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Guido Kroemer

This is a preview profile on BiomedExperts - the first literature-based scientific social network. It brings the right researchers together and allows them to collaborate online. Collexis and Dell provide the BiomedExperts network of +1.5 Million pre-calculated profiles free of charge to researchers worldwide.

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Publications

TOP 3
Moschetti Tommaso; Giuffrè Alessandro; Ardiccioni Chiara; Vallone Beatrice; Modjtahedi Nazanine; Kroemer Guido; Brunori Maurizio
Failure of apoptosis-inducing factor to act as neuroglobin reductase.
Martins Isabelle; Tesniere Antoine; Kepp Oliver; Michaud Mickael; Schlemmer Frederic; Senovilla Laura; Séror Claire; Métivier Didier; Perfettini Jean-Luc; Zitvogel Laurence; Kroemer Guido
Chemotherapy induces ATP release from tumor cells.
Eisenberg Tobias; Knauer Heide; Schauer Alexandra; Büttner Sabrina; Ruckenstuhl Christoph; Carmona-Gutierrez Didac; Ring Julia; Schroeder Sabrina; Magnes Christoph; Antonacci Lucia; Fussi Heike; Deszcz Luiza; Hartl Regina; Schraml Elisabeth; Criollo Alfredo; Megalou Evgenia; Weiskopf Daniela; Laun Peter; Heeren Gino; Breitenbach Michael; Grubeck-Loebenstein Beatrix; Herker Eva; Fahrenkrog Birthe; Fröhlich Kai-Uwe; Sinner Frank; Tavernarakis Nektarios; Minois Nadege; Kroemer Guido; Madeo Frank
Induction of autophagy by spermidine promotes longevity.

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All Publications

2009: Moschetti Tommaso; Giuffrè Alessandro; Ardiccioni Chiara; Vallone Beatrice; Modjtahedi Nazanine; Kroemer Guido; Brunori Maurizio
Failure of apoptosis-inducing factor to act as neuroglobin reductase.
Biochemical and biophysical research communications 2009;390(1):121-4.
2009: Martins Isabelle; Tesniere Antoine; Kepp Oliver; Michaud Mickael; Schlemmer Frederic; Senovilla Laura; Séror Claire; Métivier Didier; Perfettini Jean-Luc; Zitvogel Laurence; Kroemer Guido
Chemotherapy induces ATP release from tumor cells.
Cell cycle (Georgetown, Tex.) 2009;8(22):3723-8.
2009: Eisenberg Tobias; Knauer Heide; Schauer Alexandra; Büttner Sabrina; Ruckenstuhl Christoph; Carmona-Gutierrez Didac; Ring Julia; Schroeder Sabrina; Magnes Christoph; Antonacci Lucia; Fussi Heike; Deszcz Luiza; Hartl Regina; Schraml Elisabeth; Criollo Alfredo; Megalou Evgenia; Weiskopf Daniela; Laun Peter; Heeren Gino; Breitenbach Michael; Grubeck-Loebenstein Beatrix; Herker Eva; Fahrenkrog Birthe; Fröhlich Kai-Uwe; Sinner Frank; Tavernarakis Nektarios; Minois Nadege; Kroemer Guido; Madeo Frank
Induction of autophagy by spermidine promotes longevity.
Nature cell biology 2009;11(11):1305-14.
2009: Galluzzi Lorenzo; Giordanetto Fabrizio; Kroemer Guido
Targeting HSP70 for cancer therapy.
Molecular cell 2009;36(2):176-7.
2009: Madeo Frank; Eisenberg Tobias; Kroemer Guido
Autophagy for the avoidance of neurodegeneration.
Genes & development 2009;23(19):2253-9.
2009: Tao Yungan; Leteur Céline; Calderaro Julien; Girdler Fiona; Zhang Ping; Frascogna Valérie; Varna Mariana; Opolon Paule; Castedo Maria; Bourhis Jean; Kroemer Guido; Deutsch Eric
The aurora B kinase inhibitor AZD1152 sensitizes cancer cells to fractionated irradiation and induces mitotic catastrophe.
Cell cycle (Georgetown, Tex.) 2009;8(19):3172-81.
2009: Galluzzi Lorenzo; Kepp Oliver; Kroemer Guido
RIP kinases initiate programmed necrosis.
Journal of molecular cell biology 2009;1(1):8-10.
2009: Locher Clara; Rusakiewicz Sylvie; Tesnière Antoine; Ghiringhelli François; Apetoh Lionel; Kroemer Guido; Zitvogel Laurence
Witch hunt against tumor cells enhanced by dendritic cells.
Annals of the New York Academy of Sciences 2009;1174():51-60.
2009: Morselli Eugenia; Galluzzi Lorenzo; Kepp Oliver; Vicencio José-Miguel; Criollo Alfredo; Maiuri Maria Chiara; Kroemer Guido
Anti- and pro-tumor functions of autophagy.
Biochimica et biophysica acta 2009;1793(9):1524-32.
2009: Joza Nicholas; Pospisilik J Andrew; Hangen Emilie; Hanada Toshikatsu; Modjtahedi Nazanine; Penninger Josef M; Kroemer Guido
AIF: not just an apoptosis-inducing factor.
Annals of the New York Academy of Sciences 2009;1171():2-11.
2009: Terme Magali; Mignot Grégoire; Ullrich Evelyn; Bonmort Mathieu; Minard-Colin Véronique; Jacquet Alexandra; Schultze Joachim L; Kroemer Guido; Leclerc Claude; Chaput Nathalie; Zitvogel Laurence
The dendritic cell-like functions of IFN-producing killer dendritic cells reside in the CD11b+ subset and are licensed by tumor cells.
Cancer research 2009;69(16):6590-7.
2009: Criollo Alfredo; Dessen Philippe; Kroemer Guido
DRAM: a phylogenetically ancient regulator of autophagy.
Cell cycle (Georgetown, Tex.) 2009;8(15):2319-20.
2009: Zitvogel Laurence; Kroemer Guido
Anticancer immunochemotherapy using adjuvants with direct cytotoxic effects.
The Journal of clinical investigation 2009;119(8):2127-30.
2009: Galluzzi Lorenzo; Blomgren Klas; Kroemer Guido
Mitochondrial membrane permeabilization in neuronal injury.
Nature reviews. Neuroscience 2009;10(7):481-94.
2009: Vicencio J M; Ortiz C; Criollo A; Jones A W E; Kepp O; Galluzzi L; Joza N; Vitale I; Morselli E; Tailler M; Castedo M; Maiuri M C; Molgó J; Szabadkai G; Lavandero S; Kroemer G
The inositol 1,4,5-trisphosphate receptor regulates autophagy through its interaction with Beclin 1.
Cell death and differentiation 2009;16(7):1006-17.
2009: Uhl M; Kepp O; Jusforgues-Saklani H; Vicencio J-M; Kroemer G; Albert M L
Autophagy within the antigen donor cell facilitates efficient antigen cross-priming of virus-specific CD8+ T cells.
Cell death and differentiation 2009;16(7):991-1005.
2009: Morselli Eugenia; Galluzzi Lorenzo; Kepp Oliver; Kroemer Guido
Nutlin kills cancer cells via mitochondrial p53.
Cell cycle (Georgetown, Tex.) 2009;8(11):1647-8.
2009: Boehrer S; Adès L; Tajeddine N; Hofmann W K; Kriener S; Bug G; Ottmann O G; Ruthardt M; Galluzzi L; Fouassier C; Tailler M; Olaussen K A; Gardin C; Eclache V; de Botton S; Thepot S; Fenaux P; Kroemer G
Suppression of the DNA damage response in acute myeloid leukemia versus myelodysplastic syndrome.
Oncogene 2009;28(22):2205-18.
2009: Senovilla Laura; Vitale Ilio; Galluzzi Lorenzo; Vivet Sonia; Joza Nicholas; Younes Amena Ben; Rello-Varona Santiago; Castedo Maria; Kroemer Guido
p53 represses the polyploidization of primary mammary epithelial cells by activating apoptosis.
Cell cycle (Georgetown, Tex.) 2009;8(9):1380-5.
2009: Madeo Frank; Carmona-Gutierrez Didac; Ring Julia; Büttner Sabrina; Eisenberg Tobias; Kroemer Guido
Caspase-dependent and caspase-independent cell death pathways in yeast.
Biochemical and biophysical research communications 2009;382(2):227-31.
2009: Galluzzi Lorenzo; Morselli Eugenia; Kepp Oliver; Kroemer Guido
Targeting post-mitochondrial effectors of apoptosis for neuroprotection.
Biochimica et biophysica acta 2009;1787(5):402-13.
2009: Tao Yungan; Leteur Céline; Yang Ceyao; Zhang Ping; Castedo Maria; Pierré Alain; Golsteyn Roy M; Bourhis Jean; Kroemer Guido; Deutsch Eric
Radiosensitization by Chir-124, a selective CHK1 inhibitor: effects of p53 and cell cycle checkpoints.
Cell cycle (Georgetown, Tex.) 2009;8(8):1196-205.
2009: Rello-Varona Santiago; Vitale Ilio; Kepp Oliver; Senovilla Laura; Jemaá Mohamed; Métivier Didier; Castedo Maria; Kroemer Guido
Preferential killing of tetraploid tumor cells by targeting the mitotic kinesin Eg5.
Cell cycle (Georgetown, Tex.) 2009;8(7):1030-5.
2009: Kepp Oliver; Tesniere Antoine; Schlemmer Frederic; Michaud Mickael; Senovilla Laura; Zitvogel Laurence; Kroemer Guido
Immunogenic cell death modalities and their impact on cancer treatment.
Apoptosis : an international journal on programmed cell death 2009;14(4):364-75.
2009: Madeo Frank; Kroemer Guido
Intricate links between ER stress and apoptosis.
Molecular cell 2009;33(6):669-70.
2009: Kepp Oliver; Senovilla Laura; Galluzzi Lorenzo; Panaretakis Theocharis; Tesniere Antoine; Schlemmer Frederic; Madeo Frank; Zitvogel Laurence; Kroemer Guido
Viral subversion of immunogenic cell death.
Cell cycle (Georgetown, Tex.) 2009;8(6):860-9.
2009: Panaretakis Theocharis; Kepp Oliver; Brockmeier Ulf; Tesniere Antoine; Bjorklund Ann-Charlotte; Chapman Daniel C; Durchschlag Michael; Joza Nicholas; Pierron Gérard; van Endert Peter; Yuan Junying; Zitvogel Laurence; Madeo Frank; Williams David B; Kroemer Guido
Mechanisms of pre-apoptotic calreticulin exposure in immunogenic cell death.
The EMBO journal 2009;28(5):578-90.
2009: Galluzzi Lorenzo; Kroemer Guido
Shigella targets the mitochondrial checkpoint of programmed necrosis.
Cell host & microbe 2009;5(2):107-9.
2009: Madeo Frank; Durchschlag Michael; Kepp Oliver; Panaretakis Theocharis; Zitvogel Laurence; Fröhlich Kai-Uwe; Kroemer Guido
Phylogenetic conservation of the preapoptotic calreticulin exposure pathway from yeast to mammals.
Cell cycle (Georgetown, Tex.) 2009;8(4):639-42.
2009: Séror Claire; Raza Syed Qasim; Brottes Fanélie; Subra Frédéric; Piacentini Mauro; Perfettini Jean-Luc; Kroemer Guido
Pro-apoptotic function of checkpoint kinase-2 in syncytia elicited by the HIV-1 envelope.
Cell cycle (Georgetown, Tex.) 2009;8(3):438-42.
2009: Mondragón Laura; Galluzzi Lorenzo; Mouhamad Shahul; Orzáez Mar; Vicencio José-Miguel; Vitale Ilio; Moure Alejandra; Messeguer Angel; Perez-Paya Enrique; Kroemer Guido
A chemical inhibitor of Apaf-1 exerts mitochondrioprotective functions and interferes with the intra-S-phase DNA damage checkpoint.
Apoptosis : an international journal on programmed cell death 2009;14(2):182-90.
2009: Grosjean-Raillard J; Tailler M; Adès L; Perfettini J-L; Fabre C; Braun T; De Botton S; Fenaux P; Kroemer G
ATM mediates constitutive NF-kappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Oncogene 2009;28(8):1099-109.
2009: Perfettini J-L; Nardacci R; Séror C; Bourouba M; Subra F; Gros L; Manic G; Amendola A; Masdehors P; Rosselli F; Ojcius D M; Auclair C; de Thé H; Gougeon M-L; Piacentini M; Kroemer G
The tumor suppressor protein PML controls apoptosis induced by the HIV-1 envelope.
Cell death and differentiation 2009;16(2):298-311.
2009: Kepp Oliver; Tesniere Antoine; Zitvogel Laurence; Kroemer Guido
The immunogenicity of tumor cell death.
Current opinion in oncology 2009;21(1):71-6.
2009: Ruckenstuhl Christoph; Büttner Sabrina; Carmona-Gutierrez Didac; Eisenberg Tobias; Kroemer Guido; Sigrist Stephan J; Fröhlich Kai-Uwe; Madeo Frank
The Warburg effect suppresses oxidative stress induced apoptosis in a yeast model for cancer.
PloS one 2009;4(2):e4592.
2008: Galluzzi Lorenzo; Kroemer Guido
Necroptosis: a specialized pathway of programmed necrosis.
Cell 2008;135(7):1161-3.
2008: Zitvogel Laurence; Kroemer Guido
The dilemma of anticancer therapy: tumor-specific versus immune effects.
Blood 2008;112(12):4364-5.
2008: Kroemer Guido; Levine Beth
Autophagic cell death: the story of a misnomer.
Nature reviews. Molecular cell biology 2008;9(12):1004-10.
2008: Boehrer Simone; Adès Lionel; Galluzzi Lorenzo; Tajeddine Nicolas; Tailler Maximilien; Gardin Claude; de Botton Stéphane; Fenaux Pierre; Kroemer Guido
Erlotinib and gefitinib for the treatment of myelodysplastic syndrome and acute myeloid leukemia: a preclinical comparison.
Biochemical pharmacology 2008;76(11):1417-25.
2008: Zitvogel Laurence; Tesniere Antoine; Apetoh Lionel; Ghiringhelli François; Kroemer Guido
[Immunological aspects of anticancer chemotherapy]
Bulletin de l'Académie nationale de médecine 2008;192(7):1469-87; discussion 1487-9.
