the efficacy of anticancer chemotherapy.
The Journal of experimental medicine 2011;208(3):491-503.
2011: Oliver Kepp; Lorenzo Galluzzi; Guido Kroemer
Mitochondrial control of the NLRP3 inflammasome.
Nature immunology 2011;12(3):199-200.
2011: Yuting Ma; R Conforti; Laetitia Aymeric; Clara Locher; Oliver Kepp; Guido Kroemer; Laurence Zitvogel
How to improve the immunogenicity of chemotherapy and radiotherapy.
Cancer metastasis reviews 2011;30(1):71-82.
2011: Oliver Kepp; Lorenzo Galluzzi; Isabelle Martins; Frederic Schlemmer; Sandy Adjemian; Mickael Michaud; Abdul Qader Sukkurwala; Laurie Menger; Laurence Zitvogel; Guido Kroemer
Molecular determinants of immunogenic cell death elicited by anticancer chemotherapy.
Cancer metastasis reviews 2011;30(1):61-9.
2011: Eugenia Morselli; Guillermo Mariño; Martin V Bennetzen; Tobias Eisenberg; Evgenia Megalou; Sabrina Schroeder; Sandra Cabrera; Paule Bénit; Pierre Rustin; Alfredo Criollo; Oliver Kepp; Lorenzo Galluzzi; Shensi Shen; Shoaib Ahmad Malik; Maria Chiara Maiuri; Yoshiyuki Horio; Carlos López-Otín; Jens S Andersen; Nektarios Tavernarakis; Frank Madeo; Guido Kroemer
Spermidine and resveratrol induce autophagy by distinct pathways converging on the acetylproteome.
The Journal of cell biology 2011;192(4):615-29.
2011: Lionel Apetoh; Clara Locher; François Ghiringhelli; Guido Kroemer; Laurence Zitvogel
Harnessing dendritic cells in cancer.
Seminars in immunology 2011;23(1):42-9.
2011: Lorenzo Galluzzi; Erika Vacchelli; Ilio Vitale; Guido Kroemer
Cell death signaling and anticancer therapy.
Frontiers in oncology 2011;1():5.
2011: Lorenzo Galluzzi; Ilio Vitale; Guido Kroemer
Past, present, and future of molecular and cellular oncology.
Frontiers in oncology 2011;1():1.
2011: Wolf H Fridman; Jérôme Galon; Franck Pagès; Catherine Sautès-Fridman; Eric Tartour; Jean-Luc Teillaud; Laurence Zitvogel; Jessica Zucman-Rossi; Guido Kroemer
The ultimate goal of curative anti-cancer therapies: inducing an adaptive anti-tumor immune response.
Frontiers in immunology 2011;2():66.
2010: Junying Yuan; Guido Kroemer
Alternative cell death mechanisms in development and beyond.
Genes & development 2010;24(23):2592-602.
2010: Clara Locher; R Conforti; Laetitia Aymeric; Yuting Ma; Takahiro Yamazaki; Sylvie Rusakiewicz; Antoine Tesnière; François Ghiringhelli; Lionel Apetoh; Yannis Morel; Jean-Philippe Girard; Guido Kroemer; Laurence Zitvogel
Desirable cell death during anticancer chemotherapy.
Annals of the New York Academy of Sciences 2010;1209():99-108.
2010: Nazanine Modjtahedi; F Giordanetto; Guido Kroemer
A human mitochondriopathy caused by AIF mutation.
Cell death and differentiation 2010;17(10):1525-8.
2010: Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
TP53 and MTOR crosstalk to regulate cellular senescence.
Aging 2010;2(9):535-7.
2010: Frank Madeo; Nektarios Tavernarakis; Guido Kroemer
Can autophagy promote longevity?
Nature cell biology 2010;12(9):842-6.
2010: Oliver Kepp; Abdelaziz Gdoura; Isabelle Martins; Theocharis Panaretakis; Frederic Schlemmer; Antoine Tesniere; Gian Maria Fimia; Fabiola Ciccosanti; Anne Burgevin; Mauro Piacentini; Paul Eggleton; Philip J Young; Laurence Zitvogel; Peter van Endert; Guido Kroemer
Lysyl tRNA synthetase is required for the translocation of calreticulin to the cell surface in immunogenic death.
Cell cycle (Georgetown, Tex.) 2010;9(15):3072-7.
2010: Guido Kroemer
Tetraploid cancer cell precursors.
Nature reviews. Molecular cell biology 2010;11(8):539.
2010: Mario Chiong; V Parra; Verónica Eisner; Cristian Ibarra; C Maldonado; Alfredo Criollo; R Bravo; Clara Quiroga; A Contreras; José Miguel Vicencio; P Cea; J L Bucarey; Jordi Molgó; Enrique Jaimovich; Cecilia Hidalgo; Guido Kroemer; Sergio Lavandero
Parallel activation of Ca(2+)-induced survival and death pathways in cardiomyocytes by sorbitol-induced hyperosmotic stress.
Apoptosis : an international journal on programmed cell death 2010;15(8):887-903.
2010: Ilio Vitale; Mohamed Jemaà; Laura Senovilla; Lorenzo Galluzzi; Santiago Rello-Varona; Didier Metivier; Hugues Ripoche; Vladimir Lazar; Philippe Dessen; Maria Castedo; Guido Kroemer
Involvement of p38alpha in the mitotic progression of p53(-/-) tetraploid cells.
Cell cycle (Georgetown, Tex.) 2010;9(14):2823-9.
2010: Antoine Tesniere; Nassera Abermil; Frederic Schlemmer; Noelia Casares; Oliver Kepp; Marie Pequignot; Mickael Michaud; Isabelle Martins; Laura Senovilla; Laurence Zitvogel; Guido Kroemer
In vivo depletion of T lymphocyte-specific transcription factors by RNA interference.
Cell cycle (Georgetown, Tex.) 2010;9(14):2830-5.
2010: Patrick Rockenfeller; Julia Ring; Vera Muschett; Andreas Beranek; Sabrina Buettner; Didac Carmona-Gutierrez; Tobias Eisenberg; Chamel Khoury; Gerald Rechberger; Sepp D Kohlwein; Guido Kroemer; Frank Madeo
Fatty acids trigger mitochondrion-dependent necrosis.
Cell cycle (Georgetown, Tex.) 2010;9(14):2836-42.
2010: E Hangen; D De Zio; M Bordi; Changlian Zhu; Philippe Dessen; F Caffin; S Lachkar; Jean-Luc PERFETTINI; Vladimir Lazar; J Benard; G M Fimia; Mauro Piacentini; Francis Harper; Gérard Pierron; J M Vicencio; Paule Bénit; A de Andrade; G Höglinger; C Culmsee; Pierre Rustin; Klas Blomgren; F Cecconi; Guido Kroemer; Nazanine Modjtahedi
A brain-specific isoform of mitochondrial apoptosis-inducing factor: AIF2.
Cell death and differentiation 2010;17(7):1155-66.
2010: Lorenzo Galluzzi; O Kepp; E Morselli; Ilio Vitale; Laura Senovilla; M Pinti; Laurence Zitvogel; Guido Kroemer
Viral strategies for the evasion of immunogenic cell death.
Journal of internal medicine 2010;267(5):526-42.
2010: Emilie Hangen; Klas Blomgren; Paule Bénit; Guido Kroemer; Nazanine Modjtahedi
Life with or without AIF.
Trends in biochemical sciences 2010;35(5):278-87.
2010: Didac Carmona-Gutierrez; Tobias Eisenberg; Sabrina Büttner; C Meisinger; Guido Kroemer; Frank Madeo
Apoptosis in yeast: triggers, pathways, subroutines.
Cell death and differentiation 2010;17(5):763-73.
2010: Jean-Luc PERFETTINI; R Nardacci; C Séror; Syed Qasim RAZA; S Sepe; H Saïdi; F Brottes; A Amendola; F Subra; F Del Nonno; L Chessa; A D'Incecco; M-L Gougeon; M Piacentini; Guido Kroemer
53BP1 represses mitotic catastrophe in syncytia elicited by the HIV-1 envelope.
Cell death and differentiation 2010;17(5):811-20.
2010: Maria Chiara Maiuri; Lorenzo Galluzzi; Eugenia Morselli; Oliver Kepp; Shoaib Ahmad Malik; Guido Kroemer
Autophagy regulation by p53.
Current opinion in cell biology 2010;22(2):181-5.
2010: Oliver Kepp; Lorenzo Galluzzi; Laurence Zitvogel; Guido Kroemer
Pyroptosis - a cell death modality of its kind?
European journal of immunology 2010;40(3):627-30.
2010: Didac Carmona-Gutierrez; K-U Fröhlich; Guido Kroemer; Frank Madeo
Metacaspases are caspases. Doubt no more.
Cell death and differentiation 2010;17(3):377-8.
2010: Lorenzo Galluzzi; Eugenia Morselli; Ilio Vitale; Oliver Kepp; Laura Senovilla; Alfredo Criollo; Nicolas Servant; Caroline Paccard; Philippe Hupé; Thomas Robert; Hugues Ripoche; Vladimir Lazar; Annick Harel-Bellan; Philippe Dessen; Emmanuel Barillot; Guido Kroemer
miR-181a and miR-630 regulate cisplatin-induced cancer cell death.
Cancer research 2010;70(5):1793-803.
2010: Ralf J Braun; Sabrina Büttner; Julia Ring; Guido Kroemer; Frank Madeo
Nervous yeast: modeling neurotoxic cell death.
Trends in biochemical sciences 2010;35(3):135-44.
2010: Lorenzo Galluzzi; Oliver Kepp; Laurence Zitvogel; Guido Kroemer
Bacterial invasion: linking autophagy and innate immunity.
Current biology : CB 2010;20(3):R106-8.
2010: Maria Chiara Maiuri; Alfredo Criollo; Guido Kroemer
Crosstalk between apoptosis and autophagy within the Beclin 1 interactome.
The EMBO journal 2010;29(3):515-6.
2010: Alfredo Criollo; Laura Senovilla; Hélène Authier; Maria Chiara Maiuri; Eugenia Morselli; Ilio Vitale; Oliver Kepp; Ezgi Tasdemir; Lorenzo Galluzzi; Shensi Shen; Maximilien Tailler; Nicolas Delahaye; Antoine Tesniere; Daniela De Stefano; Aména Ben Younes; Francis Harper; Gérard Pierron; Sergio Lavandero; Laurence Zitvogel; Alain Israel; Véronique Baud; Guido Kroemer
The IKK complex contributes to the induction of autophagy.
The EMBO journal 2010;29(3):619-31.
2010: Lorenzo Galluzzi; Eugenia Morselli; Oliver Kepp; Ilio Vitale; Alice Rigoni; Erika Vacchelli; Mickael Michaud; Hans Zischka; Maria Castedo; Guido Kroemer
Mitochondrial gateways to cancer.
Molecular aspects of medicine 2010;31(1):1-20.
2010: Antoine Tesniere; F Schlemmer; V Boige; O Kepp; I Martins; François Ghiringhelli; L Aymeric; M Michaud; Lionel Apetoh; L Barault; J Mendiboure; J-P Pignon; V Jooste; Peter van Endert; M Ducreux; Laurence Zitvogel; F Piard; Guido Kroemer
Immunogenic death of colon cancer cells treated with oxaliplatin.
Oncogene 2010;29(4):482-91.
2010: R Conforti; Yuting Ma; Yannis Morel; Carine Paturel; Magali Terme; Sophie Viaud; Bernhard RYFFEL; Maria Ferrantini; Ravindra Uppaluri; Robert Schreiber; Christophe Combadière; Nathalie Chaput; Fabrice André; Guido Kroemer; Laurence Zitvogel
Opposing effects of toll-like receptor (TLR3) signaling in tumors can be therapeutically uncoupled to optimize the anticancer efficacy of TLR3 ligands.
Cancer research 2010;70(2):490-500.
2010: Shensi Shen; Oliver Kepp; Isabelle Martins; Ilio Vitale; Sylvie Souquère; Maria Castedo; Gérard Pierron; Guido Kroemer
Defective autophagy associated with LC3 puncta in epothilone-resistant cancer cells.
Cell cycle (Georgetown, Tex.) 2010;9(2):377-83.
2010: Lorenzo Galluzzi; Eugenia Morselli; Oliver Kepp; Maria Chiara Maiuri; Guido Kroemer
Defective autophagy control by the p53 rheostat in cancer.
Cell cycle (Georgetown, Tex.) 2010;9(2):250-5.
2010: Guillermo Mariño; Guido Kroemer
Ammonia: a diffusible factor released by proliferating cells that induces autophagy.
Science signaling 2010;3(124):pe19.
2010: Frank Madeo; Tobias Eisenberg; Sabrina Büttner; Christoph Ruckenstuhl; Guido Kroemer
Spermidine: a novel autophagy inducer and longevity elixir.
Autophagy 2010;6(1):160-2.
2010: Alfredo Criollo; Laura Senovilla; Hélène Authier; Maria Chiara Maiuri; Eugenia Morselli; Ilio Vitale; Oliver Kepp; Ezgi Tasdemir; Lorenzo Galluzzi; Shensi Shen; Maximilien Tailler; Nicolas Delahaye; Antoine Tesniere; Daniela De Stefano; Aména Ben Younes; Francis Harper; Gérard Pierron; Sergio Lavandero; Laurence Zitvogel; Alain Israel; Véronique Baud; Guido Kroemer
IKK connects autophagy to major stress pathways.
Autophagy 2010;6(1):189-91.
2010: Eugenia Morselli; Maria Chiara Maiuri; Maria Markaki; Evgenia Megalou; Angela Pasparaki; Konstantinos Palikaras; Alfredo Criollo; Lorenzo Galluzzi; Shoaib Ahmad Malik; Ilio Vitale; Mickael Michaud; Frank Madeo; Nektarios Tavernarakis; Guido Kroemer
The life span-prolonging effect of sirtuin-1 is mediated by autophagy.
Autophagy 2010;6(1):186-8.
2009: Tommaso Moschetti; Alessandro Giuffrè; Chiara Ardiccioni; beatrice vallone; Nazanine Modjtahedi; Guido Kroemer; Maurizio Brunori
Failure of apoptosis-inducing factor to act as neuroglobin reductase.
Biochemical and biophysical research communications 2009;390(1):121-4.
2009: Eugenia Morselli; Lorenzo Galluzzi; Oliver Kepp; Alfredo Criollo; Maria Chiara Maiuri; Nektarios Tavernarakis; Frank Madeo; Guido Kroemer
Autophagy mediates pharmacological lifespan extension by spermidine and resveratrol.
Aging 2009;1(12):961-70.
2009: Oliver Kepp; Lorenzo Galluzzi; Fabrizio Giordanetto; Antoine Tesniere; Ilio Vitale; Isabelle Martins; Frederic Schlemmer; Sandy Adjemian; Laurence Zitvogel; Guido Kroemer
Disruption of the PP1/GADD34 complex induces calreticulin exposure.
Cell cycle (Georgetown, Tex.) 2009;8(23):3971-7.
