FIND

researchers

DISCOVER

relevant articles

PROMOTE

your research

now for free

Heyo Kroemer

Research Profile

Chemicals & Drugs

Physiology

Co-author Network

Publications

TOP 3
Julia Mayerle; Matthias Nauck; Marjolein J Peters; Holger Prokisch; Fernando Rivadeneira; Claudia Schurmann; Ivo Steinmetz; Lisette Stolk; Alexander Teumer; Andre G Uitterlinden; Joyce B J van Meurs; Uwe Völker; Henry Völzke; Frank-Ulrich Weiss; Martin Zenker; Kathrin Zimmermann; Lisette G Capelle; Annemarie C de Vries; Caroline M den Hoed; Florian Ernst; Sybille Gruska; Albert Hofman; Georg Homuth; Heyo K Kroemer; Markus M Lerch; Ernst Kuipers
Identification of genetic loci associated with Helicobacter pylori serologic status.
W Lieb; H J Grabe; Heyo K Kroemer
[Research projects for implementation of individualized medicine].
Sabine Ameling; Marcus Dörr; Elke Hammer; Lars R Herda; Reinhard Kandolf; Karin Klingel; Heyo K Kroemer; Leif Steil; Alexander Teumer; Christiane Trimpert; Uwe Völker; Stephan B Felix
Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy.

Register for free to view:

Visualized networks:

See your personal network in
sophisticated graphical views

GeoTargeted Searches:

Locate experts around the world
and connect with global collaborators

Research Profiles:

See the research activity
of experts around the globe

Geonetwork of Heyo Kroemer (preview)

Cities where this author has publications
Cities where co-authors of this author have publications