2008: Tasdemir Ezgi; Maiuri Maria Chiara; Orhon Idil; Kepp Oliver; Morselli Eugenia; Criollo Alfredo; Kroemer Guido
p53 represses autophagy in a cell cycle-dependent fashion.
Cell cycle (Georgetown, Tex.) 2008;7(19):3006-11.
2008: Morselli Eugenia; Tasdemir Ezgi; Maiuri Maria Chiara; Galluzzi Lorenzo; Kepp Oliver; Criollo Alfredo; Vicencio José Miguel; Soussi Thierry; Kroemer Guido
Mutant p53 protein localized in the cytoplasm inhibits autophagy.
Cell cycle (Georgetown, Tex.) 2008;7(19):3056-61.
2008: Galluzzi Lorenzo; Morselli Eugenia; Vicencio José Miguel; Kepp Oliver; Joza Nicholas; Tajeddine Nicolas; Kroemer Guido
Life, death and burial: multifaceted impact of autophagy.
Biochemical Society transactions 2008;36(Pt 5):786-90.
2008: Tavernarakis Nektarios; Pasparaki Angela; Tasdemir Ezgi; Maiuri Maria Chiara; Kroemer Guido
The effects of p53 on whole organism longevity are mediated by autophagy.
Autophagy 2008;4(7):870-3.
2008: Zitvogel Laurence; Kroemer Guido
Introduction: the immune response against dying cells.
Current opinion in immunology 2008;20(5):501-3.
2008: Tesniere Antoine; Apetoh Lionel; Ghiringhelli Francois; Joza Nicholas; Panaretakis Theocharis; Kepp Oliver; Schlemmer Frederic; Zitvogel Laurence; Kroemer Guido
Immunogenic cancer cell death: a key-lock paradigm.
Current opinion in immunology 2008;20(5):504-11.
2008: Grosjean-Raillard Jennifer; Adès Lionel; Boehrer Simone; Tailler Maximilien; Fabre Claire; Braun Thorsten; De Botton Stéphane; Israel Alain; Fenaux Pierre; Kroemer Guido
Flt3 receptor inhibition reduces constitutive NFkappaB activation in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Apoptosis : an international journal on programmed cell death 2008;13(9):1148-61.
2008: Puig Pierre-Emmanuel; Guilly Marie-Noëlle; Bouchot André; Droin Nathalie; Cathelin Dominique; Bouyer Florence; Favier Laure; Ghiringhelli François; Kroemer Guido; Solary Eric; Martin François; Chauffert Bruno
Tumor cells can escape DNA-damaging cisplatin through DNA endoreduplication and reversible polyploidy.
Cell biology international 2008;32(9):1031-43.
2008: Panaretakis T; Joza N; Modjtahedi N; Tesniere A; Vitale I; Durchschlag M; Fimia G M; Kepp O; Piacentini M; Froehlich K-U; van Endert P; Zitvogel L; Madeo F; Kroemer G
The co-translocation of ERp57 and calreticulin determines the immunogenicity of cell death.
Cell death and differentiation 2008;15(9):1499-509.
2008: Tasdemir Ezgi; Chiara Maiuri M; Morselli Eugenia; Criollo Alfredo; D'Amelio Marcello; Djavaheri-Mergny Mojgan; Cecconi Francesco; Tavernarakis Nektarios; Kroemer Guido
A dual role of p53 in the control of autophagy.
Autophagy 2008;4(6):810-4.
2008: Vitale Ilio; Senovilla Laura; Galluzzi Lorenzo; Criollo Alfredo; Vivet Sonia; Castedo Maria; Kroemer Guido
Chk1 inhibition activates p53 through p38 MAPK in tetraploid cancer cells.
Cell cycle (Georgetown, Tex.) 2008;7(13):1956-61.
2008: Galluzzi Lorenzo; Morselli Eugenia; Kepp Oliver; Tajeddine Nicolas; Kroemer Guido
Targeting p53 to mitochondria for cancer therapy.
Cell cycle (Georgetown, Tex.) 2008;7(13):1949-55.
2008: Fabre Claire; Grosjean Jennifer; Tailler Maximilien; Boehrer Simone; Adès Lionel; Perfettini Jean-Luc; de Botton Stéphane; Fenaux Pierre; Kroemer Guido
A novel effect of DNA methyltransferase and histone deacetylase inhibitors: NFkappaB inhibition in malignant myeloblasts.
Cell cycle (Georgetown, Tex.) 2008;7(14):2139-45.
2008: Morselli Eugenia; Galluzzi Lorenzo; Kroemer Guido
Mechanisms of p53-mediated mitochondrial membrane permeabilization.
Cell research 2008;18(7):708-10.
2008: Hoffmann Jens; Vitale Ilio; Buchmann Bernd; Galluzzi Lorenzo; Schwede Wolfgang; Senovilla Laura; Skuballa Werner; Vivet Sonia; Lichtner Rosemarie B; Vicencio José M; Panaretakis Theocharis; Siemeister Gerhard; Lage Hermann; Nanty Lisa; Hammer Stefanie; Mittelstaedt Kevin; Winsel Sebastian; Eschenbrenner Julia; Castedo Maria; Demarche Carine; Klar Ulrich; Kroemer Guido
Improved cellular pharmacokinetics and pharmacodynamics underlie the wide anticancer activity of sagopilone.
Cancer research 2008;68(13):5301-8.
2008: Kroemer G; Tolkovsky A M; Zakeri Z
Elan vital, élan létal: one life but multiple deaths.
Cell death and differentiation 2008;15(7):1089-90.
2008: Zischka Hans; Larochette Nathanael; Hoffmann Florian; Hamöller Daniela; Jägemann Nora; Lichtmannegger Josef; Jennen Luise; Müller-Höcker Josef; Roggel Frigga; Göttlicher Martin; Vollmar Angelika M; Kroemer Guido
Electrophoretic analysis of the mitochondrial outer membrane rupture induced by permeability transition.
Analytical chemistry 2008;80(13):5051-8.
2008: Levine Beth; Sinha Sangita; Kroemer Guido
Bcl-2 family members: dual regulators of apoptosis and autophagy.
Autophagy 2008;4(5):600-6.
2008: Tajeddine N; Galluzzi L; Kepp O; Hangen E; Morselli E; Senovilla L; Araujo N; Pinna G; Larochette N; Zamzami N; Modjtahedi N; Harel-Bellan A; Kroemer G
Hierarchical involvement of Bak, VDAC1 and Bax in cisplatin-induced cell death.
Oncogene 2008;27(30):4221-32.
2008: Galluzzi L; Joza N; Tasdemir E; Maiuri M C; Hengartner M; Abrams J M; Tavernarakis N; Penninger J; Madeo F; Kroemer G
No death without life: vital functions of apoptotic effectors.
Cell death and differentiation 2008;15(7):1113-23.
2008: Kroemer Guido; Pouyssegur Jacques
Tumor cell metabolism: cancer's Achilles' heel.
Cancer cell 2008;13(6):472-82.
2008: Zitvogel Laurence; Apetoh Lionel; Ghiringhelli François; André Fabrice; Tesniere Antoine; Kroemer Guido
The anticancer immune response: indispensable for therapeutic success?
The Journal of clinical investigation 2008;118(6):1991-2001.
2008: Apetoh Lionel; Tesniere Antoine; Ghiringhelli François; Kroemer Guido; Zitvogel Laurence
Molecular interactions between dying tumor cells and the innate immune system determine the efficacy of conventional anticancer therapies.
Cancer research 2008;68(11):4026-30.
2008: Hisatomi Toshio; Nakazawa Toru; Noda Kousuke; Almulki Lama; Miyahara Shinsuke; Nakao Shintaro; Ito Yasuhiro; She Haicheng; Kohno Riichiro; Michaud Norman; Ishibashi Tatsuro; Hafezi-Moghadam Ali; Badley Andrew D; Kroemer Guido; Miller Joan W
HIV protease inhibitors provide neuroprotection through inhibition of mitochondrial apoptosis in mice.
The Journal of clinical investigation 2008;118(6):2025-38.
2008: Tasdemir Ezgi; Maiuri M Chiara; Galluzzi Lorenzo; Vitale Ilio; Djavaheri-Mergny Mojgan; D'Amelio Marcello; Criollo Alfredo; Morselli Eugenia; Zhu Changlian; Harper Francis; Nannmark Ulf; Samara Chrysanthi; Pinton Paolo; Vicencio José Miguel; Carnuccio Rosa; Moll Ute M; Madeo Frank; Paterlini-Brechot Patrizia; Rizzuto Rosario; Szabadkai Gyorgy; Pierron Gérard; Blomgren Klas; Tavernarakis Nektarios; Codogno Patrice; Cecconi Francesco; Kroemer Guido
Regulation of autophagy by cytoplasmic p53.
Nature cell biology 2008;10(6):676-87.
2008: Galluzzi Lorenzo; Brenner Catherine; Morselli Eugenia; Touat Zahia; Kroemer Guido
Viral control of mitochondrial apoptosis.
PLoS pathogens 2008;4(5):e1000018.
2008: Apetoh L; Ghiringhelli F; Tesniere A; Obeid M; Mignot G; Ullrich E; Kroemer G; Zitvogel L
Cancer is not just a disease of a tissue: it is a host disease. How to reactivate host defense against tumors using conventional therapies of cancer?
Annales d'endocrinologie 2008;69(2):151-2.
2008: Solary Eric; Giordanetto Fabrizio; Kroemer Guido
Re-examining the role of cytochrome c in cell death.
Nature genetics 2008;40(4):379-80.
2008: Apetoh Lionel; Mignot Grégoire; Panaretakis Theocharis; Kroemer Guido; Zitvogel Laurence
Immunogenicity of anthracyclines: moving towards more personalized medicine.
Trends in molecular medicine 2008;14(4):141-51.
2008: Galluzzi Lorenzo; Vicencio José Miguel; Kepp Oliver; Tasdemir Ezgi; Maiuri Maria Chiara; Kroemer Guido
To die or not to die: that is the autophagic question.
Current molecular medicine 2008;8(2):78-91.
2008: Büttner Sabrina; Bitto Alessandro; Ring Julia; Augsten Manuela; Zabrocki Piotr; Eisenberg Tobias; Jungwirth Helmut; Hutter Sylvia; Carmona-Gutierrez Didac; Kroemer Guido; Winderickx Joris; Madeo Frank
Functional mitochondria are required for alpha-synuclein toxicity in aging yeast.
The Journal of biological chemistry 2008;283(12):7554-60.
2008: Tufi R; Panaretakis T; Bianchi K; Criollo A; Fazi B; Di Sano F; Tesniere A; Kepp O; Paterlini-Brechot P; Zitvogel L; Piacentini M; Szabadkai G; Kroemer G
Reduction of endoplasmic reticulum Ca2+ levels favors plasma membrane surface exposure of calreticulin.
Cell death and differentiation 2008;15(2):274-82.
2008: Boehrer Simone; Adès Lionel; Braun Thorsten; Galluzzi Lorenzo; Grosjean Jennifer; Fabre Claire; Le Roux Génèviève; Gardin Claude; Martin Antoine; de Botton Stéphane; Fenaux Pierre; Kroemer Guido
Erlotinib exhibits antineoplastic off-target effects in AML and MDS: a preclinical study.
Blood 2008;111(4):2170-80.
2008: Zitvogel Laurence; Apetoh Lionel; Ghiringhelli François; Kroemer Guido
Immunological aspects of cancer chemotherapy.
Nature reviews. Immunology 2008;8(1):59-73.
2008: Zitvogel L; Kroemer G
The immune response against dying tumor cells: avoid disaster, achieve cure.
Cell death and differentiation 2008;15(1):1-2.
2008: Tesniere A; Panaretakis T; Kepp O; Apetoh L; Ghiringhelli F; Zitvogel L; Kroemer G
Molecular characteristics of immunogenic cancer cell death.
Cell death and differentiation 2008;15(1):3-12.
2008: Ullrich E; Bonmort M; Mignot G; Kroemer G; Zitvogel L
Tumor stress, cell death and the ensuing immune response.
Cell death and differentiation 2008;15(1):21-8.
2008: Deniaud A; Sharaf el dein O; Maillier E; Poncet D; Kroemer G; Lemaire C; Brenner C
Endoplasmic reticulum stress induces calcium-dependent permeability transition, mitochondrial outer membrane permeabilization and apoptosis.
Oncogene 2008;27(3):285-99.
2008: Galluzzi Lorenzo; Vitale Ilio; Kepp Oliver; Séror Claire; Hangen Emilie; Perfettini Jean-Luc; Modjtahedi Nazanine; Kroemer Guido
Methods to dissect mitochondrial membrane permeabilization in the course of apoptosis.
Methods in enzymology 2008;442():355-74.
2008: Perfettini Jean-Luc; Nardacci Roberta; Bourouba Mehdi; Subra Frédéric; Gros Laurent; Séror Claire; Manic Gwenola; Rosselli Filippo; Amendola Alessandra; Masdehors Peggy; Chessa Luciana; Novelli Giuseppe; Ojcius David M; Siwicki Jan Konrad; Chechlinska Magdalena; Auclair Christian; Regueiro José R; de Thé Hugues; Gougeon Marie-Lise; Piacentini Mauro; Kroemer Guido
Critical involvement of the ATM-dependent DNA damage response in the apoptotic demise of HIV-1-elicited syncytia.
PloS one 2008;3(6):e2458.
2008: Vicencio José Miguel; Galluzzi Lorenzo; Tajeddine Nicolas; Ortiz Carla; Criollo Alfredo; Tasdemir Ezgi; Morselli Eugenia; Ben Younes Amena; Maiuri Maria Chiara; Lavandero Sergio; Kroemer Guido
Senescence, apoptosis or autophagy? When a damaged cell must decide its path--a mini-review.
Gerontology 2008;54(2):92-9.
2008: Tasdemir Ezgi; Galluzzi Lorenzo; Maiuri M Chiara; Criollo Alfredo; Vitale Ilio; Hangen Emilie; Modjtahedi Nazanine; Kroemer Guido
Methods for assessing autophagy and autophagic cell death.
Methods in molecular biology (Clifton, N.J.) 2008;445():29-76.
2007: Apetoh Lionel; Ghiringhelli François; Tesniere Antoine; Criollo Alfredo; Ortiz Carla; Lidereau Rosette; Mariette Christophe; Chaput Nathalie; Mira Jean-Paul; Delaloge Suzette; André Fabrice; Tursz Thomas; Kroemer Guido; Zitvogel Laurence
The interaction between HMGB1 and TLR4 dictates the outcome of anticancer chemotherapy and radiotherapy.