2009: Isabelle Martins; Antoine Tesniere; Oliver Kepp; Mickael Michaud; Frederic Schlemmer; Laura Senovilla; Claire Séror; Didier Métivier; Jean-Luc PERFETTINI; Laurence Zitvogel; Guido Kroemer
Chemotherapy induces ATP release from tumor cells.
Cell cycle (Georgetown, Tex.) 2009;8(22):3723-8.
2009: Tobias Eisenberg; Heide Knauer; Alexandra Schauer; Sabrina Büttner; Christoph Ruckenstuhl; Didac Carmona-Gutierrez; Julia Ring; Sabrina Schroeder; Christoph Magnes; Lucia Antonacci; Heike Fussi; Luiza Deszcz; Regina Hartl; Elisabeth Schraml; Alfredo Criollo; Evgenia Megalou; Daniela Weiskopf; Peter Laun; Gino Heeren; Michael Breitenbach; Beatrix Grubeck-Loebenstein; Eva Herker; Birthe Fahrenkrog; Kai-Uwe Fröhlich; Frank Sinner; Nektarios Tavernarakis; Nadege Minois; Guido Kroemer; Frank Madeo
Induction of autophagy by spermidine promotes longevity.
Nature cell biology 2009;11(11):1305-14.
2009: Lorenzo Galluzzi; Fabrizio Giordanetto; Guido Kroemer
Targeting HSP70 for cancer therapy.
Molecular cell 2009;36(2):176-7.
2009: Frank Madeo; Tobias Eisenberg; Guido Kroemer
Autophagy for the avoidance of neurodegeneration.
Genes & development 2009;23(19):2253-9.
2009: Yungan Tao; Céline Leteur; Julien Calderaro; Fiona Girdler; Ping Zhang; Valérie Frascogna; Mariana Varna; Paule Opolon; Maria Castedo; Jean Bourhis; Guido Kroemer; Eric Deutsch
The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe.
Cell cycle (Georgetown, Tex.) 2009;8(19):3172-81.
2009: Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
RIP kinases initiate programmed necrosis.
Journal of molecular cell biology 2009;1(1):8-10.
2009: Clara Locher; Sylvie Rusakiewicz; Antoine Tesnière; François Ghiringhelli; Lionel Apetoh; Guido Kroemer; Laurence Zitvogel
Witch hunt against tumor cells enhanced by dendritic cells.
Annals of the New York Academy of Sciences 2009;1174():51-60.
2009: Eugenia Morselli; Lorenzo Galluzzi; Oliver Kepp; José-Miguel Vicencio; Alfredo Criollo; Maria Chiara Maiuri; Guido Kroemer
Anti- and pro-tumor functions of autophagy.
Biochimica et biophysica acta 2009;1793(9):1524-32.
2009: Magali Terme; Grégoire Mignot; Evelyn Ullrich; Mathieu Bonmort; Véronique Minard-Colin; Alexandra Jacquet; Joachim L Schultze; Guido Kroemer; CLAUDE LECLERC; Nathalie Chaput; Laurence Zitvogel
The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells.
Cancer research 2009;69(16):6590-7.
2009: Nicholas Joza; J Andrew Pospisilik; Emilie Hangen; Toshikatsu Hanada; Nazanine Modjtahedi; Josef M Penninger; Guido Kroemer
AIF: not just an apoptosis-inducing factor.
Annals of the New York Academy of Sciences 2009;1171():2-11.
2009: Alfredo Criollo; Philippe Dessen; Guido Kroemer
DRAM: a phylogenetically ancient regulator of autophagy.
Cell cycle (Georgetown, Tex.) 2009;8(15):2319-20.
2009: Laurence Zitvogel; Guido Kroemer
Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects.
The Journal of clinical investigation 2009;119(8):2127-30.
2009: Gino Heeren; Mark Rinnerthaler; Peter Laun; Phyllis von Seyerl; Sonja Kössler; Harald Klinger; Matthias Hager; Edith Bogengruber; Stefanie Jarolim; Birgit Simon-Nobbe; Christoph Schüller; Didac Carmona-Gutierrez; Lore Breitenbach-Koller; Christoph Mück; Pidder Jansen-Dürr; Alfredo Criollo; Guido Kroemer; Frank Madeo; Michael Breitenbach
The mitochondrial ribosomal protein of the large subunit, Afo1p, determines cellular longevity through mitochondrial back-signaling via TOR1.
Aging 2009;1(7):622-36.
2009: Lorenzo Galluzzi; Klas Blomgren; Guido Kroemer
Mitochondrial membrane permeabilization in neuronal injury.
Nature reviews. Neuroscience 2009;10(7):481-94.
2009: J M Vicencio; C Ortiz; A Criollo; A W E Jones; O Kepp; Lorenzo Galluzzi; Nicholas Joza; I Vitale; E Morselli; M Tailler; M Castedo; M C Maiuri; Jordi Molgo; G Szabadkai; Sergio Lavandero; Guido Kroemer
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.
Cell death and differentiation 2009;16(7):1006-17.
2009: M Uhl; O Kepp; H Jusforgues-Saklani; J-M Vicencio; Guido Kroemer; Matthew L Albert
Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells.
Cell death and differentiation 2009;16(7):991-1005.
2009: Simone Boehrer; L Adès; Nicolas Tajeddine; W K Hofmann; S Kriener; G Bug; O G Ottmann; M Ruthardt; Lorenzo Galluzzi; C Fouassier; M Tailler; K A Olaussen; C Gardin; V Eclache; Stéphane de Botton; S Thepot; Pierre Fenaux; Guido Kroemer
Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome.
Oncogene 2009;28(22):2205-18.
2009: Eugenia Morselli; Lorenzo Galluzzi; Oliver Kepp; Guido Kroemer
Nutlin kills cancer cells via mitochondrial p53.
Cell cycle (Georgetown, Tex.) 2009;8(11):1647-8.
2009: Laura Senovilla; Ilio Vitale; Lorenzo Galluzzi; Sonia Vivet; Nicholas Joza; Amena Ben Younes; Santiago Rello-Varona; Maria Castedo; Guido Kroemer
p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.
Cell cycle (Georgetown, Tex.) 2009;8(9):1380-5.
2009: Frank Madeo; Didac Carmona-Gutierrez; Julia Ring; Sabrina Büttner; Tobias Eisenberg; Guido Kroemer
Caspase-dependent and caspase-independent cell death pathways in yeast.
Biochemical and biophysical research communications 2009;382(2):227-31.
2009: Lorenzo Galluzzi; Eugenia Morselli; Oliver Kepp; Guido Kroemer
Targeting post-mitochondrial effectors of apoptosis for neuroprotection.
Biochimica et biophysica acta 2009;1787(5):402-13.
2009: Yungan Tao; Céline Leteur; Ceyao Yang; Ping Zhang; Maria Castedo; Alain Pierré; Roy M Golsteyn; Jean Bourhis; Guido Kroemer; Eric Deutsch
Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.
Cell cycle (Georgetown, Tex.) 2009;8(8):1196-205.
2009: Santiago Rello-Varona; Ilio Vitale; Oliver Kepp; Laura Senovilla; Mohamed Jemaá; Didier Métivier; Maria Castedo; Guido Kroemer
Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.
Cell cycle (Georgetown, Tex.) 2009;8(7):1030-5.
2009: Oliver Kepp; Antoine Tesniere; Frederic Schlemmer; Mickael Michaud; Laura Senovilla; Laurence Zitvogel; Guido Kroemer
Immunogenic cell death modalities and their impact on cancer treatment.
Apoptosis : an international journal on programmed cell death 2009;14(4):364-75.
2009: Frank Madeo; Guido Kroemer
Intricate links between ER stress and apoptosis.
Molecular cell 2009;33(6):669-70.
2009: Oliver Kepp; Laura Senovilla; Lorenzo Galluzzi; Theocharis Panaretakis; Antoine Tesniere; Frederic Schlemmer; Frank Madeo; Laurence Zitvogel; Guido Kroemer
Viral subversion of immunogenic cell death.
Cell cycle (Georgetown, Tex.) 2009;8(6):860-9.
2009: Theocharis Panaretakis; Oliver Kepp; Ulf Brockmeier; Antoine Tesniere; Ann-Charlotte Bjorklund; Daniel C Chapman; Michael Durchschlag; Nicholas Joza; Gérard Pierron; Peter van Endert; Junying Yuan; Laurence Zitvogel; Frank Madeo; David B Williams; Guido Kroemer
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.
The EMBO journal 2009;28(5):578-90.
2009: J Grosjean-Raillard; M Tailler; L Adès; Jean-Luc PERFETTINI; Claire Fabre; Thorsten Braun; Stéphane de Botton; Pierre Fenaux; Guido Kroemer
ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Oncogene 2009;28(8):1099-109.
2009: Lorenzo Galluzzi; Guido Kroemer
Shigella targets the mitochondrial checkpoint of programmed necrosis.
Cell host & microbe 2009;5(2):107-9.
2009: Frank Madeo; Michael Durchschlag; Oliver Kepp; Theocharis Panaretakis; Laurence Zitvogel; Kai-Uwe Fröhlich; Guido Kroemer
Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals.
Cell cycle (Georgetown, Tex.) 2009;8(4):639-42.
2009: Claire Séror; Syed Qasim RAZA; Fanélie Brottes; Frédéric Subra; Mauro Piacentini; Jean-Luc PERFETTINI; Guido Kroemer
Pro-apoptotic function of checkpoint kinase-2 in syncytia elicited by the HIV-1 envelope.
Cell cycle (Georgetown, Tex.) 2009;8(3):438-42.
2009: Laura Mondragón; Lorenzo Galluzzi; Shahul Mouhamad; Mar Orzáez; José-Miguel Vicencio; Ilio Vitale; Alejandra Moure; Angel Messeguer; Enrique Perez-Paya; Guido Kroemer
A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint.
Apoptosis : an international journal on programmed cell death 2009;14(2):182-90.
2009: Jean-Luc PERFETTINI; Roberta Nardacci; C Séror; Mehdi Bourouba; Frédéric Subra; Laurent Gros; G Manic; Alessandra Amendola; Peggy Masdehors; Filippo Rosselli; David M Ojcius; Christian Auclair; Hugues de Thé; Marie-lise GOUGEON; Mauro Piacentini; Guido Kroemer
The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope.
Cell death and differentiation 2009;16(2):298-311.
2009: Christoph Ruckenstuhl; Sabrina Büttner; Didac Carmona-Gutierrez; Tobias Eisenberg; Guido Kroemer; Stephan J Sigrist; Kai-Uwe Fröhlich; Frank Madeo
The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer.
PloS one 2009;4(2):e4592.
2009: Oliver Kepp; Antoine Tesniere; Laurence Zitvogel; Guido Kroemer
The immunogenicity of tumor cell death.
Current opinion in oncology 2009;21(1):71-6.
2008: Lorenzo Galluzzi; Guido Kroemer
Necroptosis: a specialized pathway of programmed necrosis.
Cell 2008;135(7):1161-3.
2008: Laurence Zitvogel; Guido Kroemer
The dilemma of anticancer therapy: tumor-specific versus immune effects.
Blood 2008;112(12):4364-5.
2008: Guido Kroemer; Beth Levine
Autophagic cell death: the story of a misnomer.
Nature reviews. Molecular cell biology 2008;9(12):1004-10.
2008: Simone Boehrer; Lionel Adès; Lorenzo Galluzzi; Nicolas Tajeddine; Maximilien Tailler; Claude Gardin; Stéphane de Botton; Pierre Fenaux; Guido Kroemer
Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison.
Biochemical pharmacology 2008;76(11):1417-25.
2008: Laurence Zitvogel; Antoine Tesniere; Lionel Apetoh; François Ghiringhelli; Guido Kroemer
[Immunological aspects of anticancer chemotherapy].
Bulletin de l'Académie nationale de médecine 2008;192(7):1469-87; discussion 1487-9.
2008: Ezgi Tasdemir; M Chiara Maiuri; idil orhon; Oliver Kepp; Eugenia Morselli; Alfredo Criollo; Guido Kroemer
p53 represses autophagy in a cell cycle-dependent fashion.
Cell cycle (Georgetown, Tex.) 2008;7(19):3006-11.
2008: Eugenia Morselli; Ezgi Tasdemir; M Chiara Maiuri; Lorenzo Galluzzi; Oliver Kepp; Alfredo Criollo; José Miguel Vicencio; thierry soussi; Guido Kroemer
Mutant p53 protein localized in the cytoplasm inhibits autophagy.
Cell cycle (Georgetown, Tex.) 2008;7(19):3056-61.
2008: Lorenzo Galluzzi; Eugenia Morselli; José Miguel Vicencio; Oliver Kepp; Nicholas Joza; Nicolas Tajeddine; Guido Kroemer
Life, death and burial: multifaceted impact of autophagy.
Biochemical Society transactions 2008;36(Pt 5):786-90.
2008: Nektarios Tavernarakis; A Pasparaki; Ezgi Tasdemir; Maria Chiara Maiuri; Guido Kroemer
The effects of p53 on whole organism longevity are mediated by autophagy.
Autophagy 2008;4(7):870-3.
2008: Laurence Zitvogel; Guido Kroemer
Introduction: the immune response against dying cells.
Current opinion in immunology 2008;20(5):501-3.
2008: Antoine Tesniere; Lionel Apetoh; François Ghiringhelli; Nicholas Joza; Theocharis Panaretakis; Oliver Kepp; Frederic Schlemmer; Laurence Zitvogel; Guido Kroemer
Immunogenic cancer cell death: a key-lock paradigm.
Current opinion in immunology 2008;20(5):504-11.
2008: Jennifer Grosjean-Raillard; Lionel Adès; Simone Boehrer; Maximilien Tailler; Claire Fabre; Thorsten Braun; Stéphane de Botton; Alain Israel; Pierre Fenaux; Guido Kroemer
Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death 2008;13(9):1148-61.
2008: Pierre-Emmanuel Puig; Marie-Noëlle Guilly; André Bouchot; Nathalie Droin; Dominique Cathelin; Florence Bouyer; Laure Favier; François Ghiringhelli; Guido Kroemer; Eric Solary; François Martin; Bruno Chauffert
Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy.
Cell biology international 2008;32(9):1031-43.
2008: Theocharis Panaretakis; Nicholas Joza; Nazanine Modjtahedi; Antoine Tesniere; Ilio Vitale; M Durchschlag; Gian Maria Fimia; O Kepp; Mauro Piacentini; K-U Froehlich; Peter van Endert; Laurence Zitvogel; Frank Madeo; Guido Kroemer
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Cell death and differentiation 2008;15(9):1499-509.
2008: Ezgi Tasdemir; M Chiara Maiuri; Eugenia Morselli; Alfredo Criollo; Marcello D'Amelio; Mojgan Djavaheri-Mergny; Francesco Cecconi; Nektarios Tavernarakis; Guido Kroemer
A dual role of p53 in the control of autophagy.
Autophagy 2008;4(6):810-4.
2008: Claire Fabre; Jennifer Grosjean; Maximilien Tailler; Simone Boehrer; Lionel Adès; Jean-Luc PERFETTINI; Stéphane de Botton; Pierre Fenaux; Guido Kroemer
A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts.