Flash Player Required

All Publications

2013: Julia Mayerle; Matthias Nauck; Marjolein J Peters; Holger Prokisch; Fernando Rivadeneira; Claudia Schurmann; Ivo Steinmetz; Lisette Stolk; Alexander Teumer; Andre G Uitterlinden; Joyce B J van Meurs; Uwe Völker; Henry Völzke; Frank-Ulrich Weiss; Martin Zenker; Kathrin Zimmermann; Lisette G Capelle; Annemarie C de Vries; Caroline M den Hoed; Florian Ernst; Sybille Gruska; Albert Hofman; Georg Homuth; Heyo K Kroemer; Markus M Lerch; Ernst Kuipers
Identification of genetic loci associated with Helicobacter pylori serologic status.
JAMA : the journal of the American Medical Association 2013;309(18):1912-20.
2013: W Lieb; H J Grabe; Heyo K Kroemer
[Research projects for implementation of individualized medicine].
Deutsche medizinische Wochenschrift (1946) 2013;138(13):665-6.
2013: Sabine Ameling; Marcus Dörr; Elke Hammer; Lars R Herda; Reinhard Kandolf; Karin Klingel; Heyo K Kroemer; Leif Steil; Alexander Teumer; Christiane Trimpert; Uwe Völker; Stephan B Felix
Myocardial gene expression profiles and cardiodepressant autoantibodies predict response of patients with dilated cardiomyopathy to immunoadsorption therapy.
European heart journal 2013;34(9):666-75.
2013: Christiane Kunert-Keil; Martin Landsberger; Felix Niessner; Heinrich Brinkmeier; Stephan B Felix; Franziska Jantzen; Heyo K Kroemer; Jörg Peters
Molecular changes in the early phase of renin-dependent cardiac hypertrophy in hypertensive cyp1a1ren-2 transgenic rats.
Journal of the renin-angiotensin-aldosterone system : JRAAS 2013;14(1):41-50.
2013: Katrin Hegenscheid; Norbert Hosten; Heyo K Kroemer; Jens-Peter Kühn; Carsten Oliver Schmidt; Rebecca Seipel; Henry Völzke; Reiner Biffar; Ralf Puls
Potentially relevant incidental findings on research whole-body MRI in the general adult population: frequencies and management.
European radiology 2013;23(3):816-26.
2013: Katrin Sternberg; Werner Weitschies; Niels Grabow; Claus Harder; Hüseyin Ince; Heyo K Kroemer; Svea Petersen; Klaus-Peter Schmitz
Advances in coronary stent technology--active drug-loaded stent surfaces for prevention of restenosis and improvement of biocompatibility.
Current pharmaceutical biotechnology 2013;14(1):76-90.
2013: Anne Seidlitz; Beatrice Semmling; Katrin Sternberg; Heyo K Kroemer; Stefan Nagel; Werner Weitschies
In vitro dissolution testing of drug-eluting stents.
Current pharmaceutical biotechnology 2013;14(1):67-75.
2012: Anna Koenen; Heyo K Kroemer; Werner Siegmund; Markus Keiser; Kathleen Köck; Markus Grube
Steroid hormones specifically modify the activity of organic anion transporting polypeptides.
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences 2012;47(4):774-80.
2012: Alexander Riad; Kerstin Weitmann; Marcus Dörr; Klaus Empen; Marcus Grube; Lars R Herda; Wolfgang Hoffmann; Astrid Hummel; Reinhard Kandolf; Arne Kieback; Karin Klingel; Heyo K Kroemer; Henriette Meyer zu Schwabedissen; Matthias Nauck; Marcus Reinthaler; Stephan B Felix
Variants of Toll-like receptor 4 predict cardiac recovery in patients with dilated cardiomyopathy.
The Journal of biological chemistry 2012;287(32):27236-43.
2012: Henriette Meyer zu Schwabedissen; Christiane Modess; A Nassif; M Nauck; E T Ogburn; Stefan Oswald; C Bresser; Z Desta; Heyo K Kroemer; Dieter Lütjohann; M Marinova; C Spielhagen; Werner Siegmund
Compartment-specific gene regulation of the CAR inducer efavirenz in vivo.
Clinical pharmacology and therapeutics 2012;92(1):103-11.
2012: Janka Reimer; Uwe Völker; Sabine Ameling; Sandra Bien; Joachim Boos; Elke Hammer; Georg Hempel; Heyo K Kroemer; Christoph A Ritter
Antineoplastic agent busulfan regulates a network of genes related to coagulation and fibrinolysis.
European journal of clinical pharmacology 2012;68(6):923-35.
2012: Bernard Prendergast; Nicole Probst-Hensch; Ernst Th Rietschel; Hartmut Rütten; Caroline Steingen; Alain Tedgui; Wiek van Gilst; Heyo K Kroemer; Anne Lücke; Heini Murer; Eike Nagel; Ludwig Neyses; Joep Perk; Leslie T Coope; Harry Crijns; Thomas Eschenhagen; Elisabeth Falkenstein; Ulrich Fölsch; Sigrun Halvorsen; Stefan Janssens; Eero Jokinen; Steen Dalby Kristensen
The German Centre for Cardiovascular Research.
European heart journal 2012;33(9):1033-36,1036a.
2012: J Hussner; Heyo K Kroemer; Juliane Niessen; Christoph A Ritter; H W S Schroeder; M Schwebe; Leif Steil; Uwe Völker; S Ameling; Elke Hammer; S Herzog; Sandra Bien
Regulation of interferon-inducible proteins by doxorubicin via interferon γ-Janus tyrosine kinase-signal transducer and activator of transcription signaling in tumor cells.
Molecular pharmacology 2012;81(5):679-88.
2012: Gabriele Jedlitschky; Andreas Greinacher; Heyo K Kroemer
Transporters in human platelets: physiologic function and impact for pharmacotherapy.
Blood 2012;119(15):3394-402.
2012: Stefan Oswald; D Runge; A Ulrich; Z Desta; A Hubeny; J Jia; M Keiser; Heyo K Kroemer; Dieter Lütjohann; M Marinova; Henriette Meyer zu Schwabedissen; Christiane Modess; Jörg Mostertz; A Nassif; E T Ogburn; Werner Siegmund
Impact of efavirenz on intestinal metabolism and transport: insights from an interaction study with ezetimibe in healthy volunteers.
Clinical pharmacology and therapeutics 2012;91(3):506-13.
2012: Florian Custodis; Peter Fries; Markus Grube; Heyo K Kroemer; Andreas Müller; Christoph Stamm; Michael Böhm; Ulrich Laufs
Heart rate reduction by ivabradine improves aortic compliance in apolipoprotein E-deficient mice.
Journal of vascular research 2012;49(5):432-40.
2012: Katrin Sternberg; Conny Tuemmler; Werner Weitschies; Robert Begunk; Niels Grabow; Matthias Gratz; Petra Hildebrandt; Georg Homuth; Kathleen Koeck; Marian Loebler; Joerg Mostertz; Klaus-Peter Schmitz; Anne Seidlitz; Beatrice Semmling; Heyo K Kroemer
Magnesium used in bioabsorbable stents controls smooth muscle cell proliferation and stimulates endothelial cells in vitro.
Journal of biomedical materials research. Part B, Applied biomaterials 2012;100(1):41-50.
2011: Anna Koenen; Heyo K Kroemer; Markus Grube; Henriette E Meyer zu Schwabedissen
Current understanding of hepatic and intestinal OATP-mediated drug-drug interactions.
Expert review of clinical pharmacology 2011;4(6):729-42.
2011: Krishnatej Nishtala; Truong Q Phong; Manuela G Salazar; Martina Sauter; Leif Steil; Uwe Völker; Stephan B Felix; Reinhard Kandolf; Karin Klingel; Heyo K Kroemer; Elke Hammer
Virus-induced dilated cardiomyopathy is characterized by increased levels of fibrotic extracellular matrix proteins and reduced amounts of energy-producing enzymes.
Proteomics 2011;11(22):4310-20.
2011: Jette Peters; Monica Venner; Wiebke Block; Johanna Freyer; Markus Grube; Heyo K Kroemer; Marc Lämmer; Dieter Lütjohann; Stefan Oswald; Werner Siegmund
Oral absorption of clarithromycin is nearly abolished by chronic comedication of rifampicin in foals.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(9):1643-9.
2011: Thomas Budde; Stephan B Felix; Sandra Bien; Jeanette Haney; Gabriele Jedlitschky; Heyo K Kroemer; Alexander Riad; Matthias Schwebe; Alexander Staudt; Carsten Tschöpe; Markus Grube
Acute exposure to doxorubicin results in increased cardiac P-glycoprotein expression.
Journal of pharmaceutical sciences 2011;100(9):3951-8.
2011: Markus Grube; Sabine Ameling; Michel Noutsias; Kathleen Köck; Ivonne Triebel; Karina Bonitz; Konrad Meissner; Gabriele Jedlitschky; Lars R Herda; Markus Reinthaler; Maria Rohde; Wolfgang Hoffmann; Uwe Kühl; Heinz-Peter Schultheiss; Uwe Völker; Stephan B Felix; Karin Klingel; Reinhard Kandolf; Heyo K Kroemer
Selective regulation of cardiac organic cation transporter novel type 2 (OCTN2) in dilated cardiomyopathy.
The American journal of pathology 2011;178(6):2547-59.
2011: Karsten Suhre; Henri Wallaschofski; Johannes Raffler; Nele Friedrich; Robin Haring; Kathrin Michael; Christina Wasner; Alexander Krebs; Florian Kronenberg; David Chang; Christa Meisinger; H-Erich Wichmann; Wolfgang Hoffmann; Henry Völzke; Uwe Völker; Alexander Teumer; Reiner Biffar; Thomas Kocher; Stephan B Felix; Thomas Illig; Heyo K Kroemer; Christian Gieger; Werner Römisch-Margl; Matthias Nauck
A genome-wide association study of metabolic traits in human urine.
Nature genetics 2011;43(6):565-9.
2011: Elke Hammer; Lars R Herda; Reinhard Kandolf; Karin Klingel; Heyo K Kroemer; Alexander Staudt; Leif Steil; Christiane Trimpert; Sabine Ameling; Katrin Darm; Marcus Dörr; Stephan B Felix; Michelle Goritzka; Uwe Völker
Characterization of the human myocardial proteome in inflammatory dilated cardiomyopathy by label-free quantitative shotgun proteomics of heart biopsies.
Journal of proteome research 2011;10(5):2161-71.
2011: Anne Seidlitz; Stefan Nagel; Beatrice Semmling; Niels Grabow; Heiner Martin; Volkmar Senz; Claus Harder; Katrin Sternberg; Klaus-Peter Schmitz; Heyo K Kroemer; Werner Weitschies