Immunological reviews 2007;220():47-59.
2007: Obeid Michel; Tesniere Antoine; Panaretakis Theocharis; Tufi Roberta; Joza Nick; van Endert Peter; Ghiringhelli François; Apetoh Lionel; Chaput Nathalie; Flament Caroline; Ullrich Evelyn; de Botton Stéphane; Zitvogel Laurence; Kroemer Guido
Ecto-calreticulin in immunogenic chemotherapy.
Immunological reviews 2007;220():22-34.
2007: Zermati Yael; Mouhamad Shahul; Stergiou Lilli; Besse Benjamin; Galluzzi Lorenzo; Boehrer Simone; Pauleau Anne-Laure; Rosselli Filippo; D'Amelio Marcello; Amendola Roberto; Castedo Maria; Hengartner Michael; Soria Jean-Charles; Cecconi Francesco; Kroemer Guido
Nonapoptotic role for Apaf-1 in the DNA damage checkpoint.
Molecular cell 2007;28(4):624-37.
2007: Pospisilik J Andrew; Knauf Claude; Joza Nicholas; Benit Paule; Orthofer Michael; Cani Patrice D; Ebersberger Ingo; Nakashima Tomoki; Sarao Renu; Neely Gregory; Esterbauer Harald; Kozlov Andrey; Kahn C Ronald; Kroemer Guido; Rustin Pierre; Burcelin Remy; Penninger Josef M
Targeted deletion of AIF decreases mitochondrial oxidative phosphorylation and protects from obesity and diabetes.
Cell 2007;131(3):476-91.
2007: Pauleau A-L; Larochette N; Giordanetto F; Scholz S R; Poncet D; Zamzami N; Goldmacher V S; Kroemer G
Structure-function analysis of the interaction between Bax and the cytomegalovirus-encoded protein vMIA.
Oncogene 2007;26(50):7067-80.
2007: Olaussen Ken A; Fouret Pierre; Kroemer Guido
ERCC1-specific immunostaining in non-small-cell lung cancer.
The New England journal of medicine 2007;357(15):1559-61.
2007: Chaput Nathalie; De Botton Stéphane; Obeid Michel; Apetoh Lionel; Ghiringhelli François; Panaretakis Theocharis; Flament Caroline; Zitvogel Laurence; Kroemer Guido
Molecular determinants of immunogenic cell death: surface exposure of calreticulin makes the difference.
Journal of molecular medicine (Berlin, Germany) 2007;85(10):1069-76.
2007: Obeid M; Panaretakis T; Joza N; Tufi R; Tesniere A; van Endert P; Zitvogel L; Kroemer G
Calreticulin exposure is required for the immunogenicity of gamma-irradiation and UVC light-induced apoptosis.
Cell death and differentiation 2007;14(10):1848-50.
2007: Tasdemir Ezgi; Maiuri M Chiara; Tajeddine Nicolas; Vitale Ilio; Criollo Alfredo; Vicencio José Miguel; Hickman John A; Geneste Olivier; Kroemer Guido
Cell cycle-dependent induction of autophagy, mitophagy and reticulophagy.
Cell cycle (Georgetown, Tex.) 2007;6(18):2263-7.
2007: Obeid Michel; Panaretakis Theocharis; Tesniere Antoine; Joza Nick; Tufi Roberta; Apetoh Lionel; Ghiringhelli François; Zitvogel Laurence; Kroemer Guido
Leveraging the immune system during chemotherapy: moving calreticulin to the cell surface converts apoptotic death from "silent" to immunogenic.
Cancer research 2007;67(17):7941-4.
2007: Apetoh Lionel; Ghiringhelli François; Tesniere Antoine; Obeid Michel; Ortiz Carla; Criollo Alfredo; Mignot Grégoire; Maiuri M Chiara; Ullrich Evelyn; Saulnier Patrick; Yang Huan; Amigorena Sebastian; Ryffel Bernard; Barrat Franck J; Saftig Paul; Levi Francis; Lidereau Rosette; Nogues Catherine; Mira Jean-Paul; Chompret Agnès; Joulin Virginie; Clavel-Chapelon Françoise; Bourhis Jean; André Fabrice; Delaloge Suzette; Tursz Thomas; Kroemer Guido; Zitvogel Laurence
Toll-like receptor 4-dependent contribution of the immune system to anticancer chemotherapy and radiotherapy.
Nature medicine 2007;13(9):1050-9.
2007: Kroemer Guido
Cancer: defeating the immortal.
Cancer biology & therapy 2007;6(8):1324-8.
2007: Zhu Changlian; Wang Xiaoyang; Deinum Johanna; Huang Zhiheng; Gao Jianfeng; Modjtahedi Nazanine; Neagu Martha R; Nilsson Michael; Eriksson Peter S; Hagberg Henrik; Luban Jeremy; Kroemer Guido; Blomgren Klas
Cyclophilin A participates in the nuclear translocation of apoptosis-inducing factor in neurons after cerebral hypoxia-ischemia.
The Journal of experimental medicine 2007;204(8):1741-8.
2007: de La Motte Rouge Thibault; Galluzzi Lorenzo; Olaussen Ken A; Zermati Yael; Tasdemir Ezgi; Robert Thomas; Ripoche Hugues; Lazar Vladimir; Dessen Philippe; Harper Francis; Pierron Gerard; Pinna Guillaume; Araujo Natalia; Harel-Belan Annick; Armand Jean-Pierre; Wong Tai Wai; Soria Jean Charles; Kroemer Guido
A novel epidermal growth factor receptor inhibitor promotes apoptosis in non-small cell lung cancer cells resistant to erlotinib.
Cancer research 2007;67(13):6253-62.
2007: Maiuri Maria Chiara; Criollo Alfredo; Tasdemir Ezgi; Vicencio José Miguel; Tajeddine Nicolas; Hickman John A; Geneste Olivier; Kroemer Guido
BH3-only proteins and BH3 mimetics induce autophagy by competitively disrupting the interaction between Beclin 1 and Bcl-2/Bcl-X(L).
Autophagy 2007;3(4):374-6.
2007: Galluzzi L; Maiuri M C; Vitale I; Zischka H; Castedo M; Zitvogel L; Kroemer G
Cell death modalities: classification and pathophysiological implications.
Cell death and differentiation 2007;14(7):1237-43.
2007: Criollo Alfredo; Vicencio José Miguel; Tasdemir Ezgi; Maiuri M Chiara; Lavandero Sergio; Kroemer Guido
The inositol trisphosphate receptor in the control of autophagy.
Autophagy 2007;3(4):350-3.
2007: Braun Thorsten; Carvalho Gabrielle; Grosjean Jennifer; Ades Lionel; Fabre Claire; Boehrer Simone; Debili Najet; Fenaux Pierre; Kroemer Guido
Differentiating megakaryocytes in myelodysplastic syndromes succumb to mitochondrial derangement without caspase activation.
Apoptosis : an international journal on programmed cell death 2007;12(6):1101-8.
2007: Fabre C; Carvalho G; Tasdemir E; Braun T; Adès L; Grosjean J; Boehrer S; Métivier D; Souquère S; Pierron G; Fenaux P; Kroemer G
NF-kappaB inhibition sensitizes to starvation-induced cell death in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Oncogene 2007;26(28):4071-83.
2007: Büttner Sabrina; Carmona-Gutierrez Didac; Vitale Ilio; Castedo Maria; Ruli Doris; Eisenberg Tobias; Kroemer Guido; Madeo Frank
Depletion of endonuclease G selectively kills polyploid cells.
Cell cycle (Georgetown, Tex.) 2007;6(9):1072-6.
2007: Eisenberg Tobias; Büttner Sabrina; Kroemer Guido; Madeo Frank
The mitochondrial pathway in yeast apoptosis.
Apoptosis : an international journal on programmed cell death 2007;12(5):1011-23.
2007: Maiuri M Chiara; Le Toumelin Gaëtane; Criollo Alfredo; Rain Jean-Christophe; Gautier Fabien; Juin Philippe; Tasdemir Ezgi; Pierron Gérard; Troulinaki Kostoula; Tavernarakis Nektarios; Hickman John A; Geneste Olivier; Kroemer Guido
Functional and physical interaction between Bcl-X(L) and a BH3-like domain in Beclin-1.
The EMBO journal 2007;26(10):2527-39.
2007: Galluzzi Lorenzo; Zamzami Naoufal; de La Motte Rouge Thibault; Lemaire Christophe; Brenner Catherine; Kroemer Guido
Methods for the assessment of mitochondrial membrane permeabilization in apoptosis.
Apoptosis : an international journal on programmed cell death 2007;12(5):803-13.
2007: Criollo A; Maiuri M C; Tasdemir E; Vitale I; Fiebig A A; Andrews D; Molgó J; Díaz J; Lavandero S; Harper F; Pierron G; di Stefano D; Rizzuto R; Szabadkai G; Kroemer G
Regulation of autophagy by the inositol trisphosphate receptor.
Cell death and differentiation 2007;14(5):1029-39.
2007: Ghiringhelli François; Apetoh Lionel; Housseau Frank; Kroemer Guido; Zitvogel Laurence
Links between innate and cognate tumor immunity.
Current opinion in immunology 2007;19(2):224-31.
2007: Raslova Hana; Kauffmann Audrey; Sekkaï Dalila; Ripoche Hugues; Larbret Fréderic; Robert Thomas; Le Roux Diana Tronik; Kroemer Guido; Debili Najet; Dessen Philippe; Lazar Vladimir; Vainchenker William
Interrelation between polyploidization and megakaryocyte differentiation: a gene profiling approach.
Blood 2007;109(8):3225-34.
2007: Tarze A; Deniaud A; Le Bras M; Maillier E; Molle D; Larochette N; Zamzami N; Jan G; Kroemer G; Brenner C
GAPDH, a novel regulator of the pro-apoptotic mitochondrial membrane permeabilization.
Oncogene 2007;26(18):2606-20.
2007: Carvalho G; Fabre C; Braun T; Grosjean J; Ades L; Agou F; Tasdemir E; Boehrer S; Israel A; Véron M; Fenaux P; Kroemer G
Inhibition of NEMO, the regulatory subunit of the IKK complex, induces apoptosis in high-risk myelodysplastic syndrome and acute myeloid leukemia.
Oncogene 2007;26(16):2299-307.
2007: Zhu C; Wang X; Huang Z; Qiu L; Xu F; Vahsen N; Nilsson M; Eriksson P S; Hagberg H; Culmsee C; Plesnila N; Kroemer G; Blomgren K
Apoptosis-inducing factor is a major contributor to neuronal loss induced by neonatal cerebral hypoxia-ischemia.
Cell death and differentiation 2007;14(4):775-84.
2007: Apetoh Lionel; Obeid Michel; Tesniere Antoine; Ghiringhelli François; Fimia Gian Maria; Piacentini Mauro; Kroemer Guido; Zitvogel Laurence
Immunogenic chemotherapy: discovery of a critical protein through proteomic analyses of tumor cells.
Cancer genomics & proteomics 2007;4(2):65-70.
2007: Ullrich Evelyn; Bonmort Mathieu; Mignot Grégoire; Chaput Nathalie; Taieb Julien; Ménard Cédric; Viaud Sophie; Tursz Thomas; Kroemer Guido; Zitvogel Laurence
Therapy-induced tumor immunosurveillance involves IFN-producing killer dendritic cells.
Cancer research 2007;67(3):851-3.
2007: Feraud O; Debili N; Penninger J M; Kroemer G
Cavitation of embryoid bodies requires optimal oxidative phosphorylation and AIF.
Cell death and differentiation 2007;14(2):385-7.
2007: Kroemer Guido; Galluzzi Lorenzo; Brenner Catherine
Mitochondrial membrane permeabilization in cell death.
Physiological reviews 2007;87(1):99-163.
2007: Obeid Michel; Tesniere Antoine; Ghiringhelli François; Fimia Gian Maria; Apetoh Lionel; Perfettini Jean-Luc; Castedo Maria; Mignot Grégoire; Panaretakis Theoharis; Casares Noelia; Métivier Didier; Larochette Nathanael; van Endert Peter; Ciccosanti Fabiola; Piacentini Mauro; Zitvogel Laurence; Kroemer Guido
Calreticulin exposure dictates the immunogenicity of cancer cell death.
Nature medicine 2007;13(1):54-61.
2007: Criollo Alfredo; Galluzzi Lorenzo; Maiuri M Chiara; Tasdemir Ezgi; Lavandero Sergio; Kroemer Guido
Mitochondrial control of cell death induced by hyperosmotic stress.
Apoptosis : an international journal on programmed cell death 2007;12(1):3-18.
2007: Riefke Björn; Mumberg Dominik; Kroemer Guido; Keun Hector; Petersen Kirstin; Steger-Hartmann Thomas
Oncogenes meet metabolism. From deregulated genes to a broader understanding of tumour physiology. Preface.
Ernst Schering Foundation symposium proceedings 2007;(4):V-VII.
2007: Vitale Ilio; Galluzzi Lorenzo; Vivet Sonia; Nanty Lisa; Dessen Philippe; Senovilla Laura; Olaussen Ken A; Lazar Vladimir; Prudhomme Michelle; Golsteyn Roy M; Castedo Maria; Kroemer Guido
Inhibition of Chk1 kills tetraploid tumor cells through a p53-dependent pathway.
PloS one 2007;2(12):e1337.
2007: Zamzami Naoufal; Maisse Carine; Métivier Didier; Kroemer Guido
Measurement of membrane permeability and the permeability transition of mitochondria.
Methods in cell biology 2007;80():327-40.
2006: Castedo Maria; Coquelle Arnaud; Vitale Ilio; Vivet Sonia; Mouhamad Shahul; Viaud Sophie; Zitvogel Laurence; Kroemer Guido
Selective resistance of tetraploid cancer cells against DNA damage-induced apoptosis.
Annals of the New York Academy of Sciences 2006;1090():35-49.
2006: Tesniere Antoine; Zitvogel Laurence; Kroemer Guido
The immune system: taming and unleashing cancer.
Discovery medicine 2006;6(36):211-6.
2006: Zhang P; Castedo M; Tao Y; Violot D; Métivier D; Deutsch E; Kroemer G; Bourhis Jean
Caspase independence of radio-induced cell death.
Oncogene 2006;25(59):7758-70.