Cell cycle (Georgetown, Tex.) 2008;7(14):2139-45.
2008: Nicolas Tajeddine; Lorenzo Galluzzi; O Kepp; E Hangen; E Morselli; L Senovilla; N Araujo; G Pinna; N Larochette; Naoufal Zamzami; Nazanine Modjtahedi; A Harel-Bellan; Guido Kroemer
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death.
Oncogene 2008;27(30):4221-32.
2008: Ilio Vitale; Laura Senovilla; Lorenzo Galluzzi; Alfredo Criollo; Sonia Vivet; Maria Castedo; Guido Kroemer
Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells.
Cell cycle (Georgetown, Tex.) 2008;7(13):1956-61.
2008: Lorenzo Galluzzi; Eugenia Morselli; Oliver Kepp; Nicolas Tajeddine; Guido Kroemer
Targeting p53 to mitochondria for cancer therapy.
Cell cycle (Georgetown, Tex.) 2008;7(13):1949-55.
2008: Eugenia Morselli; Lorenzo Galluzzi; Guido Kroemer
Mechanisms of p53-mediated mitochondrial membrane permeabilization.
Cell research 2008;18(7):708-10.
2008: Jens Hoffmann; Ilio Vitale; Bernd Buchmann; Lorenzo Galluzzi; Wolfgang Schwede; Laura Senovilla; Werner Skuballa; Sonia Vivet; Rosemarie B Lichtner; José M Vicencio; Theocharis Panaretakis; Gerhard Siemeister; Hermann Lage; Lisa Nanty; Stefanie Hammer; Kevin Mittelstaedt; Sebastian Winsel; Julia Eschenbrenner; Maria Castedo; Carine Demarche; Ulrich Klar; Guido Kroemer
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone.
Cancer research 2008;68(13):5301-8.
2008: Guido Kroemer; A M Tolkovsky; Zahra Zakeri
Elan vital, élan létal: one life but multiple deaths.
Cell death and differentiation 2008;15(7):1089-90.
2008: Hans Zischka; Nathanael Larochette; Florian Hoffmann; Daniela Hamöller; Nora Jägemann; Josef Lichtmannegger; Luise Jennen; Josef Müller-Höcker; Frigga Roggel; Martin Göttlicher; Angelika M Vollmar; Guido Kroemer
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition.
Analytical chemistry 2008;80(13):5051-8.
2008: Beth Levine; Sangita Sinha; Guido Kroemer
Bcl-2 family members: dual regulators of apoptosis and autophagy.
Autophagy 2008;4(5):600-6.
2008: Lorenzo Galluzzi; Nicholas Joza; Ezgi Tasdemir; M Chiara Maiuri; Michael O. Hengartner; John M Abrams; N Tavernarakis; Josef M Penninger; Frank Madeo; Guido Kroemer
No death without life: vital functions of apoptotic effectors.
Cell death and differentiation 2008;15(7):1113-23.
2008: Guido Kroemer; Jacques Pouyssegur
Tumor cell metabolism: cancer's Achilles' heel.
Cancer cell 2008;13(6):472-82.
2008: Laurence Zitvogel; Lionel Apetoh; François Ghiringhelli; Fabrice André; Antoine Tesniere; Guido Kroemer
The anticancer immune response: indispensable for therapeutic success?
The Journal of clinical investigation 2008;118(6):1991-2001.
2008: Lionel Apetoh; Antoine Tesniere; François Ghiringhelli; Guido Kroemer; Laurence Zitvogel
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies.
Cancer research 2008;68(11):4026-30.
2008: Toshio Hisatomi; Toru Nakazawa; Kousuke Noda; Lama Almulki; Shinsuke Miyahara; Shintaro Nakao; Yasuhiro Ito; Haicheng She; Riichiro Kohno; Norman Michaud; Tatsuro Ishibashi; Ali Hafezi-Moghadam; andrew badley; Guido Kroemer; Joan W Miller
HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
The Journal of clinical investigation 2008;118(6):2025-38.
2008: Ezgi Tasdemir; M Chiara Maiuri; Lorenzo Galluzzi; Ilio Vitale; Mojgan Djavaheri-Mergny; Marcello D'Amelio; Alfredo Criollo; Eugenia Morselli; Changlian Zhu; Francis Harper; Ulf Nannmark; Chrysanthi Samara; Paolo Pinton; José Miguel Vicencio; Rosa Carnuccio; Ute M Moll; Frank Madeo; Patrizia Paterlini-Brechot; Rosario Rizzuto; Gyorgy Szabadkai; Gérard Pierron; Klas Blomgren; Nektarios Tavernarakis; Patrice Codogno; Francesco Cecconi; Guido Kroemer
Regulation of autophagy by cytoplasmic p53.
Nature cell biology 2008;10(6):676-87.
2008: Lorenzo Galluzzi; catherine brenner; Eugenia Morselli; Zahia Touat; Guido Kroemer
Viral control of mitochondrial apoptosis.
PLoS pathogens 2008;4(5):e1000018.
2008: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; M Obeid; Grégoire Mignot; Evelyn Ullrich; Guido Kroemer; Laurence Zitvogel
Cancer is not just a disease of a tissue: it is a host disease. How to reactivate host defense against tumors using conventional therapies of cancer?
Annales d'endocrinologie 2008;69(2):151-2.
2008: Eric Solary; Fabrizio Giordanetto; Guido Kroemer
Re-examining the role of cytochrome c in cell death.
Nature genetics 2008;40(4):379-80.
2008: Lionel Apetoh; Grégoire Mignot; Theocharis Panaretakis; Guido Kroemer; Laurence Zitvogel
Immunogenicity of anthracyclines: moving towards more personalized medicine.
Trends in molecular medicine 2008;14(4):141-51.
2008: Sabrina Büttner; Alessandro Bitto; Julia Ring; Manuela Augsten; Piotr Zabrocki; Tobias Eisenberg; Helmut Jungwirth; Sylvia Hutter; Didac Carmona-Gutierrez; Guido Kroemer; Joris Winderickx; Frank Madeo
Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.
The Journal of biological chemistry 2008;283(12):7554-60.
2008: Lorenzo Galluzzi; José Miguel Vicencio; Oliver Kepp; Ezgi Tasdemir; M Chiara Maiuri; Guido Kroemer
To die or not to die: that is the autophagic question.
Current molecular medicine 2008;8(2):78-91.
2008: Simone Boehrer; Lionel Adès; Thorsten Braun; Lorenzo Galluzzi; Jennifer Grosjean; Claire Fabre; Génèviève Le Roux; Claude Gardin; Antoine Martin; Stéphane de Botton; Pierre Fenaux; Guido Kroemer
Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study.
Blood 2008;111(4):2170-80.
2008: Roberta Tufi; Theocharis Panaretakis; Katiuscia Bianchi; Alfredo Criollo; Barbara Fazi; Federica Di Sano; Antoine Tesniere; O Kepp; P Paterlini-Brechot; Laurence Zitvogel; Mauro Piacentini; Gyorgy Szabadkai; Guido Kroemer
Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin.
Cell death and differentiation 2008;15(2):274-82.
2008: Aurélien Deniaud; O Sharaf el dein; E Maillier; Delphine Poncet; Guido Kroemer; Christophe Lemaire; catherine brenner
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis.
Oncogene 2008;27(3):285-99.
2008: Lorenzo Galluzzi; Ilio Vitale; Oliver Kepp; Claire Séror; Emilie Hangen; Jean-Luc PERFETTINI; Nazanine Modjtahedi; Guido Kroemer
Methods to dissect mitochondrial membrane permeabilization in the course of apoptosis.
Methods in enzymology 2008;442():355-74.
2008: Jean-Luc PERFETTINI; Roberta Nardacci; Mehdi Bourouba; Frédéric Subra; Laurent Gros; Claire Séror; Gwenola Manic; Filippo Rosselli; Alessandra Amendola; Peggy Masdehors; Luciana Chessa; Giuseppe Novelli; David M Ojcius; Jan Konrad Siwicki; Magdalena Chechlinska; Christian Auclair; José R Regueiro; Hugues de Thé; Marie-lise GOUGEON; Mauro Piacentini; Guido Kroemer
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia.
PloS one 2008;3(6):e2458.
2008: José Miguel Vicencio; Lorenzo Galluzzi; Nicolas Tajeddine; Carla Ortiz; Alfredo Criollo; Ezgi Tasdemir; Eugenia Morselli; Amena Ben Younes; Maria Chiara Maiuri; Sergio Lavandero; Guido Kroemer
Senescence, apoptosis or autophagy? When a damaged cell must decide its path--a mini-review.
Gerontology 2008;54(2):92-9.
2008: Ezgi Tasdemir; Lorenzo Galluzzi; M Chiara Maiuri; Alfredo Criollo; Ilio Vitale; Emilie Hangen; Nazanine Modjtahedi; Guido Kroemer
Methods for assessing autophagy and autophagic cell death.
Methods in molecular biology (Clifton, N.J.) 2008;445():29-76.
2008: Laurence Zitvogel; Lionel Apetoh; François Ghiringhelli; Guido Kroemer
Immunological aspects of cancer chemotherapy.
Nature reviews. Immunology 2008;8(1):59-73.
2008: Laurence Zitvogel; Guido Kroemer
The immune response against dying tumor cells: avoid disaster, achieve cure.
Cell death and differentiation 2008;15(1):1-2.
2008: Antoine Tesniere; Theocharis Panaretakis; O Kepp; Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel; Guido Kroemer
Molecular characteristics of immunogenic cancer cell death.
Cell death and differentiation 2008;15(1):3-12.
2008: Evelyn Ullrich; Mathieu Bonmort; Grégoire Mignot; Guido Kroemer; Laurence Zitvogel
Tumor stress, cell death and the ensuing immune response.
Cell death and differentiation 2008;15(1):21-8.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Alfredo Criollo; Carla Ortiz; Rosette Lidereau; Christophe Mariette; Nathalie Chaput; Jean-Paul Mira; Suzette Delaloge; Fabrice André; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.
Immunological reviews 2007;220():47-59.
2007: Michel Obeid; Antoine Tesniere; Theocharis Panaretakis; Roberta Tufi; Nick Joza; Peter van Endert; François Ghiringhelli; Lionel Apetoh; Nathalie Chaput; Caroline Flament; Evelyn Ullrich; Stéphane de Botton; Laurence Zitvogel; Guido Kroemer
Ecto-calreticulin in immunogenic chemotherapy.
Immunological reviews 2007;220():22-34.
2007: Yael Zermati; Shahul Mouhamad; Lilli Stergiou; Benjamin Besse; Lorenzo Galluzzi; Simone Boehrer; Anne-Laure Pauleau; Filippo Rosselli; Marcello D'Amelio; Roberto Amendola; Maria Castedo; Michael O. Hengartner; Jean-Charles Soria; Francesco Cecconi; Guido Kroemer
Nonapoptotic role for Apaf-1 in the DNA damage checkpoint.
Molecular cell 2007;28(4):624-37.
2007: J Andrew Pospisilik; Claude Knauf; Nicholas Joza; Paule Benit; Michael Orthofer; Patrice Cani; Ingo Ebersberger; Tomoki Nakashima; Renu Sarao; Gregory Neely; Harald Esterbauer; Andrey Kozlov; C Ronald Kahn; Guido Kroemer; Pierre Rustin; Rémy Burcelin; Josef M Penninger
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Cell 2007;131(3):476-91.
2007: Anne-Laure Pauleau; Nathanael Larochette; F Giordanetto; Sebastian R Scholz; Delphine Poncet; Naoufal Zamzami; Victor S Goldmacher; Guido Kroemer
Structure-function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA.
Oncogene 2007;26(50):7067-80.
2007: Ken A Olaussen; Pierre Fouret; Guido Kroemer
ERCC1-specific immunostaining in non-small-cell lung cancer.
The New England journal of medicine 2007;357(15):1559-61.
2007: Nathalie Chaput; Stéphane de Botton; Michel Obeid; Lionel Apetoh; François Ghiringhelli; Theocharis Panaretakis; Caroline Flament; Laurence Zitvogel; Guido Kroemer
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference.
Journal of molecular medicine (Berlin, Germany) 2007;85(10):1069-76.
2007: Michel Obeid; Theocharis Panaretakis; Nick Joza; Roberta Tufi; Antoine Tesniere; Peter van Endert; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Cell death and differentiation 2007;14(10):1848-50.
2007: Ezgi Tasdemir; M Chiara Maiuri; Nicolas Tajeddine; Ilio Vitale; Alfredo Criollo; José Miguel Vicencio; John A Hickman; Olivier Geneste; Guido Kroemer
Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy.
Cell cycle (Georgetown, Tex.) 2007;6(18):2263-7.
2007: Michel Obeid; Theocharis Panaretakis; Antoine Tesniere; Nick Joza; Roberta Tufi; Lionel Apetoh; François Ghiringhelli; Laurence Zitvogel; Guido Kroemer
Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic.
Cancer research 2007;67(17):7941-4.
2007: Lionel Apetoh; François Ghiringhelli; Antoine Tesniere; Michel Obeid; Carla Ortiz; Alfredo Criollo; Grégoire Mignot; M Chiara Maiuri; Evelyn Ullrich; Patrick Saulnier; Huan Yang; Sebastian Amigorena; Bernhard RYFFEL; Franck J Barrat; Paul Saftig; Francis Levi; Rosette Lidereau; Catherine Nogues; Jean-Paul Mira; Agnès Chompret; Virginie Joulin; Françoise Clavel-Chapelon; Jean Bourhis; Fabrice André; Suzette Delaloge; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Nature medicine 2007;13(9):1050-9.
2007: Changlian Zhu; Xiaoyang Wang; Johanna Deinum; Zhiheng Huang; Jianfeng Gao; Nazanine Modjtahedi; Martha R Neagu; Michael Nilsson; Peter S Eriksson; Henrik Hagberg; Jeremy Luban; Guido Kroemer; Klas Blomgren
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.
The Journal of experimental medicine 2007;204(8):1741-8.
2007: Guido Kroemer
Cancer: defeating the immortal.
Cancer biology & therapy 2007;6(8):1324-8.
2007: Thibault de La Motte Rouge; Lorenzo Galluzzi; Ken A Olaussen; Yael Zermati; Ezgi Tasdemir; Thomas Robert; Hugues Ripoche; Vladimir Lazar; Philippe Dessen; Francis Harper; Gérard Pierron; Guillaume Pinna; Natalia Araujo; Annick Harel-Belan; Jean-Pierre Armand; Tai Wai Wong; Jean-Charles Soria; Guido Kroemer
A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.
Cancer research 2007;67(13):6253-62.
2007: M Chiara Maiuri; Alfredo Criollo; Ezgi Tasdemir; José Miguel Vicencio; Nicolas Tajeddine; John A Hickman; Olivier Geneste; Guido Kroemer
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L).
Autophagy 2007;3(4):374-6.
2007: Lorenzo Galluzzi; M Chiara Maiuri; Ilio Vitale; H Zischka; Maria Castedo; Laurence Zitvogel; Guido Kroemer
Cell death modalities: classification and pathophysiological implications.