Examination of drug release and distribution from drug-eluting stents with a vessel-simulating flow-through cell.
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft für Pharmazeutische Verfahrenstechnik e.V 2011;78(1):36-48.
2011: Frank Luderer; Marian Löbler; Henning W Rohm; Christian Gocke; Katharina Wulf; Kathleen Köck; Heyo K Kroemer; Werner Weitschies; Klaus-Peter Schmitz; Katrin Sternberg
Biodegradable sirolimus-loaded poly(lactide) nanoparticles as drug delivery system for the prevention of in-stent restenosis in coronary stent application.
Journal of biomaterials applications 2011;25(8):851-75.
2011: Dan Mark Roden; Russell A Wilke; Heyo K Kroemer; C Michael Stein
Pharmacogenomics: the genetics of variable drug responses.
Circulation 2011;123(15):1661-70.
2011: Oliver Adam; Katharina Theobald; Daniel Lavall; Markus Grube; Heyo K Kroemer; Sabine Ameling; Hans-Joachim Schäfers; Michael Böhm; Ulrich Laufs
Increased lysyl oxidase expression and collagen cross-linking during atrial fibrillation.
Journal of molecular and cellular cardiology 2011;50(4):678-85.
2011: Matthias Schwab; E Schaeffeler; U M Zanger; Hiltrud Brauch; Heyo K Kroemer
[Pharmacogenomics: hype or hope?].
Deutsche medizinische Wochenschrift (1946) 2011;136(10):461-7.
2011: Dieter Rosskopf; Christian Schwahn; F Neumann; A Bornhorst; Christian Rimmbach; M Mischke; S Wolf; Ingrid Geissler; Thomas Kocher; Hans Joergen Grabe; Matthias Nauck; J Hebebrand; Heyo K Kroemer; Nele Friedrich; Henry Völzke; Henri Wallaschofski
The growth hormone--IGF-I axis as a mediator for the association between FTO variants and body mass index: results of the Study of Health in Pomerania.
International journal of obesity (2005) 2011;35(3):364-72.
2011: Markus Schürks; Franziska A Neumann; Christof Kessler; Hans-Christoph Diener; Heyo K Kroemer; Tobias Kurth; Henry Völzke; Dieter Rosskopf
MTHFR 677C>T polymorphism and cluster headache.
Headache 2011;51(2):201-7.
2011: Robin Haring; Sebastian E Baumeister; Henry Völzke; Marcus Dörr; Stephan B Felix; Heyo K Kroemer; Matthias Nauck; Henri Wallaschofski
Prospective association of low total testosterone concentrations with an adverse lipid profile and increased incident dyslipidemia.
European journal of cardiovascular prevention and rehabilitation : official journal of the European Society of Cardiology, Working Groups on Epidemiology & Prevention and Cardiac Rehabilitation and Exercise Physiology 2011;18(1):86-96.
2011: Anja Brenn; Andrea Fischer; Markus Grube; Gabriele Jedlitschky; Heyo K Kroemer; Michele Peters; Rolf W Warzok; Silke Vogelgesang
Beta-Amyloid Downregulates MDR1-P-Glycoprotein (Abcb1) Expression at the Blood-Brain Barrier in Mice.
International journal of Alzheimer's disease 2011;2011():690121.
2011: Robin Haring; Matthias Nauck; Henry Völzke; Karlhans Endlich; Uwe Lendeckel; Nele Friedrich; Marcus Dörr; Rainer Rettig; Heyo K Kroemer; Henri Wallaschofski
Low serum testosterone is associated with increased mortality in men with stage 3 or greater nephropathy.
American journal of nephrology 2011;33(3):209-17.
2011: Russ B Altman; Heyo K Kroemer; Catherine A McCarty; Mark J Ratain; Dan Roden
Pharmacogenomics: will the promise be fulfilled?
Nature reviews. Genetics 2011;12(1):69-73.
2011: Henriette E Meyer zu Schwabedissen; Heyo K Kroemer
In vitro and in vivo evidence for the importance of breast cancer resistance protein transporters (BCRP/MXR/ABCP/ABCG2).
Handbook of experimental pharmacology 2011;(201):325-71.
2011: Praveen K Nambaru; Tobias Hübner; Kathleen Köck; Steffen Mews; Markus Grube; Léa Payen; Jérôme Guitton; Matthias Sendler; Gabriele Jedlitschky; Christian Rimmbach; Dieter Rosskopf; Dariusz W Kowalczyk; Heyo K Kroemer; Frank U Weiss; Julia Mayerle; Markus M Lerch; Christoph A Ritter
Drug efflux transporter multidrug resistance-associated protein 5 affects sensitivity of pancreatic cancer cell lines to the nucleoside anticancer drug 5-fluorouracil.
Drug metabolism and disposition: the biological fate of chemicals 2011;39(1):132-9.
2010: Sandra Bien; Christian Rimmbach; H Neumann; Juliane Niessen; E Reimer; Christoph A Ritter; D Rosskopf; J Cinatl; M Michaelis; H W S Schroeder; Heyo K Kroemer
Doxorubicin-induced cell death requires cathepsin B in HeLa cells.
Biochemical pharmacology 2010;80(10):1466-77.
2010: Henriette E Meyer Zu Schwabedissen; Kerstin Böttcher; Amarjit Chaudhry; Heyo K Kroemer; Erin G Schuetz; Richard B Kim
Liver X receptor α and farnesoid X receptor are major transcriptional regulators of OATP1B1.
Hepatology (Baltimore, Md.) 2010;52(5):1797-807.
2010: Gabriele Jedlitschky; Silke Vogelgesang; Heyo K Kroemer
MDR1-P-glycoprotein (ABCB1)-mediated disposition of amyloid-β peptides: implications for the pathogenesis and therapy of Alzheimer's disease.
Clinical pharmacology and therapeutics 2010;88(4):441-3.
2010: Marcus Dörr; Carsten Oliver Schmidt; Thomas Spielhagen; Alexa Bornhorst; Katharina Hentschel; Christina Franz; Klaus Empen; Thomas Kocher; Scott R Diehl; Heyo K Kroemer; Henry Völzke; Ralf Ewert; Stephan B Felix; Dieter Rosskopf
β-blocker therapy and heart rate control during exercise testing in the general population: role of a common G-protein β-3 subunit variant.
Pharmacogenomics 2010;11(9):1209-21.
2010: Mirko Leonhardt; Markus Keiser; Stefan Oswald; Jens Kühn; Jia Jia; Markus Grube; Heyo K Kroemer; Werner Siegmund; Werner Weitschies
Hepatic uptake of the magnetic resonance imaging contrast agent Gd-EOB-DTPA: role of human organic anion transporters.
Drug metabolism and disposition: the biological fate of chemicals 2010;38(7):1024-8.
2010: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Hirotaka Kawakami; Junichi Kamiie; Sumio Ohtsuki; Hansjörg Schwertz; Sandra Bien; Katharina Starke; Christoph Ritter; Ulrike Strobel; Andreas Greinacher; Tetsuya Terasaki; Heyo K Kroemer
Expression of ABC-type transport proteins in human platelets.
Pharmacogenetics and genomics 2010;20(6):396-400.
2010: Elke Hammer; Truong Quoc Phong; Leif Steil; Karin Klingel; Manuela Gesell Salazar; Joerg Bernhardt; Reinhard Kandolf; Heyo K Kroemer; Stephan B Felix; Uwe Völker
Viral myocarditis induced by Coxsackievirus B3 in A.BY/SnJ mice: analysis of changes in the myocardial proteome.
Proteomics 2010;10(9):1802-18.
2010: Kathleen Köck; Anna Koenen; Bernd Giese; Martin Fraunholz; Karen May; Werner Siegmund; Elke Hammer; Uwe Völker; Gabriele Jedlitschky; Heyo K Kroemer; Markus Grube
Rapid modulation of the organic anion transporting polypeptide 2B1 (OATP2B1, SLCO2B1) function by protein kinase C-mediated internalization.
The Journal of biological chemistry 2010;285(15):11336-47.
2010: A Staudt; L R Herda; Christiane Trimpert; L Lubenow; Martin Landsberger; Marcus Dörr; Astrid Hummel; L G Eckerle; D Beug; C Müller; W Hoffmann; K Weitmann; Karin Klingel; Reinhard Kandolf; Heyo K Kroemer; Andreas Greinacher; Stephan B Felix
Fcgamma-receptor IIa polymorphism and the role of immunoadsorption in cardiac dysfunction in patients with dilated cardiomyopathy.
Clinical pharmacology and therapeutics 2010;87(4):452-8.
2010: Henriette E Meyer zu Schwabedissen; Celine Verstuyft; Heyo K Kroemer; Laurent Becquemont; Richard B Kim
Human multidrug and toxin extrusion 1 (MATE1/SLC47A1) transporter: functional characterization, interaction with OCT2 (SLC22A2), and single nucleotide polymorphisms.
American journal of physiology. Renal physiology 2010;298(4):F997-F1005.
2010: Juliane Niessen; Gabriele Jedlitschky; Andreas Greinacher; Heyo K Kroemer
Isolation of platelet granules.
Current protocols in cell biology / editorial board, Juan S. Bonifacino ... [et al.] 2010;Chapter 3():Unit 3.35.
2010: Gabriele Jedlitschky; Marco Cattaneo; Lena E Lubenow; Dieter Rosskopf; Anna Lecchi; Andrea Artoni; Giovanna Motta; Juliane Niessen; Heyo K Kroemer; Andreas Greinacher
Role of MRP4 (ABCC4) in platelet adenine nucleotide-storage: evidence from patients with delta-storage pool deficiencies.
The American journal of pathology 2010;176(3):1097-103.
2010: Oliver Adam; Daniel Lavall; Katharina Theobald; Mathias Hohl; Markus Grube; Sabine Ameling; Mark A Sussman; Stephan Rosenkranz; Heyo K Kroemer; Hans-Joachim Schäfers; Michael Böhm; Ulrich Laufs
Rac1-induced connective tissue growth factor regulates connexin 43 and N-cadherin expression in atrial fibrillation.
Journal of the American College of Cardiology 2010;55(5):469-80.
2010: Monica Venner; Jette Peters; Nina Höhensteiger; Birthe Schock; Alexa Bornhorst; Markus Grube; Ulrike Adam; Eberhard Scheuch; Werner Weitschies; Dieter Rosskopf; Heyo K Kroemer; Werner Siegmund
Concentration of the macrolide antibiotic tulathromycin in broncho-alveolar cells is influenced by comedication of rifampicin in foals.