2006: Garrido Carmen; Brunet Mathilde; Didelot Celine; Zermati Yael; Schmitt Elise; Kroemer Guido
Heat shock proteins 27 and 70: anti-apoptotic proteins with tumorigenic properties.
Cell cycle (Georgetown, Tex.) 2006;5(22):2592-601.
2006: Büttner Sabrina; Eisenberg Tobias; Herker Eva; Carmona-Gutierrez Didac; Kroemer Guido; Madeo Frank
Why yeast cells can undergo apoptosis: death in times of peace, love, and war.
The Journal of cell biology 2006;175(4):521-5.
2006: Coquelle Arnaud; Mouhamad Shahul; Pequignot Marie O; Braun Thorsten; Carvalho Gabrielle; Vivet Sonia; Métivier Didier; Castedo Maria; Kroemer Guido
Enrichment of non-synchronized cells in the G1, S and G2 phases of the cell cycle for the study of apoptosis.
Biochemical pharmacology 2006;72(11):1396-404.
2006: Zitvogel Laurence; Tesniere Antoine; Kroemer Guido
Cancer despite immunosurveillance: immunoselection and immunosubversion.
Nature reviews. Immunology 2006;6(10):715-27.
2006: Poncet Delphine; Pauleau Anne-Laure; Szabadkai Gyorgy; Vozza Angelo; Scholz Sebastian R; Le Bras Morgane; Brière Jean-Jacques; Jalil Abdelali; Le Moigne Ronan; Brenner Catherine; Hahn Gabriele; Wittig Ilka; Schägger Hermann; Lemaire Christophe; Bianchi Katiuscia; Souquère Sylvie; Pierron Gerard; Rustin Pierre; Goldmacher Victor S; Rizzuto Rosario; Palmieri Ferdinando; Kroemer Guido
Cytopathic effects of the cytomegalovirus-encoded apoptosis inhibitory protein vMIA.
The Journal of cell biology 2006;174(7):985-96.
2006: Le Bras Morgane; Borgne-Sanchez Annie; Touat Zahia; El Dein Ossama Sharaf; Deniaud Aurélien; Maillier Evelyne; Lecellier Gael; Rebouillat Dominique; Lemaire Christophe; Kroemer Guido; Jacotot Etienne; Brenner Catherine
Chemosensitization by knockdown of adenine nucleotide translocase-2.
Cancer research 2006;66(18):9143-52.
2006: Garrido C; Galluzzi L; Brunet M; Puig P E; Didelot C; Kroemer G
Mechanisms of cytochrome c release from mitochondria.
Cell death and differentiation 2006;13(9):1423-33.
2006: Galluzzi L; Larochette N; Zamzami N; Kroemer G
Mitochondria as therapeutic targets for cancer chemotherapy.
Oncogene 2006;25(34):4812-30.
2006: Kroemer G
Mitochondria in cancer.
Oncogene 2006;25(34):4630-2.
2006: Massard C; Zermati Y; Pauleau A-L; Larochette N; Métivier D; Sabatier L; Kroemer G; Soria J-C
hTERT: a novel endogenous inhibitor of the mitochondrial cell death pathway.
Oncogene 2006;25(33):4505-14.
2006: Castedo Maria; Coquelle Arnaud; Vivet Sonia; Vitale Ilio; Kauffmann Audrey; Dessen Philippe; Pequignot Marie O; Casares Noelia; Valent Alexandre; Mouhamad Shahul; Schmitt Elise; Modjtahedi Nazanine; Vainchenker William; Zitvogel Laurence; Lazar Vladimir; Garrido Carmen; Kroemer Guido
Apoptosis regulation in tetraploid cancer cells.
The EMBO journal 2006;25(11):2584-95.
2006: Modjtahedi Nazanine; Giordanetto Fabrizio; Madeo Frank; Kroemer Guido
Apoptosis-inducing factor: vital and lethal.
Trends in cell biology 2006;16(5):264-72.
2006: Braun T; Carvalho G; Fabre C; Grosjean J; Fenaux P; Kroemer G
Targeting NF-kappaB in hematologic malignancies.
Cell death and differentiation 2006;13(5):748-58.
2006: Coquelle A; Mouhamad S; Pequignot M O; Braun T; Carvalho G; Vivet S; Métivier D; Castedo M; Kroemer G
Cell cycle-dependent cytotoxic and cytostatic effects of bortezomib on colon carcinoma cells.
Cell death and differentiation 2006;13(5):873-5.
2006: Schmitt Elise; Maingret Loic; Puig Pierre-Emmanuel; Rerole Anne-Laure; Ghiringhelli François; Hammann Arlette; Solary Eric; Kroemer Guido; Garrido Carmen
Heat shock protein 70 neutralization exerts potent antitumor effects in animal models of colon cancer and melanoma.
Cancer research 2006;66(8):4191-7.
2006: Vahsen N; Candé C; Dupaigne P; Giordanetto F; Kroemer R T; Herker E; Scholz S; Modjtahedi N; Madeo F; Le Cam E; Kroemer G
Physical interaction of apoptosis-inducing factor with DNA and RNA.
Oncogene 2006;25(12):1763-74.
2006: Sabbah Emmanuelle N; Druillennec S; Morellet N; Bouaziz S; Kroemer G; Roques B P
Interaction between the HIV-1 protein Vpr and the adenine nucleotide translocator.
Chemical biology & drug design 2006;67(2):145-54.
2006: Taieb Julien; Chaput Nathalie; Ménard Cédric; Apetoh Lionel; Ullrich Evelyn; Bonmort Mathieu; Péquignot Marie; Casares Noelia; Terme Magali; Flament Caroline; Opolon Paule; Lecluse Yann; Métivier Didier; Tomasello Elena; Vivier Eric; Ghiringhelli François; Martin François; Klatzmann David; Poynard Thierry; Tursz Thomas; Raposo Graça; Yagita Hideo; Ryffel Bernard; Kroemer Guido; Zitvogel Laurence
A novel dendritic cell subset involved in tumor immunosurveillance.
Nature medicine 2006;12(2):214-9.
2006: Braun Thorsten; Carvalho Gabrielle; Coquelle Arnaud; Vozenin Marie-Catherine; Lepelley Pascale; Hirsch François; Kiladjian Jean-Jacques; Ribrag Vincent; Fenaux Pierre; Kroemer Guido
NF-kappaB constitutes a potential therapeutic target in high-risk myelodysplastic syndrome.
Blood 2006;107(3):1156-65.
2005: Casares Noelia; Pequignot Marie O; Tesniere Antoine; Ghiringhelli François; Roux Stéphan; Chaput Nathalie; Schmitt Elise; Hamai Ahmed; Hervas-Stubbs Sandra; Obeid Michel; Coutant Frédéric; Métivier Didier; Pichard Evelyne; Aucouturier Pierre; Pierron Gérard; Garrido Carmen; Zitvogel Laurence; Kroemer Guido
Caspase-dependent immunogenicity of doxorubicin-induced tumor cell death.
The Journal of experimental medicine 2005;202(12):1691-701.
2005: Joza Nicholas; Oudit Gavin Y; Brown Doris; Bénit Paule; Kassiri Zamaneh; Vahsen Nicola; Benoit Loralyn; Patel Mikin M; Nowikovsky Karin; Vassault Anne; Backx Peter H; Wada Teiji; Kroemer Guido; Rustin Pierre; Penninger Josef M
Muscle-specific loss of apoptosis-inducing factor leads to mitochondrial dysfunction, skeletal muscle atrophy, and dilated cardiomyopathy.
Molecular and cellular biology 2005;25(23):10261-72.
2005: Zamzami N; Larochette N; Kroemer G
Mitochondrial permeability transition in apoptosis and necrosis.
Cell death and differentiation 2005;12 Suppl 2():1478-80.
2005: Kroemer G; El-Deiry W S; Golstein P; Peter M E; Vaux D; Vandenabeele P; Zhivotovsky B; Blagosklonny M V; Malorni W; Knight R A; Piacentini M; Nagata S; Melino G;
Classification of cell death: recommendations of the Nomenclature Committee on Cell Death.
Cell death and differentiation 2005;12 Suppl 2():1463-7.
2005: Kroemer Guido; Jäättelä Marja
Lysosomes and autophagy in cell death control.
Nature reviews. Cancer 2005;5(11):886-97.
2005: Gonzalez-Polo Rosa-Ana; Carvalho Gabrielle; Braun Thorsten; Decaudin Didier; Fabre Claire; Larochette Nathanael; Perfettini Jean-Luc; Djavaheri-Mergny Mojgan; Youlyouz-Marfak Ibtissam; Codogno Patrice; Raphael Martine; Feuillard Jean; Kroemer Guido
PK11195 potently sensitizes to apoptosis induction independently from the peripheral benzodiazepin receptor.
Oncogene 2005;24(51):7503-13.
2005: Ghiringhelli François; Puig Pierre E; Roux Stephan; Parcellier Arnaud; Schmitt Elise; Solary Eric; Kroemer Guido; Martin François; Chauffert Bruno; Zitvogel Laurence
Tumor cells convert immature myeloid dendritic cells into TGF-beta-secreting cells inducing CD4+CD25+ regulatory T cell proliferation.
The Journal of experimental medicine 2005;202(7):919-29.
2005: Perfettini J-L; Castedo M; Roumier T; Andreau K; Nardacci R; Piacentini M; Kroemer G
Mechanisms of apoptosis induction by the HIV-1 envelope.
Cell death and differentiation 2005;12 Suppl 1():916-23.
2005: Kroemer Guido; Martin Seamus J
Caspase-independent cell death.
Nature medicine 2005;11(7):725-30.
2005: González-Polo Rosa-Ana; Boya Patricia; Pauleau Anne-Laure; Jalil Abdelali; Larochette Nathanael; Souquère Sylvie; Eskelinen Eeva-Liisa; Pierron Gérard; Saftig Paul; Kroemer Guido
The apoptosis/autophagy paradox: autophagic vacuolization before apoptotic death.
Journal of cell science 2005;118(Pt 14):3091-102.
2005: Weaver Joel G R; Tarze Agathe; Moffat Tia C; Lebras Morgane; Deniaud Aurelien; Brenner Catherine; Bren Gary D; Morin Mario Y; Phenix Barbara N; Dong Li; Jiang Susan X; Sim Valerie L; Zurakowski Bogdan; Lallier Jessica; Hardin Heather; Wettstein Peter; van Heeswijk Rolf P G; Douen Andre; Kroemer Romano T; Hou Sheng T; Bennett Steffany A L; Lynch David H; Kroemer Guido; Badley Andrew D
Inhibition of adenine nucleotide translocator pore function and protection against apoptosis in vivo by an HIV protease inhibitor.
The Journal of clinical investigation 2005;115(7):1828-38.
2005: Castedo Maria; Perfettini Jean-Luc; Piacentini Mauro; Kroemer Guido
p53-A pro-apoptotic signal transducer involved in AIDS.
Biochemical and biophysical research communications 2005;331(3):701-6.
2005: Zamzami Naoufal; Kroemer Guido
p53 in apoptosis control: an introduction.
Biochemical and biophysical research communications 2005;331(3):685-7.
2005: Perfettini Jean-Luc; Roumier Thomas; Kroemer Guido
Mitochondrial fusion and fission in the control of apoptosis.
Trends in cell biology 2005;15(4):179-83.
2005: Boya Patricia; González-Polo Rosa-Ana; Casares Noelia; Perfettini Jean-Luc; Dessen Philippe; Larochette Nathanael; Métivier Didier; Meley Daniel; Souquere Sylvie; Yoshimori Tamotsu; Pierron Gérard; Codogno Patrice; Kroemer Guido
Inhibition of macroautophagy triggers apoptosis.
Molecular and cellular biology 2005;25(3):1025-40.
2005: Perfettini Jean-Luc; Castedo Maria; Nardacci Roberta; Ciccosanti Fabiola; Boya Patricia; Roumier Thomas; Larochette Nathanael; Piacentini Mauro; Kroemer Guido
Essential role of p53 phosphorylation by p38 MAPK in apoptosis induction by the HIV-1 envelope.
The Journal of experimental medicine 2005;201(2):279-89.
2005: Carvalho Gabrielle; Lefaucheur Carmen; Cherbonnier Claire; Métivier Didier; Chapel Alain; Pallardy Marc; Bourgeade Marie-Françoise; Charpentier Bernard; Hirsch François; Kroemer Guido
Chemosensitization by erythropoietin through inhibition of the NF-kappaB rescue pathway.
Oncogene 2005;24(5):737-45.
2004: Boya Patricia; Pauleau Anne-Laure; Poncet Delphine; Gonzalez-Polo Rosa-Ana; Zamzami Naoufal; Kroemer Guido
Viral proteins targeting mitochondria: controlling cell death.
Biochimica et biophysica acta 2004;1659(2-3):178-89.
2004: Garrido Carmen; Kroemer Guido
Life's smile, death's grin: vital functions of apoptosis-executing proteins.
Current opinion in cell biology 2004;16(6):639-46.
2004: Andreau Karine; Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Pichart Evelyne; Souquere Sylvie; Vivet Sonia; Larochette Nathanael; Kroemer Guido
Preapoptotic chromatin condensation upstream of the mitochondrial checkpoint.
The Journal of biological chemistry 2004;279(53):55937-45.
2004: Vahsen Nicola; Candé Céline; Brière Jean-Jacques; Bénit Paule; Joza Nicholas; Larochette Nathanael; Mastroberardino Pier Giorgio; Pequignot Marie O; Casares Noelia; Lazar Vladimir; Feraud Olivier; Debili Najet; Wissing Silke; Engelhardt Silvia; Madeo Frank; Piacentini Mauro; Penninger Josef M; Schägger Hermann; Rustin Pierre; Kroemer Guido
AIF deficiency compromises oxidative phosphorylation.
The EMBO journal 2004;23(23):4679-89.
2004: Aguirre D; Boya P; Bellet D; Faivre S; Troalen F; Benard J; Saulnier P; Hopkins-Donaldson S; Zangemeister-Wittke U; Kroemer G; Raymond E
Bcl-2 and CCND1/CDK4 expression levels predict the cellular effects of mTOR inhibitors in human ovarian carcinoma.
Apoptosis : an international journal on programmed cell death 2004;9(6):797-805.
2004: Andreau Karine; Perfettini Jean-Luc; Castedo Maria; Métivier Didier; Scott Véronique; Pierron Gérard; Kroemer Guido
Contagious apoptosis facilitated by the HIV-1 envelope: fusion-induced cell-to-cell transmission of a lethal signal.