Cell death and differentiation 2007;14(7):1237-43.
2007: Alfredo Criollo; José Miguel Vicencio; Ezgi Tasdemir; M Chiara Maiuri; Sergio Lavandero; Guido Kroemer
The inositol trisphosphate receptor in the control of autophagy.
Autophagy 2007;3(4):350-3.
2007: Claire Fabre; Gabrielle Carvalho; Ezgi Tasdemir; Thorsten Braun; L Adès; Jennifer Grosjean; Simone Boehrer; Didier Métivier; Sylvie Souquère; Gérard Pierron; Pierre Fenaux; Guido Kroemer
NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Oncogene 2007;26(28):4071-83.
2007: Thorsten Braun; Gabrielle Carvalho; Jennifer Grosjean; Lionel Ades; Claire Fabre; Simone Boehrer; Najet Debili; Pierre Fenaux; Guido Kroemer
Differentiating megakaryocytes in myelodysplastic syndromes succumb to mitochondrial derangement without caspase activation.
Apoptosis : an international journal on programmed cell death 2007;12(6):1101-8.
2007: M Chiara Maiuri; Gaëtane Le Toumelin; Alfredo Criollo; Jean-Christophe Rain; Fabien Gautier; Philippe Juin; Ezgi Tasdemir; Gérard Pierron; Kostoula Troulinaki; Nektarios Tavernarakis; John A Hickman; Olivier Geneste; Guido Kroemer
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1.
The EMBO journal 2007;26(10):2527-39.
2007: Sabrina Büttner; Didac Carmona-Gutierrez; Ilio Vitale; Maria Castedo; Doris Ruli; Tobias Eisenberg; Guido Kroemer; Frank Madeo
Depletion of endonuclease G selectively kills polyploid cells.
Cell cycle (Georgetown, Tex.) 2007;6(9):1072-6.
2007: Tobias Eisenberg; Sabrina Büttner; Guido Kroemer; Frank Madeo
The mitochondrial pathway in yeast apoptosis.
Apoptosis : an international journal on programmed cell death 2007;12(5):1011-23.
2007: Lorenzo Galluzzi; Naoufal Zamzami; Thibault de La Motte Rouge; Christophe Lemaire; catherine brenner; Guido Kroemer
Methods for the assessment of mitochondrial membrane permeabilization in apoptosis.
Apoptosis : an international journal on programmed cell death 2007;12(5):803-13.
2007: Alfredo Criollo; M Chiara Maiuri; Ezgi Tasdemir; Ilio Vitale; A A Fiebig; D Andrews; Jordi Molgo; J Díaz; Sergio Lavandero; Francis Harper; Gérard Pierron; D di Stefano; Rosario Rizzuto; Gyorgy Szabadkai; Guido Kroemer
Regulation of autophagy by the inositol trisphosphate receptor.
Cell death and differentiation 2007;14(5):1029-39.
2007: Agathe Tarze; Aurélien Deniaud; Morgane Le Bras; E Maillier; D Molle; Nathanael Larochette; Naoufal Zamzami; Gwénaël Jan; Guido Kroemer; catherine brenner
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization.
Oncogene 2007;26(18):2606-20.
2007: Hana Raslova; Audrey Kauffmann; Dalila Sekkaï; Hugues Ripoche; Frédéric Larbret; Thomas Robert; Diana Tronik Le Roux; Guido Kroemer; Najet Debili; Philippe Dessen; Vladimir Lazar; William Vainchenker
Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach.
Blood 2007;109(8):3225-34.
2007: Gabrielle Carvalho; Claire Fabre; Thorsten Braun; Jennifer Grosjean; L Ades; Fabrice Agou; Ezgi Tasdemir; Simone Boehrer; Alain Israel; Michel Véron; Pierre Fenaux; Guido Kroemer
Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Oncogene 2007;26(16):2299-307.
2007: François Ghiringhelli; Lionel Apetoh; Franck Housseau; Guido Kroemer; Laurence Zitvogel
Links between innate and cognate tumor immunity.
Current opinion in immunology 2007;19(2):224-31.
2007: Changlian Zhu; Xiaoyang Wang; Z Huang; Lin Qiu; Falin Xu; N Vahsen; Michael Nilsson; Peter S Eriksson; Henrik Hagberg; C Culmsee; N Plesnila; Guido Kroemer; Klas Blomgren
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.
Cell death and differentiation 2007;14(4):775-84.
2007: Lionel Apetoh; Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Mauro Piacentini; Guido Kroemer; Laurence Zitvogel
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.
Cancer genomics & proteomics 2007;4(2):65-70.
2007: Evelyn Ullrich; Mathieu Bonmort; Grégoire Mignot; Nathalie Chaput; Julien Taieb; Cédric Ménard; Sophie Viaud; Thomas Tursz; Guido Kroemer; Laurence Zitvogel
Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells.
Cancer research 2007;67(3):851-3.
2007: Olivier FERAUD; Najet Debili; Josef M Penninger; Guido Kroemer
Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF.
Cell death and differentiation 2007;14(2):385-7.
2007: Björn Riefke; Dominik Mumberg; Guido Kroemer; Hector Keun; Kirstin Petersen; Thomas Steger-Hartmann
Oncogenes meet metabolism. From deregulated genes to a broader understanding of tumour physiology. Preface.
Ernst Schering Foundation symposium proceedings 2007;(4):V-VII.
2007: Ilio Vitale; Lorenzo Galluzzi; Sonia Vivet; Lisa Nanty; Philippe Dessen; Laura Senovilla; Ken A Olaussen; Vladimir Lazar; Michelle Prudhomme; Roy M Golsteyn; Maria Castedo; Guido Kroemer
Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway.
PloS one 2007;2(12):e1337.
2007: Naoufal Zamzami; Carine Maisse; Didier Métivier; Guido Kroemer
Measurement of membrane permeability and the permeability transition of mitochondria.
Methods in cell biology 2007;80():327-40.
2007: Guido Kroemer; Lorenzo Galluzzi; catherine brenner
Mitochondrial membrane permeabilization in cell death.
Physiological reviews 2007;87(1):99-163.
2007: Michel Obeid; Antoine Tesniere; François Ghiringhelli; Gian Maria Fimia; Lionel Apetoh; Jean-Luc PERFETTINI; Maria Castedo; Grégoire Mignot; Theocharis Panaretakis; Noelia Casares; Didier Métivier; Nathanael Larochette; Peter van Endert; Fabiola Ciccosanti; Mauro Piacentini; Laurence Zitvogel; Guido Kroemer
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
2007: Alfredo Criollo; Lorenzo Galluzzi; M Chiara Maiuri; Ezgi Tasdemir; Sergio Lavandero; Guido Kroemer
Mitochondrial control of cell death induced by hyperosmotic stress.
Apoptosis : an international journal on programmed cell death 2007;12(1):3-18.
2006: P Zhang; Maria Castedo; Y Tao; Dominique Violot; Didier Métivier; Eric Deutsch; Guido Kroemer; Jean Bourhis
Caspase independence of radio-induced cell death.
Oncogene 2006;25(59):7758-70.
2006: Maria Castedo; Arnaud Coquelle; Ilio Vitale; Sonia Vivet; Shahul Mouhamad; Sophie Viaud; Laurence Zitvogel; Guido Kroemer
Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis.
Annals of the New York Academy of Sciences 2006;1090():35-49.
2006: Antoine Tesniere; Laurence Zitvogel; Guido Kroemer
The immune system: taming and unleashing cancer.
Discovery medicine 2006;6(36):211-6.
2006: Arnaud Coquelle; Shahul Mouhamad; Marie O Pequignot; Thorsten Braun; Gabrielle Carvalho; Sonia Vivet; Didier Métivier; Maria Castedo; Guido Kroemer
Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis.
Biochemical pharmacology 2006;72(11):1396-404.
2006: Sabrina Büttner; Tobias Eisenberg; Eva Herker; Didac Carmona-Gutierrez; Guido Kroemer; Frank Madeo
Why yeast cells can undergo apoptosis: death in times of peace, love, and war.
The Journal of cell biology 2006;175(4):521-5.
2006: Carmen Garrido; Mathilde Brunet; Celine Didelot; Yael Zermati; Elise Schmitt; Guido Kroemer
Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties.
Cell cycle (Georgetown, Tex.) 2006;5(22):2592-601.
2006: Laurence Zitvogel; Antoine Tesniere; Guido Kroemer
Cancer despite immunosurveillance: immunoselection and immunosubversion.
Nature reviews. Immunology 2006;6(10):715-27.
2006: Delphine Poncet; Anne-Laure Pauleau; Gyorgy Szabadkai; Angelo Vozza; Sebastian R Scholz; Morgane Le Bras; Jean-Jacques Briere; Abdelali JALIL; Ronan Le Moigne; catherine brenner; Gabriele Hahn; Ilka Wittig; Hermann Schägger; Christophe Lemaire; Katiuscia Bianchi; Sylvie Souquère; Gérard Pierron; Pierre Rustin; Victor S Goldmacher; Rosario Rizzuto; Ferdinando Palmieri; Guido Kroemer
Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA.
The Journal of cell biology 2006;174(7):985-96.
2006: Morgane Le Bras; Annie Borgne-Sanchez; Zahia Touat; Ossama Sharaf El Dein; Aurélien Deniaud; Evelyne Maillier; Gael Lecellier; Dominique Rebouillat; Christophe Lemaire; Guido Kroemer; Etienne Jacotot; catherine brenner
Chemosensitization by knockdown of adenine nucleotide translocase-2.
Cancer research 2006;66(18):9143-52.
2006: Carmen Garrido; L Galluzzi; Mathilde Brunet; Pierre-Emmanuel Puig; Celine Didelot; Guido Kroemer
Mechanisms of cytochrome c release from mitochondria.
Cell death and differentiation 2006;13(9):1423-33.
2006: Lorenzo Galluzzi; Nathanael Larochette; Naoufal Zamzami; Guido Kroemer
Mitochondria as therapeutic targets for cancer chemotherapy.
Oncogene 2006;25(34):4812-30.
2006: Guido Kroemer
Mitochondria in cancer.
Oncogene 2006;25(34):4630-2.
2006: Christophe Massard; Yael Zermati; Anne-Laure Pauleau; Nathanael Larochette; Didier Métivier; Laure Sabatier; Guido Kroemer; Jean-Charles Soria
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
Oncogene 2006;25(33):4505-14.
2006: Maria Castedo; Arnaud Coquelle; Sonia Vivet; Ilio Vitale; Audrey Kauffmann; Philippe Dessen; Marie O Pequignot; Noelia Casares; Alexander Valent; Shahul Mouhamad; Elise Schmitt; Nazanine Modjtahedi; William Vainchenker; Laurence Zitvogel; Vladimir Lazar; Carmen Garrido; Guido Kroemer
Apoptosis regulation in tetraploid cancer cells.
The EMBO journal 2006;25(11):2584-95.
2006: Nazanine Modjtahedi; Fabrizio Giordanetto; Frank Madeo; Guido Kroemer
Apoptosis-inducing factor: vital and lethal.
Trends in cell biology 2006;16(5):264-72.
2006: Thorsten Braun; Gabrielle Carvalho; Claire Fabre; Jennifer Grosjean; Pierre Fenaux; Guido Kroemer
Targeting NF-kappaB in hematologic malignancies.
Cell death and differentiation 2006;13(5):748-58.
2006: Arnaud Coquelle; Shahul Mouhamad; Marie O Pequignot; Thorsten Braun; Gabrielle Carvalho; Sonia Vivet; Didier Métivier; Maria Castedo; Guido Kroemer
Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells.
Cell death and differentiation 2006;13(5):873-5.
2006: Elise Schmitt; Loic Maingret; Pierre-Emmanuel Puig; Anne-Laure Rerole; François Ghiringhelli; Arlette Hammann; Eric Solary; Guido Kroemer; Carmen Garrido
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Cancer research 2006;66(8):4191-7.
2006: Nicola Vahsen; Céline Candé; Pauline Dupaigne; Fabrizio Giordanetto; Romano T Kroemer; Eva Herker; Sebastian R Scholz; Nazanine Modjtahedi; Frank Madeo; Eric Le Cam; Guido Kroemer
Physical interaction of apoptosis-inducing factor with DNA and RNA.
Oncogene 2006;25(12):1763-74.
2006: Emmanuelle N Sabbah; Sabine Druillennec; Nelly Morellet; Serge Bouaziz; Guido Kroemer; Bernard P Roques
Interaction between the HIV-1 protein Vpr and the adenine nucleotide translocator.
Chemical biology & drug design 2006;67(2):145-54.
2006: Julien Taieb; Nathalie Chaput; Cédric Ménard; Lionel Apetoh; Evelyn Ullrich; Mathieu Bonmort; Marie Péquignot; Noelia Casares; Magali Terme; Caroline Flament; Paule Opolon; Yann Lecluse; Didier Métivier; Elena Tomasello; Eric Vivier; François Ghiringhelli; François Martin; David Klatzmann; Thierry Poynard; Thomas Tursz; Graça Raposo; Hideo Yagita; Bernard Ryffel; Guido Kroemer; Laurence Zitvogel
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Thorsten Braun; Gabrielle Carvalho; Arnaud Coquelle; Marie-Catherine Vozenin; Pascale Lepelley; François Hirsch; Jean-Jacques Kiladjian; Vincent Ribrag; Pierre Fenaux; Guido Kroemer
NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome.
Blood 2006;107(3):1156-65.
2005: Noelia Casares; Marie O Pequignot; Antoine Tesniere; François Ghiringhelli; Stéphan Roux; Nathalie Chaput; Elise Schmitt; Ahmed Hamai; Sandra Hervas-Stubbs; Michel Obeid; Frédéric Coutant; Didier Métivier; Evelyne Pichard; Pierre Aucouturier; Gérard Pierron; Carmen Garrido; Laurence Zitvogel; Guido Kroemer
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.
The Journal of experimental medicine 2005;202(12):1691-701.
2005: Nicholas Joza; Gavin Y Oudit; Doris Brown; Paule Bénit; Zamaneh Kassiri; Nicola Vahsen; Loralyn Benoit; Mikin M Patel; Karin Nowikovsky; Anne Vassault; Peter H Backx; Teiji Wada; Guido Kroemer; Pierre Rustin; Josef M Penninger
Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy.
Molecular and cellular biology 2005;25(23):10261-72.
2005: Rosa-Ana Gonzalez-Polo; Gabrielle Carvalho; Thorsten Braun; Didier Decaudin; Claire Fabre; Nathanael Larochette; Jean-Luc PERFETTINI; Mojgan Djavaheri-Mergny; Ibtissam Youlyouz-Marfak; Patrice Codogno; Martine Raphael; Jean Feuillard; Guido Kroemer
PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor.
Oncogene 2005;24(51):7503-13.
2005: Naoufal Zamzami; Nathanael Larochette; Guido Kroemer
Mitochondrial permeability transition in apoptosis and necrosis.
Cell death and differentiation 2005;12 Suppl 2():1478-80.