Naunyn-Schmiedeberg's archives of pharmacology 2010;381(2):161-9.
2010: Dieter Rosskopf; Henriette Meyer zu Schwabedissen; Heyo K Kroemer; Werner Siegmund
[Pharmacogenomics in routine medical care].
Deutsche medizinische Wochenschrift (1946) 2010;135(4):133-44; quiz 145-6.
2010: Heyo K Kroemer; Henriette Meyer zu Schwabedissen
A piece in the puzzle of personalized medicine.
Clinical pharmacology and therapeutics 2010;87(1):19-20.
2010: Elke Hammer; Sandra Bien; Manuela Gesell Salazar; Leif Steil; Christian Scharf; Petra Hildebrandt; Henry W S Schroeder; Heyo K Kroemer; Uwe Völker; Christoph A Ritter
Proteomic analysis of doxorubicin-induced changes in the proteome of HepG2cells combining 2-D DIGE and LC-MS/MS approaches.
Proteomics 2010;10(1):99-114.
2009: Henry Völzke; Alexa Bornhorst; Christian Rimmbach; Holger Petersenn; Ingrid Geissler; Matthias Nauck; Henri Wallaschofski; Heyo K Kroemer; Dieter Rosskopf
Common variants in the G protein beta3 subunit gene and thyroid disorders in a formerly iodine-deficient population.
Thyroid : official journal of the American Thyroid Association 2009;19(10):1115-9.
2009: Lena Oevermann; Jan Scheitz; Katharina Starke; Kathleen Köck; Thomas Kiefer; Gottfried Dölken; Juliane Niessen; Andreas Greinacher; Werner Siegmund; Marek Zygmunt; Heyo K Kroemer; Gabriele Jedlitschky; Christoph A Ritter
Hematopoietic stem cell differentiation affects expression and function of MRP4 (ABCC4), a transport protein for signaling molecules and drugs.
International journal of cancer. Journal international du cancer 2009;124(10):2303-11.
2009: Mike Ufer; Igor Mosyagin; Hiltrud Muhle; Thies Jacobsen; Sierk Haenisch; Robert Häsler; Frank Faltraco; Cornelia Remmler; Sarah von Spiczak; Heyo K Kroemer; Uwe Runge; Rainer Boor; Ulrich Stephani; Ingolf Cascorbi
Non-response to antiepileptic pharmacotherapy is associated with the ABCC2 -24C>T polymorphism in young and adult patients with epilepsy.
Pharmacogenetics and genomics 2009;19(5):353-62.
2009: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Sandra Bien; Hansjörg Schwertz; Sumio Ohtsuki; Hirotaka Kawakami; Junichi Kamiie; Stefan Oswald; Katharina Starke; Ulrike Strobel; Werner Siegmund; Dieter Rosskopf; Andreas Greinacher; Tetsuya Terasaki; Heyo K Kroemer
Human platelets express organic anion-transporting peptide 2B1, an uptake transporter for atorvastatin.
Drug metabolism and disposition: the biological fate of chemicals 2009;37(5):1129-37.
2009: Olaf Grisk; Antje C Steinbach; Sabine Ciecholewski; Torsten Schlüter; Ingrid Klöting; Helmut Schmidt; Eike Dazert; Elke Schaeffeler; Leif Steil; Stefan Gauer; Gabriele Jedlitschky; Matthias Schwab; Gerd Geisslinger; Ingeborg A Hauser; Uwe Völker; Heyo K Kroemer; Rainer Rettig
Multidrug resistance-related protein 2 genotype of the donor affects kidney graft function.
Pharmacogenetics and genomics 2009;19(4):276-88.
2009: Y Guo; Kathleen Köck; Christoph A Ritter; Zhe-Sheng Chen; Markus Grube; Gabriele Jedlitschky; Thomas Illmer; Mary Ayres; James F Beck; Werner Siegmund; Gerhard Ehninger; Varsha Gandhi; Heyo K Kroemer; Gary Kruh; Markus Schaich
Expression of ABCC-type nucleotide exporters in blasts of adult acute myeloid leukemia: relation to long-term survival.
Clinical cancer research : an official journal of the American Association for Cancer Research 2009;15(5):1762-9.
2009: D Rosskopf; Heyo K Kroemer; Werner Siegmund
[Pharmacokinetic problems in clinical practice: role of drug transporters].
Deutsche medizinische Wochenschrift (1946) 2009;134(8):345-56; quiz 357-60.
2009: Alexander Riad; Sandra Bien; Dirk Westermann; Peter M Becher; Komal Loya; Ulf Landmesser; Heyo K Kroemer; Heinz-Peter Schultheiss; Carsten Tschöpe
Pretreatment with statin attenuates the cardiotoxicity of Doxorubicin in mice.
Cancer research 2009;69(2):695-9.
2008: Victor Agmo Hernández; Juliane Niessen; Falk Harnisch; Stephan Block; Andreas Greinacher; Heyo K Kroemer; Christiane A Helm; Fritz Scholz
The adhesion and spreading of thrombocyte vesicles on electrode surfaces.
Bioelectrochemistry (Amsterdam, Netherlands) 2008;74(1):210-6.
2008: Anne Neubert; Katrin Sternberg; Stefan Nagel; Claus Harder; Klaus-Peter Schmitz; Heyo K Kroemer; Werner Weitschies
Development of a vessel-simulating flow-through cell method for the in vitro evaluation of release and distribution from drug-eluting stents.
Journal of controlled release : official journal of the Controlled Release Society 2008;130(1):2-8.
2008: Martin Landsberger; Alexander Staudt; Sangita Choudhury; Christiane Trimpert; Lars R Herda; Karin Klingel; Reinhard Kandolf; Heinz-Peter Schultheiss; Heyo K Kroemer; Uwe Völker; Stephan B Felix
Potential role of antibodies against cardiac Kv channel-interacting protein 2 in dilated cardiomyopathy.
American heart journal 2008;156(1):92-99.e2.
2008: Jürgen Sonnemann; Isabel Hüls; Michael Sigler; Chithra D Palani; Le Thi Thu Hong; Uwe Völker; Heyo K Kroemer; James F Beck
Histone deacetylase inhibitors and aspirin interact synergistically to induce cell death in ovarian cancer cells.
Oncology reports 2008;20(1):219-24.
2008: Stefan Oswald; Jörg König; Dieter Lütjohann; Thomas Giessmann; Heyo K Kroemer; Christian Rimmbach; Dieter Rosskopf; Martin F Fromm; Werner Siegmund
Disposition of ezetimibe is influenced by polymorphisms of the hepatic uptake carrier OATP1B1.
Pharmacogenetics and genomics 2008;18(7):559-68.
2008: O Maas; U Donat; M Frenzel; T Rütz; Heyo K Kroemer; Stephan B Felix; Thomas Krieg
Vardenafil protects isolated rat hearts at reperfusion dependent on GC and PKG.
British journal of pharmacology 2008;154(1):25-31.
2008: Karen May; Veronika Minarikova; Knud Linnemann; Marek Zygmunt; Heyo K Kroemer; Christoph Fusch; Werner Siegmund
Role of the multidrug transporter proteins ABCB1 and ABCC2 in the diaplacental transport of talinolol in the term human placenta.
Drug metabolism and disposition: the biological fate of chemicals 2008;36(4):740-4.
2008: Alexander Riad; Sandra Bien; Matthias Gratz; Felicitas Escher; Dirk Westermann; Markus M Heimesaat; Stefan Bereswill; Thomas Krieg; Stephan B Felix; Heinz-Peter Schultheiss; Heyo K Kroemer; Carsten Tschöpe
Toll-like receptor-4 deficiency attenuates doxorubicin-induced cardiomyopathy in mice.
European journal of heart failure 2008;10(3):233-43.
2007: Angela Kallwellis-Opara; Alexander Staudt; Christiane Trimpert; Michel Noutsias; Uwe Kühl; Matthias Pauschinger; Heinz-Peter Schultheiss; Markus Grube; Michael Böhm; Gert Baumann; Uwe Völker; Heyo K Kroemer; Stephan B Felix
Immunoadsorption and subsequent immunoglobulin substitution decreases myocardial gene expression of desmin in dilated cardiomyopathy.
Journal of molecular medicine (Berlin, Germany) 2007;85(12):1429-35.
2007: Juliane Niessen; Gabriele Jedlitschky; Markus Grube; Sandra Bien; Ulrike Strobel; Christoph A Ritter; Andreas Greinacher; Heyo K Kroemer
Subfractionation and purification of intracellular granule-structures of human platelets: an improved method based on magnetic sorting.
Journal of immunological methods 2007;328(1-2):89-96.
2007: Sandra Bien; Alexander Riad; Christoph A Ritter; Matthias Gratz; Florian Olshausen; Dirk Westermann; Markus Grube; Thomas Krieg; Sabine Ciecholewski; Stephan B Felix; Alexander Staudt; Heinz-Peter Schultheiss; Ralf Ewert; Uwe Völker; Carsten Tschöpe; Heyo K Kroemer
The endothelin receptor blocker bosentan inhibits doxorubicin-induced cardiomyopathy.
Cancer research 2007;67(21):10428-35.
2007: Konrad Meissner; Wolfram Kessler; Henriette Meyer zu Schwabedissen; Katharina Schuster; Kay Saalfeld; Markus Grube; Anna Buck; Gabriele Jedlitschky; Stefan Maier; Tobias Traeger; Jörg Mostertz; Georg Homuth; Claus-Dieter Heidecke; Christian Lehmann; Heyo K Kroemer
Sepsis affects cardiac expression of multidrug resistance protein 5 (MRP5, ABCC5), an ABC-type CGMP export pump.
Shock (Augusta, Ga.) 2007;28(5):564-9.
2007: Stefan Oswald; Markus Grube; Werner Siegmund; Heyo K Kroemer
Transporter-mediated uptake into cellular compartments.
Xenobiotica; the fate of foreign compounds in biological systems 2007;37(10-11):1171-95.
2007: Diana Kuhnke; Gabriele Jedlitschky; Markus Grube; Markus Krohn; Mathias Jucker; Igor Mosyagin; Ingolf Cascorbi; Lary Walker; Heyo K Kroemer; Rolf Warzok; Silke Vogelgesang
MDR1-P-Glycoprotein (ABCB1) Mediates Transport of Alzheimer's amyloid-beta peptides--implications for the mechanisms of Abeta clearance at the blood-brain barrier.
Brain pathology (Zurich, Switzerland) 2007;17(4):347-53.
2007: Janka Reimer; Sandra Bien; Jürgen Sonnemann; James F Beck; Thomas Wieland; Heyo K Kroemer; Christoph A Ritter
Reduced expression of Rho guanine nucleotide dissociation inhibitor-alpha modulates the cytotoxic effect of busulfan in HEK293 cells.
Anti-cancer drugs 2007;18(3):333-40.