Journal of cell science 2004;117(Pt 23):5643-53.
2004: Verrier Florence; Deniaud Aurélien; Lebras Morgane; Métivier Didier; Kroemer Guido; Mignotte Bernard; Jan Gwenaël; Brenner Catherine
Dynamic evolution of the adenine nucleotide translocase interactome during chemotherapy-induced apoptosis.
Oncogene 2004;23(49):8049-64.
2004: Wissing Silke; Ludovico Paula; Herker Eva; Büttner Sabrina; Engelhardt Silvia M; Decker Thorsten; Link Alexander; Proksch Astrid; Rodrigues Fernando; Corte-Real Manuela; Fröhlich Kai-Uwe; Manns Joachim; Candé Céline; Sigrist Stephan J; Kroemer Guido; Madeo Frank
An AIF orthologue regulates apoptosis in yeast.
The Journal of cell biology 2004;166(7):969-74.
2004: Besse Benjamin; Candé Céline; Spano Jean-Philippe; Martin Antoine; Khayat David; Le Chevalier Thierry; Tursz Thomas; Sabatier Laure; Soria Jean-Charles; Kroemer Guido
Nuclear localization of apoptosis protease activating factor-1 predicts survival after tumor resection in early-stage non-small cell lung cancer.
Clinical cancer research : an official journal of the American Association for Cancer Research 2004;10(17):5665-9.
2004: Gourdier Isabelle; Crabbe Laure; Andreau Karine; Pau Bernard; Kroemer Guido
Oxaliplatin-induced mitochondrial apoptotic response of colon carcinoma cells does not require nuclear DNA.
Oncogene 2004;23(45):7449-57.
2004: Candé Céline; Vahsen Nicola; Métivier Didier; Tourrière Hélène; Chebli Karim; Garrido Carmen; Tazi Jamal; Kroemer Guido
Regulation of cytoplasmic stress granules by apoptosis-inducing factor.
Journal of cell science 2004;117(Pt 19):4461-8.
2004: Deniaud Aurélien; Brenner Catherine; Kroemer Guido
Mitochondrial membrane permeabilization by HIV-1 Vpr.
Mitochondrion 2004;4(2-3):223-33.
2004: Candé C; Vahsen N; Garrido C; Kroemer G
Apoptosis-inducing factor (AIF): caspase-independent after all.
Cell death and differentiation 2004;11(6):591-5.
2004: Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Valent Alexander; Raslova Hana; Yakushijin Kenichi; Horne David; Feunteun Jean; Lenoir Gilbert; Medema René; Vainchenker William; Kroemer Guido
Mitotic catastrophe constitutes a special case of apoptosis whose suppression entails aneuploidy.
Oncogene 2004;23(25):4362-70.
2004: Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Yakushijin Kenichi; Horne David; Medema René; Kroemer Guido
The cell cycle checkpoint kinase Chk2 is a negative regulator of mitotic catastrophe.
Oncogene 2004;23(25):4353-61.
2004: Poncet Delphine; Larochette Nathanael; Pauleau Anne-Laure; Boya Patricia; Jalil Abdel-Ali; Cartron Pierre-Francois; Vallette Francois; Schnebelen Céline; Bartle Laura M; Skaletskaya Anna; Boutolleau David; Martinou Jean-Claude; Goldmacher Victor S; Kroemer Guido; Zamzami Naoufal
An anti-apoptotic viral protein that recruits Bax to mitochondria.
The Journal of biological chemistry 2004;279(21):22605-14.
2004: Schmitt Elise; Parcellier Arnaud; Ghiringhelli François; Casares Noelia; Gurbuxani Sandeep; Droin Nathalie; Hamai Ahmed; Pequignot Marie; Hammann Arlette; Moutet Monique; Fromentin Annie; Kroemer Guido; Solary Eric; Garrido Carmen
Increased immunogenicity of colon cancer cells by selective depletion of cytochrome C.
Cancer research 2004;64(8):2705-11.
2004: Castedo Maria; Perfettini Jean-Luc; Roumier Thomas; Andreau Karine; Medema Rene; Kroemer Guido
Cell death by mitotic catastrophe: a molecular definition.
Oncogene 2004;23(16):2825-37.
2004: Cohen I; Boya P; Zhao L; Métivier D; Andreau K; Perfettini J-L; Weaver J G; Badley A; Taylor E W; Kroemer G
Anti-apoptotic activity of the glutathione peroxidase homologue encoded by HIV-1.
Apoptosis : an international journal on programmed cell death 2004;9(2):181-92.
2004: Perfettini Jean-Luc; Roumier Thomas; Castedo Maria; Larochette Nathanael; Boya Patricia; Raynal Brigitte; Lazar Vladimir; Ciccosanti Fabiola; Nardacci Roberta; Penninger Josef; Piacentini Mauro; Kroemer Guido
NF-kappaB and p53 are the dominant apoptosis-inducing transcription factors elicited by the HIV-1 envelope.
The Journal of experimental medicine 2004;199(5):629-40.
2004: Tintignac Lionel A J; Sirri Valentina; Leibovitch Marie Pierre; Lécluse Yann; Castedo Maria; Metivier Didier; Kroemer Guido; Leibovitch Serge A
Mutant MyoD lacking Cdc2 phosphorylation sites delays M-phase entry.
Molecular and cellular biology 2004;24(4):1809-21.
2004: Candé Céline; Vahsen Nicola; Kouranti Ilektra; Schmitt Elise; Daugas Eric; Spahr Chris; Luban Jeremy; Kroemer Romano T; Giordanetto Fabrizio; Garrido Carmen; Penninger Josef M; Kroemer Guido
AIF and cyclophilin A cooperate in apoptosis-associated chromatinolysis.
Oncogene 2004;23(8):1514-21.
2004: Castedo Maria; Kroemer Guido
[Mitotic catastrophe: a special case of apoptosis]
Journal de la Société de biologie 2004;198(2):97-103.
2004: Zitvogel Laurence; Casares Noelia; Péquignot Marie O; Chaput Nathalie; Albert Matthew L; Kroemer Guido
Immune response against dying tumor cells.
Advances in immunology 2004;84():131-79.
2004: Zamzami Naoufal; Kroemer Guido
Methods to measure membrane potential and permeability transition in the mitochondria during apoptosis.
Methods in molecular biology (Clifton, N.J.) 2004;282():103-15.
2003: Thoulouze Maria-Isabel; Lafage Mireille; Yuste Victor J; Kroemer Guido; Susin Santos A; Israel Nicole; Lafon Monique
Apoptosis inversely correlates with rabies virus neurotropism.
Annals of the New York Academy of Sciences 2003;1010():598-603.
2003: Castedo Maria; Perfettini Jean-Luc; Andreau Karine; Roumier Thomas; Piacentini Mauro; Kroemer Guido
Mitochondrial apoptosis induced by the HIV-1 envelope.
Annals of the New York Academy of Sciences 2003;1010():19-28.
2003: Schmitt Elise; Parcellier Arnaud; Gurbuxani Sandeep; Cande Celine; Hammann Arlette; Morales Maria Celia; Hunt Clayton R; Dix David J; Kroemer Romano T; Giordanetto Fabrizio; Jäättelä Marja; Penninger Josef M; Pance Alena; Kroemer Guido; Garrido Carmen
Chemosensitization by a non-apoptogenic heat shock protein 70-binding apoptosis-inducing factor mutant.
Cancer research 2003;63(23):8233-40.
2003: Garrido Carmen; Schmitt Elise; Candé Céline; Vahsen Nicola; Parcellier Arnaud; Kroemer Guido
HSP27 and HSP70: potentially oncogenic apoptosis inhibitors.
Cell cycle (Georgetown, Tex.) 2003;2(6):579-84.
2003: Vieira Helena; Kroemer Guido
Mitochondria as targets of apoptosis regulation by nitric oxide.
IUBMB life 2003;55(10-11):613-6.
2003: Poncet D; Boya P; Métivier D; Zamzami N; Kroemer G
Cytofluorometric quantitation of apoptosis-driven inner mitochondrial membrane permeabilization.
Apoptosis : an international journal on programmed cell death 2003;8(5):521-30.
2003: Gurbuxani Sandeep; Schmitt Elise; Cande Celine; Parcellier Arnaud; Hammann Arlette; Daugas Eric; Kouranti Ilektra; Spahr Chris; Pance Alena; Kroemer Guido; Garrido Carmen
Heat shock protein 70 binding inhibits the nuclear import of apoptosis-inducing factor.
Oncogene 2003;22(43):6669-78.
2003: Roumier Thomas; Castedo Maria; Perfettini Jean-Luc; Andreau Karine; Métivier Didier; Zamzami Naoufal; Kroemer Guido
Mitochondrion-dependent caspase activation by the HIV-1 envelope.
Biochemical pharmacology 2003;66(8):1321-9.
2003: Thoulouze Maria-Isabel; Lafage Mireille; Yuste Victor J; Baloul Leïla; Edelman Léna; Kroemer Guido; Israel Nicole; Susin Santos A; Lafon Monique
High level of Bcl-2 counteracts apoptosis mediated by a live rabies virus vaccine strain and induces long-term infection.
Virology 2003;314(2):549-61.
2003: Boya Patricia; Morales Maria Celia; Gonzalez-Polo Rosa-Ana; Andreau Karine; Gourdier Isabelle; Perfettini Jean-Luc; Larochette Nathanael; Deniaud Aurélien; Baran-Marszak Fanny; Fagard Remy; Feuillard Jean; Asumendi Aintzane; Raphael Martine; Pau Bernard; Brenner Catherine; Kroemer Guido
The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family.
Oncogene 2003;22(40):6220-30.
2003: Piacentini M; Evangelisti C; Mastroberardino P G; Nardacci R; Kroemer G
Does prothymosin-alpha act as molecular switch between apoptosis and autophagy?
Cell death and differentiation 2003;10(9):937-9.
2003: Kroemer Guido
The mitochondrial permeability transition pore complex as a pharmacological target. An introduction.
Current medicinal chemistry 2003;10(16):1469-72.
2003: Zhu Changlian; Qiu Lin; Wang Xiaoyang; Hallin Ulrika; Candé Céline; Kroemer Guido; Hagberg Henrik; Blomgren Klas
Involvement of apoptosis-inducing factor in neuronal death after hypoxia-ischemia in the neonatal rat brain.
Journal of neurochemistry 2003;86(2):306-17.
2003: Boya Patricia; Gonzalez-Polo Rosa-Ana; Poncet Delphine; Andreau Karine; Vieira Helena L A; Roumier Thomas; Perfettini Jean-Luc; Kroemer Guido
Mitochondrial membrane permeabilization is a critical step of lysosome-initiated apoptosis induced by hydroxychloroquine.
Oncogene 2003;22(25):3927-36.
2003: Boya Patricia; Andreau Karine; Poncet Delphine; Zamzami Naoufal; Perfettini Jean-Luc; Metivier Didier; Ojcius David M; Jäättelä Marja; Kroemer Guido
Lysosomal membrane permeabilization induces cell death in a mitochondrion-dependent fashion.
The Journal of experimental medicine 2003;197(10):1323-34.
2003: Brenner Catherine; Kroemer Guido
The mitochondriotoxic domain of Vpr determines HIV-1 virulence.
The Journal of clinical investigation 2003;111(10):1455-7.
2003: Boya Patricia; Roumier Thomas; Andreau Karine; Gonzalez-Polo Rosa Ana; Zamzami Naoufal; Castedo Maria; Kroemer Guido
Mitochondrion-targeted apoptosis regulators of viral origin.
Biochemical and biophysical research communications 2003;304(3):575-81.
2003: Kroemer Guido
Mitochondrial control of apoptosis: an introduction.
Biochemical and biophysical research communications 2003;304(3):433-5.
2003: Gougeon M-L; Kroemer G
Charming to death: caspase-dependent or -independent?
Cell death and differentiation 2003;10(3):390-2.
2003: Zamzami Naoufal; Kroemer Guido
Apoptosis: mitochondrial membrane permeabilization--the (w)hole story?
Current biology : CB 2003;13(2):R71-3.
2003: Belzacq Anne-Sophie; Vieira Helena L A; Verrier Florence; Vandecasteele Grégoire; Cohen Isabelle; Prévost Marie-Christine; Larquet Eric; Pariselli Fabrizio; Petit Patrice X; Kahn Axel; Rizzuto Rosario; Brenner Catherine; Kroemer Guido
Bcl-2 and Bax modulate adenine nucleotide translocase activity.
Cancer research 2003;63(2):541-6.
2003: Raslova Hana; Roy Lydia; Vourc'h Claire; Le Couedic Jean Pierre; Brison Olivier; Metivier Didier; Feunteun Jean; Kroemer Guido; Debili Najet; Vainchenker William
Megakaryocyte polyploidization is associated with a functional gene amplification.
Blood 2003;101(2):541-4.
2002: Castedo M; Perfettini J-L; Roumier T; Kroemer G
Cyclin-dependent kinase-1: linking apoptosis to cell cycle and mitotic catastrophe.
Cell death and differentiation 2002;9(12):1287-93.
2002: Candé Céline; Cecconi Francesco; Dessen Philippe; Kroemer Guido
Apoptosis-inducing factor (AIF): key to the conserved caspase-independent pathways of cell death?
Journal of cell science 2002;115(Pt 24):4727-34.
2002: Castedo Maria; Perfettini Jean-Luc; Kroemer Guido
Mitochondrial apoptosis and the peripheral benzodiazepine receptor: a novel target for viral and pharmacological manipulation.
The Journal of experimental medicine 2002;196(9):1121-5.
2002: Roumier T; Vieira H L A; Castedo M; Ferri K F; Boya P; Andreau K; Druillennec S; Joza N; Penninger J M; Roques B; Kroemer G
The C-terminal moiety of HIV-1 Vpr induces cell death via a caspase-independent mitochondrial pathway.
Cell death and differentiation 2002;9(11):1212-9.
2002: Haouzi D; Cohen I; Vieira H L A; Poncet D; Boya P; Castedo M; Vadrot N; Belzacq A-S; Fau D; Brenner C; Feldmann G; Kroemer G
Mitochondrial permeability transition as a novel principle of hepatorenal toxicity in vivo.
Apoptosis : an international journal on programmed cell death 2002;7(5):395-405.