2005: Guido Kroemer; Wafik S El-Deiry; P Golstein; M E Peter; D Vaux; P Vandenabeele; B Zhivotovsky; M V Blagosklonny; W Malorni; R A Knight; Mauro Piacentini; S Nagata; G Melino
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death.
Cell death and differentiation 2005;12 Suppl 2():1463-7.
2005: Guido Kroemer; Marja Jäättelä
Lysosomes and autophagy in cell death control.
Nature reviews. Cancer 2005;5(11):886-97.
2005: François Ghiringhelli; Pierre-Emmanuel Puig; Stephan Roux; Arnaud Parcellier; Elise Schmitt; Eric Solary; Guido Kroemer; François Martin; Bruno Chauffert; Laurence Zitvogel
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.
The Journal of experimental medicine 2005;202(7):919-29.
2005: Jean-Luc PERFETTINI; Maria Castedo; Thomas Roumier; Karine Andreau; Roberta Nardacci; Mauro Piacentini; Guido Kroemer
Mechanisms of apoptosis induction by the HIV-1 envelope.
Cell death and differentiation 2005;12 Suppl 1():916-23.
2005: Rosa-Ana González-Polo; Marian Mellen; Anne-Laure Pauleau; Abdelali JALIL; Nathanael Larochette; Sylvie Souquère; Eeva-Liisa Eskelinen; Gérard Pierron; Paul Saftig; Guido Kroemer
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death.
Journal of cell science 2005;118(Pt 14):3091-102.
2005: Guido Kroemer; Seamus Martin
Caspase-independent cell death.
Nature medicine 2005;11(7):725-30.
2005: Joel G R Weaver; Agathe Tarze; Tia C Moffat; Morgane Lebras; Aurélien Deniaud; catherine brenner; Gary D Bren; Mario Y Morin; Barbara N Phenix; Li Dong; Susan X Jiang; Valerie L Sim; Bogdan Zurakowski; Jessica Lallier; Heather Hardin; Peter J Wettstein; Rolf P G van Heeswijk; Andre Douen; Romano T Kroemer; Sheng T Hou; Steffany A L Bennett; David H Lynch; Guido Kroemer; andrew badley
Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor.
The Journal of clinical investigation 2005;115(7):1828-38.
2005: Maria Castedo; Jean-Luc PERFETTINI; Mauro Piacentini; Guido Kroemer
p53-A pro-apoptotic signal transducer involved in AIDS.
Biochemical and biophysical research communications 2005;331(3):701-6.
2005: Naoufal Zamzami; Guido Kroemer
p53 in apoptosis control: an introduction.
Biochemical and biophysical research communications 2005;331(3):685-7.
2005: Jean-Luc PERFETTINI; Thomas Roumier; Guido Kroemer
Mitochondrial fusion and fission in the control of apoptosis.
Trends in cell biology 2005;15(4):179-83.
2005: Marian Mellen; Rosa-Ana González-Polo; Noelia Casares; Jean-Luc PERFETTINI; Philippe Dessen; Nathanael Larochette; Didier Métivier; Daniel Meley; Sylvie Souquere; Tamotsu Yoshimori; Gérard Pierron; Patrice Codogno; Guido Kroemer
Inhibition of macroautophagy triggers apoptosis.
Molecular and cellular biology 2005;25(3):1025-40.
2005: Gabrielle Carvalho; Carmen Lefaucheur; Claire Cherbonnier; Didier Métivier; alain Chapel; Marc Pallardy; Marie-Françoise Bourgeade; Bernard Charpentier; François Hirsch; Guido Kroemer
Chemosensitization by erythropoietin through inhibition of the NF-kappaB rescue pathway.
Oncogene 2005;24(5):737-45.
2005: Jean-Luc PERFETTINI; Maria Castedo; Roberta Nardacci; Fabiola Ciccosanti; Marian Mellen; Thomas Roumier; Nathanael Larochette; Mauro Piacentini; Guido Kroemer
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope.
The Journal of experimental medicine 2005;201(2):279-89.
2004: Karine Andreau; Maria Castedo; Jean-Luc PERFETTINI; Thomas Roumier; Evelyne Pichart; Sylvie Souquere; Sonia Vivet; Nathanael Larochette; Guido Kroemer
Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.
The Journal of biological chemistry 2004;279(53):55937-45.
2004: Marian Mellen; Anne-Laure Pauleau; Delphine Poncet; Rosa-Ana Gonzalez-Polo; Naoufal Zamzami; Guido Kroemer
Viral proteins targeting mitochondria: controlling cell death.
Biochimica et biophysica acta 2004;1659(2-3):178-89.
2004: Carmen Garrido; Guido Kroemer
Life's smile, death's grin: vital functions of apoptosis-executing proteins.
Current opinion in cell biology 2004;16(6):639-46.
2004: Nicola Vahsen; Céline Candé; Jean-Jacques Briere; Paule Bénit; Nicholas Joza; Nathanael Larochette; Pier Giorgio Mastroberardino; Marie O Pequignot; Noelia Casares; Vladimir Lazar; Olivier FERAUD; Najet Debili; Silke Wissing; Silvia M Engelhardt; Frank Madeo; Mauro Piacentini; Josef M Penninger; Hermann Schägger; Pierre Rustin; Guido Kroemer
AIF deficiency compromises oxidative phosphorylation.
The EMBO journal 2004;23(23):4679-89.
2004: D Aguirre; P Boya; Dominique Bellet; S Faivre; Frédéric Troalen; J Benard; Patrick Saulnier; Sally Hopkins-Donaldson; U Zangemeister-Wittke; Guido Kroemer; E Raymond
Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma.
Apoptosis : an international journal on programmed cell death 2004;9(6):797-805.
2004: Karine Andreau; Jean-Luc PERFETTINI; Maria Castedo; Didier Métivier; Véronique Scott; Gérard Pierron; Guido Kroemer
Contagious apoptosis facilitated by the HIV-1 envelope: fusion-induced cell-to-cell transmission of a lethal signal.
Journal of cell science 2004;117(Pt 23):5643-53.
2004: Florence Verrier; Aurélien Deniaud; Morgane Lebras; Didier Métivier; Guido Kroemer; Bernard Mignotte; Gwénaël Jan; catherine brenner
Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis.
Oncogene 2004;23(49):8049-64.
2004: Isabelle Gourdier; Laure Crabbe; Karine Andreau; Bernard Pau; Guido Kroemer
Oxaliplatin-induced mitochondrial apoptotic response of colon carcinoma cells does not require nuclear DNA.
Oncogene 2004;23(45):7449-57.
2004: Silke Wissing; Paula Ludovico; Eva Herker; Sabrina Büttner; Silvia M Engelhardt; Thorsten Decker; Alexander Link; Astrid Proksch; fernando Rodrigues; Manuela Corte-Real; Kai-Uwe Fröhlich; Joachim Manns; Céline Candé; Stephan J Sigrist; Guido Kroemer; Frank Madeo
An AIF orthologue regulates apoptosis in yeast.
The Journal of cell biology 2004;166(7):969-74.
2004: Benjamin Besse; Céline Candé; Jean-Philippe Spano; Antoine Martin; David Khayat; Thierry Le Chevalier; Thomas Tursz; Laure Sabatier; Jean-Charles Soria; Guido Kroemer
Nuclear localization of apoptosis protease activating factor-1 predicts survival after tumor resection in early-stage non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5665-9.
2004: Céline Candé; Nicola Vahsen; Didier Métivier; Hélène Tourrière; Karim Chebli; Carmen Garrido; Jamal Tazi; Guido Kroemer
Regulation of cytoplasmic stress granules by apoptosis-inducing factor.
Journal of cell science 2004;117(Pt 19):4461-8.
2004: Aurélien Deniaud; catherine brenner; Guido Kroemer
Mitochondrial membrane permeabilization by HIV-1 Vpr.
Mitochondrion 2004;4(2-3):223-33.
2004: Céline Candé; Nicola Vahsen; Carmen Garrido; Guido Kroemer
Apoptosis-inducing factor (AIF): caspase-independent after all.
Cell death and differentiation 2004;11(6):591-5.
2004: Maria Castedo; Jean-Luc PERFETTINI; Thomas Roumier; Alexander Valent; Hana Raslova; Kenichi Yakushijin; David A Horne; Jean Feunteun; Gilbert Lenoir; René Medema; William Vainchenker; Guido Kroemer
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.
Oncogene 2004;23(25):4362-70.
2004: Maria Castedo; Jean-Luc PERFETTINI; Thomas Roumier; Kenichi Yakushijin; David A Horne; René Medema; Guido Kroemer
The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
Oncogene 2004;23(25):4353-61.
2004: Delphine Poncet; Nathanael Larochette; Anne-Laure Pauleau; Marian Mellen; Abdelali JALIL; Pierre-Francois Cartron; François M Vallette; Céline Schnebelen; Laura M Bartle; Anna Skaletskaya; David Boutolleau; Jean-Claude Martinou; Victor S Goldmacher; Guido Kroemer; Naoufal Zamzami
An anti-apoptotic viral protein that recruits Bax to mitochondria.
The Journal of biological chemistry 2004;279(21):22605-14.
2004: Elise Schmitt; Arnaud Parcellier; François Ghiringhelli; Noelia Casares; Sandeep Gurbuxani; Nathalie M Droin; Ahmed Hamai; Marie O Pequignot; Arlette Hammann; Monique Moutet; Annie Fromentin; Guido Kroemer; Eric Solary; Carmen Garrido
Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.
Cancer research 2004;64(8):2705-11.
2004: Maria Castedo; Jean-Luc PERFETTINI; Thomas Roumier; Karine Andreau; René Medema; Guido Kroemer
Cell death by mitotic catastrophe: a molecular definition.
Oncogene 2004;23(16):2825-37.
2004: Isabelle Cohen; Marian Mellen; L Zhao; Didier Métivier; Karine Andreau; Jean-Luc PERFETTINI; J G Weaver; andrew badley; E W Taylor; Guido Kroemer
Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1.
Apoptosis : an international journal on programmed cell death 2004;9(2):181-92.
2004: Jean-Luc PERFETTINI; Thomas Roumier; Maria Castedo; Nathanael Larochette; Marian Mellen; Brigitte Raynal; Vladimir Lazar; Fabiola Ciccosanti; Roberta Nardacci; Josef M Penninger; Mauro Piacentini; Guido Kroemer
NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope.
The Journal of experimental medicine 2004;199(5):629-40.
2004: Céline Candé; Nicola Vahsen; Ilektra Kouranti; Elise Schmitt; Eric Daugas; Chris Spahr; Jeremy Luban; Romano T Kroemer; Fabrizio Giordanetto; Carmen Garrido; Josef M Penninger; Guido Kroemer
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis.
Oncogene 2004;23(8):1514-21.
2004: lionel tintignac; Valentina Sirri; Marie Pierre Leibovitch; Yann Lécluse; Maria Castedo; Didier Metivier; Guido Kroemer; Serge Leibovitch
Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry.
Molecular and cellular biology 2004;24(4):1809-21.
2004: Maria Castedo; Guido Kroemer
[Mitotic catastrophe: a special case of apoptosis].
Journal de la Société de biologie 2004;198(2):97-103.
2004: Laurence Zitvogel; Noelia Casares; Marie O Péquignot; Nathalie Chaput; Matthew L Albert; Guido Kroemer
Immune response against dying tumor cells.
Advances in immunology 2004;84():131-79.
2004: Naoufal Zamzami; Guido Kroemer
Methods to measure membrane potential and permeability transition in the mitochondria during apoptosis.
Methods in molecular biology (Clifton, N.J.) 2004;282():103-15.
2003: Maria-Isabel Thoulouze; Mireille Lafage; Victor Jose Yuste; Guido Kroemer; Santos A Susin; Nicole Israel; Monique Lafon
Apoptosis inversely correlates with rabies virus neurotropism.
Annals of the New York Academy of Sciences 2003;1010():598-603.
2003: Maria Castedo; Jean-Luc PERFETTINI; Karine Andreau; Thomas Roumier; Mauro Piacentini; Guido Kroemer
Mitochondrial apoptosis induced by the HIV-1 envelope.
Annals of the New York Academy of Sciences 2003;1010():19-28.
2003: Elise Schmitt; Arnaud Parcellier; Sandeep Gurbuxani; Celine Cande; Arlette Hammann; Maria Celia Morales; Clayton R Hunt; David J Dix; Romano T Kroemer; Fabrizio Giordanetto; Marja Jäättelä; Josef M Penninger; Alena Pance; Guido Kroemer; Carmen Garrido
Chemosensitization by a non-apoptogenic heat shock protein 70-binding apoptosis-inducing factor mutant.
Cancer research 2003;63(23):8233-40.
2003: Carmen Garrido; Elise Schmitt; Céline Candé; Nicola Vahsen; Arnaud Parcellier; Guido Kroemer
HSP27 and HSP70: potentially oncogenic apoptosis inhibitors.
Cell cycle (Georgetown, Tex.) 2003;2(6):579-84.
2003: Thomas Roumier; Maria Castedo; Jean-Luc PERFETTINI; Karine Andreau; Didier Métivier; Naoufal Zamzami; Guido Kroemer
Mitochondrion-dependent caspase activation by the HIV-1 envelope.
Biochemical pharmacology 2003;66(8):1321-9.
2003: Sandeep Gurbuxani; Elise Schmitt; Celine Cande; Arnaud Parcellier; Arlette Hammann; Eric Daugas; Ilektra Kouranti; Chris Spahr; Alena Pance; Guido Kroemer; Carmen Garrido
Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.
Oncogene 2003;22(43):6669-78.
2003: Helena L A Vieira; Guido Kroemer
Mitochondria as targets of apoptosis regulation by nitric oxide.
IUBMB life 2003;55(10-11):613-6.
2003: Delphine Poncet; Marian Mellen; Didier Métivier; Naoufal Zamzami; Guido Kroemer
Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization.
Apoptosis : an international journal on programmed cell death 2003;8(5):521-30.
2003: Maria-Isabel Thoulouze; Mireille Lafage; Victor Jose Yuste; Leïla Baloul; Léna Edelman; Guido Kroemer; Nicole Israel; Santos A Susin; Monique Lafon
High level of Bcl-2 counteracts apoptosis mediated by a live rabies virus vaccine strain and induces long-term infection.
Virology 2003;314(2):549-61.
2003: Marian Mellen; María-Celia Morales; Rosa-Ana Gonzalez-Polo; Karine Andreau; Isabelle Gourdier; Jean-Luc PERFETTINI; Nathanael Larochette; Aurélien Deniaud; Fanny Baran-Marszak; Remi Fagard; Jean Feuillard; Aintzane Asumendi; Martine Raphael; Bernard Pau; catherine brenner; Guido Kroemer
The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family.
Oncogene 2003;22(40):6220-30.
2003: Mauro Piacentini; C Evangelisti; Pier Giorgio Mastroberardino; Roberta Nardacci; Guido Kroemer
Does prothymosin-alpha act as molecular switch between apoptosis and autophagy?
Cell death and differentiation 2003;10(9):937-9.
2003: Guido Kroemer
The mitochondrial permeability transition pore complex as a pharmacological target. An introduction.
Current medicinal chemistry 2003;10(16):1469-72.