2007: Sierk Haenisch; U Zimmermann; Eike Dazert; Christoph J Wruck; Peter Dazert; Werner Siegmund; S Siegmund; Heyo K Kroemer; Rolf Warzok; Ingolf Cascorbi
Influence of polymorphisms of ABCB1 and ABCC2 on mRNA and protein expression in normal and cancerous kidney cortex.
The pharmacogenomics journal 2007;7(1):56-65.
2007: Dieter Rosskopf; Alexa Bornhorst; Christian Rimmbach; Christian Schwahn; Alexander Kayser; Anne Krüger; Grietje Tessmann; Ingrid Geissler; Heyo K Kroemer; Henry Völzke
Comment on "A common genetic variant is associated with adult and childhood obesity".
Science (New York, N.Y.) 2007;315(5809):187; author reply 187.
2007: Kathleen Köck; Markus Grube; Gabriele Jedlitschky; Lena Oevermann; Werner Siegmund; Christoph A Ritter; Heyo K Kroemer
Expression of adenosine triphosphate-binding cassette (ABC) drug transporters in peripheral blood cells: relevance for physiology and pharmacotherapy.
Clinical pharmacokinetics 2007;46(6):449-70.
2007: Markus Grube; Sebastian Reuther; Henriette Meyer zu Schwabedissen; Kathleen Köck; Katrin Draber; Christoph A Ritter; Christoph Fusch; Gabriele Jedlitschky; Heyo K Kroemer
Organic anion transporting polypeptide 2B1 and breast cancer resistance protein interact in the transepithelial transport of steroid sulfates in human placenta.
Drug metabolism and disposition: the biological fate of chemicals 2007;35(1):30-5.
2006: Markus Grube; Kathleen Köck; Stefan Oswald; Katrin Draber; Konrad Meissner; Lothar Eckel; Michael Böhm; Stephan B Felix; Silke Vogelgesang; Gabriele Jedlitschky; Werner Siegmund; Rolf Warzok; Heyo K Kroemer
Organic anion transporting polypeptide 2B1 is a high-affinity transporter for atorvastatin and is expressed in the human heart.
Clinical pharmacology and therapeutics 2006;80(6):607-20.
2006: Peter Dazert; Yalikun Suofu; Markus Grube; Aurel Popa-Wagner; Heyo K Kroemer; Gabriele Jedlitschky; Christof Kessler
Differential regulation of transport proteins in the periinfarct region following reversible middle cerebral artery occlusion in rats.
Neuroscience 2006;142(4):1071-9.
2006: Markus Grube; Kathleen Köck; Susanne Karner; Sebastian Reuther; Christoph A Ritter; Gabriele Jedlitschky; Heyo K Kroemer
Modification of OATP2B1-mediated transport by steroid hormones.
Molecular pharmacology 2006;70(5):1735-41.
2006: Stefan Oswald; Sabine Westrup; Markus Grube; Heyo K Kroemer; Werner Weitschies; Werner Siegmund
Disposition and sterol-lowering effect of ezetimibe in multidrug resistance-associated protein 2-deficient rats.
The Journal of pharmacology and experimental therapeutics 2006;318(3):1293-9.
2006: Gabriele Jedlitschky; Ulrich Hoffmann; Heyo K Kroemer
Structure and function of the MRP2 (ABCC2) protein and its role in drug disposition.
Expert opinion on drug metabolism & toxicology 2006;2(3):351-66.
2006: Henriette Meyer zu Schwabedissen; Annette Dreisbach; Elke Hammer; Christoph Fusch; Michael Hecker; Uwe Völker; Heyo K Kroemer
Direct mass spectrometric identification of ABCB1 (P-glycoprotein/MDR1) from the apical membrane fraction of human placenta using fourier transform ion cyclotron mass spectrometry.
Pharmacogenetics and genomics 2006;16(6):385-9.
2006: Silke Vogelgesang; Markus Glatzel; Lary Walker; Heyo K Kroemer; Adriano Aguzzi; Rolf Warzok
Cerebrovascular P-glycoprotein expression is decreased in Creutzfeldt-Jakob disease.
Acta neuropathologica 2006;111(5):436-43.
2006: Henriette Meyer zu Schwabedissen; Markus Grube; Annette Dreisbach; Gabriele Jedlitschky; Konrad Meissner; Knud Linnemann; Christoph Fusch; Christoph A Ritter; Uwe Völker; Heyo K Kroemer
Epidermal growth factor-mediated activation of the map kinase cascade results in altered expression and function of ABCG2 (BCRP).
Drug metabolism and disposition: the biological fate of chemicals 2006;34(4):524-33.
2006: Stefan Oswald; Sierk Haenisch; Christiane Fricke; Thomas Sudhop; Cornelia Remmler; Thomas Giessmann; Gabriele Jedlitschky; Ulrike Adam; Eike Dazert; Rolf Warzok; Wolfram Wacke; Ingolf Cascorbi; Heyo K Kroemer; Werner Weitschies; Klaus Von Bergmann; Werner Siegmund
Intestinal expression of P-glycoprotein (ABCB1), multidrug resistance associated protein 2 (ABCC2), and uridine diphosphate-glucuronosyltransferase 1A1 predicts the disposition and modulates the effects of the cholesterol absorption inhibitor ezetimibe in humans.
Clinical pharmacology and therapeutics 2006;79(3):206-17.
2006: Markus Grube; Henriette Meyer zu Schwabedissen; Damaris Präger; Jeanette Haney; Klaus-Uwe Möritz; Konrad Meissner; Dieter Rosskopf; Lothar Eckel; Michael Böhm; Gabriele Jedlitschky; Heyo K Kroemer
Uptake of cardiovascular drugs into the human heart: expression, regulation, and function of the carnitine transporter OCTN2 (SLC22A5).
Circulation 2006;113(8):1114-22.
2006: Aurel Popa-Wagner; Ivona Dinca; Suofu Yalikun; Lary Walker; Heyo K Kroemer; Christof Kessler
Accelerated delimitation of the infarct zone by capillary-derived nestin-positive cells in aged rats.
Current neurovascular research 2006;3(1):3-13.
2006: Konrad Meissner; Björn Heydrich; Gabriele Jedlitschky; Henriette Meyer zu Schwabedissen; Igor Mosyagin; Peter Dazert; Lothar Eckel; Silke Vogelgesang; Rolf Warzok; Michael Böhm; Christian Lehmann; Michael Wendt; Ingolf Cascorbi; Heyo K Kroemer
The ATP-binding cassette transporter ABCG2 (BCRP), a marker for side population stem cells, is expressed in human heart.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2006;54(2):215-21.
2006: Peter Meisel; Jürgen Giebel; Christiane Kunert-Keil; Peter Dazert; Heyo K Kroemer; Thomas Kocher
MDR1 gene polymorphisms and risk of gingival hyperplasia induced by calcium antagonists.
Clinical pharmacology and therapeutics 2006;79(1):62-71.
2005: Matthias Gratz; Christiane Kunert-Keil; Ulrich John; Ingolf Cascorbi; Heyo K Kroemer
Identification and functional analysis of genetic variants of the human beta-glucuronidase in a German population sample.
Pharmacogenetics and genomics 2005;15(12):875-81.
2005: Peter Meisel; Christian Schwahn; Ulrich John; Heyo K Kroemer; Thomas Kocher
Calcium antagonists and deep gingival pockets in the population-based SHIP study.
British journal of clinical pharmacology 2005;60(5):552-9.
2005: Kari T Kivistö; Olaf Grisk; ute hofmann; Konrad Meissner; Klaus-Uwe Möritz; Christoph Ritter; Katja A Arnold; Dieter Lutjöohann; Klaus Von Bergmann; Ingrid Klöting; Michel Eichelbaum; Heyo K Kroemer
Disposition of oral and intravenous pravastatin in MRP2-deficient TR- rats.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(11):1593-6.
2005: Peter Meisel; Christian Schwahn; Jan Luedemann; Ulrich John; Heyo K Kroemer; Thomas Kocher
Magnesium deficiency is associated with periodontal disease.
Journal of dental research 2005;84(10):937-41.
2005: Henriette Meyer zu Schwabedissen; Gabriele Jedlitschky; Matthias Gratz; Sierk Haenisch; Knud Linnemann; Christoph Fusch; Ingolf Cascorbi; Heyo K Kroemer
Variable expression of MRP2 (ABCC2) in human placenta: influence of gestational age and cellular differentiation.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(7):896-904.
2005: Christoph A Ritter; Gabriele Jedlitschky; Henriette Meyer zu Schwabedissen; Markus Grube; Kathleen Köck; Heyo K Kroemer
Cellular export of drugs and signaling molecules by the ATP-binding cassette transporters MRP4 (ABCC4) and MRP5 (ABCC5).
Drug metabolism reviews 2005;37(1):253-78.
2005: Henriette Meyer zu Schwabedissen; Markus Grube; Björn Heydrich; Knud Linnemann; Christoph Fusch; Heyo K Kroemer; Gabriele Jedlitschky
Expression, localization, and function of MRP5 (ABCC5), a transporter for cyclic nucleotides, in human placenta and cultured human trophoblasts: effects of gestational age and cellular differentiation.
The American journal of pathology 2005;166(1):39-48.
2005: Markus Grube; Henriette Meyer Zu Schwabedissen; Katrin Draber; Damaris Präger; Klaus-Uwe Möritz; Knud Linnemann; Christoph Fusch; Gabriele Jedlitschky; Heyo K Kroemer
Expression, localization, and function of the carnitine transporter octn2 (slc22a5) in human placenta.
Drug metabolism and disposition: the biological fate of chemicals 2005;33(1):31-7.
2004: Gabriele Jedlitschky; Konstanze Tirschmann; Lena E Lubenow; H Karel Nieuwenhuis; Jan-Willem N Akkerman; Andreas Greinacher; Heyo K Kroemer
The nucleotide transporter MRP4 (ABCC4) is highly expressed in human platelets and present in dense granules, indicating a role in mediator storage.
Blood 2004;104(12):3603-10.
2004: Sandra Bien; Christoph A Ritter; M Kranz; Christian Scharf; Leif Steil; M Hummel; Uwe Völker; Ingolf Cascorbi; Heyo K Kroemer
Influence of doxorubicin on gene expression and protein pattern in HeLa cells.
International journal of clinical pharmacology and therapeutics 2004;42(11):640-1.
2004: Christiane Kunert-Keil; Bernhard Sperker; Sandra Bien; Gabriele Wolf; Markus Grube; Heyo K Kroemer