2002: Castedo Maria; Kroemer Guido
The beauty of death.
Trends in cell biology 2002;12(9):446.
2002: Larmonier Nicolas; Billerey Claire; Rébé Cédric; Parcellier Arnaud; Moutet Monique; Fromentin Annie; Kroemer Guido; Garrido Carmen; Solary Eric; Martin François; Bonnotte Bernard
An atypical caspase-independent death pathway for an immunogenic cancer cell line.
Oncogene 2002;21(39):6091-100.
2002: Ye Hong; Cande Celine; Stephanou Nicolas C; Jiang Sulin; Gurbuxani Sundeep; Larochette Nathanael; Daugas Eric; Garrido Carmen; Kroemer Guido; Wu Hao
DNA binding is required for the apoptogenic action of apoptosis inducing factor.
Nature structural biology 2002;9(9):680-4.
2002: De Botton Stephane; Sabri Siham; Daugas Eric; Zermati Yael; Guidotti Jacques Emmanuel; Hermine Olivier; Kroemer Guido; Vainchenker William; Debili Najet
Platelet formation is the consequence of caspase activation within megakaryocytes.
Blood 2002;100(4):1310-7.
2002: Cregan Sean P; Fortin Andre; MacLaurin Jason G; Callaghan Steven M; Cecconi Francesco; Yu Seong-Woon; Dawson Ted M; Dawson Valina L; Park David S; Kroemer Guido; Slack Ruth S
Apoptosis-inducing factor is involved in the regulation of caspase-independent neuronal cell death.
The Journal of cell biology 2002;158(3):507-17.
2002: Castedo Maria; Roumier Thomas; Blanco Julià; Ferri Karine F; Barretina Jordi; Tintignac Lionel A; Andreau Karine; Perfettini Jean-Luc; Amendola Alessandra; Nardacci Roberta; Leduc Philip; Ingber Donald E; Druillennec Sabine; Roques Bernard; Leibovitch Serge A; Vilella-Bach Montserrat; Chen Jie; Este José A; Modjtahedi Nazanine; Piacentini Mauro; Kroemer Guido
Sequential involvement of Cdk1, mTOR and p53 in apoptosis induced by the HIV-1 envelope.
The EMBO journal 2002;21(15):4070-80.
2002: Ravagnan Luigi; Roumier Thomas; Kroemer Guido
Mitochondria, the killer organelles and their weapons.
Journal of cellular physiology 2002;192(2):131-7.
2002: Cohen Isabelle; Castedo Maria; Kroemer Guido
Tantalizing Thanatos: unexpected links in death pathways.
Trends in cell biology 2002;12(7):293-5.
2002: Castedo Maria; Ferri Karine; Roumier Thomas; Métivier Didier; Zamzami Naoufal; Kroemer Guido
Quantitation of mitochondrial alterations associated with apoptosis.
Journal of immunological methods 2002;265(1-2):39-47.
2002: Maté María J; Ortiz-Lombardía Miguel; Boitel Brigitte; Haouz Ahmed; Tello Diana; Susin Santos A; Penninger Josef; Kroemer Guido; Alzari Pedro M
The crystal structure of the mouse apoptosis-inducing factor AIF.
Nature structural biology 2002;9(6):442-6.
2002: Vieira Helena L A; Boya Patricia; Cohen Isabelle; El Hamel Chahrazed; Haouzi Delphine; Druillenec Sabine; Belzacq Anne-Sophie; Brenner Catherine; Roques Bernard; Kroemer Guido
Cell permeable BH3-peptides overcome the cytoprotective effect of Bcl-2 and Bcl-X(L).
Oncogene 2002;21(13):1963-77.
2002: Ameyar-Zazoua Maya; Larochette Nathanaël; Dorothée Guillaume; Daugas Eric; Haddada Hedi; Gouloumet Vanessa; Métivier Didier; Stancou Rodica; Mami-Chouaib Fathia; Kroemer Guido; Chouaib Salem
Wild-type p53 induced sensitization of mutant p53 TNF-resistant cells: role of caspase-8 and mitochondria.
Cancer gene therapy 2002;9(3):219-27.
2002: Joza Nicholas; Kroemer Guido; Penninger Josef M
Genetic analysis of the mammalian cell death machinery.
Trends in genetics : TIG 2002;18(3):142-9.
2002: Candé Céline; Cohen Isabelle; Daugas Eric; Ravagnan Luigi; Larochette Nathanael; Zamzami Naoufal; Kroemer Guido
Apoptosis-inducing factor (AIF): a novel caspase-independent death effector released from mitochondria.
Biochimie 2002;84(2-3):215-22.
2002: Belzacq Anne-Sophie; Vieira Helena L A; Kroemer Guido; Brenner Catherine
The adenine nucleotide translocator in apoptosis.
Biochimie 2002;84(2-3):167-76.
2002: Kroemer Guido
Introduction: mitochondrial control of apoptosis.
Biochimie 2002;84(2-3):103-4.
2002: Jan G; Belzacq A-S; Haouzi D; Rouault A; Métivier D; Kroemer G; Brenner C
Propionibacteria induce apoptosis of colorectal carcinoma cells via short-chain fatty acids acting on mitochondria.
Cell death and differentiation 2002;9(2):179-88.
2002: Costantini P; Bruey J-M; Castedo M; Métivier D; Loeffler M; Susin S A; Ravagnan L; Zamzami N; Garrido C; Kroemer Guido
Pre-processed caspase-9 contained in mitochondria participates in apoptosis.
Cell death and differentiation 2002;9(1):82-8.
2001: Daugas E; Candé C; Kroemer G
Erythrocytes: death of a mummy.
Cell death and differentiation 2001;8(12):1131-3.
2001: Belzacq A S; El Hamel C; Vieira H L; Cohen I; Haouzi D; Métivier D; Marchetti P; Brenner C; Kroemer G
Adenine nucleotide translocator mediates the mitochondrial membrane permeabilization induced by lonidamine, arsenite and CD437.
Oncogene 2001;20(52):7579-87.
2001: Ferri K F; Kroemer G
Organelle-specific initiation of cell death pathways.
Nature cell biology 2001;3(11):E255-63.
2001: Kroemer G
Heat shock protein 70 neutralizes apoptosis-inducing factor.
TheScientificWorldJournal 2001;1():590-2.
2001: Castedo M; Ferri K F; Blanco J; Roumier T; Larochette N; Barretina J; Amendola A; Nardacci R; Métivier D; Este J A; Piacentini M; Kroemer G
Human immunodeficiency virus 1 envelope glycoprotein complex-induced apoptosis involves mammalian target of rapamycin/FKBP12-rapamycin-associated protein-mediated p53 phosphorylation.
The Journal of experimental medicine 2001;194(8):1097-110.
2001: Ravagnan L; Gurbuxani S; Susin S A; Maisse C; Daugas E; Zamzami N; Mak T; Jäättelä M; Penninger J M; Garrido C; Kroemer G
Heat-shock protein 70 antagonizes apoptosis-inducing factor.
Nature cell biology 2001;3(9):839-43.
2001: Garrido C; Gurbuxani S; Ravagnan L; Kroemer G
Heat shock proteins: endogenous modulators of apoptotic cell death.
Biochemical and biophysical research communications 2001;286(3):433-42.
2001: Boya P; Roques B; Kroemer G
New EMBO members' review: viral and bacterial proteins regulating apoptosis at the mitochondrial level.
The EMBO journal 2001;20(16):4325-31.
2001: Pardo J; Pérez-Galán P; Gamen S; Marzo I; Monleón I; Kaspar A A; Susín S A; Kroemer G; Krensky A M; Naval J; Anel A
A role of the mitochondrial apoptosis-inducing factor in granulysin-induced apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 2001;167(3):1222-9.
2001: Vieira H L; Belzacq A S; Haouzi D; Bernassola F; Cohen I; Jacotot E; Ferri K F; El Hamel C; Bartle L M; Melino G; Brenner C; Goldmacher V; Kroemer G
The adenine nucleotide translocator: a target of nitric oxide, peroxynitrite, and 4-hydroxynonenal.
Oncogene 2001;20(32):4305-16.
2001: Miramar M D; Costantini P; Ravagnan L; Saraiva L M; Haouzi D; Brothers G; Penninger J M; Peleato M L; Kroemer G; Susin S A
NADH oxidase activity of mitochondrial apoptosis-inducing factor.
The Journal of biological chemistry 2001;276(19):16391-8.
2001: Kroemer G; Krammer P; Piacentini M; Melino G
The European Cell Death Group.
Cell death and differentiation 2001;8(4):438-40.
2001: Joza N; Susin S A; Daugas E; Stanford W L; Cho S K; Li C Y; Sasaki T; Elia A J; Cheng H Y; Ravagnan L; Ferri K F; Zamzami N; Wakeham A; Hakem R; Yoshida H; Kong Y Y; Mak T W; Zúñiga-Pflücker J C; Kroemer G; Penninger J M
Essential role of the mitochondrial apoptosis-inducing factor in programmed cell death.
Nature 2001;410(6828):549-54.
2001: Loeffler M; Daugas E; Susin S A; Zamzami N; Metivier D; Nieminen A L; Brothers G; Penninger J M; Kroemer G
Dominant cell death induction by extramitochondrially targeted apoptosis-inducing factor.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2001;15(3):758-67.
2001: Belzacq A S; Jacotot E; Vieira H L; Mistro D; Granville D J; Xie Z; Reed J C; Kroemer G; Brenner C
Apoptosis induction by the photosensitizer verteporfin: identification of mitochondrial adenine nucleotide translocator as a critical target.
Cancer research 2001;61(4):1260-4.
2001: Jacotot E; Ferri K F; El Hamel C; Brenner C; Druillennec S; Hoebeke J; Rustin P; Métivier D; Lenoir C; Geuskens M; Vieira H L; Loeffler M; Belzacq A S; Briand J P; Zamzami N; Edelman L; Xie Z H; Reed J C; Roques B P; Kroemer G
Control of mitochondrial membrane permeabilization by adenine nucleotide translocator interacting with HIV-1 viral protein rR and Bcl-2.
The Journal of experimental medicine 2001;193(4):509-19.
2001: Ferri K F; Kroemer G
Mitochondria--the suicide organelles.
BioEssays : news and reviews in molecular, cellular and developmental biology 2001;23(2):111-5.
2001: Zamzami N; Kroemer G
The mitochondrion in apoptosis: how Pandora's box opens.
Nature reviews. Molecular cell biology 2001;2(1):67-71.
2001: Zamzami N; Maisse C; Métivier D; Kroemer G
Measurement of membrane permeability and permeability transition of mitochondria.
Methods in cell biology 2001;65():147-58.
2000: Zamzami N; El Hamel C; Maisse C; Brenner C; Muñoz-Pinedo C; Belzacq A S; Costantini P; Vieira H; Loeffler M; Molle G; Kroemer G
Bid acts on the permeability transition pore complex to induce apoptosis.
Oncogene 2000;19(54):6342-50.
2000: Vieira H L; Haouzi D; El Hamel C; Jacotot E; Belzacq A S; Brenner C; Kroemer G
Permeabilization of the mitochondrial inner membrane during apoptosis: impact of the adenine nucleotide translocator.
Cell death and differentiation 2000;7(12):1146-54.
2000: Ferri K F; Jacotot E; Geuskens M; Kroemer G
Apoptosis and karyogamy in syncytia induced by the HIV-1-envelope glycoprotein complex.
Cell death and differentiation 2000;7(11):1137-9.
2000: Ferri K F; Jacotot E; Leduc P; Geuskens M; Ingber D E; Kroemer G
Apoptosis of syncytia induced by the HIV-1-envelope glycoprotein complex: influence of cell shape and size.
Experimental cell research 2000;261(1):119-26.
2000: Ferri K F; Jacotot E; Blanco J; Esté J A; Zamzami N; Susin S A; Xie Z; Brothers G; Reed J C; Penninger J M; Kroemer G
Apoptosis control in syncytia induced by the HIV type 1-envelope glycoprotein complex: role of mitochondria and caspases.
The Journal of experimental medicine 2000;192(8):1081-92.
2000: Rippo M R; Malisan F; Ravagnan L; Tomassini B; Condo I; Costantini P; Susin S A; Rufini A; Todaro M; Kroemer G; Testi R
GD3 ganglioside directly targets mitochondria in a bcl-2-controlled fashion.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(13):2047-54.
2000: Rippo M R; Malisan F; Ravagnan L; Tomassini B; Condò I; Costantini P; Susin S A; Rufini A; Todaro M; Kroemer G; Testi R
GD3 ganglioside as an intracellular mediator of apoptosis.
European cytokine network 2000;11(3):487-8.
2000: Bruey J M; Ducasse C; Bonniaud P; Ravagnan L; Susin S A; Diaz-Latoud C; Gurbuxani S; Arrigo A P; Kroemer G; Solary E; Garrido C
Hsp27 negatively regulates cell death by interacting with cytochrome c.
Nature cell biology 2000;2(9):645-52.
2000: Susin S A; Daugas E; Ravagnan L; Samejima K; Zamzami N; Loeffler M; Costantini P; Ferri K F; Irinopoulou T; Prévost M C; Brothers G; Mak T W; Penninger J; Earnshaw W C; Kroemer G
Two distinct pathways leading to nuclear apoptosis.
The Journal of experimental medicine 2000;192(4):571-80.
2000: Daugas E; Nochy D; Ravagnan L; Loeffler M; Susin S A; Zamzami N; Kroemer G
Apoptosis-inducing factor (AIF): a ubiquitous mitochondrial oxidoreductase involved in apoptosis.
FEBS letters 2000;476(3):118-23.
2000: Costantini P; Jacotot E; Decaudin D; Kroemer G
Mitochondrion as a novel target of anticancer chemotherapy.
Journal of the National Cancer Institute 2000;92(13):1042-53.
2000: Spahr C S; Susin S A; Bures E J; Robinson J H; Davis M T; McGinley M D; Kroemer G; Patterson S D
Simplification of complex peptide mixtures for proteomic analysis: reversible biotinylation of cysteinyl peptides.
Electrophoresis 2000;21(9):1635-50.
2000: Kroemer G; Reed J C
Mitochondrial control of cell death.
Nature medicine 2000;6(5):513-9.
2000: Dallaporta B; Pablo M; Maisse C; Daugas E; Loeffler M; Zamzami N; Kroemer G
Proteasome activation as a critical event of thymocyte apoptosis.
Cell death and differentiation 2000;7(4):368-73.