2003: Changlian Zhu; Lin Qiu; Xiaoyang Wang; Ulrika Hallin; Céline Candé; Guido Kroemer; Henrik Hagberg; Klas Blomgren
Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain.
Journal of neurochemistry 2003;86(2):306-17.
2003: Marian Mellen; Rosa-Ana Gonzalez-Polo; Delphine Poncet; Karine Andreau; Helena L A Vieira; Thomas Roumier; Jean-Luc PERFETTINI; Guido Kroemer
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.
Oncogene 2003;22(25):3927-36.
2003: Marian Mellen; Karine Andreau; Delphine Poncet; Naoufal Zamzami; Jean-Luc PERFETTINI; Didier Metivier; David M Ojcius; Marja Jäättelä; Guido Kroemer
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion.
The Journal of experimental medicine 2003;197(10):1323-34.
2003: Marian Mellen; Thomas Roumier; Karine Andreau; Rosa-Ana Gonzalez-Polo; Naoufal Zamzami; Maria Castedo; Guido Kroemer
Mitochondrion-targeted apoptosis regulators of viral origin.
Biochemical and biophysical research communications 2003;304(3):575-81.
2003: Guido Kroemer
Mitochondrial control of apoptosis: an introduction.
Biochemical and biophysical research communications 2003;304(3):433-5.
2003: catherine brenner; Guido Kroemer
The mitochondriotoxic domain of Vpr determines HIV-1 virulence.
The Journal of clinical investigation 2003;111(10):1455-7.
2003: Marie-lise GOUGEON; Guido Kroemer
Charming to death: caspase-dependent or -independent?
Cell death and differentiation 2003;10(3):390-2.
2003: Naoufal Zamzami; Guido Kroemer
Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?
Current biology : CB 2003;13(2):R71-3.
2003: Anne-Sophie Belzacq; Helena L A Vieira; Florence Verrier; Grégoire Vandecasteele; Isabelle Cohen; Marie-Christine Prévost; Eric Larquet; Fabrizio Pariselli; Patrice X. PETIT; Axel Kahn; Rosario Rizzuto; catherine brenner; Guido Kroemer
Bcl-2 and Bax modulate adenine nucleotide translocase activity.
Cancer research 2003;63(2):541-6.
2003: Hana Raslova; Lydia Roy; Claire VOURC'H; Jean-Pierre Le Couedic; Olivier Brison; Didier Metivier; Jean Feunteun; Guido Kroemer; Najet Debili; William Vainchenker
Megakaryocyte polyploidization is associated with a functional gene amplification.
Blood 2003;101(2):541-4.
2002: Céline Candé; Francesco Cecconi; Philippe Dessen; Guido Kroemer
Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?
Journal of cell science 2002;115(Pt 24):4727-34.
2002: Maria Castedo; Jean-Luc PERFETTINI; Thomas Roumier; Guido Kroemer
Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.
Cell death and differentiation 2002;9(12):1287-93.
2002: Maria Castedo; Jean-Luc PERFETTINI; Guido Kroemer
Mitochondrial apoptosis and the peripheral benzodiazepine receptor: a novel target for viral and pharmacological manipulation.
The Journal of experimental medicine 2002;196(9):1121-5.
2002: Thomas Roumier; Helena L A Vieira; Maria Castedo; Karine F Ferri; Marian Mellen; Karine Andreau; Sabine Druillennec; Nicholas Joza; Josef M Penninger; Bernard P Roques; Guido Kroemer
The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway.
Cell death and differentiation 2002;9(11):1212-9.
2002: Delphine Haouzi; Isabelle Cohen; Helena L A Vieira; Delphine Poncet; Marian Mellen; Maria Castedo; Nathalie Vadrot; Anne-Sophie Belzacq; Daniel Fau; catherine brenner; G Feldmann; Guido Kroemer
Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo.
Apoptosis : an international journal on programmed cell death 2002;7(5):395-405.
2002: Nicolas Larmonier; Claire Billerey; Cédric Rébé; Arnaud Parcellier; Monique Moutet; Annie Fromentin; Guido Kroemer; Carmen Garrido; Eric Solary; François Martin; Bernard Bonnotte
An atypical caspase-independent death pathway for an immunogenic cancer cell line.
Oncogene 2002;21(39):6091-100.
2002: Maria Castedo; Guido Kroemer
The beauty of death.
Trends in cell biology 2002;12(9):446.
2002: Hong Ye; Celine Cande; Nicolas C Stephanou; Sulin Jiang; Sandeep Gurbuxani; Nathanael Larochette; Eric Daugas; Carmen Garrido; Guido Kroemer; Hao Wu
DNA binding is required for the apoptogenic action of apoptosis inducing factor.
Nature structural biology 2002;9(9):680-4.
2002: Stéphane de Botton; Siham Sabri; Eric Daugas; Yael Zermati; Jacques-Emmanuel Guidotti; Olivier Hermine; Guido Kroemer; William Vainchenker; Najet Debili
Platelet formation is the consequence of caspase activation within megakaryocytes.
Blood 2002;100(4):1310-7.
2002: Sean P Cregan; Andre Fortin; Jason G MacLaurin; Steven M Callaghan; Francesco Cecconi; Seong-Woon Yu; Ted M Dawson; Valina Dawson; David Park; Guido Kroemer; ruth slack
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.
The Journal of cell biology 2002;158(3):507-17.
2002: Maria Castedo; Thomas Roumier; Julià Blanco; Karine F Ferri; Jordi Barretina; lionel tintignac; Karine Andreau; Jean-Luc PERFETTINI; Alessandra Amendola; Roberta Nardacci; Philip Leduc; Donald Ingber; Sabine Druillennec; Bernard P Roques; Serge Leibovitch; Montserrat Vilella-Bach; Jie Chen; José A Este; Nazanine Modjtahedi; Mauro Piacentini; Guido Kroemer
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope.
The EMBO journal 2002;21(15):4070-80.
2002: Luigi Ravagnan; Thomas Roumier; Guido Kroemer
Mitochondria, the killer organelles and their weapons.
Journal of cellular physiology 2002;192(2):131-7.
2002: Isabelle Cohen; Maria Castedo; Guido Kroemer
Tantalizing Thanatos: unexpected links in death pathways.
Trends in cell biology 2002;12(7):293-5.
2002: Maria Castedo; Karine F Ferri; Thomas Roumier; Didier Métivier; Naoufal Zamzami; Guido Kroemer
Quantitation of mitochondrial alterations associated with apoptosis.
Journal of immunological methods 2002;265(1-2):39-47.
2002: María J Maté; Miguel Ortiz-Lombardía; Brigitte Boitel; Ahmed Haouz; Diana Tello; Santos A Susin; Josef M Penninger; Guido Kroemer; Pedro Alzari
The crystal structure of the mouse apoptosis-inducing factor AIF.
Nature structural biology 2002;9(6):442-6.
2002: Helena L A Vieira; Marian Mellen; Isabelle Cohen; Chahrazed El Hamel; Delphine Haouzi; Sabine Druillenec; Anne-Sophie Belzacq; catherine brenner; Bernard P Roques; Guido Kroemer
Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).
Oncogene 2002;21(13):1963-77.
2002: Maya Ameyar-Zazoua; Nathanael Larochette; Guillaume Dorothée; Eric Daugas; Hedi Haddada; Vanessa Gouloumet; Didier Métivier; Rodica Stancou; Fathia Mami-Chouaib; Guido Kroemer; Salem Chouaib
Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: role of caspase-8 and mitochondria.
Cancer gene therapy 2002;9(3):219-27.
2002: Nicholas Joza; Guido Kroemer; Josef M Penninger
Genetic analysis of the mammalian cell death machinery.
Trends in genetics : TIG 2002;18(3):142-9.
2002: Céline Candé; Isabelle Cohen; Eric Daugas; Luigi Ravagnan; Nathanael Larochette; Naoufal Zamzami; Guido Kroemer
Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria.
Biochimie 2002;84(2-3):215-22.
2002: Anne-Sophie Belzacq; Helena L A Vieira; Guido Kroemer; catherine brenner
The adenine nucleotide translocator in apoptosis.
Biochimie 2002;84(2-3):167-76.
2002: Guido Kroemer
Introduction: mitochondrial control of apoptosis.
Biochimie 2002;84(2-3):103-4.
2002: Gwénaël Jan; Anne-Sophie Belzacq; Delphine Haouzi; Annette Rouault; Didier Métivier; Guido Kroemer; catherine brenner
Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria.
Cell death and differentiation 2002;9(2):179-88.
2002: P Costantini; Jean-Marie Bruey; Maria Castedo; Didier Métivier; M Loeffler; Santos A Susin; Luigi Ravagnan; Naoufal Zamzami; Carmen Garrido; Guido Kroemer
Pre-processed caspase-9 contained in mitochondria participates in apoptosis.
Cell death and differentiation 2002;9(1):82-8.
2001: Eric Daugas; Céline Candé; Guido Kroemer
Erythrocytes: death of a mummy.
Cell death and differentiation 2001;8(12):1131-3.
2001: Anne-Sophie Belzacq; Chahrazed El Hamel; Helena L A Vieira; Isabelle Cohen; Delphine Haouzi; Didier Métivier; Philippe MARCHETTI; catherine brenner; Guido Kroemer
Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437.
Oncogene 2001;20(52):7579-87.
2001: Karine F Ferri; Guido Kroemer
Organelle-specific initiation of cell death pathways.
Nature cell biology 2001;3(11):E255-63.
2001: Guido Kroemer
Heat shock protein 70 neutralizes apoptosis-inducing factor.
TheScientificWorldJournal 2001;1():590-2.
2001: Maria Castedo; Karine F Ferri; Julià Blanco; Thomas Roumier; Nathanael Larochette; Jordi Barretina; Alessandra Amendola; Roberta Nardacci; Didier Métivier; J A Este; Mauro Piacentini; Guido Kroemer
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation.
The Journal of experimental medicine 2001;194(8):1097-110.
2001: Luigi Ravagnan; Sandeep Gurbuxani; Santos A Susin; Carine Maisse; Eric Daugas; Naoufal Zamzami; T Mak; Marja Jäättelä; Josef M Penninger; Carmen Garrido; Guido Kroemer
Heat-shock protein 70 antagonizes apoptosis-inducing factor.
Nature cell biology 2001;3(9):839-43.
2001: Carmen Garrido; Sandeep Gurbuxani; Luigi Ravagnan; Guido Kroemer
Heat shock proteins: endogenous modulators of apoptotic cell death.
Biochemical and biophysical research communications 2001;286(3):433-42.
2001: Marian Mellen; Bernard P Roques; Guido Kroemer
New EMBO members' review: viral and bacterial proteins regulating apoptosis at the mitochondrial level.
The EMBO journal 2001;20(16):4325-31.
2001: Julián Pardo; P Pérez-Galán; Susana Gamen; Isabel Marzo; Inmaculada Monleón; AA Kaspar; S A Susín; Guido Kroemer; Alan Krensky; Javier Naval; Alberto Anel
A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1222-9.
2001: Helena L A Vieira; Anne-Sophie Belzacq; Delphine Haouzi; F Bernassola; Isabelle Cohen; Etienne Jacotot; Karine F Ferri; Chahrazed El Hamel; Laura M Bartle; G Melino; catherine brenner; Victor S Goldmacher; Guido Kroemer
The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal.
Oncogene 2001;20(32):4305-16.
2001: M D Miramar; P Costantini; Luigi Ravagnan; Lígia M Saraiva; D Haouzi; Greg M Brothers; Josef M Penninger; M Luisa Peleato; Guido Kroemer; Santos A Susin
NADH oxidase activity of mitochondrial apoptosis-inducing factor.
The Journal of biological chemistry 2001;276(19):16391-8.
2001: Guido Kroemer; P Krammer; Mauro Piacentini; G Melino
The European Cell Death Group.
Cell death and differentiation 2001;8(4):438-40.
2001: Nicholas Joza; Santos A Susin; Eric Daugas; William L Stanford; S K Cho; C Y Li; Takehiko Sasaki; Andrew Elia; Hai-Ying M Cheng; Luigi Ravagnan; Karine F Ferri; Naoufal Zamzami; Andrew Wakeham; Raza Hakem; H Yoshida; Young-Yun Kong; Tak W Mak; J C Zúñiga-Pflücker; Guido Kroemer; Josef M Penninger
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.
Nature 2001;410(6828):549-54.
2001: M Loeffler; Eric Daugas; Santos A Susin; Naoufal Zamzami; Didier Metivier; Anna-Liisa Nieminen; Greg M Brothers; Josef M Penninger; Guido Kroemer
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(3):758-67.
2001: Etienne Jacotot; Karine F Ferri; Chahrazed El Hamel; catherine brenner; Sabine Druillennec; J Hoebeke; Pierre Rustin; Didier Métivier; Christine Lenoir; M Geuskens; Helena L A Vieira; M Loeffler; Anne-Sophie Belzacq; Jean-Paul Briand; Naoufal Zamzami; Léna Edelman; ZH Xie; JC Reed; Bernard P Roques; Guido Kroemer
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.
The Journal of experimental medicine 2001;193(4):509-19.
2001: Anne-Sophie Belzacq; Etienne Jacotot; Helena L A Vieira; D Mistro; D J Granville; Z Xie; JC Reed; Guido Kroemer; catherine brenner
Apoptosis induction by the photosensitizer verteporfin: identification of mitochondrial adenine nucleotide translocator as a critical target.
Cancer research 2001;61(4):1260-4.
2001: Karine F Ferri; Guido Kroemer
Mitochondria--the suicide organelles.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(2):111-5.
2001: Naoufal Zamzami; Guido Kroemer
The mitochondrion in apoptosis: how Pandora's box opens.
Nature reviews. Molecular cell biology 2001;2(1):67-71.
2001: Naoufal Zamzami; Carine Maisse; Didier Métivier; Guido Kroemer
Measurement of membrane permeability and permeability transition of mitochondria.
Methods in cell biology 2001;65():147-58.
2000: Naoufal Zamzami; Chahrazed El Hamel; Carine Maisse; catherine brenner; C Muñoz-Pinedo; Anne-Sophie Belzacq; P Costantini; Helena L A Vieira; M Loeffler; Gérard Molle; Guido Kroemer
Bid acts on the permeability transition pore complex to induce apoptosis.
Oncogene 2000;19(54):6342-50.
2000: Helena L A Vieira; Delphine Haouzi; Chahrazed El Hamel; Etienne Jacotot; Anne-Sophie Belzacq; catherine brenner; Guido Kroemer
Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator.
Cell death and differentiation 2000;7(12):1146-54.
2000: Karine F Ferri; Etienne Jacotot; P Leduc; M Geuskens; Donald Ingber; Guido Kroemer
Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size.
Experimental cell research 2000;261(1):119-26.
2000: Karine F Ferri; Etienne Jacotot; M Geuskens; Guido Kroemer
Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex.
Cell death and differentiation 2000;7(11):1137-9.
2000: Karine F Ferri; Etienne Jacotot; Julià Blanco; José A Esté; Naoufal Zamzami; Santos A Susin; Z Xie; Greg M Brothers; JC Reed; Josef M Penninger; Guido Kroemer
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.