Involvement of AP-2 binding sites in regulation of human beta-glucuronidase.
Naunyn-Schmiedeberg's archives of pharmacology 2004;370(5):331-9.
2004: Ulrich Hoffmann; Heyo K Kroemer
The ABC transporters MDR1 and MRP2: multiple functions in disposition of xenobiotics and drug resistance.
Drug metabolism reviews 2004;36(3-4):669-701.
2004: Ingolf Cascorbi; Martin Paul; Heyo K Kroemer
Pharmacogenomics of heart failure -- focus on drug disposition and action.
Cardiovascular research 2004;64(1):32-9.
2004: Henriette Meyer zu Schwabedissen; Heyo K Kroemer
[Ezetimib].
Deutsche medizinische Wochenschrift (1946) 2004;129(39):2038-40.
2004: Silke Vogelgesang; Christiane Kunert-Keil; Ingolf Cascorbi; Igor Mosyagin; E Schröder; Uwe Runge; Gabriele Jedlitschky; Heyo K Kroemer; Joachim Oertel; Michael R Gaab; Jens Pahnke; Lary Walker; Rolf Warzok
Expression of multidrug transporters in dysembryoplastic neuroepithelial tumors causing intractable epilepsy.
Clinical neuropathology 2004;23(5):223-31.
2004: Thomas Giessmann; Karen May; Christiane Modess; Danilo Wegner; Ute Hecker; Michael Zschiesche; Peter Dazert; Markus Grube; Eike Schroeder; Rolf Warzok; Ingolf Cascorbi; Heyo K Kroemer; Werner Siegmund
Carbamazepine regulates intestinal P-glycoprotein and multidrug resistance protein MRP2 and influences disposition of talinolol in humans.
Clinical pharmacology and therapeutics 2004;76(3):192-200.
2004: Konrad Meissner; Gabriele Jedlitschky; Henriette Meyer zu Schwabedissen; Peter Dazert; Lothar Eckel; Silke Vogelgesang; Rolf Warzok; Michael Böhm; Christian Lehmann; Michael Wendt; Ingolf Cascorbi; Heyo K Kroemer
Modulation of multidrug resistance P-glycoprotein 1 (ABCB1) expression in human heart by hereditary polymorphisms.
Pharmacogenetics 2004;14(6):381-5.
2004: Silke Vogelgesang; Rolf Warzok; Ingolf Cascorbi; Christiane Kunert-Keil; Eike Schroeder; Heyo K Kroemer; Werner Siegmund; Lary Walker; Jens Pahnke
The role of P-glycoprotein in cerebral amyloid angiopathy; implications for the early pathogenesis of Alzheimer's disease.
Current Alzheimer research 2004;1(2):121-5.
2004: Sandra Bien; Christoph A Ritter; Matthias Gratz; Bernhard Sperker; Jürgen Sonnemann; James F Beck; Heyo K Kroemer
Nuclear factor-kappaB mediates up-regulation of cathepsin B by doxorubicin in tumor cells.
Molecular pharmacology 2004;65(5):1092-102.
2004: Thomas Giessmann; Christiane Modess; Ute Hecker; Michael Zschiesche; Peter Dazert; Christiane Kunert-Keil; Rolf Warzok; Georg Engel; Werner Weitschies; Ingolf Cascorbi; Heyo K Kroemer; Werner Siegmund
CYP2D6 genotype and induction of intestinal drug transporters by rifampin predict presystemic clearance of carvedilol in healthy subjects.
Clinical pharmacology and therapeutics 2004;75(3):213-22.
2003: Markus Grube; Christiane Kunert-Keil; Bernhard Sperker; Heyo K Kroemer
Verapamil regulates activity and mRNA-expression of human beta-glucuronidase in HepG2 cells.
Naunyn-Schmiedeberg's archives of pharmacology 2003;368(6):463-9.
2003: Peter Dazert; Konrad Meissner; Silke Vogelgesang; Björn Heydrich; Lothar Eckel; Michael Böhm; Rolf Warzok; Reinhold Kerb; Ulrich Brinkmann; Elke Schaeffeler; Matthias Schwab; Ingolf Cascorbi; Gabriele Jedlitschky; Heyo K Kroemer
Expression and localization of the multidrug resistance protein 5 (MRP5/ABCC5), a cellular export pump for cyclic nucleotides, in human heart.
The American journal of pathology 2003;163(4):1567-77.
2003: Dana Dressel; Christoph A Ritter; Bernhard Sperker; Markus Grube; Thorsten Maier; Thomas Klingebiel; Werner Siegmund; James F Beck; Heyo K Kroemer
Busulfan induces activin A expression in vitro and in vivo: a possible link to venous occlusive disease.
Clinical pharmacology and therapeutics 2003;74(3):264-74.
2003: Katrin Popowski; Bernhard Sperker; Heyo K Kroemer; Ulrich John; Michael Laule; Karl Stangl; Ingolf Cascorbi
Functional significance of a hereditary adenine insertion variant in the 5'-UTR of the endothelin-1 gene.
Pharmacogenetics 2003;13(8):445-51.
2003: Werner Siegmund; Ingolf Cascorbi; Werner Weitschies; Heyo K Kroemer
[Significance of drug transporter for the internal medicine clinic].
Der Internist 2003;44(2):219-26.
2003: Otto-Erich Brodde; Heyo K Kroemer
Drug-drug interactions of beta-adrenoceptor blockers.
Arzneimittel-Forschung 2003;53(12):814-22.
2003: Christoph A Ritter; Heyo K Kroemer
[What should be considered in the administration of cholesterol synthesis enzyme inhibitors? Interaction and adverse effect potentials of statins].
Pharmazie in unserer Zeit 2003;32(6):490-7.
2002: Christoph A Ritter; Bernhard Sperker; Markus Grube; Dana Dressel; Christiane Kunert-Keil; Heyo K Kroemer
Overexpression of glutathione S-transferase A1-1 in ECV 304 cells protects against busulfan mediated G2-arrest and induces tissue factor expression.
British journal of pharmacology 2002;137(7):1100-6.
2002: Werner Siegmund; Karen Ludwig; Thomas Giessmann; Peter Dazert; Eike Schroeder; Bernhard Sperker; Rolf Warzok; Heyo K Kroemer; Ingolf Cascorbi
The effects of the human MDR1 genotype on the expression of duodenal P-glycoprotein and disposition of the probe drug talinolol.
Clinical pharmacology and therapeutics 2002;72(5):572-83.
2002: Konrad Meissner; Bernhard Sperker; Christiane Karsten; Henriette Meyer Zu Schwabedissen; Ute Seeland; Michael Böhm; Sandra Bien; Peter Dazert; Christiane Kunert-Keil; Silke Vogelgesang; Rolf Warzok; Werner Siegmund; Ingolf Cascorbi; Michael Wendt; Heyo K Kroemer
Expression and localization of P-glycoprotein in human heart: effects of cardiomyopathy.
The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society 2002;50(10):1351-6.
2002: Silke Vogelgesang; Ingolf Cascorbi; Eike Schroeder; Jens Pahnke; Heyo K Kroemer; Werner Siegmund; Christiane Kunert-Keil; Lary Walker; Rolf Warzok
Deposition of Alzheimer's beta-amyloid is inversely correlated with P-glycoprotein expression in the brains of elderly non-demented humans.
Pharmacogenetics 2002;12(7):535-41.
2002: Mikko Niemi; Ingolf Cascorbi; Ramona Timm; Heyo K Kroemer; Pertti J Neuvonen; Kari T Kivistö
Glyburide and glimepiride pharmacokinetics in subjects with different CYP2C9 genotypes.
Clinical pharmacology and therapeutics 2002;72(3):326-32.
2002: Werner Siegmund; Stephan Altmannsberger; Andrea Paneitz; Ute Hecker; Michael Zschiesche; Gerd Franke; Wieland Meng; Rolf Warzok; Eike Schroeder; Bernhard Sperker; Bernd Terhaag; Ingolf Cascorbi; Heyo K Kroemer
Effect of levothyroxine administration on intestinal P-glycoprotein expression: consequences for drug disposition.
Clinical pharmacology and therapeutics 2002;72(3):256-64.
2002: Dagmar Busse; Gudrun Würthwein; Christiane Hinske; Georg Hempel; Martin F Fromm; Michel Eichelbaum; Heyo K Kroemer; Friedrich W Busch
Pharmacokinetics of intravenous etoposide in patients with breast cancer: influence of dose escalation and cyclophosphamide and doxorubicin coadministration.
Naunyn-Schmiedeberg's archives of pharmacology 2002;366(3):218-25.
2002: Bernhard Sperker; Thomas E Mürdter; Janne T Backman; Peter Fritz; Heyo K Kroemer
Expression of active human beta-glucuronidase in Sf9 cells infected with recombinant baculovirus.
Life sciences 2002;71(13):1547-57.
2002: Jörn Lötsch; Bernhard Sperker; Heyo K Kroemer; Gerd Geisslinger
Verapamil decreases glucuronidase activity in the gut.
Biochemical pharmacology 2002;63(8):1575-8.
2002: Thomas E Mürdter; Godehard Friedel; Janne T Backman; Monika McClellan; Monika Schick; Manfred Gerken; Klaus Bosslet; Peter Fritz; Heikki Toomes; Heyo K Kroemer; Bernhard Sperker
Dose optimization of a doxorubicin prodrug (HMR 1826) in isolated perfused human lungs: low tumor pH promotes prodrug activation by beta-glucuronidase.
The Journal of pharmacology and experimental therapeutics 2002;301(1):223-8.
2002: Michael Zschiesche; Girum Lakew Lemma; Klaus-Jürgen Klebingat; Gerd Franke; Bernd Terhaag; Anna Hoffmann; Thomas Gramatté; Heyo K Kroemer; Werner Siegmund
Stereoselective disposition of talinolol in man.
Journal of pharmaceutical sciences 2002;91(2):303-11.
2001: Janet K Coller; Peter Fritz; Uli Zanger; Isabel Siegle; Michel Eichelbaum; Heyo K Kroemer; Thomas E Mürdter
Distribution of microsomal epoxide hydrolase in humans: an immunohistochemical study in normal tissues, and benign and malignant tumours.
The Histochemical journal 2001;33(6):329-36.
2001: Bernhard Sperker; Céline Tomkiewicz; O Burk; Robert Barouki; Heyo K Kroemer
Regulation of human beta-glucuronidase by A23187 and thapsigargin in the hepatoma cell line HepG2.
Molecular pharmacology 2001;59(2):177-82.
2001: S H Altmannsberger; Andrea Paneitz; Werner Siegmund; Heyo K Kroemer
[Pharmacologic basics: the effect of AT1 receptor antagonists].
Pharmazie in unserer Zeit 2001;30(4):296-302.