2000: Daugas E; Susin S A; Zamzami N; Ferri K F; Irinopoulou T; Larochette N; Prévost M C; Leber B; Andrews D; Penninger J; Kroemer G
Mitochondrio-nuclear translocation of AIF in apoptosis and necrosis.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 2000;14(5):729-39.
2000: Loeffler M; Kroemer G
The mitochondrion in cell death control: certainties and incognita.
Experimental cell research 2000;256(1):19-26.
2000: Patterson S D; Spahr C S; Daugas E; Susin S A; Irinopoulou T; Koehler C; Kroemer G
Mass spectrometric identification of proteins released from mitochondria undergoing permeability transition.
Cell death and differentiation 2000;7(2):137-44.
2000: Brenner C; Cadiou H; Vieira H L; Zamzami N; Marzo I; Xie Z; Leber B; Andrews D; Duclohier H; Reed J C; Kroemer G
Bcl-2 and Bax regulate the channel activity of the mitochondrial adenine nucleotide translocator.
Oncogene 2000;19(3):329-36.
2000: Costantini P; Belzacq A S; Vieira H L; Larochette N; de Pablo M A; Zamzami N; Susin S A; Brenner C; Kroemer G
Oxidation of a critical thiol residue of the adenine nucleotide translocator enforces Bcl-2-independent permeability transition pore opening and apoptosis.
Oncogene 2000;19(2):307-14.
2000: Jacotot E; Ravagnan L; Loeffler M; Ferri K F; Vieira H L; Zamzami N; Costantini P; Druillennec S; Hoebeke J; Briand J P; Irinopoulou T; Daugas E; Susin S A; Cointe D; Xie Z H; Reed J C; Roques B P; Kroemer G
The HIV-1 viral protein R induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
The Journal of experimental medicine 2000;191(1):33-46.
2000: Ferri K F; Jacotot E; Blanco J; Esté J A; Kroemer G
Mitochondrial control of cell death induced by HIV-1-encoded proteins.
Annals of the New York Academy of Sciences 2000;926():149-64.
2000: Brenner C; Marzo I; de Araujo Vieira H L; Kroemer G
Purification and liposomal reconstitution of permeability transition pore complex.
Methods in enzymology 2000;322():243-52.
2000: Zamzami N; Métivier D; Kroemer G
Quantitation of mitochondrial transmembrane potential in cells and in isolated mitochondria.
Methods in enzymology 2000;322():208-13.
2000: Susin S A; Larochette N; Geuskens M; Kroemer G
Purification of mitochondria for apoptosis assays.
Methods in enzymology 2000;322():205-8.
2000: Lorenzo H K; Susin S A; Kroemer G
Cytofluorometric quantitation of nuclear apoptosis induced in a cell-free system.
Methods in enzymology 2000;322():198-201.
1999: Vieira H L; Kroemer G
Pathophysiology of mitochondrial cell death control.
Cellular and molecular life sciences : CMLS 1999;56(11-12):971-6.
1999: Marchetti P; Zamzami N; Joseph B; Schraen-Maschke S; Méreau-Richard C; Costantini P; Métivier D; Susin S A; Kroemer G; Formstecher P
The novel retinoid 6-[3-(1-adamantyl)-4-hydroxyphenyl]-2-naphtalene carboxylic acid can trigger apoptosis through a mitochondrial pathway independent of the nucleus.
Cancer research 1999;59(24):6257-66.
1999: Lorenzo H K; Susin S A; Penninger J; Kroemer G
Apoptosis inducing factor (AIF): a phylogenetically old, caspase-independent effector of cell death.
Cell death and differentiation 1999;6(6):516-24.
1999: Larochette N; Decaudin D; Jacotot E; Brenner C; Marzo I; Susin S A; Zamzami N; Xie Z; Reed J; Kroemer G
Arsenite induces apoptosis via a direct effect on the mitochondrial permeability transition pore.
Experimental cell research 1999;249(2):413-21.
1999: Dallaporta B; Marchetti P; de Pablo M A; Maisse C; Duc H T; Métivier D; Zamzami N; Geuskens M; Kroemer G
Plasma membrane potential in thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1999;162(11):6534-42.
1999: de Pablo M A; Susin S A; Jacotot E; Larochette N; Costantini P; Ravagnan L; Zamzami N; Kroemer G
Palmitate induces apoptosis via a direct effect on mitochondria.
Apoptosis : an international journal on programmed cell death 1999;4(2):81-7.
1999: Ravagnan L; Marzo I; Costantini P; Susin S A; Zamzami N; Petit P X; Hirsch F; Goulbern M; Poupon M F; Miccoli L; Xie Z; Reed J C; Kroemer G
Lonidamine triggers apoptosis via a direct, Bcl-2-inhibited effect on the mitochondrial permeability transition pore.
Oncogene 1999;18(16):2537-46.
1999: Susin S A; Lorenzo H K; Zamzami N; Marzo I; Snow B E; Brothers G M; Mangion J; Jacotot E; Costantini P; Loeffler M; Larochette N; Goodlett D R; Aebersold R; Siderovski D P; Penninger J M; Kroemer G
Molecular characterization of mitochondrial apoptosis-inducing factor.
Nature 1999;397(6718):441-6.
1999: Susin S A; Lorenzo H K; Zamzami N; Marzo I; Brenner C; Larochette N; Prévost M C; Alzari P M; Kroemer G
Mitochondrial release of caspase-2 and -9 during the apoptotic process.
The Journal of experimental medicine 1999;189(2):381-94.
1999: Jacotot E; Costantini P; Laboureau E; Zamzami N; Susin S A; Kroemer G
Mitochondrial membrane permeabilization during the apoptotic process.
Annals of the New York Academy of Sciences 1999;887():18-30.
1998: Susin S A; Zamzami N; Kroemer G
Mitochondria as regulators of apoptosis: doubt no more.
Biochimica et biophysica acta 1998;1366(1-2):151-65.
1998: Hirsch T; Dallaporta B; Zamzami N; Susin S A; Ravagnan L; Marzo I; Brenner C; Kroemer G
Proteasome activation occurs at an early, premitochondrial step of thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1998;161(1):35-40.
1998: Hirsch T; Decaudin D; Susin S A; Marchetti P; Larochette N; Resche-Rigon M; Kroemer G
PK11195, a ligand of the mitochondrial benzodiazepine receptor, facilitates the induction of apoptosis and reverses Bcl-2-mediated cytoprotection.
Experimental cell research 1998;241(2):426-34.
1998: Dallaporta B; Hirsch T; Susin S A; Zamzami N; Larochette N; Brenner C; Marzo I; Kroemer G
Potassium leakage during the apoptotic degradation phase.
Journal of immunology (Baltimore, Md. : 1950) 1998;160(11):5605-15.
1998: Marzo I; Susin S A; Petit P X; Ravagnan L; Brenner C; Larochette N; Zamzami N; Kroemer G
Caspases disrupt mitochondrial membrane barrier function.
FEBS letters 1998;427(2):198-202.
1998: Métivier D; Dallaporta B; Zamzami N; Larochette N; Susin S A; Marzo I; Kroemer G
Cytofluorometric detection of mitochondrial alterations in early CD95/Fas/APO-1-triggered apoptosis of Jurkat T lymphoma cells. Comparison of seven mitochondrion-specific fluorochromes.
Immunology letters 1998;61(2-3):157-63.
1998: Zamzami N; Brenner C; Marzo I; Susin S A; Kroemer G
Subcellular and submitochondrial mode of action of Bcl-2-like oncoproteins.
Oncogene 1998;16(17):2265-82.
1998: Marzo I; Brenner C; Zamzami N; Susin S A; Beutner G; Brdiczka D; Rémy R; Xie Z H; Reed J C; Kroemer G
The permeability transition pore complex: a target for apoptosis regulation by caspases and bcl-2-related proteins.
The Journal of experimental medicine 1998;187(8):1261-71.
1998: Hirsch T; Susin S A; Marzo I; Marchetti P; Zamzami N; Kroemer G
Mitochondrial permeability transition in apoptosis and necrosis.
Cell biology and toxicology 1998;14(2):141-5.
1998: Zamzami N; Marzo I; Susin S A; Brenner C; Larochette N; Marchetti P; Reed J; Kofler R; Kroemer G
The thiol crosslinking agent diamide overcomes the apoptosis-inhibitory effect of Bcl-2 by enforcing mitochondrial permeability transition.
Oncogene 1998;16(8):1055-63.
1998: Marzo I; Brenner C; Kroemer G
The central role of the mitochondrial megachannel in apoptosis: evidence obtained with intact cells, isolated mitochondria, and purified protein complexes.
Biomedicine & pharmacotherapy = Biomédecine & pharmacothérapie 1998;52(6):248-51.
1998: Kroemer G; Dallaporta B; Resche-Rigon M
The mitochondrial death/life regulator in apoptosis and necrosis.
Annual review of physiology 1998;60():619-42.
1997: Susin S A; Zamzami N; Larochette N; Dallaporta B; Marzo I; Brenner C; Hirsch T; Petit P X; Geuskens M; Kroemer G
A cytofluorometric assay of nuclear apoptosis induced in a cell-free system: application to ceramide-induced apoptosis.
Experimental cell research 1997;236(2):397-403.
1997: Hirsch T; Marchetti P; Susin S A; Dallaporta B; Zamzami N; Marzo I; Geuskens M; Kroemer G
The apoptosis-necrosis paradox. Apoptogenic proteases activated after mitochondrial permeability transition determine the mode of cell death.
Oncogene 1997;15(13):1573-81.
1997: Kroemer G
Mitochondrial implication in apoptosis. Towards an endosymbiont hypothesis of apoptosis evolution.
Cell death and differentiation 1997;4(6):443-56.
1997: Susin S A; Zamzami N; Castedo M; Daugas E; Wang H G; Geley S; Fassy F; Reed J C; Kroemer G
The central executioner of apoptosis: multiple connections between protease activation and mitochondria in Fas/APO-1/CD95- and ceramide-induced apoptosis.
The Journal of experimental medicine 1997;186(1):25-37.
1997: Hortelano S; Dallaporta B; Zamzami N; Hirsch T; Susin S A; Marzo I; Boscá L; Kroemer G
Nitric oxide induces apoptosis via triggering mitochondrial permeability transition.
FEBS letters 1997;410(2-3):373-7.
1997: Kroemer G
The proto-oncogene Bcl-2 and its role in regulating apoptosis.
Nature medicine 1997;3(6):614-20.
1997: Macho A; Hirsch T; Marzo I; Marchetti P; Dallaporta B; Susin S A; Zamzami N; Kroemer G
Glutathione depletion is an early and calcium elevation is a late event of thymocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1997;158(10):4612-9.
1997: Zamzami N; Hirsch T; Dallaporta B; Petit P X; Kroemer G
Mitochondrial implication in accidental and programmed cell death: apoptosis and necrosis.
Journal of bioenergetics and biomembranes 1997;29(2):185-93.
1997: Hirsch T; Marzo I; Kroemer G
Role of the mitochondrial permeability transition pore in apoptosis.
Bioscience reports 1997;17(1):67-76.
1997: Marchetti P; Decaudin D; Macho A; Zamzami N; Hirsch T; Susin S A; Kroemer G
Redox regulation of apoptosis: impact of thiol oxidation status on mitochondrial function.
European journal of immunology 1997;27(1):289-96.
1997: Decaudin D; Geley S; Hirsch T; Castedo M; Marchetti P; Macho A; Kofler R; Kroemer G
Bcl-2 and Bcl-XL antagonize the mitochondrial dysfunction preceding nuclear apoptosis induced by chemotherapeutic agents.
Cancer research 1997;57(1):62-7.
1996: Macho A; Decaudin D; Castedo M; Hirsch T; Susin S A; Zamzami N; Kroemer G
Chloromethyl-X-Rosamine is an aldehyde-fixable potential-sensitive fluorochrome for the detection of early apoptosis.
Cytometry 1996;25(4):333-40.
1996: Marchetti P; Hirsch T; Zamzami N; Castedo M; Decaudin D; Susin S A; Masse B; Kroemer G
Mitochondrial permeability transition triggers lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(11):4830-6.
1996: Petit P X; Susin S A; Zamzami N; Mignotte B; Kroemer G
Mitochondria and programmed cell death: back to the future.
FEBS letters 1996;396(1):7-13.
1996: Susin S A; Zamzami N; Castedo M; Hirsch T; Marchetti P; Macho A; Daugas E; Geuskens M; Kroemer G
Bcl-2 inhibits the mitochondrial release of an apoptogenic protease.
The Journal of experimental medicine 1996;184(4):1331-41.
1996: Marchetti P; Castedo M; Susin S A; Zamzami N; Hirsch T; Macho A; Haeffner A; Hirsch F; Geuskens M; Kroemer G
Mitochondrial permeability transition is a central coordinating event of apoptosis.
The Journal of experimental medicine 1996;184(3):1155-60.
1996: Ramírez R; Carracedo J; Castedo M; Zamzami N; Kroemer G
CD69-induced monocyte apoptosis involves multiple nonredundant signaling pathways.
Cellular immunology 1996;172(2):192-9.
1996: Castedo M; Hirsch T; Susin S A; Zamzami N; Marchetti P; Macho A; Kroemer G
Sequential acquisition of mitochondrial and plasma membrane alterations during early lymphocyte apoptosis.
Journal of immunology (Baltimore, Md. : 1950) 1996;157(2):512-21.
1996: Marchetti P; Susin S A; Decaudin D; Gamen S; Castedo M; Hirsch T; Zamzami N; Naval J; Senik A; Kroemer G
Apoptosis-associated derangement of mitochondrial function in cells lacking mitochondrial DNA.
Cancer research 1996;56(9):2033-8.
1996: Zamzami N; Marchetti P; Castedo M; Hirsch T; Susin S A; Masse B; Kroemer G
Inhibitors of permeability transition interfere with the disruption of the mitochondrial transmembrane potential during apoptosis.
FEBS letters 1996;384(1):53-7.
1996: Zamzami N; Susin S A; Marchetti P; Hirsch T; Gómez-Monterrey I; Castedo M; Kroemer G
Mitochondrial control of nuclear apoptosis.
The Journal of experimental medicine 1996;183(4):1533-44.
1996: González-García A; Marchetti P; Castedo M; Zamzami N; Tarazona R; Martínez-A C; Kroemer G
Polyethylene glycol-modified IL-2 abrogates superantigen-induced anergy without affecting peripheral clonal deletion in vivo.