The Journal of experimental medicine 2000;192(8):1081-92.
2000: Maria Rita Rippo; Florence Malisan; Luigi Ravagnan; Barbara Tomassini; Ivano Condo; P Costantini; Santos A Susin; Alessandra Rufini; Matilde Todaro; Guido Kroemer; Roberto Testi
GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):2047-54.
2000: Maria Rita Rippo; Florence Malisan; Luigi Ravagnan; Barbara Tomassini; Ivano Condò; P Costantini; Santos A Susin; Alessandra Rufini; Matilde Todaro; Guido Kroemer; Roberto Testi
GD3 ganglioside as an intracellular mediator of apoptosis.
European cytokine network 2000;11(3):487-8.
2000: Jean-Marie Bruey; Cécile Ducasse; Philippe Bonniaud; Luigi Ravagnan; Santos A Susin; Chantal Diaz-Latoud; Sandeep Gurbuxani; André-Patrick Arrigo; Guido Kroemer; Eric Solary; Carmen Garrido
Hsp27 negatively regulates cell death by interacting with cytochrome c.
Nature cell biology 2000;2(9):645-52.
2000: Santos A Susin; Eric Daugas; Luigi Ravagnan; K Samejima; Naoufal Zamzami; M Loeffler; P Costantini; Karine F Ferri; T Irinopoulou; Marie-Christine Prévost; Greg M Brothers; Tak W Mak; Josef M Penninger; W C Earnshaw; Guido Kroemer
Two distinct pathways leading to nuclear apoptosis.
The Journal of experimental medicine 2000;192(4):571-80.
2000: Eric Daugas; Dominique Nochy; Luigi Ravagnan; M Loeffler; Santos A Susin; Naoufal Zamzami; Guido Kroemer
Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis.
FEBS letters 2000;476(3):118-23.
2000: P Costantini; Etienne Jacotot; Didier Decaudin; Guido Kroemer
Mitochondrion as a novel target of anticancer chemotherapy.
Journal of the National Cancer Institute 2000;92(13):1042-53.
2000: Chris Spahr; Santos A Susin; EJ Bures; JH Robinson; Michael T Davis; MD McGinley; Guido Kroemer; Scott D Patterson
Simplification of complex peptide mixtures for proteomic analysis: reversible biotinylation of cysteinyl peptides.
Electrophoresis 2000;21(9):1635-50.
2000: Guido Kroemer; J C Reed
Mitochondrial control of cell death.
Nature medicine 2000;6(5):513-9.
2000: M Loeffler; Guido Kroemer
The mitochondrion in cell death control: certainties and incognita.
Experimental cell research 2000;256(1):19-26.
2000: B Dallaporta; M Pablo; Carine Maisse; Eric Daugas; M Loeffler; Naoufal Zamzami; Guido Kroemer
Proteasome activation as a critical event of thymocyte apoptosis.
Cell death and differentiation 2000;7(4):368-73.
2000: Eric Daugas; Santos A Susin; Naoufal Zamzami; Karine F Ferri; T Irinopoulou; Nathanael Larochette; Marie-Christine Prévost; Brian Leber; D Andrews; Josef M Penninger; Guido Kroemer
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):729-39.
2000: Scott D Patterson; Chris Spahr; Eric Daugas; Santos A Susin; T Irinopoulou; C Koehler; Guido Kroemer
Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition.
Cell death and differentiation 2000;7(2):137-44.
2000: catherine brenner; Hervé Cadiou; Helena L A Vieira; Naoufal Zamzami; I Marzo; Z Xie; Brian Leber; D Andrews; Hervé Duclohier; JC Reed; Guido Kroemer
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator.
Oncogene 2000;19(3):329-36.
2000: P Costantini; Anne-Sophie Belzacq; Helena L A Vieira; Nathanael Larochette; MA de Pablo; Naoufal Zamzami; Santos A Susin; catherine brenner; Guido Kroemer
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis.
Oncogene 2000;19(2):307-14.
2000: Etienne Jacotot; Luigi Ravagnan; M Loeffler; Karine F Ferri; Helena L A Vieira; Naoufal Zamzami; P Costantini; Sabine Druillennec; J Hoebeke; Jean-Paul Briand; T Irinopoulou; Eric Daugas; Santos A Susin; D Cointe; ZH Xie; JC Reed; Bernard P Roques; Guido Kroemer
The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
The Journal of experimental medicine 2000;191(1):33-46.
2000: Karine F Ferri; Etienne Jacotot; Julià Blanco; José A Esté; Guido Kroemer
Mitochondrial control of cell death induced by HIV-1-encoded proteins.
Annals of the New York Academy of Sciences 2000;926():149-64.
2000: catherine brenner; I Marzo; H L de Araujo Vieira; Guido Kroemer
Purification and liposomal reconstitution of permeability transition pore complex.
Methods in enzymology 2000;322():243-52.
2000: Naoufal Zamzami; Didier Métivier; Guido Kroemer
Quantitation of mitochondrial transmembrane potential in cells and in isolated mitochondria.
Methods in enzymology 2000;322():208-13.
2000: Santos A Susin; Nathanael Larochette; M Geuskens; Guido Kroemer
Purification of mitochondria for apoptosis assays.
Methods in enzymology 2000;322():205-8.
2000: Hans Lorenzo; Santos A Susin; Guido Kroemer
Cytofluorometric quantitation of nuclear apoptosis induced in a cell-free system.
Methods in enzymology 2000;322():198-201.
1999: Philippe MARCHETTI; Naoufal Zamzami; Bertrand Joseph; Susanna Schraen-Maschke; Claude Méreau-Richard; P Costantini; Didier Métivier; Santos A Susin; Guido Kroemer; Pierre Formstecher
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.
Cancer research 1999;59(24):6257-66.
1999: Helena L A Vieira; Guido Kroemer
Pathophysiology of mitochondrial cell death control.
Cellular and molecular life sciences : CMLS 1999;56(11-12):971-6.
1999: Nathanael Larochette; Didier Decaudin; Etienne Jacotot; catherine brenner; I Marzo; Santos A Susin; Naoufal Zamzami; Z Xie; J Reed; Guido Kroemer
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
Experimental cell research 1999;249(2):413-21.
1999: Hans Lorenzo; Santos A Susin; Josef M Penninger; Guido Kroemer
Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death.
Cell death and differentiation 1999;6(6):516-24.
1999: B Dallaporta; Philippe MARCHETTI; MA de Pablo; Carine Maisse; H T Duc; Didier Métivier; Naoufal Zamzami; M Geuskens; Guido Kroemer
Plasma membrane potential in thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6534-42.
1999: Luigi Ravagnan; I Marzo; P Costantini; Santos A Susin; Naoufal Zamzami; Patrice X. PETIT; François Hirsch; M Goulbern; Marie-France Poupon; Laurent Miccoli; Z Xie; JC Reed; Guido Kroemer
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore.
Oncogene 1999;18(16):2537-46.
1999: MA de Pablo; Santos A Susin; Etienne Jacotot; Nathanael Larochette; P Costantini; Luigi Ravagnan; Naoufal Zamzami; Guido Kroemer
Palmitate induces apoptosis via a direct effect on mitochondria.
Apoptosis : an international journal on programmed cell death 1999;4(2):81-7.
1999: Santos A Susin; Hans Lorenzo; Naoufal Zamzami; I Marzo; B E Snow; Greg M Brothers; J Mangion; Etienne Jacotot; P Costantini; M Loeffler; Nathanael Larochette; D R Goodlett; R Aebersold; David Siderovski; Josef M Penninger; Guido Kroemer
Molecular characterization of mitochondrial apoptosis-inducing factor.
Nature 1999;397(6718):441-6.
1999: Santos A Susin; Hans Lorenzo; Naoufal Zamzami; I Marzo; catherine brenner; Nathanael Larochette; Marie-Christine Prévost; Pedro Alzari; Guido Kroemer
Mitochondrial release of caspase-2 and -9 during the apoptotic process.
The Journal of experimental medicine 1999;189(2):381-94.
1999: Etienne Jacotot; P Costantini; E Laboureau; Naoufal Zamzami; Santos A Susin; Guido Kroemer
Mitochondrial membrane permeabilization during the apoptotic process.
Annals of the New York Academy of Sciences 1999;887():18-30.
1998: S A Susin; Naoufal Zamzami; Guido Kroemer
Mitochondria as regulators of apoptosis: doubt no more.
Biochimica et biophysica acta 1998;1366(1-2):151-65.
1998: T Hirsch; B Dallaporta; Naoufal Zamzami; Santos A Susin; Luigi Ravagnan; I Marzo; catherine brenner; Guido Kroemer
Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):35-40.
1998: T Hirsch; Didier Decaudin; Santos A Susin; Philippe MARCHETTI; Nathanael Larochette; M Resche-Rigon; Guido Kroemer
PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.
Experimental cell research 1998;241(2):426-34.
1998: B Dallaporta; T Hirsch; Santos A Susin; Naoufal Zamzami; Nathanael Larochette; catherine brenner; I Marzo; Guido Kroemer
Potassium leakage during the apoptotic degradation phase.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5605-15.
1998: I Marzo; Santos A Susin; Patrice X. PETIT; Luigi Ravagnan; catherine brenner; Nathanael Larochette; Naoufal Zamzami; Guido Kroemer
Caspases disrupt mitochondrial membrane barrier function.
FEBS letters 1998;427(2):198-202.
1998: Naoufal Zamzami; catherine brenner; I Marzo; Santos A Susin; Guido Kroemer
Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins.
Oncogene 1998;16(17):2265-82.
1998: I Marzo; catherine brenner; Naoufal Zamzami; Santos A Susin; G Beutner; Dieter Brdiczka; R Rémy; ZH Xie; JC Reed; Guido Kroemer
The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins.
The Journal of experimental medicine 1998;187(8):1261-71.
1998: Didier Métivier; B Dallaporta; Naoufal Zamzami; Nathanael Larochette; Santos A Susin; I Marzo; Guido Kroemer
Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes.
Immunology letters 1998;61(2-3):157-63.
1998: T Hirsch; Santos A Susin; I Marzo; Philippe MARCHETTI; Naoufal Zamzami; Guido Kroemer
Mitochondrial permeability transition in apoptosis and necrosis.
Cell biology and toxicology 1998;14(2):141-5.
1998: Naoufal Zamzami; I Marzo; Santos A Susin; catherine brenner; Nathanael Larochette; Philippe MARCHETTI; J Reed; Reinhard Kofler; Guido Kroemer
The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition.
Oncogene 1998;16(8):1055-63.
1998: I Marzo; catherine brenner; Guido Kroemer
The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1998;52(6):248-51.
1998: Guido Kroemer; B Dallaporta; M Resche-Rigon
The mitochondrial death/life regulator in apoptosis and necrosis.
Annual review of physiology 1998;60():619-42.
1997: Santos A Susin; Naoufal Zamzami; Nathanael Larochette; B Dallaporta; I Marzo; catherine brenner; T Hirsch; Patrice X. PETIT; M Geuskens; Guido Kroemer
A cytofluorometric assay of nuclear apoptosis induced in a cell-free system: application to ceramide-induced apoptosis.
Experimental cell research 1997;236(2):397-403.
1997: T Hirsch; Philippe MARCHETTI; Santos A Susin; B Dallaporta; Naoufal Zamzami; I Marzo; M Geuskens; Guido Kroemer
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.
Oncogene 1997;15(13):1573-81.
1997: Guido Kroemer
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution.
Cell death and differentiation 1997;4(6):443-56.
1997: Santos A Susin; Naoufal Zamzami; Maria Castedo; Eric Daugas; Hong-Gang Wang; Stephan Geley; F Fassy; J C Reed; Guido Kroemer
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis.
The Journal of experimental medicine 1997;186(1):25-37.
1997: S Hortelano; B Dallaporta; Naoufal Zamzami; T Hirsch; Santos A Susin; I Marzo; L Boscá; Guido Kroemer
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.
FEBS letters 1997;410(2-3):373-7.
1997: Guido Kroemer
The proto-oncogene Bcl-2 and its role in regulating apoptosis.
Nature medicine 1997;3(6):614-20.
1997: Antonio Macho; T Hirsch; I Marzo; Philippe MARCHETTI; B Dallaporta; Santos A Susin; Naoufal Zamzami; Guido Kroemer
Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4612-9.
1997: Naoufal Zamzami; T Hirsch; B Dallaporta; Patrice X. PETIT; Guido Kroemer
Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis.
Journal of bioenergetics and biomembranes 1997;29(2):185-93.
1997: T Hirsch; I Marzo; Guido Kroemer
Role of the mitochondrial permeability transition pore in apoptosis.
Bioscience reports 1997;17(1):67-76.
1997: Philippe MARCHETTI; Didier Decaudin; Antonio Macho; Naoufal Zamzami; T Hirsch; Santos A Susin; Guido Kroemer
Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.
European journal of immunology 1997;27(1):289-96.
1997: Didier Decaudin; Stephan Geley; T Hirsch; Maria Castedo; Philippe MARCHETTI; Antonio Macho; Reinhard Kofler; Guido Kroemer
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.
Cancer research 1997;57(1):62-7.
1996: Antonio Macho; Didier Decaudin; Maria Castedo; T Hirsch; Santos A Susin; Naoufal Zamzami; Guido Kroemer
Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.
Cytometry 1996;25(4):333-40.
1996: Philippe MARCHETTI; T Hirsch; Naoufal Zamzami; Maria Castedo; Didier Decaudin; Santos A Susin; B Masse; Guido Kroemer
Mitochondrial permeability transition triggers lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4830-6.
1996: Patrice X. PETIT; Santos A Susin; Naoufal Zamzami; Bernard Mignotte; Guido Kroemer
Mitochondria and programmed cell death: back to the future.
FEBS letters 1996;396(1):7-13.
1996: Santos A Susin; Naoufal Zamzami; Maria Castedo; T Hirsch; Philippe MARCHETTI; Antonio Macho; E Daugas; M Geuskens; Guido Kroemer
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
The Journal of experimental medicine 1996;184(4):1331-41.
1996: Rafael Ramírez; Julia Carracedo; Maria Castedo; Naoufal Zamzami; Guido Kroemer
CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways.
Cellular immunology 1996;172(2):192-9.
1996: Philippe MARCHETTI; Maria Castedo; Santos A Susin; Naoufal Zamzami; T Hirsch; Antonio Macho; A Haeffner; François Hirsch; M Geuskens; Guido Kroemer
Mitochondrial permeability transition is a central coordinating event of apoptosis.
The Journal of experimental medicine 1996;184(3):1155-60.
1996: Maria Castedo; T Hirsch; Santos A Susin; Naoufal Zamzami; Philippe MARCHETTI; Antonio Macho; Guido Kroemer
Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):512-21.
1996: Philippe MARCHETTI; Santos A Susin; Didier Decaudin; Susana Gamen; Maria Castedo; T Hirsch; Naoufal Zamzami; Javier Naval; A Senik; Guido Kroemer
Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.
Cancer research 1996;56(9):2033-8.
1996: Naoufal Zamzami; Philippe MARCHETTI; Maria Castedo; T Hirsch; Santos A Susin; B Masse; Guido Kroemer
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.