2000: Thomas E Mürdter; Albert Linder; Godehard Friedel; Monika McClellan; Frank Bohnenstengel; Bernhard Sperker; Heyo K Kroemer; Heikki Toomes; Lutz Freitag; Peter Fritz
[Pharmacokinetics of cyclophosphamide, adriamycin and adriamycin prodrug (HMR 1928) using an ex vivo isolated perfused human lung model (IHLP)].
Pneumologie (Stuttgart, Germany) 2000;54(11):494-8.
2000: Martin F Fromm; Hans-Martin Kauffmann; P Fritz; Oliver Burk; Heyo K Kroemer; Rolf Warzok; Michel Eichelbaum; Werner Siegmund; Dieter Schrenk
The effect of rifampin treatment on intestinal expression of human MRP transporters.
The American journal of pathology 2000;157(5):1575-80.
2000: ute hofmann; M Pecia; Georg Heinkele; Karin Dilger; Heyo K Kroemer; Michel Eichelbaum
Determination of propafenone and its phase I and phase II metabolites in plasma and urine by high-performance liquid chromatography-electrospray ionization mass spectrometry.
Journal of chromatography. B, Biomedical sciences and applications 2000;748(1):113-23.
2000: K Westphal; Anita Weinbrenner; Michael Zschiesche; Gerd Franke; M Knoke; Reinhard Oertel; P Fritz; Oliver Von Richter; Rolf Warzok; Thomas Hachenberg; Hans-Martin Kauffmann; Dieter Schrenk; Bernd Terhaag; Heyo K Kroemer; Werner Siegmund
Induction of P-glycoprotein by rifampin increases intestinal secretion of talinolol in human beings: a new type of drug/drug interaction.
Clinical pharmacology and therapeutics 2000;68(4):345-55.
2000: Bernhard Sperker; U Werner; Thomas E Mürdter; C Tekkaya; Peter Fritz; Rainer Wacke; Ulrich Adam; Manfred Gerken; Bernd Drewelow; Heyo K Kroemer
Expression and function of beta-glucuronidase in pancreatic cancer: potential role in drug targeting.
Naunyn-Schmiedeberg's archives of pharmacology 2000;362(2):110-5.
2000: K Westphal; Anita Weinbrenner; Thomas Giessmann; M Stuhr; Gerd Franke; Michael Zschiesche; Reinhard Oertel; Bernd Terhaag; Heyo K Kroemer; Werner Siegmund
Oral bioavailability of digoxin is enhanced by talinolol: evidence for involvement of intestinal P-glycoprotein.
Clinical pharmacology and therapeutics 2000;68(1):6-12.
2000: Andrea Paneitz; Konrad Meissner; Heyo K Kroemer
[Drug interactions: new mechanisms and clinical relevance].
Der Internist 2000;41(4):338-43.
2000: Frank Bohnenstengel; Godehard Friedel; Christoph A Ritter; Monika McClellan; Peter Fritz; Michel Eichelbaum; Albert Linder; Heikki Toomes; Rainer Dierkesmann; Heyo K Kroemer
Variability of cyclophosphamide uptake into human bronchial carcinoma: consequences for local bioactivation.
Cancer chemotherapy and pharmacology 2000;45(1):63-8.
1999: Karin Dilger; B Greiner; Martin F Fromm; ute hofmann; Heyo K Kroemer; Michel Eichelbaum
Consequences of rifampicin treatment on propafenone disposition in extensive and poor metabolizers of CYP2D6.
Pharmacogenetics 1999;9(5):551-9.
1999: Peter Fritz; R Seizer-Schmidt; Thomas E Mürdter; Heyo K Kroemer; Walter Aulitzky; S André; Hans-Joachim Gabius; Godehard Friedel; Heikki Toomes; Isabel Siegle
Ligands for Viscum album agglutinin and galectin-1 in human lung cancer: is there any prognostic relevance?
Acta histochemica 1999;101(3):239-53.
1999: B Greiner; Michel Eichelbaum; P Fritz; Heinz Peter Kreichgauer; Oliver Von Richter; J Zundler; Heyo K Kroemer
The role of intestinal P-glycoprotein in the interaction of digoxin and rifampin.
The Journal of clinical investigation 1999;104(2):147-53.
1999: Christoph A Ritter; Frank Bohnenstengel; ute hofmann; Heyo K Kroemer; Bernhard Sperker
Determination of tetrahydrothiophene formation as a probe of in vitro busulfan metabolism by human glutathione S-transferase A1-1: use of a highly sensitive gas chromatographic-mass spectrometric method.
Journal of chromatography. B, Biomedical sciences and applications 1999;730(1):25-31.
1999: Frank Bohnenstengel; Heyo K Kroemer; Bernhard Sperker
In vitro cleavage of paracetamol glucuronide by human liver and kidney beta-glucuronidase: determination of paracetamol by capillary electrophoresis.
Journal of chromatography. B, Biomedical sciences and applications 1999;721(2):295-9.
1999: Dagmar Busse; Friedrich W Busch; E Schweizer; Frank Bohnenstengel; Michel Eichelbaum; P Fischer; K Schumacher; Walter Aulitzky; Heyo K Kroemer
Fractionated administration of high-dose cyclophosphamide: influence on dose-dependent changes in pharmacokinetics and metabolism.
Cancer chemotherapy and pharmacology 1999;43(3):263-8.
1998: Dagmar Busse; Heyo K Kroemer; Bernhard Sperker; Thomas E Mürdter
[Treatment of cancer with cytostatics: results with high dose therapy with cyclophosphamide and drug targeting with doxorubicin].
Pharmazie in unserer Zeit 1998;27(5):216-22.
1998: Thomas E Mürdter; Bernhard Sperker; Klaus Bosslet; Peter Fritz; Heyo K Kroemer
Simultaneous high-performance liquid chromatographic determination of a glucuronyl prodrug of doxorubicin, doxorubicin and its metabolites in human lung tissue.
Journal of chromatography. B, Biomedical sciences and applications 1998;709(2):289-95.
1998: Klaus Bosslet; R Straub; M Blumrich; J Czech; Manfred Gerken; Bernhard Sperker; Heyo K Kroemer; Jean-Pierre Gesson; M Koch; Claude Monneret
Elucidation of the mechanism enabling tumor selective prodrug monotherapy.
Cancer research 1998;58(6):1195-201.
1998: Martin F Fromm; Karin Dilger; Dagmar Busse; Heyo K Kroemer; Michel Eichelbaum; Ulrich Klotz
Gut wall metabolism of verapamil in older people: effects of rifampicin-mediated enzyme induction.
British journal of clinical pharmacology 1998;45(3):247-55.
1997: Kari T Kivistö; Ernst-Ulrich Griese; T Stüven; Peter Fritz; G Friedel; Heyo K Kroemer; Uli Zanger
Analysis of CYP2D6 expression in human lung: implications for the association between CYP2D6 activity and susceptibility to lung cancer.
Pharmacogenetics 1997;7(4):295-302.
1997: Bernhard Sperker; Janne T Backman; Heyo K Kroemer
The role of beta-glucuronidase in drug disposition and drug targeting in humans.
Clinical pharmacokinetics 1997;33(1):18-31.
1997: Thomas E Mürdter; Bernhard Sperker; K T Kivistö; Monika McClellan; Peter Fritz; Godehard Friedel; Albert Linder; Klaus Bosslet; Heikki Toomes; Rainer Dierkesmann; Heyo K Kroemer
Enhanced uptake of doxorubicin into bronchial carcinoma: beta-glucuronidase mediates release of doxorubicin from a glucuronide prodrug (HMR 1826) at the tumor site.
Cancer research 1997;57(12):2440-5.
1997: Dagmar Busse; Friedrich W Busch; Frank Bohnenstengel; Michel Eichelbaum; P Fischer; J Opalinska; K Schumacher; E Schweizer; Heyo K Kroemer
Dose escalation of cyclophosphamide in patients with breast cancer: consequences for pharmacokinetics and metabolism.
Journal of clinical oncology : official journal of the American Society of Clinical Oncology 1997;15(5):1885-96.
1997: Bernhard Sperker; Thomas E Mürdter; M Schick; K Eckhardt; Klaus Bosslet; Heyo K Kroemer
Interindividual variability in expression and activity of human beta-glucuronidase in liver and kidney: consequences for drug metabolism.
The Journal of pharmacology and experimental therapeutics 1997;281(2):914-20.
1997: Frank Bohnenstengel; Michel Eichelbaum; E Golbs; Heyo K Kroemer
High-performance liquid chromatographic determination of acrolein as a marker for cyclophosphamide bioactivation in human liver microsomes.
Journal of chromatography. B, Biomedical sciences and applications 1997;692(1):163-8.
1997: Dagmar Busse; Heyo K Kroemer
Dose-dependency of oxazaphosphorine pharmacokinetics.
International journal of clinical pharmacology and therapeutics 1997;35(2):71-2.
1997: Kari T Kivistö; Heyo K Kroemer
Use of probe drugs as predictors of drug metabolism in humans.
Journal of clinical pharmacology 1997;37(1 Suppl):40S-48S.
1996: Bernhard Sperker; M Schick; Heyo K Kroemer
High-performance liquid chromatographic quantification of 4-methylumbelliferyl-beta-D-glucuronide as a probe for human beta-glucuronidase activity in tissue homogenates.
Journal of chromatography. B, Biomedical applications 1996;685(1):181-4.
1996: T Stüven; Ernst-Ulrich Griese; Heyo K Kroemer; Michel Eichelbaum; Uli Zanger
Rapid detection of CYP2D6 null alleles by long distance- and multiplex-polymerase chain reaction.
Pharmacogenetics 1996;6(5):417-21.
1996: N Holtbecker; Martin F Fromm; Heyo K Kroemer; E E Ohnhaus; H Heidemann
The nifedipine-rifampin interaction. Evidence for induction of gut wall metabolism.
Drug metabolism and disposition: the biological fate of chemicals 1996;24(10):1121-3.
1996: Martin F Fromm; Dagmar Busse; Heyo K Kroemer; Michel Eichelbaum
Differential induction of prehepatic and hepatic metabolism of verapamil by rifampin.
Hepatology (Baltimore, Md.) 1996;24(4):796-801.
1996: K T Kivistö; G Bookjans; Martin F Fromm; Ernst-Ulrich Griese; Peter A Münzel; Heyo K Kroemer
Expression of CYP3A4, CYP3A5 and CYP3A7 in human duodenal tissue.