Clinical immunology and immunopathology 1996;78(3):215-22.
1996: Rawadi G; Roman-Roman S; Castedo M; Dutilleul V; Susin S; Marchetti P; Geuskens M; Kroemer G
Effects of Mycoplasma fermentans on the myelomonocytic lineage. Different molecular entities with cytokine-inducing and cytocidal potential.
Journal of immunology (Baltimore, Md. : 1950) 1996;156(2):670-8.
1996: Kroemer G; Hirsch F; González-García A; Martínez C
Differential involvement of Th1 and Th2 cytokines in autoimmune diseases.
Autoimmunity 1996;24(1):25-33.
1995: Castedo M; Macho A; Zamzami N; Hirsch T; Marchetti P; Uriel J; Kroemer G
Mitochondrial perturbations define lymphocytes undergoing apoptotic depletion in vivo.
European journal of immunology 1995;25(12):3277-84.
1995: Carracedo J; Ramírez R; Marchetti P; Pintado O C; Baixeras E; Martínez C; Kroemer G
Pertussis toxin-sensitive GTP-binding proteins regulate activation-induced apoptotic cell death of human natural killer cells.
European journal of immunology 1995;25(11):3094-9.
1995: Macho A; Castedo M; Marchetti P; Aguilar J J; Decaudin D; Zamzami N; Girard P M; Uriel J; Kroemer G
Mitochondrial dysfunctions in circulating T lymphocytes from human immunodeficiency virus-1 carriers.
Blood 1995;86(7):2481-7.
1995: Kroemer G; Petit P; Zamzami N; Vayssière J L; Mignotte B
The biochemistry of programmed cell death.
The FASEB journal : official publication of the Federation of American Societies for Experimental Biology 1995;9(13):1277-87.
1995: Zamzami N; Marchetti P; Castedo M; Decaudin D; Macho A; Hirsch T; Susin S A; Petit P X; Mignotte B; Kroemer G
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death.
The Journal of experimental medicine 1995;182(2):367-77.
1995: Zamzami N; Marchetti P; Castedo M; Zanin C; Vayssière J L; Petit P X; Kroemer G
Reduction in mitochondrial potential constitutes an early irreversible step of programmed lymphocyte death in vivo.
The Journal of experimental medicine 1995;181(5):1661-72.
1995: Tarazona R; González-García A; Zamzami N; Marchetti P; Frechin N; Gonzalo J A; Ruiz-Gayo M; van Rooijen N; Martínez C; Kroemer G
Chlorpromazine amplifies macrophage-dependent IL-10 production in vivo.
Journal of immunology (Baltimore, Md. : 1950) 1995;154(2):861-70.
1995: Kroemer G
The pharmacology of T cell apoptosis.
Advances in immunology 1995;58():211-96.
1995: Kroemer G; Zamzami N; Marchetti P; Castedo M
Maintenance of the T lymphocyte pool by inhibition of apoptosis: a novel strategy of immunostimulation?
Current topics in microbiology and immunology 1995;200():223-35.
1994: Ramírez R; Carracedo J; Zamzami N; Castedo M; Kroemer G
Pertussis toxin inhibits activation-induced cell death of human thymocytes, pre-B leukemia cells and monocytes.
The Journal of experimental medicine 1994;180(3):1147-52.
1994: Gonzalo J A; Tarazona R; Schuurman H J; Uytdehaag F; Wick G; Martínez C; Kroemer G
A single injection of Staphylococcus aureus enterotoxin B reduces autoimmunity in MRL/lpr mice.
Clinical immunology and immunopathology 1994;71(2):176-82.
1994: Gonzalo J A; González-García A; Baixeras E; Zamzami N; Tarazona R; Rappuoli R; Martínez C; Kroemer G; Tarazona R; Terezone R
Pertussis toxin interferes with superantigen-induced deletion of peripheral T cells without affecting T cell activation in vivo. Inhibition of deletion and associated programmed cell death depends on ADP-ribosyltransferase activity.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(9):4291-9.
1994: Gonzalo J A; Baixeras E; González-García A; George-Chandy A; Van Rooijen N; Martínez C; Kroemer G
Differential in vivo effects of a superantigen and an antibody targeted to the same T cell receptor. Activation-induced cell death vs passive macrophage-dependent deletion.
Journal of immunology (Baltimore, Md. : 1950) 1994;152(4):1597-608.
1994: Gonzalo J A; González-García A; Kalland T; Hedlung G; Martínez C; Kroemer G
Linomide inhibits programmed cell death of peripheral T cells in vivo.
European journal of immunology 1994;24(1):48-52.
1993: Wick G; Hu Y; Schwarz S; Kroemer G
Immunoendocrine communication via the hypothalamo-pituitary-adrenal axis in autoimmune diseases.
Endocrine reviews 1993;14(5):539-63.
1993: Gonzalo J A; González-García A; Kalland T; Hedlund G; Martínez C; Kroemer G
Linomide, a novel immunomodulator that prevents death in four models of septic shock.
European journal of immunology 1993;23(9):2372-4.
1993: Gonzalo J A; González-García A; Martínez C; Kroemer G
Glucocorticoid-mediated control of the activation and clonal deletion of peripheral T cells in vivo.
The Journal of experimental medicine 1993;177(5):1239-46.
1993: Baixeras E; Kroemer G; Cuende E; Márquez C; Boscá L; Alés Martínez J E; Martínez C
Signal transduction pathways involved in B-cell induction.
Immunological reviews 1993;132():5-47.
1993: Martínez C; Marcos M A; de Alboran I M; Alonso J M; de Cid R; Kroemer G; Coutinho A
Functional double-negative T cells in the periphery express T cell receptor V beta gene products that cause deletion of single-positive T cells.
European journal of immunology 1993;23(1):250-4.
1993: Gonzalo J A; de Alborán I M; Kroemer G
Dissociation of autoaggression and self-superantigen reactivity.
Scandinavian journal of immunology 1993;37(1):1-6.
1993: Kroemer G; Cuende E; Martínez C
Compartmentalization of the peripheral immune system.
Advances in immunology 1993;53():157-216.
1993: Kroemer G; Moreno de Alborán I; Gonzalo J A; Martínez C
Immunoregulation by cytokines.
Critical reviews in immunology 1993;13(2):163-91.
1992: Marquez C; Martinez C; Kroemer G; Bosca L
Protein kinase C isoenzymes display differential affinity for phorbol esters. Analysis of phorbol ester receptors in B cell differentiation.
Journal of immunology (Baltimore, Md. : 1950) 1992;149(8):2560-8.
1992: de Alborán I M; Gonzalo J A; Kroemer G; Leonardo E; Marcos M A; Martínez C
Attenuation of autoimmune disease and lymphocyte accumulation in MRL/lpr mice by treatment with anti-V beta 8 antibodies.
European journal of immunology 1992;22(8):2153-8.
1992: Cuende E; Kroemer G; Alonso J M; Nemazee D; Martínez C; Alés-Martínez J E
Inability of IL-2 and IL-10 to counteract B cell clonal deletion.
Cellular immunology 1992;142(1):94-102.
1992: Gonzalo J A; Moreno de Alborán I; Alés-Martínez J E; Martínez C; Kroemer G
Expansion and clonal deletion of peripheral T cells induced by bacterial superantigen is independent of the interleukin-2 pathway.
European journal of immunology 1992;22(4):1007-11.
1992: De Alborán I M; Gutierrez J C; Gonzalo J A; Andreu J L; Marcos M A; Kroemer G; Martínez C
lpr T cells vaccinate against lupus in MRL/lpr mice.
European journal of immunology 1992;22(4):1089-93.
1992: Alés-Martinez J E; Scott D W; Phipps R P; Casnellie J E; Kroemer G; Martinez C; Pezzi L
Cross-linking of surface IgM or IgD causes differential biological effects in spite of overlap in tyrosine (de)phosphorylation profile.
European journal of immunology 1992;22(3):845-50.
1992: Gonzalo J A; Cuende E; Alés-Martínez J E; Martínez C; Kroemer G
Interleukin-2: a possible trigger for autoimmunity.
International archives of allergy and immunology 1992;97(4):251-7.
1992: Kroemer G; Francese C; Martínez C
The role of interleukin 2 in the development of autoimmune thyroiditis.
International reviews of immunology 1992;9(2):107-23.
1992: Williams O; Gonzalo J A; Martínez C; Kroemer G
Coevolution of hosts and microorganisms: an analysis of the involvement of cytokines in host-parasite interactions.
Memórias do Instituto Oswaldo Cruz 1992;87 Suppl 5():11-21.
1991: Kroemer G; Martínez C
Cytokines and autoimmune disease.
Clinical immunology and immunopathology 1991;61(3):275-95.
1991: Alonso J M; Rodriguez J; Viñuela E; Kroemer G; Martínez C
Highly efficient expression of proteins encoded by recombinant vaccinia virus in lymphocytes.
Scandinavian journal of immunology 1991;34(5):619-26.
1991: Bárcena A; Sánchez M J; de la Pompa J L; Toribio M L; Kroemer G; Martínez-A C
Involvement of the interleukin 4 pathway in the generation of functional gamma delta T cells from human pro-T cells.
Proceedings of the National Academy of Sciences of the United States of America 1991;88(17):7689-93.
1991: Kroemer G; de Cid R; Moreno de Alborán I; Gonzalo J A; Iglesias A; Martínez C; Gutierrez-Ramos J C
Immunological self-tolerance: an analysis employing cytokines or cytokine receptors encoded by transgenes or a recombinant vaccinia virus.
Immunological reviews 1991;122():173-204.
1991: Andreu-Sánchez J L; Moreno de Alborán I M; Marcos M A; Sánchez-Movilla A; Martínez-A C; Kroemer G
Interleukin 2 abrogates the nonresponsive state of T cells expressing a forbidden T cell receptor repertoire and induces autoimmune disease in neonatally thymectomized mice.
The Journal of experimental medicine 1991;173(6):1323-9.
1991: Bárcena A; Toribio M L; Gutierrez-Ramos J C; Kroemer G; Martínez C
Interplay between IL-2 and IL-4 in human thymocyte differentiation: antagonism or agonism.
International immunology 1991;3(5):419-25.
1991: Kroemer G; Andreu J L; Gonzalo J A; Gutierrez-Ramos J C; Martínez C
Interleukin-2, autotolerance, and autoimmunity.
Advances in immunology 1991;50():147-235.
1991: Kroemer G; Helmberg A; Bernot A; Auffray C; Kofler R
Evolutionary relationship between human and mouse immunoglobulin kappa light chain variable region genes.
Immunogenetics 1991;33(1):42-9.
1990: Helmberg A; Fässler R; Geley S; Jöhrer K; Kroemer G; Böck G; Kofler R
Glucocorticoid-regulated gene expression in the immune system. Analysis of glucocorticoid-regulated transcripts from the mouse macrophage-like cell line P388D1.
Journal of immunology (Baltimore, Md. : 1950) 1990;145(12):4332-7.
1990: Gutierrez-Ramos J C; Andreu J L; Moreno de Alboran I; Rodriguez J; Leonardo E; Kroemer G; Marcos M A; Martinez C
Insights into autoimmunity: from classical models to current perspectives.
Immunological reviews 1990;118():73-101.
1990: Brezinschek H P; Faessler R; Klocker H; Kroemer G; Sgonc R; Dietrich H; Jakober R; Wick G
Analysis of the immune-encodrine feedback loop in the avian system and its alteration in chickens with spontaneous autoimmune thyroiditis.
European journal of immunology 1990;20(10):2155-9.
1990: Kroemer G; Gastinel L N; Neu N; Auffray C; Wick G
How many genes code for organ-specific autoimmunity?
Autoimmunity 1990;6(3):215-33.
1990: Wick G; Dietrich H; Kroemer G; Brezinschek H P; Faessler R; Schuurs A H
Spontaneous autoimmune thyroiditis: new therapeutic strategies.
Immunology series 1990;52():191-211.
1989: Kroemer G; Neu N; Kuehr T; Dietrich H; Fässler R; Hala K; Wick G
Immunogenetic analysis of spontaneous autoimmune thyroiditis of obese strain chickens.
Clinical immunology and immunopathology 1989;52(2):202-13.
1989: Penninger J; Klima J; Kroemer G; Dietrich H; Hala K; Wick G
Intra-thymic nurse cell lymphocytes can induce a graft-versus-host reaction with high efficiency.
Developmental and comparative immunology 1989;13(4):313-27.
1989: Wick G; Brezinschek H P; Hála K; Dietrich H; Wolf H; Kroemer G
The obese strain of chickens: an animal model with spontaneous autoimmune thyroiditis.
Advances in immunology 1989;47():433-500.
1989: Strohal R; Helmberg A; Kroemer G; Kofler R
Mouse Vk gene classification by nucleic acid sequence similarity.
Immunogenetics 1989;30(6):475-93.
1988: Kroemer G; Faessler R; Hála K; Boeck G; Schauenstein K; Brezinschek H P; Neu N; Dietrich H; Jakober R; Wick G
Genetic analysis of extrathyroidal features of Obese strain (OS) chickens with spontaneous autoimmune thyroiditis.
European journal of immunology 1988;18(10):1499-505.
1988: Kroemer G; Klocker H; Faessler R; Sachsenmaier W; Wick G
Decreased level of thymidine in the serum of obese strain (OS) chickens with spontaneous autoimmune thyroiditis.
Immunological investigations 1988;17(3):243-56.
1988: Kroemer G; Faessler R; Wick G
Disturbed immune regulation in spontaneous autoimmune thyroiditis.
Concepts in immunopathology 1988;5():106-29.
1988: Kroemer G; Boeck G; Schauenstein K; Hilchenbach M; Faessler R; Wick G
T cell hyperproliferation in autoimmunity prone obese strain (OS) chickens is independent of abnormal mitogen binding in vitro and can be demonstrated in vivo.
Developmental and comparative immunology 1988;12(2):363-73.
1987: Kroemer G; Faessler R; Strohal R; Wick G; Kofler R
Evidence for a new murine immunoglobulin heavy chain variable region gene family.
Immunological investigations 1987;16(2):107-16.
1987: Strohal R; Kroemer G; Wick G; Kofler R
Complete variable region sequence of a nonfunctionally rearranged kappa light chain transcribed in the nonsecretor P3-X63-Ag8.653 myeloma cell line.
Nucleic acids research 1987;15(6):2771.

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