FEBS letters 1996;384(1):53-7.
1996: Naoufal Zamzami; Santos A Susin; Philippe MARCHETTI; T Hirsch; I Gómez-Monterrey; Maria Castedo; Guido Kroemer
Mitochondrial control of nuclear apoptosis.
The Journal of experimental medicine 1996;183(4):1533-44.
1996: A González-García; Philippe MARCHETTI; Maria Castedo; Naoufal Zamzami; R Tarazona; Carlos Martínez-A; Guido Kroemer
Polyethylene glycol-modified IL-2 abrogates superantigen-induced anergy without affecting peripheral clonal deletion in vivo.
Clinical immunology and immunopathology 1996;78(3):215-22.
1996: Georges Rawadi; Sergio Roman-Roman; Maria Castedo; V Dutilleul; Santos A Susin; Philippe MARCHETTI; M Geuskens; Guido Kroemer
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):670-8.
1996: Guido Kroemer; F Hirsch; A González-García; C Martínez
Differential involvement of Th1 and Th2 cytokines in autoimmune diseases.
Autoimmunity 1996;24(1):25-33.
1995: Maria Castedo; Antonio Macho; Naoufal Zamzami; T Hirsch; Philippe MARCHETTI; J Uriel; Guido Kroemer
Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo.
European journal of immunology 1995;25(12):3277-84.
1995: Julia Carracedo; Rafael Ramírez; Philippe MARCHETTI; O C Pintado; E Baixeras; C Martínez; Guido Kroemer
Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells.
European journal of immunology 1995;25(11):3094-9.
1995: Antonio Macho; Maria Castedo; Philippe MARCHETTI; J J Aguilar; Didier Decaudin; Naoufal Zamzami; P M Girard; J Uriel; Guido Kroemer
Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers.
Blood 1995;86(7):2481-7.
1995: Guido Kroemer; Patrice X. PETIT; Naoufal Zamzami; Jean-Luc Vayssière; Bernard Mignotte
The biochemistry of programmed cell death.
FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(13):1277-87.
1995: Naoufal Zamzami; Philippe MARCHETTI; Maria Castedo; Didier Decaudin; Antonio Macho; T Hirsch; Santos A Susin; Patrice X. PETIT; Bernard Mignotte; Guido Kroemer
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
The Journal of experimental medicine 1995;182(2):367-77.
1995: Naoufal Zamzami; Philippe MARCHETTI; Maria Castedo; C Zanin; Jean-Luc Vayssière; Patrice X. PETIT; Guido Kroemer
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.
The Journal of experimental medicine 1995;181(5):1661-72.
1995: R Tarazona; A González-García; Naoufal Zamzami; Philippe MARCHETTI; N Frechin; Jose-Angel Gonzalo; M Ruiz-Gayo; N van Rooijen; Carlos Martínez; Guido Kroemer
Chlorpromazine amplifies macrophage-dependent IL-10 production in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):861-70.
1995: Guido Kroemer
The pharmacology of T cell apoptosis.
Advances in immunology 1995;58():211-96.
1995: Guido Kroemer; Naoufal Zamzami; Philippe MARCHETTI; Maria Castedo
Maintenance of the T lymphocyte pool by inhibition of apoptosis: a novel strategy of immunostimulation?
Current topics in microbiology and immunology 1995;200():223-35.
1994: Rafael Ramírez; Julia Carracedo; Naoufal Zamzami; Maria Castedo; Guido Kroemer
Pertussis toxin inhibits activation-induced cell death of human thymocytes, pre-B leukemia cells and monocytes.
The Journal of experimental medicine 1994;180(3):1147-52.
1994: Jose-Angel Gonzalo; R Tarazona; H J Schuurman; F Uytdehaag; G Wick; Carlos Martínez; Guido Kroemer
A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice.
Clinical immunology and immunopathology 1994;71(2):176-82.
1994: Jose-Angel Gonzalo; A González-García; E Baixeras; Naoufal Zamzami; R Tarazona; R Rappuoli; Carlos Martínez; Guido Kroemer; R Tarazona; R Terezone
Pertussis toxin interferes with superantigen-induced deletion of peripheral T cells without affecting T cell activation in vivo. Inhibition of deletion and associated programmed cell death depends on ADP-ribosyltransferase activity.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4291-9.
1994: Jose-Angel Gonzalo; E Baixeras; A González-García; Annie George Chandy; N Van Rooijen; Carlos Martínez; Guido Kroemer
Differential in vivo effects of a superantigen and an antibody targeted to the same T cell receptor. Activation-induced cell death vs passive macrophage-dependent deletion.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(4):1597-608.
1994: Jose-Angel Gonzalo; A González-García; T Kalland; G Hedlung; Carlos Martínez; Guido Kroemer
Linomide inhibits programmed cell death of peripheral T cells in vivo.
European journal of immunology 1994;24(1):48-52.
1993: Georg Wick; Y Hu; S Schwarz; Guido Kroemer
Immunoendocrine communication via the hypothalamo-pituitary-adrenal axis in autoimmune diseases.
Endocrine reviews 1993;14(5):539-63.
1993: Jose-Angel Gonzalo; A González-García; T Kalland; G Hedlund; Carlos Martínez; Guido Kroemer
Linomide, a novel immunomodulator that prevents death in four models of septic shock.
European journal of immunology 1993;23(9):2372-4.
1993: Jose-Angel Gonzalo; A González-García; Carlos Martínez; Guido Kroemer
Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo.
The Journal of experimental medicine 1993;177(5):1239-46.
1993: E Baixeras; Guido Kroemer; E Cuende; C Márquez; Lisardo Boscá; J E Alés Martínez; Carlos Martínez
Signal transduction pathways involved in B-cell induction.
Immunological reviews 1993;132():5-47.
1993: Guido Kroemer; E Cuende; Carlos Martínez
Compartmentalization of the peripheral immune system.
Advances in immunology 1993;53():157-216.
1993: Carlos Martínez; Miguel A R Marcos; I M de Alboran; J M Alonso; Rafael de Cid; Guido Kroemer; A Coutinho
Functional double-negative T cells in the periphery express T cell receptor V beta gene products that cause deletion of single-positive T cells.
European journal of immunology 1993;23(1):250-4.
1993: Jose-Angel Gonzalo; I M de Alborán; Guido Kroemer
Dissociation of autoaggression and self-superantigen reactivity.
Scandinavian journal of immunology 1993;37(1):1-6.
1993: Guido Kroemer; I Moreno de Alborán; Jose-Angel Gonzalo; Carlos Martínez
Immunoregulation by cytokines.
Critical reviews in immunology 1993;13(2):163-91.
1992: C Marquez; C Martinez; Guido Kroemer; L Bosca
Protein kinase C isoenzymes display differential affinity for phorbol esters. Analysis of phorbol ester receptors in B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2560-8.
1992: I M de Alborán; Jose-Angel Gonzalo; Guido Kroemer; Esther Leonardo; Miguel A R Marcos; Carlos Martínez
Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-V beta 8 antibodies.
European journal of immunology 1992;22(8):2153-8.
1992: E Cuende; Guido Kroemer; J M Alonso; D Nemazee; Carlos Martínez; J E Alés-Martínez
Inability of IL-2 and IL-10 to counteract B cell clonal deletion.
Cellular immunology 1992;142(1):94-102.
1992: Jose-Angel Gonzalo; I Moreno de Alborán; J E Alés-Martínez; Carlos Martínez; Guido Kroemer
Expansion and clonal deletion of peripheral T cells induced by bacterial superantigen is independent of the interleukin-2 pathway.
European journal of immunology 1992;22(4):1007-11.
1992: I M De Alborán; J C Gutierrez; Jose-Angel Gonzalo; JOSE LUIS ANDREU SANCHEZ; Miguel A R Marcos; Guido Kroemer; Carlos Martínez
lpr T cells vaccinate against lupus in MRL/lpr mice.
European journal of immunology 1992;22(4):1089-93.
1992: J E Alés-Martinez; David W Scott; R P Phipps; J E Casnellie; Guido Kroemer; Carmen Martinez; L Pezzi
Cross-linking of surface IgM or IgD causes differential biological effects in spite of overlap in tyrosine (de)phosphorylation profile.
European journal of immunology 1992;22(3):845-50.
1992: Jose-Angel Gonzalo; E Cuende; J E Alés-Martínez; Carlos Martínez; Guido Kroemer
Interleukin-2: a possible trigger for autoimmunity.
International archives of allergy and immunology 1992;97(4):251-7.
1992: Guido Kroemer; C Francese; C Martínez
The role of interleukin 2 in the development of autoimmune thyroiditis.
International reviews of immunology 1992;9(2):107-23.
1992: O Williams; Jose-Angel Gonzalo; Carlos Martínez; Guido Kroemer
Coevolution of hosts and microorganisms: an analysis of the involvement of cytokines in host-parasite interactions.
Memórias do Instituto Oswaldo Cruz 1992;87 Suppl 5():11-21.
1991: Guido Kroemer; Carlos Martínez
Cytokines and autoimmune disease.
Clinical immunology and immunopathology 1991;61(3):275-95.
1991: J M Alonso; J Rodriguez; E Viñuela; Guido Kroemer; Carlos Martínez
Highly efficient expression of proteins encoded by recombinant vaccinia virus in lymphocytes.
Scandinavian journal of immunology 1991;34(5):619-26.
1991: A Bárcena; M J Sánchez; J L de la Pompa; María L Toribio; Guido Kroemer; Carlos Martínez-A
Involvement of the interleukin 4 pathway in the generation of functional gamma delta T cells from human pro-T cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7689-93.
1991: Guido Kroemer; Rafael de Cid; I Moreno de Alborán; Jose-Angel Gonzalo; A Iglesias; Carlos Martínez; Jose-Carlos Gutierrez-Ramos
Immunological self-tolerance: an analysis employing cytokines or cytokine receptors encoded by transgenes or a recombinant vaccinia virus.
Immunological reviews 1991;122():173-204.
1991: J L Andreu-Sánchez; I M Moreno de Alborán; Miguel A R Marcos; A Sánchez-Movilla; Carlos Martínez-A; Guido Kroemer
Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice.
The Journal of experimental medicine 1991;173(6):1323-9.
1991: A Bárcena; María L Toribio; Jose-Carlos Gutierrez-Ramos; Guido Kroemer; Carlos Martínez
Interplay between IL-2 and IL-4 in human thymocyte differentiation: antagonism or agonism.
International immunology 1991;3(5):419-25.
1991: Guido Kroemer; JOSE LUIS ANDREU SANCHEZ; Jose-Angel Gonzalo; Jose-Carlos Gutierrez-Ramos; Carlos Martínez
Interleukin-2, autotolerance, and autoimmunity.
Advances in immunology 1991;50():147-235.
1991: Guido Kroemer; A Helmberg; A Bernot; Charles Auffray; Reinhard Kofler
Evolutionary relationship between human and mouse immunoglobulin kappa light chain variable region genes.
Immunogenetics 1991;33(1):42-9.
1990: A Helmberg; R Fässler; Stephan Geley; Karin Jöhrer; Guido Kroemer; Günther Böck; Reinhard Kofler
Glucocorticoid-regulated gene expression in the immune system. Analysis of glucocorticoid-regulated transcripts from the mouse macrophage-like cell line P388D1.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4332-7.
1990: Jose-Carlos Gutierrez-Ramos; JOSE LUIS ANDREU SANCHEZ; I Moreno de Alboran; J Rodriguez; Esther Leonardo; Guido Kroemer; Miguel A R Marcos; Carmen Martinez
Insights into autoimmunity: from classical models to current perspectives.
Immunological reviews 1990;118():73-101.
1990: Hans-Peter Brezinschek; R Faessler; H Klocker; Guido Kroemer; Roswitha Sgonc; Hermann Dietrich; R Jakober; Georg Wick
Analysis of the immune-encodrine feedback loop in the avian system and its alteration in chickens with spontaneous autoimmune thyroiditis.
European journal of immunology 1990;20(10):2155-9.
1990: Guido Kroemer; L N Gastinel; N Neu; C Auffray; Georg Wick
How many genes code for organ-specific autoimmunity?
Autoimmunity 1990;6(3):215-33.
1990: Georg Wick; Hermann Dietrich; Guido Kroemer; Hans-Peter Brezinschek; R Faessler; A H Schuurs
Spontaneous autoimmune thyroiditis: new therapeutic strategies.
Immunology series 1990;52():191-211.
1989: Guido Kroemer; N Neu; T Kuehr; Hermann Dietrich; R Fässler; Karel Hala; Georg Wick
Immunogenetic analysis of spontaneous autoimmune thyroiditis of obese strain chickens.
Clinical immunology and immunopathology 1989;52(2):202-13.
1989: Josef M Penninger; J Klima; Guido Kroemer; Hermann Dietrich; Karel Hala; Georg Wick
Intra-thymic nurse cell lymphocytes can induce a graft-versus-host reaction with high efficiency.
Developmental and comparative immunology 1989;13(4):313-27.
1989: Georg Wick; Hans-Peter Brezinschek; K Hála; Hermann Dietrich; H Wolf; Guido Kroemer
The obese strain of chickens: an animal model with spontaneous autoimmune thyroiditis.
Advances in immunology 1989;47():433-500.
1989: R Strohal; A Helmberg; Guido Kroemer; Reinhard Kofler
Mouse Vk gene classification by nucleic acid sequence similarity.
Immunogenetics 1989;30(6):475-93.
1988: Guido Kroemer; R Faessler; K Hála; G Boeck; Konrad Schauenstein; Hans-Peter Brezinschek; N Neu; Hermann Dietrich; R Jakober; Georg Wick
Genetic analysis of extrathyroidal features of Obese strain (OS) chickens with spontaneous autoimmune thyroiditis.
European journal of immunology 1988;18(10):1499-505.
1988: Guido Kroemer; H Klocker; R Faessler; W Sachsenmaier; Georg Wick
Decreased level of thymidine in the serum of obese strain (OS) chickens with spontaneous autoimmune thyroiditis.
Immunological investigations 1988;17(3):243-56.
1988: Guido Kroemer; R Faessler; Georg Wick
Disturbed immune regulation in spontaneous autoimmune thyroiditis.
Concepts in immunopathology 1988;5():106-29.
1988: Guido Kroemer; G Boeck; Konrad Schauenstein; M Hilchenbach; R Faessler; Georg Wick
T cell hyperproliferation in autoimmunity prone obese strain (OS) chickens is independent of abnormal mitogen binding in vitro and can be demonstrated in vivo.
Developmental and comparative immunology 1988;12(2):363-73.
1987: Guido Kroemer; R Faessler; R Strohal; G Wick; R Kofler
Evidence for a new murine immunoglobulin heavy chain variable region gene family.
Immunological investigations 1987;16(2):107-16.
1987: R Strohal; Guido Kroemer; G Wick; Reinhard Kofler
Complete variable region sequence of a nonfunctionally rearranged kappa light chain transcribed in the nonsecretor P3-X63-Ag8.653 myeloma cell line.
Nucleic acids research 1987;15(6):2771.