British journal of clinical pharmacology 1996;42(3):387-9.
1996: Heyo K Kroemer; Martin F Fromm; Michel Eichelbaum
Stereoselectivity in drug metabolism and action: effects of enzyme inhibition and induction.
Therapeutic drug monitoring 1996;18(4):388-92.
1996: J P Kévorkian; C Michel; U Hofmann; E Jacqz-Aigrain; Heyo K Kroemer; M N Peraldi; Michel Eichelbaum; Patrice Jaillon; Christian Funck-Brentano
Assessment of individual CYP2D6 activity in extensive metabolizers with renal failure: comparison of sparteine and dextromethorphan.
Clinical pharmacology and therapeutics 1996;59(5):583-92.
1996: Frank Bohnenstengel; ute hofmann; Michel Eichelbaum; Heyo K Kroemer
Characterization of the cytochrome P450 involved in side-chain oxidation of cyclophosphamide in humans.
European journal of clinical pharmacology 1996;51(3-4):297-301.
1996: Peter Fritz; E Behrle; Uli Zanger; Thomas E Mürdter; P Schwarzmann; Heyo K Kroemer
Immunohistochemical assessment of human microsomal epoxide hydrolase in primary and secondary liver neoplasm: a quantitative approach.
Xenobiotica; the fate of foreign compounds in biological systems 1996;26(1):107-16.
1996: Heyo K Kroemer; S Botsch; G Heinkele; M Schick
In vitro assessment of various cytochromes P450 and glucuronosyltransferases using the antiarrhythmic propafenone as a probe drug.
Methods in enzymology 1996;272():99-105.
1996: K T Kivistö; Ernst-Ulrich Griese; Peter Fritz; Albert Linder; Jukka Hakkola; Hannu Raunio; P Beaune; Heyo K Kroemer
Expression of cytochrome P 450 3A enzymes in human lung: a combined RT-PCR and immunohistochemical analysis of normal tissue and lung tumours.
Naunyn-Schmiedeberg's archives of pharmacology 1996;353(2):207-12.
1995: Dagmar Busse; J Cosme; P Beaune; Heyo K Kroemer; Michel Eichelbaum
Cytochromes of the P450 2C subfamily are the major enzymes involved in the O-demethylation of verapamil in humans.
Naunyn-Schmiedeberg's archives of pharmacology 1995;353(1):116-21.
1995: K T Kivistö; Heyo K Kroemer; Michel Eichelbaum
The role of human cytochrome P450 enzymes in the metabolism of anticancer agents: implications for drug interactions.
British journal of clinical pharmacology 1995;40(6):523-30.
1995: Frank Bohnenstengel; S Johnson; ute hofmann; Michel Eichelbaum; Heyo K Kroemer
Direct gas chromatographic determination of dechloroethylcyclophosphamide following microsomal incubation of cyclophosphamide.
Journal of chromatography. B, Biomedical applications 1995;672(2):271-6.
1995: Martin F Fromm; Heyo K Kroemer
[Mirror, mirror on the wall--stereoselectivity of drug effects].
Fortschritte der Medizin 1995;113(24):343-5.
1995: L Firkusny; Heyo K Kroemer; Michel Eichelbaum
In vitro characterization of cytochrome P450 catalysed metabolism of the antiemetic tropisetron.
Biochemical pharmacology 1995;49(12):1777-84.
1995: Heyo K Kroemer; Michel Eichelbaum
"It's the genes, stupid". Molecular bases and clinical consequences of genetic cytochrome P450 2D6 polymorphism.
Life sciences 1995;56(26):2285-98.
1995: K T Kivistö; Albert Linder; Godehard Friedel; P Beaune; C Belloc; Heyo K Kroemer; Peter Fritz
Immunohistochemical localization of cytochrome P450 2E1 in human pulmonary carcinoma and normal bronchial tissue.
Virchows Archiv : an international journal of pathology 1995;426(3):243-7.
1995: K T Kivistö; Peter Fritz; Albert Linder; Godehard Friedel; P Beaune; Heyo K Kroemer
Immunohistochemical localization of cytochrome P450 3A in human pulmonary carcinomas and normal bronchial tissue.
Histochemistry and cell biology 1995;103(1):25-9.
1995: Martin F Fromm; S Botsch; G Heinkele; J Evers; Heyo K Kroemer
Influence of renal function on the steady-state pharmacokinetics of the antiarrhythmic propafenone and its phase I and phase II metabolites.
European journal of clinical pharmacology 1995;48(3-4):279-83.
1994: J Evers; M Eichelbaum; Heyo K Kroemer
Unpredictability of flecainide plasma concentrations in patients with renal failure: relationship to side effects and sudden death?
Therapeutic drug monitoring 1994;16(4):349-51.
1994: Heyo K Kroemer; Martin F Fromm; K Bühl; H Terefe; Gottfried Blaschke; Michel Eichelbaum
An enantiomer-enantiomer interaction of (S)- and (R)-propafenone modifies the effect of racemic drug therapy.
Circulation 1994;89(5):2396-400.
1994: Christian Funck-Brentano; Laurent Becquemont; Heyo K Kroemer; K Bühl; N G Knebel; Michel Eichelbaum; Patrice Jaillon
Variable disposition kinetics and electrocardiographic effects of flecainide during repeated dosing in humans: contribution of genetic factors, dose-dependent clearance, and interaction with amiodarone.
Clinical pharmacology and therapeutics 1994;55(3):256-69.
1994: S Botsch; G Heinkele; C O Meese; Michel Eichelbaum; Heyo K Kroemer
Rapid determination of CYP2D6 phenotype during propafenone therapy by analysing urinary excretion of propafenone glucuronides.
European journal of clinical pharmacology 1994;46(2):133-5.
1993: Heyo K Kroemer; J C Gautier; P Beaune; C Henderson; C R Wolf; Michel Eichelbaum
Identification of P450 enzymes involved in metabolism of verapamil in humans.
Naunyn-Schmiedeberg's archives of pharmacology 1993;348(3):332-7.
1993: P Fritz; E Behrle; P Beaune; M Eichelbaum; Heyo K Kroemer
Differential expression of drug metabolizing enzymes in primary and secondary liver neoplasm: immunohistochemical characterization of cytochrome P4503A and glutathione-S-transferase.
Histochemistry 1993;99(6):443-51.
1993: S Botsch; J C Gautier; P Beaune; Michel Eichelbaum; Heyo K Kroemer
Identification and characterization of the cytochrome P450 enzymes involved in N-dealkylation of propafenone: molecular base for interaction potential and variable disposition of active metabolites.
Molecular pharmacology 1993;43(1):120-6.
1992: Michel Eichelbaum; Heyo K Kroemer; Gerd Mikus
Genetically determined differences in drug metabolism as a risk factor in drug toxicity.
Toxicology letters 1992;64-65 Spec No():115-22.
1992: Heyo K Kroemer; U Klotz
Glucuronidation of drugs. A re-evaluation of the pharmacological significance of the conjugates and modulating factors.
Clinical pharmacokinetics 1992;23(4):292-310.
1992: Heyo K Kroemer; H Echizen; H Heidemann; Michel Eichelbaum
Predictability of the in vivo metabolism of verapamil from in vitro data: contribution of individual metabolic pathways and stereoselective aspects.
The Journal of pharmacology and experimental therapeutics 1992;260(3):1052-7.
1991: U Klotz; Heyo K Kroemer
[The interaction potential of H2 receptor antagonists. A short current review].
Fortschritte der Medizin 1991;109(28):574-6.
1991: Heyo K Kroemer; C Fischer; C O Meese; Michel Eichelbaum
Enantiomer/enantiomer interaction of (S)- and (R)-propafenone for cytochrome P450IID6-catalyzed 5-hydroxylation: in vitro evaluation of the mechanism.
Molecular pharmacology 1991;40(1):135-42.
1991: Annette Gross; Heyo K Kroemer; Michel Eichelbaum
Genetic polymorphism of drug metabolism in humans.
Advances in experimental medicine and biology 1991;283():627-40.
1990: J T Lee; Heyo K Kroemer; D J Silberstein; Christian Funck-Brentano; M D Lineberry; Alastair J J Wood; Dan Mark Roden; Raymond L Woosley
The role of genetically determined polymorphic drug metabolism in the beta-blockade produced by propafenone.
The New England journal of medicine 1990;322(25):1764-8.
1990: Gerd Mikus; Michel Eichelbaum; C Fischer; S Gumulka; U Klotz; Heyo K Kroemer
Interaction of verapamil and cimetidine: stereochemical aspects of drug metabolism, drug disposition and drug action.
The Journal of pharmacology and experimental therapeutics 1990;253(3):1042-8.
1990: Christian Funck-Brentano; Heyo K Kroemer; J T Lee; Dan Mark Roden
Propafenone.
The New England journal of medicine 1990;322(8):518-25.
1990: Jacques Turgeon; Heyo K Kroemer; C Prakash; Ian A Blair; Dan Mark Roden
Stereoselective determination of flecainide in human plasma by high-performance liquid chromatography with fluorescence detection.
Journal of pharmaceutical sciences 1990;79(2):91-5.
1989: Heyo K Kroemer; Jacques Turgeon; R A Parker; Dan Mark Roden
Flecainide enantiomers: disposition in human subjects and electrophysiologic actions in vitro.
Clinical pharmacology and therapeutics 1989;46(5):584-90.
1989: Heyo K Kroemer; Christian Funck-Brentano; D J Silberstein; Alastair J J Wood; Michel Eichelbaum; Raymond L Woosley; Dan Mark Roden
Stereoselective disposition and pharmacologic activity of propafenone enantiomers.
Circulation 1989;79(5):1068-76.
1989: Christian Funck-Brentano; Heyo K Kroemer; H Pavlou; Raymond L Woosley; Dan Mark Roden
Genetically-determined interaction between propafenone and low dose quinidine: role of active metabolites in modulating net drug effect.
British journal of clinical pharmacology 1989;27(4):435-44.